Danio rerio

23 known processes

dclk2

doublecortin-like kinase 2

(Aliases: sb:cb572,dclk,cb572,MGC174949,si:dkey-180n16.1)

dclk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of biological processGO:00485193040.446
Worm
negative regulation of purine nucleotide metabolic processGO:190054370.275
response to chemicalGO:00422213200.255
agingGO:000756820.224
ribonucleotide metabolic processGO:0009259270.188
regulation of cyclic nucleotide metabolic processGO:0030799150.183
cognitionGO:005089010.182
brain developmentGO:00074202930.179
regulation of adenylate cyclase activityGO:004576160.177
heterocycle metabolic processGO:00464832900.175
regulation of purine nucleotide metabolic processGO:1900542170.169
response to external stimulusGO:00096052640.154
regulation of nucleotide catabolic processGO:003081120.154
regulation of multicellular organismal processGO:00512392770.149
purine containing compound metabolic processGO:0072521290.143
regulation of purine nucleotide catabolic processGO:003312120.142
multicellular organism growthGO:003526440.135
guanosine containing compound metabolic processGO:190106840.130
cellular component movementGO:00069283350.126
regulation of cyclase activityGO:0031279120.123
generation of neuronsGO:00486993850.122
carbohydrate derivative metabolic processGO:1901135610.115
regulation of biological qualityGO:00650082630.114
nucleobase containing compound metabolic processGO:00061392740.114
blood vessel morphogenesisGO:00485142160.113
regulation of signalingGO:00230512350.112
regulation of cellular metabolic processGO:00313233200.111
ribose phosphate metabolic processGO:0019693270.108
biosynthetic processGO:00090582940.107
central nervous system developmentGO:00074173870.106
regulation of primary metabolic processGO:00800903110.105
positive regulation of biological processGO:00485182530.104
cell morphogenesis involved in differentiationGO:00009041950.101
cyclic nucleotide biosynthetic processGO:0009190180.101
cellular response to chemical stimulusGO:00708871570.100
purine nucleotide metabolic processGO:0006163270.100
organonitrogen compound metabolic processGO:1901564740.098
cellular nitrogen compound metabolic processGO:00346412900.094
regulation of nucleotide metabolic processGO:0006140170.093
signal transductionGO:00071654550.091
gtp metabolic processGO:004603940.090
regulation of multicellular organism growthGO:004001440.090
regulation of nucleobase containing compound metabolic processGO:00192192500.088
maintenance of locationGO:005123540.087
regulation of filopodium assemblyGO:005148920.086
single organism organelle organizationGO:19025891990.086
Worm
purine ribonucleotide metabolic processGO:0009150270.084
cellular aromatic compound metabolic processGO:00067252950.084
gtp catabolic processGO:000618420.082
organophosphate metabolic processGO:0019637370.082
negative regulation of cellular processGO:00485232830.081
Worm
nucleobase containing compound biosynthetic processGO:00346542050.081
regulation of metabolic processGO:00192223590.080
nucleoside phosphate metabolic processGO:0006753280.080
regulation of cell communicationGO:00106462320.078
neuron differentiationGO:00301823530.077
positive regulation of cellular catabolic processGO:003133130.076
negative regulation of cellular metabolic processGO:0031324770.076
small molecule metabolic processGO:0044281770.075
negative regulation of nucleobase containing compound metabolic processGO:0045934590.075
regulation of gtp catabolic processGO:003312420.074
vasculature developmentGO:00019442780.073
guanosine containing compound catabolic processGO:190106920.072
g protein coupled receptor signaling pathwayGO:0007186740.070
nitrogen compound metabolic processGO:00068073190.070
positive regulation of catabolic processGO:000989640.067
positive regulation of cell cycleGO:004578730.064
growthGO:00400071740.064
epithelial tube morphogenesisGO:00605621480.063
regulation of sequestering of calcium ionGO:005128240.063
negative regulation of catabolic processGO:000989530.062
regulation of signal transductionGO:00099662250.061
angiogenesisGO:00015251580.059
regulation of developmental processGO:00507932470.059
neuron projection morphogenesisGO:00488121610.058
neuron projection developmentGO:00311751800.058
positive regulation of purine nucleotide catabolic processGO:003312310.057
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.057
head developmentGO:00603223030.057
morphogenesis of an epitheliumGO:00020093330.056
cellular response to organic substanceGO:00713101050.056
nucleobase containing small molecule metabolic processGO:0055086320.055
cell surface receptor signaling pathwayGO:00071663250.055
positive regulation of developmental processGO:0051094500.054
cell migrationGO:00164772370.054
cyclic purine nucleotide metabolic processGO:0052652180.054
regulation of response to stimulusGO:00485832690.054
larval developmentGO:000216420.054
regulation of metal ion transportGO:001095940.054
axonogenesisGO:00074091520.054
response to organic substanceGO:00100331530.052
cell morphogenesisGO:00009022890.051
regulation of lyase activityGO:0051339120.050
organic substance biosynthetic processGO:19015762890.048
cellular component morphogenesisGO:00329893360.048
regulation of cell developmentGO:00602841000.047
response to nutrientGO:000758430.047
cellular biosynthetic processGO:00442492860.046
negative regulation of sequestering of calcium ionGO:005128340.046
regulation of molecular functionGO:0065009700.045
cellular macromolecule metabolic processGO:00442603910.045
adult behaviorGO:003053420.045
cell projection organizationGO:00300302840.045
protein metabolic processGO:00195381830.045
cell morphogenesis involved in neuron differentiationGO:00486671630.044
cell motilityGO:00488702440.044
regulation of gtpase activityGO:004308720.044
sequestering of metal ionGO:005123830.044
positive regulation of gtp catabolic processGO:003312610.044
response to drugGO:004249330.044
response to antibioticGO:004667710.043
embryonic heart tube developmentGO:00350501330.043
regulation of inflammatory responseGO:005072720.043
regulation of nitrogen compound metabolic processGO:00511712510.043
cellular nitrogen compound biosynthetic processGO:00442712180.043
establishment of localizationGO:00512342440.043
Worm
regulation of cell projection assemblyGO:006049140.043
phosphorus metabolic processGO:00067931090.043
protein localization to nucleusGO:003450430.043
organic cyclic compound biosynthetic processGO:19013622230.042
chordate embryonic developmentGO:00430092710.042
regulation of membrane potentialGO:0042391230.042
apoptotic processGO:00069151160.042
regulation of biosynthetic processGO:00098892500.042
regulation of cyclic nucleotide biosynthetic processGO:0030802150.041
organic cyclic compound metabolic processGO:19013603010.041
regulation of localizationGO:00328791040.041
organophosphate biosynthetic processGO:0090407230.040
regulation of nucleotide biosynthetic processGO:0030808150.039
negative regulation of cellular catabolic processGO:003133030.039
cellular response to oxygen levelsGO:007145310.038
negative regulation of metabolic processGO:0009892860.038
phosphate containing compound metabolic processGO:00067961080.038
aromatic compound biosynthetic processGO:00194382170.038
skin developmentGO:0043588540.038
purine ribonucleoside monophosphate catabolic processGO:000916940.038
intracellular signal transductionGO:0035556850.037
lipid storageGO:001991510.037
embryonic heart tube morphogenesisGO:00031431080.037
regulation of cellular amine metabolic processGO:003323800.037
cellular response to decreased oxygen levelsGO:003629410.037
sequestering of calcium ionGO:005120830.037
positive regulation of transportGO:005105020.036
positive regulation of cellular metabolic processGO:0031325940.036
positive regulation of nitrogen compound metabolic processGO:0051173690.036
regulation of rna biosynthetic processGO:20011412130.035
positive regulation of gtpase activityGO:004354710.035
embryo development ending in birth or egg hatchingGO:00097922710.035
cellular macromolecule biosynthetic processGO:00346452240.035
blood vessel developmentGO:00015682460.035
regulation of autophagyGO:001050630.034
cell part morphogenesisGO:00329902460.034
tube morphogenesisGO:00352393490.034
ribonucleotide biosynthetic processGO:0009260200.034
negative regulation of cell communicationGO:0010648960.034
nucleic acid metabolic processGO:00903042440.034
cyclic nucleotide metabolic processGO:0009187180.034
negative regulation of catalytic activityGO:0043086210.033
single organism metabolic processGO:00447102170.033
ear developmentGO:00435831270.032
rho protein signal transductionGO:000726650.032
regulation of neurogenesisGO:0050767870.032
transmembrane transportGO:00550851200.032
response to endogenous stimulusGO:0009719830.032
macromolecule modificationGO:00434121110.032
developmental growthGO:00485891660.032
establishment of localization in cellGO:0051649770.031
Worm
mitochondrion organizationGO:000700540.031
nucleic acid templated transcriptionGO:00976591810.031
axon developmentGO:00615641660.030
multicellular organismal signalingGO:0035637220.030
negative regulation of nitrogen compound metabolic processGO:0051172590.030
single organism transportGO:00447652060.029
sensory organ developmentGO:00074233930.029
embryonic organ developmentGO:00485683810.029
positive regulation of cell communicationGO:0010647560.029
protein dephosphorylationGO:000647030.029
positive regulation of cellular component biogenesisGO:004408930.028
transportGO:00068102200.028
regulation of phosphorus metabolic processGO:0051174430.028
establishment of protein localization to organelleGO:007259440.028
positive regulation of metabolic processGO:00098931080.027
autophagyGO:000691440.026
heart morphogenesisGO:00030071560.026
regulation of tube sizeGO:003515020.026
negative regulation of nucleotide metabolic processGO:004598070.026
eye developmentGO:00016542770.026
cellular response to endogenous stimulusGO:0071495680.026
regulation of protein transportGO:005122330.026
cellular component biogenesisGO:00440851780.026
Worm
transcription dna templatedGO:00063511810.025
organic acid metabolic processGO:0006082310.025
cell projection morphogenesisGO:00488582440.025
response to woundingGO:00096111160.025
positive regulation of camp biosynthetic processGO:003081920.025
rna biosynthetic processGO:00327741810.025
cation transportGO:0006812810.025
positive regulation of nucleotide catabolic processGO:003081310.024
response to abiotic stimulusGO:00096281220.024
regulation of cellular macromolecule biosynthetic processGO:20001122220.024
negative regulation of mitosisGO:004583930.024
regulation of cellular amino acid metabolic processGO:000652100.024
regulation of intracellular signal transductionGO:1902531570.024
carboxylic acid metabolic processGO:0019752220.024
response to stressGO:00069502630.024
nucleoside phosphate biosynthetic processGO:1901293210.024
single organism localizationGO:19025782250.024
Worm
negative regulation of nuclear divisionGO:005178430.024
regulation of purine nucleotide biosynthetic processGO:1900371150.024
regulation of cell projection organizationGO:0031344440.023
protein heterooligomerizationGO:005129110.023
protein importGO:001703830.023
regulation of nucleoside metabolic processGO:000911820.023
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.023
regulation of nervous system developmentGO:0051960900.023
heterocycle biosynthetic processGO:00181302150.023
negative regulation of signalingGO:0023057960.023
locomotionGO:00400113130.023
Worm
regulation of macromolecule metabolic processGO:00602553170.023
regulation of neuron differentiationGO:0045664560.023
negative regulation of macromolecule metabolic processGO:0010605760.023
positive regulation of nucleoside metabolic processGO:004597910.022
cytosolic calcium ion transportGO:006040130.022
nucleotide metabolic processGO:0009117280.022
purine containing compound biosynthetic processGO:0072522200.022
regulation of locomotionGO:0040012550.022
synaptic transmission cholinergicGO:000727140.022
regulation of transcription dna templatedGO:00063552130.022
regulation of transmembrane transporter activityGO:002289820.022
positive regulation of cellular amine metabolic processGO:003324000.022
cellular response to hypoxiaGO:007145610.022
positive regulation of cytosolic calcium ion concentrationGO:000720440.022
response to decreased oxygen levelsGO:0036293250.022
phosphatidylinositol mediated signalingGO:004801520.022
purine nucleoside monophosphate catabolic processGO:000912840.022
carbohydrate derivative biosynthetic processGO:1901137430.022
female sex differentiationGO:004666040.021
development of primary female sexual characteristicsGO:004654540.021
regulation of camp metabolic processGO:003081490.021
negative regulation of cellular biosynthetic processGO:0031327550.021
ribonucleoside monophosphate catabolic processGO:000915840.021
negative regulation of response to stimulusGO:00485851040.021
single organism nuclear importGO:190259330.021
ras protein signal transductionGO:000726570.021
protein targeting to nucleusGO:004474430.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.021
positive regulation of cellular processGO:00485222010.021
regulation of intracellular protein transportGO:003315730.021
negative regulation of nucleotide biosynthetic processGO:003080970.020
response to amino acidGO:004320020.020
symbiosis encompassing mutualism through parasitismGO:004440340.020
lipid catabolic processGO:001604240.020
cation homeostasisGO:0055080330.020
regulation of anatomical structure morphogenesisGO:00226031300.020
neuroblast proliferationGO:000740520.019
inositol lipid mediated signalingGO:004801720.019
amine metabolic processGO:000930820.019
developmental maturationGO:0021700340.019
multicellular organismal metabolic processGO:004423620.019
regulation of rho protein signal transductionGO:003502320.019
nucleoside monophosphate catabolic processGO:000912540.019
cellular ion homeostasisGO:0006873170.019
positive regulation of secretionGO:005104710.019
heart developmentGO:00075073130.019
rna metabolic processGO:00160702190.018
positive regulation of purine nucleotide metabolic processGO:190054490.018
ion transportGO:00068111140.018
regulation of calcium ion transportGO:005192420.018
erythrocyte differentiationGO:0030218540.018
negative regulation of molecular functionGO:0044092230.018
nuclear transportGO:005116940.018
regulation of dendrite developmentGO:005077330.018
negative regulation of camp biosynthetic processGO:003081870.018
macromolecule biosynthetic processGO:00090592270.018
negative regulation of kinase activityGO:003367340.018
negative regulation of camp metabolic processGO:003081570.017
positive regulation of reproductive processGO:200024320.017
purine ribonucleotide biosynthetic processGO:0009152200.017
regulation of transporter activityGO:003240920.017
regulation of cell differentiationGO:00455951420.017
programmed cell deathGO:00125011190.017
developmental programmed cell deathGO:001062340.017
regulation of catalytic activityGO:0050790550.017
circulatory system processGO:0003013870.017
ion transmembrane transportGO:0034220910.017
stem cell fate commitmentGO:004886510.017
cellular response to drugGO:003569010.017
neurotransmitter transportGO:000683620.017
muscle cell developmentGO:00550011150.016
regulation of synaptic plasticityGO:004816710.016
positive regulation of response to stimulusGO:0048584800.016
calcium ion transport into cytosolGO:006040230.016
cell deathGO:00082191210.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
regulation of phosphate metabolic processGO:0019220430.016
fin regenerationGO:0031101510.016
negative regulation of signal transductionGO:0009968940.016
regulation of cellular protein metabolic processGO:0032268520.016
exocytosisGO:000688710.016
regulation of cellular ketone metabolic processGO:001056570.016
regulation of protein localization to nucleusGO:190018020.016
cellular amino acid metabolic processGO:000652070.016
negative regulation of mapk cascadeGO:004340940.016
retina development in camera type eyeGO:00600411460.016
female gonad developmentGO:000858540.015
erk1 and erk2 cascadeGO:007037140.015
regulation of establishment of protein localizationGO:007020140.015
cellular localizationGO:0051641970.015
Worm
positive regulation of nucleobase containing compound metabolic processGO:0045935690.015
action potentialGO:0001508190.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
immune system developmentGO:00025201910.015
ion homeostasisGO:0050801410.015
purine ribonucleoside triphosphate metabolic processGO:000920590.015
cellular amine metabolic processGO:004410620.015
regulation of multicellular organismal developmentGO:20000262230.015
ribonucleoside metabolic processGO:0009119110.015
muscle cell differentiationGO:00426921390.015
glycerophospholipid biosynthetic processGO:004647410.015
regulation of cytoplasmic transportGO:190364940.015
wound healingGO:0042060900.015
lipid homeostasisGO:005508830.014
protein import into nucleusGO:000660630.014
system processGO:00030081850.014
dna templated transcription initiationGO:000635210.014
oxoacid metabolic processGO:0043436310.014
g1 s transition of mitotic cell cycleGO:000008210.014
positive regulation of multicellular organismal processGO:0051240520.014
secondary metabolic processGO:001974830.014
multi organism cellular processGO:004476420.014
regulation of reproductive processGO:200024140.014
calcium ion transmembrane transportGO:0070588130.014
protein polyubiquitinationGO:000020940.014
macromolecule localizationGO:0033036540.013
positive regulation of secretion by cellGO:190353210.013
catechol containing compound metabolic processGO:000971220.013
positive regulation of camp metabolic processGO:003081620.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
immune system processGO:00023762410.013
gland developmentGO:00487321430.013
neuronal action potentialGO:0019228180.013
localization of cellGO:00516742440.013
glycosyl compound metabolic processGO:1901657110.013
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.013
cellular cation homeostasisGO:0030003170.013
regulation of blood vessel sizeGO:005088020.013
negative regulation of biosynthetic processGO:0009890550.013
negative regulation of gene expressionGO:0010629650.013
response to uvGO:000941130.013
developmental cell growthGO:0048588520.013
protein phosphorylationGO:0006468470.013
microtubule organizing center organizationGO:003102310.013
negative regulation of intracellular signal transductionGO:1902532220.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
cation transmembrane transportGO:0098655650.012
inorganic ion transmembrane transportGO:0098660570.012
regulation of mitochondrion organizationGO:001082110.012
regulation of macromolecule biosynthetic processGO:00105562250.012
cellular response to nutrient levelsGO:003166920.012
cellular component assemblyGO:00226071700.012
Worm
regulation of glucose transportGO:001082710.012
cellular catabolic processGO:0044248270.012
positive regulation of cyclic nucleotide metabolic processGO:003080180.012
response to vitaminGO:003327330.012
response to corticosteroidGO:003196010.012
negative regulation of cyclase activityGO:003128060.012
regulation of cell migrationGO:0030334400.012
intracellular transportGO:0046907320.012
cell cell signalingGO:0007267520.012
protein homooligomerizationGO:005126030.012
cellular macromolecule localizationGO:0070727210.012
neuron projection guidanceGO:0097485860.012
tor signalingGO:003192970.012
release of sequestered calcium ion into cytosolGO:005120930.012
membrane fusionGO:006102520.012
regulation of protein import into nucleusGO:004230620.012
regulation of neuron projection developmentGO:0010975400.012
immunoglobulin mediated immune responseGO:001606430.012
negative regulation of ras protein signal transductionGO:004658010.012
ph reductionGO:004585110.012
positive regulation of biosynthetic processGO:0009891680.012
response to nitrogen compoundGO:1901698190.011
organelle fusionGO:004828430.011
carboxylic acid catabolic processGO:004639530.011
homeostatic processGO:00425921420.011
regulation of cell deathGO:00109411030.011
response to organic cyclic compoundGO:0014070510.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
negative regulation of lyase activityGO:005135060.011
electron transport chainGO:002290020.011
organic cyclic compound catabolic processGO:1901361150.011
forebrain cell migrationGO:002188510.011
positive regulation of signalingGO:0023056560.011
purine nucleotide biosynthetic processGO:0006164200.011
neuron developmentGO:00486662620.011
striated muscle cell differentiationGO:00511461290.011
regulation of ion transmembrane transporter activityGO:003241220.011
negative regulation of rna metabolic processGO:0051253480.011
cellular protein modification processGO:00064641000.011
negative regulation of dna metabolic processGO:005105340.011
positive regulation of cytoskeleton organizationGO:005149530.011
regulation of rna metabolic processGO:00512522240.011
small gtpase mediated signal transductionGO:000726480.011
nuclear importGO:005117030.011
cellular homeostasisGO:0019725260.011
cell substrate adhesionGO:003158940.011
actin filament based movementGO:003004810.011
response to acid chemicalGO:0001101170.011
regulation of camp biosynthetic processGO:003081790.011
cell proliferationGO:0008283800.011
multicellular organismal response to stressGO:003355520.011
regulation of cell motilityGO:2000145460.011
calcium mediated signalingGO:001972220.011
negative regulation of cyclic nucleotide biosynthetic processGO:003080370.011
organelle organizationGO:00069962270.011
Worm
negative regulation of protein kinase activityGO:000646940.010
tissue regenerationGO:0042246740.010
regulation of bindingGO:005109830.010
regulation of cell activationGO:005086510.010
regulation of gene expressionGO:00104682650.010
aromatic compound catabolic processGO:0019439150.010
filopodium assemblyGO:004684750.010
retina morphogenesis in camera type eyeGO:0060042790.010
negative regulation of apoptotic processGO:0043066550.010
cell growthGO:0016049570.010
divalent inorganic cation transportGO:0072511210.010
macromolecular complex disassemblyGO:003298410.010
Worm
transmission of nerve impulseGO:0019226190.010
single organism membrane fusionGO:004480120.010
camera type eye developmentGO:00430102220.010
nucleocytoplasmic transportGO:000691340.010
detection of external stimulusGO:0009581240.010
regulation of receptor mediated endocytosisGO:004825940.010
organic substance catabolic processGO:1901575280.010

dclk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.058
nervous system diseaseDOID:86300.058
disease of metabolismDOID:001466700.014
cardiovascular system diseaseDOID:128700.013