Danio rerio

11 known processes

LOC100538108

tissue-type plasminogen activator-like

LOC100538108 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic nuclear divisionGO:000712640.089
larval developmentGO:000216420.083
negative regulation of cellular processGO:00485232830.081
regulation of stem cell differentiationGO:200073640.078
stem cell proliferationGO:007208940.075
agingGO:000756820.074
negative regulation of biological processGO:00485193040.068
biosynthetic processGO:00090582940.064
regulation of protein complex assemblyGO:004325430.060
organic substance biosynthetic processGO:19015762890.058
sensory organ developmentGO:00074233930.057
nucleobase containing compound metabolic processGO:00061392740.056
regulation of reproductive processGO:200024140.055
hormone transportGO:000991420.053
organic cyclic compound metabolic processGO:19013603010.050
immune system processGO:00023762410.049
cellular nitrogen compound metabolic processGO:00346412900.047
regulation of metabolic processGO:00192223590.046
regulation of biological qualityGO:00650082630.046
regulation of epithelial cell proliferationGO:005067830.045
cellular biosynthetic processGO:00442492860.045
positive regulation of transportGO:005105020.043
cellular nitrogen compound biosynthetic processGO:00442712180.042
lipid storageGO:001991510.042
female sex differentiationGO:004666040.042
response to chemicalGO:00422213200.042
symbiosis encompassing mutualism through parasitismGO:004440340.041
response to external stimulusGO:00096052640.041
nitrogen compound metabolic processGO:00068073190.041
regulation of rna metabolic processGO:00512522240.041
positive regulation of cellular component biogenesisGO:004408930.040
positive regulation of cytokine productionGO:000181920.040
aromatic compound biosynthetic processGO:00194382170.040
maintenance of locationGO:005123540.039
hormone secretionGO:004687920.039
embryo development ending in birth or egg hatchingGO:00097922710.039
endocrine processGO:005088620.039
regulation of endocrine processGO:004406020.039
multicellular organism growthGO:003526440.038
organic cyclic compound biosynthetic processGO:19013622230.038
response to stressGO:00069502630.038
regulation of nitrogen compound metabolic processGO:00511712510.038
heterocycle biosynthetic processGO:00181302150.038
regulation of nucleobase containing compound metabolic processGO:00192192500.037
embryonic organ morphogenesisGO:00485622740.037
cellular macromolecule biosynthetic processGO:00346452240.037
signal transductionGO:00071654550.037
nucleic acid templated transcriptionGO:00976591810.037
rna metabolic processGO:00160702190.036
rna biosynthetic processGO:00327741810.035
nik nf kappab signalingGO:003806110.035
phagocytosisGO:000690930.035
locomotionGO:00400113130.035
single organism metabolic processGO:00447102170.035
small molecule metabolic processGO:0044281770.034
cellular aromatic compound metabolic processGO:00067252950.034
regulation of meiotic cell cycleGO:005144510.034
regulation of macromolecule biosynthetic processGO:00105562250.033
regulation of tube sizeGO:003515020.033
meiotic cell cycle processGO:190304630.033
regulation of stem cell proliferationGO:007209120.032
response to other organismGO:0051707970.032
brain developmentGO:00074202930.032
nucleoside monophosphate catabolic processGO:000912540.032
negative regulation of nuclear divisionGO:005178430.032
gene expressionGO:00104672520.032
transportGO:00068102200.031
endocrine hormone secretionGO:006098620.031
regulation of cellular metabolic processGO:00313233200.031
regulation of multicellular organismal processGO:00512392770.030
multi organism processGO:00517041340.030
regulation of nucleic acid templated transcriptionGO:19035062130.030
protein localization to nucleusGO:003450430.030
regulation of cellular biosynthetic processGO:00313262450.030
heterocycle metabolic processGO:00464832900.030
determination of bilateral symmetryGO:00098552040.030
response to drugGO:004249330.029
guanosine containing compound metabolic processGO:190106840.029
ion transmembrane transportGO:0034220910.029
androgen metabolic processGO:000820920.029
regulation of translational initiationGO:000644610.029
regulation of gene expressionGO:00104682650.029
hatchingGO:003518840.029
cellular component movementGO:00069283350.029
er nucleus signaling pathwayGO:000698420.029
nucleic acid metabolic processGO:00903042440.029
nuclear transportGO:005116940.028
rna localizationGO:000640340.028
multi organism cellular processGO:004476420.028
regionalizationGO:00030022740.028
development of primary female sexual characteristicsGO:004654540.028
system processGO:00030081850.028
regulation of sodium ion transportGO:000202820.028
single organism localizationGO:19025782250.027
establishment of localizationGO:00512342440.027
central nervous system developmentGO:00074173870.027
regulation of cytoplasmic transportGO:190364940.027
interspecies interaction between organismsGO:004441940.027
innate immune responseGO:0045087130.027
female gonad developmentGO:000858540.027
macromolecule biosynthetic processGO:00090592270.027
adult behaviorGO:003053420.027
positive regulation of cellular catabolic processGO:003133130.027
purine ribonucleoside monophosphate catabolic processGO:000916940.027
response to topologically incorrect proteinGO:003596620.027
chordate embryonic developmentGO:00430092710.027
lateral line system developmentGO:0048925760.026
regulation of primary metabolic processGO:00800903110.026
positive regulation of map kinase activityGO:004340630.026
organism emergence from protective structureGO:007168440.026
transcription dna templatedGO:00063511810.026
ribonucleoside monophosphate catabolic processGO:000915840.026
embryonic organ developmentGO:00485683810.026
nucleobase containing compound biosynthetic processGO:00346542050.025
specification of symmetryGO:00097992040.025
stem cell maintenanceGO:001982740.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
regulation of developmental processGO:00507932470.025
regulation of protein import into nucleusGO:004230620.025
purine nucleoside monophosphate catabolic processGO:000912840.025
regulation of cellular amine metabolic processGO:003323800.024
regulation of cytokine productionGO:000181730.024
cellular component assemblyGO:00226071700.024
cellular macromolecule metabolic processGO:00442603910.024
regulation of rna biosynthetic processGO:20011412130.024
regulation of establishment of protein localizationGO:007020140.024
cell surface receptor signaling pathwayGO:00071663250.024
regulation of transcription dna templatedGO:00063552130.024
regulation of blood vessel sizeGO:005088020.024
androgen biosynthetic processGO:000670210.023
positive regulation of cell cycleGO:004578730.023
regulation of cell projection assemblyGO:006049140.023
response to external biotic stimulusGO:0043207970.023
positive regulation of leukocyte mediated cytotoxicityGO:000191210.023
carboxylic acid metabolic processGO:0019752220.023
regulation of protein localization to nucleusGO:190018020.023
positive regulation of stress activated mapk cascadeGO:003287430.023
cell substrate adhesionGO:003158940.023
transcription from rna polymerase ii promoterGO:0006366800.023
positive regulation of biological processGO:00485182530.023
regulation of response to stimulusGO:00485832690.023
negative regulation of gene expressionGO:0010629650.023
atp catabolic processGO:000620040.022
positive regulation of cytoskeleton organizationGO:005149530.022
cellular component disassemblyGO:002241110.022
regulation of cell activationGO:005086510.022
organic acid metabolic processGO:0006082310.022
regulation of cellular amino acid metabolic processGO:000652100.022
multicellular organismal response to stressGO:003355520.022
regulation of signalingGO:00230512350.022
meiosis iGO:000712710.021
cell motilityGO:00488702440.021
regulation of macromolecule metabolic processGO:00602553170.021
positive regulation of catabolic processGO:000989640.021
negative regulation of cellular metabolic processGO:0031324770.021
embryonic skeletal system developmentGO:0048706970.021
regulation of signal transductionGO:00099662250.021
regulation of hormone secretionGO:004688320.021
peptide metabolic processGO:000651810.021
positive regulation of blood circulationGO:190352420.020
synaptic growth at neuromuscular junctionGO:005112420.020
amine metabolic processGO:000930820.020
hematopoietic or lymphoid organ developmentGO:00485341910.020
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.020
transmembrane transportGO:00550851200.020
regulation of wound healingGO:006104120.020
negative regulation of cellular biosynthetic processGO:0031327550.020
negative regulation of protein complex assemblyGO:003133310.020
negative regulation of macromolecule metabolic processGO:0010605760.020
positive regulation of lymphocyte mediated immunityGO:000270810.020
regulation of synapse assemblyGO:005196330.020
protein polymerizationGO:005125840.020
hormone biosynthetic processGO:004244630.019
gtp metabolic processGO:004603940.019
leukocyte proliferationGO:007066110.019
regulation of nucleocytoplasmic transportGO:004682220.019
positive regulation of secretion by cellGO:190353210.019
fatty acid transportGO:001590810.019
somite developmentGO:0061053960.019
negative regulation of biosynthetic processGO:0009890550.019
hematopoietic stem cell differentiationGO:0060218200.019
ion transportGO:00068111140.019
gtp catabolic processGO:000618420.019
stem cell differentiationGO:00488631170.019
regulation of myotube differentiationGO:001083020.019
phosphorus metabolic processGO:00067931090.019
regulation of synapse organizationGO:005080730.019
response to biotic stimulusGO:0009607970.019
axon ensheathment in central nervous systemGO:003229120.019
muscle cell developmentGO:00550011150.019
cell morphogenesisGO:00009022890.018
negative regulation of protein phosphorylationGO:000193340.018
regulation of cell shapeGO:000836010.018
regulation of blood pressureGO:000821710.018
regulation of systemic arterial blood pressureGO:000307310.018
positive regulation of secretionGO:005104710.018
regulation of metal ion transportGO:001095940.018
negative regulation of kinase activityGO:003367340.018
mechanosensory lateral line system developmentGO:0048881490.018
zymogen activationGO:003163830.018
protein metabolic processGO:00195381830.018
lateral inhibitionGO:004633110.018
cellular amine metabolic processGO:004410620.018
camera type eye developmentGO:00430102220.018
synaptic target recognitionGO:000803910.018
embryonic skeletal system morphogenesisGO:0048704930.017
establishment of protein localization to organelleGO:007259440.017
cellular response to topologically incorrect proteinGO:003596720.017
regulation of nucleoside metabolic processGO:000911820.017
plasminogen activationGO:003163930.017
appendage developmentGO:0048736800.017
anterior posterior pattern specificationGO:00099521520.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
dorsal ventral pattern formationGO:00099531250.017
secondary metabolic processGO:001974830.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
homeostatic processGO:00425921420.017
regulation of skeletal muscle tissue developmentGO:004864140.017
single organism transportGO:00447652060.017
positive regulation of cellular processGO:00485222010.017
hemopoiesisGO:00300971830.017
response to unfolded proteinGO:000698620.017
calcium ion importGO:007050940.017
regulation of biosynthetic processGO:00098892500.016
lymphocyte proliferationGO:004665110.016
negative regulation of nitrogen compound metabolic processGO:0051172590.016
somitogenesisGO:0001756870.016
positive regulation of response to stimulusGO:0048584800.016
morphogenesis of an epitheliumGO:00020093330.016
regulation of cell communicationGO:00106462320.016
response to glucocorticoidGO:005138410.016
single organism organelle organizationGO:19025891990.016
leukocyte mediated cytotoxicityGO:000190910.016
fin developmentGO:0033333770.016
protein importGO:001703830.016
neurotransmitter secretionGO:000726920.016
neuromast developmentGO:0048884460.016
connective tissue developmentGO:0061448990.016
ovulation cycle processGO:002260220.016
sensory system developmentGO:0048880760.016
mononuclear cell proliferationGO:003294310.015
cell killingGO:000190620.015
nuclear importGO:005117030.015
cellular monovalent inorganic cation homeostasisGO:003000420.015
oxoacid metabolic processGO:0043436310.015
regulation of intracellular protein transportGO:003315730.015
somatic muscle developmentGO:000752540.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
generation of neuronsGO:00486993850.015
regulation of transmembrane transporter activityGO:002289820.015
cellular component biogenesisGO:00440851780.015
organonitrogen compound metabolic processGO:1901564740.015
gas transportGO:001566930.015
positive regulation of protein complex assemblyGO:003133420.015
localization of cellGO:00516742440.015
regulation of protein catabolic processGO:004217610.015
long chain fatty acid transportGO:001590910.015
positive regulation of cell activationGO:005086710.015
positive regulation of immune effector processGO:000269930.015
macromolecular complex disassemblyGO:003298410.015
cortical cytoskeleton organizationGO:003086510.015
cellular amino acid metabolic processGO:000652070.015
meiotic chromosome segregationGO:004513230.015
organelle organizationGO:00069962270.015
single organism nuclear importGO:190259330.015
lipid catabolic processGO:001604240.015
cellular response to molecule of bacterial originGO:007121930.015
negative regulation of reproductive processGO:200024230.015
negative regulation of metabolic processGO:0009892860.015
muscle structure developmentGO:00610611960.015
cellular component morphogenesisGO:00329893360.015
regulation of multicellular organismal developmentGO:20000262230.015
tissue remodelingGO:004877140.015
gastrulationGO:00073692080.015
appendage morphogenesisGO:0035107560.015
negative regulation of cytoplasmic transportGO:190365020.015
carbohydrate biosynthetic processGO:001605110.015
regulation of ion transmembrane transporter activityGO:003241220.014
regulation of protein polymerizationGO:003227120.014
cellular response to unfolded proteinGO:003462020.014
response to corticosteroidGO:003196010.014
germ line stem cell maintenanceGO:003071820.014
neurotransmitter transportGO:000683620.014
regulation of cellular ketone metabolic processGO:001056570.014
olfactory bulb developmentGO:002177240.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
peptidyl serine modificationGO:001820920.014
centrosome organizationGO:005129710.014
positive regulation of cellular metabolic processGO:0031325940.014
aorta developmentGO:003590440.014
cellular hormone metabolic processGO:0034754190.014
inorganic cation transmembrane transportGO:0098662500.014
nucleocytoplasmic transportGO:000691340.014
regulation of natural killer cell mediated immunityGO:000271510.014
cytoplasm organizationGO:000702840.014
phosphate containing compound metabolic processGO:00067961080.014
phagocytosis engulfmentGO:000691110.014
guanosine containing compound catabolic processGO:190106920.014
negative regulation of mapk cascadeGO:004340940.014
cellular response to radiationGO:007147840.014
negative regulation of defense responseGO:003134820.014
viral processGO:001603210.014
pole plasm assemblyGO:000731540.014
regulation of purine nucleotide catabolic processGO:003312120.014
membrane invaginationGO:001032410.014
response to monosaccharideGO:003428430.014
protein dephosphorylationGO:000647030.014
photoreceptor cell fate specificationGO:004370410.014
male meiosisGO:000714020.014
protein acetylationGO:000647320.014
translational initiationGO:000641330.014
cellular amide metabolic processGO:004360340.014
regulation of nucleotide catabolic processGO:003081120.014
protein targeting to nucleusGO:004474430.013
cell cycle g1 s phase transitionGO:004484310.013
response to xenobiotic stimulusGO:0009410450.013
positive regulation of cellular amine metabolic processGO:003324000.013
cognitionGO:005089010.013
immune system developmentGO:00025201910.013
long chain fatty acid metabolic processGO:000167610.013
positive regulation of dna metabolic processGO:005105410.013
water transportGO:0006833150.013
skeletal system developmentGO:00015011810.013
digestive tract morphogenesisGO:00485462310.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
regulation of multicellular organism growthGO:004001440.013
regulation of reactive oxygen species metabolic processGO:200037720.013
determination of left right symmetryGO:00073681790.013
cartilage developmentGO:0051216960.013
regulation of bindingGO:005109830.013
calcium mediated signalingGO:001972220.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
lateral line developmentGO:0048882660.013
cytoskeleton organizationGO:0007010960.013
regulation of circadian rhythmGO:004275240.013
positive regulation of epithelial cell migrationGO:001063420.013
cellular response to external stimulusGO:007149620.013
ovulation cycleGO:004269820.013
cellular ketone metabolic processGO:0042180110.013
regulation of response to extracellular stimulusGO:003210410.013
peptidyl lysine acetylationGO:001839420.013
apical junction assemblyGO:004329710.013
epidermal cell fate specificationGO:000995740.013
membrane lipid biosynthetic processGO:004646720.013
regulation of oocyte developmentGO:006028130.013
regulation of protein targetingGO:190353320.013
regulation of inflammatory responseGO:005072720.013
regulation of filopodium assemblyGO:005148920.013
protein complex disassemblyGO:004324110.012
response to glucoseGO:000974930.012
regulation of gtpase activityGO:004308720.012
eye developmentGO:00016542770.012
striated muscle cell developmentGO:00550021080.012
cell proliferationGO:0008283800.012
nitric oxide biosynthetic processGO:000680920.012
golgi vesicle transportGO:004819330.012
multicellular organismal metabolic processGO:004423620.012
cellular response to biotic stimulusGO:007121630.012
diterpenoid metabolic processGO:0016101150.012
positive regulation of reproductive processGO:200024320.012
negative regulation of nucleobase containing compound metabolic processGO:0045934590.012
small molecule catabolic processGO:004428230.012
isoprenoid metabolic processGO:0006720150.012
protein acylationGO:004354330.012
mesenchymal cell differentiationGO:0048762870.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
response to organic substanceGO:00100331530.012
negative regulation of chromosome organizationGO:200125110.012
embryonic heart tube developmentGO:00350501330.012
cation transmembrane transportGO:0098655650.012
regulation of transporter activityGO:003240920.012
skeletal system morphogenesisGO:00487051020.012
nuclear exportGO:005116810.012
positive regulation of nucleoside metabolic processGO:004597910.012
cortical actin cytoskeleton organizationGO:003086610.012
synaptic vesicle localizationGO:009747910.012
cellular localizationGO:0051641970.012
response to ketoneGO:190165410.012
regulation of neurotransmitter secretionGO:004692810.012
chemosensory behaviorGO:000763510.012
regulation of cellular protein catabolic processGO:190336210.012
internal peptidyl lysine acetylationGO:001839320.012
negative regulation of secretionGO:005104820.012
internal protein amino acid acetylationGO:000647520.012
membrane repolarizationGO:008600920.012
protein import into nucleusGO:000660630.012
nephron epithelium morphogenesisGO:007208810.012
negative regulation of multi organism processGO:004390130.012
cell cycle arrestGO:000705010.012
fatty acid biosynthetic processGO:000663340.011
pyruvate metabolic processGO:000609010.011
muscle cell migrationGO:001481240.011
anion transportGO:0006820380.011
response to nutrientGO:000758430.011
regulation of skeletal muscle fiber developmentGO:004874220.011
interaction with hostGO:005170140.011
cell part morphogenesisGO:00329902460.011
regulation of receptor activityGO:001046920.011
positive regulation of leukocyte mediated immunityGO:000270510.011
one carbon compound transportGO:0019755140.011
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.011
regulation of dendrite morphogenesisGO:004881430.011
digestive tract developmentGO:00485652650.011
positive regulation of epithelial cell proliferationGO:005067910.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
fertilizationGO:000956630.011
sulfate transmembrane transportGO:190235820.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
positive regulation of histone modificationGO:003105810.011
positive regulation of protein polymerizationGO:003227320.011
negative regulation of protein kinase activityGO:000646940.011
single fertilizationGO:000733830.011
regulation of localizationGO:00328791040.011
b cell activationGO:004211320.011
cell morphogenesis involved in differentiationGO:00009041950.011
hepaticobiliary system developmentGO:0061008980.011
negative regulation of rna biosynthetic processGO:1902679450.011
regulation of protein transportGO:005122330.011
response to hexoseGO:000974630.011
regulation of immune system processGO:0002682340.011
regulation of molecular functionGO:0065009700.011
lipid metabolic processGO:0006629520.011
amino acid transportGO:000686520.011
regulation of steroid hormone secretionGO:200083110.011
negative regulation of intracellular transportGO:003238730.011
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.011
tube morphogenesisGO:00352393490.011
organic substance transportGO:0071702580.011
developmental programmed cell deathGO:001062340.011
intracellular mrna localizationGO:000829810.011
regulation of cellular component organizationGO:0051128860.011
segmentationGO:0035282970.011
compound eye developmentGO:004874920.011
regulation of lipid transportGO:003236840.011
cell agingGO:000756920.011
sequestering of metal ionGO:005123830.011
wnt signaling pathwayGO:0016055800.011
cellular protein catabolic processGO:004425740.011
positive regulation of cell killingGO:003134320.011
cell projection morphogenesisGO:00488582440.011
monocarboxylic acid catabolic processGO:007232930.011
carbon dioxide transportGO:001567030.011
liver developmentGO:0001889960.011
positive regulation of nucleotide catabolic processGO:003081310.011
head developmentGO:00603223030.011
proepicardium developmentGO:000334240.011
regulation of hematopoietic progenitor cell differentiationGO:190153210.010
negative regulation of protein localization to nucleusGO:190018120.010
reactive nitrogen species metabolic processGO:200105700.010
negative regulation of macromolecule biosynthetic processGO:0010558480.010
positive regulation of chromosome organizationGO:200125210.010
negative regulation of secretion by cellGO:190353120.010
response to vitaminGO:003327330.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
astrocyte differentiationGO:004870810.010
terpenoid metabolic processGO:0006721150.010
negative regulation of epithelial cell proliferationGO:005068010.010
positive regulation of multicellular organismal processGO:0051240520.010
protein homooligomerizationGO:005126030.010
synaptic vesicle transportGO:004848910.010
gland developmentGO:00487321430.010
endoplasmic reticulum unfolded protein responseGO:003096820.010
positive regulation of macromolecule metabolic processGO:0010604930.010
cellular carbohydrate metabolic processGO:004426240.010
cellular aldehyde metabolic processGO:000608140.010
negative regulation of protein transportGO:005122430.010
carbohydrate homeostasisGO:003350010.010
regulation of muscle contractionGO:000693730.010
nephron morphogenesisGO:007202820.010
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.010
g1 s transition of mitotic cell cycleGO:000008210.010
somatic stem cell maintenanceGO:003501910.010
digestive system developmentGO:00551232890.010
neuroblast proliferationGO:000740520.010
muscle fiber developmentGO:0048747520.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
response to light stimulusGO:0009416460.010
actin filament based movementGO:003004810.010
cell cell recognitionGO:000998810.010
circulatory system processGO:0003013870.010
negative regulation of nucleic acid templated transcriptionGO:1903507450.010
cation transportGO:0006812810.010

LOC100538108 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
disease of metabolismDOID:001466700.016
disease of cellular proliferationDOID:1456600.015
nervous system diseaseDOID:86300.012
cancerDOID:16200.011
musculoskeletal system diseaseDOID:1700.011
inherited metabolic disorderDOID:65500.010
sensory system diseaseDOID:005015500.010
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010