Danio rerio

46 known processes

dcn

decorin

(Aliases: DC)

dcn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.760
Zebrafish
collagen fibril organizationGO:003019910.681
Zebrafish
chordate embryonic developmentGO:00430092710.553
extracellular structure organizationGO:0043062270.524
Zebrafish
skeletal system developmentGO:00015011810.522
cellular component morphogenesisGO:00329893360.460
transcription dna templatedGO:00063511810.450
connective tissue developmentGO:0061448990.427
embryonic organ developmentGO:00485683810.388
Zebrafish
convergent extensionGO:00600261180.349
response to chemicalGO:00422213200.343
Rat
response to mechanical stimulusGO:0009612240.330
Rat
response to nutrientGO:000758430.311
eye developmentGO:00016542770.301
Zebrafish
regulation of multicellular organismal developmentGO:20000262230.296
morphogenesis of an epitheliumGO:00020093330.283
cartilage developmentGO:0051216960.273
wound healingGO:0042060900.268
Rat
negative regulation of cellular processGO:00485232830.267
chondrocyte developmentGO:000206340.255
response to drugGO:004249330.255
aromatic compound biosynthetic processGO:00194382170.254
notochord developmentGO:0030903540.254
regulation of stem cell differentiationGO:200073640.232
response to amino acidGO:004320020.228
response to vitaminGO:003327330.225
appendage morphogenesisGO:0035107560.222
fin morphogenesisGO:0033334530.218
extracellular matrix organizationGO:0030198270.214
Zebrafish
embryonic organ morphogenesisGO:00485622740.212
Zebrafish
regionalizationGO:00030022740.203
macromolecule biosynthetic processGO:00090592270.198
tube morphogenesisGO:00352393490.194
positive regulation of biological processGO:00485182530.189
tissue regenerationGO:0042246740.185
regulation of cellular macromolecule biosynthetic processGO:20001122220.181
multicellular organismal macromolecule metabolic processGO:004425920.181
cell morphogenesis involved in neuron differentiationGO:00486671630.177
blood vessel developmentGO:00015682460.175
neurological system processGO:0050877620.168
fin regenerationGO:0031101510.159
response to external stimulusGO:00096052640.156
Rat
central nervous system developmentGO:00074173870.153
outflow tract morphogenesisGO:000315110.149
response to hexoseGO:000974630.147
negative regulation of biological processGO:00485193040.146
regenerationGO:0031099910.146
multicellular organismal metabolic processGO:004423620.145
cellular response to retinoic acidGO:007130010.145
muscle structure developmentGO:00610611960.144
Rat
inner ear developmentGO:00488391260.139
positive regulation of signalingGO:0023056560.138
fin developmentGO:0033333770.137
positive regulation of cellular processGO:00485222010.135
regulation of nucleobase containing compound metabolic processGO:00192192500.133
cartilage morphogenesisGO:0060536130.130
digestive tract developmentGO:00485652650.130
cell morphogenesisGO:00009022890.127
inner ear morphogenesisGO:0042472630.126
head developmentGO:00603223030.125
response to corticosteroidGO:003196010.123
formation of primary germ layerGO:0001704620.123
digestive tract morphogenesisGO:00485462310.121
positive regulation of mesenchymal cell proliferationGO:000205310.121
positive regulation of canonical wnt signaling pathwayGO:009026340.116
pectoral fin developmentGO:0033339500.116
mesenchymal cell differentiationGO:0048762870.112
positive regulation of stem cell proliferationGO:200064810.110
neuron differentiationGO:00301823530.107
cell morphogenesis involved in differentiationGO:00009041950.101
regulation of extrinsic apoptotic signaling pathwayGO:200123630.095
response to endogenous stimulusGO:0009719830.094
heterocycle biosynthetic processGO:00181302150.093
system processGO:00030081850.091
regulation of gene expressionGO:00104682650.088
multicellular organismal signalingGO:0035637220.087
skin morphogenesisGO:004358970.086
direct ossificationGO:003607230.082
regulation of synapse assemblyGO:005196330.081
skeletal system morphogenesisGO:00487051020.080
regulation of cell adhesionGO:0030155150.080
mesenchymal cell developmentGO:0014031780.080
regulation of cell communicationGO:00106462320.079
negative regulation of bmp signaling pathwayGO:0030514130.078
response to organic substanceGO:00100331530.078
Rat
signal transductionGO:00071654550.078
response to alcoholGO:0097305140.077
positive regulation of cell adhesionGO:004578510.077
anterior posterior pattern specificationGO:00099521520.077
cellular response to external stimulusGO:007149620.077
protein localization to nucleusGO:003450430.076
epithelial to mesenchymal transitionGO:0001837210.076
cellular ketone metabolic processGO:0042180110.075
embryo development ending in birth or egg hatchingGO:00097922710.075
response to stressGO:00069502630.074
Rat
regulation of epithelial to mesenchymal transitionGO:001071730.072
phagocytosisGO:000690930.071
regulation of anatomical structure morphogenesisGO:00226031300.070
transportGO:00068102200.070
response to woundingGO:00096111160.070
Rat
vasculature developmentGO:00019442780.069
regulation of macromolecule biosynthetic processGO:00105562250.069
extrinsic apoptotic signaling pathwayGO:009719130.069
regulation of biosynthetic processGO:00098892500.067
response to abiotic stimulusGO:00096281220.067
Rat
regulation of cell substrate adhesionGO:001081010.067
liver developmentGO:0001889960.067
protein trimerizationGO:007020640.066
regulation of cell differentiationGO:00455951420.066
cellular nitrogen compound biosynthetic processGO:00442712180.066
macrophage chemotaxisGO:004824630.065
intramembranous ossificationGO:000195730.065
biosynthetic processGO:00090582940.064
muscle organ developmentGO:00075171010.062
Rat
trabecula formationGO:006034320.062
cell projection organizationGO:00300302840.062
ear developmentGO:00435831270.062
positive regulation of cytokine productionGO:000181920.061
growthGO:00400071740.060
negative regulation of gastrulationGO:2000542110.059
regulation of cellular component organizationGO:0051128860.057
protein polymerizationGO:005125840.056
rna metabolic processGO:00160702190.055
regulation of rna biosynthetic processGO:20011412130.055
regulation of nucleic acid templated transcriptionGO:19035062130.055
response to inorganic substanceGO:0010035380.054
regulation of response to stimulusGO:00485832690.054
positive regulation of epithelial cell migrationGO:001063420.054
response to growth factorGO:0070848390.054
regulation of cell deathGO:00109411030.054
appendage developmentGO:0048736800.053
positive regulation of cell substrate adhesionGO:001081110.053
regulation of chondrocyte differentiationGO:003233010.053
bleb assemblyGO:003206010.052
regulation of rna metabolic processGO:00512522240.052
convergent extension involved in gastrulationGO:0060027710.052
negative regulation of embryonic developmentGO:0045992110.050
somitogenesisGO:0001756870.050
collagen metabolic processGO:003296320.049
mesenchymal cell proliferationGO:001046310.049
cellular response to extracellular stimulusGO:003166820.049
regulation of signalingGO:00230512350.048
peptidyl serine modificationGO:001820920.048
Mouse
regulation of multicellular organismal processGO:00512392770.048
cellular aromatic compound metabolic processGO:00067252950.048
regulation of synapse organizationGO:005080730.047
ossificationGO:0001503230.047
endochondral bone morphogenesisGO:006035080.047
regulation of mesenchymal cell proliferationGO:001046410.046
embryonic skeletal system developmentGO:0048706970.046
heart joggingGO:0003146400.046
regulation of cellular biosynthetic processGO:00313262450.045
negative regulation of macromolecule metabolic processGO:0010605760.045
cellular response to organic substanceGO:00713101050.045
myelin assemblyGO:003228810.045
positive regulation of immune system processGO:0002684170.045
heterocycle metabolic processGO:00464832900.045
meiotic nuclear divisionGO:000712640.044
heart morphogenesisGO:00030071560.044
nucleic acid templated transcriptionGO:00976591810.044
retina morphogenesis in camera type eyeGO:0060042790.044
rna biosynthetic processGO:00327741810.043
regulation of transcription dna templatedGO:00063552130.043
cell deathGO:00082191210.043
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.042
response to glucocorticoidGO:005138410.042
nucleic acid metabolic processGO:00903042440.042
cellular response to endogenous stimulusGO:0071495680.042
response to monosaccharideGO:003428430.041
positive regulation of response to stimulusGO:0048584800.041
cardiac ventricle developmentGO:000323190.041
gland developmentGO:00487321430.041
sympathetic ganglion developmentGO:006154920.041
canonical wnt signaling pathwayGO:0060070480.040
cellular response to growth factor stimulusGO:0071363390.040
regulation of developmental processGO:00507932470.040
gene expressionGO:00104672520.039
myelinationGO:0042552180.039
sensory organ morphogenesisGO:00905962000.039
Zebrafish
cellular response to chemical stimulusGO:00708871570.039
embryonic cranial skeleton morphogenesisGO:0048701900.039
positive regulation of immune effector processGO:000269930.038
negative regulation of multicellular organismal processGO:0051241690.038
cellular component movementGO:00069283350.038
regulation of signal transductionGO:00099662250.038
cardiac atrium developmentGO:000323040.038
nucleobase containing compound metabolic processGO:00061392740.038
pharyngeal system developmentGO:0060037180.037
dorsal ventral pattern formationGO:00099531250.037
stem cell differentiationGO:00488631170.037
embryonic limb morphogenesisGO:003032620.035
cell substrate adhesionGO:003158940.035
brain developmentGO:00074202930.035
response to oxygen levelsGO:0070482250.035
cellular component assemblyGO:00226071700.035
negative regulation of feeding behaviorGO:200025220.034
hepaticobiliary system developmentGO:0061008980.034
regulation of erk1 and erk2 cascadeGO:007037240.034
regulation of cell activationGO:005086510.034
regulation of cellular amino acid metabolic processGO:000652100.034
cellular macromolecule biosynthetic processGO:00346452240.033
regulation of epithelial cell proliferationGO:005067830.033
regulation of striated muscle contractionGO:000694220.033
chronic inflammatory responseGO:000254410.033
regulation of wnt signaling pathwayGO:0030111530.033
wnt signaling pathwayGO:0016055800.033
regulation of cellular metabolic processGO:00313233200.033
negative regulation of endodermal cell differentiationGO:190322580.032
negative regulation of cell deathGO:0060548600.032
cellular component disassemblyGO:002241110.032
cell part morphogenesisGO:00329902460.032
response to oxygen containing compoundGO:1901700550.032
Rat
negative regulation of cellular metabolic processGO:0031324770.032
cardiac atrium morphogenesisGO:000320920.032
heart developmentGO:00075073130.032
developmental growthGO:00485891660.032
cell projection assemblyGO:0030031640.032
epithelial tube morphogenesisGO:00605621480.031
collagen biosynthetic processGO:003296420.031
gastrulationGO:00073692080.031
positive regulation of metabolic processGO:00098931080.031
cellular component biogenesisGO:00440851780.031
cellular macromolecule metabolic processGO:00442603910.030
positive regulation of cellular component movementGO:0051272110.030
segmentationGO:0035282970.030
action potentialGO:0001508190.029
response to hormoneGO:0009725480.029
tissue migrationGO:0090130370.029
positive regulation of endothelial cell migrationGO:001059520.028
neuronal action potentialGO:0019228180.028
regulation of cell morphogenesisGO:0022604420.028
nucleobase containing compound biosynthetic processGO:00346542050.028
regulation of macromolecule metabolic processGO:00602553170.028
nitrogen compound metabolic processGO:00068073190.027
regulation of primary metabolic processGO:00800903110.027
skin developmentGO:0043588540.027
retina development in camera type eyeGO:00600411460.027
muscle fiber developmentGO:0048747520.027
primary neural tube formationGO:001402010.027
muscle cell developmentGO:00550011150.027
cardiac chamber morphogenesisGO:0003206120.027
cell migrationGO:00164772370.026
cell fate specificationGO:0001708680.026
hematopoietic or lymphoid organ developmentGO:00485341910.026
erk1 and erk2 cascadeGO:007037140.026
sympathetic nervous system developmentGO:004848530.026
regulation of cell developmentGO:00602841000.026
axonogenesisGO:00074091520.026
stem cell developmentGO:0048864820.025
ear morphogenesisGO:0042471640.025
neuron projection morphogenesisGO:00488121610.025
cell adhesionGO:0007155400.025
generation of neuronsGO:00486993850.025
face morphogenesisGO:006032560.025
bone morphogenesisGO:0060349110.025
regulation of multicellular organism growthGO:004001440.025
response to lipidGO:0033993600.025
Rat
sensory perception of mechanical stimulusGO:0050954160.024
camera type eye developmentGO:00430102220.024
Zebrafish
cell projection morphogenesisGO:00488582440.024
positive regulation of signal transductionGO:0009967560.024
positive regulation of erk1 and erk2 cascadeGO:007037420.024
striated muscle contractionGO:0006941120.024
macromolecule modificationGO:00434121110.024
Mouse
positive regulation of cytosolic calcium ion concentrationGO:000720440.023
regulation of localizationGO:00328791040.023
craniofacial suture morphogenesisGO:009709420.023
biological adhesionGO:0022610400.023
morphogenesis of an epithelial sheetGO:0002011490.023
blood vessel morphogenesisGO:00485142160.023
nucleoside monophosphate catabolic processGO:000912540.023
endodermal cell differentiationGO:0035987190.022
negative regulation of signalingGO:0023057960.022
ameboidal type cell migrationGO:00016671430.022
cognitionGO:005089010.022
response to acid chemicalGO:0001101170.022
skeletal muscle organ developmentGO:0060538780.022
Rat
regulation of embryonic developmentGO:0045995470.022
regulation of protein localization to nucleusGO:190018020.021
negative regulation of metabolic processGO:0009892860.021
regulation of bmp signaling pathwayGO:0030510390.021
establishment of localization in cellGO:0051649770.021
positive regulation of cell activationGO:005086710.021
angiogenesisGO:00015251580.021
cellular protein metabolic processGO:00442671290.021
Mouse
deathGO:00162651210.021
regulation of biological qualityGO:00650082630.021
cellular protein modification processGO:00064641000.020
Mouse
negative regulation of gene expressionGO:0010629650.020
specification of organ identityGO:001009220.020
positive regulation of gene expressionGO:0010628710.020
endoderm developmentGO:0007492490.020
camera type eye morphogenesisGO:00485931080.020
Zebrafish
regulation of cellular amine metabolic processGO:003323800.020
regulation of immune responseGO:0050776140.020
positive regulation of cell communicationGO:0010647560.019
regulation of endodermal cell differentiationGO:1903224150.019
embryonic digestive tract developmentGO:004856640.019
regulation of non canonical wnt signaling pathwayGO:200005070.019
regulation of cellular ketone metabolic processGO:001056570.019
negative regulation of nitrogen compound metabolic processGO:0051172590.019
regulation of cytokine productionGO:000181730.019
regulation of muscle contractionGO:000693730.019
regulation of nitrogen compound metabolic processGO:00511712510.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.019
regulation of chronic inflammatory responseGO:000267610.019
regulation of cell morphogenesis involved in differentiationGO:0010769380.018
regulation of stem cell proliferationGO:007209120.018
negative regulation of epithelial cell proliferationGO:005068010.018
enzyme linked receptor protein signaling pathwayGO:00071671060.018
cellular amine metabolic processGO:004410620.018
negative regulation of dna metabolic processGO:005105340.018
cell surface receptor signaling pathwayGO:00071663250.018
glial cell migrationGO:000834730.018
negative regulation of mesoderm developmentGO:200038150.018
zymogen activationGO:003163830.018
medial fin developmentGO:0033338160.018
regulation of protein transportGO:005122330.018
atrioventricular valve developmentGO:0003171110.018
positive regulation of multicellular organismal processGO:0051240520.018
digestive system developmentGO:00551232890.018
hard palate developmentGO:006002240.017
endodermal digestive tract morphogenesisGO:006103120.017
neuron projection developmentGO:00311751800.017
cellular nitrogen compound metabolic processGO:00346412900.017
atp catabolic processGO:000620040.017
response to steroid hormoneGO:0048545350.017
regulation of dna replicationGO:000627530.017
organic substance biosynthetic processGO:19015762890.017
response to carbohydrateGO:000974330.017
somite developmentGO:0061053960.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of behaviorGO:0050795240.017
negative regulation of dna replicationGO:000815620.016
positive regulation of lipase activityGO:006019310.016
carboxylic acid metabolic processGO:0019752220.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.016
protein metabolic processGO:00195381830.016
negative regulation of synapse assemblyGO:005196420.016
protein importGO:001703830.016
anterior posterior axis specificationGO:0009948200.016
positive regulation of cell migrationGO:0030335110.016
protein modification processGO:00362111000.016
Mouse
response to nitrogen compoundGO:1901698190.016
embryonic skeletal system morphogenesisGO:0048704930.016
embryonic eye morphogenesisGO:0048048300.016
Zebrafish
regulation of blood pressureGO:000821710.016
regulation of cardiac muscle contractionGO:005511720.015
regulation of cytoplasmic transportGO:190364940.015
bmp signaling pathwayGO:0030509520.015
transcription from rna polymerase ii promoterGO:0006366800.015
wnt signaling pathway planar cell polarity pathwayGO:006007140.015
synaptic growth at neuromuscular junctionGO:005112420.015
cell matrix adhesionGO:000716040.015
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
glucose homeostasisGO:004259310.015
regulation of vasculature developmentGO:1901342330.015
regulation of nervous system developmentGO:0051960900.015
negative regulation of response to dna damage stimulusGO:200102130.015
cellular component assembly involved in morphogenesisGO:00109271070.014
establishment of protein localization to organelleGO:007259440.014
respiratory system developmentGO:006054150.014
nerve developmentGO:0021675450.014
epithelium migrationGO:0090132250.014
response to fibroblast growth factorGO:0071774220.014
negative regulation of protein phosphorylationGO:000193340.014
mesenchyme developmentGO:00604851270.014
endoderm formationGO:0001706290.014
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.014
single organism metabolic processGO:00447102170.014
trabecula morphogenesisGO:006138320.014
enteric nervous system developmentGO:0048484120.014
epithelial cell migrationGO:0010631250.014
glial cell differentiationGO:0010001420.014
regulation of cell migrationGO:0030334400.014
tube closureGO:006060610.014
negative regulation of mesodermal cell fate specificationGO:004266230.014
negative regulation of developmental processGO:0051093650.014
determination of heart left right asymmetryGO:00613711170.013
organic cyclic compound biosynthetic processGO:19013622230.013
locus ceruleus developmentGO:002170330.013
regulation of metabolic processGO:00192223590.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
peptidyl lysine acetylationGO:001839420.013
regulation of endothelial cell proliferationGO:000193610.013
regulation of canonical wnt signaling pathwayGO:0060828340.013
regulation of protein targetingGO:190353320.013
neural retina developmentGO:0003407490.013
ensheathment of neuronsGO:0007272180.013
cellular response to vitaminGO:007129510.013
organic acid metabolic processGO:0006082310.013
notch signaling pathwayGO:0007219350.013
ribonucleoside monophosphate catabolic processGO:000915840.013
regulation of reactive oxygen species metabolic processGO:200037720.013
regulation of programmed cell deathGO:00430671010.013
hindbrain developmentGO:0030902910.013
positive regulation of cell motilityGO:2000147110.013
cellular localizationGO:0051641970.013
wnt signaling pathway involved in somitogenesisGO:009024420.012
cytoplasm organizationGO:000702840.012
cell motilityGO:00488702440.012
embryonic digestive tract morphogenesisGO:004855730.012
cell migration involved in gastrulationGO:0042074790.012
embryonic viscerocranium morphogenesisGO:0048703520.012
establishment of localizationGO:00512342440.012
response to hydrogen peroxideGO:004254230.012
positive regulation of developmental processGO:0051094500.012
muscle tissue developmentGO:00605371100.012
Rat
single organism organelle organizationGO:19025891990.012
regulation of bindingGO:005109830.012
oxoacid metabolic processGO:0043436310.012
heart contractionGO:0060047710.012
protein homooligomerizationGO:005126030.012
homeostatic processGO:00425921420.012
limb bud formationGO:006017420.012
extracellular matrix constituent secretionGO:007027830.012
positive regulation of transcription dna templatedGO:0045893570.012
eye morphogenesisGO:00485921440.012
Zebrafish
cell proliferationGO:0008283800.012
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.012
negative regulation of jun kinase activityGO:004350810.012
posttranscriptional regulation of gene expressionGO:0010608140.012
negative regulation of cell developmentGO:0010721260.012
regulation of establishment of planar polarityGO:009017540.012
growth plate cartilage developmentGO:000341720.012
positive regulation of wnt signaling pathwayGO:0030177130.012
positive regulation of histone deacetylationGO:003106510.011
cartilage condensationGO:000150230.011
regulation of ossificationGO:003027850.011
heart loopingGO:0001947940.011
cell growthGO:0016049570.011
negative regulation of leukocyte differentiationGO:190210610.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of angiogenesisGO:0045765260.011
regulation of cellular component movementGO:0051270550.011
defense response to fungusGO:005083220.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
regulation of cell motilityGO:2000145460.011
otolith morphogenesisGO:003247480.011
response to extracellular stimulusGO:0009991100.011
regulation of apoptotic processGO:0042981980.011
positive regulation of macromolecule metabolic processGO:0010604930.011
organic substance transportGO:0071702580.011
cardiac ventricle morphogenesisGO:000320870.010
purine ribonucleoside monophosphate catabolic processGO:000916940.010
response to xenobiotic stimulusGO:0009410450.010
polarized epithelial cell differentiationGO:003085940.010
positive regulation of cellular component biogenesisGO:004408930.010
cranial suture morphogenesisGO:006036310.010
hemopoiesisGO:00300971830.010
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.010
protein acylationGO:004354330.010
face developmentGO:006032480.010
circulatory system processGO:0003013870.010
leukocyte proliferationGO:007066110.010

dcn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.175
neuromuscular diseaseDOID:44000.175
neuropathyDOID:87000.175
charcot marie tooth disease type 4DOID:005054100.175
charcot marie tooth diseaseDOID:1059500.175
disease of anatomical entityDOID:700.175
connective tissue diseaseDOID:6500.171
bone remodeling diseaseDOID:008000500.171
bone diseaseDOID:008000100.171
musculoskeletal system diseaseDOID:1700.171
osteogenesis imperfectaDOID:1234700.094
bone development diseaseDOID:008000600.094
osteochondrodysplasiaDOID:225600.094
bone resorption diseaseDOID:008001100.046
osteoporosisDOID:1147600.046
immune system diseaseDOID:291400.042