Danio rerio

8 known processes

sema6e

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E

(Aliases: bZ1N7.1,si:rp71-1n7.1)

sema6e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.093
larval developmentGO:000216420.083
Zebrafish
sensory organ developmentGO:00074233930.078
central nervous system developmentGO:00074173870.076
Zebrafish Fly
rna metabolic processGO:00160702190.071
cellular macromolecule metabolic processGO:00442603910.057
nitrogen compound metabolic processGO:00068073190.052
organic cyclic compound metabolic processGO:19013603010.051
cellular nitrogen compound metabolic processGO:00346412900.049
negative regulation of biological processGO:00485193040.046
regulation of metabolic processGO:00192223590.046
cellular aromatic compound metabolic processGO:00067252950.046
generation of neuronsGO:00486993850.044
Zebrafish Rat Fly
biosynthetic processGO:00090582940.044
gene expressionGO:00104672520.044
regulation of nitrogen compound metabolic processGO:00511712510.044
heterocycle metabolic processGO:00464832900.043
cellular biosynthetic processGO:00442492860.043
cellular macromolecule biosynthetic processGO:00346452240.043
regulation of biological qualityGO:00650082630.043
Zebrafish Fly
regulation of biosynthetic processGO:00098892500.042
heart developmentGO:00075073130.041
Zebrafish
macromolecule biosynthetic processGO:00090592270.041
nucleobase containing compound metabolic processGO:00061392740.040
regulation of cell shapeGO:000836010.039
organic substance biosynthetic processGO:19015762890.039
amine metabolic processGO:000930820.038
nucleic acid templated transcriptionGO:00976591810.038
chordate embryonic developmentGO:00430092710.038
Zebrafish
morphogenesis of an epitheliumGO:00020093330.038
Zebrafish
cellular response to external stimulusGO:007149620.037
leukocyte proliferationGO:007066110.037
regulation of macromolecule biosynthetic processGO:00105562250.037
multicellular organism growthGO:003526440.037
nucleic acid metabolic processGO:00903042440.037
vasculature developmentGO:00019442780.036
Zebrafish
response to stressGO:00069502630.036
Zebrafish
organic cyclic compound biosynthetic processGO:19013622230.036
positive regulation of cellular catabolic processGO:003133130.035
regulation of transcription dna templatedGO:00063552130.035
embryonic organ developmentGO:00485683810.035
Zebrafish
regulation of primary metabolic processGO:00800903110.035
positive regulation of catabolic processGO:000989640.035
embryonic organ morphogenesisGO:00485622740.035
Zebrafish
head developmentGO:00603223030.034
Zebrafish Fly
positive regulation of transportGO:005105020.034
eye developmentGO:00016542770.034
regulation of gene expressionGO:00104682650.033
regulation of rna metabolic processGO:00512522240.033
nucleobase containing compound biosynthetic processGO:00346542050.033
aromatic compound biosynthetic processGO:00194382170.032
tube morphogenesisGO:00352393490.032
Zebrafish
blood vessel developmentGO:00015682460.032
Zebrafish
adult behaviorGO:003053420.031
system processGO:00030081850.031
Fly
sensory organ morphogenesisGO:00905962000.031
protein localization to nucleusGO:003450430.031
regulation of cellular metabolic processGO:00313233200.031
protein importGO:001703830.030
establishment of protein localization to organelleGO:007259440.030
regulation of cellular biosynthetic processGO:00313262450.029
heterocycle biosynthetic processGO:00181302150.029
transcription from rna polymerase ii promoterGO:0006366800.029
regulation of macromolecule metabolic processGO:00602553170.029
oxoacid metabolic processGO:0043436310.029
protein targeting to nucleusGO:004474430.028
rna biosynthetic processGO:00327741810.028
regulation of cellular amino acid metabolic processGO:000652100.028
blood vessel morphogenesisGO:00485142160.028
Zebrafish
regulation of developmental processGO:00507932470.028
Zebrafish Fly
negative regulation of cellular processGO:00485232830.027
regulation of multicellular organism growthGO:004001440.027
single organism nuclear importGO:190259330.027
cell morphogenesisGO:00009022890.027
Zebrafish Rat Fly
phagocytosisGO:000690930.026
cellular component movementGO:00069283350.026
Zebrafish Rat Fly
eye morphogenesisGO:00485921440.026
cellular amino acid metabolic processGO:000652070.026
transcription dna templatedGO:00063511810.026
regulation of nucleobase containing compound metabolic processGO:00192192500.025
cell motilityGO:00488702440.025
Zebrafish
regulation of protein catabolic processGO:004217610.025
maintenance of locationGO:005123540.025
regulation of nucleic acid templated transcriptionGO:19035062130.025
regionalizationGO:00030022740.025
modification dependent protein catabolic processGO:001994130.025
cellular amine metabolic processGO:004410620.025
organonitrogen compound metabolic processGO:1901564740.024
cellular ketone metabolic processGO:0042180110.024
small molecule metabolic processGO:0044281770.024
protein import into nucleusGO:000660630.024
regulation of rna biosynthetic processGO:20011412130.023
signal transductionGO:00071654550.023
Fly
heart morphogenesisGO:00030071560.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.023
regulation of cellular amine metabolic processGO:003323800.023
meiotic nuclear divisionGO:000712640.023
single organism metabolic processGO:00447102170.022
nuclear transportGO:005116940.022
response to drugGO:004249330.022
lipid storageGO:001991510.022
regulation of cytoplasmic transportGO:190364940.022
organic acid metabolic processGO:0006082310.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
phagocytosis engulfmentGO:000691110.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
cellular component morphogenesisGO:00329893360.022
Zebrafish Rat Fly
nuclear importGO:005117030.021
cell surface receptor signaling pathwayGO:00071663250.021
Fly
astrocyte differentiationGO:004870810.021
cell projection organizationGO:00300302840.021
Zebrafish Rat Fly
regulation of multicellular organismal developmentGO:20000262230.021
Zebrafish Fly
regulation of intracellular protein transportGO:003315730.021
regulation of protein transportGO:005122330.021
regulation of establishment of protein localizationGO:007020140.021
regulation of protein targetingGO:190353320.021
cellular protein catabolic processGO:004425740.021
retina development in camera type eyeGO:00600411460.021
positive regulation of biological processGO:00485182530.021
mononuclear cell proliferationGO:003294310.021
regulation of cellular ketone metabolic processGO:001056570.020
muscle structure developmentGO:00610611960.020
extrinsic apoptotic signaling pathwayGO:009719130.020
regulation of bindingGO:005109830.020
regulation of metal ion transportGO:001095940.020
cellular lipid catabolic processGO:004424230.020
neuron differentiationGO:00301823530.020
Zebrafish Rat Fly
glial cell migrationGO:000834730.020
locomotionGO:00400113130.019
positive regulation of cell cycleGO:004578730.019
positive regulation of blood circulationGO:190352420.019
regulation of dendrite developmentGO:005077330.019
cellular response to extracellular stimulusGO:003166820.019
embryo development ending in birth or egg hatchingGO:00097922710.019
Zebrafish Fly
nuclear migrationGO:000709730.019
neuron projection developmentGO:00311751800.019
Zebrafish Rat Fly
positive regulation of purine nucleotide catabolic processGO:003312310.019
negative regulation of protein phosphorylationGO:000193340.019
cranial nerve developmentGO:0021545420.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
regulation of reproductive processGO:200024140.019
regulation of protein localization to nucleusGO:190018020.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
skeletal system developmentGO:00015011810.019
Zebrafish
proteolysis involved in cellular protein catabolic processGO:005160330.019
positive regulation of metabolic processGO:00098931080.019
positive regulation of cellular processGO:00485222010.019
stem cell maintenanceGO:001982740.018
mitochondrion organizationGO:000700540.018
gtp catabolic processGO:000618420.018
nucleocytoplasmic transportGO:000691340.018
regulation of cytokine productionGO:000181730.018
modification dependent macromolecule catabolic processGO:004363230.018
response to hexoseGO:000974630.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
digestive system developmentGO:00551232890.018
positive regulation of nucleoside metabolic processGO:004597910.018
regulation of blood pressureGO:000821710.018
regulation of mrna processingGO:005068430.018
regulation of protein import into nucleusGO:004230620.017
multicellular organismal signalingGO:0035637220.017
transportGO:00068102200.017
positive regulation of cellular component biogenesisGO:004408930.017
guanosine containing compound metabolic processGO:190106840.017
camera type eye developmentGO:00430102220.017
single organism transportGO:00447652060.017
positive regulation of nucleotide catabolic processGO:003081310.017
growthGO:00400071740.017
Zebrafish
ribonucleoside monophosphate catabolic processGO:000915840.017
anterior posterior pattern specificationGO:00099521520.017
mesenchyme developmentGO:00604851270.017
Zebrafish
immune system processGO:00023762410.017
Zebrafish
response to chemicalGO:00422213200.017
regulation of erk1 and erk2 cascadeGO:007037240.017
skeletal system morphogenesisGO:00487051020.017
Zebrafish
gtp metabolic processGO:004603940.017
regulation of multicellular organismal processGO:00512392770.017
Zebrafish Fly
brain developmentGO:00074202930.017
Zebrafish Fly
localization of cellGO:00516742440.017
Zebrafish
regulation of cell activationGO:005086510.016
carboxylic acid metabolic processGO:0019752220.016
pigmentationGO:0043473850.016
membrane fusionGO:006102520.016
regulation of signal transductionGO:00099662250.016
positive regulation of cellular amine metabolic processGO:003324000.016
positive regulation of nucleobase containing compound metabolic processGO:0045935690.016
compound eye developmentGO:004874920.016
nucleoside monophosphate catabolic processGO:000912540.016
regulation of filopodium assemblyGO:005148920.016
response to external stimulusGO:00096052640.016
regulation of cell communicationGO:00106462320.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
regulation of glial cell differentiationGO:004568540.016
carbon dioxide transportGO:001567030.016
proteasomal protein catabolic processGO:001049820.016
regulation of cell projection assemblyGO:006049140.015
female gonad developmentGO:000858540.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
fatty acid transportGO:001590810.015
ubiquitin dependent protein catabolic processGO:000651130.015
somatic muscle developmentGO:000752540.015
ear developmentGO:00435831270.015
specification of symmetryGO:00097992040.015
lens development in camera type eyeGO:0002088220.015
protein metabolic processGO:00195381830.015
regulation of nucleotide catabolic processGO:003081120.015
protein localization to plasma membraneGO:007265910.015
guanosine containing compound catabolic processGO:190106920.015
cellular component disassemblyGO:002241110.015
regulation of reactive oxygen species metabolic processGO:200037720.015
single organism organelle organizationGO:19025891990.015
organelle assemblyGO:00709251100.015
sleepGO:003043110.015
epithelial tube morphogenesisGO:00605621480.015
Zebrafish
positive regulation of gtp catabolic processGO:003312610.015
response to organic substanceGO:00100331530.015
organelle organizationGO:00069962270.015
cell projection morphogenesisGO:00488582440.015
Zebrafish Rat Fly
cellular carbohydrate metabolic processGO:004426240.015
cell deathGO:00082191210.015
membrane invaginationGO:001032410.014
cellular component assemblyGO:00226071700.014
Fly
response to alkaloidGO:004327920.014
stem cell proliferationGO:007208940.014
inner ear developmentGO:00488391260.014
stem cell differentiationGO:00488631170.014
Zebrafish
regulation of cell substrate adhesionGO:001081010.014
neuron developmentGO:00486662620.014
Zebrafish Rat Fly
atp catabolic processGO:000620040.014
adherens junction organizationGO:003433240.014
interspecies interaction between organismsGO:004441940.014
regulation of response to stimulusGO:00485832690.014
Fly
regulation of transmembrane transporter activityGO:002289820.014
single organism localizationGO:19025782250.014
cellular response to nutrient levelsGO:003166920.014
determination of heart left right asymmetryGO:00613711170.014
cell morphogenesis involved in differentiationGO:00009041950.014
Zebrafish Rat Fly
regulation of gtp catabolic processGO:003312420.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
cilium organizationGO:0044782710.014
regulation of protein complex assemblyGO:004325430.014
regulation of nucleocytoplasmic transportGO:004682220.014
urogenital system developmentGO:0001655970.014
positive regulation of cell adhesionGO:004578510.014
actin polymerization or depolymerizationGO:000815420.014
regulation of sodium ion transportGO:000202820.013
positive regulation of gtpase activityGO:004354710.013
cellular response to starvationGO:000926710.013
camera type eye morphogenesisGO:00485931080.013
kidney developmentGO:0001822920.013
mesenchymal cell differentiationGO:0048762870.013
Zebrafish
cell migrationGO:00164772370.013
Zebrafish
cell substrate adhesionGO:003158940.013
response to carbohydrateGO:000974330.013
establishment of localizationGO:00512342440.013
action potentialGO:0001508190.013
nerve developmentGO:0021675450.013
cellular response to oxygen levelsGO:007145310.013
embryonic skeletal system developmentGO:0048706970.013
Zebrafish
lymphocyte proliferationGO:004665110.013
meiotic cell cycle processGO:190304630.013
regenerationGO:0031099910.013
Zebrafish
synaptic growth at neuromuscular junctionGO:005112420.013
negative regulation of protein kinase activityGO:000646940.013
meiosis iGO:000712710.013
positive regulation of cytokine productionGO:000181920.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
fertilizationGO:000956630.013
homeostatic processGO:00425921420.013
regulation of purine nucleotide catabolic processGO:003312120.013
hemopoiesisGO:00300971830.013
dorsal ventral pattern formationGO:00099531250.013
convergent extensionGO:00600261180.013
secondary metabolic processGO:001974830.013
cellular amide metabolic processGO:004360340.013
muscle tissue developmentGO:00605371100.013
negative regulation of map kinase activityGO:004340720.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
protein homooligomerizationGO:005126030.013
regulation of ion transmembrane transporter activityGO:003241220.013
developmental programmed cell deathGO:001062340.013
cell projection assemblyGO:0030031640.013
digestive tract developmentGO:00485652650.013
cell matrix adhesionGO:000716040.013
striated muscle tissue developmentGO:00147061100.012
neural crest cell developmentGO:0014032620.012
Zebrafish
regulation of i kappab kinase nf kappab signalingGO:004312240.012
chemosensory behaviorGO:000763510.012
positive regulation of secretionGO:005104710.012
cognitionGO:005089010.012
embryonic skeletal system morphogenesisGO:0048704930.012
Zebrafish
production of molecular mediator of immune responseGO:000244020.012
deathGO:00162651210.012
circulatory system processGO:0003013870.012
determination of bilateral symmetryGO:00098552040.012
multicellular organismal metabolic processGO:004423620.012
embryonic heart tube developmentGO:00350501330.012
Zebrafish
response to organic cyclic compoundGO:0014070510.012
cellular protein metabolic processGO:00442671290.012
angiogenesisGO:00015251580.012
Zebrafish
regulation of synaptic plasticityGO:004816710.012
developmental growthGO:00485891660.012
Zebrafish
ventricular cardiac muscle tissue developmentGO:000322930.012
cell cycle g1 s phase transitionGO:004484310.012
female sex differentiationGO:004666040.012
g1 s transition of mitotic cell cycleGO:000008210.012
energy reserve metabolic processGO:000611220.012
blood circulationGO:0008015870.012
epithelial cell differentiationGO:00308551160.012
myeloid cell differentiationGO:0030099860.012
digestive tract morphogenesisGO:00485462310.012
startle responseGO:000196440.012
Fly
regulation of inflammatory responseGO:005072720.012
positive regulation of biosynthetic processGO:0009891680.012
single fertilizationGO:000733830.012
meiotic chromosome segregationGO:004513230.012
protein secretionGO:000930610.012
cell part morphogenesisGO:00329902460.012
Zebrafish Rat Fly
positive regulation of map kinase activityGO:004340630.012
reactive oxygen species biosynthetic processGO:190340910.012
regulation of protein ubiquitinationGO:003139630.012
apoptotic processGO:00069151160.012
axon ensheathment in central nervous systemGO:003229120.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
Zebrafish
regulation of nucleoside metabolic processGO:000911820.012
positive regulation of cytoskeleton organizationGO:005149530.012
regulation of gtpase activityGO:004308720.012
muscle cell differentiationGO:00426921390.011
hypothalamus cell differentiationGO:002197940.011
response to glucoseGO:000974930.011
regulation of production of molecular mediator of immune responseGO:000270010.011
b cell activationGO:004211320.011
central nervous system myelinationGO:002201020.011
negative regulation of signal transductionGO:0009968940.011
positive regulation of muscle tissue developmentGO:190186310.011
response to nutrientGO:000758430.011
positive regulation of cellular metabolic processGO:0031325940.011
regulation of muscle contractionGO:000693730.011
regulation of tube sizeGO:003515020.011
exocytosisGO:000688710.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
regulation of organ growthGO:004662030.011
long chain fatty acid metabolic processGO:000167610.011
nitric oxide metabolic processGO:004620920.011
peptidyl serine phosphorylationGO:001810510.011
embryonic heart tube morphogenesisGO:00031431080.011
hindbrain developmentGO:0030902910.011
Zebrafish
regulation of protein bindingGO:004339330.011
inner ear morphogenesisGO:0042472630.011
mesenchymal cell developmentGO:0014031780.011
Zebrafish
macromolecule modificationGO:00434121110.011
centrosome organizationGO:005129710.011
gland developmentGO:00487321430.011
Zebrafish
regulation of protein modification by small protein conjugation or removalGO:190332030.011
regulation of cellular protein catabolic processGO:190336210.011
olfactory bulb developmentGO:002177240.011
cellular response to radiationGO:007147840.011
regulation of anatomical structure morphogenesisGO:00226031300.011
Zebrafish Fly
regulation of membrane potentialGO:0042391230.011
negative regulation of signalingGO:0023057960.011
negative regulation of kinase activityGO:003367340.011
heart loopingGO:0001947940.010
regulation of dendrite morphogenesisGO:004881430.010
single organism membrane fusionGO:004480120.010
immune system developmentGO:00025201910.010
Zebrafish
phosphatidylinositol 3 kinase signalingGO:001406520.010
regulation of signalingGO:00230512350.010
transmission of nerve impulseGO:0019226190.010
regulation of cell differentiationGO:00455951420.010
Zebrafish Fly
purine nucleoside monophosphate catabolic processGO:000912840.010
embryonic cranial skeleton morphogenesisGO:0048701900.010
positive regulation of macromolecule metabolic processGO:0010604930.010
positive regulation of cell divisionGO:005178120.010
erk1 and erk2 cascadeGO:007037140.010
muscle cell developmentGO:00550011150.010
neuronal action potentialGO:0019228180.010
cellular component assembly involved in morphogenesisGO:00109271070.010
skeletal muscle organ developmentGO:0060538780.010
regulation of epithelial cell proliferationGO:005067830.010
positive regulation of macromolecule biosynthetic processGO:0010557590.010
cellular protein modification processGO:00064641000.010
response to monosaccharideGO:003428430.010
regulation of response to biotic stimulusGO:000283120.010
regulation of transporter activityGO:003240920.010
cytokinesisGO:000091030.010
renal system developmentGO:0072001940.010
regulation of protein polymerizationGO:003227120.010
positive regulation of immune effector processGO:000269930.010

sema6e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
cardiovascular system diseaseDOID:128700.030
musculoskeletal system diseaseDOID:1700.024
connective tissue diseaseDOID:6500.021
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
organ system cancerDOID:005068600.018
muscular diseaseDOID:008000000.013
bone diseaseDOID:008000100.013
nervous system diseaseDOID:86300.013
muscle tissue diseaseDOID:6600.011
disease of metabolismDOID:001466700.011
myopathyDOID:42300.010