Danio rerio

56 known processes

tfr1a

transferrin receptor 1a

tfr1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
erythrocyte homeostasisGO:0034101550.996
erythrocyte maturationGO:004324980.995
hemopoiesisGO:00300971830.993
erythrocyte differentiationGO:0030218540.992
immune system developmentGO:00025201910.988
hematopoietic or lymphoid organ developmentGO:00485341910.978
porphyrin containing compound metabolic processGO:0006778100.977
cofactor biosynthetic processGO:0051188100.951
heme metabolic processGO:004216890.946
myeloid cell differentiationGO:0030099860.934
homeostasis of number of cellsGO:0048872620.930
transition metal ion transportGO:000004160.925
Human
hemoglobin biosynthetic processGO:004254180.894
porphyrin containing compound biosynthetic processGO:000677980.881
tetrapyrrole biosynthetic processGO:003301480.853
heme biosynthetic processGO:000678380.848
tetrapyrrole metabolic processGO:0033013100.810
iron ion transportGO:000682640.801
Human
embryonic hemopoiesisGO:0035162530.762
primitive erythrocyte differentiationGO:006031950.754
myeloid cell homeostasisGO:0002262560.726
immune system processGO:00023762410.664
agingGO:000756820.658
cellular biosynthetic processGO:00442492860.657
generation of neuronsGO:00486993850.561
nitrogen compound metabolic processGO:00068073190.559
aromatic compound biosynthetic processGO:00194382170.461
cellular iron ion homeostasisGO:000687930.429
homeostatic processGO:00425921420.420
heterocycle biosynthetic processGO:00181302150.415
heterocycle metabolic processGO:00464832900.400
spindle assemblyGO:005122520.396
regulation of biological qualityGO:00650082630.388
cellular macromolecule biosynthetic processGO:00346452240.366
neuron differentiationGO:00301823530.366
regulation of transcription dna templatedGO:00063552130.364
regulation of macromolecule metabolic processGO:00602553170.363
definitive hemopoiesisGO:0060216180.358
cellular transition metal ion homeostasisGO:004691630.356
embryonic organ developmentGO:00485683810.352
cellular aromatic compound metabolic processGO:00067252950.341
compound eye developmentGO:004874920.339
cellular component morphogenesisGO:00329893360.336
vasculature developmentGO:00019442780.325
positive regulation of i kappab kinase nf kappab signalingGO:004312330.312
gene expressionGO:00104672520.311
cellular nitrogen compound metabolic processGO:00346412900.294
macromolecule biosynthetic processGO:00090592270.285
nucleic acid metabolic processGO:00903042440.276
cellular macromolecule metabolic processGO:00442603910.273
cofactor metabolic processGO:0051186150.271
cell part morphogenesisGO:00329902460.265
pigment biosynthetic processGO:004614890.262
cellular component biogenesisGO:00440851780.256
cell surface receptor signaling pathwayGO:00071663250.252
organic cyclic compound metabolic processGO:19013603010.246
regulation of metabolic processGO:00192223590.243
erythrocyte developmentGO:0048821240.238
convergent extensionGO:00600261180.201
iron ion transmembrane transportGO:003475530.196
protein metabolic processGO:00195381830.193
cell projection morphogenesisGO:00488582440.193
axon developmentGO:00615641660.192
superoxide metabolic processGO:000680120.177
organonitrogen compound biosynthetic processGO:1901566470.177
single organism biosynthetic processGO:0044711710.172
hemoglobin metabolic processGO:0020027120.164
signal transductionGO:00071654550.162
cell projection organizationGO:00300302840.160
spindle assembly involved in mitosisGO:009030710.158
response to external stimulusGO:00096052640.158
osteoclast differentiationGO:003031610.156
Mouse
organic substance biosynthetic processGO:19015762890.152
microtubule cytoskeleton organization involved in mitosisGO:190285010.152
cation homeostasisGO:0055080330.143
larval developmentGO:000216420.137
response to chemicalGO:00422213200.136
neuron developmentGO:00486662620.135
regulation of multicellular organismal developmentGO:20000262230.134
muscle structure developmentGO:00610611960.132
cell morphogenesis involved in differentiationGO:00009041950.130
cation transportGO:0006812810.129
Human
nuclear migrationGO:000709730.129
maturation of ssu rrnaGO:003049010.128
cell morphogenesisGO:00009022890.125
regulation of myelinationGO:003164110.124
organelle assemblyGO:00709251100.121
cellular nitrogen compound biosynthetic processGO:00442712180.117
skeletal system developmentGO:00015011810.116
biosynthetic processGO:00090582940.114
regulation of gene expressionGO:00104682650.111
organic cyclic compound biosynthetic processGO:19013622230.110
heart developmentGO:00075073130.110
organonitrogen compound metabolic processGO:1901564740.109
positive regulation of map kinase activityGO:004340630.109
hematopoietic stem cell differentiationGO:0060218200.107
neuron projection morphogenesisGO:00488121610.105
intracellular transportGO:0046907320.103
programmed cell deathGO:00125011190.102
cellular response to superoxideGO:007145120.101
cellular response to lipopolysaccharideGO:007122230.095
cellular response to molecule of bacterial originGO:007121930.094
cytokinesisGO:000091030.094
cell cycle g2 m phase transitionGO:004483940.093
nucleobase containing compound biosynthetic processGO:00346542050.092
negative regulation of signal transduction in absence of ligandGO:190109910.091
regulation of protein modification by small protein conjugation or removalGO:190332030.090
regulation of protein ubiquitinationGO:003139630.090
cellular protein catabolic processGO:004425740.088
single organism localizationGO:19025782250.088
Human
single organism metabolic processGO:00447102170.087
iron ion homeostasisGO:005507240.085
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.084
metal ion transportGO:0030001580.084
Human
microtubule organizing center organizationGO:003102310.083
macromolecular complex subunit organizationGO:0043933740.081
modification dependent protein catabolic processGO:001994130.080
regulation of biosynthetic processGO:00098892500.078
chemical homeostasisGO:0048878490.077
cellular response to external stimulusGO:007149620.073
response to stressGO:00069502630.073
rna biosynthetic processGO:00327741810.073
response to transition metal nanoparticleGO:1990267280.073
cellular component assemblyGO:00226071700.073
cell morphogenesis involved in neuron differentiationGO:00486671630.072
nuclear importGO:005117030.071
i kappab kinase nf kappab signalingGO:000724940.071
regulation of rna metabolic processGO:00512522240.071
establishment of localizationGO:00512342440.070
Human
regulation of multicellular organismal processGO:00512392770.070
Mouse
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.070
regulation of cell differentiationGO:00455951420.070
translational initiationGO:000641330.069
liver developmentGO:0001889960.068
extrinsic apoptotic signaling pathwayGO:009719130.067
stem cell proliferationGO:007208940.067
epithelial tube morphogenesisGO:00605621480.067
axonogenesisGO:00074091520.067
small molecule metabolic processGO:0044281770.066
regulation of cellular metabolic processGO:00313233200.066
inorganic ion transmembrane transportGO:0098660570.064
sensory perception of chemical stimulusGO:000760630.063
determination of left right symmetryGO:00073681790.062
cellular cation homeostasisGO:0030003170.062
microtubule depolymerizationGO:000701910.061
response to copper ionGO:0046688130.061
cation transmembrane transportGO:0098655650.060
enzyme linked receptor protein signaling pathwayGO:00071671060.060
biological adhesionGO:0022610400.059
neuron projection guidanceGO:0097485860.059
primitive hemopoiesisGO:0060215270.059
regulation of bindingGO:005109830.058
regulation of cellular macromolecule biosynthetic processGO:20001122220.058
regulation of macromolecule biosynthetic processGO:00105562250.057
regulation of developmental processGO:00507932470.057
proteolysis involved in cellular protein catabolic processGO:005160330.056
cytosolic calcium ion transportGO:006040130.056
regulation of establishment of protein localizationGO:007020140.056
g2 m transition of mitotic cell cycleGO:000008640.055
neuron projection developmentGO:00311751800.055
negative regulation of biological processGO:00485193040.055
regulation of erythrocyte differentiationGO:004564620.055
histone h3 k4 methylationGO:005156820.054
regulation of cytoskeleton organizationGO:0051493110.054
carbohydrate derivative biosynthetic processGO:1901137430.054
regulation of multicellular organism growthGO:004001440.054
regulation of nitrogen compound metabolic processGO:00511712510.054
response to bacteriumGO:0009617580.051
pigment metabolic processGO:0042440120.051
maintenance of locationGO:005123540.051
outflow tract morphogenesisGO:000315110.051
ribosomal small subunit biogenesisGO:004227420.050
cellular metal ion homeostasisGO:0006875160.050
cellular response to lipidGO:0071396390.050
ventricular cardiac muscle tissue developmentGO:000322930.049
nuclear transportGO:005116940.049
response to oxygen radicalGO:000030520.049
heart valve formationGO:000318840.049
response to glucocorticoidGO:005138410.049
regulation of protein import into nucleusGO:004230620.047
regulation of nucleocytoplasmic transportGO:004682220.047
muscle organ developmentGO:00075171010.047
tissue remodelingGO:004877140.047
Mouse
negative regulation of leukocyte differentiationGO:190210610.047
ion homeostasisGO:0050801410.046
cellular ketone metabolic processGO:0042180110.046
modification dependent macromolecule catabolic processGO:004363230.046
negative regulation of metabolic processGO:0009892860.046
negative regulation of cell differentiationGO:0045596460.045
organelle organizationGO:00069962270.045
response to other organismGO:0051707970.045
proteasomal protein catabolic processGO:001049820.045
regulation of cell matrix adhesionGO:000195210.045
response to superoxideGO:000030320.045
neuroblast proliferationGO:000740520.044
gland developmentGO:00487321430.044
cell cycle g1 s phase transitionGO:004484310.043
heart morphogenesisGO:00030071560.043
regulation of extrinsic apoptotic signaling pathwayGO:200123630.043
regulation of dendrite developmentGO:005077330.043
sprouting angiogenesisGO:0002040530.042
developmental growth involved in morphogenesisGO:0060560860.042
transition metal ion homeostasisGO:005507650.042
cardiac muscle tissue developmentGO:0048738480.042
heart loopingGO:0001947940.042
removal of superoxide radicalsGO:001943020.042
toll like receptor signaling pathwayGO:000222440.042
synaptic growth at neuromuscular junctionGO:005112420.041
regulation of response to stimulusGO:00485832690.041
granulocyte differentiationGO:003085180.041
glycoprotein biosynthetic processGO:0009101210.041
mitochondrial transportGO:000683920.040
regulation of cellular biosynthetic processGO:00313262450.040
negative regulation of developmental processGO:0051093650.040
cardiac atrium developmentGO:000323040.039
pharyngeal muscle developmentGO:004328240.038
fin developmentGO:0033333770.038
cell deathGO:00082191210.038
lymphatic endothelial cell differentiationGO:006083610.038
regulation of transcription from rna polymerase ii promoterGO:00063571140.038
regulation of synapse assemblyGO:005196330.038
response to abiotic stimulusGO:00096281220.037
regulation of cell communicationGO:00106462320.037
cellular amine metabolic processGO:004410620.037
blood vessel morphogenesisGO:00485142160.036
protein localization to nucleusGO:003450430.036
regulation of ectoderm developmentGO:200038320.036
regulation of cell developmentGO:00602841000.035
rna metabolic processGO:00160702190.035
microtubule polymerization or depolymerizationGO:003110930.035
protein importGO:001703830.035
regulation of cellular ketone metabolic processGO:001056570.035
reflexGO:006000420.034
activation of mapk activityGO:000018730.034
cellular response to chemical stimulusGO:00708871570.034
protein targeting to nucleusGO:004474430.034
negative regulation of multicellular organismal processGO:0051241690.033
oxoacid metabolic processGO:0043436310.033
embryonic limb morphogenesisGO:003032620.033
single organism transportGO:00447652060.033
Human
regulation of protein bindingGO:004339330.033
cellular response to reactive oxygen speciesGO:003461420.033
regulation of cell deathGO:00109411030.033
mitotic dna integrity checkpointGO:004477440.033
cellular response to biotic stimulusGO:007121630.032
specification of symmetryGO:00097992040.032
protein complex assemblyGO:0006461300.032
protein homooligomerizationGO:005126030.032
convergent extension involved in organogenesisGO:0060029100.031
apoptotic processGO:00069151160.031
multicellular organism growthGO:003526440.031
platelet formationGO:003022010.031
positive regulation of ras protein signal transductionGO:004657910.031
regulation of rna biosynthetic processGO:20011412130.031
organic acid metabolic processGO:0006082310.031
cellular protein metabolic processGO:00442671290.031
protein import into nucleusGO:000660630.031
regulation of synapse organizationGO:005080730.030
protein modification by small protein conjugation or removalGO:0070647140.030
chordate embryonic developmentGO:00430092710.030
macromolecular complex disassemblyGO:003298410.030
developmental growthGO:00485891660.030
negative regulation of macromolecule metabolic processGO:0010605760.030
mitotic g2 m transition checkpointGO:004481830.029
cellular response to starvationGO:000926710.029
cytoskeleton organizationGO:0007010960.029
innate immune response activating signal transductionGO:000275850.028
cellular protein complex disassemblyGO:004362410.028
centrosome cycleGO:000709810.028
regulation of neurogenesisGO:0050767870.028
establishment of localization in cellGO:0051649770.028
regulation of collateral sprouting in absence of injuryGO:004869640.028
mitotic nuclear divisionGO:0007067180.027
morphogenesis of an epitheliumGO:00020093330.027
chemosensory behaviorGO:000763510.027
peptide metabolic processGO:000651810.027
protein localization to plasma membraneGO:007265910.027
regulation of nucleobase containing compound metabolic processGO:00192192500.027
axon guidanceGO:0007411860.027
system processGO:00030081850.027
proepicardium developmentGO:000334240.027
regulation of cellular amino acid metabolic processGO:000652100.027
endosome organizationGO:000703220.026
cellular component movementGO:00069283350.026
regulation of protein targetingGO:190353320.026
negative regulation of sequestering of calcium ionGO:005128340.026
transcription elongation from rna polymerase ii promoterGO:000636830.026
pattern recognition receptor signaling pathwayGO:000222150.026
regulation of anatomical structure morphogenesisGO:00226031300.026
angiogenesisGO:00015251580.026
regulation of cellular amine metabolic processGO:003323800.026
response to drugGO:004249330.025
positive regulation of cellular component biogenesisGO:004408930.025
ion transmembrane transportGO:0034220910.025
cellular localizationGO:0051641970.025
axonal defasciculationGO:000741420.025
ribonucleoside monophosphate catabolic processGO:000915840.024
female meiotic divisionGO:000714320.024
central nervous system developmentGO:00074173870.024
embryonic neurocranium morphogenesisGO:0048702150.024
purine nucleoside monophosphate catabolic processGO:000912840.024
appendage developmentGO:0048736800.024
regulation of signal transductionGO:00099662250.024
negative regulation of cellular processGO:00485232830.024
cortical actin cytoskeleton organizationGO:003086610.024
hepaticobiliary system developmentGO:0061008980.023
cell adhesionGO:0007155400.023
transmembrane transportGO:00550851200.023
positive regulation of gtpase activityGO:004354710.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
embryonic heart tube developmentGO:00350501330.023
regulation of signalingGO:00230512350.023
regulation of protein depolymerizationGO:190187910.023
regulation of cell shapeGO:000836010.023
optic nerve morphogenesisGO:002163160.023
determination of heart left right asymmetryGO:00613711170.023
b cell activationGO:004211320.022
regulation of histone methylationGO:003106030.022
transportGO:00068102200.022
Human
atrioventricular valve formationGO:000319030.022
transcription dna templatedGO:00063511810.022
regulation of programmed cell deathGO:00430671010.022
anatomical structure homeostasisGO:0060249360.022
Mouse
negative regulation of macromolecule biosynthetic processGO:0010558480.022
regulation of protein complex disassemblyGO:004324410.022
cardiac cell fate commitmentGO:006091110.022
sequestering of metal ionGO:005123830.022
establishment of protein localization to organelleGO:007259440.022
cellular protein modification processGO:00064641000.022
cellular response to extracellular stimulusGO:003166820.021
protein depolymerizationGO:005126110.021
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.021
negative regulation of mitosisGO:004583930.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.021
rrna processingGO:000636470.021
protein phosphorylationGO:0006468470.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
heart processGO:0003015710.021
amine metabolic processGO:000930820.021
regulation of cellular component sizeGO:0032535300.021
regulation of circadian rhythmGO:004275240.021
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.021
fertilizationGO:000956630.021
cardiac chamber developmentGO:0003205190.021
positive regulation of cellular amine metabolic processGO:003324000.020
blood vessel developmentGO:00015682460.020
septum transversum developmentGO:000334340.020
intracellular estrogen receptor signaling pathwayGO:003052030.020
lymphocyte proliferationGO:004665110.020
leukocyte proliferationGO:007066110.020
cellular response to retinoic acidGO:007130010.020
macromolecular complex assemblyGO:0065003350.020
regulation of axon extensionGO:0030516240.020
regulation of mitosisGO:000708890.020
protein complex biogenesisGO:0070271300.020
deathGO:00162651210.020
metal ion homeostasisGO:0055065260.020
regulation of sarcomere organizationGO:006029720.020
single fertilizationGO:000733830.020
epithelial cell morphogenesisGO:000338220.020
actin cytoskeleton organizationGO:0030036630.019
response to biotic stimulusGO:0009607970.019
sodium ion transportGO:0006814240.019
cellular component assembly involved in morphogenesisGO:00109271070.019
cellular component disassemblyGO:002241110.019
taxisGO:00423301090.019
locomotory behaviorGO:0007626340.019
leukocyte homeostasisGO:000177620.019
determination of dorsal ventral asymmetryGO:0048262340.019
cytoskeleton dependent cytokinesisGO:006164030.019
single organism nuclear importGO:190259330.019
response to organic substanceGO:00100331530.018
positive regulation of transcription dna templatedGO:0045893570.018
regulation of mitochondrion organizationGO:001082110.018
cardiac ventricle developmentGO:000323190.018
protein complex disassemblyGO:004324110.018
cartilage developmentGO:0051216960.018
olfactory bulb developmentGO:002177240.018
negative regulation of cytokine productionGO:000181810.018
ribosome biogenesisGO:004225490.018
regulation of neuron differentiationGO:0045664560.018
myeloid leukocyte differentiationGO:0002573150.018
Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.018
negative regulation of chromosome organizationGO:200125110.018
cellular amide metabolic processGO:004360340.018
regulation of skeletal muscle fiber developmentGO:004874220.018
protein complex subunit organizationGO:0071822460.018
vascular endothelial growth factor receptor signaling pathwayGO:0048010130.017
single organism intracellular transportGO:1902582250.017
negative regulation of biosynthetic processGO:0009890550.017
regulation of cell sizeGO:0008361290.017
platelet morphogenesisGO:003634410.017
embryo development ending in birth or egg hatchingGO:00097922710.017
muscle tissue developmentGO:00605371100.017
apoptotic signaling pathwayGO:0097190230.017
dna methylation on cytosineGO:003277630.017
striated muscle tissue developmentGO:00147061100.017
calcium ion transport into cytosolGO:006040230.017
protein methylationGO:0006479130.016
nucleic acid templated transcriptionGO:00976591810.016
myofibril assemblyGO:0030239480.016
response to inorganic substanceGO:0010035380.016
regulation of protein localization to nucleusGO:190018020.016
lipid storageGO:001991510.016
cell fate commitmentGO:0045165990.016
response to amphetamineGO:000197510.016
cellular response to organic substanceGO:00713101050.016
intestinal absorptionGO:005089220.016
regulation of heart growthGO:006042020.016
sister chromatid segregationGO:000081960.016
peripheral nervous system developmentGO:0007422550.016
regulation of protein transportGO:005122330.016
ph reductionGO:004585110.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
mitotic dna damage checkpointGO:004477340.015
positive regulation of protein complex assemblyGO:003133420.015
response to uvGO:000941130.015
regulation of vitamin metabolic processGO:003065660.015
neuron recognitionGO:0008038180.015
locomotionGO:00400113130.015
lateral mesoderm developmentGO:0048368230.015
homeostasis of number of cells within a tissueGO:004887340.015
hematopoietic progenitor cell differentiationGO:0002244230.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
ectodermal cell fate specificationGO:000171520.015
muscle cell developmentGO:00550011150.015
regulation of cytokine productionGO:000181730.015
negative regulation of catalytic activityGO:0043086210.015
regulation of cellular protein metabolic processGO:0032268520.015
centrosome organizationGO:005129710.015
brain developmentGO:00074202930.015
response to axon injuryGO:0048678140.015
negative regulation of cell deathGO:0060548600.015
cellular carbohydrate metabolic processGO:004426240.015
cellular response to stressGO:0033554620.015
cell divisionGO:0051301200.015
intermediate mesoderm developmentGO:004838920.015
skeletal muscle tissue developmentGO:0007519670.015
regulation of chromosome segregationGO:005198310.015
nuclear exportGO:005116810.015
cell maturationGO:0048469230.015
nucleocytoplasmic transportGO:000691340.015
regulation of reactive oxygen species metabolic processGO:200037720.015
regulation of microtubule cytoskeleton organizationGO:007050730.014
transcription from rna polymerase ii promoterGO:0006366800.014
carboxylic acid metabolic processGO:0019752220.014
central nervous system neuron differentiationGO:0021953740.014
regulation of primary metabolic processGO:00800903110.014
chemotaxisGO:00069351040.014
cellular amino acid metabolic processGO:000652070.014
regulation of alternative mrna splicing via spliceosomeGO:000038110.014
regulation of cellular protein catabolic processGO:190336210.014
negative regulation of protein phosphorylationGO:000193340.014
regulation of bone remodelingGO:004685020.014
Mouse
positive regulation of striated muscle tissue developmentGO:004584410.014
cardiac atrium morphogenesisGO:000320920.014
hematopoietic stem cell migrationGO:003570140.014
g2 dna damage checkpointGO:003157230.014
cell cycle arrestGO:000705010.014
regulation of mrna processingGO:005068430.014
regulation of microtubule polymerization or depolymerizationGO:003111030.014
spliceosomal snrnp assemblyGO:000038720.014
negative regulation of myeloid leukocyte differentiationGO:000276210.014
cell migration to the midline involved in heart developmentGO:0003318120.014
negative regulation of kinase activityGO:003367340.014
somatic muscle developmentGO:000752540.014
nucleobase containing compound metabolic processGO:00061392740.014
establishment of blood brain barrierGO:006085620.014
negative regulation of cellular biosynthetic processGO:0031327550.013

tfr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.645
hematopoietic system diseaseDOID:7400.403
immune system diseaseDOID:291400.403
endocrine gland cancerDOID:17000.192
thyroid cancerDOID:178100.192
cancerDOID:16200.192
organ system cancerDOID:005068600.192
disease of cellular proliferationDOID:1456600.192
disease of metabolismDOID:001466700.118
inherited metabolic disorderDOID:65500.118
thyroid carcinomaDOID:396300.112
bone marrow diseaseDOID:496100.042
nervous system diseaseDOID:86300.037
anemiaDOID:235500.024
colon carcinomaDOID:152000.017
colon cancerDOID:21900.017
large intestine cancerDOID:567200.017
gastrointestinal system cancerDOID:311900.017
colorectal cancerDOID:925600.017
intestinal cancerDOID:1015500.017
aplastic anemiaDOID:1244900.017
congenital hypoplastic anemiaDOID:134200.017
eye diseaseDOID:561400.015
retinal diseaseDOID:567900.015
retinal degenerationDOID:846600.015
eye and adnexa diseaseDOID:149200.015
sensory system diseaseDOID:005015500.015