Danio rerio

0 known processes

ppia

peptidylprolyl isomerase A (cyclophilin A)

(Aliases: fa93g09,wu:fb13h02,wu:fb05e11,Cyp1,wu:fa93g09,PPIA-2,wu:fb15a05)

ppia biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.573
locomotionGO:00400113130.199
microtubule organizing center organizationGO:003102310.186
cell deathGO:00082191210.143
Fly
programmed cell deathGO:00125011190.137
Fly
cellular component movementGO:00069283350.134
neuron developmentGO:00486662620.118
single fertilizationGO:000733830.109
cellular macromolecule metabolic processGO:00442603910.099
cell morphogenesisGO:00009022890.098
negative regulation of cellular metabolic processGO:0031324770.091
regulation of cellular metabolic processGO:00313233200.087
larval developmentGO:000216420.082
regulation of biological qualityGO:00650082630.081
apoptotic processGO:00069151160.079
energy reserve metabolic processGO:000611220.079
generation of neuronsGO:00486993850.078
cell surface receptor signaling pathwayGO:00071663250.078
single organism transportGO:00447652060.074
signal transductionGO:00071654550.072
heterocycle biosynthetic processGO:00181302150.071
regulation of primary metabolic processGO:00800903110.069
response to stressGO:00069502630.067
Zebrafish
cellular carbohydrate metabolic processGO:004426240.067
negative regulation of cellular processGO:00485232830.067
regulation of cell communicationGO:00106462320.065
positive regulation of programmed cell deathGO:0043068290.064
regulation of signalingGO:00230512350.064
regulation of biosynthetic processGO:00098892500.063
cell projection morphogenesisGO:00488582440.060
transcription dna templatedGO:00063511810.058
deathGO:00162651210.058
Fly
regulation of response to stimulusGO:00485832690.058
cellular component morphogenesisGO:00329893360.058
transportGO:00068102200.058
heterocycle metabolic processGO:00464832900.057
response to abiotic stimulusGO:00096281220.057
Zebrafish
gene expressionGO:00104672520.056
negative regulation of biological processGO:00485193040.056
regulation of nucleotide catabolic processGO:003081120.054
negative regulation of nucleobase containing compound metabolic processGO:0045934590.053
centrosome cycleGO:000709810.053
multicellular organism growthGO:003526440.052
single organism localizationGO:19025782250.051
response to chemicalGO:00422213200.051
cell morphogenesis involved in differentiationGO:00009041950.049
positive regulation of apoptotic signaling pathwayGO:200123510.049
positive regulation of camp metabolic processGO:003081620.049
aromatic compound biosynthetic processGO:00194382170.047
hemopoiesisGO:00300971830.046
regulation of purine nucleotide catabolic processGO:003312120.046
lipid storageGO:001991510.046
regulation of cell deathGO:00109411030.046
cellular biosynthetic processGO:00442492860.045
glucose homeostasisGO:004259310.045
cellular nitrogen compound biosynthetic processGO:00442712180.044
regulation of nucleobase containing compound metabolic processGO:00192192500.044
regulation of macromolecule biosynthetic processGO:00105562250.044
cell projection organizationGO:00300302840.043
positive regulation of apoptotic processGO:0043065290.042
nitrogen compound metabolic processGO:00068073190.042
protein metabolic processGO:00195381830.042
regulation of cell differentiationGO:00455951420.042
gastrulationGO:00073692080.042
cellular component biogenesisGO:00440851780.041
response to external stimulusGO:00096052640.041
response to temperature stimulusGO:0009266150.041
nucleobase containing compound biosynthetic processGO:00346542050.041
maintenance of locationGO:005123540.041
homeostatic processGO:00425921420.040
carboxylic acid metabolic processGO:0019752220.040
ribonucleotide biosynthetic processGO:0009260200.040
negative regulation of response to stimulusGO:00485851040.040
regulation of nitrogen compound metabolic processGO:00511712510.040
regulation of gene expressionGO:00104682650.039
cellular component disassemblyGO:002241110.039
centrosome duplicationGO:005129810.039
nucleobase containing compound metabolic processGO:00061392740.039
regulation of immune system processGO:0002682340.038
cellular nitrogen compound metabolic processGO:00346412900.038
modification dependent macromolecule catabolic processGO:004363230.037
intracellular signal transductionGO:0035556850.037
hematopoietic or lymphoid organ developmentGO:00485341910.036
protein complex subunit organizationGO:0071822460.036
regulation of metabolic processGO:00192223590.036
cellular response to stressGO:0033554620.036
immune system developmentGO:00025201910.035
embryo development ending in birth or egg hatchingGO:00097922710.035
regulation of cellular biosynthetic processGO:00313262450.035
rna biosynthetic processGO:00327741810.034
cellular aromatic compound metabolic processGO:00067252950.034
cell morphogenesis involved in neuron differentiationGO:00486671630.034
phagocytosisGO:000690930.034
positive regulation of catabolic processGO:000989640.034
cell part morphogenesisGO:00329902460.034
lipid homeostasisGO:005508830.033
response to woundingGO:00096111160.033
modification dependent protein catabolic processGO:001994130.033
centrosome organizationGO:005129710.033
gtp metabolic processGO:004603940.032
regulation of nucleoside metabolic processGO:000911820.032
regulation of cellular amino acid metabolic processGO:000652100.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
axon developmentGO:00615641660.032
regulation of bindingGO:005109830.031
central nervous system developmentGO:00074173870.031
cellular protein catabolic processGO:004425740.031
regulation of cellular macromolecule biosynthetic processGO:20001122220.031
nuclear migrationGO:000709730.031
nuclear transportGO:005116940.031
axonogenesisGO:00074091520.030
adult behaviorGO:003053420.030
positive regulation of cellular processGO:00485222010.030
organic acid metabolic processGO:0006082310.030
regulation of multicellular organismal processGO:00512392770.030
regionalizationGO:00030022740.030
regulation of cellular ketone metabolic processGO:001056570.030
stem cell maintenanceGO:001982740.029
neuron differentiationGO:00301823530.029
regulation of cytokine productionGO:000181730.029
guanosine containing compound metabolic processGO:190106840.028
erythrocyte differentiationGO:0030218540.028
carbohydrate homeostasisGO:003350010.028
cellular response to dna damage stimulusGO:0006974240.028
establishment of localizationGO:00512342440.028
zymogen activationGO:003163830.028
regulation of signal transductionGO:00099662250.028
regulation of cellular amine metabolic processGO:003323800.028
negative regulation of developmental processGO:0051093650.027
negative regulation of multicellular organismal processGO:0051241690.027
regulation of apoptotic processGO:0042981980.027
organelle assemblyGO:00709251100.027
regulation of metal ion transportGO:001095940.027
skin developmentGO:0043588540.027
regulation of programmed cell deathGO:00430671010.026
chordate embryonic developmentGO:00430092710.026
nucleic acid transportGO:005065720.026
organophosphate biosynthetic processGO:0090407230.026
cell migrationGO:00164772370.026
wound healingGO:0042060900.026
positive regulation of cell deathGO:0010942290.025
cellular protein metabolic processGO:00442671290.025
positive regulation of cellular catabolic processGO:003133130.025
regulation of multicellular organism growthGO:004001440.025
cell death in response to oxidative stressGO:003647320.025
microtubule based processGO:0007017600.025
sensory organ developmentGO:00074233930.025
cellular component assemblyGO:00226071700.025
regulation of molecular functionGO:0065009700.025
peptidyl serine phosphorylationGO:001810510.025
regulation of ion transportGO:0043269220.024
regulation of macromolecule metabolic processGO:00602553170.024
negative regulation of metabolic processGO:0009892860.024
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.024
cellular amine metabolic processGO:004410620.024
regulation of establishment of protein localizationGO:007020140.024
stem cell developmentGO:0048864820.024
single organism organelle organizationGO:19025891990.024
regulation of carbohydrate metabolic processGO:000610940.023
gtp catabolic processGO:000618420.023
regulation of response to stressGO:0080134360.023
organic cyclic compound biosynthetic processGO:19013622230.023
protein secretionGO:000930610.023
myeloid cell homeostasisGO:0002262560.023
oxidation reduction processGO:0055114410.023
organelle organizationGO:00069962270.023
eye developmentGO:00016542770.022
mitotic cell cycle processGO:1903047480.022
cellular ketone metabolic processGO:0042180110.022
positive regulation of secretionGO:005104710.022
cell cycle g1 s phase transitionGO:004484310.022
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.021
stem cell differentiationGO:00488631170.021
germ line stem cell maintenanceGO:003071820.021
negative regulation of protein phosphorylationGO:000193340.021
heart developmentGO:00075073130.021
establishment of protein localization to organelleGO:007259440.021
regulation of gtp catabolic processGO:003312420.021
nucleotide biosynthetic processGO:0009165210.021
chemotaxisGO:00069351040.021
ras protein signal transductionGO:000726570.021
cellular localizationGO:0051641970.021
regulation of oxidative stress induced cell deathGO:190320120.020
macromolecular complex subunit organizationGO:0043933740.020
regulation of developmental processGO:00507932470.020
negative regulation of apoptotic processGO:0043066550.020
cellular amino acid metabolic processGO:000652070.020
regulation of cell growthGO:0001558290.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
regulation of cellular component organizationGO:0051128860.020
nucleocytoplasmic transportGO:000691340.020
macromolecular complex assemblyGO:0065003350.020
negative regulation of signalingGO:0023057960.020
regulation of protein catabolic processGO:004217610.020
growthGO:00400071740.020
blood vessel developmentGO:00015682460.019
small molecule metabolic processGO:0044281770.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
dna catabolic processGO:000630810.019
g1 s transition of mitotic cell cycleGO:000008210.019
sexual reproductionGO:0019953360.019
regulation of protein complex assemblyGO:004325430.019
regulation of cellular carbohydrate metabolic processGO:001067540.019
organonitrogen compound metabolic processGO:1901564740.019
negative regulation of macromolecule metabolic processGO:0010605760.018
pronuclear migrationGO:003504610.018
extrinsic apoptotic signaling pathwayGO:009719130.018
rna metabolic processGO:00160702190.018
regulation of rna biosynthetic processGO:20011412130.018
neurological system processGO:0050877620.018
positive regulation of cellular amine metabolic processGO:003324000.018
amine metabolic processGO:000930820.018
nucleic acid metabolic processGO:00903042440.018
guanosine containing compound catabolic processGO:190106920.018
cell substrate junction assemblyGO:000704420.018
digestive tract morphogenesisGO:00485462310.018
oxoacid metabolic processGO:0043436310.018
camera type eye developmentGO:00430102220.018
regulation of nucleotide metabolic processGO:0006140170.017
macromolecular complex disassemblyGO:003298410.017
regulation of multicellular organismal developmentGO:20000262230.017
positive regulation of gtp catabolic processGO:003312610.017
proteasomal protein catabolic processGO:001049820.017
tube morphogenesisGO:00352393490.017
positive regulation of nucleoside metabolic processGO:004597910.017
apoptotic signaling pathwayGO:0097190230.017
protein complex disassemblyGO:004324110.017
protein localizationGO:0008104400.017
regulation of purine nucleotide biosynthetic processGO:1900371150.017
organic substance biosynthetic processGO:19015762890.017
blood vessel morphogenesisGO:00485142160.017
carbohydrate derivative biosynthetic processGO:1901137430.017
macromolecule localizationGO:0033036540.017
fertilizationGO:000956630.017
localization of cellGO:00516742440.017
cellular response to organic substanceGO:00713101050.017
spermatid differentiationGO:004851520.016
response to organic substanceGO:00100331530.016
adherens junction organizationGO:003433240.016
cell agingGO:000756920.016
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.016
cell cycleGO:0007049930.016
phosphorus metabolic processGO:00067931090.016
single organism metabolic processGO:00447102170.016
circulatory system processGO:0003013870.016
cytokinesisGO:000091030.016
positive regulation of protein complex assemblyGO:003133420.016
homeostasis of number of cellsGO:0048872620.016
meiotic cell cycle processGO:190304630.016
macromolecule biosynthetic processGO:00090592270.015
negative regulation of dna metabolic processGO:005105340.015
cilium morphogenesisGO:0060271850.015
negative regulation of cell communicationGO:0010648960.015
response to monosaccharideGO:003428430.015
cellular protein complex assemblyGO:0043623190.015
response to decreased oxygen levelsGO:0036293250.015
Zebrafish
mitotic cell cycleGO:0000278640.015
morphogenesis of an epitheliumGO:00020093330.015
meiotic nuclear divisionGO:000712640.015
positive regulation of secretion by cellGO:190353210.015
positive regulation of nucleotide catabolic processGO:003081310.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
negative regulation of signal transductionGO:0009968940.015
peptidyl serine modificationGO:001820920.015
negative regulation of cellular biosynthetic processGO:0031327550.015
regulation of rna metabolic processGO:00512522240.015
small gtpase mediated signal transductionGO:000726480.015
immune system processGO:00023762410.014
regulation of sequence specific dna binding transcription factor activityGO:005109090.014
positive regulation of cell communicationGO:0010647560.014
regulation of cytoplasmic transportGO:190364940.014
ubiquitin dependent protein catabolic processGO:000651130.014
protein modification processGO:00362111000.014
neuron projection morphogenesisGO:00488121610.014
pole plasm assemblyGO:000731540.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
positive regulation of biological processGO:00485182530.014
regulation of blood pressureGO:000821710.014
translational initiationGO:000641330.014
multi organism processGO:00517041340.014
positive regulation of map kinase activityGO:004340630.014
regulation of protein transportGO:005122330.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
cell motilityGO:00488702440.013
epithelial cell differentiationGO:00308551160.013
regulation of phosphate metabolic processGO:0019220430.013
cell cell signalingGO:0007267520.013
regulation of cellular protein metabolic processGO:0032268520.013
embryonic organ developmentGO:00485683810.013
cellular response to chemical stimulusGO:00708871570.013
negative regulation of protein kinase activityGO:000646940.013
response to oxygen levelsGO:0070482250.013
Zebrafish
regulation of gtpase activityGO:004308720.013
regulation of cellular protein catabolic processGO:190336210.013
regulation of dna metabolic processGO:0051052110.013
negative regulation of kinase activityGO:003367340.013
establishment of organelle localizationGO:0051656450.013
vasculature developmentGO:00019442780.013
dorsal ventral pattern formationGO:00099531250.013
positive regulation of response to stimulusGO:0048584800.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
organic substance transportGO:0071702580.013
biosynthetic processGO:00090582940.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
cell proliferationGO:0008283800.013
mitochondrion organizationGO:000700540.012
positive regulation of cellular component biogenesisGO:004408930.012
sensory perceptionGO:0007600390.012
leukocyte homeostasisGO:000177620.012
single organism nuclear importGO:190259330.012
negative regulation of macromolecule biosynthetic processGO:0010558480.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
organic cyclic compound metabolic processGO:19013603010.012
axon guidanceGO:0007411860.012
sensory perception of painGO:001923310.012
positive regulation of signal transductionGO:0009967560.012
protein localization to nucleusGO:003450430.012
regulation of protein complex disassemblyGO:004324410.012
negative regulation of programmed cell deathGO:0043069580.012
regulation of catalytic activityGO:0050790550.012
negative regulation of protein complex assemblyGO:003133310.012
positive regulation of cell adhesionGO:004578510.012
regulation of meiotic cell cycleGO:005144510.012
positive regulation of striated muscle tissue developmentGO:004584410.012
negative regulation of response to dna damage stimulusGO:200102130.012
cellular response to topologically incorrect proteinGO:003596720.012
striated muscle tissue developmentGO:00147061100.012
regulation of erythrocyte differentiationGO:004564620.012
wnt signaling pathwayGO:0016055800.012
mononuclear cell proliferationGO:003294310.012
segmentationGO:0035282970.012
regulation of intracellular protein transportGO:003315730.012
negative regulation of nucleic acid templated transcriptionGO:1903507450.012
regulation of transporter activityGO:003240920.012
negative regulation of biosynthetic processGO:0009890550.011
regulation of ras gtpase activityGO:003231820.011
positive regulation of wound healingGO:009030310.011
carbohydrate biosynthetic processGO:001605110.011
leukocyte proliferationGO:007066110.011
cellular response to biotic stimulusGO:007121630.011
carbohydrate derivative metabolic processGO:1901135610.011
macromolecule modificationGO:00434121110.011
taxisGO:00423301090.011
oocyte anterior posterior axis specificationGO:000731440.011
cellular protein modification processGO:00064641000.011
regulation of hydrolase activityGO:0051336280.011
lymphocyte proliferationGO:004665110.011
proteolysisGO:0006508380.011
regulation of localizationGO:00328791040.011
regulation of ion transmembrane transporter activityGO:003241220.011
positive regulation of cytoskeleton organizationGO:005149530.011
regenerationGO:0031099910.011
striated muscle cell differentiationGO:00511461290.011
digestive tract developmentGO:00485652650.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
regulation of protein metabolic processGO:0051246560.011
cell growthGO:0016049570.011
regulation of cyclic nucleotide metabolic processGO:0030799150.011
spermatid developmentGO:000728620.011
negative regulation of catabolic processGO:000989530.011
phagocytosis engulfmentGO:000691110.011
cellular macromolecule biosynthetic processGO:00346452240.011
ion transportGO:00068111140.011
developmental growth involved in morphogenesisGO:0060560860.010
purine nucleotide biosynthetic processGO:0006164200.010
protein importGO:001703830.010
system processGO:00030081850.010
regulation of cellular response to oxidative stressGO:190040720.010
cellular response to external stimulusGO:007149620.010
regulation of protein import into nucleusGO:004230620.010
alcohol biosynthetic processGO:004616520.010
nuclear importGO:005117030.010
positive regulation of myeloid cell differentiationGO:004563920.010
brain developmentGO:00074202930.010
cellular response to molecule of bacterial originGO:007121930.010

ppia disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
disease of metabolismDOID:001466700.022
nervous system diseaseDOID:86300.013