Danio rerio

0 known processes

manba

mannosidase, beta A, lysosomal

(Aliases: zgc:55493,zgc:76896,MGC55493)

manba biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.100
agingGO:000756820.053
cellular protein catabolic processGO:004425740.049
maintenance of locationGO:005123540.044
modification dependent protein catabolic processGO:001994130.041
modification dependent macromolecule catabolic processGO:004363230.040
ubiquitin dependent protein catabolic processGO:000651130.038
positive regulation of transportGO:005105020.038
establishment of protein localization to organelleGO:007259440.038
proteolysis involved in cellular protein catabolic processGO:005160330.036
cellular macromolecule metabolic processGO:00442603910.035
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.034
cellular aromatic compound metabolic processGO:00067252950.034
phagocytosisGO:000690930.033
cellular response to external stimulusGO:007149620.033
membrane fusionGO:006102520.033
multicellular organism growthGO:003526440.032
nitrogen compound metabolic processGO:00068073190.032
positive regulation of cellular catabolic processGO:003133130.032
heterocycle metabolic processGO:00464832900.031
positive regulation of catabolic processGO:000989640.031
meiotic nuclear divisionGO:000712640.031
regulation of multicellular organism growthGO:004001440.030
cellular nitrogen compound metabolic processGO:00346412900.030
protein localization to nucleusGO:003450430.030
mitochondrion organizationGO:000700540.030
biosynthetic processGO:00090582940.030
proteasomal protein catabolic processGO:001049820.030
regulation of protein complex assemblyGO:004325430.029
organic cyclic compound metabolic processGO:19013603010.029
lipid storageGO:001991510.029
signal transductionGO:00071654550.029
regulation of metabolic processGO:00192223590.029
protein importGO:001703830.029
gene expressionGO:00104672520.029
regulation of establishment of protein localizationGO:007020140.028
nucleobase containing compound metabolic processGO:00061392740.027
rna metabolic processGO:00160702190.027
organelle fusionGO:004828430.026
response to drugGO:004249330.026
stem cell maintenanceGO:001982740.026
cellular biosynthetic processGO:00442492860.026
nucleocytoplasmic transportGO:000691340.026
amine metabolic processGO:000930820.026
nuclear transportGO:005116940.026
positive regulation of cell cycleGO:004578730.026
regulation of cellular metabolic processGO:00313233200.026
positive regulation of cellular component biogenesisGO:004408930.026
cellular response to extracellular stimulusGO:003166820.025
protein import into nucleusGO:000660630.025
regulation of mrna processingGO:005068430.025
regulation of cytokine productionGO:000181730.025
regulation of macromolecule metabolic processGO:00602553170.025
gtp metabolic processGO:004603940.025
guanosine containing compound metabolic processGO:190106840.025
cellular amine metabolic processGO:004410620.025
single organism nuclear importGO:190259330.025
regulation of meiotic cell cycleGO:005144510.024
protein localization to plasma membraneGO:007265910.024
nucleic acid metabolic processGO:00903042440.024
nuclear importGO:005117030.024
single organism membrane fusionGO:004480120.024
gtp catabolic processGO:000618420.024
protein polymerizationGO:005125840.024
guanosine containing compound catabolic processGO:190106920.024
response to chemicalGO:00422213200.024
regulation of bindingGO:005109830.024
regulation of primary metabolic processGO:00800903110.023
organic substance biosynthetic processGO:19015762890.023
tube morphogenesisGO:00352393490.023
cellular response to nutrient levelsGO:003166920.023
regulation of protein catabolic processGO:004217610.023
negative regulation of protein phosphorylationGO:000193340.023
protein targeting to nucleusGO:004474430.023
regulation of nitrogen compound metabolic processGO:00511712510.023
endosomal transportGO:001619720.023
cellular response to starvationGO:000926710.022
single organism metabolic processGO:00447102170.022
macromolecule biosynthetic processGO:00090592270.022
response to stressGO:00069502630.022
regulation of protein ubiquitinationGO:003139630.022
regulation of cellular amine metabolic processGO:003323800.022
regulation of protein transportGO:005122330.022
regulation of cytoplasmic transportGO:190364940.022
stem cell proliferationGO:007208940.022
meiotic cell cycle processGO:190304630.021
cellular component disassemblyGO:002241110.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
cognitionGO:005089010.021
central nervous system developmentGO:00074173870.021
regulation of protein localization to nucleusGO:190018020.021
regulation of protein import into nucleusGO:004230620.021
regulation of protein targetingGO:190353320.021
regulation of protein modification by small protein conjugation or removalGO:190332030.021
cellular macromolecule biosynthetic processGO:00346452240.021
autophagyGO:000691440.020
locomotionGO:00400113130.020
regulation of intracellular protein transportGO:003315730.020
regulation of cellular biosynthetic processGO:00313262450.020
rna localizationGO:000640340.020
response to topologically incorrect proteinGO:003596620.020
regulation of response to stimulusGO:00485832690.020
morphogenesis of an epitheliumGO:00020093330.020
regulation of nucleocytoplasmic transportGO:004682220.020
negative regulation of biological processGO:00485193040.019
organic cyclic compound biosynthetic processGO:19013622230.019
golgi vesicle transportGO:004819330.019
cytokinesisGO:000091030.019
cell cycle g1 s phase transitionGO:004484310.019
regulation of gene expressionGO:00104682650.019
regulation of cell communicationGO:00106462320.019
regulation of mrna splicing via spliceosomeGO:004802430.019
regulation of cellular amino acid metabolic processGO:000652100.019
actin polymerization or depolymerizationGO:000815420.019
regulation of cell activationGO:005086510.019
g1 s transition of mitotic cell cycleGO:000008210.019
protein acetylationGO:000647320.019
compound eye developmentGO:004874920.019
single organism localizationGO:19025782250.019
positive regulation of gtp catabolic processGO:003312610.018
cellular ketone metabolic processGO:0042180110.018
protein metabolic processGO:00195381830.018
meiotic chromosome segregationGO:004513230.018
regulation of cellular ketone metabolic processGO:001056570.018
cellular amino acid metabolic processGO:000652070.018
protein secretionGO:000930610.018
regulation of signalingGO:00230512350.018
regulation of signal transductionGO:00099662250.018
regulation of nucleotide catabolic processGO:003081120.018
protein complex disassemblyGO:004324110.018
adult behaviorGO:003053420.018
embryonic organ developmentGO:00485683810.018
cell migrationGO:00164772370.018
regulation of purine nucleotide catabolic processGO:003312120.018
negative regulation of cellular processGO:00485232830.018
nucleic acid templated transcriptionGO:00976591810.018
small molecule metabolic processGO:0044281770.018
phagocytosis engulfmentGO:000691110.018
regulation of organelle assemblyGO:190211540.018
generation of neuronsGO:00486993850.018
regulation of biological qualityGO:00650082630.018
cellular component morphogenesisGO:00329893360.018
regulation of synapse organizationGO:005080730.018
carboxylic acid metabolic processGO:0019752220.018
rna biosynthetic processGO:00327741810.018
membrane invaginationGO:001032410.018
brain developmentGO:00074202930.018
head developmentGO:00603223030.018
heterocycle biosynthetic processGO:00181302150.017
neuroblast proliferationGO:000740520.017
regulation of nucleoside metabolic processGO:000911820.017
positive regulation of secretionGO:005104710.017
cell surface receptor signaling pathwayGO:00071663250.017
transportGO:00068102200.017
regulation of cell shapeGO:000836010.017
regulation of synaptic plasticityGO:004816710.017
cellular component movementGO:00069283350.017
cell projection morphogenesisGO:00488582440.017
nucleobase containing compound biosynthetic processGO:00346542050.017
spermatid developmentGO:000728620.017
cell morphogenesisGO:00009022890.017
internal protein amino acid acetylationGO:000647520.017
oxoacid metabolic processGO:0043436310.017
establishment of localizationGO:00512342440.017
regulation of biosynthetic processGO:00098892500.017
regulation of reproductive processGO:200024140.017
response to uvGO:000941130.017
positive regulation of notch signaling pathwayGO:004574730.017
aromatic compound biosynthetic processGO:00194382170.017
cellular response to topologically incorrect proteinGO:003596720.017
positive regulation of cytokine productionGO:000181920.017
regulation of gtp catabolic processGO:003312420.017
organonitrogen compound metabolic processGO:1901564740.017
peptidyl serine phosphorylationGO:001810510.017
spermatid differentiationGO:004851520.017
regulation of rna metabolic processGO:00512522240.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
single fertilizationGO:000733830.017
neuron differentiationGO:00301823530.017
organic acid metabolic processGO:0006082310.017
digestive system developmentGO:00551232890.017
cellular carbohydrate metabolic processGO:004426240.017
transcription dna templatedGO:00063511810.017
negative regulation of protein kinase activityGO:000646940.017
organelle organizationGO:00069962270.017
cellular respirationGO:004533330.017
macromolecular complex disassemblyGO:003298410.017
response to external stimulusGO:00096052640.017
peptidyl lysine acetylationGO:001839420.016
development of primary female sexual characteristicsGO:004654540.016
regulation of macromolecule biosynthetic processGO:00105562250.016
cell part morphogenesisGO:00329902460.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
ribonucleoside monophosphate catabolic processGO:000915840.016
positive regulation of purine nucleotide catabolic processGO:003312310.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
peptidyl serine modificationGO:001820920.016
protein dephosphorylationGO:000647030.016
regulation of alternative mrna splicing via spliceosomeGO:000038110.016
establishment of protein localization to plasma membraneGO:009000210.016
system processGO:00030081850.016
vasculature developmentGO:00019442780.016
cellular component biogenesisGO:00440851780.016
eye developmentGO:00016542770.016
regionalizationGO:00030022740.016
extrinsic apoptotic signaling pathwayGO:009719130.016
cellular response to chemical stimulusGO:00708871570.016
establishment of synaptic vesicle localizationGO:009748010.016
stem cell divisionGO:001714510.016
actin filament polymerizationGO:003004120.016
positive regulation of cytoskeleton organizationGO:005149530.016
synaptic growth at neuromuscular junctionGO:005112420.016
regulation of synapse assemblyGO:005196330.016
locomotor rhythmGO:004547530.016
atp catabolic processGO:000620040.016
regulation of protein polymerizationGO:003227120.016
exocytosisGO:000688710.016
positive regulation of nucleoside metabolic processGO:004597910.016
digestive tract morphogenesisGO:00485462310.015
sensory organ developmentGO:00074233930.015
cellular response to radiationGO:007147840.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
positive regulation of nucleotide catabolic processGO:003081310.015
i kappab kinase nf kappab signalingGO:000724940.015
blood vessel developmentGO:00015682460.015
cell motilityGO:00488702440.015
digestive tract developmentGO:00485652650.015
positive regulation of cellular amine metabolic processGO:003324000.015
protein acylationGO:004354330.015
regulation of rna biosynthetic processGO:20011412130.015
positive regulation of secretion by cellGO:190353210.015
regulation of transcription dna templatedGO:00063552130.015
regulation of cell projection assemblyGO:006049140.015
positive regulation of gtpase activityGO:004354710.015
chemosensory behaviorGO:000763510.015
protein polyubiquitinationGO:000020940.015
embryonic organ morphogenesisGO:00485622740.015
immune system processGO:00023762410.015
positive regulation of cell activationGO:005086710.015
regulation of multicellular organismal processGO:00512392770.015
secondary metabolic processGO:001974830.015
positive regulation of cell adhesionGO:004578510.015
cellular protein metabolic processGO:00442671290.015
internal peptidyl lysine acetylationGO:001839320.015
tissue remodelingGO:004877140.015
macroautophagyGO:001623610.015
single organism transportGO:00447652060.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
regulation of circadian rhythmGO:004275240.015
regulation of carbohydrate metabolic processGO:000610940.014
determination of bilateral symmetryGO:00098552040.014
chordate embryonic developmentGO:00430092710.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
heart developmentGO:00075073130.014
negative regulation of kinase activityGO:003367340.014
cellular component assemblyGO:00226071700.014
erk1 and erk2 cascadeGO:007037140.014
cellular amide metabolic processGO:004360340.014
regulation of gtpase activityGO:004308720.014
sequestering of metal ionGO:005123830.014
centrosome organizationGO:005129710.014
regulation of transporter activityGO:003240920.014
regulation of metal ion transportGO:001095940.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
response to alkaloidGO:004327920.014
mitotic dna integrity checkpointGO:004477440.014
specification of symmetryGO:00097992040.014
cytoskeleton dependent cytokinesisGO:006164030.014
cell projection organizationGO:00300302840.014
growthGO:00400071740.014
positive regulation of biological processGO:00485182530.014
single organism organelle organizationGO:19025891990.014
response to nutrientGO:000758430.014
response to organic substanceGO:00100331530.014
lateral inhibitionGO:004633110.014
response to carbohydrateGO:000974330.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
fertilizationGO:000956630.014
cellular response to lipopolysaccharideGO:007122230.014
er to golgi vesicle mediated transportGO:000688810.014
hemopoiesisGO:00300971830.014
developmental growthGO:00485891660.014
negative regulation of protein complex assemblyGO:003133310.013
localization of cellGO:00516742440.013
gastrulationGO:00073692080.013
cellular response to molecule of bacterial originGO:007121930.013
regulation of neural precursor cell proliferationGO:200017730.013
protein stabilizationGO:005082120.013
cell matrix adhesionGO:000716040.013
somatic stem cell maintenanceGO:003501910.013
endoplasmic reticulum unfolded protein responseGO:003096820.013
cellular response to biotic stimulusGO:007121630.013
embryo development ending in birth or egg hatchingGO:00097922710.013
regulation of developmental processGO:00507932470.013
synaptic vesicle transportGO:004848910.013
response to hydrogen peroxideGO:004254230.013
mitotic cell cycle embryonicGO:004544820.013
peptide transportGO:001583310.013
synaptic vesicle localizationGO:009747910.013
production of molecular mediator of immune responseGO:000244020.013
intracellular signal transductionGO:0035556850.013
response to monosaccharideGO:003428430.013
response to unfolded proteinGO:000698620.013
angiogenesisGO:00015251580.013
regulation of cellular protein catabolic processGO:190336210.013
translational initiationGO:000641330.013
regulation of protein bindingGO:004339330.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
negative regulation of sequestering of calcium ionGO:005128340.013
nuclear exportGO:005116810.013
startle responseGO:000196440.013
muscle structure developmentGO:00610611960.013
immune system developmentGO:00025201910.013
small molecule catabolic processGO:004428230.013
neuron developmentGO:00486662620.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
sequestering of calcium ionGO:005120830.012
transcription from rna polymerase ii promoterGO:0006366800.012
mitochondrial transportGO:000683920.012
interspecies interaction between organismsGO:004441940.012
regulation of stem cell differentiationGO:200073640.012
calcium ion transport into cytosolGO:006040230.012
purine nucleoside monophosphate catabolic processGO:000912840.012
apoptotic processGO:00069151160.012
negative regulation of cellular catabolic processGO:003133030.012
negative regulation of protein transportGO:005122430.012
microtubule organizing center organizationGO:003102310.012
nucleic acid transportGO:005065720.012
regulation of stem cell proliferationGO:007209120.012
er nucleus signaling pathwayGO:000698420.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
positive regulation of dna metabolic processGO:005105410.012
sleepGO:003043110.012
lamellipodium organizationGO:009758110.012
regulation of protein complex disassemblyGO:004324410.012
lamellipodium assemblyGO:003003210.012
response to hexoseGO:000974630.012
negative regulation of cytoplasmic transportGO:190365020.012
nucleoside monophosphate catabolic processGO:000912540.012
double strand break repairGO:000630230.012
regulation of cell deathGO:00109411030.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
germ line stem cell maintenanceGO:003071820.012
negative regulation of defense responseGO:003134820.012
regulation of autophagyGO:001050630.012
negative regulation of catabolic processGO:000989530.012
neurotransmitter transportGO:000683620.012
leukocyte proliferationGO:007066110.012
deathGO:00162651210.012
post embryonic organ developmentGO:004856940.012
developmental programmed cell deathGO:001062340.012
alternative mrna splicing via spliceosomeGO:000038010.012
regulation of programmed cell deathGO:00430671010.012
carbohydrate homeostasisGO:003350010.012
regulation of reactive oxygen species metabolic processGO:200037720.012
xenobiotic metabolic processGO:000680540.012
negative regulation of synapse assemblyGO:005196420.012
anterior posterior pattern specificationGO:00099521520.012
mitotic dna damage checkpointGO:004477340.012
positive regulation of chromatin modificationGO:190331010.012
negative regulation of mapk cascadeGO:004340940.012
sensory organ morphogenesisGO:00905962000.012
blood vessel morphogenesisGO:00485142160.012
camera type eye developmentGO:00430102220.012
cellular localizationGO:0051641970.012
positive regulation of stress activated mapk cascadeGO:003287430.012
regulation of organ growthGO:004662030.012
protein homooligomerizationGO:005126030.012
regulation of erk1 and erk2 cascadeGO:007037240.012
cilium morphogenesisGO:0060271850.012
regulation of blood pressureGO:000821710.012
macromolecule modificationGO:00434121110.012
female gonad developmentGO:000858540.012
homeostatic processGO:00425921420.012
negative regulation of map kinase activityGO:004340720.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
negative regulation of intracellular transportGO:003238730.012
female sex differentiationGO:004666040.011
regulation of apoptotic processGO:0042981980.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
positive regulation of cellular processGO:00485222010.011
regulation of sequestering of calcium ionGO:005128240.011
lipid catabolic processGO:001604240.011
negative regulation of protein localization to nucleusGO:190018120.011
response to glucoseGO:000974930.011
cell substrate junction assemblyGO:000704420.011
mononuclear cell proliferationGO:003294310.011
programmed cell deathGO:00125011190.011
ameboidal type cell migrationGO:00016671430.011
carbohydrate biosynthetic processGO:001605110.011
nucleobase containing compound transportGO:001593120.011
regulation of multicellular organismal developmentGO:20000262230.011
regulation of jak stat cascadeGO:004642530.011
sensory perception of chemical stimulusGO:000760630.011
cell substrate adhesionGO:003158940.011
vacuolar transportGO:000703420.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
cellular protein modification processGO:00064641000.011
multi organism processGO:00517041340.011
b cell activationGO:004211320.011
positive regulation of histone modificationGO:003105810.011
positive regulation of map kinase activityGO:004340630.011
positive regulation of protein complex assemblyGO:003133420.011
gland developmentGO:00487321430.011
spindle assemblyGO:005122520.011
organism emergence from protective structureGO:007168440.011
multi organism cellular processGO:004476420.011
alcohol biosynthetic processGO:004616520.011
protein targeting to membraneGO:000661210.011
tube closureGO:006060610.011
somatic muscle developmentGO:000752540.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
rna transportGO:005065820.011
cellular response to light stimulusGO:007148240.011
post golgi vesicle mediated transportGO:000689210.011
regulation of protein depolymerizationGO:190187910.011
regulation of ras gtpase activityGO:003231820.011
epithelial tube morphogenesisGO:00605621480.011
cellular response to unfolded proteinGO:003462020.011
neuron projection developmentGO:00311751800.011
positive regulation of leukocyte differentiationGO:190210710.011
neurotransmitter secretionGO:000726920.011
regulation of wound healingGO:006104120.011
viral processGO:001603210.011
cytosolic calcium ion transportGO:006040130.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
protein modification processGO:00362111000.011
hormone secretionGO:004687920.011
establishment of rna localizationGO:005123630.011
intracellular mrna localizationGO:000829810.011
response to external biotic stimulusGO:0043207970.011
g2 dna damage checkpointGO:003157230.011
dorsal ventral pattern formationGO:00099531250.011
positive regulation of protein polymerizationGO:003227320.011
centrosome cycleGO:000709810.011
cellular response to reactive oxygen speciesGO:003461420.011
determination of left right symmetryGO:00073681790.010
adherens junction organizationGO:003433240.010
dna templated transcription elongationGO:000635430.010
regulation of response to biotic stimulusGO:000283120.010
response to amino acidGO:004320020.010
response to biotic stimulusGO:0009607970.010
signal transduction in absence of ligandGO:003803410.010
positive regulation of i kappab kinase nf kappab signalingGO:004312330.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
regulation of dna templated transcription elongationGO:003278430.010
cell deathGO:00082191210.010
regulation of cellular component organizationGO:0051128860.010
negative regulation of cytokine productionGO:000181810.010
organelle assemblyGO:00709251100.010
negative regulation of multi organism processGO:004390130.010
regulation of muscle contractionGO:000693730.010
antimicrobial humoral responseGO:001973020.010
positive regulation of translationGO:004572710.010
peptidyl threonine phosphorylationGO:001810710.010
hormone transportGO:000991420.010
regulation of exocytosisGO:001715710.010
negative regulation of nuclear divisionGO:005178430.010
response to other organismGO:0051707970.010
cellular protein complex disassemblyGO:004362410.010
atp synthesis coupled electron transportGO:004277310.010

manba disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
nervous system diseaseDOID:86300.020
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
musculoskeletal system diseaseDOID:1700.013
disease of metabolismDOID:001466700.013
organ system cancerDOID:005068600.012
inherited metabolic disorderDOID:65500.010
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010