Danio rerio

91 known processes

lzts2a

leucine zipper, putative tumor suppressor 2a

(Aliases: lzts2,si:dkey-250a11.1)

lzts2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vasculature developmentGO:00019442780.652
cell surface receptor signaling pathwayGO:00071663250.631
signal transductionGO:00071654550.627
morphogenesis of an epitheliumGO:00020093330.369
regulation of response to stimulusGO:00485832690.339
regulation of nucleic acid templated transcriptionGO:19035062130.286
blood vessel developmentGO:00015682460.285
regulation of cellular macromolecule biosynthetic processGO:20001122220.279
regulation of reproductive processGO:200024140.228
rna biosynthetic processGO:00327741810.223
regulation of metabolic processGO:00192223590.218
chordate embryonic developmentGO:00430092710.217
angiogenesisGO:00015251580.211
cellular nitrogen compound biosynthetic processGO:00442712180.210
biosynthetic processGO:00090582940.206
head developmentGO:00603223030.203
blood vessel morphogenesisGO:00485142160.197
macromolecule biosynthetic processGO:00090592270.189
regulation of multicellular organismal developmentGO:20000262230.184
negative regulation of cellular processGO:00485232830.183
nitrogen compound metabolic processGO:00068073190.182
nephron morphogenesisGO:007202820.178
regulation of cell differentiationGO:00455951420.175
epithelial tube morphogenesisGO:00605621480.171
wnt signaling pathwayGO:0016055800.158
cell morphogenesis involved in neuron differentiationGO:00486671630.155
cellular nitrogen compound metabolic processGO:00346412900.150
hematopoietic or lymphoid organ developmentGO:00485341910.148
regulation of cell communicationGO:00106462320.141
skeletal system developmentGO:00015011810.140
hemopoiesisGO:00300971830.139
negative regulation of biological processGO:00485193040.137
regulation of signalingGO:00230512350.137
response to external stimulusGO:00096052640.136
heart morphogenesisGO:00030071560.135
cellular macromolecule biosynthetic processGO:00346452240.134
regulation of transcription dna templatedGO:00063552130.129
cell motilityGO:00488702440.129
organic substance biosynthetic processGO:19015762890.129
convergent extensionGO:00600261180.126
protein localization to nucleusGO:003450430.126
cellular biosynthetic processGO:00442492860.125
negative regulation of response to stimulusGO:00485851040.122
eye developmentGO:00016542770.118
negative regulation of cell communicationGO:0010648960.114
sequestering of calcium ionGO:005120830.113
nucleic acid metabolic processGO:00903042440.111
cartilage developmentGO:0051216960.110
negative regulation of signalingGO:0023057960.110
digestive system developmentGO:00551232890.108
locomotionGO:00400113130.105
cellular component morphogenesisGO:00329893360.103
immune system processGO:00023762410.102
negative regulation of nucleic acid templated transcriptionGO:1903507450.101
regulation of primary metabolic processGO:00800903110.101
heterocycle metabolic processGO:00464832900.101
negative regulation of sequestering of calcium ionGO:005128340.100
regulation of neurogenesisGO:0050767870.099
embryonic heart tube developmentGO:00350501330.095
convergent extension involved in gastrulationGO:0060027710.094
brain developmentGO:00074202930.094
cell migrationGO:00164772370.093
cell recognitionGO:0008037190.092
nephron tubule morphogenesisGO:007207810.089
cellular macromolecule metabolic processGO:00442603910.089
optic placode formationGO:000174340.088
cell growthGO:0016049570.087
sensory organ developmentGO:00074233930.082
renal tubule morphogenesisGO:006133310.080
eye field cell fate commitment involved in camera type eye formationGO:006089830.080
tube morphogenesisGO:00352393490.079
synaptic target recognitionGO:000803910.077
optic placode formation involved in camera type eye formationGO:004661930.077
response to chemicalGO:00422213200.076
regionalizationGO:00030022740.074
regulation of gene expressionGO:00104682650.073
skeletal system morphogenesisGO:00487051020.072
regulation of canonical wnt signaling pathwayGO:0060828340.071
cell morphogenesis involved in differentiationGO:00009041950.069
hepatocyte proliferationGO:007257420.068
positive regulation of cellular processGO:00485222010.068
sensory organ morphogenesisGO:00905962000.068
cell part morphogenesisGO:00329902460.066
enzyme linked receptor protein signaling pathwayGO:00071671060.066
embryonic organ developmentGO:00485683810.065
chemotaxisGO:00069351040.065
protein importGO:001703830.065
regulation of macromolecule metabolic processGO:00602553170.065
negative chemotaxisGO:005091910.063
regulation of rna metabolic processGO:00512522240.062
embryonic heart tube morphogenesisGO:00031431080.060
embryonic cranial skeleton morphogenesisGO:0048701900.059
canonical wnt signaling pathwayGO:0060070480.059
synaptic transmission cholinergicGO:000727140.059
regulation of meiotic cell cycleGO:005144510.059
regulation of signal transductionGO:00099662250.058
regulation of peptidyl tyrosine phosphorylationGO:005073010.056
regulation of rna biosynthetic processGO:20011412130.055
heterocycle biosynthetic processGO:00181302150.055
cellular response to nutrient levelsGO:003166920.055
muscle cell differentiationGO:00426921390.055
neuron differentiationGO:00301823530.055
digestive tract developmentGO:00485652650.054
gene expressionGO:00104672520.054
axon developmentGO:00615641660.054
organelle organizationGO:00069962270.053
central nervous system developmentGO:00074173870.053
regulation of stem cell differentiationGO:200073640.053
nucleobase containing compound biosynthetic processGO:00346542050.052
heart loopingGO:0001947940.052
retinal ganglion cell axon guidanceGO:0031290350.052
dorsal ventral pattern formationGO:00099531250.051
positive regulation of canonical wnt signaling pathwayGO:009026340.051
immune system developmentGO:00025201910.051
regulation of cellular metabolic processGO:00313233200.050
regulation of cell developmentGO:00602841000.050
developmental growthGO:00485891660.050
regulation of nitrogen compound metabolic processGO:00511712510.049
negative regulation of wnt signaling pathwayGO:0030178300.049
amine metabolic processGO:000930820.049
developmental cell growthGO:0048588520.049
mesenchyme developmentGO:00604851270.049
growthGO:00400071740.049
taxisGO:00423301090.048
transportGO:00068102200.048
neuron developmentGO:00486662620.048
sequestering of metal ionGO:005123830.047
regulation of cellular response to growth factor stimulusGO:0090287350.046
regulation of multicellular organism growthGO:004001440.045
patterning of blood vesselsGO:0001569150.045
organic cyclic compound metabolic processGO:19013603010.043
protein modification processGO:00362111000.043
response to growth factorGO:0070848390.042
intracellular signal transductionGO:0035556850.042
embryonic organ morphogenesisGO:00485622740.041
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.041
nephron epithelium morphogenesisGO:007208810.041
regulation of carbohydrate metabolic processGO:000610940.040
negative regulation of signal transductionGO:0009968940.040
negative regulation of anterior neural cell fate commitment of the neural plateGO:002200110.040
organic cyclic compound biosynthetic processGO:19013622230.040
negative regulation of reproductive processGO:200024230.040
transcription dna templatedGO:00063511810.040
extrinsic apoptotic signaling pathwayGO:009719130.040
specification of symmetryGO:00097992040.039
regulation of cellular carbohydrate metabolic processGO:001067540.039
negative regulation of dna replicationGO:000815620.039
regulation of stem cell proliferationGO:007209120.038
cellular response to growth factor stimulusGO:0071363390.038
epithelial cell proliferation involved in liver morphogenesisGO:007257520.038
positive regulation of biological processGO:00485182530.037
embryonic eye morphogenesisGO:0048048300.037
primary neural tube formationGO:001402010.037
regulation of multicellular organismal processGO:00512392770.037
cellular protein metabolic processGO:00442671290.037
cell morphogenesisGO:00009022890.037
regulation of sequestering of calcium ionGO:005128240.036
cartilage condensationGO:000150230.036
regulation of cellular amine metabolic processGO:003323800.036
aromatic compound biosynthetic processGO:00194382170.036
muscle cell migrationGO:001481240.036
embryonic skeletal system developmentGO:0048706970.036
regulation of developmental processGO:00507932470.036
odontogenesis of dentin containing toothGO:004247510.036
regulation of extrinsic apoptotic signaling pathwayGO:200123630.036
establishment of localization in cellGO:0051649770.035
cellular aromatic compound metabolic processGO:00067252950.035
cell projection organizationGO:00300302840.035
stem cell proliferationGO:007208940.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.035
regulation of cellular component organizationGO:0051128860.035
transcription from rna polymerase ii promoterGO:0006366800.034
embryonic hemopoiesisGO:0035162530.034
localization of cellGO:00516742440.034
nucleobase containing compound metabolic processGO:00061392740.034
myeloid cell differentiationGO:0030099860.034
negative regulation of axon extension involved in axon guidanceGO:004884310.033
regulation of axon extensionGO:0030516240.033
positive regulation of response to stimulusGO:0048584800.033
vasculogenesisGO:0001570410.033
development of primary female sexual characteristicsGO:004654540.033
small molecule metabolic processGO:0044281770.033
cell projection morphogenesisGO:00488582440.033
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.033
connective tissue developmentGO:0061448990.032
negative regulation of macromolecule biosynthetic processGO:0010558480.032
regulation of neuron differentiationGO:0045664560.032
phosphorylationGO:0016310690.031
axon guidanceGO:0007411860.031
positive regulation of cytosolic calcium ion concentrationGO:000720440.031
neuroblast proliferationGO:000740520.031
protein targeting to nucleusGO:004474430.030
dorsal convergenceGO:0060030140.030
negative regulation of macromolecule metabolic processGO:0010605760.030
neuron projection developmentGO:00311751800.030
cellular response to organic substanceGO:00713101050.029
regulation of epithelial to mesenchymal transitionGO:001071730.029
cellular component movementGO:00069283350.029
cellular response to chemical stimulusGO:00708871570.029
larval developmentGO:000216420.028
cellular amine metabolic processGO:004410620.028
regulation of cellular biosynthetic processGO:00313262450.028
oxoacid metabolic processGO:0043436310.028
regulation of chondrocyte differentiationGO:003233010.028
nucleic acid templated transcriptionGO:00976591810.027
inner ear developmentGO:00488391260.027
positive regulation of cell activationGO:005086710.027
protein metabolic processGO:00195381830.027
regulation of cellular amino acid metabolic processGO:000652100.027
regulation of transcription from rna polymerase ii promoterGO:00063571140.027
macromolecule modificationGO:00434121110.027
neuron projection regenerationGO:0031102160.027
embryonic skeletal system morphogenesisGO:0048704930.027
gastrulation with mouth forming secondGO:0001702440.027
ear developmentGO:00435831270.027
regulation of anterior head developmentGO:200074220.027
single organism nuclear importGO:190259330.026
multicellular organismal metabolic processGO:004423620.026
motor neuron axon guidanceGO:0008045230.026
hindbrain developmentGO:0030902910.026
cellular protein modification processGO:00064641000.026
neuron projection extensionGO:1990138450.026
regulation of nervous system developmentGO:0051960900.026
negative regulation of dna metabolic processGO:005105340.025
regulation of anatomical structure sizeGO:0090066330.025
system processGO:00030081850.025
spindle localizationGO:0051653120.025
organic acid metabolic processGO:0006082310.025
thrombocyte differentiationGO:000257440.025
pancreas developmentGO:0031016840.024
adult behaviorGO:003053420.024
glycoprotein biosynthetic processGO:0009101210.024
single organism organelle organizationGO:19025891990.024
response to drugGO:004249330.024
negative regulation of homeostatic processGO:003284550.024
cellular component assembly involved in morphogenesisGO:00109271070.024
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.024
single organism cellular localizationGO:1902580460.024
stem cell developmentGO:0048864820.024
regulation of growthGO:0040008420.024
adherens junction organizationGO:003433240.024
cellular amino acid metabolic processGO:000652070.024
positive regulation of cellular amine metabolic processGO:003324000.024
regulation of dna replicationGO:000627530.024
negative regulation of metabolic processGO:0009892860.023
nuclear transportGO:005116940.023
embryonic skeletal joint developmentGO:007249830.023
common bile duct developmentGO:0061009130.023
pharyngeal system developmentGO:0060037180.023
oocyte maturationGO:000155640.023
epithelial tube formationGO:0072175190.023
morphogenesis of embryonic epitheliumGO:0016331300.023
post embryonic organ developmentGO:004856940.023
spinal cord anterior posterior patterningGO:002151210.023
regulation of synapse assemblyGO:005196330.023
cellular response to endogenous stimulusGO:0071495680.023
cellular carbohydrate metabolic processGO:004426240.022
regulation of biosynthetic processGO:00098892500.022
positive regulation of catabolic processGO:000989640.022
developmental growth involved in morphogenesisGO:0060560860.022
organelle localizationGO:0051640490.022
gall bladder developmentGO:006101010.022
female gonad developmentGO:000858540.022
positive regulation of cellular amino acid metabolic processGO:004576400.021
eye morphogenesisGO:00485921440.021
regenerationGO:0031099910.021
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.021
neuron projection guidanceGO:0097485860.021
cellular ketone metabolic processGO:0042180110.021
camera type eye morphogenesisGO:00485931080.021
synaptic growth at neuromuscular junctionGO:005112420.020
cellular response to starvationGO:000926710.020
cytosolic calcium ion transportGO:006040130.020
forebrain neuron differentiationGO:0021879140.020
rna metabolic processGO:00160702190.020
microtubule based processGO:0007017600.020
female sex differentiationGO:004666040.020
establishment of protein localization to organelleGO:007259440.020
neuron projection morphogenesisGO:00488121610.020
regulation of localizationGO:00328791040.020
multicellular organism growthGO:003526440.020
cellular chemical homeostasisGO:0055082170.020
camera type eye developmentGO:00430102220.020
regulation of neuron projection developmentGO:0010975400.020
embryo development ending in birth or egg hatchingGO:00097922710.019
regulation of anatomical structure morphogenesisGO:00226031300.019
mesenchymal cell developmentGO:0014031780.019
negative regulation of cell cycle processGO:001094890.019
anterior head developmentGO:009706520.019
positive regulation of multicellular organismal processGO:0051240520.019
cognitionGO:005089010.019
autonomic nervous system developmentGO:0048483190.019
smoothened signaling pathwayGO:0007224300.019
mediolateral intercalationGO:006003130.019
ceramide biosynthetic processGO:004651310.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
organonitrogen compound metabolic processGO:1901564740.019
tube formationGO:0035148250.018
response to nutrientGO:000758430.018
positive regulation of cellular catabolic processGO:003133130.018
negative regulation of intracellular transportGO:003238730.018
regulation of cell growthGO:0001558290.018
negative regulation of axon guidanceGO:190266810.018
regulation of cellular ketone metabolic processGO:001056570.018
spinal cord patterningGO:002151160.017
regulation of wnt signaling pathwayGO:0030111530.017
organelle assemblyGO:00709251100.017
mitotic g2 dna damage checkpointGO:000709530.017
glycoprotein metabolic processGO:0009100230.017
negative regulation of cellular metabolic processGO:0031324770.017
cartilage morphogenesisGO:0060536130.017
establishment of mitotic spindle localizationGO:0040001120.017
response to stressGO:00069502630.017
determination of bilateral symmetryGO:00098552040.017
mesenchymal cell differentiationGO:0048762870.016
epithalamus developmentGO:0021538100.016
regulation of cell morphogenesisGO:0022604420.016
phosphate containing compound metabolic processGO:00067961080.016
positive regulation of transportGO:005105020.016
regulation of cell sizeGO:0008361290.016
fin developmentGO:0033333770.016
metal ion homeostasisGO:0055065260.016
actin cytoskeleton organizationGO:0030036630.016
regulation of behaviorGO:0050795240.016
determination of heart left right asymmetryGO:00613711170.016
determination of ventral identityGO:0048264210.016
ectodermal placode developmentGO:0071696370.016
kidney developmentGO:0001822920.016
neural tube developmentGO:0021915620.016
negative regulation of cell differentiationGO:0045596460.016
negative regulation of gene expressionGO:0010629650.015
ectoderm developmentGO:000739890.015
regulation of production of molecular mediator of immune responseGO:000270010.015
regulation of extent of cell growthGO:0061387290.015
protein phosphorylationGO:0006468470.015
determination of left right symmetryGO:00073681790.015
thymus developmentGO:0048538100.015
fourth ventricle developmentGO:002159280.015
cellular amide metabolic processGO:004360340.015
maintenance of locationGO:005123540.015
central nervous system neuron differentiationGO:0021953740.015
mesoderm developmentGO:0007498880.015
carboxylic acid metabolic processGO:0019752220.015
wnt signaling pathway planar cell polarity pathwayGO:006007140.015
urogenital system developmentGO:0001655970.015
heart developmentGO:00075073130.015
entrainment of circadian clockGO:000964920.015
renal tubule developmentGO:006132650.014
cytoskeleton organizationGO:0007010960.014
regulation of organ morphogenesisGO:2000027350.014
axis elongationGO:0003401310.014
specification of axis polarityGO:006500140.014
morphogenesis of a branching structureGO:0001763210.014
neural crest formationGO:0014029140.014
axonogenesisGO:00074091520.014
single organism transportGO:00447652060.014
regulation of mrna catabolic processGO:006101330.014
regulation of synapse organizationGO:005080730.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
production of molecular mediator of immune responseGO:000244020.014
hepatic duct developmentGO:006101120.014
regulation of macromolecule biosynthetic processGO:00105562250.014
neural plate pattern specificationGO:0060896120.014
mononuclear cell proliferationGO:003294310.014
epithelial to mesenchymal transitionGO:0001837210.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
positive regulation of reproductive processGO:200024320.013
positive regulation of cell cycleGO:004578730.013
protein import into nucleusGO:000660630.013
heparan sulfate proteoglycan biosynthetic processGO:001501250.013
generation of neuronsGO:00486993850.013
regulation of cell cycleGO:0051726520.013
negative regulation of protein phosphorylationGO:000193340.013
cellular localizationGO:0051641970.013
cell proliferation in hindbrainGO:002153440.013
sex determinationGO:000753010.013
response to organic substanceGO:00100331530.013
regulation of bindingGO:005109830.013
erythrocyte differentiationGO:0030218540.013
synaptic transmissionGO:0007268350.013
metal ion transportGO:0030001580.013
phosphorus metabolic processGO:00067931090.013
positive regulation of secretionGO:005104710.013
embryonic camera type eye morphogenesisGO:0048596190.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
positive regulation of stress activated mapk cascadeGO:003287430.013
b cell activationGO:004211320.013
negative regulation of multi organism processGO:004390130.013
regulation of cytoplasmic transportGO:190364940.013
regulation of cytokine productionGO:000181730.013
angioblast cell migration involved in selective angioblast sproutingGO:003547540.013
regulation of cellular component movementGO:0051270550.013
single organism metabolic processGO:00447102170.012
mesoderm morphogenesisGO:0048332510.012
negative regulation of immune responseGO:005077720.012
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.012
embryonic epithelial tube formationGO:0001838170.012
establishment of localizationGO:00512342440.012
positive regulation of neurogenesisGO:0050769240.012
cellular ion homeostasisGO:0006873170.012
negative regulation of mitosisGO:004583930.012
negative regulation of multicellular organismal processGO:0051241690.012
determination of dorsal ventral asymmetryGO:0048262340.012
neural precursor cell proliferationGO:0061351200.012
negative regulation of cytoplasmic transportGO:190365020.012
negative regulation of transcription dna templatedGO:0045892450.012
myofibril assemblyGO:0030239480.012
positive regulation of cell differentiationGO:0045597300.012
positive regulation of signal transductionGO:0009967560.012
wnt signaling pathway involved in dorsal ventral axis specificationGO:004433250.012
release of sequestered calcium ion into cytosolGO:005120930.012
mesenchymal cell proliferationGO:001046310.012
regulation of non canonical wnt signaling pathwayGO:200005070.012
primitive hemopoiesisGO:0060215270.012
hypothalamus cell differentiationGO:002197940.012
somatic muscle developmentGO:000752540.012
neuromast depositionGO:004888590.012
cellular response to external stimulusGO:007149620.012
negative regulation of developmental processGO:0051093650.012
peptidyl serine modificationGO:001820920.012
sprouting angiogenesisGO:0002040530.012
collateral sprouting in absence of injuryGO:004866940.012
retina morphogenesis in camera type eyeGO:0060042790.012
negative regulation of defense responseGO:003134820.011
positive regulation of map kinase activityGO:004340630.011
lymphocyte proliferationGO:004665110.011
cellular response to extracellular stimulusGO:003166820.011
regulation of proteolysisGO:0030162240.011
positive regulation of immune effector processGO:000269930.011
regulation of response to biotic stimulusGO:000283120.011
cellular response to transforming growth factor beta stimulusGO:007156070.011
regulation of epithelial cell proliferationGO:005067830.011
regulation of establishment of planar polarityGO:009017540.011
regulation of mrna processingGO:005068430.011
regulation of cellular protein metabolic processGO:0032268520.011
protein sumoylationGO:001692520.011
mitotic cell cycleGO:0000278640.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
ossificationGO:0001503230.011
positive regulation of rna metabolic processGO:0051254590.011
negative regulation of protein import into nucleusGO:004230820.011
proteasomal protein catabolic processGO:001049820.011
medulla oblongata developmentGO:002155040.011
regulation of axonogenesisGO:0050770320.011
cell matrix adhesionGO:000716040.011
regulation of locomotionGO:0040012550.011
regulation of glycoprotein biosynthetic processGO:001055930.011
positive regulation of mesenchymal cell proliferationGO:000205310.011
i kappab kinase nf kappab signalingGO:000724940.011
regulation of cell projection organizationGO:0031344440.011
positive regulation of gliogenesisGO:001401520.011
negative regulation of rna metabolic processGO:0051253480.011
regulation of tube sizeGO:003515020.011
establishment of organelle localizationGO:0051656450.010
embryonic neurocranium morphogenesisGO:0048702150.010
regulation of glial cell differentiationGO:004568540.010
single organism localizationGO:19025782250.010
positive regulation of cell divisionGO:005178120.010
regulation of cell morphogenesis involved in differentiationGO:0010769380.010
calcium ion homeostasisGO:0055074190.010
positive regulation of stem cell proliferationGO:200064810.010
carbohydrate homeostasisGO:003350010.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
single organism biosynthetic processGO:0044711710.010
mesodermal cell differentiationGO:0048333210.010
modification dependent protein catabolic processGO:001994130.010
cell cycleGO:0007049930.010
forebrain generation of neuronsGO:0021872140.010
cellular protein catabolic processGO:004425740.010
regulation of erk1 and erk2 cascadeGO:007037240.010

lzts2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.013