Danio rerio

0 known processes

unc5db

unc-5 homolog Db (C. elegans)

(Aliases: si:dkeyp-38h2.6)

unc5db biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
brain developmentGO:00074202930.163
central nervous system developmentGO:00074173870.161
cellular component movementGO:00069283350.121
nucleocytoplasmic transportGO:000691340.112
cell morphogenesis involved in differentiationGO:00009041950.097
embryonic organ developmentGO:00485683810.090
cellular amide metabolic processGO:004360340.090
protein localization to nucleusGO:003450430.090
protein targeting to nucleusGO:004474430.089
locomotionGO:00400113130.089
neuron developmentGO:00486662620.088
neuron differentiationGO:00301823530.082
signal transductionGO:00071654550.082
organic cyclic compound metabolic processGO:19013603010.082
single organism nuclear importGO:190259330.081
cellular component morphogenesisGO:00329893360.081
localization of cellGO:00516742440.076
response to organic substanceGO:00100331530.076
hematopoietic or lymphoid organ developmentGO:00485341910.076
establishment of protein localization to organelleGO:007259440.074
cell projection morphogenesisGO:00488582440.072
cellular response to external stimulusGO:007149620.072
tube morphogenesisGO:00352393490.071
vasculature developmentGO:00019442780.067
nuclear importGO:005117030.066
organic substance biosynthetic processGO:19015762890.066
cell motilityGO:00488702440.066
head developmentGO:00603223030.065
axon developmentGO:00615641660.065
protein import into nucleusGO:000660630.064
somatic stem cell maintenanceGO:003501910.062
embryonic organ morphogenesisGO:00485622740.062
cellular macromolecule metabolic processGO:00442603910.062
protein importGO:001703830.061
stem cell proliferationGO:007208940.059
larval developmentGO:000216420.059
neuroblast proliferationGO:000740520.059
regulation of protein import into nucleusGO:004230620.059
response to external stimulusGO:00096052640.058
positive regulation of transportGO:005105020.057
immune system processGO:00023762410.057
regulation of macromolecule metabolic processGO:00602553170.057
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.056
regionalizationGO:00030022740.056
developmental cell growthGO:0048588520.056
positive regulation of catabolic processGO:000989640.056
regulation of establishment of protein localizationGO:007020140.054
stem cell differentiationGO:00488631170.054
guanosine containing compound metabolic processGO:190106840.054
cellular nitrogen compound metabolic processGO:00346412900.053
cellular biosynthetic processGO:00442492860.053
heterocycle biosynthetic processGO:00181302150.053
nucleic acid templated transcriptionGO:00976591810.053
regulation of nitrogen compound metabolic processGO:00511712510.052
regulation of protein localization to nucleusGO:190018020.052
regulation of protein targetingGO:190353320.052
peptide metabolic processGO:000651810.052
female gonad developmentGO:000858540.052
regulation of nucleocytoplasmic transportGO:004682220.052
neuron neuron synaptic transmissionGO:000727010.051
regulation of developmental processGO:00507932470.051
cellular macromolecule biosynthetic processGO:00346452240.051
specification of symmetryGO:00097992040.051
dorsal ventral pattern formationGO:00099531250.051
cell migrationGO:00164772370.050
immune system developmentGO:00025201910.050
morphogenesis of an epitheliumGO:00020093330.049
establishment of localizationGO:00512342440.049
determination of bilateral symmetryGO:00098552040.048
autophagyGO:000691440.048
cellular aromatic compound metabolic processGO:00067252950.048
nitrogen compound metabolic processGO:00068073190.048
development of primary female sexual characteristicsGO:004654540.046
regulation of intracellular protein transportGO:003315730.046
cellular response to nutrient levelsGO:003166920.046
gtp catabolic processGO:000618420.046
cell surface receptor signaling pathwayGO:00071663250.045
regulation of metabolic processGO:00192223590.045
cell part morphogenesisGO:00329902460.045
female sex differentiationGO:004666040.044
regulation of nucleobase containing compound metabolic processGO:00192192500.044
cellular response to extracellular stimulusGO:003166820.044
regulation of protein transportGO:005122330.043
gastrulationGO:00073692080.043
regulation of cell shapeGO:000836010.043
digestive system developmentGO:00551232890.043
synaptic target recognitionGO:000803910.043
blood vessel morphogenesisGO:00485142160.042
primary neural tube formationGO:001402010.042
regulation of nucleotide catabolic processGO:003081120.042
sensory organ developmentGO:00074233930.042
positive regulation of cellular catabolic processGO:003133130.042
gene expressionGO:00104672520.042
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.042
positive regulation of stress activated mapk cascadeGO:003287430.041
axon extensionGO:0048675450.041
mesenchymal cell differentiationGO:0048762870.041
organonitrogen compound metabolic processGO:1901564740.041
phagocytosisGO:000690930.040
skeletal system developmentGO:00015011810.040
axon guidanceGO:0007411860.039
i kappab kinase nf kappab signalingGO:000724940.039
transcription dna templatedGO:00063511810.039
cell morphogenesisGO:00009022890.039
regulation of primary metabolic processGO:00800903110.039
neuron projection extensionGO:1990138450.039
rna metabolic processGO:00160702190.039
positive regulation of biological processGO:00485182530.039
embryo development ending in birth or egg hatchingGO:00097922710.038
maintenance of locationGO:005123540.038
nuclear transportGO:005116940.038
generation of neuronsGO:00486993850.038
extrinsic apoptotic signaling pathwayGO:009719130.038
cellular response to starvationGO:000926710.037
embryonic cranial skeleton morphogenesisGO:0048701900.037
regulation of response to biotic stimulusGO:000283120.037
guanosine containing compound catabolic processGO:190106920.037
negative regulation of biological processGO:00485193040.037
eye developmentGO:00016542770.036
determination of left right symmetryGO:00073681790.036
cell projection organizationGO:00300302840.036
axonogenesisGO:00074091520.036
negative regulation of cytoplasmic transportGO:190365020.036
regulation of gene expressionGO:00104682650.035
regulation of signalingGO:00230512350.035
blood vessel developmentGO:00015682460.035
wnt signaling pathway planar cell polarity pathwayGO:006007140.035
nucleobase containing compound metabolic processGO:00061392740.035
embryonic heart tube developmentGO:00350501330.035
positive regulation of cellular processGO:00485222010.034
agingGO:000756820.034
gtp metabolic processGO:004603940.034
regulation of nucleic acid templated transcriptionGO:19035062130.034
cellular nitrogen compound biosynthetic processGO:00442712180.034
regulation of gtp catabolic processGO:003312420.034
stem cell maintenanceGO:001982740.034
ameboidal type cell migrationGO:00016671430.033
tube closureGO:006060610.033
cell morphogenesis involved in neuron differentiationGO:00486671630.033
neuron projection developmentGO:00311751800.033
regulation of production of molecular mediator of immune responseGO:000270010.032
mesenchymal cell developmentGO:0014031780.032
response to transition metal nanoparticleGO:1990267280.032
positive regulation of cell cycleGO:004578730.032
hemopoiesisGO:00300971830.031
regulation of rna metabolic processGO:00512522240.031
response to chemicalGO:00422213200.031
regulation of biosynthetic processGO:00098892500.031
liver developmentGO:0001889960.031
mesenchyme developmentGO:00604851270.031
secondary metabolic processGO:001974830.031
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.030
negative regulation of cellular processGO:00485232830.030
nucleobase containing compound biosynthetic processGO:00346542050.030
regulation of nucleoside metabolic processGO:000911820.030
nuclear migrationGO:000709730.030
single organism metabolic processGO:00447102170.029
cognitionGO:005089010.029
macromolecule biosynthetic processGO:00090592270.029
regulation of protein ubiquitinationGO:003139630.029
negative regulation of intracellular transportGO:003238730.029
developmental growthGO:00485891660.029
regulation of cytoplasmic transportGO:190364940.029
regulation of purine nucleotide catabolic processGO:003312120.028
regulation of cellular metabolic processGO:00313233200.028
nucleic acid metabolic processGO:00903042440.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
lateral line system developmentGO:0048925760.028
camera type eye developmentGO:00430102220.028
regulation of multicellular organismal processGO:00512392770.028
cellular protein metabolic processGO:00442671290.028
protein metabolic processGO:00195381830.028
embryonic skeletal system morphogenesisGO:0048704930.027
convergent extensionGO:00600261180.027
organelle organizationGO:00069962270.027
angiogenesisGO:00015251580.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.027
amine metabolic processGO:000930820.027
inner ear developmentGO:00488391260.027
developmental growth involved in morphogenesisGO:0060560860.027
chordate embryonic developmentGO:00430092710.027
digestive tract developmentGO:00485652650.027
cellular protein catabolic processGO:004425740.027
positive regulation of jnk cascadeGO:004633030.026
biosynthetic processGO:00090582940.026
negative regulation of cellular catabolic processGO:003133030.026
negative regulation of protein localization to nucleusGO:190018120.026
peptide transportGO:001583310.026
hepaticobiliary system developmentGO:0061008980.026
small molecule metabolic processGO:0044281770.025
myeloid cell differentiationGO:0030099860.025
forebrain developmentGO:0030900960.025
regulation of epithelial cell proliferationGO:005067830.025
cell migration involved in gastrulationGO:0042074790.025
determination of heart left right asymmetryGO:00613711170.025
regulation of localizationGO:00328791040.025
heterocycle metabolic processGO:00464832900.025
heart loopingGO:0001947940.025
regulation of cellular amine metabolic processGO:003323800.025
epithelial tube morphogenesisGO:00605621480.025
regulation of neuron projection developmentGO:0010975400.025
positive regulation of immune effector processGO:000269930.025
antimicrobial humoral responseGO:001973020.025
response to carbohydrateGO:000974330.024
membrane invaginationGO:001032410.024
enzyme linked receptor protein signaling pathwayGO:00071671060.024
outflow tract morphogenesisGO:000315110.024
regulation of rna biosynthetic processGO:20011412130.024
organic cyclic compound biosynthetic processGO:19013622230.024
response to alkaloidGO:004327920.024
embryonic skeletal system developmentGO:0048706970.024
embryonic heart tube morphogenesisGO:00031431080.024
cilium assemblyGO:0042384580.024
regulation of macromolecule biosynthetic processGO:00105562250.024
eye morphogenesisGO:00485921440.023
neuron migrationGO:0001764220.023
production of molecular mediator of immune responseGO:000244020.023
regulation of stem cell proliferationGO:007209120.023
negative regulation of catabolic processGO:000989530.023
cell substrate adhesionGO:003158940.023
regulation of reproductive processGO:200024140.023
regulation of protein catabolic processGO:004217610.023
neuron projection morphogenesisGO:00488121610.023
skeletal system morphogenesisGO:00487051020.023
positive regulation of purine nucleotide catabolic processGO:003312310.023
regulation of cellular component movementGO:0051270550.023
regulation of neurogenesisGO:0050767870.023
organic acid metabolic processGO:0006082310.023
digestive tract morphogenesisGO:00485462310.023
post embryonic organ developmentGO:004856940.022
regulation of axonogenesisGO:0050770320.022
positive regulation of i kappab kinase nf kappab signalingGO:004312330.022
regulation of multicellular organismal developmentGO:20000262230.022
protein secretionGO:000930610.022
single organism localizationGO:19025782250.022
cell growthGO:0016049570.022
compound eye developmentGO:004874920.022
ubiquitin dependent protein catabolic processGO:000651130.022
regulation of extrinsic apoptotic signaling pathwayGO:200123630.022
lateral line developmentGO:0048882660.022
transcription from rna polymerase ii promoterGO:0006366800.022
cartilage developmentGO:0051216960.022
regulation of collateral sprouting in absence of injuryGO:004869640.022
protein modification processGO:00362111000.022
central nervous system neuron differentiationGO:0021953740.022
amide biosynthetic processGO:004360410.021
negative regulation of intracellular protein transportGO:009031730.021
regulation of anatomical structure morphogenesisGO:00226031300.021
proteolysis involved in cellular protein catabolic processGO:005160330.021
apoptotic processGO:00069151160.021
negative regulation of nuclear divisionGO:005178430.021
sensory system developmentGO:0048880760.021
negative regulation of nucleocytoplasmic transportGO:004682320.021
transportGO:00068102200.021
regulation of nervous system developmentGO:0051960900.021
response to drugGO:004249330.021
notochord developmentGO:0030903540.021
positive regulation of nucleoside metabolic processGO:004597910.021
regulation of cell differentiationGO:00455951420.021
regulation of multicellular organism growthGO:004001440.021
positive regulation of cellular biosynthetic processGO:0031328680.021
cellular response to molecule of bacterial originGO:007121930.021
modification dependent macromolecule catabolic processGO:004363230.020
optic placode formation involved in camera type eye formationGO:004661930.020
regulation of locomotionGO:0040012550.020
system processGO:00030081850.020
response to corticosteroidGO:003196010.020
cellular component assembly involved in morphogenesisGO:00109271070.020
response to other organismGO:0051707970.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
cellular localizationGO:0051641970.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.020
lateral inhibitionGO:004633110.020
regulation of neuron differentiationGO:0045664560.020
wnt signaling pathwayGO:0016055800.020
xenobiotic metabolic processGO:000680540.020
hormone secretionGO:004687920.020
cellular amine metabolic processGO:004410620.020
regulation of cell morphogenesisGO:0022604420.020
tissue remodelingGO:004877140.020
centrosome organizationGO:005129710.020
heart developmentGO:00075073130.019
negative regulation of protein transportGO:005122430.019
macromolecule modificationGO:00434121110.019
multicellular organism growthGO:003526440.019
neural crest cell differentiationGO:0014033720.019
regulation of cell communicationGO:00106462320.019
rna biosynthetic processGO:00327741810.019
carboxylic acid metabolic processGO:0019752220.019
regulation of autophagyGO:001050630.019
cytoskeleton organizationGO:0007010960.019
positive regulation of secretionGO:005104710.019
microtubule organizing center organizationGO:003102310.019
canonical wnt signaling pathwayGO:0060070480.019
melanin metabolic processGO:000658220.019
sequestering of metal ionGO:005123830.019
positive regulation of cytosolic calcium ion concentrationGO:000720440.019
regulation of carbohydrate metabolic processGO:000610940.019
regulation of cell morphogenesis involved in differentiationGO:0010769380.019
regulation of transmembrane transporter activityGO:002289820.019
proteasomal protein catabolic processGO:001049820.019
regulation of phosphorus metabolic processGO:0051174430.019
oxoacid metabolic processGO:0043436310.018
segmentationGO:0035282970.018
regulation of synapse organizationGO:005080730.018
pancreas developmentGO:0031016840.018
sensory perception of chemical stimulusGO:000760630.018
regulation of biological qualityGO:00650082630.018
epithalamus developmentGO:0021538100.018
positive regulation of nucleotide catabolic processGO:003081310.018
reactive oxygen species biosynthetic processGO:190340910.018
diencephalon developmentGO:0021536580.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
regulation of ion transmembrane transporter activityGO:003241220.018
purine containing compound metabolic processGO:0072521290.018
positive regulation of nitrogen compound metabolic processGO:0051173690.018
regulation of dendrite developmentGO:005077330.018
regulation of cell deathGO:00109411030.018
embryonic camera type eye developmentGO:0031076290.018
reactive nitrogen species metabolic processGO:200105700.018
startle responseGO:000196440.018
sprouting angiogenesisGO:0002040530.018
phagocytosis engulfmentGO:000691110.018
gastrulation with mouth forming secondGO:0001702440.018
regulation of transporter activityGO:003240920.018
positive regulation of canonical wnt signaling pathwayGO:009026340.017
cellular ketone metabolic processGO:0042180110.017
regulation of stem cell differentiationGO:200073640.017
tissue regenerationGO:0042246740.017
regulation of cellular biosynthetic processGO:00313262450.017
negative regulation of protein import into nucleusGO:004230820.017
cellular protein modification processGO:00064641000.017
negative regulation of protein phosphorylationGO:000193340.017
regulation of programmed cell deathGO:00430671010.017
cell deathGO:00082191210.017
regulation of cell activationGO:005086510.017
regulation of glial cell differentiationGO:004568540.017
positive regulation of secretion by cellGO:190353210.017
ear developmentGO:00435831270.017
negative regulation of signalingGO:0023057960.017
cell matrix adhesionGO:000716040.017
regulation of cellular amino acid metabolic processGO:000652100.017
neural crest cell developmentGO:0014032620.017
regulation of gtpase activityGO:004308720.017
regulation of cytokine productionGO:000181730.016
response to stressGO:00069502630.016
taxisGO:00423301090.016
centrosome localizationGO:005164210.016
mesoderm developmentGO:0007498880.016
macromolecule localizationGO:0033036540.016
exocytosisGO:000688710.016
neuron projection guidanceGO:0097485860.016
meiotic nuclear divisionGO:000712640.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
regulation of signal transductionGO:00099662250.016
determination of dorsal ventral asymmetryGO:0048262340.016
non canonical wnt signaling pathwayGO:0035567130.016
response to nutrientGO:000758430.016
collateral sprouting in absence of injuryGO:004866940.016
phosphorus metabolic processGO:00067931090.016
response to metal ionGO:0010038340.016
wound healingGO:0042060900.016
chemotaxisGO:00069351040.016
positive regulation of epithelial cell proliferationGO:005067910.016
protein complex localizationGO:003150310.015
multi organism processGO:00517041340.015
regulation of dendrite morphogenesisGO:004881430.015
cellular amino acid metabolic processGO:000652070.015
regulation of protein bindingGO:004339330.015
response to monosaccharideGO:003428430.015
peptidyl serine phosphorylationGO:001810510.015
regulation of molecular functionGO:0065009700.015
regulation of cellular ketone metabolic processGO:001056570.015
interferon beta productionGO:003260810.015
regulation of cell motilityGO:2000145460.015
regulation of transcription dna templatedGO:00063552130.015
cilium morphogenesisGO:0060271850.015
negative regulation of kinase activityGO:003367340.015
connective tissue developmentGO:0061448990.015
regulation of cellular protein catabolic processGO:190336210.015
regulation of cell projection organizationGO:0031344440.015
catabolic processGO:0009056320.015
convergent extension involved in gastrulationGO:0060027710.015
muscle structure developmentGO:00610611960.015
positive regulation of cellular component biogenesisGO:004408930.015
hindbrain developmentGO:0030902910.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
regulation of cell growthGO:0001558290.015
cell fate commitmentGO:0045165990.014
phosphate containing compound metabolic processGO:00067961080.014
regulation of apoptotic processGO:0042981980.014
sensory organ morphogenesisGO:00905962000.014
leukocyte proliferationGO:007066110.014
embryonic skeletal joint developmentGO:007249830.014
somatic muscle developmentGO:000752540.014
toll like receptor signaling pathwayGO:000222440.014
cellular response to xenobiotic stimulusGO:0071466350.014
positive regulation of cell adhesionGO:004578510.014
gland developmentGO:00487321430.014
negative regulation of protein kinase activityGO:000646940.014
organelle fusionGO:004828430.014
mitochondrion organizationGO:000700540.014
cellular component disassemblyGO:002241110.014
nephron tubule morphogenesisGO:007207810.014
positive regulation of gtp catabolic processGO:003312610.014
organelle assemblyGO:00709251100.014
thrombocyte differentiationGO:000257440.014
epithelial cell proliferation involved in liver morphogenesisGO:007257520.014
growthGO:00400071740.014
carbohydrate homeostasisGO:003350010.014
carbohydrate derivative metabolic processGO:1901135610.014
neurotransmitter transportGO:000683620.014
regulation of cell developmentGO:00602841000.014
regulation of response to external stimulusGO:0032101310.014
neurological system processGO:0050877620.014
regulation of sequestering of calcium ionGO:005128240.014
deathGO:00162651210.014
lipid catabolic processGO:001604240.014
stem cell developmentGO:0048864820.014
positive regulation of gtpase activityGO:004354710.013
positive regulation of cellular metabolic processGO:0031325940.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
negative regulation of defense responseGO:003134820.013
regulation of mrna processingGO:005068430.013
positive regulation of macromolecule metabolic processGO:0010604930.013
positive regulation of gene expressionGO:0010628710.013
cytosolic calcium ion transportGO:006040130.013
positive regulation of neuron apoptotic processGO:004352510.013
positive regulation of cell activationGO:005086710.013
centrosome cycleGO:000709810.013
cilium organizationGO:0044782710.013
positive regulation of neuron deathGO:190121610.013
actomyosin structure organizationGO:0031032530.013
actin cytoskeleton organizationGO:0030036630.013
protein polyubiquitinationGO:000020940.013
catechol containing compound metabolic processGO:000971220.013
optic placode formationGO:000174340.013
spinal cord anterior posterior patterningGO:002151210.013
regulation of hormone secretionGO:004688320.013
regulation of tube sizeGO:003515020.013
regulation of cell substrate adhesionGO:001081010.013
mediolateral intercalationGO:006003130.013
regulation of protein complex assemblyGO:004325430.013
organonitrogen compound biosynthetic processGO:1901566470.013
macroautophagyGO:001623610.013
meiotic cell cycle processGO:190304630.013
establishment of localization in cellGO:0051649770.013
lipid storageGO:001991510.013
regulation of synaptic plasticityGO:004816710.013
negative regulation of map kinase activityGO:004340720.013
negative regulation of apoptotic processGO:0043066550.013
sequestering of calcium ionGO:005120830.013
intracellular signal transductionGO:0035556850.013
positive regulation of cytoskeleton organizationGO:005149530.013
nephron morphogenesisGO:007202820.012
cell proliferationGO:0008283800.012
b cell activationGO:004211320.012
negative regulation of mitosisGO:004583930.012
response to bacteriumGO:0009617580.012
negative regulation of autophagyGO:001050710.012
spinal cord developmentGO:0021510460.012
skin developmentGO:0043588540.012
cellular component biogenesisGO:00440851780.012
positive regulation of cytokine productionGO:000181920.012
single organism organelle organizationGO:19025891990.012
rna localizationGO:000640340.012
negative regulation of canonical wnt signaling pathwayGO:0090090210.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
regulation of ras gtpase activityGO:003231820.012
mononuclear cell proliferationGO:003294310.012
proximal distal pattern formationGO:000995410.012
regulation of bindingGO:005109830.012
regulation of sequence specific dna binding transcription factor activityGO:005109090.012
muscle cell differentiationGO:00426921390.012
regulation of neural precursor cell proliferationGO:200017730.012
forebrain regionalizationGO:002187140.012
response to cadmium ionGO:0046686140.012
eye field cell fate commitment involved in camera type eye formationGO:006089830.012
neuron deathGO:0070997210.012
positive regulation of metabolic processGO:00098931080.012
single organism cellular localizationGO:1902580460.011
programmed cell deathGO:00125011190.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
defense response to other organismGO:0098542330.011
positive regulation of striated muscle cell differentiationGO:005115510.011
epibolyGO:0090504410.011
response to glucocorticoidGO:005138410.011
negative regulation of cell communicationGO:0010648960.011

unc5db disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
disease of cellular proliferationDOID:1456600.016
musculoskeletal system diseaseDOID:1700.016
nervous system diseaseDOID:86300.014
cardiovascular system diseaseDOID:128700.014
cancerDOID:16200.014
organ system cancerDOID:005068600.012