IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

abce1

ATP-binding cassette, sub-family E (OABP), member 1

(Aliases: wu:fe47b01,zgc:56045,wu:fb34c09,zgc:111906,wu:fi09g07,MGC56045)

ZFIN: ZDB-GENE-040426-1995
Entrez: 406324
Ensembl: ENSDARG00000007216
UniProtKB: Q6TNW3

Process Predictions
Disease Predictions

abce1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
larval development	GO:0002164	2	0.974	Worm
embryo development ending in birth or egg hatching	GO:0009792	271	0.648	Worm
macromolecule biosynthetic process	GO:0009059	227	0.453	Yeast Fly
aging	GO:0007568	2	0.374
multicellular organism growth	GO:0035264	4	0.333
protein metabolic process	GO:0019538	183	0.280	Yeast Fly
locomotion	GO:0040011	313	0.244	Worm
regulation of metabolic process	GO:0019222	359	0.228	Yeast
regulation of multicellular organism growth	GO:0040014	4	0.220
regulation of biosynthetic process	GO:0009889	250	0.211	Yeast
organic substance biosynthetic process	GO:1901576	289	0.188	Yeast Fly
nitrogen compound metabolic process	GO:0006807	319	0.178
cellular biosynthetic process	GO:0044249	286	0.147	Yeast Fly
head development	GO:0060322	303	0.142
reproduction	GO:0000003	40	0.141	Worm
biosynthetic process	GO:0009058	294	0.131	Yeast Fly
spindle assembly	GO:0051225	2	0.123
cellular protein metabolic process	GO:0044267	129	0.115	Yeast Fly
nucleic acid metabolic process	GO:0090304	244	0.103
small molecule metabolic process	GO:0044281	77	0.092
organic cyclic compound metabolic process	GO:1901360	301	0.086
chordate embryonic development	GO:0043009	271	0.084
regulation of multicellular organismal process	GO:0051239	277	0.084
regulation of macromolecule metabolic process	GO:0060255	317	0.082	Yeast
cellular nitrogen compound metabolic process	GO:0034641	290	0.080
signal transduction	GO:0007165	455	0.078
gamete generation	GO:0007276	33	0.078
single organism metabolic process	GO:0044710	217	0.077
cellular macromolecule biosynthetic process	GO:0034645	224	0.076	Yeast Fly
death	GO:0016265	121	0.074	Fly
regulation of signal transduction	GO:0009966	225	0.071
rna metabolic process	GO:0016070	219	0.061
pyrimidine containing compound biosynthetic process	GO:0072528	2	0.058
translation	GO:0006412	5	0.058	Yeast Fly
regulation of gene expression	GO:0010468	265	0.058	Yeast
heterocycle metabolic process	GO:0046483	290	0.057
cation transport	GO:0006812	81	0.054
cellular macromolecule metabolic process	GO:0044260	391	0.053	Yeast Fly
protein complex assembly	GO:0006461	30	0.052
cellular aromatic compound metabolic process	GO:0006725	295	0.049
embryonic skeletal system morphogenesis	GO:0048704	93	0.049
sensory organ development	GO:0007423	393	0.049
embryonic cranial skeleton morphogenesis	GO:0048701	90	0.048
digestive tract development	GO:0048565	265	0.046
cell cell recognition	GO:0009988	1	0.045
regulation of endopeptidase activity	GO:0052548	23	0.043
regulation of cell communication	GO:0010646	232	0.042
skeletal system development	GO:0001501	181	0.042
cellular response to chemical stimulus	GO:0070887	157	0.041	Yeast
protein acetylation	GO:0006473	2	0.041
digestive system development	GO:0055123	289	0.040
toxin transport	GO:1901998	2	0.038
nucleocytoplasmic transport	GO:0006913	4	0.038	Yeast
lipid storage	GO:0019915	1	0.037
cell motility	GO:0048870	244	0.037
organelle localization	GO:0051640	49	0.037	Yeast
response to chemical	GO:0042221	320	0.036	Yeast
regulation of primary metabolic process	GO:0080090	311	0.036	Yeast
regulation of apoptotic process	GO:0042981	98	0.036	Fly
macromolecular complex assembly	GO:0065003	35	0.036
cellular amino acid metabolic process	GO:0006520	7	0.034
spindle assembly involved in mitosis	GO:0090307	1	0.034
positive regulation of catabolic process	GO:0009896	4	0.034
positive regulation of cellular catabolic process	GO:0031331	3	0.034
positive regulation of biological process	GO:0048518	253	0.033	Yeast
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.033
gene silencing by rna	GO:0031047	4	0.033
cell migration	GO:0016477	237	0.033
cell death	GO:0008219	121	0.033	Fly
single organism organelle organization	GO:1902589	199	0.031	Yeast
gtp catabolic process	GO:0006184	2	0.031
positive regulation of translation	GO:0045727	1	0.031	Yeast
mesenchymal cell development	GO:0014031	78	0.031
heterocycle biosynthetic process	GO:0018130	215	0.030
vasculature development	GO:0001944	278	0.030
ribosomal small subunit biogenesis	GO:0042274	2	0.030
mononuclear cell proliferation	GO:0032943	1	0.030
regulation of response to stimulus	GO:0048583	269	0.029
multi organism process	GO:0051704	134	0.029
regulation of cellular metabolic process	GO:0031323	320	0.028	Yeast
apoptotic process	GO:0006915	116	0.027	Fly
maintenance of location	GO:0051235	4	0.026
gene expression	GO:0010467	252	0.026	Yeast Fly
oxoacid metabolic process	GO:0043436	31	0.025
cell surface receptor signaling pathway	GO:0007166	325	0.025
camera type eye development	GO:0043010	222	0.025
embryonic organ development	GO:0048568	381	0.025
aromatic compound biosynthetic process	GO:0019438	217	0.025
regulation of protein catabolic process	GO:0042176	1	0.024
establishment of localization	GO:0051234	244	0.024	Yeast
skeletal system morphogenesis	GO:0048705	102	0.024
protein complex subunit organization	GO:0071822	46	0.024	Yeast
retina development in camera type eye	GO:0060041	146	0.024
transport	GO:0006810	220	0.023	Yeast
positive regulation of cellular process	GO:0048522	201	0.023	Yeast
cellular component assembly	GO:0022607	170	0.023
growth	GO:0040007	174	0.023	Fly
embryonic skeletal system development	GO:0048706	97	0.023
regulation of growth	GO:0040008	42	0.022
protein modification process	GO:0036211	100	0.022
cellular response to external stimulus	GO:0071496	2	0.021
nucleobase containing compound metabolic process	GO:0006139	274	0.021
negative regulation of gene expression	GO:0010629	65	0.021
endoplasmic reticulum unfolded protein response	GO:0030968	2	0.021
regulation of developmental process	GO:0050793	247	0.021
nucleobase containing small molecule metabolic process	GO:0055086	32	0.021
eye development	GO:0001654	277	0.021
regulation of signaling	GO:0023051	235	0.020
organelle assembly	GO:0070925	110	0.020
positive regulation of biosynthetic process	GO:0009891	68	0.020	Yeast
system process	GO:0003008	185	0.020
organonitrogen compound metabolic process	GO:1901564	74	0.020
ribonucleoprotein complex biogenesis	GO:0022613	13	0.020	Yeast
negative regulation of protein phosphorylation	GO:0001933	4	0.019
mitotic g2 dna damage checkpoint	GO:0007095	3	0.019
post embryonic development	GO:0009791	7	0.019	Worm
immune system process	GO:0002376	241	0.019
cellular response to organic substance	GO:0071310	105	0.019
lymphocyte proliferation	GO:0046651	1	0.019
response to unfolded protein	GO:0006986	2	0.019
endocytosis	GO:0006897	16	0.018
negative regulation of macromolecule metabolic process	GO:0010605	76	0.018
regulation of macromolecule biosynthetic process	GO:0010556	225	0.018	Yeast
striated muscle cell differentiation	GO:0051146	129	0.018
protein complex biogenesis	GO:0070271	30	0.018
g2 dna damage checkpoint	GO:0031572	3	0.017
regulation of developmental growth	GO:0048638	38	0.017
meiotic cell cycle process	GO:1903046	3	0.017
nucleoside triphosphate biosynthetic process	GO:0009142	2	0.017
carbohydrate derivative metabolic process	GO:1901135	61	0.017
developmental growth	GO:0048589	166	0.017
regulation of protein modification by small protein conjugation or removal	GO:1903320	3	0.017
multicellular organismal reproductive process	GO:0048609	35	0.017
single organism reproductive process	GO:0044702	40	0.017	Worm
posttranscriptional regulation of gene expression	GO:0010608	14	0.017	Yeast
intracellular transport	GO:0046907	32	0.016	Yeast
cell morphogenesis	GO:0000902	289	0.016
meiotic spindle organization	GO:0000212	1	0.016
regulation of establishment of protein localization	GO:0070201	4	0.016
organelle organization	GO:0006996	227	0.016	Yeast
striated muscle cell development	GO:0055002	108	0.016
cellular response to extracellular stimulus	GO:0031668	2	0.015
digestive tract morphogenesis	GO:0048546	231	0.015
single organism biosynthetic process	GO:0044711	71	0.015
post embryonic morphogenesis	GO:0009886	4	0.015
multicellular organism reproduction	GO:0032504	35	0.015
carboxylic acid metabolic process	GO:0019752	22	0.014
intracellular signal transduction	GO:0035556	85	0.014
purine ribonucleoside monophosphate catabolic process	GO:0009169	4	0.014
cellular response to stress	GO:0033554	62	0.014	Yeast
establishment of protein localization to organelle	GO:0072594	4	0.014
negative regulation of cell death	GO:0060548	60	0.014	Fly
ncrna metabolic process	GO:0034660	12	0.013
maturation of ssu rrna	GO:0030490	1	0.013
g1 s transition of mitotic cell cycle	GO:0000082	1	0.013
regulation of binding	GO:0051098	3	0.013
positive regulation of cytosolic calcium ion concentration	GO:0007204	4	0.013
macromolecular complex disassembly	GO:0032984	1	0.013	Yeast
reproductive process	GO:0022414	40	0.013	Worm
programmed cell death	GO:0012501	119	0.013	Fly
fin regeneration	GO:0031101	51	0.013
localization of cell	GO:0051674	244	0.013
response to oxygen containing compound	GO:1901700	55	0.013
meiotic nuclear division	GO:0007126	4	0.013
enzyme linked receptor protein signaling pathway	GO:0007167	106	0.013
heart rudiment development	GO:0003313	8	0.013
cellular response to unfolded protein	GO:0034620	2	0.012
cellular protein modification process	GO:0006464	100	0.012
mrna processing	GO:0006397	14	0.012
cellular component biogenesis	GO:0044085	178	0.012	Yeast
regulation of anatomical structure morphogenesis	GO:0022603	130	0.012
single organism localization	GO:1902578	225	0.012	Yeast
double strand break repair	GO:0006302	3	0.012
protein complex disassembly	GO:0043241	1	0.012	Yeast
body morphogenesis	GO:0010171	16	0.012	Worm
organic acid metabolic process	GO:0006082	31	0.012
protein acylation	GO:0043543	3	0.012
tube morphogenesis	GO:0035239	349	0.012
peptidyl lysine acetylation	GO:0018394	2	0.012
positive regulation of response to stimulus	GO:0048584	80	0.012
nucleoside monophosphate catabolic process	GO:0009125	4	0.012
fertilization	GO:0009566	3	0.011
cellular protein catabolic process	GO:0044257	4	0.011
atp catabolic process	GO:0006200	4	0.011
myofibril assembly	GO:0030239	48	0.011
cellular component disassembly	GO:0022411	1	0.011	Yeast
cellular catabolic process	GO:0044248	27	0.011
organic cyclic compound biosynthetic process	GO:1901362	223	0.011
regulation of biological quality	GO:0065008	263	0.011
positive regulation of gene expression	GO:0010628	71	0.011	Yeast
gene silencing	GO:0016458	4	0.011
leukocyte proliferation	GO:0070661	1	0.011
positive regulation of macromolecule metabolic process	GO:0010604	93	0.011	Yeast
guanosine containing compound catabolic process	GO:1901069	2	0.011
regulation of cellular biosynthetic process	GO:0031326	245	0.010	Yeast
embryonic organ morphogenesis	GO:0048562	274	0.010
mitotic nuclear division	GO:0007067	18	0.010
brain development	GO:0007420	293	0.010
internal protein amino acid acetylation	GO:0006475	2	0.010
cellular response to nutrient levels	GO:0031669	2	0.010
tissue remodeling	GO:0048771	4	0.010

abce1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.085
nervous system disease	DOID:863	0.075
neuromuscular disease	DOID:440	0.011
charcot marie tooth disease type 2	DOID:0050539	0.011
charcot marie tooth disease	DOID:10595	0.011
neuropathy	DOID:870	0.011

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