Danio rerio

0 known processes

spns1

spinster homolog 1 (Drosophila)

(Aliases: spinl,wu:fi37e11,MGC55239,nrs,etID64740.3,wu:fb95b12)

spns1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell surface receptor signaling pathwayGO:00071663250.154
Zebrafish Fly
larval developmentGO:000216420.110
Worm
autophagyGO:000691440.092
establishment of localizationGO:00512342440.086
Fly
establishment of protein localization to organelleGO:007259440.081
regulation of cell communicationGO:00106462320.075
Fly
meiotic nuclear divisionGO:000712640.074
regulation of response to stimulusGO:00485832690.072
Fly
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.065
axon developmentGO:00615641660.061
cellular protein catabolic processGO:004425740.060
cell part morphogenesisGO:00329902460.057
agingGO:000756820.056
cell projection morphogenesisGO:00488582440.053
signal transductionGO:00071654550.051
Zebrafish Fly
regulation of metabolic processGO:00192223590.050
modification dependent protein catabolic processGO:001994130.050
positive regulation of cellular catabolic processGO:003133130.049
immune system processGO:00023762410.047
adult behaviorGO:003053420.047
regulation of signal transductionGO:00099662250.046
Fly
cellular response to nutrient levelsGO:003166920.046
Fly
positive regulation of catabolic processGO:000989640.044
transportGO:00068102200.044
Fly
regulation of autophagyGO:001050630.044
cell morphogenesis involved in differentiationGO:00009041950.043
axonogenesisGO:00074091520.043
macroautophagyGO:001623610.040
lipid storageGO:001991510.040
response to stressGO:00069502630.040
Fly
cell projection organizationGO:00300302840.039
ubiquitin dependent protein catabolic processGO:000651130.037
maintenance of locationGO:005123540.037
modification dependent macromolecule catabolic processGO:004363230.037
tube morphogenesisGO:00352393490.037
Zebrafish
golgi vesicle transportGO:004819330.036
cellular response to extracellular stimulusGO:003166820.036
Fly
cellular response to starvationGO:000926710.036
Fly
regulation of multicellular organism growthGO:004001440.035
meiotic chromosome segregationGO:004513230.035
meiotic cell cycle processGO:190304630.035
tissue remodelingGO:004877140.034
cell morphogenesis involved in neuron differentiationGO:00486671630.033
extrinsic apoptotic signaling pathwayGO:009719130.032
negative regulation of protein phosphorylationGO:000193340.032
regulation of synapse assemblyGO:005196330.031
Fly
gastrulationGO:00073692080.031
hematopoietic or lymphoid organ developmentGO:00485341910.030
embryo development ending in birth or egg hatchingGO:00097922710.030
Zebrafish Worm
multicellular organism growthGO:003526440.030
stem cell proliferationGO:007208940.030
protein stabilizationGO:005082120.030
cellular component morphogenesisGO:00329893360.029
biosynthetic processGO:00090582940.029
digestive tract developmentGO:00485652650.029
cellular biosynthetic processGO:00442492860.028
single organism membrane fusionGO:004480120.028
positive regulation of cellular component biogenesisGO:004408930.028
negative regulation of kinase activityGO:003367340.028
regulation of response to nutrient levelsGO:003210710.028
cell migrationGO:00164772370.027
Zebrafish Worm Fly
single organism metabolic processGO:00447102170.027
alpha amino acid metabolic processGO:190160530.027
negative regulation of protein kinase activityGO:000646940.027
gland developmentGO:00487321430.027
proteasomal protein catabolic processGO:001049820.027
regulation of response to extracellular stimulusGO:003210410.027
neuron developmentGO:00486662620.027
organic substance biosynthetic processGO:19015762890.027
intracellular signal transductionGO:0035556850.027
phosphate containing compound metabolic processGO:00067961080.027
positive regulation of map kinase activityGO:004340630.026
organelle fusionGO:004828430.026
locomotionGO:00400113130.026
Zebrafish Worm Fly
response to external biotic stimulusGO:0043207970.026
response to abiotic stimulusGO:00096281220.026
negative regulation of response to stimulusGO:00485851040.026
Fly
regulation of signalingGO:00230512350.026
Fly
positive regulation of transportGO:005105020.025
compound eye developmentGO:004874920.025
deathGO:00162651210.025
Fly
stem cell divisionGO:001714510.025
guanosine containing compound metabolic processGO:190106840.025
cellular transition metal ion homeostasisGO:004691630.025
neuron differentiationGO:00301823530.025
generation of neuronsGO:00486993850.025
cellular component assemblyGO:00226071700.025
Fly
cellular response to external stimulusGO:007149620.025
Fly
localization of cellGO:00516742440.024
Zebrafish Worm Fly
cellular ketone metabolic processGO:0042180110.024
positive regulation of biological processGO:00485182530.024
neuron projection developmentGO:00311751800.024
digestive tract morphogenesisGO:00485462310.024
mitochondrion organizationGO:000700540.024
cellular amino acid metabolic processGO:000652070.023
phagocytosisGO:000690930.023
neuroblast proliferationGO:000740520.023
regulation of cell projection assemblyGO:006049140.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.023
protein import into nucleusGO:000660630.023
neurotransmitter transportGO:000683620.023
cellular amino acid biosynthetic processGO:000865220.023
immune system developmentGO:00025201910.023
single organism transportGO:00447652060.023
Fly
cellular response to chemical stimulusGO:00708871570.022
response to other organismGO:0051707970.022
regulation of protein catabolic processGO:004217610.022
proteolysis involved in cellular protein catabolic processGO:005160330.022
regulation of bindingGO:005109830.022
gtp catabolic processGO:000618420.022
cell growthGO:0016049570.022
developmental growthGO:00485891660.022
Fly
negative regulation of cellular processGO:00485232830.021
Fly
sensory organ developmentGO:00074233930.021
transmembrane transportGO:00550851200.021
regulation of protein transportGO:005122330.021
rna localizationGO:000640340.021
axon ensheathment in central nervous systemGO:003229120.021
organelle assemblyGO:00709251100.021
regulation of developmental processGO:00507932470.021
Zebrafish Fly
protein homooligomerizationGO:005126030.021
developmental cell growthGO:0048588520.021
regulation of blood vessel sizeGO:005088020.021
negative regulation of signalingGO:0023057960.020
Fly
peptidyl serine modificationGO:001820920.020
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
Fly
positive regulation of cell cycleGO:004578730.020
cellular macromolecule metabolic processGO:00442603910.020
nucleic acid transportGO:005065720.020
cellular component movementGO:00069283350.020
Zebrafish Worm Fly
guanosine containing compound catabolic processGO:190106920.020
regulation of cytokine productionGO:000181730.020
oxoacid metabolic processGO:0043436310.020
protein localization to nucleusGO:003450430.020
cellular response to organic substanceGO:00713101050.020
membrane fusionGO:006102520.020
regulation of meiotic cell cycleGO:005144510.019
regulation of tube sizeGO:003515020.019
nitrogen compound metabolic processGO:00068073190.019
digestive system developmentGO:00551232890.019
regulation of synaptic plasticityGO:004816710.019
negative regulation of epithelial cell proliferationGO:005068010.019
female meiotic divisionGO:000714320.019
camera type eye developmentGO:00430102220.019
positive regulation of apoptotic signaling pathwayGO:200123510.019
regulation of cellular amino acid metabolic processGO:000652100.019
gtp metabolic processGO:004603940.019
carboxylic acid catabolic processGO:004639530.019
negative regulation of signal transductionGO:0009968940.019
Fly
response to hexoseGO:000974630.018
protein metabolic processGO:00195381830.018
actin filament polymerizationGO:003004120.018
urogenital system developmentGO:0001655970.018
regulation of protein targetingGO:190353320.018
response to uvGO:000941130.018
positive regulation of protein complex assemblyGO:003133420.018
regulation of cellular metabolic processGO:00313233200.018
neurotransmitter secretionGO:000726920.018
response to chemicalGO:00422213200.018
cognitionGO:005089010.018
neuron projection morphogenesisGO:00488121610.018
detection of stimulusGO:0051606290.018
cellular carbohydrate metabolic processGO:004426240.018
synaptic target recognitionGO:000803910.018
cellular protein metabolic processGO:00442671290.018
heterocycle metabolic processGO:00464832900.018
brain developmentGO:00074202930.018
synaptic vesicle transportGO:004848910.017
Fly
response to monosaccharideGO:003428430.017
establishment of synaptic vesicle localizationGO:009748010.017
Fly
synaptic growth at neuromuscular junctionGO:005112420.017
Fly
regulation of cytoplasmic transportGO:190364940.017
membrane invaginationGO:001032410.017
negative regulation of cell communicationGO:0010648960.017
Fly
cellular amine metabolic processGO:004410620.017
growthGO:00400071740.017
Fly
regulation of i kappab kinase nf kappab signalingGO:004312240.017
blood vessel developmentGO:00015682460.017
Zebrafish
regulation of protein complex assemblyGO:004325430.017
cell agingGO:000756920.017
regulation of cellular ketone metabolic processGO:001056570.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
Fly
vacuolar transportGO:000703420.017
Fly
cation transmembrane transportGO:0098655650.016
gene expressionGO:00104672520.016
regulation of cellular amine metabolic processGO:003323800.016
apoptotic processGO:00069151160.016
Fly
cell cycle arrestGO:000705010.016
striated muscle tissue developmentGO:00147061100.016
cell matrix adhesionGO:000716040.016
response to corticosteroidGO:003196010.016
regulation of synapse organizationGO:005080730.016
Fly
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
post golgi vesicle mediated transportGO:000689210.016
regulation of skeletal muscle tissue developmentGO:004864140.016
single organism nuclear importGO:190259330.016
protein polymerizationGO:005125840.016
regulation of nucleoside metabolic processGO:000911820.016
activation of mapk activityGO:000018730.016
carboxylic acid metabolic processGO:0019752220.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
nucleobase containing compound metabolic processGO:00061392740.016
erk1 and erk2 cascadeGO:007037140.016
regulation of macromolecule metabolic processGO:00602553170.016
lipid catabolic processGO:001604240.016
protein targeting to nucleusGO:004474430.016
cellular aromatic compound metabolic processGO:00067252950.016
regenerationGO:0031099910.016
organic acid metabolic processGO:0006082310.016
cellular macromolecule biosynthetic processGO:00346452240.016
regionalizationGO:00030022740.016
actin filament based movementGO:003004810.016
catabolic processGO:0009056320.015
regulation of protein bindingGO:004339330.015
regulation of production of molecular mediator of immune responseGO:000270010.015
epithelial cell differentiationGO:00308551160.015
vasculature developmentGO:00019442780.015
Zebrafish
organonitrogen compound metabolic processGO:1901564740.015
regulation of reactive oxygen species metabolic processGO:200037720.015
cell deathGO:00082191210.015
Fly
regulation of intracellular signal transductionGO:1902531570.015
regulation of macromolecule biosynthetic processGO:00105562250.015
nuclear transportGO:005116940.015
protein secretionGO:000930610.015
negative regulation of catabolic processGO:000989530.015
positive regulation of camp biosynthetic processGO:003081920.015
defense response to bacteriumGO:0042742220.015
synaptic vesicle localizationGO:009747910.015
Fly
amine metabolic processGO:000930820.015
regulation of erk1 and erk2 cascadeGO:007037240.015
macromolecule biosynthetic processGO:00090592270.015
cellular component disassemblyGO:002241110.015
iron ion homeostasisGO:005507240.015
regulation of cell activationGO:005086510.015
astrocyte differentiationGO:004870810.014
establishment of blood brain barrierGO:006085620.014
production of molecular mediator of immune responseGO:000244020.014
embryonic limb morphogenesisGO:003032620.014
protein targeting to vacuoleGO:000662310.014
defense response to other organismGO:0098542330.014
defense response to gram negative bacteriumGO:005082980.014
negative regulation of sequestering of calcium ionGO:005128340.014
stem cell maintenanceGO:001982740.014
hepaticobiliary system developmentGO:0061008980.014
neuron projection guidanceGO:0097485860.014
cytoplasm organizationGO:000702840.014
locomotor rhythmGO:004547530.014
protein importGO:001703830.014
negative regulation of defense responseGO:003134820.014
regulation of cell shapeGO:000836010.014
cell substrate adhesionGO:003158940.014
positive regulation of cytoskeleton organizationGO:005149530.014
regulation of neurotransmitter transportGO:005158810.014
mononuclear cell proliferationGO:003294310.014
post embryonic organ developmentGO:004856940.014
signal transduction in absence of ligandGO:003803410.014
synaptic transmission cholinergicGO:000727140.014
angiogenesisGO:00015251580.013
Zebrafish
positive regulation of nucleoside metabolic processGO:004597910.013
cellular respirationGO:004533330.013
multicellular organismal macromolecule metabolic processGO:004425920.013
regulation of establishment of protein localizationGO:007020140.013
small molecule metabolic processGO:0044281770.013
cellular response to reactive oxygen speciesGO:003461420.013
regulation of cellular component sizeGO:0032535300.013
apoptotic process involved in developmentGO:190274220.013
Fly
negative regulation of protein serine threonine kinase activityGO:007190120.013
establishment of protein localization to vacuoleGO:007266610.013
nucleocytoplasmic transportGO:000691340.013
organelle organizationGO:00069962270.013
Fly
positive regulation of secretion by cellGO:190353210.013
hormone secretionGO:004687920.013
regulation of filopodium assemblyGO:005148920.013
establishment of protein localization to plasma membraneGO:009000210.013
muscle cell migrationGO:001481240.013
lymphocyte proliferationGO:004665110.013
regulation of reproductive processGO:200024140.013
Fly
peptidyl serine phosphorylationGO:001810510.013
regulation of carbohydrate metabolic processGO:000610940.013
blood vessel morphogenesisGO:00485142160.013
Zebrafish
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
microtubule cytoskeleton organization involved in mitosisGO:190285010.013
nucleobase containing compound transportGO:001593120.013
i kappab kinase nf kappab signalingGO:000724940.013
regulation of nucleotide catabolic processGO:003081120.013
notch signaling pathwayGO:0007219350.013
cellular component biogenesisGO:00440851780.013
Fly
inorganic cation transmembrane transportGO:0098662500.013
regulation of organelle assemblyGO:190211540.013
hemopoiesisGO:00300971830.013
positive regulation of immune effector processGO:000269930.012
b cell activationGO:004211320.012
dicarboxylic acid transportGO:000683510.012
regulation of cellular component organizationGO:0051128860.012
Fly
eye developmentGO:00016542770.012
regulation of inflammatory responseGO:005072720.012
macromolecule modificationGO:00434121110.012
regulation of gtpase activityGO:004308720.012
positive regulation of secretionGO:005104710.012
aromatic compound biosynthetic processGO:00194382170.012
secondary metabolic processGO:001974830.012
regulation of purine nucleotide catabolic processGO:003312120.012
microtubule organizing center organizationGO:003102310.012
atp catabolic processGO:000620040.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
response to decreased oxygen levelsGO:0036293250.012
nucleic acid templated transcriptionGO:00976591810.012
lysosomal transportGO:000704120.012
Fly
actin polymerization or depolymerizationGO:000815420.012
negative regulation of biological processGO:00485193040.012
Fly
sensory perception of chemical stimulusGO:000760630.012
response to hydrogen peroxideGO:004254230.012
negative regulation of mapk cascadeGO:004340940.012
establishment of rna localizationGO:005123630.012
phosphatidylinositol 3 kinase signalingGO:001406520.012
regulation of multicellular organismal processGO:00512392770.012
Zebrafish Fly
ion transmembrane transportGO:0034220910.012
negative regulation of autophagyGO:001050710.012
positive regulation of protein polymerizationGO:003227320.012
regulation of intracellular protein transportGO:003315730.012
cellular response to molecule of bacterial originGO:007121930.012
embryonic organ morphogenesisGO:00485622740.011
Zebrafish
nuclear importGO:005117030.011
negative regulation of synapse assemblyGO:005196420.011
heart developmentGO:00075073130.011
Zebrafish
hormone biosynthetic processGO:004244630.011
single organism organelle organizationGO:19025891990.011
response to glucoseGO:000974930.011
cellular modified amino acid metabolic processGO:000657530.011
positive regulation of gtpase activityGO:004354710.011
regulation of programmed cell deathGO:00430671010.011
Fly
response to topologically incorrect proteinGO:003596620.011
regulation of neurotransmitter secretionGO:004692810.011
lateral inhibitionGO:004633110.011
regulation of epithelial cell proliferationGO:005067830.011
morphogenesis of an epitheliumGO:00020093330.011
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
odontogenesis of dentin containing toothGO:004247510.011
cell morphogenesisGO:00009022890.011
homeostasis of number of cellsGO:0048872620.011
chemosensory behaviorGO:000763510.011
amino acid transportGO:000686520.011
inositol lipid mediated signalingGO:004801720.011
negative chemotaxisGO:005091910.011
protein acylationGO:004354330.011
chemotaxisGO:00069351040.011
transcription dna templatedGO:00063511810.011
regulation of organ growthGO:004662030.011
glial cell migrationGO:000834730.011
Fly
developmental growth involved in morphogenesisGO:0060560860.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
rna metabolic processGO:00160702190.011
regulation of cellular protein catabolic processGO:190336210.011
regulation of membrane potentialGO:0042391230.011
protein polyubiquitinationGO:000020940.011
response to phGO:000926820.011
pole plasm assemblyGO:000731540.011
negative regulation of chemotaxisGO:005092240.011
embryonic organ developmentGO:00485683810.011
Zebrafish
embryonic skeletal system morphogenesisGO:0048704930.011
Zebrafish
response to light stimulusGO:0009416460.011
single organism biosynthetic processGO:0044711710.011
carbohydrate biosynthetic processGO:001605110.011
single organism localizationGO:19025782250.011
Fly
female sex differentiationGO:004666040.011
inorganic ion transmembrane transportGO:0098660570.011
somatic muscle developmentGO:000752540.011
regulation of primary metabolic processGO:00800903110.011
response to carbohydrateGO:000974330.011
regulation of circadian sleep wake cycleGO:004274910.010
kidney developmentGO:0001822920.010
phosphorylationGO:0016310690.010
negative regulation of multi organism processGO:004390130.010
response to organic substanceGO:00100331530.010
regulation of phGO:000688530.010
ketone biosynthetic processGO:004218120.010
skeletal muscle organ developmentGO:0060538780.010
embryonic skeletal system developmentGO:0048706970.010
Zebrafish
negative regulation of cytokine productionGO:000181810.010
transmission of nerve impulseGO:0019226190.010
cellular response to decreased oxygen levelsGO:003629410.010
g protein coupled receptor signaling pathwayGO:0007186740.010
Zebrafish
convergent extensionGO:00600261180.010
endosomal transportGO:001619720.010
Fly
establishment of epithelial cell polarityGO:009016220.010
regulation of protein import into nucleusGO:004230620.010
programmed cell deathGO:00125011190.010
Fly
regulation of gene expressionGO:00104682650.010
myeloid cell developmentGO:0061515320.010

spns1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.059
disease of metabolismDOID:001466700.059
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016
cardiovascular system diseaseDOID:128700.015
lysosomal storage diseaseDOID:321100.010