Danio rerio

0 known processes

sgpp1

sphingosine-1-phosphate phosphatase 1

sgpp1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell surface receptor signaling pathwayGO:00071663250.180
multicellular organism growthGO:003526440.162
regulation of multicellular organism growthGO:004001440.141
regulation of signal transductionGO:00099662250.138
maintenance of locationGO:005123540.136
blood vessel morphogenesisGO:00485142160.129
cellular hormone metabolic processGO:0034754190.126
signal transductionGO:00071654550.113
estrogen metabolic processGO:000821020.103
enzyme linked receptor protein signaling pathwayGO:00071671060.098
ovulation cycleGO:004269820.091
female gonad developmentGO:000858540.089
cell migrationGO:00164772370.088
skeletal system developmentGO:00015011810.087
ameboidal type cell migrationGO:00016671430.083
organic acid metabolic processGO:0006082310.080
lipid homeostasisGO:005508830.076
localization of cellGO:00516742440.076
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.073
regulation of multicellular organismal processGO:00512392770.073
regulation of inflammatory responseGO:005072720.073
acylglycerol homeostasisGO:005509020.071
locomotionGO:00400113130.070
cellular response to external stimulusGO:007149620.069
larval developmentGO:000216420.068
female sex differentiationGO:004666040.066
defense responseGO:0006952470.064
blood vessel developmentGO:00015682460.064
regulation of protein transportGO:005122330.063
protein secretionGO:000930610.060
cell motilityGO:00488702440.059
transmembrane transportGO:00550851200.058
tube morphogenesisGO:00352393490.058
fatty acid biosynthetic processGO:000663340.058
regulation of biological qualityGO:00650082630.056
single organism biosynthetic processGO:0044711710.056
cellular component movementGO:00069283350.054
rna biosynthetic processGO:00327741810.054
small molecule metabolic processGO:0044281770.054
positive regulation of transportGO:005105020.054
agingGO:000756820.054
response to steroid hormoneGO:0048545350.053
development of primary female sexual characteristicsGO:004654540.053
vasculogenesisGO:0001570410.052
cell migration involved in gastrulationGO:0042074790.052
aromatic compound biosynthetic processGO:00194382170.051
adult behaviorGO:003053420.051
regulation of primary metabolic processGO:00800903110.050
digestive tract morphogenesisGO:00485462310.050
heart developmentGO:00075073130.050
regulation of lipase activityGO:006019120.049
innate immune responseGO:0045087130.049
response to ketoneGO:190165410.049
regulation of response to stimulusGO:00485832690.049
cellular nitrogen compound metabolic processGO:00346412900.049
organic substance biosynthetic processGO:19015762890.048
gtp metabolic processGO:004603940.048
immune system processGO:00023762410.047
response to stressGO:00069502630.047
carboxylic acid metabolic processGO:0019752220.046
response to bacteriumGO:0009617580.046
toll like receptor signaling pathwayGO:000222440.046
regulation of developmental processGO:00507932470.045
hormone metabolic processGO:0042445190.045
skeletal system morphogenesisGO:00487051020.044
biosynthetic processGO:00090582940.043
lipid metabolic processGO:0006629520.043
embryonic organ morphogenesisGO:00485622740.043
response to alkaloidGO:004327920.043
protein targeting to nucleusGO:004474430.042
positive regulation of catabolic processGO:000989640.042
positive regulation of gtpase activityGO:004354710.042
nitrogen compound metabolic processGO:00068073190.041
sodium ion transmembrane transportGO:0035725210.040
regulation of biosynthetic processGO:00098892500.040
urogenital system developmentGO:0001655970.040
gastrulationGO:00073692080.039
transcription dna templatedGO:00063511810.039
regulation of hydrolase activityGO:0051336280.039
guanosine containing compound catabolic processGO:190106920.038
response to woundingGO:00096111160.038
cellular biosynthetic processGO:00442492860.038
positive regulation of gtp catabolic processGO:003312610.038
transcription from rna polymerase ii promoterGO:0006366800.038
gtp catabolic processGO:000618420.038
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.037
developmental growthGO:00485891660.037
lipid storageGO:001991510.036
apoptotic processGO:00069151160.036
oxoacid metabolic processGO:0043436310.036
regulation of nucleotide catabolic processGO:003081120.036
regulation of transcription dna templatedGO:00063552130.035
cellular response to extracellular stimulusGO:003166820.035
vasculature developmentGO:00019442780.035
nucleocytoplasmic transportGO:000691340.034
cellular amine metabolic processGO:004410620.034
positive regulation of nucleoside metabolic processGO:004597910.034
homeostatic processGO:00425921420.034
regulation of gene expressionGO:00104682650.033
regulation of nitrogen compound metabolic processGO:00511712510.033
cation transmembrane transportGO:0098655650.033
digestive system developmentGO:00551232890.033
cognitionGO:005089010.033
chordate embryonic developmentGO:00430092710.032
macromolecule biosynthetic processGO:00090592270.032
negative regulation of secretionGO:005104820.032
regulation of nucleobase containing compound metabolic processGO:00192192500.032
guanosine containing compound metabolic processGO:190106840.031
ion transmembrane transportGO:0034220910.031
single organism nuclear importGO:190259330.031
positive regulation of purine nucleotide catabolic processGO:003312310.031
amine metabolic processGO:000930820.031
regulation of hormone levelsGO:0010817210.031
embryonic organ developmentGO:00485683810.030
positive regulation of nucleotide catabolic processGO:003081310.030
regulation of cellular amine metabolic processGO:003323800.030
myeloid leukocyte migrationGO:0097529120.030
single organism metabolic processGO:00447102170.030
cellular ketone metabolic processGO:0042180110.030
establishment of localizationGO:00512342440.030
dicarboxylic acid transportGO:000683510.030
positive regulation of innate immune responseGO:004508980.030
regulation of cellular ketone metabolic processGO:001056570.030
renal system developmentGO:0072001940.029
regulation of endocytosisGO:003010070.029
negative regulation of secretion by cellGO:190353120.029
androgen metabolic processGO:000820920.029
regulation of establishment of protein localizationGO:007020140.029
regulation of macromolecule metabolic processGO:00602553170.029
tyrosine phosphorylation of stat proteinGO:000726010.029
regulation of gtp catabolic processGO:003312420.029
establishment of protein localization to organelleGO:007259440.029
regulation of sequestering of calcium ionGO:005128240.029
positive regulation of cellular amine metabolic processGO:003324000.029
regulation of signalingGO:00230512350.028
positive regulation of cytosolic calcium ion concentrationGO:000720440.028
regulation of programmed cell deathGO:00430671010.028
regulation of purine nucleotide catabolic processGO:003312120.028
negative regulation of defense responseGO:003134820.028
mitochondrion organizationGO:000700540.027
regulation of sterol transportGO:003237130.027
cellular response to biotic stimulusGO:007121630.027
muscle structure developmentGO:00610611960.027
system processGO:00030081850.026
kidney developmentGO:0001822920.026
cation transportGO:0006812810.026
nucleic acid metabolic processGO:00903042440.026
long chain fatty acid metabolic processGO:000167610.026
cellular response to nutrient levelsGO:003166920.026
positive regulation of lipase activityGO:006019310.026
protein metabolic processGO:00195381830.026
appendage developmentGO:0048736800.026
negative regulation of biological processGO:00485193040.025
positive regulation of cell cycleGO:004578730.025
cellular response to molecule of bacterial originGO:007121930.025
positive regulation of cellular catabolic processGO:003133130.025
regulation of nucleoside metabolic processGO:000911820.025
response to chemicalGO:00422213200.024
positive regulation of i kappab kinase nf kappab signalingGO:004312330.024
inorganic ion transmembrane transportGO:0098660570.024
regulation of tube sizeGO:003515020.024
response to organic substanceGO:00100331530.024
protein localization to nucleusGO:003450430.024
organism emergence from protective structureGO:007168440.024
regulation of cellular macromolecule biosynthetic processGO:20001122220.024
positive regulation of catalytic activityGO:0043085250.023
nucleobase containing compound metabolic processGO:00061392740.023
regulation of cellular metabolic processGO:00313233200.023
regulation of gtpase activityGO:004308720.023
regulation of rna metabolic processGO:00512522240.023
programmed cell deathGO:00125011190.023
sensory perception of chemical stimulusGO:000760630.022
regulation of cell activationGO:005086510.022
transportGO:00068102200.022
sequestering of metal ionGO:005123830.022
sensory organ developmentGO:00074233930.022
determination of bilateral symmetryGO:00098552040.022
epithelial tube morphogenesisGO:00605621480.022
hatchingGO:003518840.022
regulation of cytokine productionGO:000181730.021
organic cyclic compound metabolic processGO:19013603010.021
calcium ion transport into cytosolGO:006040230.021
embryonic heart tube developmentGO:00350501330.021
regulation of behaviorGO:0050795240.021
protein import into nucleusGO:000660630.021
cellular response to organic substanceGO:00713101050.021
neuron differentiationGO:00301823530.021
muscle cell developmentGO:00550011150.021
organic cyclic compound biosynthetic processGO:19013622230.021
regulation of bindingGO:005109830.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
steroid metabolic processGO:000820270.020
cytosolic calcium ion transportGO:006040130.020
regulation of phGO:000688530.020
neurotransmitter transportGO:000683620.020
carbon dioxide transportGO:001567030.020
regulation of cellular amino acid metabolic processGO:000652100.020
cellular response to starvationGO:000926710.020
gene expressionGO:00104672520.020
rna metabolic processGO:00160702190.020
g protein coupled receptor signaling pathwayGO:0007186740.020
proteolysisGO:0006508380.020
growthGO:00400071740.020
i kappab kinase nf kappab signalingGO:000724940.020
positive regulation of secretion by cellGO:190353210.020
regulation of cell communicationGO:00106462320.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
response to metal ionGO:0010038340.019
epithelial cell differentiationGO:00308551160.019
regulation of jak stat cascadeGO:004642530.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
hematopoietic or lymphoid organ developmentGO:00485341910.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
nucleobase containing compound biosynthetic processGO:00346542050.019
hemopoiesisGO:00300971830.019
neuron developmentGO:00486662620.019
nucleic acid templated transcriptionGO:00976591810.019
heterocycle biosynthetic processGO:00181302150.019
alcohol biosynthetic processGO:004616520.019
regulation of protein ubiquitinationGO:003139630.019
compound eye developmentGO:004874920.019
regulation of cellular biosynthetic processGO:00313262450.018
organelle fusionGO:004828430.018
nuclear transportGO:005116940.018
cellular amino acid metabolic processGO:000652070.018
phagocytosisGO:000690930.018
triglyceride homeostasisGO:007032820.018
apoptotic signaling pathwayGO:0097190230.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
cellular localizationGO:0051641970.018
regulation of molecular functionGO:0065009700.018
smooth muscle contractionGO:000693920.018
response to hexoseGO:000974630.018
autophagyGO:000691440.018
cytokinesisGO:000091030.018
negative regulation of programmed cell deathGO:0043069580.018
sensory perception of smellGO:000760820.018
regulation of tyrosine phosphorylation of stat proteinGO:004250910.018
regulation of synapse organizationGO:005080730.018
chemical homeostasisGO:0048878490.018
cellular response to hormone stimulusGO:0032870390.017
head developmentGO:00603223030.017
organonitrogen compound metabolic processGO:1901564740.017
response to endogenous stimulusGO:0009719830.017
response to carbohydrateGO:000974330.017
regionalizationGO:00030022740.017
brain developmentGO:00074202930.017
monocarboxylic acid biosynthetic processGO:0072330120.017
positive regulation of cellular component biogenesisGO:004408930.017
negative regulation of multicellular organismal processGO:0051241690.017
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.017
wound healingGO:0042060900.017
regulation of ion transmembrane transporter activityGO:003241220.017
positive regulation of nucleobase containing compound metabolic processGO:0045935690.017
organic substance transportGO:0071702580.017
response to monosaccharideGO:003428430.017
regulation of protein targetingGO:190353320.016
cellular response to chemical stimulusGO:00708871570.016
response to vitaminGO:003327330.016
organic acid biosynthetic processGO:0016053120.016
negative regulation of cellular processGO:00485232830.016
response to glucoseGO:000974930.016
regulation of transmembrane transporter activityGO:002289820.016
stem cell proliferationGO:007208940.016
retina development in camera type eyeGO:00600411460.016
meiotic nuclear divisionGO:000712640.016
lateral line developmentGO:0048882660.016
regulation of blood pressureGO:000821710.016
peptide transportGO:001583310.016
peptidyl serine phosphorylationGO:001810510.016
neurotransmitter secretionGO:000726920.016
cellular macromolecule metabolic processGO:00442603910.016
morphogenesis of an epitheliumGO:00020093330.016
centrosome organizationGO:005129710.016
peptide metabolic processGO:000651810.016
negative regulation of protein phosphorylationGO:000193340.016
immune responseGO:0006955280.015
single organism localizationGO:19025782250.015
regulation of protein catabolic processGO:004217610.015
neural crest cell differentiationGO:0014033720.015
cellular protein metabolic processGO:00442671290.015
striated muscle cell developmentGO:00550021080.015
embryonic heart tube morphogenesisGO:00031431080.015
fatty acid transportGO:001590810.015
heterocycle metabolic processGO:00464832900.015
regulation of apoptotic processGO:0042981980.015
stem cell maintenanceGO:001982740.015
dorsal ventral pattern formationGO:00099531250.015
nuclear importGO:005117030.015
regulation of nucleocytoplasmic transportGO:004682220.015
intracellular signal transductionGO:0035556850.015
macroautophagyGO:001623610.015
cell deathGO:00082191210.015
deathGO:00162651210.015
response to glucocorticoidGO:005138410.015
exocytosisGO:000688710.015
gas transportGO:001566930.015
regulation of synaptic plasticityGO:004816710.015
synaptic growth at neuromuscular junctionGO:005112420.014
positive regulation of cell communicationGO:0010647560.014
positive regulation of secretionGO:005104710.014
cellular component disassemblyGO:002241110.014
secondary metabolic processGO:001974830.014
multi organism processGO:00517041340.014
inorganic cation transmembrane transportGO:0098662500.014
regulation of cardiac muscle contractionGO:005511720.014
negative regulation of cell deathGO:0060548600.014
hormone secretionGO:004687920.014
regulation of metal ion transportGO:001095940.014
cellular response to lipopolysaccharideGO:007122230.014
positive regulation of inflammatory responseGO:005072910.014
glycerolipid biosynthetic processGO:004501710.014
inner ear developmentGO:00488391260.014
positive regulation of epithelial cell migrationGO:001063420.014
regulation of transporter activityGO:003240920.014
regulation of blood vessel sizeGO:005088020.014
membrane fusionGO:006102520.014
regulation of cytoplasmic transportGO:190364940.014
chemotaxisGO:00069351040.014
melanin metabolic processGO:000658220.014
positive regulation of biological processGO:00485182530.014
small molecule biosynthetic processGO:0044283160.014
larval behaviorGO:003053750.014
regulation of macromolecule biosynthetic processGO:00105562250.014
regulation of dna replicationGO:000627530.014
b cell activationGO:004211320.014
neuron neuron synaptic transmissionGO:000727010.013
regulation of cell deathGO:00109411030.013
protein importGO:001703830.013
glucose homeostasisGO:004259310.013
regulation of protein bindingGO:004339330.013
regulation of developmental growthGO:0048638380.013
regulation of cellular protein catabolic processGO:190336210.013
embryonic skeletal system developmentGO:0048706970.013
fin developmentGO:0033333770.013
cellular amide metabolic processGO:004360340.013
single organism transportGO:00447652060.013
specification of symmetryGO:00097992040.013
mitotic dna damage checkpointGO:004477340.013
lateral inhibitionGO:004633110.013
digestive tract developmentGO:00485652650.013
dna catabolic processGO:000630810.013
negative regulation of protein transportGO:005122430.013
single organism membrane fusionGO:004480120.013
atp catabolic processGO:000620040.013
g2 m transition of mitotic cell cycleGO:000008640.013
cellular response to lipidGO:0071396390.013
regulation of lipid transportGO:003236840.013
neuromuscular process controlling balanceGO:005088530.013
regulation of protein complex assemblyGO:004325430.013
negative regulation of protein kinase activityGO:000646940.013
multi organism cellular processGO:004476420.013
organic hydroxy compound transportGO:0015850140.013
central nervous system developmentGO:00074173870.013
cellular chemical homeostasisGO:0055082170.013
actin filament based movementGO:003004810.013
regulation of synapse assemblyGO:005196330.013
small gtpase mediated signal transductionGO:000726480.013
regulation of response to nutrient levelsGO:003210710.013
regulation of epithelial cell proliferationGO:005067830.013
intracellular receptor signaling pathwayGO:0030522300.013
inositol lipid mediated signalingGO:004801720.013
endosomal transportGO:001619720.013
positive regulation of defense responseGO:003134990.012
calcium ion importGO:007050940.012
digestive system processGO:002260090.012
golgi vesicle transportGO:004819330.012
cellular macromolecule biosynthetic processGO:00346452240.012
response to external stimulusGO:00096052640.012
negative regulation of epithelial cell proliferationGO:005068010.012
divalent inorganic cation transportGO:0072511210.012
nucleoside monophosphate catabolic processGO:000912540.012
cellular response to organic cyclic compoundGO:0071407380.012
positive regulation of macromolecule metabolic processGO:0010604930.012
regulation of endopeptidase activityGO:0052548230.012
carbohydrate homeostasisGO:003350010.012
phosphorus metabolic processGO:00067931090.012
regulation of response to oxidative stressGO:190288220.012
neuroblast proliferationGO:000740520.012
determination of left right symmetryGO:00073681790.012
determination of heart left right asymmetryGO:00613711170.012
regulation of response to extracellular stimulusGO:003210410.012
positive regulation of lipid metabolic processGO:004583410.012
negative regulation of metabolic processGO:0009892860.012
taxisGO:00423301090.012
positive regulation of cellular metabolic processGO:0031325940.012
regulation of circadian rhythmGO:004275240.012
membrane invaginationGO:001032410.012
regulation of membrane potentialGO:0042391230.012
embryo development ending in birth or egg hatchingGO:00097922710.012
positive regulation of dna metabolic processGO:005105410.012
release of sequestered calcium ion into cytosolGO:005120930.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
stem cell divisionGO:001714510.012
regulation of intracellular protein transportGO:003315730.012
regulation of calcium ion transportGO:005192420.012
immune system developmentGO:00025201910.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
actin mediated cell contractionGO:007025210.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
cellular response to light stimulusGO:007148240.012
mononuclear cell proliferationGO:003294310.011
organelle organizationGO:00069962270.011
angiogenesisGO:00015251580.011
peptidyl serine modificationGO:001820920.011
transmission of nerve impulseGO:0019226190.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
response to estrogenGO:0043627270.011
ear developmentGO:00435831270.011
regulation of protein processingGO:0070613100.011
fluid transportGO:0042044170.011
meiotic cell cycle processGO:190304630.011
bmp signaling pathwayGO:0030509520.011
regulation of protein localization to nucleusGO:190018020.011
monoamine transportGO:001584410.011
response to organic cyclic compoundGO:0014070510.011
regulation of localizationGO:00328791040.011
ion homeostasisGO:0050801410.011
positive regulation of cell adhesionGO:004578510.011
mechanosensory behaviorGO:000763820.011
positive regulation of ras gtpase activityGO:003232010.011
ribonucleoside monophosphate catabolic processGO:000915840.011
regulation of multicellular organismal developmentGO:20000262230.011
regulation of organ growthGO:004662030.011
phagocytosis engulfmentGO:000691110.011
regulation of striated muscle contractionGO:000694220.011
posterior lateral line neuromast developmentGO:0048919200.011
lateral line system developmentGO:0048925760.011
neuromast developmentGO:0048884460.011
positive regulation of blood circulationGO:190352420.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
regulation of neural precursor cell proliferationGO:200017730.011
negative regulation of cytokine productionGO:000181810.011
protein homooligomerizationGO:005126030.011
mechanosensory lateral line system developmentGO:0048881490.011
rna localizationGO:000640340.011
regulation of metabolic processGO:00192223590.011
macromolecular complex disassemblyGO:003298410.011
protein dephosphorylationGO:000647030.011
cell substrate adhesionGO:003158940.010
cellular component assembly involved in morphogenesisGO:00109271070.010
phosphate containing compound metabolic processGO:00067961080.010
carboxylic acid biosynthetic processGO:0046394120.010
regulation of growthGO:0040008420.010
regulation of neurological system processGO:003164420.010
metal ion transportGO:0030001580.010
ion transportGO:00068111140.010
neural crest cell migrationGO:0001755420.010
eye developmentGO:00016542770.010
positive regulation of neuron deathGO:190121610.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
extrinsic apoptotic signaling pathwayGO:009719130.010
regulation of cellular protein metabolic processGO:0032268520.010
stem cell differentiationGO:00488631170.010
protein complex disassemblyGO:004324110.010
regulation of nucleic acid templated transcriptionGO:19035062130.010
inflammatory responseGO:000695480.010
leukocyte proliferationGO:007066110.010
actomyosin structure organizationGO:0031032530.010
purine nucleoside monophosphate catabolic processGO:000912840.010
regulation of neurotransmitter transportGO:005158810.010
spermatid developmentGO:000728620.010
cellular carbohydrate metabolic processGO:004426240.010
negative regulation of tor signalingGO:003200720.010
carbohydrate derivative metabolic processGO:1901135610.010

sgpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.048
sensory system diseaseDOID:005015500.021
eye diseaseDOID:561400.021
eye and adnexa diseaseDOID:149200.021
musculoskeletal system diseaseDOID:1700.018
retinal diseaseDOID:567900.015
retinal degenerationDOID:846600.015
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013