Danio rerio

110 known processes

adra2db

adrenergic, alpha-2D-, receptor b

(Aliases: zgc:194662)

adra2db biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
adrenergic receptor signaling pathwayGO:007187550.992
negative regulation of cyclic nucleotide metabolic processGO:003080070.807
negative regulation of lyase activityGO:005135060.786
negative regulation of innate immune responseGO:004582420.713
Worm
negative regulation of camp metabolic processGO:003081570.678
negative regulation of camp biosynthetic processGO:003081870.648
negative regulation of purine nucleotide biosynthetic processGO:190037270.628
cyclic nucleotide metabolic processGO:0009187180.624
regulation of adenylate cyclase activityGO:004576160.620
aromatic compound biosynthetic processGO:00194382170.602
organophosphate biosynthetic processGO:0090407230.585
camp biosynthetic processGO:0006171110.533
negative regulation of purine nucleotide metabolic processGO:190054370.518
regulation of nitrogen compound metabolic processGO:00511712510.514
negative regulation of nucleotide biosynthetic processGO:003080970.492
regulation of cyclic nucleotide biosynthetic processGO:0030802150.490
nucleobase containing compound biosynthetic processGO:00346542050.489
response to stressGO:00069502630.471
Worm
negative regulation of cyclase activityGO:003128060.469
purine nucleotide biosynthetic processGO:0006164200.451
negative regulation of nucleotide metabolic processGO:004598070.413
regulation of camp biosynthetic processGO:003081790.411
cyclic purine nucleotide metabolic processGO:0052652180.403
negative regulation of cyclic nucleotide biosynthetic processGO:003080370.392
embryonic organ morphogenesisGO:00485622740.387
heterocycle biosynthetic processGO:00181302150.385
organic substance biosynthetic processGO:19015762890.347
camp metabolic processGO:0046058110.341
negative regulation of biological processGO:00485193040.338
organic cyclic compound biosynthetic processGO:19013622230.334
digestive system developmentGO:00551232890.327
cellular macromolecule metabolic processGO:00442603910.302
ribonucleotide biosynthetic processGO:0009260200.291
cellular nitrogen compound biosynthetic processGO:00442712180.285
regulation of primary metabolic processGO:00800903110.251
signal transductionGO:00071654550.209
cellular biosynthetic processGO:00442492860.205
nucleotide biosynthetic processGO:0009165210.205
regulation of macromolecule metabolic processGO:00602553170.204
g protein coupled receptor signaling pathwayGO:0007186740.204
regulation of cellular metabolic processGO:00313233200.176
generation of neuronsGO:00486993850.174
cyclic nucleotide biosynthetic processGO:0009190180.172
biosynthetic processGO:00090582940.171
nitrogen compound metabolic processGO:00068073190.166
regulation of biosynthetic processGO:00098892500.164
single organism localizationGO:19025782250.147
nucleoside phosphate biosynthetic processGO:1901293210.146
heterocycle metabolic processGO:00464832900.142
negative regulation of catalytic activityGO:0043086210.142
negative regulation of biosynthetic processGO:0009890550.140
regulation of response to stimulusGO:00485832690.139
Worm
cellular nitrogen compound metabolic processGO:00346412900.137
immune system processGO:00023762410.136
Worm
nucleobase containing compound metabolic processGO:00061392740.134
regulation of metabolic processGO:00192223590.133
negative regulation of cellular processGO:00485232830.130
regulation of purine nucleotide biosynthetic processGO:1900371150.130
regulation of cyclase activityGO:0031279120.129
cell surface receptor signaling pathwayGO:00071663250.129
ribose phosphate biosynthetic processGO:0046390200.127
blood circulationGO:0008015870.126
Zebrafish
negative regulation of metabolic processGO:0009892860.123
positive regulation of transportGO:005105020.121
muscle cell developmentGO:00550011150.120
gene expressionGO:00104672520.119
circadian sleep wake cycle processGO:002241020.118
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.114
response to abiotic stimulusGO:00096281220.114
regulation of cellular biosynthetic processGO:00313262450.108
regionalizationGO:00030022740.101
organic cyclic compound metabolic processGO:19013603010.101
negative regulation of gene expressionGO:0010629650.098
sleepGO:003043110.094
negative regulation of nitrogen compound metabolic processGO:0051172590.092
regulation of transcription dna templatedGO:00063552130.091
organonitrogen compound metabolic processGO:1901564740.087
carbohydrate derivative biosynthetic processGO:1901137430.087
regulation of developmental processGO:00507932470.085
regulation of nucleobase containing compound metabolic processGO:00192192500.085
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:000718850.082
establishment of localizationGO:00512342440.081
purine containing compound biosynthetic processGO:0072522200.081
regulation of systemic arterial blood pressureGO:000307310.078
regulation of circadian sleep wake cycleGO:004274910.077
regulation of multicellular organismal developmentGO:20000262230.075
chemical homeostasisGO:0048878490.075
single organism transportGO:00447652060.074
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.074
sensory organ morphogenesisGO:00905962000.073
regulation of protein catabolic processGO:004217610.068
defense responseGO:0006952470.068
Worm
regulation of camp metabolic processGO:003081490.067
regulation of rna biosynthetic processGO:20011412130.066
pigmentationGO:0043473850.066
phosphate containing compound metabolic processGO:00067961080.065
transcription dna templatedGO:00063511810.063
organelle organizationGO:00069962270.063
signal transduction in absence of ligandGO:003803410.063
blood vessel developmentGO:00015682460.062
appendage morphogenesisGO:0035107560.061
muscle structure developmentGO:00610611960.061
cellular aromatic compound metabolic processGO:00067252950.060
rna biosynthetic processGO:00327741810.060
response to chemicalGO:00422213200.059
Worm
regulation of rna metabolic processGO:00512522240.059
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.058
single organism metabolic processGO:00447102170.058
regulation of blood pressureGO:000821710.057
heart developmentGO:00075073130.056
cellular protein catabolic processGO:004425740.056
negative regulation of molecular functionGO:0044092230.056
negative regulation of defense responseGO:003134820.055
Worm
multicellular organism growthGO:003526440.054
regulation of signal transductionGO:00099662250.053
Worm
regulation of multicellular organismal processGO:00512392770.053
Zebrafish
regulation of tube sizeGO:003515020.053
striated muscle cell developmentGO:00550021080.052
negative regulation of cellular metabolic processGO:0031324770.052
negative regulation of response to stimulusGO:00485851040.051
Worm
embryonic organ developmentGO:00485683810.051
neuron differentiationGO:00301823530.051
embryonic skeletal system morphogenesisGO:0048704930.051
regulation of nucleic acid templated transcriptionGO:19035062130.050
cellular ketone metabolic processGO:0042180110.050
embryo development ending in birth or egg hatchingGO:00097922710.050
regulation of multicellular organism growthGO:004001440.050
negative regulation of cellular biosynthetic processGO:0031327550.049
embryonic skeletal system developmentGO:0048706970.048
regulation of macromolecule biosynthetic processGO:00105562250.048
eye developmentGO:00016542770.047
regulation of hormone secretionGO:004688320.047
circadian sleep wake cycle sleepGO:005080210.047
regulation of signalingGO:00230512350.047
Worm
single organism biosynthetic processGO:0044711710.047
nucleic acid metabolic processGO:00903042440.047
transmembrane transportGO:00550851200.046
purine containing compound metabolic processGO:0072521290.046
multicellular organismal water homeostasisGO:005089110.045
cellular macromolecule biosynthetic processGO:00346452240.044
cell projection organizationGO:00300302840.044
regulation of biological qualityGO:00650082630.043
Zebrafish
modification dependent macromolecule catabolic processGO:004363230.042
regulation of circadian rhythmGO:004275240.042
phosphorus metabolic processGO:00067931090.042
vasculature developmentGO:00019442780.042
head developmentGO:00603223030.042
sensory organ developmentGO:00074233930.042
positive regulation of rna metabolic processGO:0051254590.042
negative regulation of nucleic acid templated transcriptionGO:1903507450.041
retina development in camera type eyeGO:00600411460.040
immune system developmentGO:00025201910.040
negative regulation of transcription dna templatedGO:0045892450.040
oxoacid metabolic processGO:0043436310.040
chordate embryonic developmentGO:00430092710.040
negative regulation of macromolecule metabolic processGO:0010605760.039
circulatory system processGO:0003013870.039
Zebrafish
positive regulation of nucleobase containing compound metabolic processGO:0045935690.039
response to biotic stimulusGO:0009607970.038
cellular response to unfolded proteinGO:003462020.038
Worm
positive regulation of cellular processGO:00485222010.037
agingGO:000756820.037
negative regulation of nucleobase containing compound metabolic processGO:0045934590.037
regulation of gene expressionGO:00104682650.037
ion transportGO:00068111140.036
inorganic cation transmembrane transportGO:0098662500.036
medial fin morphogenesisGO:0035141140.036
female gonad developmentGO:000858540.036
response to xenobiotic stimulusGO:0009410450.035
cellular component assembly involved in morphogenesisGO:00109271070.035
nucleic acid templated transcriptionGO:00976591810.035
positive regulation of nitrogen compound metabolic processGO:0051173690.035
morphogenesis of an epitheliumGO:00020093330.035
muscle cell differentiationGO:00426921390.034
small molecule metabolic processGO:0044281770.034
negative regulation of phosphate metabolic processGO:0045936130.034
regulation of lyase activityGO:0051339120.034
embryonic heart tube developmentGO:00350501330.034
locomotionGO:00400113130.033
homeostatic processGO:00425921420.033
single organism organelle organizationGO:19025891990.033
regulation of protein complex assemblyGO:004325430.032
transcription from rna polymerase ii promoterGO:0006366800.032
hormone secretionGO:004687920.032
ribose phosphate metabolic processGO:0019693270.031
regulation of cell communicationGO:00106462320.031
Worm
regulation of programmed cell deathGO:00430671010.030
rna metabolic processGO:00160702190.030
transportGO:00068102200.030
regulation of transcription from rna polymerase ii promoterGO:00063571140.030
amine metabolic processGO:000930820.030
growthGO:00400071740.029
glucose homeostasisGO:004259310.029
ear developmentGO:00435831270.029
circadian sleep wake cycleGO:004274520.029
response to radiationGO:0009314510.029
appendage developmentGO:0048736800.029
negative regulation of macromolecule biosynthetic processGO:0010558480.029
leukocyte proliferationGO:007066110.029
gastrulationGO:00073692080.028
digestive tract morphogenesisGO:00485462310.028
proteolysis involved in cellular protein catabolic processGO:005160330.028
stem cell differentiationGO:00488631170.028
system processGO:00030081850.027
Zebrafish
embryonic skeletal joint developmentGO:007249830.027
purine nucleotide metabolic processGO:0006163270.027
camera type eye developmentGO:00430102220.027
stem cell fate commitmentGO:004886510.027
cytokinesisGO:000091030.027
fin developmentGO:0033333770.026
positive regulation of biological processGO:00485182530.026
cellular carbohydrate metabolic processGO:004426240.026
ion transmembrane transportGO:0034220910.026
negative regulation of signalingGO:0023057960.026
cellular component movementGO:00069283350.026
organelle assemblyGO:00709251100.026
purine ribonucleotide biosynthetic processGO:0009152200.025
positive regulation of cellular catabolic processGO:003133130.025
peptide transportGO:001583310.025
positive regulation of nucleic acid templated transcriptionGO:1903508570.025
negative regulation of adenylate cyclase activityGO:000719460.025
organic acid metabolic processGO:0006082310.025
wound healingGO:0042060900.025
lymphocyte proliferationGO:004665110.025
regulation of anatomical structure morphogenesisGO:00226031300.025
hindbrain developmentGO:0030902910.025
regulation of establishment of protein localizationGO:007020140.024
regulation of cellular amine metabolic processGO:003323800.024
tube morphogenesisGO:00352393490.024
positive regulation of macromolecule metabolic processGO:0010604930.024
regulation of transporter activityGO:003240920.024
response to woundingGO:00096111160.024
epiboly involved in gastrulation with mouth forming secondGO:0055113350.024
maintenance of locationGO:005123540.024
deathGO:00162651210.024
regulation of cellular ketone metabolic processGO:001056570.024
striated muscle cell differentiationGO:00511461290.023
regulation of protein import into nucleusGO:004230620.023
positive regulation of secretionGO:005104710.023
negative regulation of protein transportGO:005122430.023
regulation of heart rateGO:000202750.023
Zebrafish
negative regulation of catabolic processGO:000989530.023
camera type eye morphogenesisGO:00485931080.023
neuron developmentGO:00486662620.023
startle responseGO:000196440.023
pancreas developmentGO:0031016840.023
apoptotic processGO:00069151160.022
negative regulation of cell differentiationGO:0045596460.022
segmentationGO:0035282970.022
regulation of apoptotic processGO:0042981980.022
regulation of blood vessel sizeGO:005088020.022
response to topologically incorrect proteinGO:003596620.022
Worm
hemopoiesisGO:00300971830.022
negative regulation of phosphorus metabolic processGO:0010563130.022
forebrain cell migrationGO:002188510.021
regulation of molecular functionGO:0065009700.021
eye morphogenesisGO:00485921440.021
regulation of circadian sleep wake cycle sleepGO:004518710.021
er nucleus signaling pathwayGO:000698420.021
Worm
myofibril assemblyGO:0030239480.021
positive regulation of cellular metabolic processGO:0031325940.021
carbohydrate derivative metabolic processGO:1901135610.021
protein localization to nucleusGO:003450430.020
vasculogenesisGO:0001570410.020
heart contractionGO:0060047710.020
Zebrafish
positive regulation of catabolic processGO:000989640.020
carboxylic acid metabolic processGO:0019752220.020
sensory perceptionGO:0007600390.020
regulation of response to stressGO:0080134360.020
Worm
angiogenesisGO:00015251580.019
negative regulation of immune responseGO:005077720.019
Worm
cell motilityGO:00488702440.019
proteasomal protein catabolic processGO:001049820.019
stem cell divisionGO:001714510.019
regulation of phosphate metabolic processGO:0019220430.019
cellular amine metabolic processGO:004410620.019
mesenchyme developmentGO:00604851270.019
protein metabolic processGO:00195381830.019
digestive tract developmentGO:00485652650.018
inorganic ion transmembrane transportGO:0098660570.018
positive regulation of metabolic processGO:00098931080.018
carbohydrate homeostasisGO:003350010.018
cell part morphogenesisGO:00329902460.018
intracellular estrogen receptor signaling pathwayGO:003052030.018
response to nutrientGO:000758430.018
larval developmentGO:000216420.018
response to other organismGO:0051707970.017
ribonucleotide metabolic processGO:0009259270.017
developmental growthGO:00485891660.017
mononuclear cell proliferationGO:003294310.017
somite developmentGO:0061053960.017
positive regulation of cellular biosynthetic processGO:0031328680.017
regulation of growthGO:0040008420.017
response to vitaminGO:003327330.017
nucleotide metabolic processGO:0009117280.017
regulation of cell differentiationGO:00455951420.017
intracellular signal transductionGO:0035556850.016
localization of cellGO:00516742440.016
positive regulation of cellular amine metabolic processGO:003324000.016
negative regulation of muscle tissue developmentGO:190186220.016
water homeostasisGO:003010440.016
regulation of cytoplasmic transportGO:190364940.016
regulation of inflammatory responseGO:005072720.016
negative regulation of rna biosynthetic processGO:1902679450.016
positive regulation of cellular component biogenesisGO:004408930.016
neural crest cell differentiationGO:0014033720.016
cation homeostasisGO:0055080330.016
response to monosaccharideGO:003428430.016
positive regulation of protein complex assemblyGO:003133420.016
phototransductionGO:000760220.016
cellular component biogenesisGO:00440851780.016
regulation of protein polymerizationGO:003227120.015
negative regulation of protein phosphorylationGO:000193340.015
ubiquitin dependent protein catabolic processGO:000651130.015
gland developmentGO:00487321430.015
sodium ion transportGO:0006814240.015
somitogenesisGO:0001756870.015
embryonic hemopoiesisGO:0035162530.015
muscle organ developmentGO:00075171010.015
cell deathGO:00082191210.015
regulation of response to nutrient levelsGO:003210710.014
muscle tissue developmentGO:00605371100.014
single organism nuclear importGO:190259330.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
regulation of blood circulationGO:1903522320.014
Zebrafish
response to salt stressGO:0009651100.014
abducens nerve developmentGO:002156010.014
response to external stimulusGO:00096052640.014
cellular response to radiationGO:007147840.014
modification dependent protein catabolic processGO:001994130.014
phagocytosisGO:000690930.013
protein importGO:001703830.013
myotube cell developmentGO:0014904350.013
macromolecule modificationGO:00434121110.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
cellular response to chemical stimulusGO:00708871570.013
Worm
gastrulation with mouth forming secondGO:0001702440.013
axon developmentGO:00615641660.013
embryonic skeletal joint morphogenesisGO:006027230.013
protein modification processGO:00362111000.013
cellular component morphogenesisGO:00329893360.013
cardiac cell developmentGO:0055006210.013
regulation of cell motilityGO:2000145460.013
negative regulation of multicellular organismal processGO:0051241690.013
regulation of catalytic activityGO:0050790550.013
positive regulation of cell cycleGO:004578730.012
regulation of cell activationGO:005086510.012
response to light stimulusGO:0009416460.012
cell migrationGO:00164772370.012
positive regulation of transcription dna templatedGO:0045893570.012
cellular amino acid metabolic processGO:000652070.012
response to glucoseGO:000974930.012
positive regulation of cell differentiationGO:0045597300.012
negative regulation of kinase activityGO:003367340.012
establishment of protein localization to organelleGO:007259440.012
cardiac muscle cell developmentGO:0055013200.012
regulation of cell deathGO:00109411030.012
lipid storageGO:001991510.012
regulation of cellular amino acid metabolic processGO:000652100.012
regenerationGO:0031099910.012
cellular component assemblyGO:00226071700.012
positive regulation of biosynthetic processGO:0009891680.012
response to oxygen levelsGO:0070482250.012
immune responseGO:0006955280.012
Worm
neuron projection developmentGO:00311751800.012
cardiac cell fate commitmentGO:006091110.012
determination of bilateral symmetryGO:00098552040.012
trigeminal motor nucleus developmentGO:002173120.012
cellular response to nutrient levelsGO:003166920.012
positive regulation of gene expressionGO:0010628710.012
regulation of growth rateGO:004000910.012
negative regulation of rna metabolic processGO:0051253480.011
skeletal muscle organ developmentGO:0060538780.011
cell proliferationGO:0008283800.011
regulation of transmembrane transporter activityGO:002289820.011
regulation of nucleotide biosynthetic processGO:0030808150.011
morphogenesis of an epithelial sheetGO:0002011490.011
epithelial cell differentiationGO:00308551160.011
cellular response to light stimulusGO:007148240.011
regulation of cellular protein metabolic processGO:0032268520.011
proteolysisGO:0006508380.011
cell projection morphogenesisGO:00488582440.011
female sex differentiationGO:004666040.011
regulation of nucleocytoplasmic transportGO:004682220.011
negative regulation of feeding behaviorGO:200025220.010
regulation of water loss via skinGO:003356110.010
negative regulation of secretionGO:005104820.010
regulation of cellular protein catabolic processGO:190336210.010
retinal ganglion cell axon guidanceGO:0031290350.010
organophosphate metabolic processGO:0019637370.010
regulation of skeletal muscle tissue developmentGO:004864140.010

adra2db disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.017
sensory system diseaseDOID:005015500.017
eye and adnexa diseaseDOID:149200.017
pfeiffer syndromeDOID:1470500.013
musculoskeletal system diseaseDOID:1700.013
synostosisDOID:1197100.013
connective tissue diseaseDOID:6500.013
dysostosisDOID:193400.013
acrocephalosyndactyliaDOID:1296000.013
bone diseaseDOID:008000100.013
bone development diseaseDOID:008000600.013
physical disorderDOID:008001500.010
orofacial cleftDOID:005056700.010