Danio rerio

39 known processes

dmbx1b

diencephalon/mesencephalon homeobox 1b

(Aliases: zgc:112395,mbx2)

dmbx1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron neuron synaptic transmissionGO:000727010.319
system processGO:00030081850.222
behaviorGO:0007610740.204
Mouse
larval developmentGO:000216420.175
neuron differentiationGO:00301823530.173
sensory system developmentGO:0048880760.170
head developmentGO:00603223030.161
cellular component movementGO:00069283350.139
morphogenesis of an epitheliumGO:00020093330.137
synaptic transmissionGO:0007268350.135
regulation of establishment of protein localizationGO:007020140.131
neuron developmentGO:00486662620.129
response to abiotic stimulusGO:00096281220.128
regulation of macromolecule metabolic processGO:00602553170.124
Zebrafish Mouse
cellular macromolecule metabolic processGO:00442603910.121
Zebrafish Mouse
central nervous system developmentGO:00074173870.120
cellular nitrogen compound biosynthetic processGO:00442712180.119
Zebrafish Mouse
regulation of gene expressionGO:00104682650.114
Zebrafish Mouse
lateral line developmentGO:0048882660.110
nucleocytoplasmic transportGO:000691340.097
nucleobase containing compound metabolic processGO:00061392740.095
Zebrafish Mouse
response to glucocorticoidGO:005138410.088
negative regulation of biological processGO:00485193040.084
Zebrafish Mouse
guanosine containing compound catabolic processGO:190106920.082
transportGO:00068102200.081
establishment of localizationGO:00512342440.080
response to chemicalGO:00422213200.079
generation of neuronsGO:00486993850.078
anterior posterior pattern specificationGO:00099521520.075
embryonic skeletal system morphogenesisGO:0048704930.073
adult behaviorGO:003053420.072
Mouse
rna metabolic processGO:00160702190.071
Zebrafish Mouse
response to woundingGO:00096111160.068
positive regulation of gtpase activityGO:004354710.067
regulation of synaptic plasticityGO:004816710.065
protein modification processGO:00362111000.063
gtp metabolic processGO:004603940.063
regulation of reproductive processGO:200024140.062
nuclear transportGO:005116940.061
heterocycle biosynthetic processGO:00181302150.061
Zebrafish Mouse
cell morphogenesis involved in differentiationGO:00009041950.061
mechanosensory lateral line system developmentGO:0048881490.059
single organism metabolic processGO:00447102170.058
response to corticosteroidGO:003196010.058
posterior lateral line system developmentGO:0048915460.058
skeletal system morphogenesisGO:00487051020.057
embryonic skeletal system developmentGO:0048706970.057
protein localization to nucleusGO:003450430.057
endothelial cell fate commitmentGO:006083930.056
positive regulation of purine nucleotide catabolic processGO:003312310.055
signal transductionGO:00071654550.054
camera type eye developmentGO:00430102220.054
gastrulationGO:00073692080.054
regulation of intracellular protein transportGO:003315730.053
metal ion transportGO:0030001580.053
guanosine containing compound metabolic processGO:190106840.052
positive regulation of cellular component biogenesisGO:004408930.051
cell migrationGO:00164772370.051
rna biosynthetic processGO:00327741810.050
Zebrafish Mouse
vasculature developmentGO:00019442780.050
regulation of metabolic processGO:00192223590.050
Zebrafish Mouse
embryonic cranial skeleton morphogenesisGO:0048701900.049
chordate embryonic developmentGO:00430092710.049
pole plasm assemblyGO:000731540.049
cellular protein metabolic processGO:00442671290.048
nuclear exportGO:005116810.048
regulation of transcription dna templatedGO:00063552130.048
Zebrafish Mouse
regulation of gtp catabolic processGO:003312420.048
epithelial cell differentiationGO:00308551160.048
regulation of calcium ion transportGO:005192420.047
response to stressGO:00069502630.046
positive regulation of metabolic processGO:00098931080.046
cellular component morphogenesisGO:00329893360.046
cell projection organizationGO:00300302840.045
cardiac cell fate commitmentGO:006091110.044
regulation of cellular metabolic processGO:00313233200.044
Zebrafish Mouse
negative regulation of multicellular organismal processGO:0051241690.044
single organism nuclear importGO:190259330.044
locomotionGO:00400113130.043
response to external stimulusGO:00096052640.043
negative regulation of biosynthetic processGO:0009890550.043
Zebrafish Mouse
regulation of cytoplasmic transportGO:190364940.043
response to light stimulusGO:0009416460.043
brain developmentGO:00074202930.042
heterocycle metabolic processGO:00464832900.042
Zebrafish Mouse
nucleic acid metabolic processGO:00903042440.042
Zebrafish Mouse
convergent extensionGO:00600261180.041
lymph vessel developmentGO:0001945270.040
neurological system processGO:0050877620.040
organic cyclic compound biosynthetic processGO:19013622230.040
Zebrafish Mouse
regionalizationGO:00030022740.040
gtp catabolic processGO:000618420.040
startle responseGO:000196440.039
positive regulation of biological processGO:00485182530.039
embryonic organ morphogenesisGO:00485622740.039
positive regulation of cellular biosynthetic processGO:0031328680.039
regulation of cellular biosynthetic processGO:00313262450.038
Zebrafish Mouse
positive regulation of nucleotide catabolic processGO:003081310.037
regulation of cell shapeGO:000836010.037
macromolecule modificationGO:00434121110.037
segmentationGO:0035282970.037
nuclear importGO:005117030.036
regulation of nucleoside metabolic processGO:000911820.036
positive regulation of nucleobase containing compound metabolic processGO:0045935690.036
cell cell signalingGO:0007267520.035
regulation of nucleobase containing compound metabolic processGO:00192192500.035
Zebrafish Mouse
response to radiationGO:0009314510.035
cognitionGO:005089010.035
mitochondrial transportGO:000683920.035
glial cell developmentGO:0021782200.034
regulation of nucleotide catabolic processGO:003081120.034
maintenance of locationGO:005123540.033
regulation of nucleocytoplasmic transportGO:004682220.033
establishment of protein localization to organelleGO:007259440.033
gene expressionGO:00104672520.033
Zebrafish Mouse
protein import into nucleusGO:000660630.033
regulation of primary metabolic processGO:00800903110.033
Zebrafish Mouse
mitochondrion organizationGO:000700540.033
g protein coupled receptor signaling pathwayGO:0007186740.033
hematopoietic or lymphoid organ developmentGO:00485341910.032
regenerationGO:0031099910.032
regulation of protein transportGO:005122330.032
cellular macromolecule biosynthetic processGO:00346452240.032
Zebrafish Mouse
somite developmentGO:0061053960.031
lymphatic endothelial cell differentiationGO:006083610.031
cellular aromatic compound metabolic processGO:00067252950.031
Zebrafish Mouse
liver developmentGO:0001889960.031
sensory perceptionGO:0007600390.030
lateral line system developmentGO:0048925760.030
protein targeting to nucleusGO:004474430.030
stem cell proliferationGO:007208940.029
negative regulation of nuclear divisionGO:005178430.029
response to endogenous stimulusGO:0009719830.029
epithelial tube morphogenesisGO:00605621480.029
organic acid metabolic processGO:0006082310.029
negative regulation of gene expressionGO:0010629650.029
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic processGO:20001122220.029
Zebrafish Mouse
regulation of cell substrate adhesionGO:001081010.028
cellular protein modification processGO:00064641000.028
embryonic organ developmentGO:00485683810.028
regulation of multicellular organismal processGO:00512392770.028
taxisGO:00423301090.028
negative regulation of macromolecule metabolic processGO:0010605760.027
Zebrafish Mouse
regulation of fatty acid metabolic processGO:001921710.027
cell morphogenesisGO:00009022890.027
phosphate containing compound metabolic processGO:00067961080.027
positive regulation of cellular processGO:00485222010.027
lipid storageGO:001991510.027
negative regulation of metabolic processGO:0009892860.026
Zebrafish Mouse
cellular response to external stimulusGO:007149620.026
cell projection morphogenesisGO:00488582440.026
positive regulation of transportGO:005105020.024
nucleobase containing compound biosynthetic processGO:00346542050.024
Zebrafish Mouse
dopaminergic neuron differentiationGO:0071542140.024
response to organic cyclic compoundGO:0014070510.024
cation transportGO:0006812810.024
phagocytosisGO:000690930.024
embryo development ending in birth or egg hatchingGO:00097922710.024
regulation of meiotic cell cycleGO:005144510.024
cell part morphogenesisGO:00329902460.024
transcription from rna polymerase iii promoterGO:000638310.023
regulation of purine nucleotide catabolic processGO:003312120.023
regulation of gtpase activityGO:004308720.023
negative regulation of cellular biosynthetic processGO:0031327550.023
Zebrafish Mouse
regulation of catalytic activityGO:0050790550.023
cell surface receptor signaling pathwayGO:00071663250.023
erk1 and erk2 cascadeGO:007037140.023
single organism behaviorGO:0044708240.022
Mouse
negative regulation of epithelial cell proliferationGO:005068010.022
cellular response to extracellular stimulusGO:003166820.022
cellular response to nutrient levelsGO:003166920.022
single organism intracellular transportGO:1902582250.022
b cell activationGO:004211320.022
positive regulation of cytosolic calcium ion concentrationGO:000720440.022
locomotory behaviorGO:0007626340.022
Mouse
protein phosphorylationGO:0006468470.021
neuron projection developmentGO:00311751800.021
regulation of dna replicationGO:000627530.021
regulation of transcription from rna polymerase iii promoterGO:000635910.021
neuroblast differentiationGO:001401610.021
agingGO:000756820.021
positive regulation of biosynthetic processGO:0009891680.021
positive regulation of gene expressionGO:0010628710.021
regulation of protein localization to nucleusGO:190018020.020
negative regulation of nitrogen compound metabolic processGO:0051172590.020
Zebrafish Mouse
cell motilityGO:00488702440.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
phosphorus metabolic processGO:00067931090.020
sensory perception of chemical stimulusGO:000760630.020
regulation of bindingGO:005109830.020
positive regulation of catabolic processGO:000989640.020
positive regulation of cellular metabolic processGO:0031325940.020
cellular nitrogen compound metabolic processGO:00346412900.020
Zebrafish Mouse
negative regulation of mitosisGO:004583930.020
synaptic growth at neuromuscular junctionGO:005112420.019
cellular ketone metabolic processGO:0042180110.019
regulation of protein import into nucleusGO:004230620.019
localization of cellGO:00516742440.019
regulation of cell matrix adhesionGO:000195210.019
heart developmentGO:00075073130.019
hemopoiesisGO:00300971830.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
Mouse
regulation of cell activationGO:005086510.019
regulation of molecular functionGO:0065009700.019
meiotic nuclear divisionGO:000712640.019
protein metabolic processGO:00195381830.019
immune system processGO:00023762410.019
glutamate receptor signaling pathwayGO:000721510.019
small molecule metabolic processGO:0044281770.019
regulation of biological qualityGO:00650082630.019
ion transportGO:00068111140.018
cellular response to endogenous stimulusGO:0071495680.018
macromolecule biosynthetic processGO:00090592270.018
Zebrafish Mouse
organic cyclic compound metabolic processGO:19013603010.018
Zebrafish Mouse
aromatic compound biosynthetic processGO:00194382170.018
Zebrafish Mouse
nitrogen compound metabolic processGO:00068073190.018
Zebrafish Mouse
cellular response to starvationGO:000926710.018
cytoplasm organizationGO:000702840.018
sensory perception of painGO:001923310.018
regulation of cytokine productionGO:000181730.018
neuromuscular process controlling balanceGO:005088530.018
muscle system processGO:0003012200.018
lymphangiogenesisGO:0001946250.018
circulatory system processGO:0003013870.017
regulation of multicellular organismal developmentGO:20000262230.017
cellular response to stressGO:0033554620.017
calcium ion transport into cytosolGO:006040230.017
cytosolic calcium ion transportGO:006040130.017
single organism localizationGO:19025782250.017
neuron projection morphogenesisGO:00488121610.017
wound healingGO:0042060900.017
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.017
neuron projection regenerationGO:0031102160.017
regulation of metal ion transportGO:001095940.017
regulation of nitrogen compound metabolic processGO:00511712510.016
Zebrafish Mouse
regulation of cellular amine metabolic processGO:003323800.016
negative regulation of nucleobase containing compound metabolic processGO:0045934590.016
Zebrafish Mouse
cellular response to chemical stimulusGO:00708871570.016
lymphocyte proliferationGO:004665110.016
negative regulation of protein kinase activityGO:000646940.016
retina layer formationGO:0010842240.016
multicellular organism growthGO:003526440.016
regulation of multicellular organism growthGO:004001440.016
peripheral nervous system neuron differentiationGO:0048934280.015
regulation of cellular ketone metabolic processGO:001056570.015
regulation of cellular amino acid metabolic processGO:000652100.015
cellular response to oxygen levelsGO:007145310.015
positive regulation of nucleoside metabolic processGO:004597910.015
negative regulation of intracellular protein transportGO:009031730.015
transmembrane transportGO:00550851200.015
positive regulation of cell adhesionGO:004578510.015
transmission of nerve impulseGO:0019226190.015
regulation of stem cell proliferationGO:007209120.015
regulation of nucleotide metabolic processGO:0006140170.015
regulation of ras gtpase activityGO:003231820.015
regulation of cell projection assemblyGO:006049140.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
positive regulation of rna metabolic processGO:0051254590.015
regulation of cell cycleGO:0051726520.014
fertilizationGO:000956630.014
regulation of protein targetingGO:190353320.014
regulation of rho protein signal transductionGO:003502320.014
somitogenesisGO:0001756870.014
collateral sprouting in absence of injuryGO:004866940.014
exocytosisGO:000688710.014
cell death in response to oxidative stressGO:003647320.014
positive regulation of ras gtpase activityGO:003232010.014
blood vessel morphogenesisGO:00485142160.014
chemosensory behaviorGO:000763510.014
nucleoside monophosphate catabolic processGO:000912540.014
epithelial cell fate commitmentGO:0072148110.014
response to steroid hormoneGO:0048545350.014
myeloid cell differentiationGO:0030099860.014
oocyte anterior posterior axis specificationGO:000731440.014
regulation of oligodendrocyte differentiationGO:004871310.014
establishment of synaptic vesicle localizationGO:009748010.014
angiogenesisGO:00015251580.014
negative regulation of reproductive processGO:200024230.013
cellular protein catabolic processGO:004425740.013
regulation of neuron differentiationGO:0045664560.013
cell substrate adhesionGO:003158940.013
heart morphogenesisGO:00030071560.013
regulation of cell differentiationGO:00455951420.013
protein importGO:001703830.013
skeletal system developmentGO:00015011810.013
transcription from rna polymerase ii promoterGO:0006366800.013
Mouse
lipid metabolic processGO:0006629520.013
positive regulation of multicellular organismal processGO:0051240520.013
regulation of macromolecule biosynthetic processGO:00105562250.013
Zebrafish Mouse
maternal determination of anterior posterior axis embryoGO:000835840.013
biosynthetic processGO:00090582940.013
Zebrafish Mouse
amine metabolic processGO:000930820.013
establishment of endothelial blood brain barrierGO:001404520.013
regulation of signalingGO:00230512350.013
cellular response to lipidGO:0071396390.013
regulation of epithelial cell proliferationGO:005067830.013
directional locomotionGO:003305810.013
nucleic acid templated transcriptionGO:00976591810.013
Zebrafish Mouse
lymphatic endothelial cell fate commitmentGO:006083810.013
ras protein signal transductionGO:000726570.012
lymph vessel morphogenesisGO:0036303250.012
forebrain developmentGO:0030900960.012
posttranscriptional regulation of gene expressionGO:0010608140.012
regulation of membrane potentialGO:0042391230.012
peripheral nervous system developmentGO:0007422550.012
detection of temperature stimulusGO:001604800.012
developmental growthGO:00485891660.012
Mouse
membrane invaginationGO:001032410.012
regulation of filopodium assemblyGO:005148920.012
axon cargo transportGO:000808820.012
receptor internalizationGO:003162320.012
protein localization to plasma membraneGO:007265910.012
positive regulation of cellular catabolic processGO:003133130.012
regulation of oocyte developmentGO:006028130.012
positive regulation of camp biosynthetic processGO:003081920.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
heart contractionGO:0060047710.012
positive regulation of cell substrate adhesionGO:001081110.012
regulation of rna biosynthetic processGO:20011412130.012
Zebrafish Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
blood vessel developmentGO:00015682460.012
cellular amine metabolic processGO:004410620.012
peptide transportGO:001583310.012
photoreceptor cell differentiationGO:0046530550.012
negative regulation of cellular catabolic processGO:003133030.012
negative regulation of cellular metabolic processGO:0031324770.011
Zebrafish Mouse
intracellular signal transductionGO:0035556850.011
cellular component assemblyGO:00226071700.011
regulation of tube sizeGO:003515020.011
action potentialGO:0001508190.011
positive regulation of gtp catabolic processGO:003312610.011
positive regulation of transcription dna templatedGO:0045893570.011
positive regulation of rna biosynthetic processGO:1902680570.011
antimicrobial humoral responseGO:001973020.011
posterior lateral line developmentGO:0048916380.011
regulation of glial cell differentiationGO:004568540.011
multicellular organismal reproductive processGO:0048609350.011
negative regulation of multi organism processGO:004390130.011
apical junction assemblyGO:004329710.011
detection of stimulusGO:0051606290.011
regulation of inflammatory responseGO:005072720.011
cellular lipid metabolic processGO:0044255360.011
epidermis developmentGO:0008544480.011
inositol lipid mediated signalingGO:004801720.011
locomotor rhythmGO:004547530.011
entrainment of circadian clock by photoperiodGO:004315310.011
myelinationGO:0042552180.011
rho protein signal transductionGO:000726650.011
adherens junction assemblyGO:003433310.011
regulation of cell maturationGO:190342910.011
mononuclear cell proliferationGO:003294310.011
regulation of synapse assemblyGO:005196330.011
carboxylic acid metabolic processGO:0019752220.011
developmental maturationGO:0021700340.011
multi organism processGO:00517041340.011
olfactory bulb developmentGO:002177240.011
response to drugGO:004249330.011
centrosome organizationGO:005129710.010
organic substance biosynthetic processGO:19015762890.010
Zebrafish Mouse
synapse organizationGO:0050808210.010
regulation of synapse organizationGO:005080730.010
proteolysis involved in cellular protein catabolic processGO:005160330.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
negative regulation of dna metabolic processGO:005105340.010
pharyngeal system developmentGO:0060037180.010
tube closureGO:006060610.010
response to ketoneGO:190165410.010
response to acid chemicalGO:0001101170.010
multicellular organismal signalingGO:0035637220.010

dmbx1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
cardiovascular system diseaseDOID:128700.016
nervous system diseaseDOID:86300.015
organ system cancerDOID:005068600.013