Danio rerio

0 known processes

cfl1

cofilin 1 (non-muscle)

(Aliases: wu:fb18a04,cb86,wu:fk77b03,sb:cb86,zgc:56501)

cfl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin filament polymerizationGO:003004120.347
actin polymerization or depolymerizationGO:000815420.213
Mouse
multicellular organismal water homeostasisGO:005089110.200
morphogenesis of an epitheliumGO:00020093330.200
organelle organizationGO:00069962270.165
Mouse
cellular component biogenesisGO:00440851780.153
regulation of water loss via skinGO:003356110.149
positive regulation of cellular component biogenesisGO:004408930.143
phagocytosisGO:000690930.141
agingGO:000756820.136
cellular component assemblyGO:00226071700.130
regulation of cell matrix adhesionGO:000195210.117
vasculature developmentGO:00019442780.106
positive regulation of transportGO:005105020.101
stem cell maintenanceGO:001982740.099
single organism localizationGO:19025782250.081
transportGO:00068102200.081
negative regulation of protein transportGO:005122430.081
establishment of localizationGO:00512342440.075
response to external biotic stimulusGO:0043207970.073
regulation of defense response to virus by hostGO:005069110.069
positive regulation of defense response to virus by hostGO:000223000.069
positive regulation of protein complex assemblyGO:003133420.067
keratinocyte differentiationGO:003021600.067
glomerulus developmentGO:0032835270.064
single organism transportGO:00447652060.064
alpha amino acid metabolic processGO:190160530.062
cognitionGO:005089010.058
single organism membrane organizationGO:0044802200.058
determination of bilateral symmetryGO:00098552040.058
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.057
single organism organelle organizationGO:19025891990.057
Mouse
establishment of skin barrierGO:006143610.055
membrane fusionGO:006102520.052
water homeostasisGO:003010440.051
positive regulation of protein polymerizationGO:003227320.051
single organism membrane fusionGO:004480120.051
extrinsic apoptotic signaling pathwayGO:009719130.051
tube morphogenesisGO:00352393490.051
maintenance of locationGO:005123540.048
regulation of establishment of protein localizationGO:007020140.046
intestinal absorptionGO:005089220.046
actin cytoskeleton organizationGO:0030036630.045
Mouse
sensory organ developmentGO:00074233930.044
membrane invaginationGO:001032410.044
muscle structure developmentGO:00610611960.043
urea transmembrane transportGO:007191890.042
cellular protein metabolic processGO:00442671290.041
s adenosylmethionine metabolic processGO:004650010.040
negative regulation of defense responseGO:003134820.040
oxoacid metabolic processGO:0043436310.040
organic hydroxy compound transportGO:0015850140.040
digestive tract developmentGO:00485652650.039
protein polymerizationGO:005125840.038
ion transportGO:00068111140.038
cellular component assembly involved in morphogenesisGO:00109271070.037
regulation of ion transmembrane transporter activityGO:003241220.037
organic substance biosynthetic processGO:19015762890.036
regulation of protein import into nucleusGO:004230620.035
single organism metabolic processGO:00447102170.034
protein secretionGO:000930610.034
establishment of protein localization to organelleGO:007259440.033
cytoplasm organizationGO:000702840.033
actin filament based processGO:0030029640.033
Mouse
adherens junction organizationGO:003433240.033
lipid digestionGO:004424130.032
regulation of protein complex assemblyGO:004325430.032
positive regulation of cytoskeleton organizationGO:005149530.031
Mouse
response to organic substanceGO:00100331530.031
regulation of protein localization to nucleusGO:190018020.031
regulation of protein transportGO:005122330.029
localization of cellGO:00516742440.029
regulation of protein polymerizationGO:003227120.029
cellular modified amino acid metabolic processGO:000657530.029
protein heterooligomerizationGO:005129110.029
positive regulation of cell adhesionGO:004578510.028
activation of immune responseGO:000225390.028
gastrulationGO:00073692080.028
immune system processGO:00023762410.027
protein complex subunit organizationGO:0071822460.026
Mouse
convergent extensionGO:00600261180.026
regulation of cytoplasmic transportGO:190364940.026
positive regulation of cytosolic calcium ion concentrationGO:000720440.026
protein importGO:001703830.025
regulation of cytokine productionGO:000181730.025
cellular component morphogenesisGO:00329893360.025
regulation of epidermis developmentGO:004568220.024
skin developmentGO:0043588540.024
actomyosin structure organizationGO:0031032530.024
regulation of response to stimulusGO:00485832690.024
blood vessel morphogenesisGO:00485142160.024
cellular protein modification processGO:00064641000.024
cellular localizationGO:0051641970.023
kidney developmentGO:0001822920.023
regulation of molecular functionGO:0065009700.023
deathGO:00162651210.023
response to acid chemicalGO:0001101170.023
wound healingGO:0042060900.023
response to chemicalGO:00422213200.023
regulation of inflammatory responseGO:005072720.023
negative regulation of nuclear divisionGO:005178430.023
regulation of biological qualityGO:00650082630.022
Mouse
regulation of epithelial cell proliferationGO:005067830.022
protein localization to plasma membraneGO:007265910.022
epithelial cell differentiationGO:00308551160.022
extracellular structure organizationGO:0043062270.022
response to other organismGO:0051707970.022
negative regulation of cytokine productionGO:000181810.022
single organism biosynthetic processGO:0044711710.021
organic acid metabolic processGO:0006082310.021
protein import into nucleusGO:000660630.021
protein metabolic processGO:00195381830.021
autophagyGO:000691440.021
signal transductionGO:00071654550.021
synaptic vesicle transportGO:004848910.021
stem cell developmentGO:0048864820.021
cellular response to chemical stimulusGO:00708871570.020
urogenital system developmentGO:0001655970.020
phagocytosis engulfmentGO:000691110.020
regulation of cellular component organizationGO:0051128860.020
Mouse
regulation of cell differentiationGO:00455951420.020
negative regulation of mitosisGO:004583930.019
response to stressGO:00069502630.019
fatty acid biosynthetic processGO:000663340.019
organonitrogen compound metabolic processGO:1901564740.019
guanosine containing compound catabolic processGO:190106920.019
negative regulation of biological processGO:00485193040.019
metal ion transportGO:0030001580.019
regenerationGO:0031099910.019
cell substrate junction assemblyGO:000704420.019
regulation of metabolic processGO:00192223590.018
regulation of cell activationGO:005086510.018
macromolecular complex assemblyGO:0065003350.018
negative regulation of stem cell differentiationGO:200073720.018
vesicle organizationGO:001605060.018
establishment of protein localization to plasma membraneGO:009000210.018
regulation of organelle organizationGO:0033043290.018
Mouse
cell junction organizationGO:0034330110.018
cellular macromolecule metabolic processGO:00442603910.018
multi organism processGO:00517041340.018
zymogen activationGO:003163830.018
lipid storageGO:001991510.018
apoptotic processGO:00069151160.017
neuron neuron synaptic transmissionGO:000727010.017
nephron developmentGO:0072006310.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
muscle cell differentiationGO:00426921390.017
blood vessel developmentGO:00015682460.017
regulation of actin cytoskeleton organizationGO:003295680.017
Mouse
kidney epithelium developmentGO:0072073230.017
negative regulation of epithelial cell proliferationGO:005068010.017
response to oxygen containing compoundGO:1901700550.017
digestive system developmentGO:00551232890.017
plasma membrane repairGO:000177820.017
membrane raft organizationGO:003157910.016
negative regulation of cellular processGO:00485232830.016
regulation of metal ion transportGO:001095940.016
membrane organizationGO:0061024210.016
cell substrate adhesionGO:003158940.016
negative regulation of wound healingGO:006104510.016
regulation of macromolecule metabolic processGO:00602553170.016
regulation of protein targetingGO:190353320.016
protein modification processGO:00362111000.016
regulation of cytoskeleton organizationGO:0051493110.016
Mouse
regulation of wound healingGO:006104120.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
protein complex assemblyGO:0006461300.016
regulation of bindingGO:005109830.016
energy reserve metabolic processGO:000611220.016
neuroblast fate commitmentGO:001401710.016
small molecule metabolic processGO:0044281770.016
cell morphogenesisGO:00009022890.015
regulation of cellular ketone metabolic processGO:001056570.015
cytosolic calcium ion transportGO:006040130.015
regulation of nucleocytoplasmic transportGO:004682220.015
synaptic vesicle localizationGO:009747910.015
regulation of locomotionGO:0040012550.015
heart field specificationGO:000312810.015
negative regulation of secretionGO:005104820.015
cellular nitrogen compound metabolic processGO:00346412900.015
regulation of gtpase activityGO:004308720.015
cell deathGO:00082191210.015
vesicle mediated transportGO:0016192220.015
cellular amine metabolic processGO:004410620.015
nuclear transportGO:005116940.015
positive regulation of gtp catabolic processGO:003312610.014
response to amino acidGO:004320020.014
positive regulation of catabolic processGO:000989640.014
extracellular matrix organizationGO:0030198270.014
nitrogen compound metabolic processGO:00068073190.014
regulation of intracellular protein transportGO:003315730.014
renal system developmentGO:0072001940.014
macromolecular complex subunit organizationGO:0043933740.014
Mouse
regulation of i kappab kinase nf kappab signalingGO:004312240.014
proximal distal pattern formationGO:000995410.014
amine metabolic processGO:000930820.014
sensory system developmentGO:0048880760.014
epiboly involved in gastrulation with mouth forming secondGO:0055113350.014
developmental growthGO:00485891660.013
positive regulation of biological processGO:00485182530.013
Mouse
positive regulation of cell substrate adhesionGO:001081110.013
hatchingGO:003518840.013
embryo development ending in birth or egg hatchingGO:00097922710.013
epithelial tube morphogenesisGO:00605621480.013
positive regulation of cell cycleGO:004578730.013
axis elongation involved in somitogenesisGO:009024520.013
dorsal ventral pattern formationGO:00099531250.013
protein processingGO:0016485120.013
regulation of multicellular organismal processGO:00512392770.013
positive regulation of molecular functionGO:0044093330.013
regulation of localizationGO:00328791040.013
defense response to fungusGO:005083220.013
cellular amino acid metabolic processGO:000652070.013
cell motilityGO:00488702440.013
programmed cell deathGO:00125011190.013
nuclear importGO:005117030.012
regulation of immune responseGO:0050776140.012
lateral line system developmentGO:0048925760.012
striated muscle cell differentiationGO:00511461290.012
defense responseGO:0006952470.012
regulation of circadian rhythmGO:004275240.012
positive regulation of secretion by cellGO:190353210.012
intestinal cholesterol absorptionGO:003029920.012
regulation of epithelial to mesenchymal transitionGO:001071730.012
epithelial cell morphogenesisGO:000338220.012
organic acid transportGO:001584990.012
tissue regenerationGO:0042246740.012
lipid catabolic processGO:001604240.012
specification of organ identityGO:001009220.012
cellular protein complex assemblyGO:0043623190.012
organelle assemblyGO:00709251100.012
release of sequestered calcium ion into cytosolGO:005120930.012
epidermal cell differentiationGO:0009913360.012
covalent chromatin modificationGO:0016569200.012
regulation of purine nucleotide catabolic processGO:003312120.012
epidermis developmentGO:0008544480.012
system processGO:00030081850.012
negative regulation of kinase activityGO:003367340.012
positive regulation of cellular metabolic processGO:0031325940.012
chromosome organizationGO:0051276310.011
positive regulation of cellular processGO:00485222010.011
Mouse
negative regulation of response to stimulusGO:00485851040.011
fin regenerationGO:0031101510.011
t cell differentiationGO:003021760.011
negative regulation of sequestering of calcium ionGO:005128340.011
regulation of developmental processGO:00507932470.011
cation transportGO:0006812810.011
muscle cell developmentGO:00550011150.011
positive regulation of ras protein signal transductionGO:004657910.011
gtp catabolic processGO:000618420.011
immune system developmentGO:00025201910.011
long chain fatty acid biosynthetic processGO:004275910.011
ion transmembrane transportGO:0034220910.011
positive regulation of cell matrix adhesionGO:000195410.011
meiotic nuclear divisionGO:000712640.011
single organism cellular localizationGO:1902580460.011
nucleocytoplasmic transportGO:000691340.011
regulation of immune system processGO:0002682340.011
protein targeting to nucleusGO:004474430.011
rho protein signal transductionGO:000726650.011
desmosome assemblyGO:000215920.011
innate immune responseGO:0045087130.011
macromolecule modificationGO:00434121110.011
digestive tract morphogenesisGO:00485462310.011
regulation of programmed cell deathGO:00430671010.011
epithelial cell developmentGO:0002064420.011
positive regulation of metabolic processGO:00098931080.011
regulation of filopodium assemblyGO:005148920.011
cellular response to external stimulusGO:007149620.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
monoamine transportGO:001584410.010
cytoskeleton organizationGO:0007010960.010
Mouse
regulation of cell substrate adhesionGO:001081010.010
protein localization to nucleusGO:003450430.010
atrioventricular valve developmentGO:0003171110.010
regulation of biosynthetic processGO:00098892500.010
cortical cytoskeleton organizationGO:003086510.010
regulation of cellular metabolic processGO:00313233200.010
defense response to other organismGO:0098542330.010
cardiac cell fate commitmentGO:006091110.010
regulation of eye photoreceptor cell developmentGO:004247820.010
regulation of mesenchymal cell proliferationGO:001046410.010
kidney vasculature morphogenesisGO:006143910.010

cfl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
integumentary system diseaseDOID:1600.064
disease of anatomical entityDOID:700.064
amyloidosisDOID:912000.016
acquired metabolic diseaseDOID:006015800.016
disease of metabolismDOID:001466700.016
myopathyDOID:42300.012
heart diseaseDOID:11400.012
cardiomyopathyDOID:005070000.012
muscle tissue diseaseDOID:6600.012
cardiovascular system diseaseDOID:128700.012
muscular diseaseDOID:008000000.012
musculoskeletal system diseaseDOID:1700.012