Danio rerio

0 known processes

polr2b

polymerase (RNA) II (DNA directed) polypeptide B

(Aliases: zgc:109952)

polr2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.591
Worm
agingGO:000756820.511
ribonucleoside monophosphate catabolic processGO:000915840.302
purine nucleoside monophosphate catabolic processGO:000912840.281
nucleoside monophosphate catabolic processGO:000912540.257
regulation of protein catabolic processGO:004217610.223
nitrogen compound metabolic processGO:00068073190.206
Human
purine ribonucleoside monophosphate catabolic processGO:000916940.202
embryo development ending in birth or egg hatchingGO:00097922710.182
Worm
negative regulation of biological processGO:00485193040.178
single organism localizationGO:19025782250.172
nucleocytoplasmic transportGO:000691340.151
protein localization to nucleusGO:003450430.150
proteasomal protein catabolic processGO:001049820.144
negative regulation of mitosisGO:004583930.140
single organism organelle organizationGO:19025891990.137
membrane fusionGO:006102520.135
gene expressionGO:00104672520.127
Human
atp catabolic processGO:000620040.124
homeostatic processGO:00425921420.123
positive regulation of transportGO:005105020.121
organic cyclic compound metabolic processGO:19013603010.117
Human
negative regulation of chromosome organizationGO:200125110.116
mitotic nuclear divisionGO:0007067180.116
negative regulation of nuclear divisionGO:005178430.114
positive regulation of translationGO:004572710.112
reproductionGO:0000003400.107
Worm
nucleobase containing compound metabolic processGO:00061392740.107
Human
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.105
regulation of cytoplasmic transportGO:190364940.105
negative regulation of metabolic processGO:0009892860.102
single organism nuclear importGO:190259330.101
nuclear transportGO:005116940.101
response to stressGO:00069502630.098
regulation of multicellular organismal processGO:00512392770.096
regulation of nucleocytoplasmic transportGO:004682220.095
sensory organ developmentGO:00074233930.094
organelle organizationGO:00069962270.094
negative regulation of catabolic processGO:000989530.093
regulation of protein localization to nucleusGO:190018020.093
rna metabolic processGO:00160702190.092
Human
cellular process involved in reproduction in multicellular organismGO:0022412280.089
heterocycle biosynthetic processGO:00181302150.087
Human
sequestering of calcium ionGO:005120830.087
negative regulation of cellular catabolic processGO:003133030.086
cellular aromatic compound metabolic processGO:00067252950.085
Human
regulation of mrna processingGO:005068430.084
stem cell divisionGO:001714510.084
regulation of cellular protein catabolic processGO:190336210.083
protein importGO:001703830.083
negative regulation of cellular processGO:00485232830.083
regulation of biological qualityGO:00650082630.082
meiotic nuclear divisionGO:000712640.082
developmental process involved in reproductionGO:0003006270.081
Worm
mitotic cell cycleGO:0000278640.081
sister chromatid segregationGO:000081960.080
mitochondrion organizationGO:000700540.079
maintenance of locationGO:005123540.078
single organism metabolic processGO:00447102170.077
establishment of localizationGO:00512342440.076
transportGO:00068102200.076
purine ribonucleotide metabolic processGO:0009150270.075
ubiquitin dependent protein catabolic processGO:000651130.075
immune system developmentGO:00025201910.074
cytokinesisGO:000091030.073
cellular nitrogen compound metabolic processGO:00346412900.073
Human
mitotic sister chromatid segregationGO:000007060.072
modification dependent protein catabolic processGO:001994130.070
oocyte anterior posterior axis specificationGO:000731440.069
single organism transportGO:00447652060.068
cellular macromolecule metabolic processGO:00442603910.067
Human
cell cycle processGO:0022402530.067
regulation of metabolic processGO:00192223590.066
mitotic cell cycle processGO:1903047480.066
regulation of primary metabolic processGO:00800903110.065
multicellular organism growthGO:003526440.065
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.064
phosphorus metabolic processGO:00067931090.064
germ cell developmentGO:0007281220.064
heterocycle metabolic processGO:00464832900.062
Human
nuclear importGO:005117030.062
negative regulation of macromolecule metabolic processGO:0010605760.061
organonitrogen compound metabolic processGO:1901564740.060
regulation of nitrogen compound metabolic processGO:00511712510.060
organelle fissionGO:0048285230.057
chordate embryonic developmentGO:00430092710.055
rna polyadenylationGO:004363120.055
nuclear divisionGO:0000280230.054
positive regulation of biological processGO:00485182530.053
regulation of protein import into nucleusGO:004230620.053
organism emergence from protective structureGO:007168440.052
Worm
cellular protein catabolic processGO:004425740.052
establishment of protein localization to organelleGO:007259440.050
positive regulation of cellular processGO:00485222010.050
organic substance biosynthetic processGO:19015762890.050
Human
negative regulation of synapse assemblyGO:005196420.049
small molecule metabolic processGO:0044281770.049
regulation of synaptic growth at neuromuscular junctionGO:000858210.049
negative regulation of mrna metabolic processGO:190331230.049
cell cycleGO:0007049930.049
microtubule cytoskeleton organization involved in mitosisGO:190285010.048
dna templated transcription initiationGO:000635210.048
locomotor rhythmGO:004547530.048
positive regulation of catabolic processGO:000989640.047
camera type eye developmentGO:00430102220.047
organic cyclic compound biosynthetic processGO:19013622230.046
Human
cellular localizationGO:0051641970.046
protein import into nucleusGO:000660630.045
rna biosynthetic processGO:00327741810.045
Human
actin filament based processGO:0030029640.045
regulation of protein transportGO:005122330.044
nucleic acid metabolic processGO:00903042440.044
Human
single organism reproductive processGO:0044702400.043
Worm
hormone transportGO:000991420.043
phosphate containing compound metabolic processGO:00067961080.043
deathGO:00162651210.042
regulation of signal transductionGO:00099662250.042
erk1 and erk2 cascadeGO:007037140.041
regulation of localizationGO:00328791040.041
cellular response to nutrient levelsGO:003166920.040
hemopoiesisGO:00300971830.040
regulation of signalingGO:00230512350.039
nucleobase containing compound biosynthetic processGO:00346542050.039
Human
gtp catabolic processGO:000618420.039
fertilizationGO:000956630.039
dna templated transcription elongationGO:000635430.039
rhythmic behaviorGO:000762250.038
regulation of protein complex assemblyGO:004325430.038
eye developmentGO:00016542770.038
maternal determination of anterior posterior axis embryoGO:000835840.038
lateral inhibitionGO:004633110.037
locomotory behaviorGO:0007626340.037
protein stabilizationGO:005082120.037
amine metabolic processGO:000930820.036
regulation of developmental processGO:00507932470.036
signal transductionGO:00071654550.036
cellular component assemblyGO:00226071700.035
carbohydrate derivative metabolic processGO:1901135610.035
pole plasm assemblyGO:000731540.034
positive regulation of cytosolic calcium ion concentrationGO:000720440.034
regulation of reproductive processGO:200024140.034
mitotic metaphase plate congressionGO:000708010.034
rna localizationGO:000640340.033
peptide transportGO:001583310.033
regulation of erk1 and erk2 cascadeGO:007037240.033
modification dependent macromolecule catabolic processGO:004363230.033
transcription dna templatedGO:00063511810.033
Human
blood vessel morphogenesisGO:00485142160.033
regulation of multicellular organismal developmentGO:20000262230.033
negative regulation of ras protein signal transductionGO:004658010.032
ion homeostasisGO:0050801410.032
autophagyGO:000691440.031
positive regulation of erk1 and erk2 cascadeGO:007037420.031
compound eye developmentGO:004874920.031
chemical homeostasisGO:0048878490.031
response to carbohydrateGO:000974330.030
cytoskeleton organizationGO:0007010960.030
regulation of establishment of protein localizationGO:007020140.030
positive regulation of apoptotic signaling pathwayGO:200123510.030
developmental growthGO:00485891660.030
organophosphate metabolic processGO:0019637370.029
nucleic acid templated transcriptionGO:00976591810.029
Human
regulation of protein targetingGO:190353320.029
cell deathGO:00082191210.029
positive regulation of cellular catabolic processGO:003133130.028
embryonic organ developmentGO:00485683810.028
enzyme linked receptor protein signaling pathwayGO:00071671060.028
stem cell proliferationGO:007208940.028
cellular nitrogen compound biosynthetic processGO:00442712180.028
Human
proteolysis involved in cellular protein catabolic processGO:005160330.028
locomotionGO:00400113130.027
Worm
retina development in camera type eyeGO:00600411460.027
spliceosomal complex assemblyGO:000024510.027
embryonic organ morphogenesisGO:00485622740.027
cytosolic calcium ion transportGO:006040130.027
apoptotic processGO:00069151160.027
regulation of synapse organizationGO:005080730.027
regulation of response to stimulusGO:00485832690.027
pancreas developmentGO:0031016840.026
cellular component biogenesisGO:00440851780.026
immune system processGO:00023762410.026
ribonucleotide metabolic processGO:0009259270.026
negative regulation of cell cycle phase transitionGO:190198850.026
cell fate commitmentGO:0045165990.026
stem cell developmentGO:0048864820.026
cellular amine metabolic processGO:004410620.025
vasculature developmentGO:00019442780.025
negative regulation of gene expressionGO:0010629650.024
regulation of macromolecule metabolic processGO:00602553170.024
adult behaviorGO:003053420.024
multi organism processGO:00517041340.024
response to monosaccharideGO:003428430.024
organic substance catabolic processGO:1901575280.023
release of sequestered calcium ion into cytosolGO:005120930.023
cell surface receptor signaling pathwayGO:00071663250.023
protein metabolic processGO:00195381830.022
negative regulation of protein phosphorylationGO:000193340.022
regulation of programmed cell deathGO:00430671010.022
regulation of intracellular protein transportGO:003315730.022
regulation of epithelial cell proliferationGO:005067830.022
biosynthetic processGO:00090582940.021
Human
response to ketoneGO:190165410.021
mrna polyadenylationGO:000637820.021
negative regulation of developmental processGO:0051093650.021
positive regulation of cellular metabolic processGO:0031325940.021
rhythmic processGO:0048511210.021
microtubule based processGO:0007017600.020
cellular protein metabolic processGO:00442671290.020
negative regulation of multicellular organismal processGO:0051241690.020
purine nucleotide metabolic processGO:0006163270.020
glucose homeostasisGO:004259310.020
negative regulation of protein kinase activityGO:000646940.020
ribose phosphate metabolic processGO:0019693270.020
regulation of molecular functionGO:0065009700.020
regulation of cell communicationGO:00106462320.019
response to hexoseGO:000974630.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
programmed cell deathGO:00125011190.019
regulation of alternative mrna splicing via spliceosomeGO:000038110.019
actin cytoskeleton organizationGO:0030036630.019
negative regulation of biosynthetic processGO:0009890550.019
rna 3 end processingGO:003112320.019
cellular response to organic substanceGO:00713101050.019
er to golgi vesicle mediated transportGO:000688810.019
cellular response to external stimulusGO:007149620.019
negative regulation of small gtpase mediated signal transductionGO:005105810.019
regulation of extrinsic apoptotic signaling pathwayGO:200123630.019
ncrna catabolic processGO:003466110.019
tube morphogenesisGO:00352393490.019
regulation of gene expressionGO:00104682650.019
single organism membrane fusionGO:004480120.019
gamete generationGO:0007276330.019
regulation of protein maturationGO:1903317100.019
protein targeting to nucleusGO:004474430.019
carbohydrate homeostasisGO:003350010.018
neuroblast proliferationGO:000740520.018
transcription from rna polymerase ii promoterGO:0006366800.018
Human
regionalizationGO:00030022740.018
viral processGO:001603210.018
negative regulation of sequestering of calcium ionGO:005128340.018
metal ion homeostasisGO:0055065260.018
negative regulation of cytoplasmic transportGO:190365020.018
regulation of cellular amino acid metabolic processGO:000652100.018
cytoplasm organizationGO:000702840.018
cytoskeleton dependent cytokinesisGO:006164030.018
regulation of catalytic activityGO:0050790550.018
purine ribonucleoside metabolic processGO:0046128100.018
cellular response to extracellular stimulusGO:003166820.018
growthGO:00400071740.018
phototransductionGO:000760220.018
regulation of rna metabolic processGO:00512522240.017
calcium ion transport into cytosolGO:006040230.017
positive regulation of mrna metabolic processGO:190331320.017
synaptic growth at neuromuscular junctionGO:005112420.017
response to woundingGO:00096111160.017
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.017
regulation of protein metabolic processGO:0051246560.017
cellular macromolecular complex assemblyGO:0034622240.017
mrna 3 end processingGO:003112420.017
small gtpase mediated signal transductionGO:000726480.017
posttranscriptional regulation of gene expressionGO:0010608140.017
regulation of cellular ketone metabolic processGO:001056570.017
negative regulation of protein maturationGO:1903318100.017
single fertilizationGO:000733830.017
response to chemicalGO:00422213200.017
muscle cell developmentGO:00550011150.017
golgi vesicle transportGO:004819330.017
macromolecule biosynthetic processGO:00090592270.017
Human
double strand break repairGO:000630230.017
regulation of apoptotic processGO:0042981980.017
neuron differentiationGO:00301823530.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
regulation of synapse assemblyGO:005196330.017
regulation of cellular amine metabolic processGO:003323800.017
guanosine containing compound catabolic processGO:190106920.017
nucleic acid transportGO:005065720.017
primary neural tube formationGO:001402010.017
dendrite guidanceGO:007098300.017
nucleotide metabolic processGO:0009117280.017
interspecies interaction between organismsGO:004441940.017
cell morphogenesisGO:00009022890.017
macromolecular complex assemblyGO:0065003350.016
microtubule cytoskeleton organizationGO:0000226330.016
aromatic compound biosynthetic processGO:00194382170.016
Human
pigmentationGO:0043473850.016
membrane invaginationGO:001032410.016
anterior posterior pattern specificationGO:00099521520.016
transmembrane transportGO:00550851200.016
striated muscle cell differentiationGO:00511461290.016
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.016
purine ribonucleoside monophosphate metabolic processGO:000916750.016
protein polymerizationGO:005125840.016
protein localization to plasma membraneGO:007265910.016
cell divisionGO:0051301200.016
generation of neuronsGO:00486993850.016
regulation of sequestering of calcium ionGO:005128240.016
zymogen activationGO:003163830.016
positive regulation of chromatin modificationGO:190331010.016
establishment of localization in cellGO:0051649770.016
sequestering of metal ionGO:005123830.016
negative regulation of defense responseGO:003134820.016
gtp metabolic processGO:004603940.016
guanosine containing compound metabolic processGO:190106840.016
regulation of cellular metabolic processGO:00313233200.016
alternative mrna splicing via spliceosomeGO:000038010.016
rna stabilizationGO:004348940.015
negative regulation of cellular metabolic processGO:0031324770.015
positive regulation of apoptotic processGO:0043065290.015
cellular amino acid metabolic processGO:000652070.015
positive regulation of signal transductionGO:0009967560.015
negative regulation of dna metabolic processGO:005105340.015
cellular ion homeostasisGO:0006873170.015
regulation of cell shapeGO:000836010.015
cellular component maintenanceGO:004395430.015
cation transportGO:0006812810.015
cell proliferationGO:0008283800.015
negative regulation of kinase activityGO:003367340.015
regulation of proteolysisGO:0030162240.015
hormone secretionGO:004687920.015
regulation of calcium ion transportGO:005192420.015
negative regulation of proteolysisGO:0045861100.014
regulation of circadian rhythmGO:004275240.014
pigment granule localizationGO:0051875250.014
protein complex subunit organizationGO:0071822460.014
regulation of cytokine productionGO:000181730.014
cell projection morphogenesisGO:00488582440.014
intracellular mrna localizationGO:000829810.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
negative regulation of signalingGO:0023057960.014
cellular chemical homeostasisGO:0055082170.014
cellular cation homeostasisGO:0030003170.014
extrinsic apoptotic signaling pathwayGO:009719130.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
behaviorGO:0007610740.014
chromosome localizationGO:005000020.014
regulation of cellular component organizationGO:0051128860.014
divalent inorganic cation homeostasisGO:0072507220.013
multi organism cellular processGO:004476420.013
positive regulation of ras protein signal transductionGO:004657910.013
protein processingGO:0016485120.013
multicellular organismal reproductive processGO:0048609350.013
cellular homeostasisGO:0019725260.013
activation of mapkkk activityGO:000018510.013
negative regulation of mrna processingGO:005068610.013
circadian rhythmGO:0007623190.013
protein complex assemblyGO:0006461300.013
system processGO:00030081850.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
positive regulation of mrna processingGO:005068510.013
multicellular organismal metabolic processGO:004423620.013
negative regulation of rna splicingGO:003311910.013
single organism intracellular transportGO:1902582250.013
regulation of rna biosynthetic processGO:20011412130.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
mrna processingGO:0006397140.012
regulation of chromosome segregationGO:005198310.012
cellular transition metal ion homeostasisGO:004691630.012
positive regulation of chromosome organizationGO:200125210.012
blood vessel developmentGO:00015682460.012
metal ion transportGO:0030001580.012
centrosome organizationGO:005129710.012
cellular response to chemical stimulusGO:00708871570.012
carboxylic acid metabolic processGO:0019752220.012
cell cell signalingGO:0007267520.012
regulation of multicellular organism growthGO:004001440.012
negative regulation of apoptotic processGO:0043066550.012
single organism cellular localizationGO:1902580460.012
nuclear exportGO:005116810.012
oxoacid metabolic processGO:0043436310.012
muscle cell differentiationGO:00426921390.012
ion transportGO:00068111140.012
macromolecule localizationGO:0033036540.012
regulation of cell activationGO:005086510.011
cellular biosynthetic processGO:00442492860.011
Human
cell projection organizationGO:00300302840.011
muscle organ developmentGO:00075171010.011
protein maturationGO:0051604120.011
sexual reproductionGO:0019953360.011
multi organism reproductive processGO:0044703360.011
regulation of cellular biosynthetic processGO:00313262450.011
meiotic cell cycle processGO:190304630.011
monocyte differentiationGO:003022420.011
regulation of transportGO:0051049450.011
mechanosensory behaviorGO:000763820.011
mrna stabilizationGO:004825540.011
segmentationGO:0035282970.011
regulation of growth rateGO:004000910.011
regulation of nucleoside metabolic processGO:000911820.011
regulation of meiotic cell cycleGO:005144510.011
striated muscle cell developmentGO:00550021080.011
purine ribonucleoside triphosphate metabolic processGO:000920590.011
cellular component movementGO:00069283350.011
Worm
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.011
nucleobase containing compound transportGO:001593120.011
positive regulation of cell activationGO:005086710.011
developmental programmed cell deathGO:001062340.011
single organism behaviorGO:0044708240.011
lymphocyte proliferationGO:004665110.011
regulation of stem cell proliferationGO:007209120.011
negative regulation of protein import into nucleusGO:004230820.011
regulation of peptidase activityGO:0052547230.011
cellular ketone metabolic processGO:0042180110.011
organelle assemblyGO:00709251100.011
cellular protein complex assemblyGO:0043623190.011
response to organic substanceGO:00100331530.011
establishment of rna localizationGO:005123630.011
regulation of endopeptidase activityGO:0052548230.011
regulation of biosynthetic processGO:00098892500.011
response to topologically incorrect proteinGO:003596620.011
multicellular organism reproductionGO:0032504350.011
regulation of protein ubiquitinationGO:003139630.011
regulation of mitotic cell cycleGO:0007346250.010
macromolecular complex disassemblyGO:003298410.010
macromolecular complex subunit organizationGO:0043933740.010
regulation of epidermis developmentGO:004568220.010
melanosome localizationGO:0032400210.010
internal peptidyl lysine acetylationGO:001839320.010
protein n linked glycosylationGO:000648710.010
reproductive processGO:0022414400.010
Worm
nucleoside metabolic processGO:0009116110.010
female gamete generationGO:0007292140.010
regulation of transcription dna templatedGO:00063552130.010
protein homooligomerizationGO:005126030.010
rna export from nucleusGO:000640510.010
regulation of protein processingGO:0070613100.010
negative regulation of protein metabolic processGO:0051248160.010
spermatid differentiationGO:004851520.010
oocyte constructionGO:000730850.010
rna splicingGO:0008380160.010
protein complex disassemblyGO:004324110.010

polr2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.018
motor neuron diseaseDOID:23100.018
amyotrophic lateral sclerosisDOID:33200.018
neurodegenerative diseaseDOID:128900.018
central nervous system diseaseDOID:33100.018
sensory system diseaseDOID:005015500.016
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.016
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.013
cancerDOID:16200.013