Danio rerio

16 known processes

hfe2

hemochromatosis type 2

(Aliases: MGC136698,hjv,id:ibd3464,RGMr,DL-M,zgc:136698,MGC162101,wu:fb38f10,RGMC)

hfe2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular aromatic compound metabolic processGO:00067252950.287
Mouse
neuroblast proliferationGO:000740520.274
regulation of nitrogen compound metabolic processGO:00511712510.202
Mouse Worm
rna biosynthetic processGO:00327741810.198
Mouse
regulation of biosynthetic processGO:00098892500.198
Mouse Worm
gene expressionGO:00104672520.194
Mouse
heart morphogenesisGO:00030071560.185
cellular component morphogenesisGO:00329893360.183
regulation of rna biosynthetic processGO:20011412130.183
Mouse Worm
positive regulation of gene expressionGO:0010628710.162
Mouse
cell motilityGO:00488702440.149
stem cell proliferationGO:007208940.143
mesodermal cell migrationGO:0008078120.135
blood vessel developmentGO:00015682460.134
vasculature developmentGO:00019442780.132
nucleocytoplasmic transportGO:000691340.128
macromolecule biosynthetic processGO:00090592270.125
Mouse
morphogenesis of an epitheliumGO:00020093330.119
biosynthetic processGO:00090582940.118
Mouse
rna metabolic processGO:00160702190.117
Mouse
cellular macromolecule metabolic processGO:00442603910.114
Mouse
cellular component movementGO:00069283350.113
tube morphogenesisGO:00352393490.111
Worm
organic cyclic compound metabolic processGO:19013603010.108
Mouse
skeletal muscle organ developmentGO:0060538780.104
sensory organ developmentGO:00074233930.103
localization of cellGO:00516742440.103
regulation of cellular biosynthetic processGO:00313262450.100
Mouse Worm
aromatic compound biosynthetic processGO:00194382170.097
Mouse
regulation of cellular metabolic processGO:00313233200.097
Mouse Worm
embryonic heart tube developmentGO:00350501330.096
regulation of metabolic processGO:00192223590.095
Mouse Worm
chordate embryonic developmentGO:00430092710.095
heart developmentGO:00075073130.095
cellular response to external stimulusGO:007149620.094
response to nutrientGO:000758430.093
system processGO:00030081850.088
cell migrationGO:00164772370.086
cell migration involved in gastrulationGO:0042074790.086
establishment of protein localization to organelleGO:007259440.084
embryonic organ developmentGO:00485683810.081
determination of bilateral symmetryGO:00098552040.080
cellular nitrogen compound metabolic processGO:00346412900.078
Mouse
regulation of protein targetingGO:190353320.078
sensory perception of chemical stimulusGO:000760630.076
nuclear transportGO:005116940.075
regulation of cellular macromolecule biosynthetic processGO:20001122220.074
Mouse Worm
ameboidal type cell migrationGO:00016671430.073
cellular biosynthetic processGO:00442492860.070
Mouse
organic substance biosynthetic processGO:19015762890.070
Mouse
single organism nuclear importGO:190259330.069
regulation of extrinsic apoptotic signaling pathwayGO:200123630.068
nuclear importGO:005117030.068
nucleic acid metabolic processGO:00903042440.067
Mouse
regulation of protein import into nucleusGO:004230620.065
heterocycle biosynthetic processGO:00181302150.065
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.065
response to external stimulusGO:00096052640.062
segmentationGO:0035282970.061
agingGO:000756820.059
cellular macromolecule biosynthetic processGO:00346452240.058
Mouse
regulation of macromolecule metabolic processGO:00602553170.057
Mouse Worm
regulation of nucleic acid templated transcriptionGO:19035062130.056
Mouse Worm
muscle tissue developmentGO:00605371100.056
regulation of gene expressionGO:00104682650.056
Mouse Worm
chemosensory behaviorGO:000763510.055
camera type eye developmentGO:00430102220.055
regionalizationGO:00030022740.055
nucleobase containing compound biosynthetic processGO:00346542050.054
Mouse
neural tube patterningGO:0021532330.053
positive regulation of transcription dna templatedGO:0045893570.051
Mouse
protein import into nucleusGO:000660630.050
peripheral nervous system developmentGO:0007422550.050
brain developmentGO:00074202930.050
camera type eye morphogenesisGO:00485931080.050
gastrulationGO:00073692080.050
Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.050
Mouse Worm
regulation of stem cell proliferationGO:007209120.050
locomotionGO:00400113130.049
sprouting angiogenesisGO:0002040530.049
protein importGO:001703830.049
regulation of macromolecule biosynthetic processGO:00105562250.048
Mouse Worm
regulation of developmental processGO:00507932470.047
Worm
nucleobase containing compound metabolic processGO:00061392740.046
Mouse
maintenance of locationGO:005123540.046
eye developmentGO:00016542770.046
cellular protein catabolic processGO:004425740.045
heterocycle metabolic processGO:00464832900.044
Mouse
regulation of nucleocytoplasmic transportGO:004682220.044
muscle organ developmentGO:00075171010.044
skeletal muscle tissue developmentGO:0007519670.044
cell surface receptor signaling pathwayGO:00071663250.043
Mouse Worm
positive regulation of transportGO:005105020.043
regulation of establishment of protein localizationGO:007020140.043
cell proliferationGO:0008283800.042
protein localization to nucleusGO:003450430.042
cellular response to extracellular stimulusGO:003166820.042
gland developmentGO:00487321430.041
regulation of protein transportGO:005122330.041
convergent extensionGO:00600261180.041
skeletal muscle fiber developmentGO:0048741350.040
myotube differentiationGO:0014902450.040
cell morphogenesisGO:00009022890.040
single organism organelle organizationGO:19025891990.040
regulation of protein localization to nucleusGO:190018020.040
heart processGO:0003015710.040
central nervous system developmentGO:00074173870.039
striated muscle tissue developmentGO:00147061100.039
sensory perception of smellGO:000760820.039
regulation of skeletal muscle fiber developmentGO:004874220.038
taxisGO:00423301090.038
regulation of transcription dna templatedGO:00063552130.038
Mouse Worm
cellular protein metabolic processGO:00442671290.038
positive regulation of cellular biosynthetic processGO:0031328680.038
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.037
Mouse
regulation of organelle assemblyGO:190211540.037
cell part morphogenesisGO:00329902460.037
cartilage condensationGO:000150230.036
cell matrix adhesionGO:000716040.036
response to glucoseGO:000974930.035
larval developmentGO:000216420.035
Worm
wnt signaling pathwayGO:0016055800.035
biological adhesionGO:0022610400.035
regulation of multicellular organism growthGO:004001440.035
Worm
digestive tract developmentGO:00485652650.035
Worm
positive regulation of nucleobase containing compound metabolic processGO:0045935690.034
Mouse
cell projection morphogenesisGO:00488582440.034
cell projection organizationGO:00300302840.033
protein metabolic processGO:00195381830.033
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.033
striated muscle cell differentiationGO:00511461290.033
regulation of anatomical structure morphogenesisGO:00226031300.033
digestive system developmentGO:00551232890.032
Worm
specification of symmetryGO:00097992040.032
regulation of dna replicationGO:000627530.032
epithelial tube morphogenesisGO:00605621480.032
chemotaxisGO:00069351040.032
epithelial cell migrationGO:0010631250.032
blood vessel morphogenesisGO:00485142160.032
organic cyclic compound biosynthetic processGO:19013622230.032
Mouse
response to chemicalGO:00422213200.032
embryo development ending in birth or egg hatchingGO:00097922710.031
response to hexoseGO:000974630.031
regulation of cell communicationGO:00106462320.031
Mouse Worm
digestive tract morphogenesisGO:00485462310.031
Worm
generation of neuronsGO:00486993850.031
cellular response to biotic stimulusGO:007121630.031
signal transductionGO:00071654550.030
Mouse Worm
positive regulation of cellular metabolic processGO:0031325940.030
Mouse
regulation of multicellular organismal processGO:00512392770.030
Worm
axonal fasciculationGO:0007413110.030
myotube cell developmentGO:0014904350.030
nucleic acid templated transcriptionGO:00976591810.030
Mouse
response to monosaccharideGO:003428430.030
cell morphogenesis involved in differentiationGO:00009041950.030
negative regulation of biological processGO:00485193040.029
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.029
Mouse Worm
head developmentGO:00603223030.029
heart loopingGO:0001947940.029
response to carbohydrateGO:000974330.029
positive regulation of cell cycleGO:004578730.029
regulation of cytokine productionGO:000181730.028
regulation of wound healingGO:006104120.027
neuron projection developmentGO:00311751800.027
transcription dna templatedGO:00063511810.027
Mouse
response to vitaminGO:003327330.027
somitogenesisGO:0001756870.027
muscle cell developmentGO:00550011150.027
adult behaviorGO:003053420.026
regulation of cytoplasmic transportGO:190364940.026
post embryonic morphogenesisGO:000988640.026
establishment of localizationGO:00512342440.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.026
Mouse Worm
positive regulation of metabolic processGO:00098931080.025
Mouse
somite developmentGO:0061053960.025
programmed cell deathGO:00125011190.025
regulation of multicellular organismal developmentGO:20000262230.025
Worm
neurological system processGO:0050877620.025
positive regulation of cellular processGO:00485222010.025
Mouse
stem cell divisionGO:001714510.025
nitrogen compound metabolic processGO:00068073190.025
Mouse
negative regulation of protein phosphorylationGO:000193340.024
cell cycleGO:0007049930.024
determination of heart left right asymmetryGO:00613711170.023
response to stressGO:00069502630.023
protein targeting to nucleusGO:004474430.023
regulation of intracellular protein transportGO:003315730.022
phosphate containing compound metabolic processGO:00067961080.022
determination of left right symmetryGO:00073681790.022
notochord developmentGO:0030903540.022
positive regulation of biological processGO:00485182530.022
Mouse
response to abiotic stimulusGO:00096281220.022
skin developmentGO:0043588540.021
regulation of skeletal muscle tissue developmentGO:004864140.021
circulatory system processGO:0003013870.021
transcription from rna polymerase ii promoterGO:0006366800.021
Mouse
single organism localizationGO:19025782250.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
Mouse Worm
anterior posterior pattern specificationGO:00099521520.021
growthGO:00400071740.021
Worm
cell differentiation in spinal cordGO:0021515400.020
positive regulation of cell activationGO:005086710.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
sensory organ morphogenesisGO:00905962000.020
positive regulation of developmental processGO:0051094500.020
tissue remodelingGO:004877140.020
ubiquitin dependent protein catabolic processGO:000651130.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
negative regulation of cytoplasmic transportGO:190365020.020
detection of chemical stimulusGO:000959340.020
cellular response to lipopolysaccharideGO:007122230.020
neuron projection morphogenesisGO:00488121610.019
muscle cell differentiationGO:00426921390.019
cell fate commitmentGO:0045165990.019
Worm
positive regulation of cell divisionGO:005178120.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.019
hemopoiesisGO:00300971830.019
single organism metabolic processGO:00447102170.019
epithelium migrationGO:0090132250.019
positive regulation of muscle cell differentiationGO:005114910.018
regulation of cell cycleGO:0051726520.018
angiogenesisGO:00015251580.018
defense response to fungusGO:005083220.018
regulation of primary metabolic processGO:00800903110.018
Mouse Worm
apoptotic processGO:00069151160.018
bmp signaling pathwayGO:0030509520.018
Mouse Worm
regulation of biological qualityGO:00650082630.018
Mouse
formation of anatomical boundaryGO:0048859140.018
leukocyte migrationGO:0050900150.018
hormone transportGO:000991420.017
positive regulation of biosynthetic processGO:0009891680.017
Mouse
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082340.017
diencephalon developmentGO:0021536580.017
cell morphogenesis involved in neuron differentiationGO:00486671630.016
axon guidanceGO:0007411860.016
positive regulation of secretionGO:005104710.016
cellular amine metabolic processGO:004410620.016
positive regulation of macromolecule metabolic processGO:0010604930.016
Mouse
multicellular organism growthGO:003526440.016
Worm
negative regulation of protein transportGO:005122430.016
skeletal system developmentGO:00015011810.016
mitotic cell cycle processGO:1903047480.016
positive regulation of cell adhesionGO:004578510.015
regulation of bmp signaling pathwayGO:0030510390.015
Mouse Worm
protein acetylationGO:000647320.015
transportGO:00068102200.015
epithelial cell differentiationGO:00308551160.015
protein modification processGO:00362111000.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
Mouse
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.015
organelle organizationGO:00069962270.015
alcohol biosynthetic processGO:004616520.015
endothelial cell fate commitmentGO:006083930.015
defense response to other organismGO:0098542330.015
tissue migrationGO:0090130370.015
phosphorylationGO:0016310690.015
negative regulation of programmed cell deathGO:0043069580.015
response to growth factorGO:0070848390.015
regulation of cell activationGO:005086510.015
zymogen activationGO:003163830.015
regulation of response to stimulusGO:00485832690.015
Mouse Worm
skeletal muscle thin filament assemblyGO:003024040.015
regulation of cellular amine metabolic processGO:003323800.015
neuron differentiationGO:00301823530.014
cellular component assemblyGO:00226071700.014
immune system processGO:00023762410.014
defense response to bacteriumGO:0042742220.014
regulation of protein catabolic processGO:004217610.014
embryonic heart tube morphogenesisGO:00031431080.014
cell substrate adhesionGO:003158940.014
response to corticosteroidGO:003196010.014
cellular response to nutrient levelsGO:003166920.014
cell recognitionGO:0008037190.014
regulation of reactive oxygen species metabolic processGO:200037720.014
sensory perception of touchGO:005097520.013
autophagyGO:000691440.013
amine metabolic processGO:000930820.013
regulation of cell shapeGO:000836010.013
cell fate commitment involved in formation of primary germ layerGO:0060795260.013
Worm
regulation of myotube differentiationGO:001083020.013
regulation of body fluid levelsGO:0050878160.013
modification dependent macromolecule catabolic processGO:004363230.013
cell chemotaxisGO:0060326170.013
response to other organismGO:0051707970.013
regulation of epithelial cell proliferationGO:005067830.013
neuron migrationGO:0001764220.013
mesoderm morphogenesisGO:0048332510.013
Worm
keratinocyte differentiationGO:003021600.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
negative regulation of epithelial cell proliferationGO:005068010.013
regulation of organ growthGO:004662030.013
negative regulation of cell deathGO:0060548600.013
centrosome duplicationGO:005129810.012
oxoacid metabolic processGO:0043436310.012
forebrain developmentGO:0030900960.012
peptide transportGO:001583310.012
positive regulation of catabolic processGO:000989640.012
regulation of cell differentiationGO:00455951420.012
developmental growthGO:00485891660.012
Worm
regulation of metal ion transportGO:001095940.012
regulation of localizationGO:00328791040.012
carboxylic acid metabolic processGO:0019752220.012
regulation of endodermal cell fate specificationGO:0042663150.012
regulation of programmed cell deathGO:00430671010.012
regulation of bindingGO:005109830.012
bone remodelingGO:004684920.012
negative regulation of response to stimulusGO:00485851040.012
Mouse
urogenital system developmentGO:0001655970.012
blood vessel endothelial cell migrationGO:0043534180.012
positive regulation of immune effector processGO:000269930.012
lipid storageGO:001991510.012
female sex differentiationGO:004666040.012
odontogenesis of dentin containing toothGO:004247510.012
negative regulation of catabolic processGO:000989530.011
gtp catabolic processGO:000618420.011
protein complex localizationGO:003150310.011
regulation of rna metabolic processGO:00512522240.011
Mouse Worm
production of molecular mediator of immune responseGO:000244020.011
heart contractionGO:0060047710.011
single organism intracellular transportGO:1902582250.011
positive regulation of stress activated mapk cascadeGO:003287430.011
proteasomal protein catabolic processGO:001049820.011
cell proliferation involved in heart morphogenesisGO:006132320.011
neural precursor cell proliferationGO:0061351200.011
positive regulation of striated muscle cell differentiationGO:005115510.011
protein acylationGO:004354330.011
cytokine metabolic processGO:004210710.011
behaviorGO:0007610740.011
regulation of cytokine biosynthetic processGO:004203510.011
cellular response to molecule of bacterial originGO:007121930.011
wound healingGO:0042060900.011
positive regulation of cytokine productionGO:000181920.011
mitotic cell cycleGO:0000278640.011
peptidyl serine phosphorylationGO:001810510.011
connective tissue developmentGO:0061448990.011
primary neural tube formationGO:001402010.011
retina development in camera type eyeGO:00600411460.011
response to glucocorticoidGO:005138410.011
deathGO:00162651210.011
macromolecule modificationGO:00434121110.011
embryonic digestive tract developmentGO:004856640.011
regulation of cellular component organizationGO:0051128860.011
developmental growth involved in morphogenesisGO:0060560860.011
cytoskeleton organizationGO:0007010960.011
cartilage developmentGO:0051216960.011
inner ear receptor cell differentiationGO:0060113290.011
response to biotic stimulusGO:0009607970.011
sequestering of metal ionGO:005123830.011
defense responseGO:0006952470.010
dorsal ventral pattern formationGO:00099531250.010
regulation of cardiac muscle tissue developmentGO:005502410.010
regulation of reproductive processGO:200024140.010
organic acid metabolic processGO:0006082310.010
compound eye developmentGO:004874920.010
neuron developmentGO:00486662620.010
peripheral nervous system neuron differentiationGO:0048934280.010
positive regulation of response to external stimulusGO:003210390.010
regulation of synapse organizationGO:005080730.010
membrane invaginationGO:001032410.010
negative regulation of apoptotic processGO:0043066550.010
regulation of circadian rhythmGO:004275240.010
canonical wnt signaling pathwayGO:0060070480.010

hfe2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.026
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.014
organ system cancerDOID:005068600.011
musculoskeletal system diseaseDOID:1700.011
disease of metabolismDOID:001466700.010