Danio rerio

28 known processes

pfn1

profilin 1

(Aliases: sb:cb813,wu:fa91a03)

pfn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of filopodium assemblyGO:005148920.611
actin polymerization or depolymerizationGO:000815420.390
positive regulation of cytoskeleton organizationGO:005149530.348
cytoplasm organizationGO:000702840.253
regulation of biological qualityGO:00650082630.167
regulation of cell projection assemblyGO:006049140.162
positive regulation of protein polymerizationGO:003227320.158
guanosine containing compound catabolic processGO:190106920.139
single organism organelle organizationGO:19025891990.130
cytokinesisGO:000091030.130
phagocytosisGO:000690930.129
regulation of peptidyl tyrosine phosphorylationGO:005073010.127
larval developmentGO:000216420.122
actin filament based processGO:0030029640.119
positive regulation of cellular component biogenesisGO:004408930.119
organic substance transportGO:0071702580.108
protein localization to plasma membraneGO:007265910.106
organelle organizationGO:00069962270.102
regulation of protein polymerizationGO:003227120.098
cytoskeleton organizationGO:0007010960.094
muscle cell differentiationGO:00426921390.091
single organism transportGO:00447652060.090
organonitrogen compound biosynthetic processGO:1901566470.089
organelle fusionGO:004828430.087
extrinsic apoptotic signaling pathwayGO:009719130.086
cognitionGO:005089010.085
cellular localizationGO:0051641970.082
response to stressGO:00069502630.081
adherens junction organizationGO:003433240.077
cellular biosynthetic processGO:00442492860.074
regulation of actin cytoskeleton organizationGO:003295680.073
membrane lipid biosynthetic processGO:004646720.073
positive regulation of transportGO:005105020.072
cellular component biogenesisGO:00440851780.072
organic substance biosynthetic processGO:19015762890.072
cell substrate junction assemblyGO:000704420.072
muscle structure developmentGO:00610611960.071
establishment of protein localization to organelleGO:007259440.070
ion transportGO:00068111140.069
regulation of cell activationGO:005086510.069
single organism biosynthetic processGO:0044711710.068
fatty acid biosynthetic processGO:000663340.067
embryo development ending in birth or egg hatchingGO:00097922710.066
single organism localizationGO:19025782250.066
transportGO:00068102200.064
negative regulation of protein serine threonine kinase activityGO:007190120.062
phagocytosis engulfmentGO:000691110.062
cell projection assemblyGO:0030031640.059
response to external stimulusGO:00096052640.057
negative regulation of kinase activityGO:003367340.056
positive regulation of gtpase activityGO:004354710.056
regulation of water loss via skinGO:003356110.056
sphingolipid biosynthetic processGO:003014820.055
peptidyl threonine phosphorylationGO:001810710.055
cellular response to chemical stimulusGO:00708871570.055
nuclear transportGO:005116940.054
regulation of protein import into nucleusGO:004230620.054
epithelial cell differentiationGO:00308551160.054
regulation of cellular component organizationGO:0051128860.054
leukocyte proliferationGO:007066110.053
gtp metabolic processGO:004603940.053
protein import into nucleusGO:000660630.052
cellular component morphogenesisGO:00329893360.052
regulation of inflammatory responseGO:005072720.051
regulation of nucleotide catabolic processGO:003081120.051
mononuclear cell proliferationGO:003294310.051
positive regulation of protein complex assemblyGO:003133420.050
actin filament polymerizationGO:003004120.048
cellular ketone metabolic processGO:0042180110.047
pole plasm assemblyGO:000731540.047
negative regulation of biological processGO:00485193040.046
organic cyclic compound metabolic processGO:19013603010.046
positive regulation of notch signaling pathwayGO:004574730.045
maintenance of locationGO:005123540.045
nuclear importGO:005117030.045
positive regulation of biological processGO:00485182530.045
agingGO:000756820.044
cellular component assemblyGO:00226071700.044
cell deathGO:00082191210.044
syncytium formationGO:0006949120.044
hemopoiesisGO:00300971830.044
establishment of localizationGO:00512342440.043
response to glucoseGO:000974930.042
small molecule metabolic processGO:0044281770.042
negative regulation of protein kinase activityGO:000646940.041
cell surface receptor signaling pathwayGO:00071663250.041
defense responseGO:0006952470.041
regulation of nucleobase containing compound metabolic processGO:00192192500.041
nucleic acid metabolic processGO:00903042440.040
cell morphogenesisGO:00009022890.040
regulation of multicellular organism growthGO:004001440.040
signal transductionGO:00071654550.040
homeostatic processGO:00425921420.039
neurotransmitter secretionGO:000726920.038
protein heterooligomerizationGO:005129110.037
cellular component assembly involved in morphogenesisGO:00109271070.037
protein targeting to nucleusGO:004474430.037
morphogenesis of an epitheliumGO:00020093330.036
actin cytoskeleton organizationGO:0030036630.035
homeostasis of number of cellsGO:0048872620.034
wound healingGO:0042060900.034
gtp catabolic processGO:000618420.034
positive regulation of defense response to virus by hostGO:000223000.033
regulation of protein transportGO:005122330.033
rna localizationGO:000640340.033
immune system processGO:00023762410.033
nucleobase containing compound metabolic processGO:00061392740.033
multicellular organism growthGO:003526440.032
negative regulation of protein phosphorylationGO:000193340.032
medulla oblongata developmentGO:002155040.031
regulation of wound healingGO:006104120.031
regulation of establishment of protein localizationGO:007020140.031
regulation of protein complex disassemblyGO:004324410.031
maternal determination of anterior posterior axis embryoGO:000835840.031
protein importGO:001703830.031
cellular component maintenanceGO:004395430.031
nitrogen compound metabolic processGO:00068073190.030
positive regulation of cell communicationGO:0010647560.030
protein complex assemblyGO:0006461300.030
organonitrogen compound metabolic processGO:1901564740.030
regulation of nitrogen compound metabolic processGO:00511712510.030
negative regulation of defense responseGO:003134820.029
adherens junction assemblyGO:003433310.029
stem cell maintenanceGO:001982740.029
intracellular mrna localizationGO:000829810.029
single organism nuclear importGO:190259330.028
single organism membrane fusionGO:004480120.028
positive regulation of catabolic processGO:000989640.028
protein polymerizationGO:005125840.028
sarcomere organizationGO:0045214260.028
regulation of immune system processGO:0002682340.027
cell cycle processGO:0022402530.027
response to woundingGO:00096111160.027
erk1 and erk2 cascadeGO:007037140.027
cellular response to organic substanceGO:00713101050.027
positive regulation of embryonic developmentGO:004001930.027
regulation of protein targetingGO:190353320.027
regulation of protein localization to nucleusGO:190018020.027
negative regulation of mapk cascadeGO:004340940.026
positive regulation of erk1 and erk2 cascadeGO:007037420.026
protein metabolic processGO:00195381830.026
muscle cell developmentGO:00550011150.026
amine metabolic processGO:000930820.026
regulation of i kappab kinase nf kappab signalingGO:004312240.025
autophagyGO:000691440.025
blood vessel morphogenesisGO:00485142160.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
regulation of cytoskeleton organizationGO:0051493110.025
organism emergence from protective structureGO:007168440.024
response to biotic stimulusGO:0009607970.024
multicellular organismal water homeostasisGO:005089110.024
plasma membrane repairGO:000177820.024
lymphocyte proliferationGO:004665110.024
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.024
organic hydroxy compound transportGO:0015850140.024
regulation of gtpase activityGO:004308720.024
positive regulation of gtp catabolic processGO:003312610.024
regulation of organelle organizationGO:0033043290.024
notch signaling pathwayGO:0007219350.023
protein localization to nucleusGO:003450430.023
positive regulation of cellular catabolic processGO:003133130.023
regulation of response to stimulusGO:00485832690.023
t cell activationGO:004211060.023
negative regulation of response to stimulusGO:00485851040.023
carboxylic acid metabolic processGO:0019752220.022
polyol transportGO:001579170.022
positive regulation of cell matrix adhesionGO:000195410.022
nucleocytoplasmic transportGO:000691340.022
apoptotic signaling pathwayGO:0097190230.022
regulation of cell cycleGO:0051726520.021
regulation of signal transductionGO:00099662250.021
regulation of stem cell differentiationGO:200073640.021
regulation of gtp catabolic processGO:003312420.021
regulation of apoptotic processGO:0042981980.021
positive regulation of response to stimulusGO:0048584800.021
mitotic cell cycleGO:0000278640.021
regulation of nucleocytoplasmic transportGO:004682220.021
protein depolymerizationGO:005126110.021
transmembrane transportGO:00550851200.021
defense response to fungusGO:005083220.021
heterocycle metabolic processGO:00464832900.020
cellular macromolecule localizationGO:0070727210.020
regulation of purine nucleotide catabolic processGO:003312120.020
regulation of cellular amino acid metabolic processGO:000652100.020
ectodermal cell fate specificationGO:000171520.020
regulation of cell communicationGO:00106462320.020
regulation of signalingGO:00230512350.019
regulation of transcription dna templatedGO:00063552130.019
cellular protein localizationGO:0034613200.019
cellular macromolecule metabolic processGO:00442603910.019
multi organism processGO:00517041340.019
regulation of ectoderm developmentGO:200038320.019
eye developmentGO:00016542770.019
i kappab kinase nf kappab signalingGO:000724940.019
protein complex disassemblyGO:004324110.019
response to chemicalGO:00422213200.019
negative regulation of cellular processGO:00485232830.019
urea transmembrane transportGO:007191890.019
cellular amine metabolic processGO:004410620.019
cellular nitrogen compound metabolic processGO:00346412900.018
single organism metabolic processGO:00447102170.018
posttranscriptional regulation of gene expressionGO:0010608140.018
ion transmembrane transportGO:0034220910.018
axis specificationGO:0009798430.018
embryonic organ developmentGO:00485683810.018
oocyte anterior posterior axis specificationGO:000731440.018
macromolecule localizationGO:0033036540.018
digestive tract developmentGO:00485652650.018
locomotionGO:00400113130.018
long chain fatty acid metabolic processGO:000167610.017
establishment of protein localization to plasma membraneGO:009000210.017
axon developmentGO:00615641660.017
response to organic substanceGO:00100331530.017
membrane raft organizationGO:003157910.017
leukocyte homeostasisGO:000177620.017
regulation of nucleoside metabolic processGO:000911820.017
myeloid cell homeostasisGO:0002262560.017
intestinal absorptionGO:005089220.017
cell motilityGO:00488702440.017
metal ion transportGO:0030001580.017
regulation of rho gtpase activityGO:003231910.017
striated muscle cell developmentGO:00550021080.017
membrane fusionGO:006102520.017
membrane invaginationGO:001032410.017
regulation of interferon beta productionGO:003264810.017
protein complex biogenesisGO:0070271300.017
gene expressionGO:00104672520.017
lymphocyte activationGO:0046649100.017
deathGO:00162651210.017
single organism cellular localizationGO:1902580460.017
regulation of ion transmembrane transporter activityGO:003241220.017
cell activationGO:0001775160.016
guanosine containing compound metabolic processGO:190106840.016
peptide transportGO:001583310.016
neurotransmitter transportGO:000683620.016
positive regulation of cellular amine metabolic processGO:003324000.016
regulation of cellular component sizeGO:0032535300.016
regulation of mitotic cell cycleGO:0007346250.016
cellular response to lipopolysaccharideGO:007122230.016
regulation of intracellular protein transportGO:003315730.016
macromolecule biosynthetic processGO:00090592270.016
regulation of anatomical structure sizeGO:0090066330.016
regulation of cellular amine metabolic processGO:003323800.016
protein acetylationGO:000647320.016
protein complex subunit organizationGO:0071822460.016
response to amino acidGO:004320020.016
cell agingGO:000756920.016
regulation of cytoplasmic transportGO:190364940.016
cell substrate adherens junction assemblyGO:000704510.015
cellular macromolecule biosynthetic processGO:00346452240.015
positive regulation of signalingGO:0023056560.015
cellular response to biotic stimulusGO:007121630.015
multicellular organismal reproductive processGO:0048609350.015
regulation of cellular ketone metabolic processGO:001056570.015
regulation of response to cytokine stimulusGO:006075930.015
response to external biotic stimulusGO:0043207970.015
neuron differentiationGO:00301823530.015
very long chain fatty acid biosynthetic processGO:004276140.015
peptidyl lysine acetylationGO:001839420.015
negative regulation of nuclear divisionGO:005178430.015
negative regulation of metabolic processGO:0009892860.015
oxoacid metabolic processGO:0043436310.015
oocyte constructionGO:000730850.015
generation of neuronsGO:00486993850.015
regulation of transmembrane transporter activityGO:002289820.015
cellular protein complex assemblyGO:0043623190.015
cortical cytoskeleton organizationGO:003086510.014
regulation of erk1 and erk2 cascadeGO:007037240.014
hatchingGO:003518840.014
positive regulation of purine nucleotide metabolic processGO:190054490.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
b cell differentiationGO:003018310.014
regulation of cell shapeGO:000836010.014
meiotic nuclear divisionGO:000712640.014
glucose homeostasisGO:004259310.014
negative regulation of myeloid cell differentiationGO:004563810.014
cellular component disassemblyGO:002241110.014
system processGO:00030081850.014
cellular aromatic compound metabolic processGO:00067252950.014
regulation of bindingGO:005109830.014
regulation of protein depolymerizationGO:190187910.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
negative regulation of intracellular transportGO:003238730.014
cellular protein metabolic processGO:00442671290.014
posterior lateral line developmentGO:0048916380.014
positive regulation of nucleotide catabolic processGO:003081310.014
regulation of blood pressureGO:000821710.013
cellular component movementGO:00069283350.013
regulation of primary metabolic processGO:00800903110.013
regulation of anatomical structure morphogenesisGO:00226031300.013
syncytium formation by plasma membrane fusionGO:0000768120.013
localization of cellGO:00516742440.013
cell cycle g1 s phase transitionGO:004484310.013
convergent extension involved in gastrulationGO:0060027710.013
fatty acid elongation unsaturated fatty acidGO:001936810.013
hemostasisGO:0007599130.013
myelin assemblyGO:003228810.013
vesicle mediated transportGO:0016192220.013
regulation of catenin import into nucleusGO:003541220.013
chordate embryonic developmentGO:00430092710.013
macromolecular complex disassemblyGO:003298410.013
positive regulation of nucleoside metabolic processGO:004597910.013
regenerationGO:0031099910.013
transcription dna templatedGO:00063511810.013
organic acid metabolic processGO:0006082310.013
multi organism reproductive processGO:0044703360.013
biosynthetic processGO:00090582940.013
cellular carbohydrate metabolic processGO:004426240.012
brain developmentGO:00074202930.012
striated muscle cell differentiationGO:00511461290.012
protein secretionGO:000930610.012
post golgi vesicle mediated transportGO:000689210.012
cortical actin cytoskeleton organizationGO:003086610.012
cellular protein complex disassemblyGO:004362410.012
reactive oxygen species metabolic processGO:007259360.012
b cell activationGO:004211320.012
lamellipodium assemblyGO:003003210.012
regulation of ras gtpase activityGO:003231820.012
dorsal ventral pattern formationGO:00099531250.012
leukocyte activationGO:0045321120.012
negative regulation of molecular functionGO:0044092230.012
negative regulation of cytokine mediated signaling pathwayGO:000196020.011
epithelial cell developmentGO:0002064420.011
ameboidal type cell migrationGO:00016671430.011
nuclear migrationGO:000709730.011
nephron tubule morphogenesisGO:007207810.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
response to drugGO:004249330.011
cytokine mediated signaling pathwayGO:001922170.011
myotube differentiationGO:0014902450.011
stem cell proliferationGO:007208940.011
locomotor rhythmGO:004547530.011
ras protein signal transductionGO:000726570.011
cellular response to molecule of bacterial originGO:007121930.011
regulation of cell developmentGO:00602841000.011
regulation of defense response to virus by hostGO:005069110.011
g1 s transition of mitotic cell cycleGO:000008210.011
digestive tract morphogenesisGO:00485462310.011
cell migration involved in gastrulationGO:0042074790.011
regulation of cell differentiationGO:00455951420.011
regulation of macromolecule metabolic processGO:00602553170.011
cytokinetic processGO:003250620.011
aromatic compound biosynthetic processGO:00194382170.011
regulation of epithelial cell proliferationGO:005067830.011
mitochondrion organizationGO:000700540.011
fertilizationGO:000956630.011
vasculature developmentGO:00019442780.011
regulation of natural killer cell mediated immunityGO:000271510.010
interferon beta productionGO:003260810.010
nucleotide metabolic processGO:0009117280.010
positive regulation of cell activationGO:005086710.010
positive regulation of cell adhesionGO:004578510.010
regulation of cell morphogenesisGO:0022604420.010

pfn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.051
disease of metabolismDOID:001466700.021
immune system diseaseDOID:291400.018
integumentary system diseaseDOID:1600.016