Danio rerio

16 known processes

cd40lg

CD40 ligand

cd40lg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of production of molecular mediator of immune responseGO:000270010.155
response to other organismGO:0051707970.138
response to bacteriumGO:0009617580.130
cellular response to lipopolysaccharideGO:007122230.119
larval developmentGO:000216420.099
agingGO:000756820.095
regulation of cytokine productionGO:000181730.092
regulation of response to stimulusGO:00485832690.087
immune system processGO:00023762410.084
response to external biotic stimulusGO:0043207970.081
positive regulation of lymphocyte mediated immunityGO:000270810.080
response to biotic stimulusGO:0009607970.079
positive regulation of cytokine productionGO:000181920.079
signal transductionGO:00071654550.072
mononuclear cell proliferationGO:003294310.071
regulation of biological qualityGO:00650082630.069
regulation of protein transportGO:005122330.068
response to stressGO:00069502630.064
regulation of establishment of protein localizationGO:007020140.064
production of molecular mediator of immune responseGO:000244020.064
regulation of multicellular organismal processGO:00512392770.063
response to external stimulusGO:00096052640.062
cellular response to biotic stimulusGO:007121630.061
positive regulation of transportGO:005105020.060
cellular response to molecule of bacterial originGO:007121930.059
lipid storageGO:001991510.058
leukocyte proliferationGO:007066110.058
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.058
activation of immune responseGO:000225390.057
immunoglobulin mediated immune responseGO:001606430.054
positive regulation of biological processGO:00485182530.053
nitrogen compound metabolic processGO:00068073190.052
positive regulation of immune effector processGO:000269930.052
regulation of metabolic processGO:00192223590.048
nuclear transportGO:005116940.046
positive regulation of cell activationGO:005086710.045
regulation of multicellular organism growthGO:004001440.045
defense response to other organismGO:0098542330.045
maintenance of locationGO:005123540.044
blood vessel developmentGO:00015682460.044
defense responseGO:0006952470.043
multicellular organism growthGO:003526440.043
nucleocytoplasmic transportGO:000691340.043
regulation of gene expressionGO:00104682650.043
b cell mediated immunityGO:001972430.042
heterocycle metabolic processGO:00464832900.041
protein importGO:001703830.041
response to organic substanceGO:00100331530.039
response to chemicalGO:00422213200.039
regulation of cellular amine metabolic processGO:003323800.038
cellular macromolecule metabolic processGO:00442603910.038
b cell activationGO:004211320.038
nuclear importGO:005117030.038
humoral immune response mediated by circulating immunoglobulinGO:000245530.038
protein import into nucleusGO:000660630.037
heterocycle biosynthetic processGO:00181302150.037
regulation of primary metabolic processGO:00800903110.036
regulation of inflammatory responseGO:005072720.036
single organism nuclear importGO:190259330.036
regulation of cellular metabolic processGO:00313233200.036
cell surface receptor signaling pathwayGO:00071663250.035
lymphocyte proliferationGO:004665110.035
establishment of protein localization to organelleGO:007259440.035
regulation of nucleobase containing compound metabolic processGO:00192192500.035
nucleobase containing compound biosynthetic processGO:00346542050.035
organic substance biosynthetic processGO:19015762890.035
immune system developmentGO:00025201910.035
rna biosynthetic processGO:00327741810.034
biosynthetic processGO:00090582940.034
nucleic acid templated transcriptionGO:00976591810.033
cellular nitrogen compound metabolic processGO:00346412900.032
protein targeting to nucleusGO:004474430.032
protein localization to nucleusGO:003450430.032
toll like receptor signaling pathwayGO:000222440.032
protein secretionGO:000930610.032
positive regulation of leukocyte mediated cytotoxicityGO:000191210.032
organic cyclic compound biosynthetic processGO:19013622230.032
regulation of cell activationGO:005086510.032
immune responseGO:0006955280.032
regulation of macromolecule metabolic processGO:00602553170.032
vasculature developmentGO:00019442780.031
lymphocyte mediated immunityGO:000244950.031
transportGO:00068102200.031
protein metabolic processGO:00195381830.031
regulation of reactive oxygen species metabolic processGO:200037720.031
regulation of biosynthetic processGO:00098892500.031
regulation of cellular macromolecule biosynthetic processGO:20001122220.030
hemopoiesisGO:00300971830.030
positive regulation of cellular processGO:00485222010.030
regulation of protein localization to nucleusGO:190018020.030
blood vessel morphogenesisGO:00485142160.030
cellular amine metabolic processGO:004410620.030
positive regulation of cell cycleGO:004578730.030
response to virusGO:0009615210.030
regulation of rna metabolic processGO:00512522240.030
regulation of transcription dna templatedGO:00063552130.030
regulation of cellular biosynthetic processGO:00313262450.030
regulation of cellular amino acid metabolic processGO:000652100.029
negative regulation of biological processGO:00485193040.029
positive regulation of innate immune responseGO:004508980.029
establishment of localizationGO:00512342440.029
negative regulation of cytokine productionGO:000181810.029
regulation of signalingGO:00230512350.029
nucleic acid metabolic processGO:00903042440.029
regulation of macromolecule biosynthetic processGO:00105562250.029
cellular biosynthetic processGO:00442492860.028
transmembrane transportGO:00550851200.028
regulation of nitrogen compound metabolic processGO:00511712510.028
tube morphogenesisGO:00352393490.028
gene expressionGO:00104672520.028
symbiosis encompassing mutualism through parasitismGO:004440340.027
positive regulation of nitrogen compound metabolic processGO:0051173690.027
cellular ketone metabolic processGO:0042180110.027
positive regulation of inflammatory responseGO:005072910.027
regulation of immune responseGO:0050776140.027
positive regulation of cellular amine metabolic processGO:003324000.027
response to nutrientGO:000758430.027
positive regulation of defense responseGO:003134990.027
phosphatidylinositol mediated signalingGO:004801520.027
positive regulation of cellular amino acid metabolic processGO:004576400.026
oxoacid metabolic processGO:0043436310.026
regulation of rna biosynthetic processGO:20011412130.026
antimicrobial humoral responseGO:001973020.026
amine metabolic processGO:000930820.026
complement activationGO:000695630.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
positive regulation of secretionGO:005104710.026
organic cyclic compound metabolic processGO:19013603010.026
small molecule metabolic processGO:0044281770.026
rna metabolic processGO:00160702190.026
regulation of nucleic acid templated transcriptionGO:19035062130.025
ion transmembrane transportGO:0034220910.025
nitric oxide metabolic processGO:004620920.025
somatic muscle developmentGO:000752540.025
regulation of protein import into nucleusGO:004230620.025
inositol lipid mediated signalingGO:004801720.025
reactive nitrogen species metabolic processGO:200105700.025
type i interferon productionGO:003260620.025
multi organism processGO:00517041340.025
regulation of dna recombinationGO:000001820.025
positive regulation of leukocyte mediated immunityGO:000270510.024
regulation of cell communicationGO:00106462320.024
gastrulationGO:00073692080.024
internal protein amino acid acetylationGO:000647520.024
positive regulation of response to stimulusGO:0048584800.024
organonitrogen compound metabolic processGO:1901564740.024
homeostatic processGO:00425921420.024
stem cell maintenanceGO:001982740.024
heart developmentGO:00075073130.023
positive regulation of dna metabolic processGO:005105410.023
cellular aromatic compound metabolic processGO:00067252950.023
single organism metabolic processGO:00447102170.023
regulation of defense responseGO:0031347140.023
transcription from rna polymerase ii promoterGO:0006366800.023
cellular response to chemical stimulusGO:00708871570.023
phosphatidylinositol 3 kinase signalingGO:001406520.023
regulation of response to biotic stimulusGO:000283120.023
digestive system developmentGO:00551232890.023
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.023
cellular macromolecule biosynthetic processGO:00346452240.023
positive regulation of map kinase activityGO:004340630.023
cellular amide metabolic processGO:004360340.022
negative regulation of protein phosphorylationGO:000193340.022
peptide transportGO:001583310.022
regulation of intracellular protein transportGO:003315730.022
response to drugGO:004249330.022
single organism transportGO:00447652060.022
transcription dna templatedGO:00063511810.022
internal peptidyl lysine acetylationGO:001839320.022
female gonad developmentGO:000858540.022
positive regulation of chromatin modificationGO:190331010.022
regulation of nucleotide catabolic processGO:003081120.022
negative regulation of cellular processGO:00485232830.022
regulation of nucleocytoplasmic transportGO:004682220.022
inorganic ion transmembrane transportGO:0098660570.021
protein acetylationGO:000647320.021
cellular response to radiationGO:007147840.021
regulation of cytoplasmic transportGO:190364940.021
female sex differentiationGO:004666040.021
nucleobase containing compound metabolic processGO:00061392740.021
stem cell divisionGO:001714510.021
response to vitaminGO:003327330.021
macromolecule biosynthetic processGO:00090592270.021
leukocyte mediated cytotoxicityGO:000190910.021
regulation of protein targetingGO:190353320.021
cellular response to external stimulusGO:007149620.021
reactive oxygen species biosynthetic processGO:190340910.021
protein heterooligomerizationGO:005129110.021
positive regulation of catabolic processGO:000989640.021
response to glucocorticoidGO:005138410.021
regulation of signal transductionGO:00099662250.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
angiogenesisGO:00015251580.020
nitric oxide biosynthetic processGO:000680920.020
intracellular signal transductionGO:0035556850.020
regulation of cellular ketone metabolic processGO:001056570.020
regulation of immune system processGO:0002682340.020
embryonic organ developmentGO:00485683810.020
carboxylic acid metabolic processGO:0019752220.020
immunoglobulin productionGO:000237710.020
regulation of metal ion transportGO:001095940.020
cellular response to extracellular stimulusGO:003166820.020
cation transmembrane transportGO:0098655650.019
defense response to bacteriumGO:0042742220.019
regulation of phGO:000688530.019
cellular response to nutrient levelsGO:003166920.019
regulation of transporter activityGO:003240920.019
organic acid metabolic processGO:0006082310.019
peptidyl lysine acetylationGO:001839420.019
cellular amino acid metabolic processGO:000652070.019
central nervous system developmentGO:00074173870.019
digestive tract morphogenesisGO:00485462310.019
cellular response to organic substanceGO:00713101050.019
localization of cellGO:00516742440.019
regulation of protein ubiquitinationGO:003139630.019
stem cell proliferationGO:007208940.019
development of primary female sexual characteristicsGO:004654540.019
compound eye developmentGO:004874920.018
regulation of bindingGO:005109830.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
germ line stem cell maintenanceGO:003071820.018
positive regulation of stress activated mapk cascadeGO:003287430.018
positive regulation of secretion by cellGO:190353210.018
somatic cell dna recombinationGO:001644410.018
immune effector processGO:0002252230.018
interspecies interaction between organismsGO:004441940.018
negative regulation of immune responseGO:005077720.018
cellular component morphogenesisGO:00329893360.018
regulation of leukocyte mediated immunityGO:000270310.018
regulation of response to nutrient levelsGO:003210710.018
regulation of cellular phGO:003064110.017
positive regulation of cellular component biogenesisGO:004408930.017
positive regulation of chromosome organizationGO:200125210.017
regulation of protein catabolic processGO:004217610.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
peptide metabolic processGO:000651810.017
negative regulation of protein transportGO:005122430.017
positive regulation of myeloid cell differentiationGO:004563920.017
positive regulation of cellular catabolic processGO:003133130.017
regulation of sodium ion transportGO:000202820.017
cellular response to starvationGO:000926710.017
response to corticosteroidGO:003196010.017
aromatic compound biosynthetic processGO:00194382170.017
interferon beta productionGO:003260810.017
single organism localizationGO:19025782250.017
regulation of natural killer cell mediated immunityGO:000271510.017
positive regulation of immune system processGO:0002684170.017
adaptive immune responseGO:000225050.017
response to carbohydrateGO:000974330.017
regulation of response to cytokine stimulusGO:006075930.016
regulation of blood pressureGO:000821710.016
locomotionGO:00400113130.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
regulation of innate immune responseGO:0045088110.016
positive regulation of cell killingGO:003134320.016
positive regulation of jnk cascadeGO:004633030.016
immune response activating signal transductionGO:000275750.016
meiotic cell cycle processGO:190304630.016
cell killingGO:000190620.016
post embryonic organ developmentGO:004856940.016
negative regulation of defense responseGO:003134820.016
regulation of nucleoside metabolic processGO:000911820.016
digestive tract developmentGO:00485652650.016
regulation of blood vessel sizeGO:005088020.016
phagocytosisGO:000690930.016
regulation of apoptotic processGO:0042981980.016
regulation of protein complex assemblyGO:004325430.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
cellular carbohydrate metabolic processGO:004426240.015
regulation of tube sizeGO:003515020.015
ion transportGO:00068111140.015
cellular protein metabolic processGO:00442671290.015
specification of symmetryGO:00097992040.015
autophagyGO:000691440.015
response to hexoseGO:000974630.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
innate immune responseGO:0045087130.015
negative regulation of catabolic processGO:000989530.015
cellular component biogenesisGO:00440851780.015
glucose homeostasisGO:004259310.015
response to glucoseGO:000974930.015
positive regulation of leukocyte differentiationGO:190210710.015
response to monosaccharideGO:003428430.015
negative regulation of kinase activityGO:003367340.015
response to molecule of bacterial originGO:0002237140.015
ameboidal type cell migrationGO:00016671430.015
regulation of interferon beta productionGO:003264810.015
determination of bilateral symmetryGO:00098552040.015
cellular monovalent inorganic cation homeostasisGO:003000420.015
cellular component movementGO:00069283350.014
i kappab kinase nf kappab signalingGO:000724940.014
sensory perception of chemical stimulusGO:000760630.014
glycerol transportGO:001579370.014
negative regulation of chromosome organizationGO:200125110.014
regulation of defense response to virus by hostGO:005069110.014
modification dependent protein catabolic processGO:001994130.014
regulation of multicellular organismal developmentGO:20000262230.014
regulation of protein bindingGO:004339330.014
carbohydrate biosynthetic processGO:001605110.014
positive regulation of immune responseGO:0050778110.014
negative regulation of cellular catabolic processGO:003133030.014
regulation of purine nucleotide catabolic processGO:003312120.014
regulation of circadian rhythmGO:004275240.014
regionalizationGO:00030022740.014
cell migrationGO:00164772370.014
polyol transportGO:001579170.014
programmed cell deathGO:00125011190.014
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.014
cellular protein catabolic processGO:004425740.014
myeloid cell differentiationGO:0030099860.013
sodium ion transmembrane transportGO:0035725210.013
regulation of ion transmembrane transporter activityGO:003241220.013
regulation of response to extracellular stimulusGO:003210410.013
modification dependent macromolecule catabolic processGO:004363230.013
positive regulation of histone modificationGO:003105810.013
regulation of autophagyGO:001050630.013
regulation of cell killingGO:003134120.013
adult behaviorGO:003053420.013
morphogenesis of an epitheliumGO:00020093330.013
response to woundingGO:00096111160.013
defense response to virusGO:0051607100.013
myeloid cell homeostasisGO:0002262560.013
macroautophagyGO:001623610.013
negative regulation of dna metabolic processGO:005105340.013
cell morphogenesisGO:00009022890.013
cell substrate adhesionGO:003158940.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
response to ketoneGO:190165410.013
regulation of hormone secretionGO:004688320.013
positive regulation of translationGO:004572710.013
negative regulation of intracellular transportGO:003238730.013
regulation of striated muscle contractionGO:000694220.013
gtp metabolic processGO:004603940.013
carbohydrate homeostasisGO:003350010.013
meiotic nuclear divisionGO:000712640.013
liver developmentGO:0001889960.013
regulation of protein metabolic processGO:0051246560.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
tissue remodelingGO:004877140.013
multi organism cellular processGO:004476420.012
regulation of cellular protein metabolic processGO:0032268520.012
neuron neuron synaptic transmissionGO:000727010.012
negative regulation of protein kinase activityGO:000646940.012
protein localization to plasma membraneGO:007265910.012
ubiquitin dependent protein catabolic processGO:000651130.012
positive regulation of multicellular organismal processGO:0051240520.012
protein homooligomerizationGO:005126030.012
response to oxygen containing compoundGO:1901700550.012
regulation of muscle contractionGO:000693730.012
negative regulation of histone modificationGO:003105710.012
negative regulation of protein localization to nucleusGO:190018120.012
regulation of circadian sleep wake cycleGO:004274910.012
dorsal ventral pattern formationGO:00099531250.012
cellular response to lipidGO:0071396390.012
positive regulation of production of molecular mediator of immune responseGO:000270210.012
cell motilityGO:00488702440.012
inorganic cation transmembrane transportGO:0098662500.012
negative regulation of autophagyGO:001050710.012
erythrocyte differentiationGO:0030218540.012
determination of heart left right asymmetryGO:00613711170.012
regulation of cytokine biosynthetic processGO:004203510.012
regulation of type i interferon productionGO:003247920.012
sensory perception of painGO:001923310.012
gtp catabolic processGO:000618420.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
cell projection organizationGO:00300302840.012
response to lipidGO:0033993600.012
deathGO:00162651210.012
regulation of jak stat cascadeGO:004642530.012
regulation of growth rateGO:004000910.012
protein activation cascadeGO:007237660.012
cation transportGO:0006812810.012
pattern recognition receptor signaling pathwayGO:000222150.012
somatic stem cell maintenanceGO:003501910.012
single fertilizationGO:000733830.012
energy reserve metabolic processGO:000611220.012
response to alkaloidGO:004327920.012
urea transportGO:0015840110.012
activation of mapk activityGO:000018730.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
synaptic target recognitionGO:000803910.011
regulation of developmental processGO:00507932470.011
reactive oxygen species metabolic processGO:007259360.011
response to uvGO:000941130.011
nucleoside monophosphate catabolic processGO:000912540.011
regulation of immunoglobulin productionGO:000263710.011
hepaticobiliary system developmentGO:0061008980.011
regulation of gtpase activityGO:004308720.011
regulation of dna replicationGO:000627530.011
translational initiationGO:000641330.011
negative regulation of secretion by cellGO:190353120.011
regulation of intracellular phGO:005145310.011
epithelial cell differentiationGO:00308551160.011
lipid catabolic processGO:001604240.011
hormone secretionGO:004687920.011
regulation of cellular protein catabolic processGO:190336210.011
response to abiotic stimulusGO:00096281220.011
cellular component disassemblyGO:002241110.011
developmental growthGO:00485891660.011
pericardium developmentGO:006003910.011
negative regulation of multi organism processGO:004390130.011
response to endogenous stimulusGO:0009719830.011
negative regulation of protein import into nucleusGO:004230820.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
insulin like growth factor receptor signaling pathwayGO:004800940.011
regulation of reproductive processGO:200024140.011
regulation of organelle assemblyGO:190211540.011
phagocytosis engulfmentGO:000691110.011
dna templated transcription elongationGO:000635430.011
regulation of stem cell proliferationGO:007209120.011
atp catabolic processGO:000620040.011
toxin transportGO:190199820.011
membrane invaginationGO:001032410.011
glucose importGO:004632320.011
bmp signaling pathwayGO:0030509520.011
positive regulation of macromolecule metabolic processGO:0010604930.011
positive regulation of multi organism processGO:004390230.011
actin filament based movementGO:003004810.011
cytokinesisGO:000091030.011
viral processGO:001603210.011
inner ear developmentGO:00488391260.011
regulation of carbohydrate metabolic processGO:000610940.011
monovalent inorganic cation transportGO:0015672420.011
inorganic anion transportGO:0015698250.011
homeostasis of number of cellsGO:0048872620.011
regulation of cell deathGO:00109411030.011
regulation of cell shapeGO:000836010.011
regulation of lymphocyte mediated immunityGO:000270610.011
regulation of organ growthGO:004662030.011
chemical homeostasisGO:0048878490.011
natural killer cell mediated cytotoxicityGO:004226710.011
macromolecule modificationGO:00434121110.010
adherens junction organizationGO:003433240.010
metal ion transportGO:0030001580.010
cellular component assemblyGO:00226071700.010
positive regulation of metabolic processGO:00098931080.010
organelle organizationGO:00069962270.010
regulation of lipid transportGO:003236840.010
ion homeostasisGO:0050801410.010
single organism organelle organizationGO:19025891990.010
positive regulation of cytosolic calcium ion concentrationGO:000720440.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
camera type eye developmentGO:00430102220.010
cell cycle g1 s phase transitionGO:004484310.010
regulation of molecular functionGO:0065009700.010
positive regulation of gliogenesisGO:001401520.010
heart processGO:0003015710.010
regulation of defense response to virusGO:005068820.010
circulatory system processGO:0003013870.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
ribonucleoside monophosphate catabolic processGO:000915840.010
regulation of leukocyte mediated cytotoxicityGO:000191010.010
retinal rod cell developmentGO:004654840.010
negative regulation of response to stimulusGO:00485851040.010
system processGO:00030081850.010
photoreceptor cell fate commitmentGO:004655210.010
negative regulation of secretionGO:005104820.010

cd40lg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.023
musculoskeletal system diseaseDOID:1700.018
inherited metabolic disorderDOID:65500.017
disease of metabolismDOID:001466700.017
eye and adnexa diseaseDOID:149200.015
sensory system diseaseDOID:005015500.015
eye diseaseDOID:561400.013
organ system cancerDOID:005068600.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011