Danio rerio

0 known processes

m17

IL-6 subfamily cytokine M17

(Aliases: si:dkeyp-15f12.5,lif)

m17 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signal transductionGO:00071654550.361
brain developmentGO:00074202930.303
regulation of signal transductionGO:00099662250.301
cell morphogenesis involved in differentiationGO:00009041950.232
morphogenesis of an epitheliumGO:00020093330.227
embryonic organ developmentGO:00485683810.216
neuron differentiationGO:00301823530.197
regulation of neuron differentiationGO:0045664560.194
ion transmembrane transportGO:0034220910.165
chordate embryonic developmentGO:00430092710.151
response to woundingGO:00096111160.146
immune system developmentGO:00025201910.145
response to stressGO:00069502630.143
cranial nerve developmentGO:0021545420.141
glial cell migrationGO:000834730.139
response to external stimulusGO:00096052640.137
diterpenoid metabolic processGO:0016101150.133
neurological system processGO:0050877620.132
regulation of multicellular organismal processGO:00512392770.132
organonitrogen compound biosynthetic processGO:1901566470.125
locomotionGO:00400113130.120
response to vitaminGO:003327330.119
chemosensory behaviorGO:000763510.115
positive regulation of biological processGO:00485182530.115
positive regulation of multicellular organismal processGO:0051240520.114
deathGO:00162651210.106
regulation of nervous system developmentGO:0051960900.103
cell part morphogenesisGO:00329902460.102
neuron projection regenerationGO:0031102160.102
regulation of cell communicationGO:00106462320.101
response to nutrientGO:000758430.100
agingGO:000756820.096
regulation of neurogenesisGO:0050767870.095
metal ion transportGO:0030001580.093
protein secretionGO:000930610.089
regulation of cell developmentGO:00602841000.088
axon developmentGO:00615641660.086
regulation of cell deathGO:00109411030.085
amine metabolic processGO:000930820.085
epithelial tube morphogenesisGO:00605621480.084
regulation of developmental processGO:00507932470.083
embryonic organ morphogenesisGO:00485622740.082
monocyte differentiationGO:003022420.080
regulation of signalingGO:00230512350.079
positive regulation of transportGO:005105020.076
generation of neuronsGO:00486993850.076
multicellular organismal response to stressGO:003355520.075
response to organic cyclic compoundGO:0014070510.075
sensory perception of painGO:001923310.074
regulation of multicellular organismal developmentGO:20000262230.074
positive regulation of nervous system developmentGO:0051962250.074
neuron developmentGO:00486662620.074
single organism biosynthetic processGO:0044711710.073
regulation of protein transportGO:005122330.073
positive regulation of muscle tissue developmentGO:190186310.072
small molecule metabolic processGO:0044281770.071
lateral line system developmentGO:0048925760.071
biosynthetic processGO:00090582940.070
regulation of response to stimulusGO:00485832690.069
gtp metabolic processGO:004603940.069
regulation of calcium ion transportGO:005192420.069
cellular component morphogenesisGO:00329893360.069
heart loopingGO:0001947940.067
cell surface receptor signaling pathwayGO:00071663250.066
regulation of apoptotic processGO:0042981980.066
neuron projection developmentGO:00311751800.065
ion transportGO:00068111140.065
positive regulation of neuron projection developmentGO:001097690.065
cation transportGO:0006812810.063
oxoacid metabolic processGO:0043436310.063
cell projection morphogenesisGO:00488582440.062
regulation of epithelial cell proliferationGO:005067830.059
response to drugGO:004249330.058
carbohydrate metabolic processGO:0005975120.057
positive regulation of signalingGO:0023056560.057
positive regulation of programmed cell deathGO:0043068290.056
digestive tract morphogenesisGO:00485462310.053
cell substrate adhesionGO:003158940.053
regulation of muscle contractionGO:000693730.053
homeostatic processGO:00425921420.052
regulation of metabolic processGO:00192223590.052
neuron projection morphogenesisGO:00488121610.052
regulation of extrinsic apoptotic signaling pathwayGO:200123630.052
muscle contractionGO:0006936180.051
single organism localizationGO:19025782250.050
organic acid metabolic processGO:0006082310.050
response to chemicalGO:00422213200.049
regulation of transmembrane transporter activityGO:002289820.049
regulation of ion transmembrane transporter activityGO:003241220.049
cell morphogenesisGO:00009022890.048
muscle organ developmentGO:00075171010.048
skeletal system developmentGO:00015011810.047
positive regulation of striated muscle tissue developmentGO:004584410.047
cognitionGO:005089010.047
cell deathGO:00082191210.047
cellular amine metabolic processGO:004410620.046
regulation of macromolecule metabolic processGO:00602553170.046
positive regulation of neurogenesisGO:0050769240.046
regulation of synaptic plasticityGO:004816710.046
regulation of purine nucleotide catabolic processGO:003312120.045
positive regulation of secretion by cellGO:190353210.045
muscle cell developmentGO:00550011150.045
organic substance biosynthetic processGO:19015762890.044
positive regulation of cellular processGO:00485222010.044
head developmentGO:00603223030.044
response to abiotic stimulusGO:00096281220.043
sensory perception of chemical stimulusGO:000760630.043
cellular biosynthetic processGO:00442492860.043
positive regulation of cell activationGO:005086710.043
mesenchymal cell developmentGO:0014031780.043
single organism metabolic processGO:00447102170.043
cellular carbohydrate metabolic processGO:004426240.042
regulation of gtpase activityGO:004308720.042
multicellular organism growthGO:003526440.042
regulation of organ growthGO:004662030.042
establishment of localizationGO:00512342440.042
cellular component movementGO:00069283350.041
hematopoietic or lymphoid organ developmentGO:00485341910.041
regulation of metal ion transportGO:001095940.040
regulation of cellular amino acid metabolic processGO:000652100.040
immune system processGO:00023762410.040
positive regulation of cell developmentGO:0010720250.040
positive regulation of catabolic processGO:000989640.040
stem cell proliferationGO:007208940.040
positive regulation of cell proliferationGO:0008284150.040
determination of bilateral symmetryGO:00098552040.040
neural crest cell developmentGO:0014032620.039
developmental growth involved in morphogenesisGO:0060560860.039
regulation of cell differentiationGO:00455951420.039
regulation of cell substrate adhesionGO:001081010.039
regulation of nucleoside metabolic processGO:000911820.039
cellular response to external stimulusGO:007149620.038
tube morphogenesisGO:00352393490.038
positive regulation of cellular catabolic processGO:003133130.038
peptide metabolic processGO:000651810.037
positive regulation of secretionGO:005104710.037
terpenoid metabolic processGO:0006721150.037
positive regulation of cell differentiationGO:0045597300.037
embryonic heart tube morphogenesisGO:00031431080.036
multicellular organismal signalingGO:0035637220.036
regulation of neuron projection developmentGO:0010975400.036
response to axon injuryGO:0048678140.036
neural crest cell differentiationGO:0014033720.036
regulation of multicellular organism growthGO:004001440.036
lateral line developmentGO:0048882660.036
extrinsic apoptotic signaling pathwayGO:009719130.035
regulation of bindingGO:005109830.035
positive regulation of muscle organ developmentGO:004863610.035
nerve developmentGO:0021675450.035
positive regulation of nucleotide catabolic processGO:003081310.035
regulation of cell projection organizationGO:0031344440.035
smooth muscle contractionGO:000693920.035
heart developmentGO:00075073130.035
regulation of cellular amine metabolic processGO:003323800.035
retinoid metabolic processGO:0001523150.035
actin filament based movementGO:003004810.035
positive regulation of response to external stimulusGO:003210390.034
multi organism processGO:00517041340.034
response to corticosteroidGO:003196010.034
mesenchyme developmentGO:00604851270.034
guanosine containing compound catabolic processGO:190106920.034
response to vitamin b3GO:003355220.034
cellular response to stressGO:0033554620.033
guanosine containing compound metabolic processGO:190106840.033
ribonucleotide biosynthetic processGO:0009260200.033
somite developmentGO:0061053960.033
mesenchymal cell differentiationGO:0048762870.033
positive regulation of apoptotic processGO:0043065290.033
system processGO:00030081850.032
phototransductionGO:000760220.032
cellular hormone metabolic processGO:0034754190.032
cellular response to organic substanceGO:00713101050.032
cell projection organizationGO:00300302840.032
regulation of programmed cell deathGO:00430671010.032
energy reserve metabolic processGO:000611220.031
protein metabolic processGO:00195381830.031
response to metal ionGO:0010038340.031
regulation of blood pressureGO:000821710.031
organelle organizationGO:00069962270.031
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.031
striated muscle cell developmentGO:00550021080.030
positive regulation of cell communicationGO:0010647560.030
response to glucocorticoidGO:005138410.030
regulation of heart growthGO:006042020.030
central nervous system myelinationGO:002201020.030
nuclear transportGO:005116940.030
striated muscle tissue developmentGO:00147061100.030
response to coldGO:000940940.029
macrophage differentiationGO:003022570.029
response to fatty acidGO:007054250.029
muscle cell differentiationGO:00426921390.029
cyclic nucleotide biosynthetic processGO:0009190180.029
endocrine processGO:005088620.029
phosphate containing compound metabolic processGO:00067961080.029
positive regulation of cell growthGO:003030750.029
organic cyclic compound metabolic processGO:19013603010.029
heterocycle metabolic processGO:00464832900.029
regulation of protein bindingGO:004339330.029
somitogenesisGO:0001756870.028
neuroblast proliferationGO:000740520.028
transmembrane transportGO:00550851200.028
localization of cellGO:00516742440.028
enteric nervous system developmentGO:0048484120.028
response to carbohydrateGO:000974330.028
embryonic hemopoiesisGO:0035162530.028
cellular macromolecule metabolic processGO:00442603910.028
inorganic cation transmembrane transportGO:0098662500.028
response to inorganic substanceGO:0010035380.028
regulation of nitrogen compound metabolic processGO:00511712510.028
nuclear importGO:005117030.027
determination of left right symmetryGO:00073681790.027
regulation of cell proliferationGO:0042127370.027
vitamin a metabolic processGO:000677610.027
carboxylic acid metabolic processGO:0019752220.027
stem cell developmentGO:0048864820.027
cellular protein metabolic processGO:00442671290.027
cell matrix adhesionGO:000716040.027
isoprenoid biosynthetic processGO:000829970.027
digestive system developmentGO:00551232890.027
nucleocytoplasmic transportGO:000691340.027
positive regulation of signal transductionGO:0009967560.027
regulation of cytoplasmic transportGO:190364940.027
small molecule biosynthetic processGO:0044283160.026
negative regulation of programmed cell deathGO:0043069580.026
positive regulation of stem cell proliferationGO:200064810.026
response to hydrogen peroxideGO:004254230.026
positive regulation of gtp catabolic processGO:003312610.026
cellular amino acid metabolic processGO:000652070.026
lipid storageGO:001991510.026
protein localization to nucleusGO:003450430.025
wound healingGO:0042060900.025
sensory system developmentGO:0048880760.025
regulation of tube sizeGO:003515020.025
regulation of establishment of protein localizationGO:007020140.025
regenerationGO:0031099910.025
ameboidal type cell migrationGO:00016671430.025
phagocytosisGO:000690930.025
larval developmentGO:000216420.025
embryonic skeletal system developmentGO:0048706970.025
adherens junction organizationGO:003433240.025
stem cell maintenanceGO:001982740.024
hindbrain developmentGO:0030902910.024
regulation of gtp catabolic processGO:003312420.024
digestive tract developmentGO:00485652650.024
regulation of transporter activityGO:003240920.024
regulation of cardiac muscle tissue developmentGO:005502410.024
gtp catabolic processGO:000618420.024
g1 s transition of mitotic cell cycleGO:000008210.024
positive regulation of cell adhesionGO:004578510.024
regulation of systemic arterial blood pressureGO:000307310.024
lipid homeostasisGO:005508830.024
positive regulation of cellular amine metabolic processGO:003324000.024
nitrogen compound metabolic processGO:00068073190.024
isoprenoid metabolic processGO:0006720150.023
small gtpase mediated signal transductionGO:000726480.023
cranial ganglion developmentGO:006155030.023
regulation of cellular component organizationGO:0051128860.023
response to monosaccharideGO:003428430.023
aromatic compound biosynthetic processGO:00194382170.023
forebrain cell migrationGO:002188510.023
response to acid chemicalGO:0001101170.023
autophagyGO:000691440.023
regulation of reproductive processGO:200024140.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
regulation of cell activationGO:005086510.022
regulation of nucleotide catabolic processGO:003081120.022
heart morphogenesisGO:00030071560.022
positive regulation of response to stimulusGO:0048584800.022
cellular response to extracellular stimulusGO:003166820.022
negative regulation of protein phosphorylationGO:000193340.022
growthGO:00400071740.022
cation transmembrane transportGO:0098655650.022
response to uvGO:000941130.022
macromolecule localizationGO:0033036540.022
cellular component disassemblyGO:002241110.022
cell proliferationGO:0008283800.022
stem cell differentiationGO:00488631170.022
establishment of protein localization to organelleGO:007259440.022
regulation of cell morphogenesis involved in differentiationGO:0010769380.022
negative regulation of biological processGO:00485193040.021
positive regulation of developmental processGO:0051094500.021
b cell activationGO:004211320.021
cellular aromatic compound metabolic processGO:00067252950.021
protein importGO:001703830.021
blood vessel developmentGO:00015682460.021
maintenance of locationGO:005123540.021
positive regulation of purine nucleotide catabolic processGO:003312310.021
regulation of cardiac muscle cell contractionGO:008600410.021
cellular ketone metabolic processGO:0042180110.021
regulation of striated muscle contractionGO:000694220.021
rho protein signal transductionGO:000726650.021
response to mechanical stimulusGO:0009612240.021
neuronal action potentialGO:0019228180.021
single organism nuclear importGO:190259330.020
alcohol biosynthetic processGO:004616520.020
regulation of axon regenerationGO:004867970.020
thermosensory behaviorGO:004004010.020
positive regulation of inflammatory responseGO:005072910.020
positive regulation of neuron differentiationGO:0045666120.020
regulation of biological qualityGO:00650082630.020
muscle structure developmentGO:00610611960.020
negative regulation of muscle contractionGO:004593210.020
mechanosensory lateral line system developmentGO:0048881490.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
centrosome organizationGO:005129710.020
cellular protein modification processGO:00064641000.020
regulation of autophagyGO:001050630.019
regulation of ion transmembrane transportGO:0034765180.019
positive regulation of muscle cell differentiationGO:005114910.019
cell growthGO:0016049570.019
protein targeting to nucleusGO:004474430.019
fat soluble vitamin metabolic processGO:000677540.019
organonitrogen compound metabolic processGO:1901564740.019
positive regulation of gtpase activityGO:004354710.019
fatty acid transportGO:001590810.019
cellular component assembly involved in morphogenesisGO:00109271070.019
negative regulation of apoptotic processGO:0043066550.019
negative regulation of protein kinase activityGO:000646940.019
macromolecule modificationGO:00434121110.018
heterocycle biosynthetic processGO:00181302150.018
phosphorus metabolic processGO:00067931090.018
cell cycle g1 s phase transitionGO:004484310.018
regulation of muscle hypertrophyGO:001474320.018
positive regulation of immune system processGO:0002684170.018
regionalizationGO:00030022740.018
divalent inorganic cation transportGO:0072511210.018
hemopoiesisGO:00300971830.018
protein import into nucleusGO:000660630.018
regulation of primary metabolic processGO:00800903110.018
neural crest cell migrationGO:0001755420.018
regulation of protein catabolic processGO:004217610.018
alcohol metabolic processGO:0006066110.018
regulation of ras gtpase activityGO:003231820.018
myeloid cell differentiationGO:0030099860.018
spermatid developmentGO:000728620.018
positive regulation of small gtpase mediated signal transductionGO:005105710.018
organ growthGO:0035265120.018
regulation of nucleobase containing compound metabolic processGO:00192192500.018
chemical homeostasisGO:0048878490.018
regulation of multicellular organismal metabolic processGO:004424620.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
regulation of transmembrane transportGO:0034762180.017
sensory organ developmentGO:00074233930.017
posterior lateral line developmentGO:0048916380.017
leukocyte proliferationGO:007066110.017
regulation of reactive oxygen species metabolic processGO:200037720.017
actin mediated cell contractionGO:007025210.017
nucleobase containing compound biosynthetic processGO:00346542050.017
regulation of biosynthetic processGO:00098892500.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
programmed cell deathGO:00125011190.017
regulation of muscle organ developmentGO:004863490.017
protein dephosphorylationGO:000647030.017
membrane hyperpolarizationGO:006008110.017
cellular protein catabolic processGO:004425740.017
regulation of dendrite morphogenesisGO:004881430.017
camera type eye developmentGO:00430102220.017
neuron projection guidanceGO:0097485860.016
posterior lateral line system developmentGO:0048915460.016
positive regulation of ras gtpase activityGO:003232010.016
regulation of developmental growthGO:0048638380.016
vasculature developmentGO:00019442780.016
myeloid leukocyte differentiationGO:0002573150.016
embryonic heart tube developmentGO:00350501330.016
positive regulation of cell cycleGO:004578730.016
fin developmentGO:0033333770.016
alpha amino acid metabolic processGO:190160530.016
developmental cell growthGO:0048588520.016
regulation of phosphate metabolic processGO:0019220430.016
negative regulation of kinase activityGO:003367340.016
cell migrationGO:00164772370.016
muscle system processGO:0003012200.016
cellular response to nutrient levelsGO:003166920.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
positive regulation of map kinase activityGO:004340630.016
apoptotic processGO:00069151160.016
compound eye developmentGO:004874920.016
negative regulation of catabolic processGO:000989530.016
regulation of cytokine productionGO:000181730.015
regulation of cell shapeGO:000836010.015
regulation of neural precursor cell proliferationGO:200017730.015
cardiocyte differentiationGO:0035051440.015
embryonic skeletal joint morphogenesisGO:006027230.015
cellular aldehyde metabolic processGO:000608140.015
skeletal muscle organ developmentGO:0060538780.015
positive regulation of epithelial cell migrationGO:001063420.015
regulation of cardiac muscle contractionGO:005511720.015
phagocytosis engulfmentGO:000691110.015
peptide transportGO:001583310.015
peptidyl serine phosphorylationGO:001810510.015
detection of chemical stimulusGO:000959340.015
sodium ion transportGO:0006814240.015
transmission of nerve impulseGO:0019226190.015
regulation of molecular functionGO:0065009700.015
membrane invaginationGO:001032410.015
regulation of neuron projection regenerationGO:007057070.014
muscle cell migrationGO:001481240.014
cellular response to radiationGO:007147840.014
negative regulation of multicellular organismal processGO:0051241690.014
oxidation reduction processGO:0055114410.014
inorganic ion transmembrane transportGO:0098660570.014
action potentialGO:0001508190.014
regulation of inflammatory responseGO:005072720.014
cytoskeleton organizationGO:0007010960.014
determination of heart left right asymmetryGO:00613711170.014
autonomic nervous system developmentGO:0048483190.014
glycerolipid biosynthetic processGO:004501710.014
striated muscle contractionGO:0006941120.014
regulation of rho protein signal transductionGO:003502320.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
single organism cellular localizationGO:1902580460.014
protein stabilizationGO:005082120.014
regulation of neuron migrationGO:200122220.014
nephron morphogenesisGO:007202820.014
skeletal system morphogenesisGO:00487051020.014
muscle hypertrophyGO:001489620.014
nucleobase containing compound metabolic processGO:00061392740.014
regulation of response to woundingGO:1903034110.014
nitric oxide metabolic processGO:004620920.014
regulation of blood vessel sizeGO:005088020.014
cellular lipid metabolic processGO:0044255360.014
fertilizationGO:000956630.014
cellular amide metabolic processGO:004360340.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
positive regulation of cytokine productionGO:000181920.014
regulation of cell growthGO:0001558290.013
myelinationGO:0042552180.013
regulation of dendrite developmentGO:005077330.013
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.013
developmental growthGO:00485891660.013
endosomal transportGO:001619720.013
regulation of receptor activityGO:001046920.013
response to hexoseGO:000974630.013
apoptotic signaling pathwayGO:0097190230.013
positive regulation of neural precursor cell proliferationGO:200017910.013
diterpenoid biosynthetic processGO:001610270.013
sensory perceptionGO:0007600390.013
axonogenesisGO:00074091520.013
sympathetic nervous system developmentGO:004848530.013
cell adhesion mediated by integrinGO:003362710.013
organic substance transportGO:0071702580.013
positive regulation of multi organism processGO:004390230.013
single organism organelle organizationGO:19025891990.013
circulatory system processGO:0003013870.013
ras protein signal transductionGO:000726570.013
proepicardium developmentGO:000334240.013
lipid biosynthetic processGO:0008610220.013
cardiac conductionGO:006133730.013
protein modification processGO:00362111000.013
ear developmentGO:00435831270.013
taxisGO:00423301090.013
spermatid differentiationGO:004851520.013
regulation of response to stressGO:0080134360.013
positive regulation of cellular biosynthetic processGO:0031328680.013
embryonic skeletal joint developmentGO:007249830.013
transcription dna templatedGO:00063511810.013
regulation of cellular ketone metabolic processGO:001056570.013
detection of temperature stimulusGO:001604800.013
positive regulation of striated muscle cell differentiationGO:005115510.013
negative regulation of epithelial cell proliferationGO:005068010.013
cilium organizationGO:0044782710.013
regulation of skeletal muscle tissue developmentGO:004864140.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
organ regenerationGO:003110010.013
g protein coupled receptor signaling pathwayGO:0007186740.012
cell cell signalingGO:0007267520.012
blood vessel morphogenesisGO:00485142160.012
embryo development ending in birth or egg hatchingGO:00097922710.012
regulation of transcription dna templatedGO:00063552130.012
hatchingGO:003518840.012
intracellular signal transductionGO:0035556850.012
regulation of protein import into nucleusGO:004230620.012
angiogenesisGO:00015251580.012
positive regulation of neuron projection regenerationGO:007057230.012
regulation of endocrine processGO:004406020.012
somatic muscle developmentGO:000752540.012
organic cyclic compound biosynthetic processGO:19013622230.012
negative regulation of developmental processGO:0051093650.012
regulation of actin filament based movementGO:190311510.012
midbrain developmentGO:0030901280.012
reactive oxygen species metabolic processGO:007259360.012
positive regulation of wound healingGO:009030310.012

m17 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.041
cancerDOID:16200.041
organ system cancerDOID:005068600.036
disease of metabolismDOID:001466700.031
disease of anatomical entityDOID:700.025
musculoskeletal system diseaseDOID:1700.025
bone diseaseDOID:008000100.025
connective tissue diseaseDOID:6500.025
acquired metabolic diseaseDOID:006015800.017
amyloidosisDOID:912000.017
nervous system diseaseDOID:86300.016
brain diseaseDOID:93600.014
central nervous system diseaseDOID:33100.014
epilepsy syndromeDOID:182600.014
idiopathic generalized epilepsyDOID:182700.014