Danio rerio

0 known processes

polr2d

polymerase (RNA) II (DNA directed) polypeptide D

(Aliases: wu:fa95b11,zgc:110435)

polr2d biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nitrogen compound metabolic processGO:00068073190.679
biosynthetic processGO:00090582940.593
response to metal ionGO:0010038340.550
estrogen metabolic processGO:000821020.511
larval developmentGO:000216420.507
embryonic heart tube developmentGO:00350501330.397
negative regulation of biological processGO:00485193040.373
cellular macromolecule metabolic processGO:00442603910.370
regulation of biological qualityGO:00650082630.367
heart developmentGO:00075073130.364
response to chemicalGO:00422213200.322
heart morphogenesisGO:00030071560.296
diterpenoid metabolic processGO:0016101150.295
regulation of response to stimulusGO:00485832690.291
appendage morphogenesisGO:0035107560.285
central nervous system developmentGO:00074173870.279
tube morphogenesisGO:00352393490.273
sensory organ developmentGO:00074233930.269
head developmentGO:00603223030.262
guanosine containing compound catabolic processGO:190106920.260
cellular biosynthetic processGO:00442492860.259
organic cyclic compound biosynthetic processGO:19013622230.245
regulation of metabolic processGO:00192223590.242
gene expressionGO:00104672520.238
cellular nitrogen compound metabolic processGO:00346412900.235
regulation of cell killingGO:003134120.231
iron ion homeostasisGO:005507240.207
response to drugGO:004249330.201
negative regulation of cellular processGO:00485232830.180
cellular component biogenesisGO:00440851780.178
vitamin a biosynthetic processGO:003523810.177
agingGO:000756820.176
nucleobase containing compound biosynthetic processGO:00346542050.172
mesenchyme developmentGO:00604851270.169
regulation of cellular metabolic processGO:00313233200.167
organic substance biosynthetic processGO:19015762890.167
digestive tract developmentGO:00485652650.163
cell morphogenesis involved in differentiationGO:00009041950.163
cellular aldehyde metabolic processGO:000608140.162
homeostatic processGO:00425921420.154
hormone biosynthetic processGO:004244630.150
response to cadmium ionGO:0046686140.149
fin morphogenesisGO:0033334530.145
organic cyclic compound metabolic processGO:19013603010.144
cellular aromatic compound metabolic processGO:00067252950.141
system processGO:00030081850.140
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.138
cellular response to chemical stimulusGO:00708871570.136
response to bacteriumGO:0009617580.134
embryonic organ developmentGO:00485683810.134
embryonic cranial skeleton morphogenesisGO:0048701900.132
camera type eye developmentGO:00430102220.130
retina development in camera type eyeGO:00600411460.127
maintenance of locationGO:005123540.126
generation of neuronsGO:00486993850.124
establishment of protein localization to plasma membraneGO:009000210.124
fat soluble vitamin biosynthetic processGO:004236220.123
oxidation reduction processGO:0055114410.123
regulation of multicellular organismal processGO:00512392770.122
fin developmentGO:0033333770.121
nucleoside monophosphate catabolic processGO:000912540.119
cellular component morphogenesisGO:00329893360.117
stem cell differentiationGO:00488631170.117
response to organic substanceGO:00100331530.116
embryo development ending in birth or egg hatchingGO:00097922710.115
digestive system developmentGO:00551232890.113
cellular localizationGO:0051641970.110
positive regulation of lymphocyte mediated immunityGO:000270810.109
gastrulationGO:00073692080.108
response to stressGO:00069502630.108
mesenchymal cell differentiationGO:0048762870.105
cytokinetic processGO:003250620.105
embryonic organ morphogenesisGO:00485622740.105
lipid storageGO:001991510.104
neural crest cell developmentGO:0014032620.100
transportGO:00068102200.100
brain developmentGO:00074202930.099
establishment of protein localization to organelleGO:007259440.099
establishment of localization in cellGO:0051649770.099
organelle fusionGO:004828430.098
guanosine containing compound metabolic processGO:190106840.098
nucleobase containing compound metabolic processGO:00061392740.097
response to nutrientGO:000758430.096
cellular hormone metabolic processGO:0034754190.096
negative regulation of kinase activityGO:003367340.095
positive regulation of transportGO:005105020.095
neural crest cell differentiationGO:0014033720.095
leukocyte mediated immunityGO:000244360.093
phosphorus metabolic processGO:00067931090.092
positive regulation of leukocyte mediated cytotoxicityGO:000191210.090
membrane fusionGO:006102520.090
regulation of translational initiationGO:000644610.089
immune effector processGO:0002252230.089
embryonic heart tube morphogenesisGO:00031431080.086
terpenoid metabolic processGO:0006721150.086
regulation of synaptic plasticityGO:004816710.086
digestive tract morphogenesisGO:00485462310.085
mononuclear cell proliferationGO:003294310.083
positive regulation of cell killingGO:003134320.082
single organism metabolic processGO:00447102170.082
embryonic skeletal system morphogenesisGO:0048704930.080
pancreas developmentGO:0031016840.080
appendage developmentGO:0048736800.080
vitamin a metabolic processGO:000677610.078
skeletal system developmentGO:00015011810.078
single organism transportGO:00447652060.078
programmed cell deathGO:00125011190.077
positive regulation of biological processGO:00485182530.077
mesenchymal cell developmentGO:0014031780.076
small molecule metabolic processGO:0044281770.074
fat soluble vitamin metabolic processGO:000677540.074
organophosphate metabolic processGO:0019637370.074
cellular macromolecule biosynthetic processGO:00346452240.073
eye developmentGO:00016542770.072
protein acetylationGO:000647320.072
cellular nitrogen compound biosynthetic processGO:00442712180.071
response to lipidGO:0033993600.071
regulation of leukocyte mediated immunityGO:000270310.070
cell killingGO:000190620.070
negative regulation of reproductive processGO:200024230.069
determination of bilateral symmetryGO:00098552040.069
response to inorganic substanceGO:0010035380.068
purine ribonucleoside monophosphate catabolic processGO:000916940.068
single organism biosynthetic processGO:0044711710.068
aromatic compound biosynthetic processGO:00194382170.068
protein localization to nucleusGO:003450430.067
heterocycle metabolic processGO:00464832900.066
rna metabolic processGO:00160702190.066
amine metabolic processGO:000930820.065
single organism localizationGO:19025782250.065
nucleocytoplasmic transportGO:000691340.065
regulation of gene expressionGO:00104682650.064
notch signaling pathwayGO:0007219350.063
deathGO:00162651210.062
growthGO:00400071740.062
carbohydrate derivative biosynthetic processGO:1901137430.060
chordate embryonic developmentGO:00430092710.060
respiratory electron transport chainGO:002290420.060
retinoid metabolic processGO:0001523150.059
regulation of cellular amine metabolic processGO:003323800.058
protein import into nucleusGO:000660630.057
hormone metabolic processGO:0042445190.057
pronuclear migrationGO:003504610.057
regulation of protein targetingGO:190353320.057
regulation of reproductive processGO:200024140.056
heterocycle biosynthetic processGO:00181302150.055
embryonic skeletal system developmentGO:0048706970.055
positive regulation of gtp catabolic processGO:003312610.055
inner ear developmentGO:00488391260.053
retina homeostasisGO:0001895120.052
neuron differentiationGO:00301823530.052
regulation of primary metabolic processGO:00800903110.052
establishment or maintenance of apical basal cell polarityGO:0035088120.052
striated muscle tissue developmentGO:00147061100.051
cell proliferationGO:0008283800.051
eye morphogenesisGO:00485921440.051
internal protein amino acid acetylationGO:000647520.051
cell surface receptor signaling pathwayGO:00071663250.051
translational initiationGO:000641330.050
regulation of protein transportGO:005122330.050
regulation of leukocyte mediated cytotoxicityGO:000191010.050
hatchingGO:003518840.050
pectoral fin morphogenesisGO:0035138290.049
phosphate containing compound metabolic processGO:00067961080.049
behaviorGO:0007610740.049
positive regulation of leukocyte mediated immunityGO:000270510.049
reactive oxygen species biosynthetic processGO:190340910.049
response to biotic stimulusGO:0009607970.049
regulation of meiotic cell cycleGO:005144510.049
positive regulation of immune effector processGO:000269930.049
ribonucleoside monophosphate catabolic processGO:000915840.049
negative regulation of apoptotic processGO:0043066550.048
mrna metabolic processGO:0016071200.048
heart contractionGO:0060047710.048
determination of left right symmetryGO:00073681790.047
signal transductionGO:00071654550.047
gtp metabolic processGO:004603940.046
regulation of nucleocytoplasmic transportGO:004682220.045
pectoral fin developmentGO:0033339500.045
determination of heart left right asymmetryGO:00613711170.045
fertilizationGO:000956630.045
immune system processGO:00023762410.045
organonitrogen compound biosynthetic processGO:1901566470.045
single organism nuclear importGO:190259330.045
cell morphogenesis involved in neuron differentiationGO:00486671630.044
cellular response to nutrient levelsGO:003166920.044
meiotic nuclear divisionGO:000712640.044
regulation of protein import into nucleusGO:004230620.043
response to oxygen containing compoundGO:1901700550.043
protein importGO:001703830.043
cellular protein metabolic processGO:00442671290.043
single organism membrane fusionGO:004480120.043
negative regulation of protein kinase activityGO:000646940.042
cell part morphogenesisGO:00329902460.042
positive regulation of cellular processGO:00485222010.041
protein secretionGO:000930610.041
leukocyte proliferationGO:007066110.041
cellular component assemblyGO:00226071700.041
t cell mediated immunityGO:000245610.040
response to other organismGO:0051707970.040
purine containing compound biosynthetic processGO:0072522200.040
stem cell proliferationGO:007208940.040
alcohol metabolic processGO:0006066110.040
protein metabolic processGO:00195381830.039
regulation of intracellular protein transportGO:003315730.039
negative regulation of catabolic processGO:000989530.039
modification dependent macromolecule catabolic processGO:004363230.039
immune system developmentGO:00025201910.039
response to unfolded proteinGO:000698620.039
macromolecule biosynthetic processGO:00090592270.039
cell projection morphogenesisGO:00488582440.039
nuclear transportGO:005116940.039
morphogenesis of an epitheliumGO:00020093330.038
protein acylationGO:004354330.038
xenobiotic metabolic processGO:000680540.038
epithelial cell differentiationGO:00308551160.038
cytoskeleton dependent cytokinesisGO:006164030.038
cellular response to external stimulusGO:007149620.038
isoprenoid biosynthetic processGO:000829970.038
t cell differentiationGO:003021760.038
cellular amine metabolic processGO:004410620.037
nuclear importGO:005117030.037
immunoglobulin mediated immune responseGO:001606430.037
regulation of establishment of protein localizationGO:007020140.036
purine nucleoside monophosphate catabolic processGO:000912840.036
cellular lipid metabolic processGO:0044255360.036
nuclear exportGO:005116810.036
positive regulation of cellular catabolic processGO:003133130.036
androgen metabolic processGO:000820920.035
specification of symmetryGO:00097992040.035
regulation of developmental processGO:00507932470.035
embryonic viscerocranium morphogenesisGO:0048703520.035
regulation of cell differentiationGO:00455951420.035
single fertilizationGO:000733830.035
sensory organ morphogenesisGO:00905962000.035
response to vitaminGO:003327330.035
cation homeostasisGO:0055080330.035
heart loopingGO:0001947940.034
response to corticosteroidGO:003196010.033
gtp catabolic processGO:000618420.033
reactive nitrogen species metabolic processGO:200105700.033
rna biosynthetic processGO:00327741810.033
lymphocyte mediated immunityGO:000244950.033
negative regulation of cell differentiationGO:0045596460.033
negative regulation of translationGO:001714810.032
response to topologically incorrect proteinGO:003596620.032
single organism behaviorGO:0044708240.032
cell activationGO:0001775160.032
regulation of nitrogen compound metabolic processGO:00511712510.032
regulation of bindingGO:005109830.032
regulation of protein localization to nucleusGO:190018020.032
regulation of cytoplasmic transportGO:190364940.032
g1 s transition of mitotic cell cycleGO:000008210.031
embryonic pectoral fin morphogenesisGO:0035118240.031
long chain fatty acid biosynthetic processGO:004275910.031
stem cell maintenanceGO:001982740.031
purine containing compound metabolic processGO:0072521290.031
vasculature developmentGO:00019442780.031
nucleic acid metabolic processGO:00903042440.030
retinal metabolic processGO:004257430.030
regulation of synapse assemblyGO:005196330.030
sensory perception of chemical stimulusGO:000760630.030
hematopoietic or lymphoid organ developmentGO:00485341910.030
multicellular organismal response to stressGO:003355520.030
neural nucleus developmentGO:0048857150.030
heart processGO:0003015710.030
cellular response to organic cyclic compoundGO:0071407380.030
homeostasis of number of cellsGO:0048872620.029
centrosome cycleGO:000709810.029
regulation of cell deathGO:00109411030.029
diterpenoid biosynthetic processGO:001610270.029
negative regulation of protein phosphorylationGO:000193340.029
protein localization to plasma membraneGO:007265910.028
mrna catabolic processGO:000640260.028
positive regulation of purine nucleotide catabolic processGO:003312310.028
androgen biosynthetic processGO:000670210.028
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.028
purine ribonucleoside biosynthetic processGO:004612920.028
formation of primary germ layerGO:0001704620.028
neurological system processGO:0050877620.028
regulation of inflammatory responseGO:005072720.028
cell cycle g1 s phase transitionGO:004484310.028
regulation of synapse organizationGO:005080730.028
cognitionGO:005089010.028
nitric oxide biosynthetic processGO:000680920.028
peptidyl serine phosphorylationGO:001810510.027
defense responseGO:0006952470.027
cellular response to organic substanceGO:00713101050.027
endocrine system developmentGO:0035270650.027
regulation of synaptic growth at neuromuscular junctionGO:000858210.027
golgi vesicle transportGO:004819330.027
chemical homeostasisGO:0048878490.027
response to abiotic stimulusGO:00096281220.027
organonitrogen compound metabolic processGO:1901564740.027
rna catabolic processGO:000640170.027
transcription from rna polymerase ii promoterGO:0006366800.027
lymphocyte proliferationGO:004665110.027
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.027
regulation of macromolecule metabolic processGO:00602553170.027
muscle structure developmentGO:00610611960.026
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.026
locomotionGO:00400113130.026
positive regulation of catabolic processGO:000989640.026
vitamin metabolic processGO:0006766110.026
muscle cell developmentGO:00550011150.026
developmental growthGO:00485891660.026
protein targeting to nucleusGO:004474430.026
positive regulation of cell cycleGO:004578730.026
positive regulation of biosynthetic processGO:0009891680.026
b cell activationGO:004211320.026
bone developmentGO:0060348140.026
hemopoiesisGO:00300971830.026
regulation of multicellular organismal developmentGO:20000262230.026
cellular response to stressGO:0033554620.025
mitotic dna integrity checkpointGO:004477440.025
tissue homeostasisGO:0001894250.025
response to acid chemicalGO:0001101170.025
positive regulation of metabolic processGO:00098931080.025
centrosome organizationGO:005129710.025
actin cytoskeleton organizationGO:0030036630.025
positive regulation of interferon beta productionGO:003272810.025
response to endogenous stimulusGO:0009719830.025
peptide metabolic processGO:000651810.025
ion homeostasisGO:0050801410.025
skeletal system morphogenesisGO:00487051020.024
intracellular signal transductionGO:0035556850.024
cell agingGO:000756920.024
anatomical structure homeostasisGO:0060249360.024
regulation of calcium ion transportGO:005192420.024
transition metal ion homeostasisGO:005507650.024
positive regulation of cellular amine metabolic processGO:003324000.024
negative regulation of developmental processGO:0051093650.024
regulation of cellular biosynthetic processGO:00313262450.024
modification dependent protein catabolic processGO:001994130.023
microtubule organizing center organizationGO:003102310.023
striated muscle cell developmentGO:00550021080.023
negative regulation of autophagyGO:001050710.023
adult behaviorGO:003053420.023
cell motilityGO:00488702440.023
regulation of purine nucleotide catabolic processGO:003312120.023
cellular response to biotic stimulusGO:007121630.023
leukocyte mediated cytotoxicityGO:000190910.023
posttranscriptional gene silencingGO:001644130.023
cell cycleGO:0007049930.023
multicellular organismal homeostasisGO:0048871290.022
regulation of multicellular organism growthGO:004001440.022
regulation of nucleic acid templated transcriptionGO:19035062130.022
cytokinesisGO:000091030.022
endocrine pancreas developmentGO:0031018270.022
transcription dna templatedGO:00063511810.022
response to molecule of bacterial originGO:0002237140.022
muscle organ developmentGO:00075171010.022
oxoacid metabolic processGO:0043436310.022
positive regulation of jnk cascadeGO:004633030.022
cell morphogenesisGO:00009022890.022
aromatic compound catabolic processGO:0019439150.022
cytoplasm organizationGO:000702840.022
primary neural tube formationGO:001402010.022
lateral line developmentGO:0048882660.022
nucleic acid templated transcriptionGO:00976591810.021
vitamin biosynthetic processGO:000911020.021
regulation of gtp catabolic processGO:003312420.021
rna localizationGO:000640340.021
metal ion homeostasisGO:0055065260.021
localization of cellGO:00516742440.021
positive regulation of neural precursor cell proliferationGO:200017910.021
lipid oxidationGO:003444010.021
regulation of i kappab kinase nf kappab signalingGO:004312240.021
lipid biosynthetic processGO:0008610220.021
response to external biotic stimulusGO:0043207970.021
mrna processingGO:0006397140.021
carboxylic acid catabolic processGO:004639530.021
multicellular organism growthGO:003526440.021
embryonic appendage morphogenesisGO:0035113300.021
nitric oxide metabolic processGO:004620920.020
blood circulationGO:0008015870.020
isoprenoid metabolic processGO:0006720150.020
mitotic cell cycle processGO:1903047480.020
regulation of cytokine productionGO:000181730.020
phagocytosisGO:000690930.020
positive regulation of cell activationGO:005086710.020
energy reserve metabolic processGO:000611220.020
ubiquitin dependent protein catabolic processGO:000651130.020
negative regulation of macromolecule biosynthetic processGO:0010558480.020
response to external stimulusGO:00096052640.020
cellular protein catabolic processGO:004425740.020
small molecule biosynthetic processGO:0044283160.020
negative regulation of cellular protein metabolic processGO:0032269160.019
gene silencing by rnaGO:003104740.019
regulation of molecular functionGO:0065009700.019
negative regulation of multicellular organismal processGO:0051241690.019
atp synthesis coupled electron transportGO:004277310.019
peptidyl serine modificationGO:001820920.019
cellular response to extracellular stimulusGO:003166820.019
protein complex localizationGO:003150310.019
thermosensory behaviorGO:004004010.019
rna transportGO:005065820.019
rna 3 end processingGO:003112320.019
response to retinoic acidGO:003252660.019
regulation of response to nutrient levelsGO:003210710.019
protein complex biogenesisGO:0070271300.018
small molecule catabolic processGO:004428230.018
eye photoreceptor cell differentiationGO:0001754450.018
carboxylic acid metabolic processGO:0019752220.018
protein homooligomerizationGO:005126030.018
regulation of nucleoside metabolic processGO:000911820.018
sensory perception of painGO:001923310.018
leukocyte activationGO:0045321120.018
regulation of apoptotic processGO:0042981980.018
mrna 3 end processingGO:003112420.018
regulation of catalytic activityGO:0050790550.018
steroid biosynthetic processGO:000669450.018
regulation of cellular amino acid metabolic processGO:000652100.018
stem cell divisionGO:001714510.018
primary alcohol metabolic processGO:003430870.018
organic acid metabolic processGO:0006082310.018
cellular carbohydrate metabolic processGO:004426240.018
regulation of protein ubiquitinationGO:003139630.018
establishment of localizationGO:00512342440.017
establishment of vesicle localizationGO:0051650240.017
regulation of cellular protein metabolic processGO:0032268520.017
cellular extravasationGO:004512310.017
mrna cleavage involved in gene silencing by mirnaGO:003527910.017
blood vessel morphogenesisGO:00485142160.017
apoptotic process involved in developmentGO:190274220.017
cellular catabolic processGO:0044248270.017
regulation of programmed cell deathGO:00430671010.017
circulatory system processGO:0003013870.017
muscle tissue developmentGO:00605371100.017
negative regulation of cytokine productionGO:000181810.017
regulation of biosynthetic processGO:00098892500.017
regulation of cell activationGO:005086510.017
exocrine pancreas developmentGO:0031017280.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
response to organic cyclic compoundGO:0014070510.017
negative regulation of protein serine threonine kinase activityGO:007190120.017
response to steroid hormoneGO:0048545350.017
autophagyGO:000691440.016
activation of mapk activityGO:000018730.016
organelle organizationGO:00069962270.016
response to woundingGO:00096111160.016
regulation of gtpase activityGO:004308720.016
lymphocyte activationGO:0046649100.016
ear developmentGO:00435831270.016
catechol containing compound metabolic processGO:000971220.016
cellular amide metabolic processGO:004360340.016
response to amphetamineGO:000197510.016
response to amineGO:001407510.016
membrane lipid biosynthetic processGO:004646720.016
positive regulation of stress activated mapk cascadeGO:003287430.016
ribonucleoside metabolic processGO:0009119110.016
adaptive immune responseGO:000225050.016
g2 dna damage checkpointGO:003157230.015
cellular component movementGO:00069283350.015
blood coagulationGO:0007596120.015
negative regulation of cellular catabolic processGO:003133030.015
cellular response to starvationGO:000926710.015
negative regulation of gene expressionGO:0010629650.015
cellular ketone metabolic processGO:0042180110.015
reproductionGO:0000003400.015
cellular response to topologically incorrect proteinGO:003596720.015
sensory system developmentGO:0048880760.015
macromolecule modificationGO:00434121110.015
negative regulation of intracellular protein transportGO:009031730.015
organelle localizationGO:0051640490.015
long chain fatty acid metabolic processGO:000167610.015
positive regulation of rna metabolic processGO:0051254590.015
regulation of neural precursor cell proliferationGO:200017730.015
chemosensory behaviorGO:000763510.015
regulation of metal ion transportGO:001095940.015
axonogenesisGO:00074091520.015
carbohydrate derivative metabolic processGO:1901135610.015
catecholamine metabolic processGO:000658420.015
rna polyadenylationGO:004363120.015
regulation of cell developmentGO:00602841000.015
synaptic vesicle transportGO:004848910.015
oocyte anterior posterior axis specificationGO:000731440.015
negative regulation of cell communicationGO:0010648960.015
response to nitrogen compoundGO:1901698190.015
forebrain developmentGO:0030900960.015

polr2d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
myopathyDOID:42300.053
muscle tissue diseaseDOID:6600.053
disease of anatomical entityDOID:700.053
musculoskeletal system diseaseDOID:1700.053
muscular diseaseDOID:008000000.053
cardiovascular system diseaseDOID:128700.053
heart diseaseDOID:11400.053
cardiomyopathyDOID:005070000.053
disease of metabolismDOID:001466700.050
intrinsic cardiomyopathyDOID:006003600.045
organ system cancerDOID:005068600.038
cancerDOID:16200.038
disease of cellular proliferationDOID:1456600.038
nervous system diseaseDOID:86300.023
mitochondrial metabolism diseaseDOID:70000.022
inherited metabolic disorderDOID:65500.022