Danio rerio

0 known processes

irge4

immunity-related GTPase family, e4

(Aliases: zgc:158767)

irge4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.087
larval developmentGO:000216420.084
signal transductionGO:00071654550.075
cellular protein catabolic processGO:004425740.060
multicellular organism growthGO:003526440.052
maintenance of locationGO:005123540.052
positive regulation of transportGO:005105020.050
proteasomal protein catabolic processGO:001049820.047
amine metabolic processGO:000930820.046
embryonic organ developmentGO:00485683810.045
embryonic organ morphogenesisGO:00485622740.045
cell surface receptor signaling pathwayGO:00071663250.045
negative regulation of biological processGO:00485193040.045
modification dependent macromolecule catabolic processGO:004363230.043
tube morphogenesisGO:00352393490.043
proteolysis involved in cellular protein catabolic processGO:005160330.043
negative regulation of protein phosphorylationGO:000193340.042
protein localization to nucleusGO:003450430.042
positive regulation of cell cycleGO:004578730.042
regulation of multicellular organism growthGO:004001440.042
phagocytosisGO:000690930.042
brain developmentGO:00074202930.042
regulation of synaptic plasticityGO:004816710.041
sensory organ developmentGO:00074233930.041
nuclear transportGO:005116940.041
regulation of multicellular organismal processGO:00512392770.041
head developmentGO:00603223030.040
digestive tract developmentGO:00485652650.040
ubiquitin dependent protein catabolic processGO:000651130.040
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.039
nitrogen compound metabolic processGO:00068073190.039
Mouse
cellular aromatic compound metabolic processGO:00067252950.039
Mouse
autophagyGO:000691440.038
Mouse
regionalizationGO:00030022740.038
sleepGO:003043110.038
stem cell maintenanceGO:001982740.038
nucleocytoplasmic transportGO:000691340.037
cellular amine metabolic processGO:004410620.037
digestive system developmentGO:00551232890.037
regulation of macromolecule metabolic processGO:00602553170.037
central nervous system developmentGO:00074173870.036
nucleic acid metabolic processGO:00903042440.036
regulation of response to stimulusGO:00485832690.036
modification dependent protein catabolic processGO:001994130.036
regulation of cellular amine metabolic processGO:003323800.036
adult behaviorGO:003053420.036
organic substance biosynthetic processGO:19015762890.035
regulation of establishment of protein localizationGO:007020140.035
response to chemicalGO:00422213200.035
Mouse
anterior posterior pattern specificationGO:00099521520.035
single organism localizationGO:19025782250.035
heart developmentGO:00075073130.035
negative regulation of protein kinase activityGO:000646940.034
establishment of protein localization to organelleGO:007259440.034
negative regulation of kinase activityGO:003367340.034
positive regulation of catabolic processGO:000989640.034
cognitionGO:005089010.034
aromatic compound biosynthetic processGO:00194382170.033
gastrulationGO:00073692080.033
gene expressionGO:00104672520.033
heterocycle metabolic processGO:00464832900.033
Mouse
cellular response to external stimulusGO:007149620.033
cellular biosynthetic processGO:00442492860.033
vasculature developmentGO:00019442780.033
cellular ketone metabolic processGO:0042180110.033
stem cell proliferationGO:007208940.032
sensory perception of chemical stimulusGO:000760630.032
negative regulation of cellular processGO:00485232830.032
regulation of metabolic processGO:00192223590.032
Mouse
response to drugGO:004249330.031
hormone transportGO:000991420.031
regulation of protein transportGO:005122330.031
locomotionGO:00400113130.031
regulation of cellular amino acid metabolic processGO:000652100.030
cellular macromolecule metabolic processGO:00442603910.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
establishment of localizationGO:00512342440.030
digestive tract morphogenesisGO:00485462310.030
system processGO:00030081850.030
morphogenesis of an epitheliumGO:00020093330.030
heterocycle biosynthetic processGO:00181302150.030
cellular nitrogen compound metabolic processGO:00346412900.030
Mouse
positive regulation of cellular catabolic processGO:003133130.029
regulation of developmental processGO:00507932470.029
organic cyclic compound metabolic processGO:19013603010.029
Mouse
positive regulation of cellular component biogenesisGO:004408930.029
protein targeting to nucleusGO:004474430.029
regulation of gene expressionGO:00104682650.029
nuclear importGO:005117030.029
regulation of signalingGO:00230512350.029
regulation of autophagyGO:001050630.028
Mouse
oxoacid metabolic processGO:0043436310.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
regulation of reactive oxygen species metabolic processGO:200037720.027
cellular component movementGO:00069283350.027
regulation of signal transductionGO:00099662250.027
positive regulation of cytosolic calcium ion concentrationGO:000720440.027
neuron neuron synaptic transmissionGO:000727010.027
organic acid metabolic processGO:0006082310.027
female sex differentiationGO:004666040.027
localization of cellGO:00516742440.027
protein import into nucleusGO:000660630.027
regulation of nitrogen compound metabolic processGO:00511712510.027
immune system processGO:00023762410.027
regulation of circadian rhythmGO:004275240.026
regulation of biological qualityGO:00650082630.026
regulation of cell shapeGO:000836010.026
regulation of cell communicationGO:00106462320.026
hormone secretionGO:004687920.026
protein importGO:001703830.026
response to stressGO:00069502630.026
Mouse
chordate embryonic developmentGO:00430092710.026
phagocytosis engulfmentGO:000691110.026
meiotic nuclear divisionGO:000712640.026
regulation of cytoplasmic transportGO:190364940.026
regulation of cellular metabolic processGO:00313233200.026
Mouse
macromolecule biosynthetic processGO:00090592270.026
blood vessel developmentGO:00015682460.025
cytokinesisGO:000091030.025
carboxylic acid metabolic processGO:0019752220.025
organelle organizationGO:00069962270.025
single organism nuclear importGO:190259330.025
generation of neuronsGO:00486993850.025
regulation of cellular ketone metabolic processGO:001056570.025
regulation of synapse organizationGO:005080730.025
nucleobase containing compound metabolic processGO:00061392740.025
Mouse
regulation of cytokine productionGO:000181730.025
cellular response to extracellular stimulusGO:003166820.025
biosynthetic processGO:00090582940.025
muscle structure developmentGO:00610611960.025
tissue remodelingGO:004877140.025
striated muscle cell developmentGO:00550021080.025
regulation of protein catabolic processGO:004217610.024
cellular amino acid metabolic processGO:000652070.024
synaptic growth at neuromuscular junctionGO:005112420.024
regulation of primary metabolic processGO:00800903110.024
rna metabolic processGO:00160702190.024
small molecule metabolic processGO:0044281770.024
Mouse
camera type eye developmentGO:00430102220.024
regulation of neuronal synaptic plasticityGO:004816810.024
cell migrationGO:00164772370.024
regulation of meiotic cell cycleGO:005144510.024
single organism metabolic processGO:00447102170.024
Mouse
regulation of neural precursor cell proliferationGO:200017730.024
positive regulation of secretion by cellGO:190353210.024
meiotic cell cycle processGO:190304630.024
peptide transportGO:001583310.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
regulation of synapse assemblyGO:005196330.024
regulation of stem cell proliferationGO:007209120.024
eye developmentGO:00016542770.023
positive regulation of biological processGO:00485182530.023
response to corticosteroidGO:003196010.023
development of primary female sexual characteristicsGO:004654540.023
regulation of multicellular organismal developmentGO:20000262230.023
gtp catabolic processGO:000618420.023
Mouse
protein metabolic processGO:00195381830.023
single organism transportGO:00447652060.023
regulation of macromolecule biosynthetic processGO:00105562250.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
cellular response to nutrient levelsGO:003166920.023
protein localization to plasma membraneGO:007265910.023
positive regulation of apoptotic signaling pathwayGO:200123510.023
cell substrate adhesionGO:003158940.023
gtp metabolic processGO:004603940.023
Mouse
sensory organ morphogenesisGO:00905962000.023
guanosine containing compound metabolic processGO:190106840.023
Mouse
transportGO:00068102200.022
neurotransmitter secretionGO:000726920.022
female gonad developmentGO:000858540.022
positive regulation of secretionGO:005104710.022
nucleobase containing compound biosynthetic processGO:00346542050.022
organonitrogen compound metabolic processGO:1901564740.022
Mouse
regulation of blood pressureGO:000821710.022
response to organic substanceGO:00100331530.022
Mouse
regulation of biosynthetic processGO:00098892500.022
response to uvGO:000941130.021
embryo development ending in birth or egg hatchingGO:00097922710.021
lipid storageGO:001991510.021
guanosine containing compound catabolic processGO:190106920.021
Mouse
i kappab kinase nf kappab signalingGO:000724940.021
regulation of nucleocytoplasmic transportGO:004682220.021
determination of left right symmetryGO:00073681790.021
regulation of dendrite developmentGO:005077330.021
cellular carbohydrate metabolic processGO:004426240.021
regulation of hormone secretionGO:004688320.021
extrinsic apoptotic signaling pathwayGO:009719130.021
meiotic chromosome segregationGO:004513230.021
regulation of reproductive processGO:200024140.021
blood vessel morphogenesisGO:00485142160.021
cell morphogenesisGO:00009022890.021
mitochondrion organizationGO:000700540.021
cellular pigmentationGO:0033059300.021
response to external stimulusGO:00096052640.021
Mouse
response to carbohydrateGO:000974330.021
exocytosisGO:000688710.021
single organism organelle organizationGO:19025891990.021
growthGO:00400071740.021
production of molecular mediator of immune responseGO:000244020.020
striated muscle tissue developmentGO:00147061100.020
specification of symmetryGO:00097992040.020
chemosensory behaviorGO:000763510.020
regulation of protein localization to nucleusGO:190018020.020
regulation of bindingGO:005109830.020
transcription dna templatedGO:00063511810.020
regulation of wound healingGO:006104120.020
membrane invaginationGO:001032410.020
cell motilityGO:00488702440.020
regulation of cell activationGO:005086510.020
organic cyclic compound biosynthetic processGO:19013622230.020
multi organism processGO:00517041340.020
Mouse
regulation of metal ion transportGO:001095940.020
cellular component morphogenesisGO:00329893360.020
regulation of protein ubiquitinationGO:003139630.020
positive regulation of cellular processGO:00485222010.020
peptidyl lysine acetylationGO:001839420.019
locomotor rhythmGO:004547530.019
secondary metabolic processGO:001974830.019
regulation of protein targetingGO:190353320.019
regulation of protein import into nucleusGO:004230620.019
synaptic vesicle transportGO:004848910.019
internal protein amino acid acetylationGO:000647520.019
regulation of cellular biosynthetic processGO:00313262450.019
maternal determination of anterior posterior axis embryoGO:000835840.019
positive regulation of cytokine productionGO:000181920.019
nucleic acid templated transcriptionGO:00976591810.019
single organism membrane fusionGO:004480120.019
regulation of transcription dna templatedGO:00063552130.019
actin filament based movementGO:003004810.019
cellular response to chemical stimulusGO:00708871570.019
Mouse
regulation of protein complex assemblyGO:004325430.019
rna localizationGO:000640340.019
actin polymerization or depolymerizationGO:000815420.019
regulation of stem cell differentiationGO:200073640.018
negative regulation of map kinase activityGO:004340720.018
response to nutrientGO:000758430.018
regulation of intracellular protein transportGO:003315730.018
peptidyl serine phosphorylationGO:001810510.018
endocrine processGO:005088620.018
cell projection morphogenesisGO:00488582440.018
negative regulation of catabolic processGO:000989530.018
cellular component assembly involved in morphogenesisGO:00109271070.018
response to amino acidGO:004320020.018
protein acetylationGO:000647320.018
determination of bilateral symmetryGO:00098552040.018
angiogenesisGO:00015251580.018
spermatid differentiationGO:004851520.018
compound eye developmentGO:004874920.018
regulation of tube sizeGO:003515020.018
organelle fusionGO:004828430.018
response to alkaloidGO:004327920.018
wound healingGO:0042060900.018
cellular macromolecule biosynthetic processGO:00346452240.018
cellular response to oxygen levelsGO:007145310.018
regulation of blood vessel sizeGO:005088020.018
regulation of rna metabolic processGO:00512522240.018
negative regulation of protein serine threonine kinase activityGO:007190120.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
response to monosaccharideGO:003428430.017
single fertilizationGO:000733830.017
ribonucleoside monophosphate catabolic processGO:000915840.017
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.017
liver developmentGO:0001889960.017
forebrain developmentGO:0030900960.017
positive regulation of cellular amine metabolic processGO:003324000.017
transmembrane transportGO:00550851200.017
carbohydrate biosynthetic processGO:001605110.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
retina development in camera type eyeGO:00600411460.017
antimicrobial humoral responseGO:001973020.017
fertilizationGO:000956630.017
regulation of cellular protein catabolic processGO:190336210.017
intracellular signal transductionGO:0035556850.017
carbohydrate homeostasisGO:003350010.017
pigment granule localizationGO:0051875250.017
oocyte anterior posterior axis specificationGO:000731440.017
dorsal ventral pattern formationGO:00099531250.017
organelle assemblyGO:00709251100.017
regulation of anatomical structure morphogenesisGO:00226031300.017
nuclear exportGO:005116810.017
response to glucocorticoidGO:005138410.017
heart morphogenesisGO:00030071560.017
golgi vesicle transportGO:004819330.017
purine nucleoside monophosphate catabolic processGO:000912840.017
protein acylationGO:004354330.017
leukocyte proliferationGO:007066110.017
cellular protein metabolic processGO:00442671290.017
phosphate containing compound metabolic processGO:00067961080.017
Mouse
peptidyl serine modificationGO:001820920.017
skeletal system developmentGO:00015011810.017
adherens junction organizationGO:003433240.017
lipid catabolic processGO:001604240.017
positive regulation of cytoskeleton organizationGO:005149530.017
regulation of nucleic acid templated transcriptionGO:19035062130.016
internal peptidyl lysine acetylationGO:001839320.016
response to hexoseGO:000974630.016
sequestering of metal ionGO:005123830.016
glucose homeostasisGO:004259310.016
cellular component assemblyGO:00226071700.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
interspecies interaction between organismsGO:004441940.016
negative regulation of metabolic processGO:0009892860.016
cell part morphogenesisGO:00329902460.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
regulation of cell substrate adhesionGO:001081010.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
synaptic vesicle localizationGO:009747910.016
regulation of dna replicationGO:000627530.016
protein polymerizationGO:005125840.016
nucleoside monophosphate catabolic processGO:000912540.016
regulation of sequestering of calcium ionGO:005128240.016
cellular localizationGO:0051641970.016
protein secretionGO:000930610.016
membrane fusionGO:006102520.016
blood circulationGO:0008015870.016
b cell activationGO:004211320.016
ameboidal type cell migrationGO:00016671430.016
phosphatidylinositol mediated signalingGO:004801520.016
spermatid developmentGO:000728620.016
cytoplasm organizationGO:000702840.016
developmental growthGO:00485891660.016
cellular response to starvationGO:000926710.016
regulation of muscle contractionGO:000693730.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
rna biosynthetic processGO:00327741810.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
cellular response to hypoxiaGO:007145610.016
cilium morphogenesisGO:0060271850.016
developmental programmed cell deathGO:001062340.015
neuron differentiationGO:00301823530.015
negative regulation of macromolecule metabolic processGO:0010605760.015
cellular response to organic substanceGO:00713101050.015
Mouse
embryonic heart tube morphogenesisGO:00031431080.015
lymphocyte proliferationGO:004665110.015
endocrine hormone secretionGO:006098620.015
cell projection organizationGO:00300302840.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
atp catabolic processGO:000620040.015
regulation of nucleoside metabolic processGO:000911820.015
protein stabilizationGO:005082120.015
cilium assemblyGO:0042384580.015
regulation of erk1 and erk2 cascadeGO:007037240.015
phosphatidylinositol 3 kinase signalingGO:001406520.015
cellular response to xenobiotic stimulusGO:0071466350.015
negative regulation of cellular catabolic processGO:003133030.015
regulation of dendrite morphogenesisGO:004881430.015
cellular amide metabolic processGO:004360340.015
inner ear developmentGO:00488391260.015
g1 s transition of mitotic cell cycleGO:000008210.015
ear developmentGO:00435831270.015
cellular component biogenesisGO:00440851780.015
hepaticobiliary system developmentGO:0061008980.015
positive regulation of protein complex assemblyGO:003133420.015
gland developmentGO:00487321430.015
regulation of endocrine processGO:004406020.015
regulation of myotube differentiationGO:001083020.015
cytoskeleton dependent cytokinesisGO:006164030.015
positive regulation of map kinase activityGO:004340630.015
homeostatic processGO:00425921420.015
cation transportGO:0006812810.015
regulation of localizationGO:00328791040.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.014
cation transmembrane transportGO:0098655650.014
cell matrix adhesionGO:000716040.014
circadian sleep wake cycle sleepGO:005080210.014
inositol lipid mediated signalingGO:004801720.014
regulation of inflammatory responseGO:005072720.014
mesenchyme developmentGO:00604851270.014
tissue regenerationGO:0042246740.014
negative regulation of cytoplasmic transportGO:190365020.014
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.014
neurotransmitter transportGO:000683620.014
release of sequestered calcium ion into cytosolGO:005120930.014
muscle cell developmentGO:00550011150.014
cellular protein modification processGO:00064641000.014
somatic stem cell maintenanceGO:003501910.014
immune system developmentGO:00025201910.014
response to glucoseGO:000974930.014
positive regulation of dna metabolic processGO:005105410.014
muscle tissue developmentGO:00605371100.014
regulation of cell differentiationGO:00455951420.014
negative regulation of mapk cascadeGO:004340940.014
hemopoiesisGO:00300971830.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
somitogenesisGO:0001756870.014
sensory system developmentGO:0048880760.014
regulation of mrna processingGO:005068430.014
establishment of localization in cellGO:0051649770.014
translational initiationGO:000641330.014
xenobiotic metabolic processGO:000680540.014
regulation of rna biosynthetic processGO:20011412130.014
positive regulation of nucleotide catabolic processGO:003081310.014
segmentationGO:0035282970.014
regulation of calcium ion transportGO:005192420.014
response to woundingGO:00096111160.014
rna 3 end processingGO:003112320.014
determination of heart left right asymmetryGO:00613711170.014
ion transportGO:00068111140.014
actin filament polymerizationGO:003004120.014
multicellular organismal signalingGO:0035637220.014
mitochondrial transportGO:000683920.014
regulation of neurogenesisGO:0050767870.013
epithelial tube morphogenesisGO:00605621480.013
programmed cell deathGO:00125011190.013
negative regulation of signal transductionGO:0009968940.013
neuroblast proliferationGO:000740520.013
behaviorGO:0007610740.013
cellular component disassemblyGO:002241110.013
heart loopingGO:0001947940.013
negative regulation of synapse assemblyGO:005196420.013
neuron developmentGO:00486662620.013
olfactory lobe developmentGO:002198840.013
ventricular cardiac muscle tissue developmentGO:000322930.013
deathGO:00162651210.013
cytoskeleton organizationGO:0007010960.013
erk1 and erk2 cascadeGO:007037140.013
establishment of synaptic vesicle localizationGO:009748010.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
intracellular mrna localizationGO:000829810.013
regulation of nucleotide catabolic processGO:003081120.013
inorganic cation transmembrane transportGO:0098662500.013
stem cell divisionGO:001714510.013
positive regulation of cell activationGO:005086710.013
cytosolic calcium ion transportGO:006040130.013
dicarboxylic acid transportGO:000683510.013
amino acid transportGO:000686520.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
response to topologically incorrect proteinGO:003596620.013
cellular response to decreased oxygen levelsGO:003629410.013
cellular response to reactive oxygen speciesGO:003461420.013
somite developmentGO:0061053960.013
eye morphogenesisGO:00485921440.013
immunoglobulin mediated immune responseGO:001606430.013
cell cycle arrestGO:000705010.013
transcription from rna polymerase ii promoterGO:0006366800.013
microtubule organizing center organizationGO:003102310.013
superoxide metabolic processGO:000680120.013
ion transmembrane transportGO:0034220910.013
positive regulation of cell divisionGO:005178120.013
regulation of neurotransmitter secretionGO:004692810.013
negative regulation of response to stimulusGO:00485851040.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
regulation of purine nucleotide catabolic processGO:003312120.013
embryonic skeletal system developmentGO:0048706970.013
striated muscle cell differentiationGO:00511461290.013
small molecule catabolic processGO:004428230.013
regulation of production of molecular mediator of immune responseGO:000270010.012
response to xenobiotic stimulusGO:0009410450.012
g protein coupled receptor signaling pathwayGO:0007186740.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
positive regulation of nucleoside metabolic processGO:004597910.012
response to other organismGO:0051707970.012
Mouse
convergent extensionGO:00600261180.012
negative regulation of cell communicationGO:0010648960.012
apoptotic process involved in developmentGO:190274220.012
regulation of ion transmembrane transporter activityGO:003241220.012
reactive oxygen species biosynthetic processGO:190340910.012
negative regulation of multicellular organismal processGO:0051241690.012
calcium ion transport into cytosolGO:006040230.012
regulation of cell developmentGO:00602841000.012
appendage developmentGO:0048736800.012
neuromuscular process controlling balanceGO:005088530.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
muscle organ developmentGO:00075171010.012
cell cycle g1 s phase transitionGO:004484310.012
neurological system processGO:0050877620.012
negative regulation of cytokine productionGO:000181810.012
skeletal system morphogenesisGO:00487051020.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.012
establishment of vesicle localizationGO:0051650240.012
regulation of gtp catabolic processGO:003312420.012
regulation of programmed cell deathGO:00430671010.012
establishment of organelle localizationGO:0051656450.012
cortical actin cytoskeleton organizationGO:003086610.012
vacuolar transportGO:000703420.012
protein dephosphorylationGO:000647030.012
multicellular organismal macromolecule metabolic processGO:004425920.012
negative regulation of protein localization to nucleusGO:190018120.012
inorganic ion transmembrane transportGO:0098660570.012
positive regulation of stem cell proliferationGO:200064810.012
establishment of protein localization to plasma membraneGO:009000210.012

irge4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
cardiovascular system diseaseDOID:128700.031
musculoskeletal system diseaseDOID:1700.024
nervous system diseaseDOID:86300.016
disease of metabolismDOID:001466700.015
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
myopathyDOID:42300.012
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012
sensory system diseaseDOID:005015500.012