Danio rerio

0 known processes

polr2a

polymerase (RNA) II (DNA directed) polypeptide A

(Aliases: im:7136071)

polr2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular nitrogen compound metabolic processGO:00346412900.228
meiotic chromosome segregationGO:004513230.180
cellular component assemblyGO:00226071700.178
cellular component biogenesisGO:00440851780.176
sensory organ developmentGO:00074233930.154
signal transductionGO:00071654550.135
cognitionGO:005089010.132
regulation of transcription from rna polymerase ii promoterGO:00063571140.131
hemopoiesisGO:00300971830.123
regulation of organelle assemblyGO:190211540.121
immune system developmentGO:00025201910.117
immune system processGO:00023762410.116
single organism organelle organizationGO:19025891990.115
determination of bilateral symmetryGO:00098552040.110
translational initiationGO:000641330.101
cellular component movementGO:00069283350.098
blood vessel morphogenesisGO:00485142160.095
negative regulation of cellular processGO:00485232830.092
nucleocytoplasmic transportGO:000691340.090
maintenance of locationGO:005123540.087
organelle organizationGO:00069962270.085
protein importGO:001703830.085
spindle assemblyGO:005122520.084
meiosis iGO:000712710.081
regulation of nucleocytoplasmic transportGO:004682220.081
peptide transportGO:001583310.080
embryonic organ developmentGO:00485683810.077
regulation of translational initiationGO:000644610.076
gene expressionGO:00104672520.072
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.072
embryo development ending in birth or egg hatchingGO:00097922710.072
regulation of synaptic plasticityGO:004816710.072
nuclear transportGO:005116940.071
specification of symmetryGO:00097992040.070
cell migrationGO:00164772370.070
regulation of intracellular protein transportGO:003315730.069
heterocycle metabolic processGO:00464832900.068
negative regulation of nucleocytoplasmic transportGO:004682320.068
cell motilityGO:00488702440.067
multicellular organism growthGO:003526440.067
regulation of multicellular organism growthGO:004001440.065
oocyte anterior posterior axis specificationGO:000731440.065
protein dephosphorylationGO:000647030.064
macromolecule biosynthetic processGO:00090592270.064
regulation of protein targetingGO:190353320.064
camera type eye developmentGO:00430102220.063
regulation of synaptic growth at neuromuscular junctionGO:000858210.063
meiotic cell cycle processGO:190304630.063
positive regulation of biological processGO:00485182530.063
mesoderm developmentGO:0007498880.060
locomotor rhythmGO:004547530.060
positive regulation of transportGO:005105020.058
positive regulation of cellular catabolic processGO:003133130.057
cellular amide metabolic processGO:004360340.056
tube morphogenesisGO:00352393490.056
cellular response to nutrient levelsGO:003166920.054
cellular macromolecule metabolic processGO:00442603910.054
negative regulation of biological processGO:00485193040.053
regulation of signal transductionGO:00099662250.053
regulation of biological qualityGO:00650082630.052
cytokinesisGO:000091030.052
pole plasm assemblyGO:000731540.052
chordate embryonic developmentGO:00430092710.051
developmental growthGO:00485891660.051
regulation of gene expressionGO:00104682650.051
steroid hormone secretionGO:003592910.050
germ line stem cell divisionGO:004207810.050
meiotic nuclear divisionGO:000712640.049
stem cell maintenanceGO:001982740.048
regulation of establishment of protein localizationGO:007020140.046
regulation of signalingGO:00230512350.046
hormone secretionGO:004687920.046
digestive tract developmentGO:00485652650.045
retina development in camera type eyeGO:00600411460.045
skeletal system developmentGO:00015011810.045
establishment of protein localization to organelleGO:007259440.045
intracellular signal transductionGO:0035556850.045
cellular modified amino acid metabolic processGO:000657530.044
organelle assemblyGO:00709251100.044
embryonic cranial skeleton morphogenesisGO:0048701900.044
mitotic cell cycle processGO:1903047480.043
mitotic cell cycleGO:0000278640.043
angiogenesisGO:00015251580.042
regulation of protein transportGO:005122330.042
nitrogen compound metabolic processGO:00068073190.042
regulation of multicellular organismal processGO:00512392770.042
regulation of alternative mrna splicing via spliceosomeGO:000038110.042
synaptic vesicle localizationGO:009747910.042
organism emergence from protective structureGO:007168440.041
maternal determination of anterior posterior axis embryoGO:000835840.041
regulation of nitrogen compound metabolic processGO:00511712510.041
negative regulation of signalingGO:0023057960.041
cartilage developmentGO:0051216960.040
protein import into nucleusGO:000660630.040
heterocycle biosynthetic processGO:00181302150.040
skeletal system morphogenesisGO:00487051020.039
synaptic vesicle transportGO:004848910.039
cellular response to extracellular stimulusGO:003166820.039
regulation of bindingGO:005109830.039
eye developmentGO:00016542770.039
modification dependent macromolecule catabolic processGO:004363230.039
regulation of synapse organizationGO:005080730.039
macromolecular complex subunit organizationGO:0043933740.039
fin regenerationGO:0031101510.038
positive regulation of signal transductionGO:0009967560.037
organic cyclic compound metabolic processGO:19013603010.036
circadian regulation of gene expressionGO:003292280.036
blood vessel developmentGO:00015682460.036
transcription from rna polymerase ii promoterGO:0006366800.036
epithelial tube morphogenesisGO:00605621480.036
organic substance biosynthetic processGO:19015762890.035
negative regulation of cytoplasmic transportGO:190365020.035
regulation of macromolecule biosynthetic processGO:00105562250.035
regulation of circadian rhythmGO:004275240.035
nucleic acid templated transcriptionGO:00976591810.035
regulation of stem cell differentiationGO:200073640.035
single organism nuclear importGO:190259330.035
regulation of mrna processingGO:005068430.035
locomotionGO:00400113130.034
positive regulation of cellular component biogenesisGO:004408930.034
regulation of cell communicationGO:00106462320.034
regulation of cytoplasmic transportGO:190364940.034
localization of cellGO:00516742440.034
cell surface receptor signaling pathwayGO:00071663250.034
response to biotic stimulusGO:0009607970.033
biosynthetic processGO:00090582940.033
agingGO:000756820.033
nuclear importGO:005117030.033
cell cycleGO:0007049930.033
regulation of reproductive processGO:200024140.032
anterior posterior pattern specificationGO:00099521520.032
hematopoietic or lymphoid organ developmentGO:00485341910.032
cellular macromolecule biosynthetic processGO:00346452240.032
apoptotic processGO:00069151160.032
positive regulation of cell communicationGO:0010647560.032
negative regulation of intracellular transportGO:003238730.031
regulation of dna templated transcription elongationGO:003278430.031
rna transportGO:005065820.031
larval developmentGO:000216420.031
regulation of protein localization to nucleusGO:190018020.031
rna metabolic processGO:00160702190.030
gastrulation with mouth forming secondGO:0001702440.030
internal peptidyl lysine acetylationGO:001839320.030
determination of heart left right asymmetryGO:00613711170.030
regulation of response to biotic stimulusGO:000283120.030
morphogenesis of an epitheliumGO:00020093330.030
response to radiationGO:0009314510.030
female meiotic divisionGO:000714320.030
positive regulation of secretion by cellGO:190353210.030
positive regulation of catabolic processGO:000989640.030
response to other organismGO:0051707970.030
negative regulation of signal transductionGO:0009968940.030
specification of organ identityGO:001009220.030
cell divisionGO:0051301200.029
spindle assembly involved in meiosisGO:009030610.029
multi organism reproductive processGO:0044703360.029
macromolecular complex assemblyGO:0065003350.029
determination of left right symmetryGO:00073681790.029
regulation of cellular biosynthetic processGO:00313262450.028
regulation of oligodendrocyte differentiationGO:004871310.028
regulation of transcription dna templatedGO:00063552130.028
convergent extensionGO:00600261180.028
positive regulation of cell divisionGO:005178120.028
internal protein amino acid acetylationGO:000647520.028
programmed cell deathGO:00125011190.028
germ line stem cell maintenanceGO:003071820.027
regulation of cell differentiationGO:00455951420.027
defense responseGO:0006952470.027
protein acylationGO:004354330.027
embryonic skeletal joint developmentGO:007249830.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
purine nucleoside monophosphate catabolic processGO:000912840.026
dicarboxylic acid transportGO:000683510.026
calcium ion importGO:007050940.026
nucleic acid transportGO:005065720.026
meiotic spindle organizationGO:000021210.026
erk1 and erk2 cascadeGO:007037140.026
neuron differentiationGO:00301823530.025
protein localization to nucleusGO:003450430.025
positive regulation of exocytosisGO:004592110.025
tissue remodelingGO:004877140.025
rna modificationGO:000945120.025
ncrna metabolic processGO:0034660120.025
response to external stimulusGO:00096052640.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
protein localizationGO:0008104400.025
regulation of cytokine productionGO:000181730.025
regulation of protein ubiquitinationGO:003139630.024
regulation of glial cell differentiationGO:004568540.024
dna templated transcription elongationGO:000635430.024
regulation of developmental processGO:00507932470.024
ion transportGO:00068111140.024
atp catabolic processGO:000620040.024
regulation of jak stat cascadeGO:004642530.024
ubiquitin dependent protein catabolic processGO:000651130.023
regulation of receptor activityGO:001046920.023
stem cell differentiationGO:00488631170.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
regulation of nucleoside metabolic processGO:000911820.023
negative regulation of protein transportGO:005122430.023
cytoskeleton organizationGO:0007010960.023
negative regulation of intracellular protein transportGO:009031730.023
proximal distal pattern formationGO:000995410.023
cellular macromolecule localizationGO:0070727210.023
regulation of production of molecular mediator of immune responseGO:000270010.023
positive regulation of cellular processGO:00485222010.022
regulation of protein import into nucleusGO:004230620.022
transcription elongation from rna polymerase ii promoterGO:000636830.022
gtp catabolic processGO:000618420.022
negative regulation of protein phosphorylationGO:000193340.022
gastrulationGO:00073692080.022
regulation of response to stimulusGO:00485832690.022
embryonic skeletal system morphogenesisGO:0048704930.022
regulation of multicellular organismal developmentGO:20000262230.022
peptidyl serine modificationGO:001820920.022
chromosome organizationGO:0051276310.022
single organism transportGO:00447652060.022
hatchingGO:003518840.022
pyruvate metabolic processGO:000609010.022
regulation of nucleotide catabolic processGO:003081120.021
response to chemicalGO:00422213200.021
regulation of meiotic cell cycleGO:005144510.021
multicellular organismal reproductive processGO:0048609350.021
ribosome assemblyGO:004225510.021
positive regulation of glial cell differentiationGO:004568710.021
embryonic skeletal system developmentGO:0048706970.021
cell cycle g1 s phase transitionGO:004484310.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
cellular amino acid metabolic processGO:000652070.021
entrainment of circadian clockGO:000964920.020
spermatid differentiationGO:004851520.020
regulation of metabolic processGO:00192223590.020
negative regulation of nuclear divisionGO:005178430.020
peptidyl serine phosphorylationGO:001810510.020
generation of neuronsGO:00486993850.020
ribosomal small subunit biogenesisGO:004227420.020
positive regulation of notch signaling pathwayGO:004574730.020
negative regulation of protein kinase activityGO:000646940.020
embryonic organ morphogenesisGO:00485622740.020
positive regulation of secretionGO:005104710.020
cellular transition metal ion homeostasisGO:004691630.020
negative regulation of mapk cascadeGO:004340940.020
macromolecule localizationGO:0033036540.020
cell matrix adhesionGO:000716040.020
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.020
regulation of dna recombinationGO:000001820.020
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.020
deathGO:00162651210.020
pancreas developmentGO:0031016840.020
spliceosomal snrnp assemblyGO:000038720.020
primitive hemopoiesisGO:0060215270.020
positive regulation of muscle cell differentiationGO:005114910.020
negative regulation of defense responseGO:003134820.020
mitochondrion organizationGO:000700540.020
ribonucleoprotein complex assemblyGO:002261850.020
exocytosisGO:000688710.019
nucleic acid metabolic processGO:00903042440.019
foregut morphogenesisGO:000744040.019
negative regulation of cellular catabolic processGO:003133030.019
determination of ventral identityGO:0048264210.019
symbiosis encompassing mutualism through parasitismGO:004440340.019
response to unfolded proteinGO:000698620.019
protein targeting to nucleusGO:004474430.019
vasculature developmentGO:00019442780.019
transportGO:00068102200.018
membrane invaginationGO:001032410.018
cellular response to starvationGO:000926710.018
development of primary female sexual characteristicsGO:004654540.018
intracellular receptor signaling pathwayGO:0030522300.018
camera type eye morphogenesisGO:00485931080.018
regulation of purine nucleotide catabolic processGO:003312120.018
adult behaviorGO:003053420.018
negative regulation of catabolic processGO:000989530.018
cellular response to external stimulusGO:007149620.018
regulation of cell divisionGO:0051302120.017
negative regulation of wnt signaling pathwayGO:0030178300.017
extrinsic apoptotic signaling pathwayGO:009719130.017
positive regulation of apoptotic signaling pathwayGO:200123510.017
positive regulation of response to stimulusGO:0048584800.017
positive regulation of transcription dna templatedGO:0045893570.017
myeloid cell differentiationGO:0030099860.017
positive regulation of cell cycleGO:004578730.017
regulation of apoptotic processGO:0042981980.017
sister chromatid cohesionGO:000706220.017
proteasomal protein catabolic processGO:001049820.017
nucleobase containing compound metabolic processGO:00061392740.017
positive regulation of myeloid cell differentiationGO:004563920.017
female sex differentiationGO:004666040.017
stem cell developmentGO:0048864820.017
golgi vesicle transportGO:004819330.017
regulation of cellular metabolic processGO:00313233200.017
embryonic skeletal joint morphogenesisGO:006027230.017
synaptic growth at neuromuscular junctionGO:005112420.017
regulation of epithelial to mesenchymal transitionGO:001071730.017
cell deathGO:00082191210.017
regulation of exocytosisGO:001715710.017
response to topologically incorrect proteinGO:003596620.017
g1 s transition of mitotic cell cycleGO:000008210.017
amino acid transportGO:000686520.017
neurotransmitter secretionGO:000726920.017
cellular biosynthetic processGO:00442492860.016
amide biosynthetic processGO:004360410.016
endocrine hormone secretionGO:006098620.016
b cell activationGO:004211320.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
chromosome organization involved in meiosisGO:007019210.016
neuron projection guidanceGO:0097485860.016
regulation of erk1 and erk2 cascadeGO:007037240.016
regulation of histone methylationGO:003106030.016
neurotransmitter transportGO:000683620.016
negative regulation of kinase activityGO:003367340.016
ovulation cycle processGO:002260220.016
response to endogenous stimulusGO:0009719830.016
response to alkaloidGO:004327920.016
regulation of mrna splicing via spliceosomeGO:004802430.016
renal tubule morphogenesisGO:006133310.016
establishment of localizationGO:00512342440.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
regulation of cellular component organizationGO:0051128860.016
negative regulation of i kappab kinase nf kappab signalingGO:004312410.016
establishment of rna localizationGO:005123630.016
regulation of steroid hormone secretionGO:200083110.016
secondary metabolic processGO:001974830.016
regulation of gtp catabolic processGO:003312420.016
nucleobase containing compound transportGO:001593120.016
organic cyclic compound biosynthetic processGO:19013622230.016
behaviorGO:0007610740.016
negative regulation of myeloid cell differentiationGO:004563810.016
tissue regenerationGO:0042246740.016
central nervous system neuron differentiationGO:0021953740.016
somitogenesisGO:0001756870.015
cytoskeleton dependent cytokinesisGO:006164030.015
microtubule polymerizationGO:004678520.015
synaptic vesicle endocytosisGO:004848810.015
hormone transportGO:000991420.015
determination of dorsal ventral asymmetryGO:0048262340.015
negative regulation of multicellular organismal processGO:0051241690.015
intracellular mrna localizationGO:000829810.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
establishment of endothelial barrierGO:006102830.015
cytoplasm organizationGO:000702840.015
wound healingGO:0042060900.015
antimicrobial humoral responseGO:001973020.015
neuroblast proliferationGO:000740520.015
ribonucleoprotein complex biogenesisGO:0022613130.015
hepaticobiliary system developmentGO:0061008980.015
response to stressGO:00069502630.015
rna localizationGO:000640340.015
cell cycle processGO:0022402530.015
regulation of cell deathGO:00109411030.014
cellular response to organic substanceGO:00713101050.014
production of molecular mediator of immune responseGO:000244020.014
negative regulation of mitosisGO:004583930.014
positive regulation of neural precursor cell proliferationGO:200017910.014
protein trimerizationGO:007020640.014
amine metabolic processGO:000930820.014
cell substrate adhesionGO:003158940.014
phagocytosisGO:000690930.014
regulation of protein complex assemblyGO:004325430.014
embryonic viscerocranium morphogenesisGO:0048703520.014
neuronal stem cell maintenanceGO:009715020.014
mrna transportGO:005102820.014
embryonic hemopoiesisGO:0035162530.014
response to uvGO:000941130.014
l amino acid transportGO:001580710.014
response to abiotic stimulusGO:00096281220.014
negative regulation of developmental processGO:0051093650.014
multi organism processGO:00517041340.014
regulation of cellular protein catabolic processGO:190336210.014
cellular protein modification processGO:00064641000.014
regulation of dendrite morphogenesisGO:004881430.014
digestive tract morphogenesisGO:00485462310.014
gtp metabolic processGO:004603940.014
innate immune responseGO:0045087130.014
regulation of rna biosynthetic processGO:20011412130.014
regulation of rna metabolic processGO:00512522240.014
regulation of wnt signaling pathwayGO:0030111530.014
protein polymerizationGO:005125840.014
regulation of gene silencingGO:006096810.013
regulation of intracellular signal transductionGO:1902531570.013
mononuclear cell proliferationGO:003294310.013
response to light stimulusGO:0009416460.013
regulation of transporter activityGO:003240920.013
central nervous system developmentGO:00074173870.013
dna modificationGO:000630480.013
membrane fusionGO:006102520.013
cell projection organizationGO:00300302840.013
dna methylationGO:000630680.013
g2 dna damage checkpointGO:003157230.013
negative regulation of protein localization to nucleusGO:190018120.013
peptidyl threonine modificationGO:001821010.013
iron ion homeostasisGO:005507240.013
regulation of protein catabolic processGO:004217610.013
mitotic sister chromatid segregationGO:000007060.013
centrosome organizationGO:005129710.013
regulation of gene expression epigeneticGO:0040029110.013
regulation of mesenchymal cell proliferationGO:001046410.013
carboxylic acid metabolic processGO:0019752220.013
centrosome cycleGO:000709810.013
regulation of metal ion transportGO:001095940.013
cellular response to unfolded proteinGO:003462020.013
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
female gonad developmentGO:000858540.013
monocyte differentiationGO:003022420.013
negative regulation of response to stimulusGO:00485851040.013
connective tissue developmentGO:0061448990.013
vesicle localizationGO:0051648270.013
forebrain regionalizationGO:002187140.013
nephron tubule morphogenesisGO:007207810.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
nuclear exportGO:005116810.012
aromatic compound biosynthetic processGO:00194382170.012
response to growth factorGO:0070848390.012
positive regulation of immune effector processGO:000269930.012
regulation of protein bindingGO:004339330.012
cell part morphogenesisGO:00329902460.012
oligodendrocyte differentiationGO:0048709230.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
negative regulation of chromosome organizationGO:200125110.012
establishment of synaptic vesicle localizationGO:009748010.012
covalent chromatin modificationGO:0016569200.012
positive regulation of chromatin modificationGO:190331010.012
spindle assembly involved in female meiosisGO:000705610.012
calcium ion dependent exocytosisGO:001715610.012
response to hexoseGO:000974630.012
alternative mrna splicing via spliceosomeGO:000038010.012
histone h3 k4 methylationGO:005156820.012
negative regulation of translational initiationGO:004594710.012
protein complex subunit organizationGO:0071822460.012
regulation of cell activationGO:005086510.012
regulation of lipid transportGO:003236840.012
modification dependent protein catabolic processGO:001994130.012
positive regulation of lymphocyte mediated immunityGO:000270810.012
regulation of cell proliferation involved in heart morphogenesisGO:200013620.012
optic placode formationGO:000174340.012
cellular protein catabolic processGO:004425740.012
glucose homeostasisGO:004259310.012
response to carbohydrateGO:000974330.012
convergent extension involved in axis elongationGO:0060028260.012
phagocytosis engulfmentGO:000691110.012
cellular response to topologically incorrect proteinGO:003596720.012
leukocyte proliferationGO:007066110.012
negative regulation of rna splicingGO:003311910.012
peptide metabolic processGO:000651810.012
regulation of endocrine processGO:004406020.012
negative regulation of cell communicationGO:0010648960.012
positive regulation of gene expressionGO:0010628710.012
nucleobase containing compound biosynthetic processGO:00346542050.011
regulation of oxidative stress induced cell deathGO:190320120.011
nephron epithelium morphogenesisGO:007208810.011
formation of primary germ layerGO:0001704620.011
system processGO:00030081850.011
regulation of macromolecule metabolic processGO:00602553170.011
guanosine containing compound catabolic processGO:190106920.011
positive regulation of stem cell proliferationGO:200064810.011
endoplasmic reticulum unfolded protein responseGO:003096820.011
positive regulation of dna templated transcription elongationGO:003278610.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
spliceosomal complex assemblyGO:000024510.011
peptidyl tyrosine dephosphorylationGO:003533510.011
response to external biotic stimulusGO:0043207970.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
microtubule cytoskeleton organizationGO:0000226330.011
response to organic substanceGO:00100331530.011
er to golgi vesicle mediated transportGO:000688810.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
wnt signaling pathwayGO:0016055800.011
adherens junction organizationGO:003433240.011
positive regulation of map kinase activityGO:004340630.011
rna biosynthetic processGO:00327741810.011
cell type specific apoptotic processGO:0097285220.011
axon guidanceGO:0007411860.011
growthGO:00400071740.011
positive regulation of cell activationGO:005086710.011
hard palate developmentGO:006002240.011
post embryonic organ developmentGO:004856940.011
cell substrate junction assemblyGO:000704420.011
neuron developmentGO:00486662620.011
desmosome assemblyGO:000215920.011
response to monosaccharideGO:003428430.011
branching morphogenesis of an epithelial tubeGO:0048754150.011
carbohydrate homeostasisGO:003350010.011
cell projection morphogenesisGO:00488582440.011
ovulation cycleGO:004269820.011
response to metal ionGO:0010038340.011
regulation of hormone levelsGO:0010817210.011
organic substance transportGO:0071702580.011

polr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.019
cancerDOID:16200.019
organ system cancerDOID:005068600.019
disease of cellular proliferationDOID:1456600.019
disease of anatomical entityDOID:700.018
muscular diseaseDOID:008000000.016
musculoskeletal system diseaseDOID:1700.016
muscle tissue diseaseDOID:6600.016
intestinal cancerDOID:1015500.012
gastrointestinal system cancerDOID:311900.012
large intestine cancerDOID:567200.012
colorectal cancerDOID:925600.012