Danio rerio

0 known processes

chic2

cysteine-rich hydrophobic domain 2

(Aliases: MGC55670,zgc:55670)

chic2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein k48 linked ubiquitinationGO:007093610.164
larval developmentGO:000216420.145
cellular macromolecule metabolic processGO:00442603910.120
modification dependent protein catabolic processGO:001994130.106
macromolecule modificationGO:00434121110.104
ubiquitin dependent protein catabolic processGO:000651130.103
positive regulation of transportGO:005105020.096
proteolysis involved in cellular protein catabolic processGO:005160330.094
negative regulation of cellular processGO:00485232830.085
cortical actin cytoskeleton organizationGO:003086610.080
establishment of protein localization to organelleGO:007259440.077
protein modification processGO:00362111000.076
stem cell proliferationGO:007208940.075
protein polyubiquitinationGO:000020940.070
cellular protein modification processGO:00064641000.066
signal transductionGO:00071654550.064
protein acylationGO:004354330.061
peptidyl lysine acetylationGO:001839420.060
protein metabolic processGO:00195381830.059
regulation of cellular metabolic processGO:00313233200.058
cellular biosynthetic processGO:00442492860.057
protein dephosphorylationGO:000647030.056
biosynthetic processGO:00090582940.054
neuron differentiationGO:00301823530.053
cellular protein metabolic processGO:00442671290.053
agingGO:000756820.052
negative regulation of protein phosphorylationGO:000193340.051
negative regulation of protein kinase activityGO:000646940.049
cellular nitrogen compound metabolic processGO:00346412900.049
cell projection organizationGO:00300302840.049
nucleocytoplasmic transportGO:000691340.048
negative regulation of biological processGO:00485193040.048
regulation of response to stimulusGO:00485832690.047
regulation of macromolecule metabolic processGO:00602553170.046
regulation of cell communicationGO:00106462320.045
nuclear transportGO:005116940.044
cortical cytoskeleton organizationGO:003086510.043
single organism organelle organizationGO:19025891990.043
heterocycle metabolic processGO:00464832900.043
protein targeting to nucleusGO:004474430.042
protein import into nucleusGO:000660630.042
modification dependent macromolecule catabolic processGO:004363230.042
immune system processGO:00023762410.042
regulation of developmental processGO:00507932470.041
internal protein amino acid acetylationGO:000647520.041
meiotic nuclear divisionGO:000712640.041
nuclear importGO:005117030.040
nucleic acid metabolic processGO:00903042440.039
positive regulation of cellular processGO:00485222010.039
single organism nuclear importGO:190259330.038
adult behaviorGO:003053420.038
regulation of multicellular organismal developmentGO:20000262230.038
vasculature developmentGO:00019442780.038
nitrogen compound metabolic processGO:00068073190.038
regulation of primary metabolic processGO:00800903110.036
protein localization to nucleusGO:003450430.036
single organism metabolic processGO:00447102170.036
protein acetylationGO:000647320.036
organic cyclic compound biosynthetic processGO:19013622230.035
regulation of cytoplasmic transportGO:190364940.035
regulation of i kappab kinase nf kappab signalingGO:004312240.035
cellular component movementGO:00069283350.035
regulation of metabolic processGO:00192223590.035
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.034
nucleobase containing compound biosynthetic processGO:00346542050.034
organic substance biosynthetic processGO:19015762890.034
regulation of protein import into nucleusGO:004230620.034
positive regulation of stress activated mapk cascadeGO:003287430.034
response to stressGO:00069502630.033
nucleobase containing compound metabolic processGO:00061392740.033
regulation of multicellular organismal processGO:00512392770.033
cellular macromolecule biosynthetic processGO:00346452240.033
macromolecule biosynthetic processGO:00090592270.033
g1 s transition of mitotic cell cycleGO:000008210.032
specification of symmetryGO:00097992040.032
regulation of protein targetingGO:190353320.032
peptidyl serine phosphorylationGO:001810510.032
negative regulation of map kinase activityGO:004340720.032
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.032
post golgi vesicle mediated transportGO:000689210.031
peptidyl serine modificationGO:001820920.031
gene expressionGO:00104672520.031
negative regulation of signal transductionGO:0009968940.031
regulation of multicellular organism growthGO:004001440.031
negative regulation of mapk cascadeGO:004340940.031
positive regulation of jnk cascadeGO:004633030.031
i kappab kinase nf kappab signalingGO:000724940.031
regulation of cell projection assemblyGO:006049140.031
regulation of organelle assemblyGO:190211540.031
regulation of protein transportGO:005122330.031
cellular aromatic compound metabolic processGO:00067252950.031
protein localization to plasma membraneGO:007265910.030
neuron developmentGO:00486662620.030
regulation of circadian rhythmGO:004275240.030
cell migrationGO:00164772370.030
angiogenesisGO:00015251580.029
immune system developmentGO:00025201910.029
proteasomal protein catabolic processGO:001049820.029
regulation of establishment of protein localizationGO:007020140.029
golgi vesicle transportGO:004819330.028
regulation of biosynthetic processGO:00098892500.028
cognitionGO:005089010.028
phagocytosisGO:000690930.028
protein importGO:001703830.028
phosphate containing compound metabolic processGO:00067961080.028
regulation of protein catabolic processGO:004217610.028
regulation of stem cell proliferationGO:007209120.027
regulation of signalingGO:00230512350.027
generation of neuronsGO:00486993850.027
membrane fusionGO:006102520.027
positive regulation of cellular component biogenesisGO:004408930.027
single organism membrane fusionGO:004480120.026
negative regulation of protein serine threonine kinase activityGO:007190120.026
rna localizationGO:000640340.026
response to drugGO:004249330.026
positive regulation of biological processGO:00485182530.025
locomotor rhythmGO:004547530.025
lateral inhibitionGO:004633110.025
system processGO:00030081850.025
regulation of cell differentiationGO:00455951420.025
negative regulation of kinase activityGO:003367340.025
regulation of reproductive processGO:200024140.025
positive regulation of catabolic processGO:000989640.025
phosphorus metabolic processGO:00067931090.025
regulation of intracellular protein transportGO:003315730.025
regulation of synaptic plasticityGO:004816710.025
autophagyGO:000691440.025
regulation of nitrogen compound metabolic processGO:00511712510.024
regulation of rna metabolic processGO:00512522240.024
regulation of cellular amino acid metabolic processGO:000652100.024
regulation of transcription dna templatedGO:00063552130.024
g2 dna damage checkpointGO:003157230.024
cell cycle g1 s phase transitionGO:004484310.024
organic cyclic compound metabolic processGO:19013603010.024
negative regulation of response to stimulusGO:00485851040.024
catecholamine metabolic processGO:000658420.024
multicellular organism growthGO:003526440.024
regulation of filopodium assemblyGO:005148920.023
neurotransmitter secretionGO:000726920.023
regulation of cellular amine metabolic processGO:003323800.023
apoptotic processGO:00069151160.023
mitochondrion organizationGO:000700540.023
determination of left right symmetryGO:00073681790.023
cellular nitrogen compound biosynthetic processGO:00442712180.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
positive regulation of map kinase activityGO:004340630.023
regulation of rna biosynthetic processGO:20011412130.023
regulation of macromolecule biosynthetic processGO:00105562250.023
regulation of nucleocytoplasmic transportGO:004682220.023
negative regulation of metabolic processGO:0009892860.022
positive regulation of canonical wnt signaling pathwayGO:009026340.022
tube morphogenesisGO:00352393490.022
negative regulation of cell deathGO:0060548600.022
transcription dna templatedGO:00063511810.022
internal peptidyl lysine acetylationGO:001839320.022
determination of bilateral symmetryGO:00098552040.021
dna templated transcription elongationGO:000635430.021
endosomal transportGO:001619720.021
regulation of cell shapeGO:000836010.021
membrane invaginationGO:001032410.021
regulation of cell developmentGO:00602841000.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
rna biosynthetic processGO:00327741810.021
amine metabolic processGO:000930820.021
regulation of synapse assemblyGO:005196330.021
blood vessel developmentGO:00015682460.021
cellular response to chemical stimulusGO:00708871570.021
cytoplasm organizationGO:000702840.021
regulation of nervous system developmentGO:0051960900.021
negative regulation of signalingGO:0023057960.021
positive regulation of i kappab kinase nf kappab signalingGO:004312330.021
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
muscle structure developmentGO:00610611960.020
regulation of neurogenesisGO:0050767870.020
guanosine containing compound catabolic processGO:190106920.020
cellular amine metabolic processGO:004410620.020
synaptic vesicle localizationGO:009747910.020
eye developmentGO:00016542770.020
deathGO:00162651210.020
signal transduction by p53 class mediatorGO:0072331130.020
intracellular signal transductionGO:0035556850.020
phosphorylationGO:0016310690.020
regulation of cell deathGO:00109411030.020
negative regulation of cellular metabolic processGO:0031324770.020
positive regulation of protein complex assemblyGO:003133420.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.020
regulation of protein localization to nucleusGO:190018020.019
neuron projection developmentGO:00311751800.019
cell surface receptor signaling pathwayGO:00071663250.019
positive regulation of cytoskeleton organizationGO:005149530.019
cell deathGO:00082191210.019
cellular ketone metabolic processGO:0042180110.019
neurotransmitter transportGO:000683620.019
regulation of receptor mediated endocytosisGO:004825940.019
negative regulation of macromolecule metabolic processGO:0010605760.019
regulation of cellular ketone metabolic processGO:001056570.019
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.019
localization of cellGO:00516742440.019
maintenance of locationGO:005123540.019
rna metabolic processGO:00160702190.019
protein stabilizationGO:005082120.019
regulation of cellular macromolecule biosynthetic processGO:20001122220.019
cellular component morphogenesisGO:00329893360.019
response to chemicalGO:00422213200.019
negative regulation of cytoplasmic transportGO:190365020.018
regulation of biological qualityGO:00650082630.018
guanosine containing compound metabolic processGO:190106840.018
regulation of signal transductionGO:00099662250.018
negative regulation of protein transportGO:005122430.018
establishment of protein localization to plasma membraneGO:009000210.018
determination of heart left right asymmetryGO:00613711170.018
response to organic substanceGO:00100331530.018
regulation of cell activationGO:005086510.018
exocytosisGO:000688710.018
cellular protein catabolic processGO:004425740.018
regulation of cellular protein catabolic processGO:190336210.018
negative regulation of synapse assemblyGO:005196420.018
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225350.018
sensory organ developmentGO:00074233930.018
cellular component assemblyGO:00226071700.018
developmental programmed cell deathGO:001062340.017
organelle fusionGO:004828430.017
regulation of gene expressionGO:00104682650.017
regulation of synapse organizationGO:005080730.017
gtp catabolic processGO:000618420.017
regulation of cellular component movementGO:0051270550.017
regulation of cellular biosynthetic processGO:00313262450.017
wnt signaling pathwayGO:0016055800.017
organelle organizationGO:00069962270.017
nucleic acid templated transcriptionGO:00976591810.017
meiotic cell cycle processGO:190304630.017
negative regulation of nucleocytoplasmic transportGO:004682320.017
programmed cell deathGO:00125011190.017
cell agingGO:000756920.017
synaptic growth at neuromuscular junctionGO:005112420.017
phagosome maturationGO:009038210.017
aromatic compound biosynthetic processGO:00194382170.017
establishment of synaptic vesicle localizationGO:009748010.017
cellular response to lipopolysaccharideGO:007122230.017
cellular response to radiationGO:007147840.017
phagocytosis engulfmentGO:000691110.017
response to hydrogen peroxideGO:004254230.016
regulation of localizationGO:00328791040.016
growthGO:00400071740.016
embryonic organ developmentGO:00485683810.016
muscle cell differentiationGO:00426921390.016
cytokinesisGO:000091030.016
gtp metabolic processGO:004603940.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
cell motilityGO:00488702440.016
lipid storageGO:001991510.016
heart developmentGO:00075073130.016
nuclear exportGO:005116810.016
negative regulation of apoptotic processGO:0043066550.016
regulation of intracellular signal transductionGO:1902531570.016
single organism transportGO:00447652060.016
neuroblast proliferationGO:000740520.016
regulation of dna templated transcription elongationGO:003278430.016
cellular response to extracellular stimulusGO:003166820.016
negative regulation of biosynthetic processGO:0009890550.016
striated muscle cell developmentGO:00550021080.016
acylglycerol homeostasisGO:005509020.016
digestive tract developmentGO:00485652650.016
negative regulation of gliogenesisGO:001401410.016
negative regulation of intracellular protein transportGO:009031730.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
macroautophagyGO:001623610.015
positive regulation of striated muscle tissue developmentGO:004584410.015
response to ketoneGO:190165410.015
ameboidal type cell migrationGO:00016671430.015
heart loopingGO:0001947940.015
cellular amino acid metabolic processGO:000652070.015
hemopoiesisGO:00300971830.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
regulation of growth rateGO:004000910.015
developmental growthGO:00485891660.015
entrainment of circadian clockGO:000964920.015
chemosensory behaviorGO:000763510.015
vacuolar transportGO:000703420.015
camera type eye developmentGO:00430102220.015
response to uvGO:000941130.015
regulation of apoptotic processGO:0042981980.015
regulation of skeletal muscle tissue developmentGO:004864140.015
centrosome cycleGO:000709810.015
endosome organizationGO:000703220.015
regulation of organ growthGO:004662030.015
regulation of protein ubiquitinationGO:003139630.015
negative regulation of protein localization to nucleusGO:190018120.015
germ line stem cell maintenanceGO:003071820.015
negative regulation of cell communicationGO:0010648960.015
glial cell proliferationGO:001400940.015
morphogenesis of an epitheliumGO:00020093330.015
mitotic cell cycleGO:0000278640.015
peptide transportGO:001583310.015
proteolysisGO:0006508380.015
positive regulation of cell cycleGO:004578730.014
synaptic vesicle recyclingGO:003646510.014
negative regulation of programmed cell deathGO:0043069580.014
regulation of bindingGO:005109830.014
regulation of purine nucleotide catabolic processGO:003312120.014
regulation of establishment or maintenance of cell polarityGO:003287820.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
activation of mapk activityGO:000018730.014
apoptotic process involved in developmentGO:190274220.014
transcription elongation from rna polymerase ii promoterGO:000636830.014
regulation of epithelial cell proliferationGO:005067830.014
cellular response to organic substanceGO:00713101050.014
positive regulation of cellular biosynthetic processGO:0031328680.014
negative regulation of intracellular transportGO:003238730.014
muscle cell migrationGO:001481240.014
regulation of protein complex assemblyGO:004325430.014
sleepGO:003043110.014
oxoacid metabolic processGO:0043436310.014
meiosis iGO:000712710.014
positive regulation of stem cell proliferationGO:200064810.014
female sex differentiationGO:004666040.014
regulation of programmed cell deathGO:00430671010.013
negative regulation of reproductive processGO:200024230.013
cell morphogenesisGO:00009022890.013
cell cycleGO:0007049930.013
locomotionGO:00400113130.013
regulation of dendrite developmentGO:005077330.013
synaptic vesicle transportGO:004848910.013
pancreas developmentGO:0031016840.013
regulation of cytokine productionGO:000181730.013
establishment of protein localization to vacuoleGO:007266610.013
positive regulation of cellular catabolic processGO:003133130.013
camera type eye morphogenesisGO:00485931080.013
response to external stimulusGO:00096052640.013
cell projection morphogenesisGO:00488582440.013
embryonic limb morphogenesisGO:003032620.013
organonitrogen compound metabolic processGO:1901564740.013
golgi organizationGO:000703010.013
carboxylic acid metabolic processGO:0019752220.013
blood vessel morphogenesisGO:00485142160.013
compound eye developmentGO:004874920.013
regulation of reactive oxygen species metabolic processGO:200037720.013
cellular response to biotic stimulusGO:007121630.012
eye morphogenesisGO:00485921440.012
double strand break repair via homologous recombinationGO:000072410.012
actin polymerization or depolymerizationGO:000815420.012
regulation of protein metabolic processGO:0051246560.012
regulation of response to cytokine stimulusGO:006075930.012
negative regulation of gene expressionGO:0010629650.012
circadian sleep wake cycle sleepGO:005080210.012
triglyceride homeostasisGO:007032820.012
circadian sleep wake cycleGO:004274520.012
negative regulation of cellular catabolic processGO:003133030.012
regulation of wnt signaling pathwayGO:0030111530.012
cellular response to external stimulusGO:007149620.012
positive regulation of immune effector processGO:000269930.012
cellular response to starvationGO:000926710.012
negative regulation of intracellular signal transductionGO:1902532220.012
sequestering of calcium ionGO:005120830.012
brain developmentGO:00074202930.012
positive regulation of biosynthetic processGO:0009891680.012
central nervous system developmentGO:00074173870.012
dicarboxylic acid transportGO:000683510.012
odontogenesis of dentin containing toothGO:004247510.012
negative regulation of tor signalingGO:003200720.012
cellular response to light stimulusGO:007148240.012
negative regulation of protein import into nucleusGO:004230820.012
cellular response to molecule of bacterial originGO:007121930.012
post embryonic organ developmentGO:004856940.012
negative regulation of i kappab kinase nf kappab signalingGO:004312410.012
double strand break repairGO:000630230.012
negative regulation of cell migrationGO:0030336170.012
negative regulation of catabolic processGO:000989530.012
mitotic dna integrity checkpointGO:004477440.012
lipid metabolic processGO:0006629520.012
positive regulation of cellular metabolic processGO:0031325940.012
negative regulation of signal transduction by p53 class mediatorGO:190179780.012
antimicrobial humoral responseGO:001973020.012
digestive system developmentGO:00551232890.012
regulation of response to biotic stimulusGO:000283120.012
b cell activationGO:004211320.012
centrosome organizationGO:005129710.012
female gonad developmentGO:000858540.012
positive regulation of cytokine productionGO:000181920.012
positive regulation of secretion by cellGO:190353210.012
regulation of neuronal synaptic plasticityGO:004816810.011
recombinational repairGO:000072510.011
rna transportGO:005065820.011
regulation of cell migrationGO:0030334400.011
negative regulation of multi organism processGO:004390130.011
chromosome organization involved in meiosisGO:007019210.011
positive regulation of secretionGO:005104710.011
regulation of carbohydrate metabolic processGO:000610940.011
muscle cell developmentGO:00550011150.011
protein secretionGO:000930610.011
cellular response to nutrient levelsGO:003166920.011
axon developmentGO:00615641660.011
extrinsic apoptotic signaling pathwayGO:009719130.011
production of molecular mediator of immune responseGO:000244020.011
circadian sleep wake cycle processGO:002241020.011
histone h3 k4 methylationGO:005156820.011
transcription from rna polymerase ii promoterGO:0006366800.011
positive regulation of gtpase activityGO:004354710.011
lipid homeostasisGO:005508830.011
heterocycle biosynthetic processGO:00181302150.011
organic acid metabolic processGO:0006082310.011
regulation of erk1 and erk2 cascadeGO:007037240.011
female meiotic divisionGO:000714320.011
protein homooligomerizationGO:005126030.011
neuron projection morphogenesisGO:00488121610.011
intracellular mrna localizationGO:000829810.011
cell part morphogenesisGO:00329902460.011
mitotic cell cycle processGO:1903047480.011
regulation of gtpase activityGO:004308720.011
regulation of embryonic developmentGO:0045995470.011
regulation of blood vessel sizeGO:005088020.011
gastrulationGO:00073692080.011
somatic stem cell maintenanceGO:003501910.011
stem cell maintenanceGO:001982740.011
positive regulation of cell adhesionGO:004578510.011
regulation of circadian sleep wake cycleGO:004274910.011
glycerolipid biosynthetic processGO:004501710.011
regulation of protein bindingGO:004339330.011
cell substrate adhesionGO:003158940.011
actin filament polymerizationGO:003004120.011
development of primary female sexual characteristicsGO:004654540.011
regulation of cellular phGO:003064110.011
regulation of jak stat cascadeGO:004642530.010
single organism localizationGO:19025782250.010
regulation of tube sizeGO:003515020.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
cell cycle processGO:0022402530.010
regulation of protein polymerizationGO:003227120.010
protein targeting to vacuoleGO:000662310.010
regulation of neurotransmitter secretionGO:004692810.010
regulation of neuron differentiationGO:0045664560.010
regulation of dendrite morphogenesisGO:004881430.010
embryo development ending in birth or egg hatchingGO:00097922710.010
response to woundingGO:00096111160.010
synaptic vesicle endocytosisGO:004848810.010
regulation of lipid transportGO:003236840.010
regulation of photoreceptor cell differentiationGO:004653220.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.010
cellular amide metabolic processGO:004360340.010
neuron remodelingGO:001632210.010
mitochondrial transportGO:000683920.010
embryonic organ morphogenesisGO:00485622740.010
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.010
cellular response to stressGO:0033554620.010
positive regulation of dna metabolic processGO:005105410.010

chic2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
disease of metabolismDOID:001466700.016
musculoskeletal system diseaseDOID:1700.014
myopathyDOID:42300.014
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.014
nervous system diseaseDOID:86300.014