Danio rerio

0 known processes

hmgb2b

high-mobility group box 2b

(Aliases: hmgb2,wu:fa20b02,im:6909096,hmgb2l,zgc:101854)

hmgb2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleobase containing compound metabolic processGO:00061392740.851
Human Mouse Rat
positive regulation of endothelial cell proliferationGO:000193810.847
Human
cellular aromatic compound metabolic processGO:00067252950.810
Human Mouse Rat
negative regulation of cellular processGO:00485232830.784
Human Mouse
nucleic acid metabolic processGO:00903042440.763
Human Mouse Rat
signal transductionGO:00071654550.756
Mouse
response to stressGO:00069502630.729
Human
organic substance biosynthetic processGO:19015762890.700
Human Mouse Rat
regulation of cellular metabolic processGO:00313233200.651
Human Mouse Rat
cellular nitrogen compound metabolic processGO:00346412900.649
Human Mouse Rat
larval developmentGO:000216420.613
cellular macromolecule metabolic processGO:00442603910.599
Human Mouse Rat
cellular macromolecule biosynthetic processGO:00346452240.582
Human Mouse Rat
macromolecule biosynthetic processGO:00090592270.556
Human Mouse Rat
gene expressionGO:00104672520.540
Human Mouse Rat
regulation of nucleobase containing compound metabolic processGO:00192192500.537
Human Mouse Rat
regulation of transcription dna templatedGO:00063552130.516
Human Mouse Rat
regulation of rna biosynthetic processGO:20011412130.458
Human Mouse Rat
spermatid developmentGO:000728620.457
Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.445
Human Mouse Rat
regulation of signal transductionGO:00099662250.439
Mouse
regulation of macromolecule biosynthetic processGO:00105562250.437
Human Mouse Rat
aromatic compound biosynthetic processGO:00194382170.412
Human Mouse Rat
mitotic cell cycleGO:0000278640.408
positive regulation of nuclease activityGO:003207510.405
Human
regulation of primary metabolic processGO:00800903110.400
Human Mouse Rat
single organism organelle organizationGO:19025891990.383
Mouse
regulation of biosynthetic processGO:00098892500.381
Human Mouse Rat
regulation of nucleic acid templated transcriptionGO:19035062130.377
Human Mouse Rat
microtubule based processGO:0007017600.355
cytoskeleton organizationGO:0007010960.350
heterocycle metabolic processGO:00464832900.342
Human Mouse Rat
programmed cell deathGO:00125011190.312
Mouse
regulation of rna metabolic processGO:00512522240.306
Human Mouse Rat
positive regulation of cellular processGO:00485222010.305
Human Mouse Rat
nucleic acid templated transcriptionGO:00976591810.293
Human Mouse Rat
regulation of macromolecule metabolic processGO:00602553170.291
Human Mouse Rat
regulation of signalingGO:00230512350.290
Mouse
organic cyclic compound metabolic processGO:19013603010.290
Human Mouse Rat
regulation of metabolic processGO:00192223590.277
Human Mouse Rat
nucleobase containing compound biosynthetic processGO:00346542050.257
Human Mouse Rat
negative regulation of nucleobase containing compound metabolic processGO:0045934590.252
Human
cell motilityGO:00488702440.248
Human
regulation of multicellular organismal developmentGO:20000262230.245
Human
deathGO:00162651210.234
Mouse
transcription dna templatedGO:00063511810.231
Human Mouse Rat
rna metabolic processGO:00160702190.230
Human Mouse Rat
cellular component movementGO:00069283350.229
Human
cellular process involved in reproduction in multicellular organismGO:0022412280.229
Mouse
spermatid differentiationGO:004851520.228
Mouse
localization of cellGO:00516742440.227
Human
myeloid cell differentiationGO:0030099860.215
Human
positive regulation of epithelial cell proliferationGO:005067910.209
Human
cellular response to lipopolysaccharideGO:007122230.206
Human
negative regulation of biological processGO:00485193040.205
Human Mouse
dna metabolic processGO:0006259270.204
Human Rat
response to external stimulusGO:00096052640.200
Human
single organism metabolic processGO:00447102170.191
Human
regulation of endothelial cell proliferationGO:000193610.191
Human
organic cyclic compound biosynthetic processGO:19013622230.190
Human Mouse Rat
nucleus organizationGO:000699770.185
Mouse
regulation of mitotic cell cycle embryonicGO:000979420.182
neuron differentiationGO:00301823530.181
negative regulation of signalingGO:0023057960.177
Mouse
positive regulation of cellular metabolic processGO:0031325940.176
Human Mouse Rat
cellular component assemblyGO:00226071700.171
cell deathGO:00082191210.168
Mouse
cell projection organizationGO:00300302840.164
hematopoietic or lymphoid organ developmentGO:00485341910.158
Human
negative regulation of ras protein signal transductionGO:004658010.155
muscle structure developmentGO:00610611960.152
macromolecular complex subunit organizationGO:0043933740.149
cellular response to dna damage stimulusGO:0006974240.146
Human
regulation of epithelial cell proliferationGO:005067830.146
Human
negative regulation of response to stimulusGO:00485851040.145
Mouse
heterocycle biosynthetic processGO:00181302150.143
Human Mouse Rat
nitrogen compound metabolic processGO:00068073190.143
Human Mouse Rat
cell surface receptor signaling pathwayGO:00071663250.140
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.138
Human Mouse Rat
apoptotic processGO:00069151160.136
Mouse
response to biotic stimulusGO:0009607970.130
Human
regulation of gene expressionGO:00104682650.127
Human Mouse Rat
biosynthetic processGO:00090582940.122
Human Mouse Rat
germ cell developmentGO:0007281220.121
Mouse
regulation of cell proliferationGO:0042127370.117
Human
organelle organizationGO:00069962270.117
Mouse
regulation of response to stimulusGO:00485832690.115
Mouse
regulation of nuclease activityGO:003206910.111
Human
cellular component morphogenesisGO:00329893360.110
generation of neuronsGO:00486993850.107
transcription from rna polymerase ii promoterGO:0006366800.105
Human Mouse
cell proliferationGO:0008283800.105
Human
cellular biosynthetic processGO:00442492860.100
Human Mouse Rat
regulation of cellular biosynthetic processGO:00313262450.099
Human Mouse Rat
locomotionGO:00400113130.099
Human
negative regulation of cell communicationGO:0010648960.098
Mouse
cellular component biogenesisGO:00440851780.095
response to organic substanceGO:00100331530.094
Human Mouse
regulation of embryonic developmentGO:0045995470.094
regulation of cell communicationGO:00106462320.088
Mouse
regulation of catalytic activityGO:0050790550.086
Human
regulation of myeloid cell differentiationGO:004563780.084
Human
single organism reproductive processGO:0044702400.083
Mouse
cellular response to stressGO:0033554620.083
Human
reproductionGO:0000003400.082
Mouse
negative regulation of rna biosynthetic processGO:1902679450.081
Human
erythrocyte differentiationGO:0030218540.081
Human
cellular response to chemical stimulusGO:00708871570.080
Human
response to other organismGO:0051707970.080
Human
embryonic organ developmentGO:00485683810.077
chromosome organizationGO:0051276310.074
stem cell proliferationGO:007208940.072
negative regulation of nucleic acid templated transcriptionGO:1903507450.072
Human
transportGO:00068102200.072
mrna processingGO:0006397140.071
regulation of protein complex assemblyGO:004325430.070
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.069
Mouse
regulation of cell deathGO:00109411030.066
Mouse
cellular response to biotic stimulusGO:007121630.065
Human
cellular component assembly involved in morphogenesisGO:00109271070.063
regulation of biological qualityGO:00650082630.062
Human
positive regulation of rna biosynthetic processGO:1902680570.062
Human Mouse Rat
double strand break repairGO:000630230.062
negative regulation of gene expressionGO:0010629650.061
Human
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.061
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.059
Human Mouse Rat
endothelial cell proliferationGO:0001935110.058
Human
sensory organ developmentGO:00074233930.057
maintenance of locationGO:005123540.056
regulation of multicellular organismal processGO:00512392770.056
Human
spermatogenesisGO:000728370.055
Mouse
negative regulation of signal transductionGO:0009968940.054
Mouse
positive regulation of carbohydrate metabolic processGO:004591310.054
response to chemicalGO:00422213200.053
Human Mouse
multi organism processGO:00517041340.053
Human Mouse
neuron developmentGO:00486662620.052
multicellular organismal reproductive processGO:0048609350.052
Mouse
positive regulation of cellular biosynthetic processGO:0031328680.051
Human Mouse Rat
positive regulation of cell proliferationGO:0008284150.051
Human
positive regulation of hydrolase activityGO:0051345130.050
Human
cell migrationGO:00164772370.049
Human
positive regulation of transcription dna templatedGO:0045893570.049
Human Mouse Rat
positive regulation of cellular carbohydrate metabolic processGO:001067610.048
embryo development ending in birth or egg hatchingGO:00097922710.047
digestive system developmentGO:00551232890.047
single organism localizationGO:19025782250.046
protein complex assemblyGO:0006461300.046
regulation of intracellular signal transductionGO:1902531570.045
cellular protein metabolic processGO:00442671290.045
rna stabilizationGO:004348940.045
rna biosynthetic processGO:00327741810.044
Human Mouse Rat
response to bacteriumGO:0009617580.043
Human
regulation of cell differentiationGO:00455951420.043
Human
rna transportGO:005065820.043
embryonic organ morphogenesisGO:00485622740.043
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.043
Human
negative regulation of rna metabolic processGO:0051253480.043
Human
positive regulation of response to stimulusGO:0048584800.043
negative regulation of rna splicingGO:003311910.043
chemotaxisGO:00069351040.042
Human
mitotic g2 dna damage checkpointGO:000709530.042
tube morphogenesisGO:00352393490.041
negative regulation of metabolic processGO:0009892860.041
Human
homeostatic processGO:00425921420.040
Human
establishment of mitotic spindle localizationGO:0040001120.040
positive regulation of gene expressionGO:0010628710.040
Human Mouse Rat
positive regulation of biological processGO:00485182530.039
Human Mouse Rat
regulation of hematopoietic progenitor cell differentiationGO:190153210.039
Human
neuron projection developmentGO:00311751800.039
neuroblast proliferationGO:000740520.039
single organism intracellular transportGO:1902582250.037
response to organic cyclic compoundGO:0014070510.036
Mouse
protein complex subunit organizationGO:0071822460.036
response to molecule of bacterial originGO:0002237140.035
Human
recombinational repairGO:000072510.035
negative regulation of programmed cell deathGO:0043069580.035
Mouse
digestive tract morphogenesisGO:00485462310.034
hematopoietic stem cell homeostasisGO:006148420.033
cell death in response to oxidative stressGO:003647320.033
response to external biotic stimulusGO:0043207970.033
Human
protein acetylationGO:000647320.033
positive regulation of nucleobase containing compound metabolic processGO:0045935690.033
Human Mouse Rat
regulation of cell cycleGO:0051726520.032
negative regulation of macromolecule metabolic processGO:0010605760.032
Human
peptidyl lysine acetylationGO:001839420.032
rna polyadenylationGO:004363120.031
response to oxygen containing compoundGO:1901700550.031
Human
establishment of cell polarityGO:0030010180.031
regulation of cell maturationGO:190342910.031
gamete generationGO:0007276330.031
Mouse
double strand break repair via homologous recombinationGO:000072410.031
intracellular signal transductionGO:0035556850.031
regulation of cellular component organizationGO:0051128860.030
cellular response to organic substanceGO:00713101050.030
Human
regulation of response to stressGO:0080134360.030
mitotic dna damage checkpointGO:004477340.030
actin filament based processGO:0030029640.030
negative regulation of macromolecule biosynthetic processGO:0010558480.029
Human
regulation of cell shapeGO:000836010.029
negative regulation of nitrogen compound metabolic processGO:0051172590.029
Human
negative regulation of cellular biosynthetic processGO:0031327550.029
Human
cell cycleGO:0007049930.029
negative regulation of apoptotic processGO:0043066550.028
Mouse
regulation of developmental processGO:00507932470.028
Human
actomyosin structure organizationGO:0031032530.028
positive regulation of molecular functionGO:0044093330.028
Human Mouse
fertilizationGO:000956630.027
regulation of heart growthGO:006042020.027
regulation of transcription from rna polymerase ii promoterGO:00063571140.027
Human Mouse
cell cycle g2 m phase transitionGO:004483940.027
microtubule polymerizationGO:004678520.027
cellular component disassemblyGO:002241110.026
epithelial cell morphogenesisGO:000338220.026
heart developmentGO:00075073130.026
mrna metabolic processGO:0016071200.026
organelle fissionGO:0048285230.026
cellular nitrogen compound catabolic processGO:0044270150.026
cellular response to endogenous stimulusGO:0071495680.025
regulation of reproductive processGO:200024140.025
regulation of programmed cell deathGO:00430671010.025
Mouse
regulation of phosphate metabolic processGO:0019220430.025
regulation of molecular functionGO:0065009700.025
Human Mouse
phosphorylationGO:0016310690.024
positive chemotaxisGO:005091850.023
Human
microtubule cytoskeleton organizationGO:0000226330.023
protein acylationGO:004354330.023
mitotic cell cycle embryonicGO:004544820.023
telomere organizationGO:003220010.023
protein polymerizationGO:005125840.022
microtubule organizing center organizationGO:003102310.022
phagocytosisGO:000690930.022
hematopoietic progenitor cell differentiationGO:0002244230.022
Human
negative regulation of leukocyte differentiationGO:190210610.022
regulation of meiotic cell cycleGO:005144510.022
positive regulation of cellular catabolic processGO:003133130.022
regulation of cellular response to oxidative stressGO:190040720.022
positive regulation of gastrulationGO:200054320.022
neuron projection morphogenesisGO:00488121610.022
sexual reproductionGO:0019953360.022
Mouse
homeostasis of number of cellsGO:0048872620.021
Human
mitotic dna integrity checkpointGO:004477440.021
adult behaviorGO:003053420.021
determination of bilateral symmetryGO:00098552040.021
aromatic compound catabolic processGO:0019439150.021
multi organism reproductive processGO:0044703360.021
Mouse
negative regulation of cell deathGO:0060548600.021
Mouse
cell divisionGO:0051301200.021
protein metabolic processGO:00195381830.021
meiotic nuclear divisionGO:000712640.021
negative regulation of myeloid cell differentiationGO:004563810.020
positive regulation of macromolecule biosynthetic processGO:0010557590.020
Human Mouse Rat
cell projection morphogenesisGO:00488582440.020
response to hormoneGO:0009725480.020
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
Mouse
spliceosomal snrnp assemblyGO:000038720.020
microtubule cytoskeleton organization involved in mitosisGO:190285010.020
protein sumoylationGO:001692520.020
positive regulation of nucleic acid templated transcriptionGO:1903508570.019
Human Mouse Rat
embryonic skeletal system morphogenesisGO:0048704930.019
regulation of stem cell proliferationGO:007209120.019
pharyngeal muscle developmentGO:004328240.019
mrna catabolic processGO:000640260.019
single fertilizationGO:000733830.019
mitotic cell cycle processGO:1903047480.019
nuclear transportGO:005116940.019
erythrocyte homeostasisGO:0034101550.019
Human
protein complex biogenesisGO:0070271300.019
negative regulation of biosynthetic processGO:0009890550.018
Human
protein complex disassemblyGO:004324110.018
cellular response to external stimulusGO:007149620.018
single organism transportGO:00447652060.018
cognitionGO:005089010.018
positive regulation of signalingGO:0023056560.018
macromolecular complex assemblyGO:0065003350.018
phosphate containing compound metabolic processGO:00067961080.018
positive regulation of cell communicationGO:0010647560.018
spindle localizationGO:0051653120.018
response to unfolded proteinGO:000698620.017
response to endogenous stimulusGO:0009719830.017
Mouse
negative regulation of transcription dna templatedGO:0045892450.017
Human
single organism behaviorGO:0044708240.017
cell morphogenesis involved in differentiationGO:00009041950.016
reproductive processGO:0022414400.016
Mouse
immune system developmentGO:00025201910.016
Human
mitotic nuclear divisionGO:0007067180.016
hemopoiesisGO:00300971830.016
Human
regulation of growth rateGO:004000910.016
meiotic cell cycle processGO:190304630.016
carboxylic acid metabolic processGO:0019752220.016
response to lipopolysaccharideGO:0032496130.016
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.016
regulation of alternative mrna splicing via spliceosomeGO:000038110.016
spliceosomal complex assemblyGO:000024510.016
axonogenesisGO:00074091520.016
positive regulation of rna metabolic processGO:0051254590.015
Human Mouse Rat
mrna 3 end processingGO:003112420.015
regulation of localizationGO:00328791040.015
mitotic spindle organizationGO:000705250.015
positive regulation of biosynthetic processGO:0009891680.015
Human Mouse Rat
agingGO:000756820.015
nuclear divisionGO:0000280230.015
rna 3 end processingGO:003112320.015
macromolecule modificationGO:00434121110.015
amine metabolic processGO:000930820.015
positive regulation of macromolecule metabolic processGO:0010604930.014
Human Mouse Rat
eye developmentGO:00016542770.014
centrosome cycleGO:000709810.014
regulation of apoptotic signaling pathwayGO:2001233120.014
Mouse
regulation of protein bindingGO:004339330.014
nucleoside monophosphate catabolic processGO:000912540.014
positive regulation of gtpase activityGO:004354710.014
embryonic digestive tract morphogenesisGO:004855730.014
muscle organ developmentGO:00075171010.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
regulation of cell cycle processGO:0010564200.014
b cell differentiationGO:003018310.014
cell cycle processGO:0022402530.014
myofibril assemblyGO:0030239480.014
atp catabolic processGO:000620040.014
organic cyclic compound catabolic processGO:1901361150.013
negative regulation of mrna metabolic processGO:190331230.013
dna catabolic processGO:000630810.013
mesenchymal cell developmentGO:0014031780.013
response to virusGO:0009615210.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
Human Mouse Rat
lipid storageGO:001991510.013
digestive tract developmentGO:00485652650.013
regulation of cellular component biogenesisGO:0044087120.013
oxoacid metabolic processGO:0043436310.013
nucleobase containing compound transportGO:001593120.013
protein import into nucleusGO:000660630.013
dna repairGO:000628160.013
Human
alternative mrna splicing via spliceosomeGO:000038010.013
protein homooligomerizationGO:005126030.013
internal peptidyl lysine acetylationGO:001839320.012
nucleobase containing compound catabolic processGO:0034655150.012
cellular response to extracellular stimulusGO:003166820.012
positive regulation of nucleotide catabolic processGO:003081310.012
striated muscle tissue developmentGO:00147061100.012
cellular response to lipidGO:0071396390.012
Human
regulation of gene expression epigeneticGO:0040029110.012
internal protein amino acid acetylationGO:000647520.012
sex differentiationGO:000754850.012
Mouse
regulation of cellular amino acid metabolic processGO:000652100.012
male gamete generationGO:004823270.012
Mouse
positive regulation of catalytic activityGO:0043085250.012
Human
behaviorGO:0007610740.012
negative regulation of apoptotic signaling pathwayGO:2001234100.012
Mouse
cellular protein modification processGO:00064641000.012
immune system processGO:00023762410.011
Human
positive regulation of embryonic developmentGO:004001930.011
positive regulation of map kinase activityGO:004340630.011
regulation of organ morphogenesisGO:2000027350.011
regulation of mrna processingGO:005068430.011
organic acid metabolic processGO:0006082310.011
regulation of phosphorylationGO:0042325260.011
regulation of cellular ketone metabolic processGO:001056570.011
cellular macromolecular complex assemblyGO:0034622240.011
small molecule metabolic processGO:0044281770.011
negative regulation of multi organism processGO:004390130.011
organic substance catabolic processGO:1901575280.011
response to ketoneGO:190165410.011
regulation of oocyte developmentGO:006028130.010
regulation of bindingGO:005109830.010
Human Mouse
cell morphogenesisGO:00009022890.010
modification dependent macromolecule catabolic processGO:004363230.010
regionalizationGO:00030022740.010
regulation of apoptotic processGO:0042981980.010
Mouse
positive regulation of metabolic processGO:00098931080.010
Human Mouse Rat
intracellular transportGO:0046907320.010
lipid homeostasisGO:005508830.010

hmgb2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.017
acquired metabolic diseaseDOID:006015800.015
carbohydrate metabolism diseaseDOID:005001300.015
disease of metabolismDOID:001466700.015
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012