Danio rerio

0 known processes

kdsr

3-ketodihydrosphingosine reductase

(Aliases: MGC55947,fvt1,zgc:55947)

kdsr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.227
agingGO:000756820.158
establishment of localizationGO:00512342440.147
neuron developmentGO:00486662620.103
phagocytosisGO:000690930.096
cellular protein catabolic processGO:004425740.095
regulation of establishment of protein localizationGO:007020140.082
single organism metabolic processGO:00447102170.077
Human
single organism localizationGO:19025782250.077
regulation of developmental processGO:00507932470.074
digestive system developmentGO:00551232890.073
transportGO:00068102200.070
lipid storageGO:001991510.068
regulation of primary metabolic processGO:00800903110.067
peptidyl serine phosphorylationGO:001810510.065
maintenance of locationGO:005123540.065
establishment of protein localization to organelleGO:007259440.064
organelle organizationGO:00069962270.063
signal transductionGO:00071654550.061
proteolysis involved in cellular protein catabolic processGO:005160330.058
lipid catabolic processGO:001604240.057
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.057
negative regulation of signal transductionGO:0009968940.057
digestive tract developmentGO:00485652650.056
response to chemicalGO:00422213200.056
negative regulation of kinase activityGO:003367340.055
golgi vesicle transportGO:004819330.055
ubiquitin dependent protein catabolic processGO:000651130.055
regulation of cellular metabolic processGO:00313233200.054
regulation of metabolic processGO:00192223590.054
er to golgi vesicle mediated transportGO:000688810.053
single organism nuclear importGO:190259330.053
cytokinesisGO:000091030.052
cellular component morphogenesisGO:00329893360.052
cellular macromolecule metabolic processGO:00442603910.052
response to external stimulusGO:00096052640.052
generation of neuronsGO:00486993850.051
regulation of circadian rhythmGO:004275240.051
extrinsic apoptotic signaling pathwayGO:009719130.050
positive regulation of transportGO:005105020.050
regulation of multicellular organismal processGO:00512392770.050
positive regulation of cell cycleGO:004578730.049
regulation of protein transportGO:005122330.046
guanosine containing compound catabolic processGO:190106920.046
regulation of macromolecule metabolic processGO:00602553170.046
cellular amine metabolic processGO:004410620.046
proteasomal protein catabolic processGO:001049820.045
autophagyGO:000691440.045
modification dependent protein catabolic processGO:001994130.045
protein importGO:001703830.045
mitochondrion organizationGO:000700540.045
nuclear transportGO:005116940.045
single organism transportGO:00447652060.045
protein secretionGO:000930610.044
organic cyclic compound metabolic processGO:19013603010.043
growthGO:00400071740.043
protein metabolic processGO:00195381830.043
endosomal transportGO:001619720.043
protein import into nucleusGO:000660630.043
regulation of protein import into nucleusGO:004230620.043
cell projection morphogenesisGO:00488582440.043
single organism organelle organizationGO:19025891990.043
morphogenesis of an epitheliumGO:00020093330.042
tube morphogenesisGO:00352393490.042
chordate embryonic developmentGO:00430092710.042
negative regulation of protein phosphorylationGO:000193340.041
gtp catabolic processGO:000618420.041
cell part morphogenesisGO:00329902460.041
cell matrix adhesionGO:000716040.041
modification dependent macromolecule catabolic processGO:004363230.040
guanosine containing compound metabolic processGO:190106840.040
cellular component biogenesisGO:00440851780.039
regulation of response to stimulusGO:00485832690.039
enzyme linked receptor protein signaling pathwayGO:00071671060.039
localization within membraneGO:005166810.039
negative regulation of small gtpase mediated signal transductionGO:005105810.039
organic acid metabolic processGO:0006082310.038
cell surface receptor signaling pathwayGO:00071663250.038
stem cell maintenanceGO:001982740.038
protein localization to nucleusGO:003450430.038
positive regulation of biological processGO:00485182530.038
neuron differentiationGO:00301823530.038
gtp metabolic processGO:004603940.038
regulation of cytoplasmic transportGO:190364940.038
regulation of multicellular organism growthGO:004001440.037
apoptotic processGO:00069151160.037
regulation of protein complex assemblyGO:004325430.037
phosphorus metabolic processGO:00067931090.037
convergent extensionGO:00600261180.037
response to drugGO:004249330.037
cellular response to external stimulusGO:007149620.037
cognitionGO:005089010.037
regulation of protein targetingGO:190353320.037
cellular response to starvationGO:000926710.036
cellular carbohydrate metabolic processGO:004426240.036
positive regulation of map kinase activityGO:004340630.036
hormone transportGO:000991420.036
cortical cytoskeleton organizationGO:003086510.035
mitotic dna damage checkpointGO:004477340.035
protein targeting to nucleusGO:004474430.035
positive regulation of protein complex assemblyGO:003133420.035
gastrulationGO:00073692080.035
multicellular organism growthGO:003526440.035
protein localization to plasma membraneGO:007265910.035
regulation of signalingGO:00230512350.035
regulation of nitrogen compound metabolic processGO:00511712510.035
regulation of biological qualityGO:00650082630.034
negative regulation of cellular processGO:00485232830.034
regulation of hormone secretionGO:004688320.034
small molecule metabolic processGO:0044281770.034
Human
negative regulation of protein kinase activityGO:000646940.034
glucose importGO:004632320.034
peptide transportGO:001583310.033
regulation of multicellular organismal developmentGO:20000262230.033
digestive tract morphogenesisGO:00485462310.033
regionalizationGO:00030022740.033
positive regulation of secretionGO:005104710.032
hemopoiesisGO:00300971830.032
positive regulation of cellular catabolic processGO:003133130.032
embryonic organ morphogenesisGO:00485622740.032
amine metabolic processGO:000930820.031
response to stressGO:00069502630.031
establishment of protein localization to plasma membraneGO:009000210.031
positive regulation of catabolic processGO:000989640.031
cell morphogenesisGO:00009022890.031
nucleocytoplasmic transportGO:000691340.031
cellular protein modification processGO:00064641000.031
cellular response to extracellular stimulusGO:003166820.031
cell morphogenesis involved in neuron differentiationGO:00486671630.031
regulation of intracellular protein transportGO:003315730.031
regulation of signal transductionGO:00099662250.030
cellular biosynthetic processGO:00442492860.030
negative regulation of intracellular transportGO:003238730.030
regulation of response to nutrient levelsGO:003210710.030
oxoacid metabolic processGO:0043436310.030
sensory organ developmentGO:00074233930.030
regulation of cell communicationGO:00106462320.030
protein dephosphorylationGO:000647030.030
nuclear importGO:005117030.030
regulation of cellular ketone metabolic processGO:001056570.030
regulation of protein modification by small protein conjugation or removalGO:190332030.030
germ line stem cell maintenanceGO:003071820.030
membrane fusionGO:006102520.030
cellular aromatic compound metabolic processGO:00067252950.030
single organism membrane fusionGO:004480120.029
cellular macromolecule biosynthetic processGO:00346452240.029
microtubule organizing center organizationGO:003102310.029
carboxylic acid metabolic processGO:0019752220.029
hormone secretionGO:004687920.029
programmed cell deathGO:00125011190.029
meiotic nuclear divisionGO:000712640.029
phagocytosis engulfmentGO:000691110.028
regulation of extrinsic apoptotic signaling pathwayGO:200123630.028
determination of left right symmetryGO:00073681790.028
gene expressionGO:00104672520.028
determination of bilateral symmetryGO:00098552040.028
biosynthetic processGO:00090582940.028
regulation of nucleocytoplasmic transportGO:004682220.028
zymogen activationGO:003163830.028
central nervous system developmentGO:00074173870.027
regulation of cytokine productionGO:000181730.027
regulation of cellular carbohydrate metabolic processGO:001067540.027
negative regulation of cytoplasmic transportGO:190365020.027
stem cell divisionGO:001714510.027
positive regulation of cellular processGO:00485222010.027
cell cycleGO:0007049930.027
cell deathGO:00082191210.027
positive regulation of stress activated mapk cascadeGO:003287430.026
cellular response to nutrient levelsGO:003166920.026
glucose homeostasisGO:004259310.026
cytoskeleton dependent cytokinesisGO:006164030.026
membrane invaginationGO:001032410.026
rna metabolic processGO:00160702190.026
i kappab kinase nf kappab signalingGO:000724940.026
regulation of cell shapeGO:000836010.026
meiotic cell cycle processGO:190304630.026
regulation of glucose transportGO:001082710.026
cellular response to topologically incorrect proteinGO:003596720.026
cellular transition metal ion homeostasisGO:004691630.026
regulation of programmed cell deathGO:00430671010.025
spindle assemblyGO:005122520.025
negative regulation of protein transportGO:005122430.025
regulation of stem cell differentiationGO:200073640.025
phosphate containing compound metabolic processGO:00067961080.025
regulation of jun kinase activityGO:004350630.025
homeostatic processGO:00425921420.025
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.025
circadian sleep wake cycleGO:004274520.025
organic substance biosynthetic processGO:19015762890.025
centrosome cycleGO:000709810.025
centrosome organizationGO:005129710.025
negative regulation of mapk cascadeGO:004340940.025
negative regulation of nucleocytoplasmic transportGO:004682320.024
regulation of bindingGO:005109830.024
epithelial tube morphogenesisGO:00605621480.024
cell morphogenesis involved in differentiationGO:00009041950.024
cellular component assemblyGO:00226071700.024
response to topologically incorrect proteinGO:003596620.024
neuron projection developmentGO:00311751800.024
erk1 and erk2 cascadeGO:007037140.024
protein homooligomerizationGO:005126030.024
macromolecule biosynthetic processGO:00090592270.024
regulation of apoptotic processGO:0042981980.024
regulation of cellular biosynthetic processGO:00313262450.024
type b pancreatic cell developmentGO:000332340.024
organelle fusionGO:004828430.024
carbohydrate homeostasisGO:003350010.024
positive regulation of cellular component biogenesisGO:004408930.024
heterocycle biosynthetic processGO:00181302150.023
developmental growthGO:00485891660.023
regulation of anatomical structure morphogenesisGO:00226031300.023
adherens junction organizationGO:003433240.023
negative regulation of ras protein signal transductionGO:004658010.023
response to other organismGO:0051707970.023
cellular ketone metabolic processGO:0042180110.023
Human
deathGO:00162651210.023
cortical actin cytoskeleton organizationGO:003086610.023
immune system developmentGO:00025201910.023
regulation of erk1 and erk2 cascadeGO:007037240.023
nitrogen compound metabolic processGO:00068073190.023
Human
regulation of cellular amine metabolic processGO:003323800.022
negative regulation of tor signalingGO:003200720.022
response to uvGO:000941130.022
negative regulation of response to stimulusGO:00485851040.022
negative regulation of biological processGO:00485193040.022
organonitrogen compound metabolic processGO:1901564740.022
Human
response to external biotic stimulusGO:0043207970.022
nucleobase containing compound biosynthetic processGO:00346542050.022
response to organic substanceGO:00100331530.022
negative regulation of protein import into nucleusGO:004230820.022
regulation of cellular amino acid metabolic processGO:000652100.022
positive regulation of secretion by cellGO:190353210.022
positive regulation of cytokine productionGO:000181920.022
regulation of cell activationGO:005086510.022
nucleobase containing compound metabolic processGO:00061392740.022
regulation of circadian sleep wake cycle sleepGO:004518710.021
negative regulation of protein localization to nucleusGO:190018120.021
stem cell proliferationGO:007208940.021
regulation of protein catabolic processGO:004217610.021
response to corticosteroidGO:003196010.021
multi organism processGO:00517041340.021
positive regulation of erk1 and erk2 cascadeGO:007037420.021
regulation of glucose importGO:004632410.021
compound eye developmentGO:004874920.021
positive regulation of lipid metabolic processGO:004583410.021
endosome organizationGO:000703220.021
regulation of nucleotide catabolic processGO:003081120.021
regulation of protein ubiquitinationGO:003139630.021
cell projection organizationGO:00300302840.021
negative regulation of protein serine threonine kinase activityGO:007190120.020
regulation of meiotic cell cycleGO:005144510.020
gland developmentGO:00487321430.020
negative regulation of signalingGO:0023057960.020
regulation of cell differentiationGO:00455951420.020
intracellular signal transductionGO:0035556850.020
nucleic acid templated transcriptionGO:00976591810.020
response to glucoseGO:000974930.020
aromatic compound biosynthetic processGO:00194382170.020
positive regulation of jun kinase activityGO:004350720.020
regulation of protein localization to nucleusGO:190018020.020
regulation of nucleoside metabolic processGO:000911820.020
response to alkaloidGO:004327920.020
positive regulation of jnk cascadeGO:004633030.020
response to monosaccharideGO:003428430.020
regulation of purine nucleotide catabolic processGO:003312120.020
antimicrobial humoral responseGO:001973020.020
cell cycle g1 s phase transitionGO:004484310.020
cellular nitrogen compound metabolic processGO:00346412900.020
heart developmentGO:00075073130.019
response to nutrientGO:000758430.019
brain developmentGO:00074202930.019
transcription from rna polymerase ii promoterGO:0006366800.019
heterocycle metabolic processGO:00464832900.019
positive regulation of immune effector processGO:000269930.019
protein heterooligomerizationGO:005129110.019
neuron projection morphogenesisGO:00488121610.019
macromolecular complex assemblyGO:0065003350.019
regulation of growth rateGO:004000910.019
regulation of organelle assemblyGO:190211540.019
regulation of organ growthGO:004662030.019
circadian sleep wake cycle processGO:002241020.019
positive regulation of cell activationGO:005086710.019
tissue remodelingGO:004877140.019
locomotor rhythmGO:004547530.019
mitotic dna integrity checkpointGO:004477440.019
regulation of intracellular signal transductionGO:1902531570.019
regulation of carbohydrate metabolic processGO:000610940.019
ras protein signal transductionGO:000726570.019
regulation of nucleobase containing compound metabolic processGO:00192192500.019
regulation of cell developmentGO:00602841000.019
regulation of neural precursor cell proliferationGO:200017730.018
regulation of cell deathGO:00109411030.018
negative regulation of map kinase activityGO:004340720.018
regulation of reactive oxygen species metabolic processGO:200037720.018
negative regulation of catabolic processGO:000989530.018
locomotionGO:00400113130.018
organelle localizationGO:0051640490.018
negative regulation of cellular metabolic processGO:0031324770.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
centrosome duplicationGO:005129810.018
g1 s transition of mitotic cell cycleGO:000008210.018
phosphorylationGO:0016310690.018
synaptic vesicle transportGO:004848910.018
somatic muscle developmentGO:000752540.018
cellular protein metabolic processGO:00442671290.018
peptidyl lysine acetylationGO:001839420.018
development of primary female sexual characteristicsGO:004654540.018
regulation of macromolecule biosynthetic processGO:00105562250.018
small molecule catabolic processGO:004428230.018
cellular response to stressGO:0033554620.018
convergent extension involved in gastrulationGO:0060027710.018
protein modification processGO:00362111000.017
single organism cellular localizationGO:1902580460.017
peptidyl serine modificationGO:001820920.017
female sex differentiationGO:004666040.017
response to hydrogen peroxideGO:004254230.017
vesicle localizationGO:0051648270.017
regulation of autophagyGO:001050630.017
spermatid differentiationGO:004851520.017
regulation of localizationGO:00328791040.017
regulation of dendrite developmentGO:005077330.017
macromolecular complex subunit organizationGO:0043933740.017
positive regulation of cellular amine metabolic processGO:003324000.017
cellular response to lipopolysaccharideGO:007122230.017
adult behaviorGO:003053420.017
ribonucleoside monophosphate catabolic processGO:000915840.017
immune system processGO:00023762410.017
pole plasm assemblyGO:000731540.017
regulation of rna biosynthetic processGO:20011412130.017
protein complex biogenesisGO:0070271300.017
positive regulation of translationGO:004572710.017
ear developmentGO:00435831270.017
response to amino acidGO:004320020.017
positive regulation of cell adhesionGO:004578510.017
negative regulation of nuclear divisionGO:005178430.017
regulation of reproductive processGO:200024140.017
protein complex assemblyGO:0006461300.017
regulation of protein bindingGO:004339330.017
positive regulation of apoptotic signaling pathwayGO:200123510.017
eye developmentGO:00016542770.017
regulation of synapse organizationGO:005080730.017
developmental programmed cell deathGO:001062340.016
establishment of localization in cellGO:0051649770.016
protein stabilizationGO:005082120.016
regulation of jak stat cascadeGO:004642530.016
negative regulation of cell communicationGO:0010648960.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
positive regulation of protein kinase b signalingGO:005189710.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
anterior posterior pattern specificationGO:00099521520.016
positive regulation of i kappab kinase nf kappab signalingGO:004312330.016
hepaticobiliary system developmentGO:0061008980.016
circadian sleep wake cycle sleepGO:005080210.016
protein polyubiquitinationGO:000020940.016
regulation of tube sizeGO:003515020.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
regulation of synaptic plasticityGO:004816710.016
response to abiotic stimulusGO:00096281220.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.016
cell cell signalingGO:0007267520.016
chemosensory behaviorGO:000763510.016
macroautophagyGO:001623610.016
regulation of blood vessel sizeGO:005088020.016
negative regulation of synapse assemblyGO:005196420.016
positive regulation of dna metabolic processGO:005105410.016
regulation of response to extracellular stimulusGO:003210410.016
carbohydrate biosynthetic processGO:001605110.016
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.016
response to hexoseGO:000974630.016
interspecies interaction between organismsGO:004441940.016
mononuclear cell proliferationGO:003294310.016
regulation of collateral sprouting in absence of injuryGO:004869640.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
skeletal system developmentGO:00015011810.016
cellular localizationGO:0051641970.016
b cell activationGO:004211320.016
negative regulation of intracellular protein transportGO:009031730.016
er nucleus signaling pathwayGO:000698420.016
head developmentGO:00603223030.016
catecholamine metabolic processGO:000658420.016
exocytosisGO:000688710.016
embryo development ending in birth or egg hatchingGO:00097922710.015
organic substance transportGO:0071702580.015
positive regulation of cellular metabolic processGO:0031325940.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
cellular respirationGO:004533330.015
protein acylationGO:004354330.015
muscle structure developmentGO:00610611960.015
response to biotic stimulusGO:0009607970.015
cell substrate adhesionGO:003158940.015
positive regulation of cellular carbohydrate metabolic processGO:001067610.015
protein acetylationGO:000647320.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
macromolecule modificationGO:00434121110.015
fatty acid catabolic processGO:000906210.015
cell agingGO:000756920.015
dna templated transcription initiationGO:000635210.015
activation of mapk activityGO:000018730.015
regulation of biosynthetic processGO:00098892500.015
regulation of protein localization to plasma membraneGO:190307610.015
apoptotic process involved in developmentGO:190274220.015
axonogenesisGO:00074091520.014
hormone biosynthetic processGO:004244630.014
transcription dna templatedGO:00063511810.014
glycoprotein metabolic processGO:0009100230.014
energy reserve metabolic processGO:000611220.014
actin polymerization or depolymerizationGO:000815420.014
regulation of inflammatory responseGO:005072720.014
regulation of gtp catabolic processGO:003312420.014
pigmentationGO:0043473850.014
olfactory lobe developmentGO:002198840.014
cellular component movementGO:00069283350.014
entrainment of circadian clockGO:000964920.014
protein phosphorylationGO:0006468470.014
viral processGO:001603210.014
small gtpase mediated signal transductionGO:000726480.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
photoreceptor cell differentiationGO:0046530550.014
positive regulation of gtpase activityGO:004354710.014
female gonad developmentGO:000858540.014
catechol containing compound metabolic processGO:000971220.014
regulation of cellular component organizationGO:0051128860.014
regulation of metal ion transportGO:001095940.014
synaptic growth at neuromuscular junctionGO:005112420.014
mitochondrial transportGO:000683920.014
striated muscle cell differentiationGO:00511461290.014
cellular response to organic substanceGO:00713101050.014
regulation of dendrite morphogenesisGO:004881430.014
localization of cellGO:00516742440.014
neuroblast proliferationGO:000740520.014
negative regulation of metabolic processGO:0009892860.014
positive regulation of nucleotide catabolic processGO:003081310.014
myeloid cell differentiationGO:0030099860.014
regulation of synapse assemblyGO:005196330.014
system processGO:00030081850.014
cell motilityGO:00488702440.014
liver developmentGO:0001889960.014
cellular amino acid metabolic processGO:000652070.013
cellular response to chemical stimulusGO:00708871570.013
secondary metabolic processGO:001974830.013
cellular response to biotic stimulusGO:007121630.013
positive regulation of cytoskeleton organizationGO:005149530.013
toxin metabolic processGO:000940410.013
sensory perception of chemical stimulusGO:000760630.013
fatty acid biosynthetic processGO:000663340.013
regulation of blood pressureGO:000821710.013
internal protein amino acid acetylationGO:000647520.013
meiosis iGO:000712710.013
rna localizationGO:000640340.013
regulation of gene expressionGO:00104682650.013
cellular monovalent inorganic cation homeostasisGO:003000420.013
regulation of transcription dna templatedGO:00063552130.013
negative regulation of macromolecule metabolic processGO:0010605760.013
response to endogenous stimulusGO:0009719830.013
neurotransmitter secretionGO:000726920.013
single organism biosynthetic processGO:0044711710.013
purine nucleoside monophosphate catabolic processGO:000912840.013
regulation of growthGO:0040008420.013
protein n linked glycosylationGO:000648710.013
inner ear developmentGO:00488391260.013
organic cyclic compound biosynthetic processGO:19013622230.013
response to carbohydrateGO:000974330.013
positive regulation of inflammatory responseGO:005072910.013
vasculature developmentGO:00019442780.013
regulation of dna replicationGO:000627530.013
positive regulation of carbohydrate metabolic processGO:004591310.013
mitotic cytokinesisGO:000028130.013
hypothalamus cell differentiationGO:002197940.013
response to coldGO:000940940.013
dorsal ventral pattern formationGO:00099531250.013
post embryonic organ developmentGO:004856940.013
chemical homeostasisGO:0048878490.013
specification of symmetryGO:00097992040.013
defense response to other organismGO:0098542330.012
positive regulation of muscle organ developmentGO:004863610.012
rna biosynthetic processGO:00327741810.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
positive regulation of histone modificationGO:003105810.012
positive regulation of cell divisionGO:005178120.012
regulation of stem cell proliferationGO:007209120.012
organic acid catabolic processGO:001605430.012
lateral inhibitionGO:004633110.012
sequestering of metal ionGO:005123830.012
neurotransmitter transportGO:000683620.012
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.012
long chain fatty acid metabolic processGO:000167610.012
regulation of transporter activityGO:003240920.012

kdsr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
disease of metabolismDOID:001466700.029
inherited metabolic disorderDOID:65500.029
disease of cellular proliferationDOID:1456600.018
nervous system diseaseDOID:86300.017
eye diseaseDOID:561400.017
eye and adnexa diseaseDOID:149200.017
sensory system diseaseDOID:005015500.017
lysosomal storage diseaseDOID:321100.016
organ system cancerDOID:005068600.015
cancerDOID:16200.015