Danio rerio

21 known processes

agr2

anterior gradient homolog 2 (Xenopus laevis)

(Aliases: MGC112187,zgc:112187,wu:fj29g05)

agr2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular sodium ion homeostasisGO:000688310.489
sensory organ developmentGO:00074233930.368
single organism localizationGO:19025782250.283
Mouse
amide transportGO:0042886120.282
regulation of sodium ion transportGO:000202820.279
regulation of metal ion transportGO:001095940.278
membrane repolarizationGO:008600920.257
inorganic ion transmembrane transportGO:0098660570.248
response to chemicalGO:00422213200.207
purine nucleoside monophosphate catabolic processGO:000912840.207
nucleoside monophosphate catabolic processGO:000912540.191
peptide transportGO:001583310.186
inorganic cation transmembrane transportGO:0098662500.186
negative regulation of heart contractionGO:004582220.180
regulation of cellular metabolic processGO:00313233200.176
larval developmentGO:000216420.173
response to abiotic stimulusGO:00096281220.168
regulation of metabolic processGO:00192223590.166
response to oxygen containing compoundGO:1901700550.160
agingGO:000756820.155
purine ribonucleoside monophosphate catabolic processGO:000916940.151
specification of organ axis polarityGO:001008420.148
brain developmentGO:00074202930.141
positive regulation of cellular processGO:00485222010.135
specification of axis polarityGO:006500140.134
positive regulation of blood circulationGO:190352420.131
organonitrogen compound metabolic processGO:1901564740.129
positive regulation of transportGO:005105020.129
negative regulation of blood circulationGO:190352320.125
sodium ion transportGO:0006814240.116
transmembrane transportGO:00550851200.113
transportGO:00068102200.108
Mouse
response to lipidGO:0033993600.104
establishment of endothelial barrierGO:006102830.100
response to biotic stimulusGO:0009607970.098
nitrogen compound transportGO:0071705230.097
nucleobase containing compound metabolic processGO:00061392740.094
ribonucleoside monophosphate catabolic processGO:000915840.091
tube morphogenesisGO:00352393490.091
adult behaviorGO:003053420.090
response to nutrientGO:000758430.088
regulation of cardiac muscle contractionGO:005511720.085
heterocycle metabolic processGO:00464832900.084
membrane hyperpolarizationGO:006008110.082
leukocyte proliferationGO:007066110.080
metal ion transportGO:0030001580.080
atp catabolic processGO:000620040.078
negative regulation of metabolic processGO:0009892860.078
cell migrationGO:00164772370.075
response to drugGO:004249330.073
embryonic organ developmentGO:00485683810.072
single organism metabolic processGO:00447102170.069
cell migration involved in heart formationGO:0060974100.066
cellular response to external stimulusGO:007149620.065
regulation of primary metabolic processGO:00800903110.064
morphogenesis of an epitheliumGO:00020093330.059
collagen biosynthetic processGO:003296420.059
cellular response to lipidGO:0071396390.058
system processGO:00030081850.058
homeostatic processGO:00425921420.056
regulation of blood pressureGO:000821710.056
cation transmembrane transportGO:0098655650.055
glucocorticoid metabolic processGO:000821120.054
positive regulation of heart contractionGO:004582320.053
cellular aromatic compound metabolic processGO:00067252950.052
regulation of localizationGO:00328791040.051
positive regulation of biological processGO:00485182530.050
monovalent inorganic cation transportGO:0015672420.050
protein localization to nucleusGO:003450430.049
multi organism reproductive processGO:0044703360.049
developmental growthGO:00485891660.048
regulation of cytoplasmic transportGO:190364940.048
polyol transportGO:001579170.046
nitrogen compound metabolic processGO:00068073190.046
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.045
phosphate containing compound metabolic processGO:00067961080.045
regulation of striated muscle contractionGO:000694220.045
angiogenesisGO:00015251580.043
vascular endothelial growth factor receptor signaling pathwayGO:0048010130.042
negative regulation of multicellular organismal processGO:0051241690.042
cellular response to chemical stimulusGO:00708871570.042
multicellular organismal macromolecule metabolic processGO:004425920.042
regulation of extrinsic apoptotic signaling pathwayGO:200123630.041
regulation of establishment of protein localizationGO:007020140.041
regulation of actin filament based movementGO:190311510.040
regulation of erk1 and erk2 cascadeGO:007037240.040
ear developmentGO:00435831270.040
establishment of localizationGO:00512342440.040
Mouse
response to temperature stimulusGO:0009266150.040
regulation of multicellular organism growthGO:004001440.040
locomotionGO:00400113130.039
hormone metabolic processGO:0042445190.039
blood vessel developmentGO:00015682460.039
fluid transportGO:0042044170.039
lipid digestionGO:004424130.039
neural tube patterningGO:0021532330.039
negative regulation of map kinase activityGO:004340720.039
embryo development ending in birth or egg hatchingGO:00097922710.038
direct ossificationGO:003607230.038
response to radiationGO:0009314510.037
mononuclear cell proliferationGO:003294310.037
synaptic growth at neuromuscular junctionGO:005112420.037
response to organic substanceGO:00100331530.037
lateral line developmentGO:0048882660.037
lateral line system developmentGO:0048925760.037
small molecule metabolic processGO:0044281770.037
negative regulation of i kappab kinase nf kappab signalingGO:004312410.037
cell cell signalingGO:0007267520.036
cellular component biogenesisGO:00440851780.036
regulation of ion transportGO:0043269220.035
osteoclast developmentGO:003603510.035
regulation of hormone levelsGO:0010817210.035
response to endogenous stimulusGO:0009719830.035
positive regulation of protein polymerizationGO:003227320.035
response to corticosteroidGO:003196010.034
cardiac muscle cell contractionGO:008600310.034
cellular response to organic cyclic compoundGO:0071407380.034
ion transportGO:00068111140.034
intramembranous ossificationGO:000195730.034
hormone transportGO:000991420.033
water transportGO:0006833150.033
cell morphogenesisGO:00009022890.033
regulation of reproductive processGO:200024140.033
response to external stimulusGO:00096052640.033
otolith developmentGO:0048840320.032
renal absorptionGO:007029310.031
regulation of intracellular protein transportGO:003315730.031
cell motilityGO:00488702440.031
skeletal muscle organ developmentGO:0060538780.030
reproductive processGO:0022414400.030
vasculature developmentGO:00019442780.030
signal transductionGO:00071654550.030
organic cyclic compound metabolic processGO:19013603010.030
eye developmentGO:00016542770.030
development of primary female sexual characteristicsGO:004654540.030
response to oxygen levelsGO:0070482250.030
regulation of gene expressionGO:00104682650.029
multi organism processGO:00517041340.029
respiratory system developmentGO:006054150.029
Mouse
sexual reproductionGO:0019953360.029
determination of bilateral symmetryGO:00098552040.029
pancreas developmentGO:0031016840.029
inorganic anion transportGO:0015698250.029
regulation of nucleic acid templated transcriptionGO:19035062130.028
sensory system developmentGO:0048880760.028
embryonic heart tube morphogenesisGO:00031431080.028
response to vitaminGO:003327330.028
regulation of cardiac muscle cell contractionGO:008600410.028
regulation of i kappab kinase nf kappab signalingGO:004312240.028
blood vessel morphogenesisGO:00485142160.027
response to steroid hormoneGO:0048545350.027
cell deathGO:00082191210.027
regulation of muscle contractionGO:000693730.027
ion transmembrane transportGO:0034220910.026
cellular nitrogen compound metabolic processGO:00346412900.026
central nervous system developmentGO:00074173870.025
reflexGO:006000420.025
otic vesicle morphogenesisGO:0071600340.024
cation homeostasisGO:0055080330.024
neuromuscular synaptic transmissionGO:000727420.024
cellular response to biotic stimulusGO:007121630.024
regulation of protein transportGO:005122330.024
dorsal ventral pattern formationGO:00099531250.023
ventricular system developmentGO:0021591120.023
hydrogen peroxide metabolic processGO:004274320.023
biosynthetic processGO:00090582940.023
epithelial tube morphogenesisGO:00605621480.023
response to glucoseGO:000974930.023
cellular component assemblyGO:00226071700.023
regulation of cellular biosynthetic processGO:00313262450.023
regulation of calcium ion transportGO:005192420.023
negative regulation of protein serine threonine kinase activityGO:007190120.022
heart loopingGO:0001947940.022
regionalizationGO:00030022740.022
phagocytosisGO:000690930.022
localization of cellGO:00516742440.022
response to monosaccharideGO:003428430.022
regulation of biosynthetic processGO:00098892500.022
regulation of oocyte developmentGO:006028130.022
organelle fusionGO:004828430.021
specification of symmetryGO:00097992040.021
cellular component movementGO:00069283350.021
rna metabolic processGO:00160702190.021
camera type eye developmentGO:00430102220.021
protein secretionGO:000930610.021
reproductionGO:0000003400.021
female sex differentiationGO:004666040.020
chemical homeostasisGO:0048878490.020
positive regulation of striated muscle tissue developmentGO:004584410.020
positive regulation of cellular amine metabolic processGO:003324000.020
multicellular organismal metabolic processGO:004423620.020
endodermal cell fate commitmentGO:0001711180.020
camera type eye morphogenesisGO:00485931080.020
cellular monovalent inorganic cation homeostasisGO:003000420.020
deathGO:00162651210.020
regulation of cell shapeGO:000836010.019
regulation of macromolecule metabolic processGO:00602553170.019
amine metabolic processGO:000930820.019
regulation of rna biosynthetic processGO:20011412130.019
growthGO:00400071740.019
membrane raft organizationGO:003157910.019
cellular response to steroid hormone stimulusGO:0071383310.019
cellular component morphogenesisGO:00329893360.019
regulation of multicellular organismal processGO:00512392770.019
negative regulation of kinase activityGO:003367340.019
germ cell developmentGO:0007281220.019
gene expressionGO:00104672520.019
endothelial cell differentiationGO:0045446200.019
regulation of cellular amine metabolic processGO:003323800.019
regulation of ion transmembrane transporter activityGO:003241220.018
response to virusGO:0009615210.018
regulation of protein localization to nucleusGO:190018020.018
osteoclast differentiationGO:003031610.018
oligopeptide transportGO:000685710.018
semicircular canal morphogenesisGO:0048752180.018
chloride transmembrane transportGO:190247640.018
regulation of nitrogen compound metabolic processGO:00511712510.018
collagen metabolic processGO:003296320.018
cellular response to molecule of bacterial originGO:007121930.018
lymphocyte proliferationGO:004665110.018
carbohydrate derivative metabolic processGO:1901135610.018
intracellular signal transductionGO:0035556850.018
erk1 and erk2 cascadeGO:007037140.018
central nervous system myelinationGO:002201020.018
actin filament based movementGO:003004810.017
renal system developmentGO:0072001940.017
plasma membrane repairGO:000177820.017
regulation of epithelial cell proliferationGO:005067830.017
rostrocaudal neural tube patterningGO:0021903290.017
response to arsenic containing substanceGO:004668550.017
central nervous system myelin formationGO:003228910.017
intestinal absorptionGO:005089220.017
gamete generationGO:0007276330.017
positive regulation of catabolic processGO:000989640.017
regulation of hormone secretionGO:004688320.017
behaviorGO:0007610740.017
single organism transportGO:00447652060.017
Mouse
response to external biotic stimulusGO:0043207970.016
regulation of biological qualityGO:00650082630.016
Mouse
one carbon compound transportGO:0019755140.016
inner ear developmentGO:00488391260.016
negative regulation of biological processGO:00485193040.016
limb bud formationGO:006017420.016
anatomical structure homeostasisGO:0060249360.016
ear morphogenesisGO:0042471640.016
neurotransmitter transportGO:000683620.016
p38mapk cascadeGO:003806610.016
regulation of protein targetingGO:190353320.015
retinoic acid metabolic processGO:004257390.015
regulation of neuronal synaptic plasticityGO:004816810.015
response to other organismGO:0051707970.015
multicellular organism reproductionGO:0032504350.015
cellular biosynthetic processGO:00442492860.015
response to hexoseGO:000974630.015
negative regulation of cellular processGO:00485232830.015
cardiocyte differentiationGO:0035051440.015
striated muscle cell developmentGO:00550021080.015
response to stressGO:00069502630.015
regulation of developmental processGO:00507932470.015
cellular amine metabolic processGO:004410620.015
protein heterooligomerizationGO:005129110.015
cellular response to nutrient levelsGO:003166920.015
embryonic heart tube developmentGO:00350501330.015
multicellular organism growthGO:003526440.015
glucose homeostasisGO:004259310.014
regulation of gtpase activityGO:004308720.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
regulation of cell communicationGO:00106462320.014
semicircular canal developmentGO:0060872240.014
transcription dna templatedGO:00063511810.014
regulation of cell motilityGO:2000145460.014
positive regulation of molecular functionGO:0044093330.014
intracellular receptor signaling pathwayGO:0030522300.014
apoptotic processGO:00069151160.014
hepatocyte differentiationGO:007036510.014
water homeostasisGO:003010440.014
smooth muscle contractionGO:000693920.014
actin mediated cell contractionGO:007025210.014
actin filament based processGO:0030029640.014
negative regulation of cytoplasmic transportGO:190365020.014
muscle structure developmentGO:00610611960.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
establishment of protein localization to organelleGO:007259440.014
sensory perceptionGO:0007600390.014
regulation of nucleocytoplasmic transportGO:004682220.014
tube formationGO:0035148250.013
single organism reproductive processGO:0044702400.013
cranial suture morphogenesisGO:006036310.013
phosphorus metabolic processGO:00067931090.013
gtp catabolic processGO:000618420.013
mesenchymal cell proliferationGO:001046310.013
digestive tract developmentGO:00485652650.013
multicellular organismal reproductive processGO:0048609350.013
positive regulation of cell cycleGO:004578730.013
reactive oxygen species biosynthetic processGO:190340910.013
heart developmentGO:00075073130.013
germ line stem cell divisionGO:004207810.013
regulation of wound healingGO:006104120.013
regulation of cell activationGO:005086510.013
regulation of endothelial cell proliferationGO:000193610.013
cell surface receptor signaling pathwayGO:00071663250.013
lipid storageGO:001991510.013
regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094780.013
production of molecular mediator of immune responseGO:000244020.013
head developmentGO:00603223030.012
carbohydrate homeostasisGO:003350010.012
endodermal cell fate specificationGO:0001714170.012
response to carbohydrateGO:000974330.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
response to organic cyclic compoundGO:0014070510.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
glucocorticoid biosynthetic processGO:000670410.012
cellular response to lipopolysaccharideGO:007122230.012
positive regulation of metabolic processGO:00098931080.012
embryonic digestive tract morphogenesisGO:004855730.012
multicellular organismal homeostasisGO:0048871290.012
antimicrobial humoral responseGO:001973020.012
cellular response to organic substanceGO:00713101050.012
chordate embryonic developmentGO:00430092710.012
positive regulation of epithelial cell proliferationGO:005067910.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
establishment of localization in cellGO:0051649770.012
ventricular cardiac muscle tissue morphogenesisGO:005501020.012
stem cell proliferationGO:007208940.012
response to inorganic substanceGO:0010035380.012
transcription from rna polymerase ii promoterGO:0006366800.012
positive regulation of translationGO:004572710.011
macromolecule biosynthetic processGO:00090592270.011
morphogenesis of an epithelial foldGO:006057110.011
protein stabilizationGO:005082120.011
tissue remodelingGO:004877140.011
regulation of signal transductionGO:00099662250.011
axon ensheathment in central nervous systemGO:003229120.011
sensory organ morphogenesisGO:00905962000.011
protein complex assemblyGO:0006461300.011
response to alcoholGO:0097305140.011
regulation of molecular functionGO:0065009700.011
cellular response to reactive oxygen speciesGO:003461420.011
female gamete generationGO:0007292140.011
regulation of programmed cell deathGO:00430671010.011
response to mechanical stimulusGO:0009612240.011
regulation of cellular component movementGO:0051270550.011
negative regulation of intracellular transportGO:003238730.011
regulation of membrane potentialGO:0042391230.011
cellular response to extracellular stimulusGO:003166820.011
regulation of response to external stimulusGO:0032101310.011
stem cell differentiationGO:00488631170.011
positive regulation of cell activationGO:005086710.011
regulation of signalingGO:00230512350.011
regulation of cellular ketone metabolic processGO:001056570.011
neurotransmitter secretionGO:000726920.011
nuclear transportGO:005116940.010
glomerulus vasculature developmentGO:007201220.010
hormone secretionGO:004687920.010
small molecule catabolic processGO:004428230.010
heart morphogenesisGO:00030071560.010
cellular homeostasisGO:0019725260.010
negative regulation of multi organism processGO:004390130.010
positive regulation of locomotionGO:0040017140.010
myelin assemblyGO:003228810.010
embryonic organ morphogenesisGO:00485622740.010
regulation of hydrolase activityGO:0051336280.010
detection of mechanical stimulus involved in sensory perception of soundGO:005091030.010
actin filament polymerizationGO:003004120.010
oocyte anterior posterior axis specificationGO:000731440.010

agr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.073
cardiovascular system diseaseDOID:128700.049
musculoskeletal system diseaseDOID:1700.027
artery diseaseDOID:005082800.015
vascular diseaseDOID:17800.015
bone diseaseDOID:008000100.011
bone remodeling diseaseDOID:008000500.011
connective tissue diseaseDOID:6500.011