Danio rerio

0 known processes

mll4b

myeloid/lymphoid or mixed-lineage leukemia 4b

mll4b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h4 k20 methylationGO:003477020.970
histone lysine methylationGO:0034968120.871
Mouse Fly
chromatin modificationGO:0016568210.853
Mouse Fly
histone h3 k9 modificationGO:006164750.729
cellular biosynthetic processGO:00442492860.656
Fly
cellular macromolecule metabolic processGO:00442603910.600
Mouse Fly
protein methylationGO:0006479130.555
Mouse Fly
peptidyl lysine trimethylationGO:001802310.454
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.447
Fly
regulation of nitrogen compound metabolic processGO:00511712510.434
Fly
macromolecule methylationGO:0043414190.392
Mouse Fly
biosynthetic processGO:00090582940.385
Fly
methylationGO:0032259220.360
Mouse Fly
histone modificationGO:0016570200.351
Mouse Fly
transcription from rna polymerase ii promoterGO:0006366800.341
Fly
nucleic acid metabolic processGO:00903042440.340
Fly
organic substance biosynthetic processGO:19015762890.338
Fly
single organism metabolic processGO:00447102170.325
Mouse Fly
histone h3 k9 methylationGO:005156750.316
cellular nitrogen compound metabolic processGO:00346412900.310
Fly
nitrogen compound metabolic processGO:00068073190.305
Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.299
Fly
macromolecule biosynthetic processGO:00090592270.274
Fly
peptidyl lysine methylationGO:001802230.263
Mouse
cellular aromatic compound metabolic processGO:00067252950.257
Fly
cellular nitrogen compound biosynthetic processGO:00442712180.251
Fly
regulation of metabolic processGO:00192223590.235
Mouse Fly
erythrocyte homeostasisGO:0034101550.228
Zebrafish
aromatic compound biosynthetic processGO:00194382170.220
Fly
protein alkylationGO:0008213130.212
Mouse Fly
heterocycle biosynthetic processGO:00181302150.211
Fly
regulation of primary metabolic processGO:00800903110.205
Mouse Fly
organic cyclic compound biosynthetic processGO:19013622230.203
Fly
cellular macromolecule biosynthetic processGO:00346452240.197
Fly
myeloid cell homeostasisGO:0002262560.178
Zebrafish
rna metabolic processGO:00160702190.169
Fly
negative regulation of gene expressionGO:0010629650.167
Mouse
organic cyclic compound metabolic processGO:19013603010.166
Fly
regulation of macromolecule biosynthetic processGO:00105562250.164
Fly
chromatin organizationGO:0006325220.164
Mouse Fly
regulation of biosynthetic processGO:00098892500.159
Fly
erythrocyte differentiationGO:0030218540.158
Zebrafish
gene expressionGO:00104672520.155
Mouse Fly
regulation of rna biosynthetic processGO:20011412130.150
Fly
regulation of transcription dna templatedGO:00063552130.132
Fly
regulation of nucleic acid templated transcriptionGO:19035062130.131
Fly
chromosome organizationGO:0051276310.126
Mouse Fly
macromolecular complex subunit organizationGO:0043933740.123
Mouse Fly
rna biosynthetic processGO:00327741810.110
Fly
embryo development ending in birth or egg hatchingGO:00097922710.109
immune system developmentGO:00025201910.109
Zebrafish
agingGO:000756820.103
hematopoietic or lymphoid organ developmentGO:00485341910.099
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.097
Fly
homeostasis of number of cellsGO:0048872620.097
Zebrafish
negative regulation of cellular metabolic processGO:0031324770.093
protein modification processGO:00362111000.093
Mouse Fly
cellular protein modification processGO:00064641000.088
Mouse Fly
negative regulation of macromolecule biosynthetic processGO:0010558480.088
negative regulation of biological processGO:00485193040.082
Mouse
regulation of macromolecule metabolic processGO:00602553170.081
Mouse Fly
histone methylationGO:0016571130.080
Mouse Fly
cellular component movementGO:00069283350.078
Fly
heterocycle metabolic processGO:00464832900.078
Fly
immune system processGO:00023762410.077
Zebrafish
hemopoiesisGO:00300971830.076
Zebrafish
positive regulation of rna metabolic processGO:0051254590.075
Fly
organelle organizationGO:00069962270.072
Mouse Fly
regulation of multicellular organism growthGO:004001440.068
regulation of protein complex assemblyGO:004325430.067
transcription dna templatedGO:00063511810.065
Fly
regulation of rna metabolic processGO:00512522240.065
Fly
multicellular organism growthGO:003526440.064
regulation of cellular metabolic processGO:00313233200.063
Mouse Fly
regulation of multicellular organismal processGO:00512392770.062
reproductive processGO:0022414400.061
Mouse Fly
histone h3 k4 methylationGO:005156820.060
Mouse Fly
negative regulation of cellular processGO:00485232830.058
larval developmentGO:000216420.057
cellular protein metabolic processGO:00442671290.057
Mouse Fly
locomotionGO:00400113130.056
Fly
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.054
Fly
organonitrogen compound metabolic processGO:1901564740.054
histone h3 k36 methylationGO:001045220.052
negative regulation of rna biosynthetic processGO:1902679450.052
multicellular organism reproductionGO:0032504350.051
Mouse Fly
nucleic acid templated transcriptionGO:00976591810.051
Fly
guanosine containing compound catabolic processGO:190106920.051
multicellular organismal reproductive processGO:0048609350.044
Mouse Fly
positive regulation of biosynthetic processGO:0009891680.043
Fly
negative regulation of rna metabolic processGO:0051253480.043
cell motilityGO:00488702440.043
Fly
negative regulation of transcription dna templatedGO:0045892450.040
positive regulation of transcription dna templatedGO:0045893570.040
Fly
peptide transportGO:001583310.039
negative regulation of nucleobase containing compound metabolic processGO:0045934590.039
single organism organelle organizationGO:19025891990.038
Mouse Fly
positive regulation of nucleobase containing compound metabolic processGO:0045935690.038
Fly
nucleobase containing compound metabolic processGO:00061392740.038
Fly
regulation of transcription from rna polymerase ii promoterGO:00063571140.037
Fly
myeloid cell developmentGO:0061515320.037
Zebrafish
internal peptidyl lysine acetylationGO:001839320.037
Fly
myeloid cell differentiationGO:0030099860.037
Zebrafish
negative regulation of kinase activityGO:003367340.036
gtp metabolic processGO:004603940.036
multi organism reproductive processGO:0044703360.036
Mouse Fly
negative regulation of protein serine threonine kinase activityGO:007190120.036
epithelial cell differentiationGO:00308551160.035
positive regulation of cellular metabolic processGO:0031325940.035
Fly
cytokinesisGO:000091030.035
homeostatic processGO:00425921420.033
Zebrafish
localization of cellGO:00516742440.033
Fly
negative regulation of metabolic processGO:0009892860.032
Mouse
female gonad developmentGO:000858540.032
Mouse
negative regulation of nucleocytoplasmic transportGO:004682320.032
neurotransmitter secretionGO:000726920.032
positive regulation of rna biosynthetic processGO:1902680570.032
Fly
negative regulation of small gtpase mediated signal transductionGO:005105810.032
meiotic cell cycle processGO:190304630.032
internal protein amino acid acetylationGO:000647520.032
Fly
programmed cell deathGO:00125011190.031
digestive system developmentGO:00551232890.031
regulation of mrna processingGO:005068430.030
protein demethylationGO:000648220.030
single organism nuclear importGO:190259330.030
developmental process involved in reproductionGO:0003006270.030
Mouse
reproductionGO:0000003400.030
Mouse Fly
negative regulation of protein phosphorylationGO:000193340.029
negative regulation of biosynthetic processGO:0009890550.028
regulation of production of molecular mediator of immune responseGO:000270010.028
protein metabolic processGO:00195381830.028
Mouse Fly
macromolecule modificationGO:00434121110.027
Mouse Fly
regulation of gene expressionGO:00104682650.027
Mouse Fly
positive regulation of exocytosisGO:004592110.026
cell migrationGO:00164772370.026
Fly
positive regulation of gene expressionGO:0010628710.026
Fly
positive regulation of macromolecule metabolic processGO:0010604930.025
Fly
positive regulation of myeloid cell differentiationGO:004563920.025
regulation of establishment of protein localizationGO:007020140.025
positive regulation of biological processGO:00485182530.025
Fly
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.025
stem cell divisionGO:001714510.025
negative regulation of nucleic acid templated transcriptionGO:1903507450.024
negative regulation of protein transportGO:005122430.024
deathGO:00162651210.024
regulation of cellular ketone metabolic processGO:001056570.024
negative regulation of protein complex assemblyGO:003133310.024
multi organism processGO:00517041340.024
Mouse Fly
regulation of alternative mrna splicing via spliceosomeGO:000038110.024
negative regulation of protein kinase activityGO:000646940.023
positive regulation of nitrogen compound metabolic processGO:0051173690.023
Fly
positive regulation of protein polymerizationGO:003227320.023
regulation of biological qualityGO:00650082630.023
Zebrafish
peptidyl lysine dimethylationGO:001802710.023
cell part morphogenesisGO:00329902460.022
Fly
meiotic chromosome segregationGO:004513230.022
sexual reproductionGO:0019953360.022
Mouse Fly
negative regulation of jnk cascadeGO:004632910.022
antimicrobial humoral responseGO:001973020.021
positive regulation of reproductive processGO:200024320.021
meiotic nuclear divisionGO:000712640.021
positive regulation of apoptotic signaling pathwayGO:200123510.021
p38mapk cascadeGO:003806610.021
cellular response to extracellular stimulusGO:003166820.021
positive regulation of cellular catabolic processGO:003133130.021
regulation of protein transportGO:005122330.020
developmental growthGO:00485891660.020
gtp catabolic processGO:000618420.020
phagocytosisGO:000690930.020
positive regulation of cellular biosynthetic processGO:0031328680.020
Fly
gastrulationGO:00073692080.020
dna catabolic processGO:000630810.020
signal transductionGO:00071654550.020
regulation of intracellular protein transportGO:003315730.020
regulation of cellular amino acid metabolic processGO:000652100.020
synaptic vesicle localizationGO:009747910.020
regulation of cell activationGO:005086510.020
negative regulation of defense responseGO:003134820.020
protein acylationGO:004354330.019
Fly
chordate embryonic developmentGO:00430092710.019
production of molecular mediator of immune responseGO:000244020.019
establishment of synaptic vesicle localizationGO:009748010.019
positive regulation of catabolic processGO:000989640.019
endosomal transportGO:001619720.019
positive regulation of cellular processGO:00485222010.018
Fly
actin filament polymerizationGO:003004120.018
neuron projection guidanceGO:0097485860.018
Fly
neuron projection morphogenesisGO:00488121610.018
Fly
regulation of nucleocytoplasmic transportGO:004682220.018
negative regulation of nitrogen compound metabolic processGO:0051172590.018
germ line stem cell divisionGO:004207810.017
regulation of protein polymerizationGO:003227120.017
rna export from nucleusGO:000640510.017
chemotaxisGO:00069351040.017
Fly
neurotransmitter transportGO:000683620.017
neuron developmentGO:00486662620.017
Fly
negative regulation of intracellular transportGO:003238730.017
development of primary female sexual characteristicsGO:004654540.017
Mouse
response to endogenous stimulusGO:0009719830.017
response to biotic stimulusGO:0009607970.017
synaptic vesicle endocytosisGO:004848810.016
nuclear importGO:005117030.016
cell projection morphogenesisGO:00488582440.016
Fly
response to organic substanceGO:00100331530.016
pigmentationGO:0043473850.016
embryonic organ developmentGO:00485683810.016
regulation of histone methylationGO:003106030.016
Mouse
negative regulation of cytoplasmic transportGO:190365020.016
regulation of photoreceptor cell differentiationGO:004653220.016
protein importGO:001703830.016
axon developmentGO:00615641660.016
Fly
amine metabolic processGO:000930820.016
locomotor rhythmGO:004547530.016
negative regulation of macromolecule metabolic processGO:0010605760.015
Mouse
single organism reproductive processGO:0044702400.015
Mouse Fly
regulation of neurotransmitter transportGO:005158810.015
ovulation cycle processGO:002260220.015
Mouse
peptidyl lysine acetylationGO:001839420.015
Fly
muscle cell developmentGO:00550011150.015
regulation of dna recombinationGO:000001820.015
protein complex localizationGO:003150310.015
nucleocytoplasmic transportGO:000691340.015
response to external stimulusGO:00096052640.015
Fly
mitotic cell cycle embryonicGO:004544820.015
apoptotic processGO:00069151160.014
alternative mrna splicing via spliceosomeGO:000038010.014
small molecule metabolic processGO:0044281770.014
regulation of response to stimulusGO:00485832690.014
Fly
protein acetylationGO:000647320.014
Fly
negative regulation of protein import into nucleusGO:004230820.014
growthGO:00400071740.014
negative regulation of mrna metabolic processGO:190331230.014
maintenance of locationGO:005123540.014
establishment of protein localization to organelleGO:007259440.014
regulation of cytoplasmic transportGO:190364940.014
dna templated transcription elongationGO:000635430.014
Fly
positive regulation of protein complex assemblyGO:003133420.013
regulation of gene silencingGO:006096810.013
cellular carbohydrate metabolic processGO:004426240.013
nuclear transportGO:005116940.013
response to chemicalGO:00422213200.013
Fly
ovarian follicle developmentGO:000154120.013
Mouse
positive regulation of dna templated transcription elongationGO:003278610.013
Fly
protein dephosphorylationGO:000647030.013
somatic cell dna recombinationGO:001644410.013
stem cell maintenanceGO:001982740.013
actin cytoskeleton organizationGO:0030036630.013
synaptic vesicle recyclingGO:003646510.013
regulation of neurological system processGO:003164420.013
cell deathGO:00082191210.013
cellular response to starvationGO:000926710.013
protein localization to nucleusGO:003450430.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
positive regulation of jnk cascadeGO:004633030.013
endosome organizationGO:000703220.012
post golgi vesicle mediated transportGO:000689210.012
i kappab kinase nf kappab signalingGO:000724940.012
response to stressGO:00069502630.012
Fly
cellular response to nutrient levelsGO:003166920.012
positive regulation of nucleic acid templated transcriptionGO:1903508570.012
Fly
regulation of organelle assemblyGO:190211540.012
response to corticosteroidGO:003196010.012
cell surface receptor signaling pathwayGO:00071663250.012
vacuolar transportGO:000703420.012
positive regulation of map kinase activityGO:004340630.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
cellular component disassemblyGO:002241110.012
golgi vesicle transportGO:004819330.012
regulation of cellular amine metabolic processGO:003323800.012
tube morphogenesisGO:00352393490.012
regulation of neurotransmitter secretionGO:004692810.012
negative regulation of mapk cascadeGO:004340940.012
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.012
Fly
negative regulation of rna splicingGO:003311910.012
negative regulation of mrna splicing via spliceosomeGO:004802510.012
regulation of exocytosisGO:001715710.012
positive regulation of cell activationGO:005086710.012
regulation of cell projection assemblyGO:006049140.012
cell morphogenesisGO:00009022890.012
Fly
stem cell fate commitmentGO:004886510.012
lipid storageGO:001991510.011
carboxylic acid metabolic processGO:0019752220.011
gamete generationGO:0007276330.011
Mouse Fly
insulin like growth factor receptor signaling pathwayGO:004800940.011
cellular ketone metabolic processGO:0042180110.011
cell cycle g2 m phase transitionGO:004483940.011
outflow tract morphogenesisGO:000315110.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
Fly
negative regulation of intracellular protein transportGO:009031730.011
central nervous system developmentGO:00074173870.011
lysosomal transportGO:000704120.011
rna transportGO:005065820.011
regulation of erythrocyte differentiationGO:004564620.011
negative regulation of cytokine productionGO:000181810.011
somatic muscle developmentGO:000752540.011
covalent chromatin modificationGO:0016569200.011
Mouse Fly
cell cycle g1 s phase transitionGO:004484310.011
autophagyGO:000691440.011
monocyte differentiationGO:003022420.011
regulation of cellular response to growth factor stimulusGO:0090287350.011
exocytosisGO:000688710.011
regulation of p38mapk cascadeGO:190074410.011
negative regulation of cell communicationGO:0010648960.011
negative regulation of dna metabolic processGO:005105340.011
regulation of nucleotide catabolic processGO:003081120.011
cellular response to external stimulusGO:007149620.011
positive regulation of leukocyte differentiationGO:190210710.011
hatchingGO:003518840.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
Fly
negative regulation of histone modificationGO:003105710.011
response to carbohydrateGO:000974330.011
positive regulation of secretion by cellGO:190353210.011
cartilage developmentGO:0051216960.010
cellular response to organic cyclic compoundGO:0071407380.010
positive regulation of epithelial cell differentiationGO:003085820.010
establishment of protein localization to vacuoleGO:007266610.010
determination of left right symmetryGO:00073681790.010
negative regulation of protein localization to nucleusGO:190018120.010
small molecule catabolic processGO:004428230.010
nucleic acid transportGO:005065720.010
photoreceptor cell morphogenesisGO:000859410.010
protein secretionGO:000930610.010
g1 s transition of mitotic cell cycleGO:000008210.010
positive regulation of metabolic processGO:00098931080.010
Fly
positive regulation of multi organism processGO:004390230.010
positive regulation of immune effector processGO:000269930.010
female gamete generationGO:0007292140.010
Mouse
protein targeting to nucleusGO:004474430.010

mll4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
disease of anatomical entityDOID:700.012
organ system cancerDOID:005068600.012
musculoskeletal system diseaseDOID:1700.010