Danio rerio

19 known processes

fancd2

Fanconi anemia, complementation group D2

fancd2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glomerular visceral epithelial cell fate commitmentGO:007214940.311
regulation of biological qualityGO:00650082630.223
maintenance of locationGO:005123540.174
cell cycle g1 s phase transitionGO:004484310.154
mitotic cell cycle processGO:1903047480.145
cell proliferation involved in heart morphogenesisGO:006132320.143
g1 s transition of mitotic cell cycleGO:000008210.141
determination of bilateral symmetryGO:00098552040.139
segment polarity determinationGO:000736710.130
b cell differentiationGO:003018310.123
ventricular cardiac muscle tissue developmentGO:000322930.118
heart morphogenesisGO:00030071560.117
i kappab kinase nf kappab signalingGO:000724940.116
striated muscle tissue developmentGO:00147061100.115
cognitionGO:005089010.110
regulation of cell shapeGO:000836010.107
pronuclear migrationGO:003504610.104
gastrulationGO:00073692080.102
determination of left right symmetryGO:00073681790.100
ventricular cardiac muscle tissue morphogenesisGO:005501020.099
organic substance biosynthetic processGO:19015762890.094
stem cell divisionGO:001714510.094
single organism organelle organizationGO:19025891990.091
Mouse
regulation of signal transductionGO:00099662250.090
embryo development ending in birth or egg hatchingGO:00097922710.087
specification of symmetryGO:00097992040.085
organelle organizationGO:00069962270.085
Mouse
regulation of multicellular organism growthGO:004001440.084
muscle structure developmentGO:00610611960.083
regulation of developmental processGO:00507932470.074
positive regulation of muscle cell differentiationGO:005114910.073
heterocycle biosynthetic processGO:00181302150.073
regulation of rna metabolic processGO:00512522240.072
nucleocytoplasmic transportGO:000691340.072
outflow tract morphogenesisGO:000315110.071
auditory receptor cell fate commitmentGO:000991240.071
response to external stimulusGO:00096052640.070
macromolecule biosynthetic processGO:00090592270.069
single organism transportGO:00447652060.068
single organism localizationGO:19025782250.066
nuclear importGO:005117030.066
periodic partitioningGO:000736510.064
regulation of dna replicationGO:000627530.063
hemopoiesisGO:00300971830.062
cellular response to dna damage stimulusGO:0006974240.061
Mouse
angiogenesisGO:00015251580.060
cellular biosynthetic processGO:00442492860.059
regulation of cellular biosynthetic processGO:00313262450.057
positive regulation of cell cycleGO:004578730.057
sensory organ developmentGO:00074233930.057
circadian sleep wake cycle sleepGO:005080210.056
specification of organ identityGO:001009220.055
cellular aromatic compound metabolic processGO:00067252950.055
sequestering of metal ionGO:005123830.055
negative regulation of biological processGO:00485193040.055
endocardial cushion formationGO:000327220.054
positive regulation of nucleobase containing compound metabolic processGO:0045935690.054
regulation of nucleocytoplasmic transportGO:004682220.054
central nervous system developmentGO:00074173870.052
developmental growthGO:00485891660.052
protein modification processGO:00362111000.052
multicellular organism growthGO:003526440.051
positive regulation of striated muscle cell differentiationGO:005115510.051
vasculature developmentGO:00019442780.050
positive regulation of muscle tissue developmentGO:190186310.050
cell morphogenesis involved in differentiationGO:00009041950.050
embryonic organ developmentGO:00485683810.050
endothelial cell fate commitmentGO:006083930.050
establishment of localizationGO:00512342440.050
nitrogen compound metabolic processGO:00068073190.050
striated muscle cell differentiationGO:00511461290.049
germ line stem cell divisionGO:004207810.049
regulation of protein localization to nucleusGO:190018020.049
regulation of organ growthGO:004662030.049
regulation of biosynthetic processGO:00098892500.048
negative regulation of gene expressionGO:0010629650.048
nuclear transportGO:005116940.048
rna metabolic processGO:00160702190.048
regulation of cytoplasmic transportGO:190364940.047
heterocycle metabolic processGO:00464832900.047
chordate embryonic developmentGO:00430092710.047
regulation of synapse organizationGO:005080730.045
metal ion transportGO:0030001580.045
taxisGO:00423301090.044
larval developmentGO:000216420.044
regulation of cell proliferation involved in heart morphogenesisGO:200013620.044
regulation of organelle assemblyGO:190211540.043
digestive tract developmentGO:00485652650.043
head developmentGO:00603223030.043
single fertilizationGO:000733830.042
biosynthetic processGO:00090582940.041
regulation of cell differentiationGO:00455951420.041
cellular nitrogen compound metabolic processGO:00346412900.041
cellular response to external stimulusGO:007149620.041
mitotic dna integrity checkpointGO:004477440.040
blood vessel morphogenesisGO:00485142160.040
negative regulation of cellular processGO:00485232830.040
mitotic g2 dna damage checkpointGO:000709530.039
protein import into nucleusGO:000660630.039
protein polymerizationGO:005125840.038
anterior posterior pattern specificationGO:00099521520.038
muscle organ developmentGO:00075171010.038
regulation of establishment of protein localizationGO:007020140.038
b cell activationGO:004211320.038
phagocytosisGO:000690930.038
regulation of wound healingGO:006104120.038
regulation of transcription dna templatedGO:00063552130.038
regulation of nucleotide catabolic processGO:003081120.038
meiotic cell cycle processGO:190304630.037
Mouse
macromolecule modificationGO:00434121110.037
neurological system processGO:0050877620.037
cell cycleGO:0007049930.037
Mouse
response to stressGO:00069502630.036
Mouse
regionalizationGO:00030022740.036
muscle cell differentiationGO:00426921390.036
regulation of nitrogen compound metabolic processGO:00511712510.036
regulation of muscle contractionGO:000693730.036
organic cyclic compound metabolic processGO:19013603010.036
wound healingGO:0042060900.035
transportGO:00068102200.035
regulation of response to stimulusGO:00485832690.035
regulation of protein ubiquitinationGO:003139630.035
protein localization to nucleusGO:003450430.035
cellular nitrogen compound biosynthetic processGO:00442712180.035
establishment of protein localization to organelleGO:007259440.035
negative regulation of macromolecule metabolic processGO:0010605760.034
fertilizationGO:000956630.034
regulation of primary metabolic processGO:00800903110.034
aorta developmentGO:003590440.034
proteolysis involved in cellular protein catabolic processGO:005160330.033
cytoskeleton organizationGO:0007010960.033
response to chemicalGO:00422213200.033
arterial endothelial cell differentiationGO:006084220.033
tube morphogenesisGO:00352393490.033
nucleic acid templated transcriptionGO:00976591810.032
single organism biosynthetic processGO:0044711710.032
segmentationGO:0035282970.032
single organism cellular localizationGO:1902580460.032
negative regulation of nitrogen compound metabolic processGO:0051172590.031
response to transition metal nanoparticleGO:1990267280.031
morphogenesis of an epitheliumGO:00020093330.031
regulation of macromolecule metabolic processGO:00602553170.031
regulation of multicellular organismal processGO:00512392770.031
ubiquitin dependent protein catabolic processGO:000651130.031
cell motilityGO:00488702440.031
regulation of metabolic processGO:00192223590.031
establishment of localization in cellGO:0051649770.031
mesenchymal cell differentiationGO:0048762870.031
tissue remodelingGO:004877140.031
cellular localizationGO:0051641970.030
nuclear migrationGO:000709730.030
homeostatic processGO:00425921420.030
regulation of transcription from rna polymerase ii promoterGO:00063571140.030
negative regulation of intracellular transportGO:003238730.030
autophagyGO:000691440.030
muscle tissue developmentGO:00605371100.030
positive regulation of biological processGO:00485182530.030
signal transductionGO:00071654550.030
single organism metabolic processGO:00447102170.030
muscle fiber developmentGO:0048747520.030
membrane fusionGO:006102520.029
deathGO:00162651210.029
cortical cytoskeleton organizationGO:003086510.029
mitotic dna damage checkpointGO:004477340.029
regulation of bmp signaling pathwayGO:0030510390.029
negative regulation of protein phosphorylationGO:000193340.029
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.028
mesenchymal cell developmentGO:0014031780.028
regulation of protein targetingGO:190353320.028
keratinocyte differentiationGO:003021600.028
protein metabolic processGO:00195381830.028
regulation of cellular carbohydrate metabolic processGO:001067540.028
mitotic cell cycleGO:0000278640.028
protein importGO:001703830.028
regulation of wnt signaling pathway involved in heart developmentGO:000330720.028
positive regulation of cell divisionGO:005178120.028
mesenchyme developmentGO:00604851270.027
endocardium morphogenesisGO:000316040.027
blood vessel endothelial cell differentiationGO:006083720.027
regulation of cytoskeleton organizationGO:0051493110.027
regulation of reactive oxygen species metabolic processGO:200037720.027
cortical actin cytoskeleton organizationGO:003086610.027
heart developmentGO:00075073130.027
protein acetylationGO:000647320.026
cellular macromolecule metabolic processGO:00442603910.026
determination of heart left right asymmetryGO:00613711170.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
macroautophagyGO:001623610.026
proteasomal protein catabolic processGO:001049820.026
protein secretionGO:000930610.026
organic cyclic compound biosynthetic processGO:19013622230.026
aorta morphogenesisGO:003590930.026
defense response to other organismGO:0098542330.026
negative regulation of kinase activityGO:003367340.025
regulation of cellular component organizationGO:0051128860.025
myeloid cell homeostasisGO:0002262560.025
positive regulation of canonical wnt signaling pathwayGO:009026340.025
intracellular signal transductionGO:0035556850.025
regulation of microtubule cytoskeleton organizationGO:007050730.025
pronephric duct developmentGO:0039022130.025
cellular response to stressGO:0033554620.025
Mouse
modification dependent macromolecule catabolic processGO:004363230.024
negative regulation of cellular biosynthetic processGO:0031327550.024
trabecula morphogenesisGO:006138320.024
regulation of protein catabolic processGO:004217610.024
zinc ion transportGO:000682920.024
positive regulation of transportGO:005105020.024
reflexGO:006000420.024
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.023
skeletal muscle fiber developmentGO:0048741350.023
positive regulation of purine nucleotide catabolic processGO:003312310.023
regulation of protein transportGO:005122330.023
negative regulation of protein kinase activityGO:000646940.023
growthGO:00400071740.023
regulation of cell cycleGO:0051726520.023
cell morphogenesisGO:00009022890.023
dna alkylationGO:000630580.023
gene expressionGO:00104672520.023
nephric duct developmentGO:0072176130.022
cell substrate adhesionGO:003158940.022
secondary metabolic processGO:001974830.022
sensory perception of chemical stimulusGO:000760630.022
response to external biotic stimulusGO:0043207970.022
lateral inhibitionGO:004633110.022
epidermal cell fate specificationGO:000995740.022
canonical wnt signaling pathway involved in heart developmentGO:006131610.022
cellular component morphogenesisGO:00329893360.022
adrenal gland developmentGO:0030325100.022
meiotic chromosome segregationGO:004513230.022
nucleobase containing compound biosynthetic processGO:00346542050.022
negative regulation of protein kinase b signalingGO:005189820.021
regulation of cardiac muscle tissue developmentGO:005502410.021
regulation of protein modification by small protein conjugation or removalGO:190332030.021
somitogenesisGO:0001756870.021
digestive tract morphogenesisGO:00485462310.021
positive regulation of multicellular organismal processGO:0051240520.021
cellular macromolecule biosynthetic processGO:00346452240.020
multi organism processGO:00517041340.020
Mouse
epithelial to mesenchymal transitionGO:0001837210.020
regulation of intracellular protein transportGO:003315730.020
negative regulation of biosynthetic processGO:0009890550.020
positive regulation of cellular catabolic processGO:003133130.020
positive regulation of cellular component biogenesisGO:004408930.020
cation transportGO:0006812810.020
inner ear receptor cell fate commitmentGO:006012040.020
regulation of protein import into nucleusGO:004230620.020
stem cell proliferationGO:007208940.020
nucleobase containing compound metabolic processGO:00061392740.020
cellular response to extracellular stimulusGO:003166820.020
glomerular epithelium developmentGO:0072010120.019
negative regulation of transcription dna templatedGO:0045892450.019
regulation of mrna processingGO:005068430.019
nucleic acid metabolic processGO:00903042440.019
system processGO:00030081850.019
regulation of signalingGO:00230512350.019
regulation of organelle organizationGO:0033043290.019
regulation of macromolecule biosynthetic processGO:00105562250.019
heart loopingGO:0001947940.019
guanosine containing compound metabolic processGO:190106840.019
regulation of mitotic cell cycle phase transitionGO:190199080.019
positive regulation of striated muscle tissue developmentGO:004584410.019
negative regulation of rna biosynthetic processGO:1902679450.019
gtp catabolic processGO:000618420.019
protein complex localizationGO:003150310.019
mitochondrion organizationGO:000700540.019
regulation of nucleic acid templated transcriptionGO:19035062130.019
regulation of gene expressionGO:00104682650.019
cellular response to nutrient levelsGO:003166920.019
carboxylic acid metabolic processGO:0019752220.019
negative regulation of protein transportGO:005122430.018
stem cell developmentGO:0048864820.018
transcription dna templatedGO:00063511810.018
oxoacid metabolic processGO:0043436310.018
organic acid metabolic processGO:0006082310.018
organelle localizationGO:0051640490.018
determination of left right asymmetry in lateral mesodermGO:0003140200.018
transcription from rna polymerase ii promoterGO:0006366800.018
brain developmentGO:00074202930.018
sensory perceptionGO:0007600390.018
positive regulation of neuron deathGO:190121610.018
mitotic g2 m transition checkpointGO:004481830.018
digestive system developmentGO:00551232890.018
response to biotic stimulusGO:0009607970.018
cellular response to chemical stimulusGO:00708871570.018
stem cell maintenanceGO:001982740.017
regulation of epithelial cell proliferationGO:005067830.017
regulation of myotube differentiationGO:001083020.017
retinal rod cell developmentGO:004654840.017
regulation of circadian rhythmGO:004275240.017
response to inorganic substanceGO:0010035380.017
regulation of cellular component movementGO:0051270550.017
neuron differentiationGO:00301823530.017
central nervous system neuron axonogenesisGO:0021955180.017
circulatory system processGO:0003013870.017
aromatic compound biosynthetic processGO:00194382170.017
somatic stem cell maintenanceGO:003501910.017
intracellular transportGO:0046907320.017
embryonic heart tube developmentGO:00350501330.017
blood vessel developmentGO:00015682460.017
regulation of dendrite developmentGO:005077330.016
eye developmentGO:00016542770.016
regulation of rna biosynthetic processGO:20011412130.016
heart trabecula morphogenesisGO:006138420.016
cellular process involved in reproduction in multicellular organismGO:0022412280.016
regulation of autophagyGO:001050630.016
regulation of cellular protein catabolic processGO:190336210.016
programmed cell deathGO:00125011190.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
protein targeting to nucleusGO:004474430.016
transcription elongation from rna polymerase ii promoterGO:000636830.016
adult behaviorGO:003053420.016
g2 dna damage checkpointGO:003157230.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
regulation of multicellular organismal developmentGO:20000262230.016
invagination involved in gastrulation with mouth forming secondGO:005510910.016
rna biosynthetic processGO:00327741810.016
sensory organ morphogenesisGO:00905962000.016
peptidyl lysine acetylationGO:001839420.016
regulation of cell projection assemblyGO:006049140.016
regulation of cellular metabolic processGO:00313233200.016
notch signaling pathwayGO:0007219350.016
neuroblast differentiationGO:001401610.016
cytoskeleton dependent cytokinesisGO:006164030.016
actin filament based processGO:0030029640.015
protein acylationGO:004354330.015
regulation of cytokine productionGO:000181730.015
dorsal aorta developmentGO:003590740.015
negative regulation of metabolic processGO:0009892860.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
regulation of localizationGO:00328791040.015
response to other organismGO:0051707970.015
spindle assembly involved in meiosisGO:009030610.015
nuclear divisionGO:0000280230.015
Mouse
cellular response to starvationGO:000926710.015
cellular carbohydrate metabolic processGO:004426240.015
regulation of gtp catabolic processGO:003312420.015
regulation of cardiac muscle cell differentiationGO:200072510.015
regulation of synapse assemblyGO:005196330.015
regulation of bindingGO:005109830.015
phosphorylationGO:0016310690.015
i kappab phosphorylationGO:000725210.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
spindle assembly involved in mitosisGO:009030710.015
dorsal aorta morphogenesisGO:003591230.015
stem cell differentiationGO:00488631170.015
chemosensory behaviorGO:000763510.015
single organism nuclear importGO:190259330.014
endocardial cushion morphogenesisGO:000320330.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
regulation of purine nucleotide catabolic processGO:003312120.014
cleavage furrow formationGO:003608920.014
somite developmentGO:0061053960.014
negative regulation of macromolecule biosynthetic processGO:0010558480.014
ion transportGO:00068111140.014
mitotic cell cycle phase transitionGO:004477290.014
dna catabolic processGO:000630810.014
regulation of carbohydrate metabolic processGO:000610940.014
negative regulation of mapk cascadeGO:004340940.014
pronephros developmentGO:0048793690.014
negative regulation of nucleic acid templated transcriptionGO:1903507450.014
camera type eye developmentGO:00430102220.014
convergent extensionGO:00600261180.014
transition metal ion transportGO:000004160.014
retina development in camera type eyeGO:00600411460.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
positive regulation of wound healingGO:009030310.014
regulation of cell developmentGO:00602841000.014
regulation of cell activationGO:005086510.014
immune system developmentGO:00025201910.014
response to woundingGO:00096111160.014
negative regulation of cellular metabolic processGO:0031324770.014
internal peptidyl lysine acetylationGO:001839320.014
cellular component movementGO:00069283350.014
regulation of filopodium assemblyGO:005148920.014
regulation of protein complex assemblyGO:004325430.013
regulation of synaptic plasticityGO:004816710.013
reactive oxygen species metabolic processGO:007259360.013
regulation of cell substrate adhesionGO:001081010.013
guanosine containing compound catabolic processGO:190106920.013
negative regulation of dna replicationGO:000815620.013
central nervous system neuron developmentGO:0021954290.013
regulation of nucleoside metabolic processGO:000911820.013
regulation of cell cycle phase transitionGO:190198780.013
wnt signaling pathwayGO:0016055800.013
sprouting angiogenesisGO:0002040530.013
cell cycle processGO:0022402530.013
Mouse
regulation of cell communicationGO:00106462320.013
atrioventricular valve formationGO:000319030.013
positive regulation of nucleoside metabolic processGO:004597910.013
response to oxygen containing compoundGO:1901700550.013
energy reserve metabolic processGO:000611220.013
urogenital system developmentGO:0001655970.013
myeloid cell differentiationGO:0030099860.013
microtubule organizing center organizationGO:003102310.013
renal system developmentGO:0072001940.013
gtp metabolic processGO:004603940.013
cell projection organizationGO:00300302840.012
pronephric nephron developmentGO:0039019140.012
regulation of anatomical structure morphogenesisGO:00226031300.012
positive regulation of nucleotide catabolic processGO:003081310.012
striated muscle cell developmentGO:00550021080.012
spermatid differentiationGO:004851520.012
regulation of cellular amine metabolic processGO:003323800.012
negative regulation of signal transductionGO:0009968940.012
histone modificationGO:0016570200.012
embryonic digestive tract morphogenesisGO:004855730.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
cell cycle arrestGO:000705010.012
macromolecular complex subunit organizationGO:0043933740.012
negative regulation of ras protein signal transductionGO:004658010.012
response to bacteriumGO:0009617580.012
regulation of cell matrix adhesionGO:000195210.012
inorganic cation transmembrane transportGO:0098662500.012
female meiosis chromosome segregationGO:001632110.012
positive regulation of neuron apoptotic processGO:004352510.012
agingGO:000756820.012
inorganic ion transmembrane transportGO:0098660570.012
actin cytoskeleton organizationGO:0030036630.011
positive regulation of response to stimulusGO:0048584800.011
forebrain cell migrationGO:002188510.011
positive regulation of muscle organ developmentGO:004863610.011
cell matrix adhesionGO:000716040.011
regulation of chromosome segregationGO:005198310.011
establishment of organelle localizationGO:0051656450.011
cell agingGO:000756920.011
behaviorGO:0007610740.011
regulation of developmental growthGO:0048638380.011
homeostasis of number of cellsGO:0048872620.011
cell adhesionGO:0007155400.011
pronephric glomerulus developmentGO:0039021130.011
regulation of cellular ketone metabolic processGO:001056570.011
regulation of catalytic activityGO:0050790550.011
zymogen activationGO:003163830.011
negative regulation of bmp signaling pathwayGO:0030514130.011
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.011
small gtpase mediated signal transductionGO:000726480.011
spindle assemblyGO:005122520.011
localization of cellGO:00516742440.011
regulation of axonogenesisGO:0050770320.011
negative regulation of synapse assemblyGO:005196420.011
positive regulation of cytoskeleton organizationGO:005149530.011
cell proliferationGO:0008283800.011
cytokinetic processGO:003250620.011
centrosome cycleGO:000709810.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
bmp signaling pathwayGO:0030509520.011
cellular protein modification processGO:00064641000.011
cell projection assemblyGO:0030031640.011
cytokinesisGO:000091030.010
regulation of establishment of planar polarityGO:009017540.010
methylationGO:0032259220.010
negative regulation of rna metabolic processGO:0051253480.010
actin filament based movementGO:003004810.010
peptide metabolic processGO:000651810.010
actin filament organizationGO:0007015150.010
regulation of response to oxidative stressGO:190288220.010
protein dephosphorylationGO:000647030.010
covalent chromatin modificationGO:0016569200.010
cell cycle g2 m phase transitionGO:004483940.010
reciprocal dna recombinationGO:003582510.010
cellular respirationGO:004533330.010

fancd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.139
Human
hematopoietic system diseaseDOID:7400.139
Human
disease of anatomical entityDOID:700.139
Human
muscle tissue diseaseDOID:6600.039
musculoskeletal system diseaseDOID:1700.039
myopathyDOID:42300.039
muscular diseaseDOID:008000000.039
nervous system diseaseDOID:86300.018
bone marrow diseaseDOID:496100.015
Human
disease of cellular proliferationDOID:1456600.014
cardiovascular system diseaseDOID:128700.013
intrinsic cardiomyopathyDOID:006003600.013
cardiomyopathyDOID:005070000.013
heart diseaseDOID:11400.013
colon carcinomaDOID:152000.012
colorectal cancerDOID:925600.012
organ system cancerDOID:005068600.012
gastrointestinal system cancerDOID:311900.012
large intestine cancerDOID:567200.012
cancerDOID:16200.012
intestinal cancerDOID:1015500.012
colon cancerDOID:21900.012