Danio rerio

0 known processes

ighm

immunoglobulin heavy constant mu and immunoglobulin heavy constant mu

(Aliases: wu:fj14a08,zgc:101769,MGC191870,ighm1)

ighm biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
activation of immune responseGO:000225390.640
aromatic compound biosynthetic processGO:00194382170.629
transcription dna templatedGO:00063511810.526
regulation of metabolic processGO:00192223590.490
cellular nitrogen compound metabolic processGO:00346412900.465
immune response activating signal transductionGO:000275750.461
positive regulation of cellular processGO:00485222010.409
regulation of cellular metabolic processGO:00313233200.403
regulation of macromolecule biosynthetic processGO:00105562250.388
gene expressionGO:00104672520.368
heterocycle metabolic processGO:00464832900.363
peptidyl tyrosine phosphorylationGO:001810850.326
regulation of primary metabolic processGO:00800903110.325
regulation of cellular macromolecule biosynthetic processGO:20001122220.317
cellular macromolecule biosynthetic processGO:00346452240.306
defense responseGO:0006952470.302
amine metabolic processGO:000930820.285
cellular aromatic compound metabolic processGO:00067252950.284
positive regulation of cell activationGO:005086710.275
macromolecule biosynthetic processGO:00090592270.273
positive regulation of cellular amine metabolic processGO:003324000.272
cellular ketone metabolic processGO:0042180110.266
positive regulation of biological processGO:00485182530.249
hematopoietic or lymphoid organ developmentGO:00485341910.248
immune system developmentGO:00025201910.243
regulation of nucleobase containing compound metabolic processGO:00192192500.240
rna metabolic processGO:00160702190.227
regulation of cytokine productionGO:000181730.226
organic cyclic compound biosynthetic processGO:19013622230.220
biosynthetic processGO:00090582940.208
immune system processGO:00023762410.208
t cell activationGO:004211060.201
regulation of leukocyte differentiationGO:190210550.189
compound eye developmentGO:004874920.188
nitrogen compound metabolic processGO:00068073190.178
maintenance of locationGO:005123540.170
single organism metabolic processGO:00447102170.168
nucleic acid metabolic processGO:00903042440.168
regulation of macromolecule metabolic processGO:00602553170.167
defense response to other organismGO:0098542330.146
regulation of immune system processGO:0002682340.140
cellular amine metabolic processGO:004410620.137
positive regulation of cellular amino acid metabolic processGO:004576400.136
positive regulation of protein kinase b signalingGO:005189710.134
response to other organismGO:0051707970.130
regulation of catalytic activityGO:0050790550.127
mononuclear cell proliferationGO:003294310.126
multi organism processGO:00517041340.123
cellular nitrogen compound biosynthetic processGO:00442712180.123
regulation of inflammatory responseGO:005072720.119
divalent inorganic cation homeostasisGO:0072507220.119
regulation of multicellular organismal processGO:00512392770.117
leukocyte differentiationGO:0002521250.117
signal transductionGO:00071654550.114
regulation of cellular biosynthetic processGO:00313262450.113
leukocyte activationGO:0045321120.111
heterocycle biosynthetic processGO:00181302150.111
positive regulation of cellular metabolic processGO:0031325940.110
nucleic acid templated transcriptionGO:00976591810.108
regulation of nitrogen compound metabolic processGO:00511712510.106
positive regulation of secretion by cellGO:190353210.103
organic substance biosynthetic processGO:19015762890.101
regulation of transcription dna templatedGO:00063552130.098
response to external biotic stimulusGO:0043207970.098
activation of innate immune responseGO:000221860.096
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.094
phosphorus metabolic processGO:00067931090.091
regulation of developmental processGO:00507932470.091
hemopoiesisGO:00300971830.089
regulation of gene expressionGO:00104682650.088
phosphorylationGO:0016310690.083
cellular response to external stimulusGO:007149620.081
regulation of biosynthetic processGO:00098892500.078
positive regulation of stress activated mapk cascadeGO:003287430.077
response to biotic stimulusGO:0009607970.075
regulation of molecular functionGO:0065009700.075
regulation of cellular ketone metabolic processGO:001056570.074
immune responseGO:0006955280.074
response to bacteriumGO:0009617580.074
response to stressGO:00069502630.073
leukocyte proliferationGO:007066110.073
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.073
epidermis developmentGO:0008544480.072
homeostatic processGO:00425921420.071
organic cyclic compound metabolic processGO:19013603010.071
cellular macromolecule metabolic processGO:00442603910.069
cell proliferationGO:0008283800.065
regulation of skeletal muscle fiber developmentGO:004874220.065
peptidyl tyrosine modificationGO:001821250.065
cellular protein metabolic processGO:00442671290.064
regulation of cellular amine metabolic processGO:003323800.063
nucleobase containing compound metabolic processGO:00061392740.063
sequestering of calcium ionGO:005120830.062
regulation of peptidyl tyrosine phosphorylationGO:005073010.062
cation homeostasisGO:0055080330.060
cognitionGO:005089010.060
leukocyte homeostasisGO:000177620.060
regulation of actin filament based processGO:003297090.060
negative regulation of cytokine productionGO:000181810.060
positive regulation of metabolic processGO:00098931080.057
regulation of signal transductionGO:00099662250.054
positive regulation of cytosolic calcium ion concentrationGO:000720440.054
regulation of multicellular organism growthGO:004001440.053
protein metabolic processGO:00195381830.052
regulation of protein transportGO:005122330.052
agingGO:000756820.052
positive regulation of signal transductionGO:0009967560.052
symbiosis encompassing mutualism through parasitismGO:004440340.051
larval developmentGO:000216420.051
regulation of biological qualityGO:00650082630.051
macromolecule modificationGO:00434121110.051
regulation of cell differentiationGO:00455951420.050
protein secretionGO:000930610.049
regulation of cellular amino acid metabolic processGO:000652100.049
defense response to fungusGO:005083220.049
negative regulation of defense responseGO:003134820.049
nucleobase containing compound biosynthetic processGO:00346542050.048
carbon dioxide transportGO:001567030.048
regulation of rna biosynthetic processGO:20011412130.048
cell surface receptor signaling pathwayGO:00071663250.047
regulation of cell motilityGO:2000145460.047
negative regulation of multicellular organismal processGO:0051241690.046
positive regulation of transportGO:005105020.046
regulation of response to stimulusGO:00485832690.046
peptide metabolic processGO:000651810.046
positive regulation of nitrogen compound metabolic processGO:0051173690.046
locomotionGO:00400113130.045
cellular biosynthetic processGO:00442492860.045
cytosolic calcium ion transportGO:006040130.045
zymogen activationGO:003163830.045
regulation of cysteine type endopeptidase activityGO:2000116210.044
response to woundingGO:00096111160.044
regulation of rna metabolic processGO:00512522240.044
generation of neuronsGO:00486993850.044
lymphocyte homeostasisGO:000226010.044
regulation of cell activationGO:005086510.043
phosphate containing compound metabolic processGO:00067961080.042
regulation of innate immune responseGO:0045088110.042
calcium ion transport into cytosolGO:006040230.042
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.042
long chain fatty acid biosynthetic processGO:004275910.041
system processGO:00030081850.040
response to chemicalGO:00422213200.039
single organism transportGO:00447652060.039
determination of heart left right asymmetryGO:00613711170.039
regulation of skeletal muscle tissue developmentGO:004864140.039
regulation of tyrosine phosphorylation of stat proteinGO:004250910.039
regulation of phosphorus metabolic processGO:0051174430.039
striated muscle tissue developmentGO:00147061100.039
growthGO:00400071740.038
establishment of localizationGO:00512342440.038
gland developmentGO:00487321430.038
regulation of immune responseGO:0050776140.038
positive regulation of rna biosynthetic processGO:1902680570.037
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.037
b cell mediated immunityGO:001972430.037
protein modification processGO:00362111000.037
carboxylic acid metabolic processGO:0019752220.037
intracellular signal transductionGO:0035556850.036
rna biosynthetic processGO:00327741810.036
negative regulation of growth rateGO:004596710.036
t cell differentiation in thymusGO:003307760.036
exocrine system developmentGO:0035272280.036
nucleotide biosynthetic processGO:0009165210.035
complement activationGO:000695630.035
adherens junction organizationGO:003433240.035
response to organic substanceGO:00100331530.035
immune response regulating signaling pathwayGO:000276450.035
cellular component movementGO:00069283350.035
specification of symmetryGO:00097992040.034
cell substrate adhesionGO:003158940.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.034
regulation of cell communicationGO:00106462320.033
embryonic organ morphogenesisGO:00485622740.033
oxoacid metabolic processGO:0043436310.033
actin filament organizationGO:0007015150.033
positive regulation of secretionGO:005104710.033
organonitrogen compound biosynthetic processGO:1901566470.032
negative regulation of biological processGO:00485193040.032
regulation of protein modification processGO:0031399290.032
regulation of establishment of protein localizationGO:007020140.032
localization of cellGO:00516742440.031
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.031
adaptive immune responseGO:000225050.031
response to nutrientGO:000758430.031
response to vitaminGO:003327330.030
wnt signaling pathwayGO:0016055800.030
positive regulation of lymphocyte mediated immunityGO:000270810.030
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.030
regulation of protein ubiquitinationGO:003139630.029
b cell activationGO:004211320.029
regulation of wound healingGO:006104120.029
lymphocyte proliferationGO:004665110.029
regulation of signalingGO:00230512350.029
positive regulation of cell deathGO:0010942290.029
regulation of protein metabolic processGO:0051246560.029
small molecule metabolic processGO:0044281770.029
positive regulation of erk1 and erk2 cascadeGO:007037420.028
cell projection organizationGO:00300302840.028
response to lipidGO:0033993600.028
positive regulation of response to stimulusGO:0048584800.028
cell migrationGO:00164772370.028
rho protein signal transductionGO:000726650.028
brain developmentGO:00074202930.027
positive regulation of macromolecule metabolic processGO:0010604930.027
i kappab kinase nf kappab signalingGO:000724940.027
actin filament bundle organizationGO:006157260.027
cytoskeleton organizationGO:0007010960.027
interferon beta productionGO:003260810.027
positive regulation of apoptotic signaling pathwayGO:200123510.027
single organism localizationGO:19025782250.027
immunoglobulin mediated immune responseGO:001606430.026
phagocytosisGO:000690930.026
regulation of localizationGO:00328791040.026
cellular component morphogenesisGO:00329893360.026
thymus developmentGO:0048538100.026
positive regulation of stem cell proliferationGO:200064810.026
lymphocyte differentiationGO:003009890.026
positive regulation of cell communicationGO:0010647560.025
organonitrogen compound metabolic processGO:1901564740.025
neuron developmentGO:00486662620.025
cellular protein modification processGO:00064641000.025
developmental growthGO:00485891660.024
positive regulation of phosphorus metabolic processGO:0010562210.024
myeloid cell differentiationGO:0030099860.024
reactive oxygen species metabolic processGO:007259360.024
positive regulation of purine nucleotide biosynthetic processGO:190037380.024
muscle organ developmentGO:00075171010.023
neuroblast fate commitmentGO:001401710.023
neuron projection developmentGO:00311751800.023
multicellular organism growthGO:003526440.023
erythrocyte maturationGO:004324980.023
tyrosine phosphorylation of stat proteinGO:000726010.023
response to lipopolysaccharideGO:0032496130.023
positive regulation of macromolecule biosynthetic processGO:0010557590.022
regulation of phosphorylationGO:0042325260.022
cell fate commitmentGO:0045165990.022
divalent metal ion transportGO:0070838200.022
embryonic organ developmentGO:00485683810.022
astrocyte differentiationGO:004870810.022
regulation of catenin import into nucleusGO:003541220.022
regulation of cellular protein metabolic processGO:0032268520.021
head developmentGO:00603223030.021
negative regulation of muscle tissue developmentGO:190186220.021
central nervous system developmentGO:00074173870.021
cell projection morphogenesisGO:00488582440.021
cell cycle g2 m phase transitionGO:004483940.021
dna biosynthetic processGO:007189730.021
cellular component assemblyGO:00226071700.021
regulation of erk1 and erk2 cascadeGO:007037240.021
spermatid developmentGO:000728620.021
cyclic nucleotide biosynthetic processGO:0009190180.021
morphogenesis of an epitheliumGO:00020093330.021
positive regulation of wound healingGO:009030310.021
regulation of protein localization to nucleusGO:190018020.021
cell morphogenesisGO:00009022890.021
positive regulation of cellular protein metabolic processGO:0032270220.021
tube morphogenesisGO:00352393490.020
positive regulation of jak stat cascadeGO:004642720.020
positive regulation of cellular biosynthetic processGO:0031328680.020
dicarboxylic acid transportGO:000683510.020
regulation of defense responseGO:0031347140.020
heart developmentGO:00075073130.020
lymphocyte activationGO:0046649100.020
developmental maturationGO:0021700340.020
regulation of programmed cell deathGO:00430671010.020
regulation of i kappab kinase nf kappab signalingGO:004312240.019
positive regulation of cytokine productionGO:000181920.019
actin filament based processGO:0030029640.019
regulation of growthGO:0040008420.019
regulation of protein targetingGO:190353320.019
positive regulation of histone modificationGO:003105810.019
stem cell fate commitmentGO:004886510.019
ion transportGO:00068111140.019
motor neuron axon guidanceGO:0008045230.019
cytoplasmic pattern recognition receptor signaling pathwayGO:000275310.018
regulation of epithelial cell proliferationGO:005067830.018
synaptic growth at neuromuscular junctionGO:005112420.018
regulation of protein kinase activityGO:0045859150.018
mitochondrion organizationGO:000700540.018
humoral immune response mediated by circulating immunoglobulinGO:000245530.018
gtp catabolic processGO:000618420.018
regulation of sequestering of calcium ionGO:005128240.018
immunoglobulin productionGO:000237710.018
positive regulation of transcription dna templatedGO:0045893570.018
long chain fatty acid metabolic processGO:000167610.018
regulation of synapse organizationGO:005080730.018
fatty acid elongationGO:003049710.018
positive regulation of cellular component biogenesisGO:004408930.017
very long chain fatty acid metabolic processGO:000003840.017
actomyosin structure organizationGO:0031032530.017
deathGO:00162651210.017
osteoclast differentiationGO:003031610.017
regulation of production of molecular mediator of immune responseGO:000270010.017
vacuolar transportGO:000703420.017
determination of left right symmetryGO:00073681790.017
regulation of endopeptidase activityGO:0052548230.017
cell motilityGO:00488702440.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
regulation of rho protein signal transductionGO:003502320.016
response to molecule of bacterial originGO:0002237140.016
muscle attachmentGO:001620390.016
regulation of actin cytoskeleton organizationGO:003295680.016
regulation of protein phosphorylationGO:0001932180.016
phosphatidylinositol 3 kinase signalingGO:001406520.016
calcium ion homeostasisGO:0055074190.016
actin cytoskeleton organizationGO:0030036630.016
regulation of apoptotic processGO:0042981980.016
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.016
positive regulation of chromatin modificationGO:190331010.016
adherens junction maintenanceGO:003433420.016
regulation of synapse assemblyGO:005196330.016
positive regulation of inflammatory responseGO:005072910.016
regulation of calcium ion transportGO:005192420.016
cell proliferation in forebrainGO:002184630.016
homeostasis of number of cellsGO:0048872620.016
neurological system processGO:0050877620.016
negative regulation of developmental processGO:0051093650.016
cell morphogenesis involved in differentiationGO:00009041950.016
positive regulation of peptidase activityGO:0010952100.016
regulation of response to stressGO:0080134360.015
positive regulation of lipid metabolic processGO:004583410.015
cation transportGO:0006812810.015
peptide transportGO:001583310.015
regulation of intracellular signal transductionGO:1902531570.015
organelle fusionGO:004828430.015
ion homeostasisGO:0050801410.015
epithelial cell morphogenesisGO:000338220.015
protein localizationGO:0008104400.015
positive regulation of signalingGO:0023056560.015
positive regulation of molecular functionGO:0044093330.015
regulation of myotube differentiationGO:001083020.015
response to external stimulusGO:00096052640.014
regulation of cellular carbohydrate metabolic processGO:001067540.014
regulation of cell projection assemblyGO:006049140.014
cellular response to molecule of bacterial originGO:007121930.014
cellular response to chemical stimulusGO:00708871570.014
actin filament bundle assemblyGO:005101760.014
lipid storageGO:001991510.014
cellular amide metabolic processGO:004360340.014
regulation of establishment or maintenance of cell polarityGO:003287820.014
melanin metabolic processGO:000658220.014
multicellular organism reproductionGO:0032504350.014
macroautophagyGO:001623610.014
positive regulation of catalytic activityGO:0043085250.014
macromolecule localizationGO:0033036540.014
sexual reproductionGO:0019953360.014
leukocyte migrationGO:0050900150.014
alcohol biosynthetic processGO:004616520.014
nucleotide metabolic processGO:0009117280.014
positive regulation of dna metabolic processGO:005105410.014
organelle organizationGO:00069962270.013
tyrosine phosphorylation of stat3 proteinGO:004250310.013
regulation of reproductive processGO:200024140.013
cellular response to biotic stimulusGO:007121630.013
g1 s transition of mitotic cell cycleGO:000008210.013
positive regulation of map kinase activityGO:004340630.013
glial cell proliferationGO:001400940.013
regulation of cell migrationGO:0030334400.013
positive regulation of leukocyte mediated immunityGO:000270510.013
reactive oxygen species biosynthetic processGO:190340910.013
very long chain fatty acid biosynthetic processGO:004276140.013
neuron projection morphogenesisGO:00488121610.013
organic acid metabolic processGO:0006082310.013
long chain fatty acid transportGO:001590910.013
response to hypoxiaGO:0001666250.013
positive regulation of immune effector processGO:000269930.013
positive regulation of epithelial cell proliferationGO:005067910.013
fatty acid biosynthetic processGO:000663340.013
inositol lipid mediated signalingGO:004801720.013
single organism organelle organizationGO:19025891990.013
muscle tissue developmentGO:00605371100.013
positive regulation of multi organism processGO:004390230.013
regulation of kinase activityGO:0043549150.013
positive regulation of camp biosynthetic processGO:003081920.012
oocyte maturationGO:000155640.012
nitric oxide biosynthetic processGO:000680920.012
cellular response to hypoxiaGO:007145610.012
type i interferon productionGO:003260620.012
regulation of homeostatic processGO:003284490.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
regulation of response to biotic stimulusGO:000283120.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
positive regulation of rna metabolic processGO:0051254590.012
regulation of phosphate metabolic processGO:0019220430.012
positive regulation of jnk cascadeGO:004633030.012
protein acetylationGO:000647320.012
neuroblast proliferationGO:000740520.012
regulation of dendrite developmentGO:005077330.012
anion transportGO:0006820380.012
regulation of dna replicationGO:000627530.012
metal ion transportGO:0030001580.012
protein importGO:001703830.012
regulation of interferon beta productionGO:003264810.012
female gonad developmentGO:000858540.012
modulation by virus of host morphology or physiologyGO:001904810.012
anatomical structure homeostasisGO:0060249360.012
antimicrobial humoral responseGO:001973020.012
positive regulation of phosphate metabolic processGO:0045937210.012
blood circulationGO:0008015870.012
neuroblast fate determinationGO:000740010.012
erk1 and erk2 cascadeGO:007037140.012
metal ion homeostasisGO:0055065260.012
cell cell junction organizationGO:0045216100.011
regulation of camp metabolic processGO:003081490.011
collagen metabolic processGO:003296320.011
spermatid differentiationGO:004851520.011
action potentialGO:0001508190.011
response to monosaccharideGO:003428430.011
negative regulation of cellular processGO:00485232830.011
guanosine containing compound catabolic processGO:190106920.011
cellular amino acid metabolic processGO:000652070.011
positive regulation of endopeptidase activityGO:0010950100.011
protein phosphorylationGO:0006468470.011
dna templated transcription elongationGO:000635430.011
regulation of protein complex assemblyGO:004325430.011
peptidyl serine modificationGO:001820920.011
programmed cell deathGO:00125011190.011
positive regulation of protein metabolic processGO:0051247230.011
eye developmentGO:00016542770.011
regulation of cytoplasmic transportGO:190364940.011
negative regulation of response to stimulusGO:00485851040.011
cell part morphogenesisGO:00329902460.011
negative regulation of cellular component movementGO:0051271180.011
membrane repolarizationGO:008600920.011
regulation of nervous system developmentGO:0051960900.011
regulation of cytokine mediated signaling pathwayGO:000195930.011
regulation of transferase activityGO:0051338160.011
regulation of peptidase activityGO:0052547230.011
tissue remodelingGO:004877140.011
growth plate cartilage morphogenesisGO:000342210.011
regulation of ras gtpase activityGO:003231820.011
multicellular organismal homeostasisGO:0048871290.011
response to glucocorticoidGO:005138410.011
cellular response to oxygen levelsGO:007145310.011
dna catabolic processGO:000630810.011
autophagyGO:000691440.011
regulation of cell substrate adhesionGO:001081010.011
positive regulation of leukocyte differentiationGO:190210710.011
positive regulation of translationGO:004572710.011
negative regulation of neural precursor cell proliferationGO:200017810.011
transcription from rna polymerase ii promoterGO:0006366800.010
negative regulation of signalingGO:0023057960.010
stem cell fate determinationGO:004886710.010
calcium mediated signalingGO:001972220.010
regionalizationGO:00030022740.010
positive regulation of multicellular organismal processGO:0051240520.010
regulation of bone mineralizationGO:003050020.010
regulation of cell proliferationGO:0042127370.010
toll like receptor signaling pathwayGO:000222440.010
regulation of mitochondrion organizationGO:001082110.010
g protein coupled receptor signaling pathwayGO:0007186740.010
regulation of carbohydrate metabolic processGO:000610940.010
cellular localizationGO:0051641970.010
positive regulation of immune responseGO:0050778110.010
circulatory system processGO:0003013870.010
response to growth factorGO:0070848390.010
regulation of cellular component movementGO:0051270550.010
response to drugGO:004249330.010
nucleoside triphosphate biosynthetic processGO:000914220.010
positive regulation of cell cycleGO:004578730.010
chordate embryonic developmentGO:00430092710.010
production of molecular mediator of immune responseGO:000244020.010
nucleobase containing small molecule metabolic processGO:0055086320.010
mesenchymal cell differentiationGO:0048762870.010
somatic cell dna recombinationGO:001644410.010
response to amphetamineGO:000197510.010
positive regulation of endothelial cell proliferationGO:000193810.010

ighm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.014
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
nervous system diseaseDOID:86300.011