Danio rerio

0 known processes

pdcd8

programmed cell death 8 (apoptosis-inducing factor)

(Aliases: AIF,zgc:91994)

pdcd8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.203
Worm
organic acid catabolic processGO:001605430.112
mitochondrion organizationGO:000700540.104
Human
regulation of multicellular organism growthGO:004001440.080
carboxylic acid catabolic processGO:004639530.061
nucleic acid metabolic processGO:00903042440.058
Mouse Worm
double strand break repairGO:000630230.058
agingGO:000756820.055
cellular aromatic compound metabolic processGO:00067252950.055
Mouse Worm
amine metabolic processGO:000930820.053
multicellular organism growthGO:003526440.052
intra s dna damage checkpointGO:003157310.051
cellular biosynthetic processGO:00442492860.049
mitotic dna damage checkpointGO:004477340.043
alpha amino acid metabolic processGO:190160530.041
stem cell proliferationGO:007208940.040
meiotic nuclear divisionGO:000712640.040
maintenance of locationGO:005123540.039
regulation of mrna processingGO:005068430.039
organic substance biosynthetic processGO:19015762890.038
cellular amine metabolic processGO:004410620.038
meiotic cell cycle processGO:190304630.037
lipid oxidationGO:003444010.036
lipid catabolic processGO:001604240.035
coenzyme biosynthetic processGO:000910820.035
chromosome organization involved in meiosisGO:007019210.034
blood vessel morphogenesisGO:00485142160.034
nucleotide metabolic processGO:0009117280.034
somatic muscle developmentGO:000752540.033
macromolecule biosynthetic processGO:00090592270.033
positive regulation of cellular catabolic processGO:003133130.033
lipid storageGO:001991510.032
central nervous system developmentGO:00074173870.032
negative regulation of cellular processGO:00485232830.032
cell deathGO:00082191210.032
Human Mouse Worm
cofactor biosynthetic processGO:0051188100.031
small molecule metabolic processGO:0044281770.031
adherens junction organizationGO:003433240.030
regulation of cellular amine metabolic processGO:003323800.030
dicarboxylic acid metabolic processGO:004364810.029
cellular macromolecule metabolic processGO:00442603910.028
Human Mouse Worm
apoptotic processGO:00069151160.028
Human Mouse Worm
nuclear transportGO:005116940.026
vasculature developmentGO:00019442780.026
organonitrogen compound metabolic processGO:1901564740.025
protein stabilizationGO:005082120.025
cellular protein modification processGO:00064641000.025
cellular amino acid metabolic processGO:000652070.025
regulation of peptidase activityGO:0052547230.025
Human
organelle organizationGO:00069962270.025
Human
cell projection organizationGO:00300302840.024
cellular lipid catabolic processGO:004424230.024
sister chromatid cohesionGO:000706220.024
regulation of programmed cell deathGO:00430671010.024
Human Mouse
regulation of cellular metabolic processGO:00313233200.024
Human Mouse
biosynthetic processGO:00090582940.024
locomotionGO:00400113130.024
regulation of glucose transportGO:001082710.023
meiosis iGO:000712710.023
protein metabolic processGO:00195381830.023
Human
regulation of cellular amino acid metabolic processGO:000652100.023
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
fatty acid transportGO:001590810.023
mitotic g2 dna damage checkpointGO:000709530.022
regulation of establishment of protein localizationGO:007020140.022
organic acid metabolic processGO:0006082310.022
cellular component morphogenesisGO:00329893360.022
protein modification processGO:00362111000.022
cellular response to oxygen levelsGO:007145310.022
neuronal action potentialGO:0019228180.022
cell substrate adhesionGO:003158940.022
regulation of protein transportGO:005122330.021
mitotic g2 m transition checkpointGO:004481830.021
positive regulation of catabolic processGO:000989640.021
blood vessel developmentGO:00015682460.021
single organism metabolic processGO:00447102170.021
Human Mouse
cellular ketone metabolic processGO:0042180110.021
monocarboxylic acid catabolic processGO:007232930.021
small molecule catabolic processGO:004428230.020
embryo development ending in birth or egg hatchingGO:00097922710.020
Worm
aromatic compound biosynthetic processGO:00194382170.020
establishment of protein localization to organelleGO:007259440.020
cellular macromolecule biosynthetic processGO:00346452240.020
positive regulation of nucleoside metabolic processGO:004597910.020
regulation of nitrogen compound metabolic processGO:00511712510.020
Mouse
response to chemicalGO:00422213200.020
embryonic heart tube developmentGO:00350501330.019
oxidative phosphorylationGO:000611910.019
regulation of metabolic processGO:00192223590.019
Human Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.019
response to stressGO:00069502630.019
Mouse
catechol containing compound metabolic processGO:000971220.019
regulation of macromolecule biosynthetic processGO:00105562250.019
negative regulation of catabolic processGO:000989530.019
cell cycleGO:0007049930.018
regulation of cellular biosynthetic processGO:00313262450.018
embryonic organ developmentGO:00485683810.018
autophagyGO:000691440.018
cellular amino acid biosynthetic processGO:000865220.018
protein acetylationGO:000647320.018
proteolysisGO:0006508380.018
Human
regulation of multicellular organismal processGO:00512392770.018
positive regulation of transportGO:005105020.018
system processGO:00030081850.018
regulation of biosynthetic processGO:00098892500.018
response to uvGO:000941130.018
neurotransmitter transportGO:000683620.018
positive regulation of cellular amine metabolic processGO:003324000.018
protein processingGO:0016485120.018
Human
electron transport chainGO:002290020.018
ion transportGO:00068111140.018
adult behaviorGO:003053420.018
regulation of intracellular protein transportGO:003315730.017
angiogenesisGO:00015251580.017
regulation of cytoplasmic transportGO:190364940.017
organic cyclic compound biosynthetic processGO:19013622230.017
modification dependent protein catabolic processGO:001994130.017
positive regulation of cell adhesionGO:004578510.017
regulation of organ growthGO:004662030.017
long chain fatty acid transportGO:001590910.017
regulation of reproductive processGO:200024140.017
gene expressionGO:00104672520.017
Human
branched chain amino acid metabolic processGO:000908110.017
positive regulation of biological processGO:00485182530.017
Human Mouse
modification dependent macromolecule catabolic processGO:004363230.017
regulation of protein catabolic processGO:004217610.017
phagocytosisGO:000690930.017
cellular response to stressGO:0033554620.016
Mouse
cognitionGO:005089010.016
regulation of blood pressureGO:000821710.016
mitochondrial transportGO:000683920.016
gtp metabolic processGO:004603940.016
reactive nitrogen species metabolic processGO:200105700.016
protein acylationGO:004354330.016
regulation of cell matrix adhesionGO:000195210.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
regulation of nucleobase containing compound metabolic processGO:00192192500.016
Mouse
negative regulation of dna metabolic processGO:005105340.015
synaptic growth at neuromuscular junctionGO:005112420.015
reactive oxygen species biosynthetic processGO:190340910.015
glucose importGO:004632320.015
rna metabolic processGO:00160702190.015
cellular protein metabolic processGO:00442671290.015
Human
amino acid transportGO:000686520.015
mitochondrion morphogenesisGO:007058420.015
positive regulation of cellular processGO:00485222010.015
Human Mouse
negative regulation of biological processGO:00485193040.015
peptidyl threonine phosphorylationGO:001810710.015
gtp catabolic processGO:000618420.015
protein maturationGO:0051604120.015
Human
peptidyl serine phosphorylationGO:001810510.015
regulation of glucose importGO:004632410.015
response to carbohydrateGO:000974330.015
action potentialGO:0001508190.015
cell part morphogenesisGO:00329902460.015
ubiquitin dependent protein catabolic processGO:000651130.014
membrane invaginationGO:001032410.014
response to hexoseGO:000974630.014
cellular response to starvationGO:000926710.014
regulation of cell deathGO:00109411030.014
Human Mouse
multicellular organismal metabolic processGO:004423620.014
eye developmentGO:00016542770.014
carboxylic acid metabolic processGO:0019752220.014
regulation of gtpase activityGO:004308720.014
hydrogen peroxide metabolic processGO:004274320.014
nucleobase containing compound transportGO:001593120.014
regulation of synaptic plasticityGO:004816710.014
negative regulation of kinase activityGO:003367340.014
regulation of dna replicationGO:000627530.014
nitric oxide metabolic processGO:004620920.014
appendage developmentGO:0048736800.014
cellular response to nutrient levelsGO:003166920.014
chordate embryonic developmentGO:00430092710.014
transmission of nerve impulseGO:0019226190.014
regulation of reactive oxygen species metabolic processGO:200037720.014
nucleocytoplasmic transportGO:000691340.014
positive regulation of cell cycleGO:004578730.014
peptidyl serine modificationGO:001820920.013
zymogen activationGO:003163830.013
Human
nuclear migrationGO:000709730.013
fatty acid beta oxidationGO:000663510.013
morphogenesis of an epitheliumGO:00020093330.013
medulla oblongata developmentGO:002155040.013
protein importGO:001703830.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.013
Human
head developmentGO:00603223030.013
spermatid developmentGO:000728620.013
mitotic dna integrity checkpointGO:004477440.013
protein complex disassemblyGO:004324110.013
anion transportGO:0006820380.013
cellular component movementGO:00069283350.013
regulation of neural precursor cell proliferationGO:200017730.013
nuclear exportGO:005116810.013
single organism organelle organizationGO:19025891990.013
regulation of cellular ketone metabolic processGO:001056570.013
response to nutrientGO:000758430.013
rna 3 end processingGO:003112320.013
regulation of gtp catabolic processGO:003312420.013
regulation of developmental processGO:00507932470.013
negative regulation of synapse assemblyGO:005196420.013
atp synthesis coupled electron transportGO:004277310.013
purine containing compound metabolic processGO:0072521290.013
alcohol biosynthetic processGO:004616520.012
cofactor metabolic processGO:0051186150.012
negative regulation of protein phosphorylationGO:000193340.012
digestive system developmentGO:00551232890.012
camera type eye developmentGO:00430102220.012
endosomal transportGO:001619720.012
phagocytosis engulfmentGO:000691110.012
regulation of cell migration involved in sprouting angiogenesisGO:009004930.012
epithelial tube morphogenesisGO:00605621480.012
multicellular organismal signalingGO:0035637220.012
regulation of synapse organizationGO:005080730.012
regulation of nucleoside metabolic processGO:000911820.012
phosphorus metabolic processGO:00067931090.012
negative regulation of cellular catabolic processGO:003133030.012
regulation of autophagyGO:001050630.012
macromolecular complex disassemblyGO:003298410.012
proteasomal protein catabolic processGO:001049820.012
regulation of blood vessel sizeGO:005088020.012
rna export from nucleusGO:000640510.012
ketone biosynthetic processGO:004218120.012
macroautophagyGO:001623610.012
regulation of stem cell proliferationGO:007209120.012
nucleoside monophosphate catabolic processGO:000912540.012
mitotic cell cycle processGO:1903047480.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
cellular response to reactive oxygen speciesGO:003461420.012
response to external stimulusGO:00096052640.012
cellular response to extracellular stimulusGO:003166820.012
lateral inhibitionGO:004633110.012
proteolysis involved in cellular protein catabolic processGO:005160330.012
establishment of rna localizationGO:005123630.012
nitrogen compound metabolic processGO:00068073190.012
Mouse Worm
smooth muscle contractionGO:000693920.012
spermatid differentiationGO:004851520.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
production of molecular mediator of immune responseGO:000244020.011
sprouting angiogenesisGO:0002040530.011
regulation of gene expressionGO:00104682650.011
thioester metabolic processGO:003538310.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
single organism nuclear importGO:190259330.011
negative regulation of dna replicationGO:000815620.011
monoamine transportGO:001584410.011
protein localization to plasma membraneGO:007265910.011
organic cyclic compound metabolic processGO:19013603010.011
Mouse Worm
rna transportGO:005065820.011
urogenital system developmentGO:0001655970.011
developmental growthGO:00485891660.011
determination of bilateral symmetryGO:00098552040.011
response to drugGO:004249330.011
establishment of localization in cellGO:0051649770.011
Worm
purine nucleotide metabolic processGO:0006163270.011
mitotic cell cycleGO:0000278640.011
brain developmentGO:00074202930.011
cell substrate junction assemblyGO:000704420.011
nucleobase containing compound metabolic processGO:00061392740.011
Mouse Worm
cell matrix adhesionGO:000716040.011
regulation of cell substrate adhesionGO:001081010.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
ribonucleoside monophosphate catabolic processGO:000915840.011
regulation of cell communicationGO:00106462320.011
positive regulation of nucleotide catabolic processGO:003081310.011
dna templated transcription elongationGO:000635430.010
nucleic acid transportGO:005065720.010
nitric oxide biosynthetic processGO:000680920.010
carbohydrate homeostasisGO:003350010.010
digestive tract developmentGO:00485652650.010
negative regulation of protein processingGO:0010955100.010
acyl coa metabolic processGO:000663710.010
regulation of response to extracellular stimulusGO:003210410.010
determination of left right symmetryGO:00073681790.010
hemopoiesisGO:00300971830.010
fatty acid catabolic processGO:000906210.010
cell motilityGO:00488702440.010
catecholamine metabolic processGO:000658420.010
specification of symmetryGO:00097992040.010
tissue remodelingGO:004877140.010
cellular protein complex disassemblyGO:004362410.010
protein dephosphorylationGO:000647030.010
single organism biosynthetic processGO:0044711710.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010

pdcd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.431
inherited metabolic disorderDOID:65500.431
amino acid metabolic disorderDOID:925200.048
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
organ system cancerDOID:005068600.018
disease of anatomical entityDOID:700.016
Human
nervous system diseaseDOID:86300.016
Human
mitochondrial metabolism diseaseDOID:70000.011
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011
musculoskeletal system diseaseDOID:1700.010