Danio rerio

0 known processes

wipi2

WD repeat domain, phosphoinositide interacting 2

(Aliases: zgc:92576)

wipi2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.274
cellular macromolecule metabolic processGO:00442603910.168
modification dependent protein catabolic processGO:001994130.132
morphogenesis of an epitheliumGO:00020093330.131
single organism metabolic processGO:00447102170.119
agingGO:000756820.098
modification dependent macromolecule catabolic processGO:004363230.096
cellular component assemblyGO:00226071700.095
meiotic nuclear divisionGO:000712640.087
regulation of cellular ketone metabolic processGO:001056570.078
autophagyGO:000691440.074
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.063
response to stressGO:00069502630.061
cellular ketone metabolic processGO:0042180110.060
regulation of primary metabolic processGO:00800903110.059
regulation of biosynthetic processGO:00098892500.057
cellular response to external stimulusGO:007149620.055
proteolysis involved in cellular protein catabolic processGO:005160330.054
establishment of protein localization to organelleGO:007259440.051
ubiquitin dependent protein catabolic processGO:000651130.050
cellular response to nutrient levelsGO:003166920.050
cellular aromatic compound metabolic processGO:00067252950.047
negative regulation of biological processGO:00485193040.046
cellular response to starvationGO:000926710.046
central nervous system developmentGO:00074173870.046
cellular response to extracellular stimulusGO:003166820.045
nitrogen compound metabolic processGO:00068073190.045
macroautophagyGO:001623610.044
cellular protein catabolic processGO:004425740.044
regulation of cellular metabolic processGO:00313233200.044
guanosine containing compound metabolic processGO:190106840.043
maintenance of locationGO:005123540.042
phagocytosisGO:000690930.042
organelle organizationGO:00069962270.041
proteasomal protein catabolic processGO:001049820.041
cellular component biogenesisGO:00440851780.041
response to uvGO:000941130.041
lateral inhibitionGO:004633110.040
digestive tract morphogenesisGO:00485462310.039
regulation of meiotic cell cycleGO:005144510.039
protein metabolic processGO:00195381830.039
cellular carbohydrate metabolic processGO:004426240.039
cellular protein metabolic processGO:00442671290.038
protein importGO:001703830.037
regulation of nitrogen compound metabolic processGO:00511712510.037
meiotic cell cycle processGO:190304630.036
sister chromatid cohesionGO:000706220.035
negative regulation of cellular processGO:00485232830.035
multicellular organism growthGO:003526440.035
lipid storageGO:001991510.034
negative regulation of protein phosphorylationGO:000193340.034
cellular catabolic processGO:0044248270.034
positive regulation of transportGO:005105020.034
signal transductionGO:00071654550.033
positive regulation of catabolic processGO:000989640.033
cellular protein modification processGO:00064641000.032
response to biotic stimulusGO:0009607970.032
localization within membraneGO:005166810.032
cell surface receptor signaling pathwayGO:00071663250.031
post embryonic organ developmentGO:004856940.031
regulation of multicellular organism growthGO:004001440.031
dna templated transcription elongationGO:000635430.031
convergent extensionGO:00600261180.031
regulation of carbohydrate metabolic processGO:000610940.031
cellular component morphogenesisGO:00329893360.030
embryonic organ developmentGO:00485683810.029
regulation of protein targetingGO:190353320.029
regulation of epithelial cell proliferationGO:005067830.029
response to organic substanceGO:00100331530.028
determination of left right symmetryGO:00073681790.028
wnt signaling pathwayGO:0016055800.028
regulation of stem cell proliferationGO:007209120.028
digestive system developmentGO:00551232890.028
g2 dna damage checkpointGO:003157230.028
response to topologically incorrect proteinGO:003596620.028
odontogenesis of dentin containing toothGO:004247510.027
organic acid metabolic processGO:0006082310.027
female sex differentiationGO:004666040.027
regulation of nucleocytoplasmic transportGO:004682220.027
cellular amine metabolic processGO:004410620.027
golgi vesicle transportGO:004819330.026
regulation of biological qualityGO:00650082630.026
regulation of protein localization to nucleusGO:190018020.026
stem cell divisionGO:001714510.026
meiosis iGO:000712710.026
heart morphogenesisGO:00030071560.026
tissue remodelingGO:004877140.026
determination of bilateral symmetryGO:00098552040.025
regulation of rna metabolic processGO:00512522240.025
macromolecule modificationGO:00434121110.025
cell substrate adhesionGO:003158940.025
protein k48 linked ubiquitinationGO:007093610.025
liver developmentGO:0001889960.025
organelle assemblyGO:00709251100.025
single organism biosynthetic processGO:0044711710.024
tube morphogenesisGO:00352393490.024
regulation of cell shapeGO:000836010.024
organic cyclic compound metabolic processGO:19013603010.024
small molecule metabolic processGO:0044281770.024
adult behaviorGO:003053420.024
meiotic chromosome segregationGO:004513230.024
cellular response to radiationGO:007147840.024
cell projection morphogenesisGO:00488582440.024
localization of cellGO:00516742440.024
regulation of peptidyl tyrosine phosphorylationGO:005073010.024
nuclear importGO:005117030.024
cytokinesisGO:000091030.024
cellular response to light stimulusGO:007148240.023
cell motilityGO:00488702440.023
regulation of tube sizeGO:003515020.023
cell migrationGO:00164772370.023
response to virusGO:0009615210.023
oxoacid metabolic processGO:0043436310.023
positive regulation of stem cell proliferationGO:200064810.023
heterocycle metabolic processGO:00464832900.023
cellular component movementGO:00069283350.023
positive regulation of cell cycleGO:004578730.023
er to golgi vesicle mediated transportGO:000688810.023
single organism nuclear importGO:190259330.023
transcription elongation from rna polymerase ii promoterGO:000636830.022
regulation of cellular amino acid metabolic processGO:000652100.022
heart loopingGO:0001947940.022
protein localization to nucleusGO:003450430.022
cell projection organizationGO:00300302840.022
gastrulationGO:00073692080.022
lipid homeostasisGO:005508830.022
positive regulation of canonical wnt signaling pathwayGO:009026340.022
regulation of response to biotic stimulusGO:000283120.022
gtp catabolic processGO:000618420.021
regulation of developmental processGO:00507932470.021
embryonic heart tube morphogenesisGO:00031431080.021
response to vitaminGO:003327330.021
cellular amino acid metabolic processGO:000652070.021
gtp metabolic processGO:004603940.021
positive regulation of mesenchymal cell proliferationGO:000205310.021
chromosome organization involved in meiosisGO:007019210.021
mitochondrion organizationGO:000700540.021
digestive tract developmentGO:00485652650.021
regulation of protein catabolic processGO:004217610.021
neurotransmitter transportGO:000683620.020
carbohydrate biosynthetic processGO:001605110.020
cellular nitrogen compound metabolic processGO:00346412900.020
regulation of neuronal synaptic plasticityGO:004816810.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
negative regulation of epithelial cell proliferationGO:005068010.020
cellular biosynthetic processGO:00442492860.020
brain developmentGO:00074202930.020
amine metabolic processGO:000930820.020
specification of symmetryGO:00097992040.020
protein import into nucleusGO:000660630.019
primary neural tube formationGO:001402010.019
single organism organelle organizationGO:19025891990.019
response to chemicalGO:00422213200.019
stem cell proliferationGO:007208940.019
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.019
response to external stimulusGO:00096052640.019
developmental growthGO:00485891660.019
regulation of cellular biosynthetic processGO:00313262450.019
microtubule cytoskeleton organization involved in mitosisGO:190285010.019
cellular response to chemical stimulusGO:00708871570.019
protein modification processGO:00362111000.018
mitotic sister chromatid segregationGO:000007060.018
regulation of fatty acid metabolic processGO:001921710.018
regulation of organ growthGO:004662030.018
embryonic organ morphogenesisGO:00485622740.018
double strand break repair via homologous recombinationGO:000072410.018
regulation of jak stat cascadeGO:004642530.018
regulation of blood vessel sizeGO:005088020.018
vacuolar transportGO:000703420.018
lipid metabolic processGO:0006629520.018
regulation of transcription dna templatedGO:00063552130.018
nucleobase containing compound metabolic processGO:00061392740.018
cell morphogenesisGO:00009022890.017
protein polyubiquitinationGO:000020940.017
organic cyclic compound biosynthetic processGO:19013622230.017
regulation of synaptic plasticityGO:004816710.017
secondary metabolic processGO:001974830.017
phosphate containing compound metabolic processGO:00067961080.017
g1 s transition of mitotic cell cycleGO:000008210.017
neuron differentiationGO:00301823530.017
cell matrix adhesionGO:000716040.017
protein acylationGO:004354330.017
nucleocytoplasmic transportGO:000691340.017
regulation of protein import into nucleusGO:004230620.017
regulation of establishment of protein localizationGO:007020140.017
camera type eye developmentGO:00430102220.017
cell cycle g1 s phase transitionGO:004484310.017
catabolic processGO:0009056320.017
nucleobase containing compound biosynthetic processGO:00346542050.016
rna metabolic processGO:00160702190.016
response to nutrientGO:000758430.016
regulation of production of molecular mediator of immune responseGO:000270010.016
protein targeting to nucleusGO:004474430.016
neurotransmitter secretionGO:000726920.016
alcohol biosynthetic processGO:004616520.016
regulation of signalingGO:00230512350.016
regulation of reproductive processGO:200024140.016
organonitrogen compound metabolic processGO:1901564740.016
cell part morphogenesisGO:00329902460.016
regulation of protein transportGO:005122330.016
growthGO:00400071740.016
protein homooligomerizationGO:005126030.016
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.016
protein modification by small protein removalGO:007064610.016
gene expressionGO:00104672520.016
positive regulation of erk1 and erk2 cascadeGO:007037420.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
head developmentGO:00603223030.016
phosphatidylinositol 3 kinase signalingGO:001406520.016
regulation of intracellular protein transportGO:003315730.016
embryo development ending in birth or egg hatchingGO:00097922710.016
tube closureGO:006060610.015
positive regulation of biological processGO:00485182530.015
defense response to virusGO:0051607100.015
synaptic growth at neuromuscular junctionGO:005112420.015
regulation of bindingGO:005109830.015
cellular response to oxygen levelsGO:007145310.015
regulation of protein bindingGO:004339330.015
stem cell maintenanceGO:001982740.015
muscle cell differentiationGO:00426921390.015
regulation of cytoplasmic transportGO:190364940.015
single organism localizationGO:19025782250.015
circulatory system processGO:0003013870.015
cellular response to stressGO:0033554620.015
triglyceride homeostasisGO:007032820.015
regulation of neural precursor cell proliferationGO:200017730.015
developmental growth involved in morphogenesisGO:0060560860.015
regulation of metabolic processGO:00192223590.015
germ line stem cell maintenanceGO:003071820.015
peptidyl lysine acetylationGO:001839420.015
cellular lipid metabolic processGO:0044255360.015
response to nicotineGO:003509420.015
inositol lipid mediated signalingGO:004801720.014
guanosine containing compound catabolic processGO:190106920.014
regulation of mesenchymal cell proliferationGO:001046410.014
acylglycerol homeostasisGO:005509020.014
macromolecule biosynthetic processGO:00090592270.014
heart developmentGO:00075073130.014
monocarboxylic acid catabolic processGO:007232930.014
female gonad developmentGO:000858540.014
regulation of dna recombinationGO:000001820.014
negative regulation of metabolic processGO:0009892860.014
regulation of stem cell differentiationGO:200073640.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
regulation of synapse organizationGO:005080730.014
heart contractionGO:0060047710.014
membrane invaginationGO:001032410.014
negative regulation of kinase activityGO:003367340.014
protein heterooligomerizationGO:005129110.014
nuclear transportGO:005116940.014
phosphatidylinositol mediated signalingGO:004801520.014
cell agingGO:000756920.014
development of primary female sexual characteristicsGO:004654540.013
endoplasmic reticulum unfolded protein responseGO:003096820.013
positive regulation of cellular catabolic processGO:003133130.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
positive regulation of blood circulationGO:190352420.013
regulation of cell communicationGO:00106462320.013
macromolecular complex subunit organizationGO:0043933740.013
positive regulation of chromosome organizationGO:200125210.013
intracellular mrna localizationGO:000829810.013
proteolysisGO:0006508380.013
regulation of cellular amine metabolic processGO:003323800.013
neuron developmentGO:00486662620.013
positive regulation of cellular amine metabolic processGO:003324000.013
negative regulation of protein kinase activityGO:000646940.013
lipid oxidationGO:003444010.013
i kappab kinase nf kappab signalingGO:000724940.013
positive regulation of secretionGO:005104710.013
response to unfolded proteinGO:000698620.013
regulation of neurotransmitter secretionGO:004692810.013
response to alkaloidGO:004327920.013
ameboidal type cell migrationGO:00016671430.013
regulation of cellular response to growth factor stimulusGO:0090287350.013
mesenchymal cell proliferationGO:001046310.013
defense responseGO:0006952470.013
phosphorus metabolic processGO:00067931090.013
organic acid catabolic processGO:001605430.013
alternative mrna splicing via spliceosomeGO:000038010.013
response to drugGO:004249330.012
fatty acid catabolic processGO:000906210.012
mitotic g2 dna damage checkpointGO:000709530.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
regulation of erk1 and erk2 cascadeGO:007037240.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
regulation of signal transductionGO:00099662250.012
regulation of bone mineralizationGO:003050020.012
rna localizationGO:000640340.012
multicellular organismal metabolic processGO:004423620.012
cartilage developmentGO:0051216960.012
establishment of epithelial cell polarityGO:009016220.012
regulation of gene expressionGO:00104682650.012
embryonic skeletal joint developmentGO:007249830.012
cellular response to organic substanceGO:00713101050.012
neuromuscular process controlling balanceGO:005088530.012
positive regulation of cellular component biogenesisGO:004408930.012
endosome to lysosome transportGO:000833310.012
recombinational repairGO:000072510.012
negative regulation of stem cell differentiationGO:200073720.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
regulation of metal ion transportGO:001095940.012
somatic stem cell maintenanceGO:003501910.012
dorsal ventral pattern formationGO:00099531250.012
embryonic hemopoiesisGO:0035162530.012
regulation of mrna splicing via spliceosomeGO:004802430.012
regulation of mrna processingGO:005068430.012
negative regulation of defense responseGO:003134820.012
protein acetylationGO:000647320.012
establishment of localization in cellGO:0051649770.012
germ line stem cell divisionGO:004207810.011
double strand break repairGO:000630230.011
regulation of dendrite developmentGO:005077330.011
phagosome maturationGO:009038210.011
cytoplasm organizationGO:000702840.011
gland developmentGO:00487321430.011
carboxylic acid metabolic processGO:0019752220.011
cellular response to hypoxiaGO:007145610.011
organelle localizationGO:0051640490.011
mitotic nuclear divisionGO:0007067180.011
spindle assemblyGO:005122520.011
blood circulationGO:0008015870.011
positive regulation of cell divisionGO:005178120.011
fin developmentGO:0033333770.011
mitotic cell cycleGO:0000278640.011
organic substance biosynthetic processGO:19015762890.011
hepaticobiliary system developmentGO:0061008980.011
regulation of response to cytokine stimulusGO:006075930.011
positive regulation of dna metabolic processGO:005105410.011
neuronal stem cell maintenanceGO:009715020.011
protein modification by small protein conjugation or removalGO:0070647140.011
centrosome cycleGO:000709810.011
synapsisGO:000712910.011
apoptotic process involved in developmentGO:190274220.011
regulation of chromosome segregationGO:005198310.011
response to other organismGO:0051707970.011
regulation of receptor activityGO:001046920.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
osteoclast differentiationGO:003031610.011
cellular response to decreased oxygen levelsGO:003629410.011
macromolecular complex disassemblyGO:003298410.011
negative regulation of mapk cascadeGO:004340940.011
negative regulation of chromosome organizationGO:200125110.011
thermosensory behaviorGO:004004010.011
regulation of rna biosynthetic processGO:20011412130.011
regulation of neurotransmitter transportGO:005158810.011
immune system processGO:00023762410.011
regulation of multicellular organismal processGO:00512392770.011
positive regulation of stress activated mapk cascadeGO:003287430.011
biosynthetic processGO:00090582940.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
neuroblast proliferationGO:000740520.011
sequestering of metal ionGO:005123830.010
single organism cellular localizationGO:1902580460.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
transportGO:00068102200.010
regulation of macromolecule metabolic processGO:00602553170.010
intracellular transportGO:0046907320.010
leukocyte homeostasisGO:000177620.010
peptide metabolic processGO:000651810.010
rna biosynthetic processGO:00327741810.010
rna polyadenylationGO:004363120.010
pathway restricted smad protein phosphorylationGO:006038910.010
axis elongationGO:0003401310.010
activation of mapk activityGO:000018730.010
male meiosisGO:000714020.010
spindle assembly involved in mitosisGO:009030710.010
regulation of gtp catabolic processGO:003312420.010
exocytosisGO:000688710.010
blood vessel morphogenesisGO:00485142160.010
negative regulation of immune responseGO:005077720.010
positive regulation of map kinase activityGO:004340630.010
cellular response to unfolded proteinGO:003462020.010
establishment of protein localization to vacuoleGO:007266610.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010
response to light stimulusGO:0009416460.010
internal protein amino acid acetylationGO:000647520.010
endocrine hormone secretionGO:006098620.010
vacuole organizationGO:000703390.010

wipi2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.026
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.019
cancerDOID:16200.017
organ system cancerDOID:005068600.017
musculoskeletal system diseaseDOID:1700.016
cardiovascular system diseaseDOID:128700.013
muscle tissue diseaseDOID:6600.013
intrinsic cardiomyopathyDOID:006003600.013
cardiomyopathyDOID:005070000.013
myopathyDOID:42300.013
muscular diseaseDOID:008000000.013
heart diseaseDOID:11400.013
disease of metabolismDOID:001466700.012