Danio rerio

13 known processes

ptprb

protein tyrosine phosphatase, receptor type, b

(Aliases: R-PTP-beta)

ptprb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sprouting angiogenesisGO:0002040530.711
embryonic organ developmentGO:00485683810.576
blood vessel developmentGO:00015682460.524
blood vessel morphogenesisGO:00485142160.487
cell surface receptor signaling pathwayGO:00071663250.394
positive regulation of cell matrix adhesionGO:000195410.374
regulation of cell shapeGO:000836010.322
regulation of multicellular organismal processGO:00512392770.314
vasculature developmentGO:00019442780.303
germ line stem cell divisionGO:004207810.297
regulation of endothelial cell proliferationGO:000193610.273
angiogenesisGO:00015251580.265
cell motilityGO:00488702440.255
vascular endothelial growth factor receptor signaling pathwayGO:0048010130.255
cellular component morphogenesisGO:00329893360.246
cell migrationGO:00164772370.231
organelle organizationGO:00069962270.228
embryo development ending in birth or egg hatchingGO:00097922710.224
maintenance of locationGO:005123540.214
localization of cellGO:00516742440.205
regulation of cell morphogenesisGO:0022604420.167
anterior posterior pattern specificationGO:00099521520.164
cellular component movementGO:00069283350.164
determination of bilateral symmetryGO:00098552040.162
cell morphogenesisGO:00009022890.158
generation of neuronsGO:00486993850.148
chordate embryonic developmentGO:00430092710.147
regulation of developmental processGO:00507932470.147
skeletal muscle organ developmentGO:0060538780.139
regionalizationGO:00030022740.137
embryonic organ morphogenesisGO:00485622740.136
organic cyclic compound metabolic processGO:19013603010.134
regulation of biological qualityGO:00650082630.123
regulation of cell matrix adhesionGO:000195210.121
response to external stimulusGO:00096052640.117
muscle cell differentiationGO:00426921390.108
adherens junction organizationGO:003433240.108
regulation of multicellular organism growthGO:004001440.107
purine nucleoside monophosphate catabolic processGO:000912840.106
positive regulation of cell substrate adhesionGO:001081110.106
sensory perception of chemical stimulusGO:000760630.104
cell morphogenesis involved in differentiationGO:00009041950.102
signal transductionGO:00071654550.099
negative regulation of biological processGO:00485193040.095
larval developmentGO:000216420.094
nitrogen compound metabolic processGO:00068073190.094
agingGO:000756820.094
synaptic growth at neuromuscular junctionGO:005112420.093
inorganic cation transmembrane transportGO:0098662500.093
regulation of synapse organizationGO:005080730.092
regulation of dendrite developmentGO:005077330.089
central nervous system developmentGO:00074173870.088
endothelial cell proliferationGO:0001935110.087
cell fate commitmentGO:0045165990.086
single organism organelle organizationGO:19025891990.086
cellular response to extracellular stimulusGO:003166820.084
cell substrate adhesionGO:003158940.083
regulation of cell substrate adhesionGO:001081010.083
regulation of epithelial cell proliferationGO:005067830.081
head developmentGO:00603223030.078
regulation of response to stimulusGO:00485832690.075
macromolecular complex subunit organizationGO:0043933740.074
eye developmentGO:00016542770.073
stem cell divisionGO:001714510.071
cell part morphogenesisGO:00329902460.070
tube morphogenesisGO:00352393490.070
regulation of macromolecule biosynthetic processGO:00105562250.069
cellular response to chemical stimulusGO:00708871570.068
oxoacid metabolic processGO:0043436310.068
regulation of multicellular organismal developmentGO:20000262230.067
single organism metabolic processGO:00447102170.065
positive regulation of muscle organ developmentGO:004863610.064
negative regulation of synapse assemblyGO:005196420.064
guanosine containing compound metabolic processGO:190106840.063
notochord developmentGO:0030903540.063
enzyme linked receptor protein signaling pathwayGO:00071671060.061
positive regulation of cellular component biogenesisGO:004408930.060
neuron differentiationGO:00301823530.060
sensory perceptionGO:0007600390.060
determination of left right symmetryGO:00073681790.060
growthGO:00400071740.059
cell projection assemblyGO:0030031640.058
positive regulation of epithelial cell proliferationGO:005067910.058
stem cell proliferationGO:007208940.058
brain developmentGO:00074202930.057
response to chemicalGO:00422213200.056
reflexGO:006000420.055
ovarian follicle developmentGO:000154120.055
cell projection morphogenesisGO:00488582440.054
heart developmentGO:00075073130.054
ameboidal type cell migrationGO:00016671430.051
morphogenesis of an epitheliumGO:00020093330.051
regulation of nucleobase containing compound metabolic processGO:00192192500.050
adult behaviorGO:003053420.050
modification dependent macromolecule catabolic processGO:004363230.050
somitogenesisGO:0001756870.049
small molecule metabolic processGO:0044281770.049
convergent extension involved in gastrulationGO:0060027710.049
response to stressGO:00069502630.049
mesenchyme developmentGO:00604851270.049
regulation of cellular macromolecule biosynthetic processGO:20001122220.048
regulation of cellular metabolic processGO:00313233200.048
cellular component assembly involved in morphogenesisGO:00109271070.047
regulation of cell growthGO:0001558290.047
positive regulation of map kinase activityGO:004340630.046
cellular nitrogen compound metabolic processGO:00346412900.046
segmentationGO:0035282970.046
response to nutrientGO:000758430.045
regulation of bindingGO:005109830.045
cellular response to external stimulusGO:007149620.045
cellular response to nutrient levelsGO:003166920.045
cell matrix adhesionGO:000716040.044
negative regulation of calcium dependent cell cell adhesionGO:004658810.044
ubiquitin dependent protein catabolic processGO:000651130.044
nuclear migrationGO:000709730.044
cation transmembrane transportGO:0098655650.044
cellular component assemblyGO:00226071700.043
regulation of synaptic growth at neuromuscular junctionGO:000858210.043
nucleobase containing compound metabolic processGO:00061392740.043
negative regulation of cellular processGO:00485232830.043
response to nutrient levelsGO:0031667100.040
regulation of macromolecule metabolic processGO:00602553170.040
multicellular organism growthGO:003526440.039
connective tissue developmentGO:0061448990.039
cellular component biogenesisGO:00440851780.039
organic acid metabolic processGO:0006082310.039
regulation of skeletal muscle tissue developmentGO:004864140.039
regulation of signalingGO:00230512350.038
meiotic cell cycle processGO:190304630.038
system processGO:00030081850.038
carbohydrate derivative metabolic processGO:1901135610.038
somite developmentGO:0061053960.038
nucleoside monophosphate catabolic processGO:000912540.038
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.038
neuroblast proliferationGO:000740520.037
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.037
central nervous system neuron developmentGO:0021954290.037
striated muscle cell developmentGO:00550021080.037
mitochondrion organizationGO:000700540.037
sensory organ developmentGO:00074233930.036
positive regulation of mesenchymal cell proliferationGO:000205310.036
cellular response to starvationGO:000926710.036
positive regulation of endothelial cell proliferationGO:000193810.035
regulation of embryonic developmentGO:0045995470.034
blood vessel endothelial cell migrationGO:0043534180.034
multi organism processGO:00517041340.034
muscle structure developmentGO:00610611960.034
cell substrate adherens junction assemblyGO:000704510.034
synaptic target recognitionGO:000803910.034
muscle organ developmentGO:00075171010.034
wound healingGO:0042060900.034
cell morphogenesis involved in neuron differentiationGO:00486671630.033
heterocycle metabolic processGO:00464832900.033
tissue remodelingGO:004877140.033
aromatic compound biosynthetic processGO:00194382170.033
positive regulation of cellular catabolic processGO:003133130.032
regulation of cellular amino acid metabolic processGO:000652100.032
developmental process involved in reproductionGO:0003006270.032
cellular aromatic compound metabolic processGO:00067252950.032
single organism reproductive processGO:0044702400.032
regulation of cell developmentGO:00602841000.032
positive regulation of catabolic processGO:000989640.031
maternal determination of anterior posterior axis embryoGO:000835840.031
actin cytoskeleton organizationGO:0030036630.031
heterocycle biosynthetic processGO:00181302150.031
endocrine hormone secretionGO:006098620.031
organonitrogen compound metabolic processGO:1901564740.031
guanosine containing compound catabolic processGO:190106920.031
purine ribonucleoside monophosphate catabolic processGO:000916940.031
protein homooligomerizationGO:005126030.031
cytokinesisGO:000091030.030
heart loopingGO:0001947940.030
entrainment of circadian clockGO:000964920.030
pronuclear migrationGO:003504610.029
embryonic hemopoiesisGO:0035162530.029
regulation of heart growthGO:006042020.029
positive regulation of striated muscle tissue developmentGO:004584410.029
muscle cell developmentGO:00550011150.029
regulation of anatomical structure morphogenesisGO:00226031300.029
endodermal cell fate determinationGO:000749320.029
regulation of cellular component organizationGO:0051128860.028
multi organism reproductive processGO:0044703360.028
developmental growthGO:00485891660.028
positive regulation of signalingGO:0023056560.028
g2 m transition of mitotic cell cycleGO:000008640.028
cellular nitrogen compound biosynthetic processGO:00442712180.028
regulation of dendrite morphogenesisGO:004881430.028
regulation of mesenchymal cell proliferationGO:001046410.027
regulation of calcium dependent cell cell adhesionGO:004658610.027
cell agingGO:000756920.027
cellular modified amino acid metabolic processGO:000657530.027
regulation of circadian rhythmGO:004275240.027
sensory organ morphogenesisGO:00905962000.027
locomotionGO:00400113130.026
cardiac cell fate commitmentGO:006091110.026
cell deathGO:00082191210.026
positive regulation of muscle tissue developmentGO:190186310.026
epithelial tube morphogenesisGO:00605621480.026
macromolecule biosynthetic processGO:00090592270.026
gastrulationGO:00073692080.026
cellular amine metabolic processGO:004410620.026
ventricular cardiac muscle tissue morphogenesisGO:005501020.026
developmental cell growthGO:0048588520.026
smooth muscle contractionGO:000693920.025
response to woundingGO:00096111160.025
positive regulation of stem cell proliferationGO:200064810.025
specification of symmetryGO:00097992040.025
inorganic ion transmembrane transportGO:0098660570.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
neuromuscular synaptic transmissionGO:000727420.025
rna biosynthetic processGO:00327741810.025
actin filament based processGO:0030029640.025
multicellular organismal signalingGO:0035637220.024
lipid storageGO:001991510.024
amine metabolic processGO:000930820.024
positive regulation of cell divisionGO:005178120.024
regulation of cellular biosynthetic processGO:00313262450.024
protein metabolic processGO:00195381830.024
multicellular organism reproductionGO:0032504350.024
activation of jun kinase activityGO:000725720.024
cellular macromolecule metabolic processGO:00442603910.023
regulation of vasculogenesisGO:200121210.023
response to organic substanceGO:00100331530.023
positive regulation of biological processGO:00485182530.023
single fertilizationGO:000733830.023
oocyte maturationGO:000155640.023
cell projection organizationGO:00300302840.023
regulation of organ growthGO:004662030.022
negative regulation of cellular biosynthetic processGO:0031327550.022
endocrine processGO:005088620.022
organelle localizationGO:0051640490.022
carboxylic acid metabolic processGO:0019752220.022
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.022
negative regulation of sequestering of calcium ionGO:005128340.022
camera type eye developmentGO:00430102220.022
immune system processGO:00023762410.022
neuron projection morphogenesisGO:00488121610.022
regulation of cell differentiationGO:00455951420.022
regulation of localizationGO:00328791040.022
axon developmentGO:00615641660.022
regulation of cellular component movementGO:0051270550.022
regulation of synapse assemblyGO:005196330.022
positive regulation of cellular amine metabolic processGO:003324000.022
heart morphogenesisGO:00030071560.022
hepaticobiliary system developmentGO:0061008980.022
response to corticosteroidGO:003196010.021
establishment of organelle localizationGO:0051656450.021
cytoskeleton organizationGO:0007010960.021
cardiac atrium developmentGO:000323040.021
regulation of neuron projection developmentGO:0010975400.021
response to light stimulusGO:0009416460.021
epithelial cell proliferationGO:0050673170.021
ventricular cardiac muscle tissue developmentGO:000322930.021
iron ion homeostasisGO:005507240.021
endocardial cushion formationGO:000327220.020
reproductive processGO:0022414400.020
determination of left right asymmetry in nervous systemGO:003554540.020
regulation of transcription from rna polymerase ii promoterGO:00063571140.020
embryonic heart tube developmentGO:00350501330.020
establishment of protein localization to organelleGO:007259440.020
phosphate containing compound metabolic processGO:00067961080.019
digestive tract developmentGO:00485652650.019
mononuclear cell migrationGO:007167410.019
positive regulation of cell adhesionGO:004578510.019
biological adhesionGO:0022610400.019
embryonic digestive tract morphogenesisGO:004855730.019
protein oligomerizationGO:005125970.019
ovulation cycle processGO:002260220.019
lymphangiogenesisGO:0001946250.019
negative regulation of chemotaxisGO:005092240.018
nuclear transportGO:005116940.018
negative regulation of biosynthetic processGO:0009890550.018
neuron projection developmentGO:00311751800.018
water homeostasisGO:003010440.018
skeletal muscle tissue developmentGO:0007519670.018
response to glucocorticoidGO:005138410.018
erk1 and erk2 cascadeGO:007037140.018
macromolecule modificationGO:00434121110.018
regulation of cellular ketone metabolic processGO:001056570.018
negative regulation of response to stimulusGO:00485851040.018
heart valve formationGO:000318840.018
dendrite guidanceGO:007098300.018
transportGO:00068102200.018
cellular process involved in reproduction in multicellular organismGO:0022412280.018
paraxial mesoderm morphogenesisGO:004834020.018
ribonucleotide metabolic processGO:0009259270.017
regulation of cellular amine metabolic processGO:003323800.017
circulatory system processGO:0003013870.017
cellular amino acid metabolic processGO:000652070.017
ion transmembrane transportGO:0034220910.017
response to other organismGO:0051707970.017
regulation of primary metabolic processGO:00800903110.017
reproductionGO:0000003400.017
regulation of erythrocyte differentiationGO:004564620.017
protein complex biogenesisGO:0070271300.017
atp catabolic processGO:000620040.017
ribonucleoside monophosphate catabolic processGO:000915840.017
deathGO:00162651210.017
regulation of phosphate metabolic processGO:0019220430.017
stem cell differentiationGO:00488631170.017
meiotic nuclear divisionGO:000712640.017
neuron developmentGO:00486662620.017
osteoclast developmentGO:003603510.017
regulation of protein catabolic processGO:004217610.017
regulation of endothelial cell differentiationGO:004560130.017
central nervous system formationGO:002155610.017
gtp catabolic processGO:000618420.017
cell cell signalingGO:0007267520.017
behaviorGO:0007610740.016
regulation of metabolic processGO:00192223590.016
appendage developmentGO:0048736800.016
cellular response to hypoxiaGO:007145610.016
extrinsic apoptotic signaling pathwayGO:009719130.016
cell proliferationGO:0008283800.016
regulation of transcription dna templatedGO:00063552130.016
phosphorus metabolic processGO:00067931090.016
rna metabolic processGO:00160702190.016
immune system developmentGO:00025201910.016
adherens junction assemblyGO:003433310.016
negative regulation of leukocyte migrationGO:000268630.016
ovulation cycleGO:004269820.016
cellular response to radiationGO:007147840.016
locomotory behaviorGO:0007626340.016
phagocytosisGO:000690930.016
proteasomal protein catabolic processGO:001049820.016
regulation of cardiac muscle tissue developmentGO:005502410.016
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.016
nucleobase containing small molecule metabolic processGO:0055086320.015
sexual reproductionGO:0019953360.015
regulation of skeletal muscle fiber developmentGO:004874220.015
muscle tissue developmentGO:00605371100.015
synaptic vesicle recyclingGO:003646510.015
cell adhesionGO:0007155400.015
transmembrane transportGO:00550851200.015
regulation of nitrogen compound metabolic processGO:00511712510.015
neural crest cell differentiationGO:0014033720.015
forebrain developmentGO:0030900960.015
modification dependent protein catabolic processGO:001994130.015
endothelial cell fate commitmentGO:006083930.015
cell cell junction organizationGO:0045216100.015
regulation of gene expressionGO:00104682650.015
response to abiotic stimulusGO:00096281220.015
regulation of cell morphogenesis involved in differentiationGO:0010769380.015
trabecula morphogenesisGO:006138320.015
mitotic dna integrity checkpointGO:004477440.015
apoptotic processGO:00069151160.015
autophagyGO:000691440.015
determination of left right asymmetry in diencephalonGO:003546240.014
response to organic cyclic compoundGO:0014070510.014
regulation of cytoplasmic transportGO:190364940.014
positive regulation of cell cycleGO:004578730.014
single organism localizationGO:19025782250.014
nucleus localizationGO:005164780.014
cellular response to light stimulusGO:007148240.014
mesenchymal cell differentiationGO:0048762870.014
chemical homeostasisGO:0048878490.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
centrosome duplicationGO:005129810.014
direct ossificationGO:003607230.014
taxisGO:00423301090.013
hatching gland developmentGO:004878530.013
embryonic limb morphogenesisGO:003032620.013
septum transversum developmentGO:000334340.013
notch signaling pathwayGO:0007219350.013
cellular response to organic substanceGO:00713101050.013
meiosis iGO:000712710.013
regulation of tube sizeGO:003515020.013
regulation of gtp catabolic processGO:003312420.013
negative regulation of macromolecule metabolic processGO:0010605760.013
regenerationGO:0031099910.013
striated muscle cell differentiationGO:00511461290.013
regulation of bmp signaling pathwayGO:0030510390.013
cellular ketone metabolic processGO:0042180110.013
response to oxygen levelsGO:0070482250.013
embryonic heart tube morphogenesisGO:00031431080.013
ectodermal cell fate specificationGO:000171520.013
regulation of rna biosynthetic processGO:20011412130.013
positive regulation of nucleoside metabolic processGO:004597910.013
bmp signaling pathwayGO:0030509520.013
regulation of developmental growthGO:0048638380.013
protein localization to nucleusGO:003450430.013
cellular iron ion homeostasisGO:000687930.013
positive regulation of transportGO:005105020.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.013
lateral ventricle developmentGO:002167010.013
multicellular organismal reproductive processGO:0048609350.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
transcription from rna polymerase ii promoterGO:0006366800.013
positive regulation of cytoskeleton organizationGO:005149530.013
outflow tract morphogenesisGO:000315110.012
positive regulation of retina development in camera type eyeGO:190286810.012
peptidyl serine phosphorylationGO:001810510.012
cellular protein catabolic processGO:004425740.012
response to drugGO:004249330.012
dorsal aorta morphogenesisGO:003591230.012
cell death in response to oxidative stressGO:003647320.012
protein complex subunit organizationGO:0071822460.012
lymphatic endothelial cell differentiationGO:006083610.012
epidermal cell fate specificationGO:000995740.012
blood vessel endothelial cell differentiationGO:006083720.012
axis specificationGO:0009798430.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
mesoderm formationGO:0001707430.012
ventricular system developmentGO:0021591120.012
negative regulation of apoptotic processGO:0043066550.012
regulation of membrane potentialGO:0042391230.012
female meiotic divisionGO:000714320.012
organic substance biosynthetic processGO:19015762890.012
signal transduction in absence of ligandGO:003803410.012
cell migration involved in gastrulationGO:0042074790.012
negative regulation of bmp signaling pathwayGO:0030514130.012
phototransductionGO:000760220.012
microtubule cytoskeleton organization involved in mitosisGO:190285010.012
programmed cell deathGO:00125011190.012
regulation of cellular response to oxidative stressGO:190040720.012
odontogenesis of dentin containing toothGO:004247510.012
skeletal system developmentGO:00015011810.012
regulation of establishment or maintenance of cell polarityGO:003287820.012
inner ear developmentGO:00488391260.012
spindle assemblyGO:005122520.012
negative regulation of developmental processGO:0051093650.012
negative regulation of epithelial cell proliferationGO:005068010.012
dorsal aorta developmentGO:003590740.011
aorta developmentGO:003590440.011
cellular protein metabolic processGO:00442671290.011
membrane fusionGO:006102520.011
regulation of nervous system developmentGO:0051960900.011
cytoplasm organizationGO:000702840.011
anterior posterior axis specificationGO:0009948200.011
megakaryocyte differentiationGO:003021910.011
atrioventricular valve formationGO:000319030.011
neurological system processGO:0050877620.011
negative regulation of gene expressionGO:0010629650.011
positive regulation of leukocyte chemotaxisGO:000269010.011
carbohydrate derivative biosynthetic processGO:1901137430.011
cell fate specificationGO:0001708680.011
g2 dna damage checkpointGO:003157230.011
digestive system developmentGO:00551232890.011
regulation of cell projection assemblyGO:006049140.011
cellular biosynthetic processGO:00442492860.011
mitotic sister chromatid cohesionGO:000706420.011
macrophage chemotaxisGO:004824630.011
cation homeostasisGO:0055080330.011
gtp metabolic processGO:004603940.011
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.011
homeostatic processGO:00425921420.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
negative regulation of mesodermal cell fate specificationGO:004266230.011
response to extracellular stimulusGO:0009991100.011
monovalent inorganic cation transportGO:0015672420.011
epithelial cell migrationGO:0010631250.011
regulation of programmed cell deathGO:00430671010.011
mitotic nuclear divisionGO:0007067180.011
regulation of wnt signaling pathwayGO:0030111530.011
collagen fibril organizationGO:003019910.011
regulation of cell communicationGO:00106462320.011
skeletal system morphogenesisGO:00487051020.011
nuclear importGO:005117030.010
regulation of dna templated transcription in response to stressGO:004362000.010
meiotic spindle organizationGO:000021210.010
organelle assemblyGO:00709251100.010
synaptic vesicle localizationGO:009747910.010
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.010
interaction with hostGO:005170140.010
myofibril assemblyGO:0030239480.010
organophosphate metabolic processGO:0019637370.010
ear developmentGO:00435831270.010
regulation of filopodium assemblyGO:005148920.010
lamellipodium organizationGO:009758110.010
gland developmentGO:00487321430.010
cellular macromolecule biosynthetic processGO:00346452240.010
regulation of behaviorGO:0050795240.010
endocardial cushion morphogenesisGO:000320330.010
response to uvGO:000941130.010
regulation of phosphorus metabolic processGO:0051174430.010

ptprb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.117
nervous system diseaseDOID:86300.052
musculoskeletal system diseaseDOID:1700.029
muscular diseaseDOID:008000000.029
inherited metabolic disorderDOID:65500.027
disease of metabolismDOID:001466700.027
lysosomal storage diseaseDOID:321100.027
immune system diseaseDOID:291400.025
muscle tissue diseaseDOID:6600.022
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
intestinal cancerDOID:1015500.014
large intestine cancerDOID:567200.014
organ system cancerDOID:005068600.014
gastrointestinal system cancerDOID:311900.014
lipid storage diseaseDOID:945500.010