Danio rerio

0 known processes

ddb2

damage-specific DNA binding protein 2

(Aliases: si:dkey-45f10.3)

ddb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
entrainment of circadian clockGO:000964920.642
response to stressGO:00069502630.637
Human Mouse
heterocycle metabolic processGO:00464832900.605
Human Mouse
response to abiotic stimulusGO:00096281220.545
Human
response to radiationGO:0009314510.486
Human
organic cyclic compound metabolic processGO:19013603010.474
Human Mouse
nitrogen compound metabolic processGO:00068073190.459
Human Mouse
nucleic acid metabolic processGO:00903042440.393
Human Mouse
cellular macromolecule metabolic processGO:00442603910.372
Human Mouse
regulation of nitrogen compound metabolic processGO:00511712510.359
regulation of circadian rhythmGO:004275240.339
single organism metabolic processGO:00447102170.327
Human Mouse
negative regulation of biological processGO:00485193040.307
cellular nitrogen compound metabolic processGO:00346412900.290
Human Mouse
cellular aromatic compound metabolic processGO:00067252950.277
Human Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.277
nucleobase containing compound metabolic processGO:00061392740.273
Human Mouse
larval developmentGO:000216420.269
steroid hormone secretionGO:003592910.253
dna metabolic processGO:0006259270.251
Human Mouse
regulation of macromolecule metabolic processGO:00602553170.236
aromatic compound biosynthetic processGO:00194382170.235
regulation of gene expressionGO:00104682650.231
negative regulation of steroid hormone secretionGO:200083210.219
regulation of nucleobase containing compound metabolic processGO:00192192500.217
regulation of macromolecule biosynthetic processGO:00105562250.210
macromolecule biosynthetic processGO:00090592270.199
biosynthetic processGO:00090582940.187
response to external stimulusGO:00096052640.187
intra s dna damage checkpointGO:003157310.185
rna biosynthetic processGO:00327741810.179
regulation of cellular biosynthetic processGO:00313262450.168
regulation of protein ubiquitinationGO:003139630.168
gene expressionGO:00104672520.164
regulation of metabolic processGO:00192223590.163
response to inorganic substanceGO:0010035380.155
mitotic dna integrity checkpointGO:004477440.154
regulation of multicellular organismal processGO:00512392770.151
regulation of rna biosynthetic processGO:20011412130.144
cellular macromolecule biosynthetic processGO:00346452240.144
regulation of transcription dna templatedGO:00063552130.138
regulation of cellular metabolic processGO:00313233200.128
nucleobase containing compound biosynthetic processGO:00346542050.126
heterocycle biosynthetic processGO:00181302150.123
mitotic dna damage checkpointGO:004477340.119
negative regulation of cellular processGO:00485232830.116
response to nutrientGO:000758430.116
response to oxidative stressGO:0006979110.114
transcription dna templatedGO:00063511810.114
regulation of rna metabolic processGO:00512522240.112
maintenance of locationGO:005123540.112
response to reactive oxygen speciesGO:000030250.109
cell cycleGO:0007049930.106
response to hydrogen peroxideGO:004254230.105
rna metabolic processGO:00160702190.104
regulation of biosynthetic processGO:00098892500.103
regulation of tube sizeGO:003515020.101
circadian regulation of gene expressionGO:003292280.095
entrainment of circadian clock by photoperiodGO:004315310.092
signal transductionGO:00071654550.091
endocrine processGO:005088620.091
regulation of nucleic acid templated transcriptionGO:19035062130.090
cellular response to dna damage stimulusGO:0006974240.087
Human Mouse
nucleic acid templated transcriptionGO:00976591810.087
cellular biosynthetic processGO:00442492860.083
generation of neuronsGO:00486993850.081
regulation of endocrine processGO:004406020.080
response to chemicalGO:00422213200.078
organic cyclic compound biosynthetic processGO:19013622230.074
regulation of cell cycleGO:0051726520.073
regulation of primary metabolic processGO:00800903110.071
cellular nitrogen compound biosynthetic processGO:00442712180.066
determination of bilateral symmetryGO:00098552040.064
hormone transportGO:000991420.063
organic substance biosynthetic processGO:19015762890.061
multicellular organism growthGO:003526440.061
dna repairGO:000628160.060
Human Mouse
response to external biotic stimulusGO:0043207970.060
positive regulation of biological processGO:00485182530.059
protein localization to nucleusGO:003450430.059
nuclear transportGO:005116940.057
guanosine containing compound metabolic processGO:190106840.056
regulation of hormone secretionGO:004688320.055
peptidyl serine phosphorylationGO:001810510.054
circadian rhythmGO:0007623190.053
negative regulation of hormone secretionGO:004688820.053
g protein coupled receptor signaling pathwayGO:0007186740.051
agingGO:000756820.050
regulation of multicellular organism growthGO:004001440.050
glucose homeostasisGO:004259310.050
blood vessel morphogenesisGO:00485142160.048
cell cycle checkpointGO:000007570.048
positive regulation of cellular metabolic processGO:0031325940.047
regulation of protein modification by small protein conjugation or removalGO:190332030.046
hormone secretionGO:004687920.045
protein targeting to nucleusGO:004474430.045
eye developmentGO:00016542770.045
cellular response to stressGO:0033554620.045
Human Mouse
protein import into nucleusGO:000660630.045
immune system processGO:00023762410.045
camera type eye developmentGO:00430102220.044
regulation of protein transportGO:005122330.044
carbohydrate homeostasisGO:003350010.044
negative regulation of transcription dna templatedGO:0045892450.043
regulation of biological qualityGO:00650082630.041
blood vessel developmentGO:00015682460.039
negative regulation of gene expressionGO:0010629650.039
negative regulation of macromolecule metabolic processGO:0010605760.039
neuron differentiationGO:00301823530.038
peptidyl serine modificationGO:001820920.037
cell substrate adhesionGO:003158940.037
central nervous system developmentGO:00074173870.037
gtp metabolic processGO:004603940.037
system processGO:00030081850.036
single organism organelle organizationGO:19025891990.035
Human
homeostatic processGO:00425921420.035
regulation of transcription from rna polymerase ii promoterGO:00063571140.035
negative regulation of secretionGO:005104820.034
regulation of nucleocytoplasmic transportGO:004682220.034
establishment of protein localization to organelleGO:007259440.034
nucleocytoplasmic transportGO:000691340.034
negative regulation of nitrogen compound metabolic processGO:0051172590.033
response to uvGO:000941130.033
Human
positive regulation of cell cycleGO:004578730.033
negative regulation of nucleobase containing compound metabolic processGO:0045934590.033
mitotic cell cycle processGO:1903047480.033
growthGO:00400071740.032
neurotransmitter transportGO:000683620.032
negative regulation of mitotic cell cycle phase transitionGO:190199150.032
rhythmic processGO:0048511210.030
regulation of reproductive processGO:200024140.030
cell surface receptor signaling pathwayGO:00071663250.030
response to drugGO:004249330.030
multi organism processGO:00517041340.030
negative regulation of biosynthetic processGO:0009890550.030
regulation of blood pressureGO:000821710.029
single organism nuclear importGO:190259330.029
negative regulation of macromolecule biosynthetic processGO:0010558480.029
regulation of blood vessel sizeGO:005088020.028
regulation of neurotransmitter transportGO:005158810.028
establishment of localizationGO:00512342440.028
regulation of bindingGO:005109830.028
cellular ketone metabolic processGO:0042180110.028
negative regulation of cellular biosynthetic processGO:0031327550.028
negative regulation of nucleic acid templated transcriptionGO:1903507450.028
regulation of intracellular protein transportGO:003315730.027
vasculature developmentGO:00019442780.027
regulation of steroid hormone secretionGO:200083110.027
regulation of cell shapeGO:000836010.027
endocrine hormone secretionGO:006098620.027
nuclear importGO:005117030.026
transcription from rna polymerase ii promoterGO:0006366800.026
lipid storageGO:001991510.026
gtp catabolic processGO:000618420.026
negative regulation of secretion by cellGO:190353120.026
negative regulation of cellular metabolic processGO:0031324770.025
regulation of cell deathGO:00109411030.025
dna damage checkpointGO:000007760.024
positive regulation of nitrogen compound metabolic processGO:0051173690.024
positive regulation of rna biosynthetic processGO:1902680570.024
regulation of establishment of protein localizationGO:007020140.024
regulation of developmental processGO:00507932470.024
rna localizationGO:000640340.023
transportGO:00068102200.023
regulation of protein targetingGO:190353320.023
regulation of mitotic cell cycleGO:0007346250.023
protein importGO:001703830.023
regulation of response to stimulusGO:00485832690.023
negative regulation of response to stimulusGO:00485851040.023
positive regulation of cellular processGO:00485222010.022
positive regulation of cellular biosynthetic processGO:0031328680.022
positive regulation of transcription dna templatedGO:0045893570.022
regulation of cell cycle phase transitionGO:190198780.022
regulation of cytoplasmic transportGO:190364940.022
negative regulation of mitosisGO:004583930.021
amine metabolic processGO:000930820.021
adult behaviorGO:003053420.021
heart developmentGO:00075073130.021
response to oxygen containing compoundGO:1901700550.021
cell projection organizationGO:00300302840.021
peptide transportGO:001583310.021
negative regulation of cell communicationGO:0010648960.021
regulation of protein complex assemblyGO:004325430.020
regulation of cell activationGO:005086510.020
response to corticosteroidGO:003196010.020
cellular response to decreased oxygen levelsGO:003629410.020
regulation of localizationGO:00328791040.020
regulation of cytokine productionGO:000181730.020
positive regulation of macromolecule metabolic processGO:0010604930.020
regulation of cellular ketone metabolic processGO:001056570.020
cellular component morphogenesisGO:00329893360.020
cellular protein metabolic processGO:00442671290.020
Human
regulation of signalingGO:00230512350.020
dna integrity checkpointGO:003157060.019
positive regulation of secretionGO:005104710.019
response to biotic stimulusGO:0009607970.019
locomotor rhythmGO:004547530.019
amino acid transportGO:000686520.019
cellular response to extracellular stimulusGO:003166820.019
programmed cell deathGO:00125011190.019
regulation of signal transductionGO:00099662250.019
regulation of hormone levelsGO:0010817210.019
negative regulation of rna biosynthetic processGO:1902679450.019
cell projection morphogenesisGO:00488582440.019
regulation of purine nucleotide catabolic processGO:003312120.019
cell morphogenesisGO:00009022890.019
covalent chromatin modificationGO:0016569200.019
Human
ribonucleoside monophosphate catabolic processGO:000915840.019
circulatory system processGO:0003013870.019
circadian sleep wake cycleGO:004274520.019
apoptotic processGO:00069151160.019
negative regulation of rna metabolic processGO:0051253480.019
guanosine containing compound catabolic processGO:190106920.019
regulation of dna replicationGO:000627530.019
specification of symmetryGO:00097992040.018
apical junction assemblyGO:004329710.018
response to temperature stimulusGO:0009266150.018
proteolysis involved in cellular protein catabolic processGO:005160330.018
response to ketoneGO:190165410.018
regulation of protein localization to nucleusGO:190018020.018
cellular carbohydrate metabolic processGO:004426240.018
mitochondrion organizationGO:000700540.018
positive regulation of secretion by cellGO:190353210.018
response to other organismGO:0051707970.018
negative regulation of metabolic processGO:0009892860.018
positive regulation of catabolic processGO:000989640.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
regulation of nucleotide catabolic processGO:003081120.017
response to alkaloidGO:004327920.017
positive regulation of nucleobase containing compound metabolic processGO:0045935690.017
neuron developmentGO:00486662620.017
cellular response to hypoxiaGO:007145610.017
regulation of cell communicationGO:00106462320.017
synaptic growth at neuromuscular junctionGO:005112420.017
atp catabolic processGO:000620040.017
regulation of nucleoside metabolic processGO:000911820.017
cell deathGO:00082191210.017
muscle organ developmentGO:00075171010.017
cellular component disassemblyGO:002241110.017
regulation of programmed cell deathGO:00430671010.017
cellular protein catabolic processGO:004425740.017
regulation of mitotic cell cycle phase transitionGO:190199080.017
cellular response to oxygen levelsGO:007145310.017
regulation of circadian sleep wake cycle sleepGO:004518710.017
mitotic cell cycleGO:0000278640.017
regulation of protein catabolic processGO:004217610.017
antimicrobial humoral responseGO:001973020.016
regulation of circadian sleep wake cycleGO:004274910.016
cellular response to radiationGO:007147840.016
Human
autophagyGO:000691440.016
positive regulation of metabolic processGO:00098931080.016
modification dependent macromolecule catabolic processGO:004363230.016
stem cell maintenanceGO:001982740.016
circadian sleep wake cycle sleepGO:005080210.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.016
regulation of cellular amino acid metabolic processGO:000652100.016
negative regulation of protein phosphorylationGO:000193340.016
cellular response to starvationGO:000926710.016
positive regulation of transportGO:005105020.016
female sex differentiationGO:004666040.016
deathGO:00162651210.016
locomotionGO:00400113130.016
sprouting angiogenesisGO:0002040530.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
organic acid metabolic processGO:0006082310.016
response to monosaccharideGO:003428430.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.016
regulation of synapse assemblyGO:005196330.016
regulation of meiotic cell cycleGO:005144510.016
response to amineGO:001407510.016
response to organic substanceGO:00100331530.016
regulation of myotube differentiationGO:001083020.015
peptidyl lysine acetylationGO:001839420.015
regulation of metal ion transportGO:001095940.015
positive regulation of cellular catabolic processGO:003133130.015
tissue remodelingGO:004877140.015
meiotic nuclear divisionGO:000712640.015
negative regulation of protein localization to nucleusGO:190018120.015
photoperiodismGO:0009648110.015
regulation of neurotransmitter secretionGO:004692810.015
meiotic chromosome segregationGO:004513230.015
organelle organizationGO:00069962270.015
Human
regulation of synapse organizationGO:005080730.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
regulation of skeletal muscle tissue developmentGO:004864140.015
lipid homeostasisGO:005508830.015
ubiquitin dependent protein catabolic processGO:000651130.015
lipid catabolic processGO:001604240.015
cellular response to external stimulusGO:007149620.015
regulation of protein import into nucleusGO:004230620.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
cellular amine metabolic processGO:004410620.015
determination of left right asymmetry in lateral mesodermGO:0003140200.015
protein complex disassemblyGO:004324110.014
fertilizationGO:000956630.014
response to amphetamineGO:000197510.014
regulation of cell differentiationGO:00455951420.014
response to woundingGO:00096111160.014
oxoacid metabolic processGO:0043436310.014
regulation of inflammatory responseGO:005072720.014
macromolecule modificationGO:00434121110.014
Human
determination of left right symmetryGO:00073681790.014
purine nucleoside monophosphate catabolic processGO:000912840.014
regulation of cellular amine metabolic processGO:003323800.014
developmental growthGO:00485891660.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
negative regulation of protein transportGO:005122430.014
response to hexoseGO:000974630.014
macromolecule localizationGO:0033036540.014
neuron neuron synaptic transmissionGO:000727010.014
response to foodGO:003209410.013
negative regulation of cell cycle phase transitionGO:190198850.013
response to light stimulusGO:0009416460.013
Human
negative regulation of nucleocytoplasmic transportGO:004682320.013
protein stabilizationGO:005082120.013
regulation of cell cycle processGO:0010564200.013
positive regulation of nucleoside metabolic processGO:004597910.013
positive regulation of nucleic acid templated transcriptionGO:1903508570.013
determination of heart left right asymmetryGO:00613711170.013
macromolecular complex disassemblyGO:003298410.013
organ regenerationGO:003110010.013
single fertilizationGO:000733830.013
stem cell proliferationGO:007208940.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
head developmentGO:00603223030.013
exocytosisGO:000688710.013
secondary metabolic processGO:001974830.013
meiotic cell cycle processGO:190304630.013
regulation of transportGO:0051049450.013
ventricular cardiac muscle tissue developmentGO:000322930.013
morphogenesis of an epitheliumGO:00020093330.013
regulation of epithelial cell proliferationGO:005067830.013
negative regulation of signalingGO:0023057960.013
regulation of response to extracellular stimulusGO:003210410.013
lymphocyte proliferationGO:004665110.013
cell morphogenesis involved in differentiationGO:00009041950.013
protein polymerizationGO:005125840.013
response to vitaminGO:003327330.013
phototransductionGO:000760220.013
phagocytosisGO:000690930.013
proteasomal protein catabolic processGO:001049820.013
positive regulation of cytoskeleton organizationGO:005149530.013
regulation of synaptic plasticityGO:004816710.012
carboxylic acid metabolic processGO:0019752220.012
cell matrix adhesionGO:000716040.012
hepaticobiliary system developmentGO:0061008980.012
positive regulation of muscle organ developmentGO:004863610.012
regulation of calcium ion transportGO:005192420.012
circadian sleep wake cycle processGO:002241020.012
leukocyte proliferationGO:007066110.012
positive regulation of cell activationGO:005086710.012
microtubule organizing center organizationGO:003102310.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
tube morphogenesisGO:00352393490.012
b cell mediated immunityGO:001972430.012
chemical homeostasisGO:0048878490.012
astrocyte differentiationGO:004870810.012
collagen metabolic processGO:003296320.012
negative regulation of dna metabolic processGO:005105340.012
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.012
negative regulation of protein import into nucleusGO:004230820.012
regulation of skeletal muscle fiber developmentGO:004874220.012
regulation of cellular protein metabolic processGO:0032268520.012
behaviorGO:0007610740.012
regulation of systemic arterial blood pressureGO:000307310.012
protein acylationGO:004354330.012
sequestering of metal ionGO:005123830.012
mesoderm developmentGO:0007498880.012
regulation of protein complex disassemblyGO:004324410.012
response to glucoseGO:000974930.012
mononuclear cell proliferationGO:003294310.012
toll like receptor signaling pathwayGO:000222440.012
negative regulation of multicellular organismal processGO:0051241690.012
positive regulation of cellular amine metabolic processGO:003324000.012
macroautophagyGO:001623610.011
smooth muscle contractionGO:000693920.011
regulation of response to nutrient levelsGO:003210710.011
single organism biosynthetic processGO:0044711710.011
negative regulation of dna replicationGO:000815620.011
microtubule polymerization or depolymerizationGO:003110930.011
negative regulation of map kinase activityGO:004340720.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
directional locomotionGO:003305810.011
negative regulation of cytoplasmic transportGO:190365020.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
negative regulation of signal transductionGO:0009968940.011
protein metabolic processGO:00195381830.011
Human
internal protein amino acid acetylationGO:000647520.011
cellular response to nutrient levelsGO:003166920.011
meiosis iGO:000712710.011
regulation of gtpase activityGO:004308720.011
regulation of cellular protein catabolic processGO:190336210.011
nuclear exportGO:005116810.011
b cell activationGO:004211320.011
chromatin modificationGO:0016568210.011
Human
ovulation cycle processGO:002260220.011
hemopoiesisGO:00300971830.011
ganglioside metabolic processGO:000157330.011
negative regulation of cellular catabolic processGO:003133030.011
protein homooligomerizationGO:005126030.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
establishment of localization in cellGO:0051649770.011
embryo development ending in birth or egg hatchingGO:00097922710.011
negative regulation of mitotic cell cycleGO:0045930110.011
negative regulation of intracellular protein transportGO:009031730.011
positive regulation of nucleotide catabolic processGO:003081310.011
positive regulation of cytokine productionGO:000181920.011
cellular localizationGO:0051641970.011
single organism membrane fusionGO:004480120.011
negative regulation of catabolic processGO:000989530.011
immunoglobulin mediated immune responseGO:001606430.010
cytoplasm organizationGO:000702840.010
nucleoside monophosphate catabolic processGO:000912540.010
regulation of cardiac muscle tissue developmentGO:005502410.010
pancreas developmentGO:0031016840.010
positive regulation of cell divisionGO:005178120.010
centrosome organizationGO:005129710.010
protein localization to plasma membraneGO:007265910.010
positive regulation of stem cell proliferationGO:200064810.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
development of primary female sexual characteristicsGO:004654540.010
regulation of peptidyl tyrosine phosphorylationGO:005073010.010
cellular amino acid metabolic processGO:000652070.010
regenerationGO:0031099910.010
cell motilityGO:00488702440.010
regulation of canonical wnt signaling pathwayGO:0060828340.010

ddb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
organ system cancerDOID:005068600.022
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
nervous system diseaseDOID:86300.010
musculoskeletal system diseaseDOID:1700.010
muscular diseaseDOID:008000000.010