Danio rerio

51 known processes

pdcd2

programmed cell death 2

(Aliases: MGC63685,zgc:63685)

pdcd2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hemopoiesisGO:00300971830.798
innate immune response activating signal transductionGO:000275850.747
immune system developmentGO:00025201910.629
activation of immune responseGO:000225390.603
hematopoietic or lymphoid organ developmentGO:00485341910.572
erythrocyte differentiationGO:0030218540.545
cellular nitrogen compound metabolic processGO:00346412900.540
cellular aromatic compound metabolic processGO:00067252950.529
positive regulation of innate immune responseGO:004508980.514
organic cyclic compound metabolic processGO:19013603010.514
nitrogen compound metabolic processGO:00068073190.511
immune response regulating signaling pathwayGO:000276450.508
immune system processGO:00023762410.492
myeloid cell differentiationGO:0030099860.486
regulation of biological qualityGO:00650082630.463
cellular macromolecule metabolic processGO:00442603910.463
regulation of defense responseGO:0031347140.456
heterocycle metabolic processGO:00464832900.446
organic cyclic compound biosynthetic processGO:19013622230.416
cellular macromolecule biosynthetic processGO:00346452240.408
biosynthetic processGO:00090582940.355
organic substance biosynthetic processGO:19015762890.348
cellular biosynthetic processGO:00442492860.330
regulation of multicellular organismal developmentGO:20000262230.330
homeostatic processGO:00425921420.316
rna metabolic processGO:00160702190.302
gene expressionGO:00104672520.301
blood vessel developmentGO:00015682460.291
myeloid leukocyte differentiationGO:0002573150.285
regulation of nucleobase containing compound metabolic processGO:00192192500.281
regulation of gene expressionGO:00104682650.270
transcription dna templatedGO:00063511810.264
heterocycle biosynthetic processGO:00181302150.263
positive regulation of defense responseGO:003134990.258
nucleic acid metabolic processGO:00903042440.248
regulation of primary metabolic processGO:00800903110.220
definitive hemopoiesisGO:0060216180.215
signal transductionGO:00071654550.198
immune response activating signal transductionGO:000275750.198
regulation of macromolecule biosynthetic processGO:00105562250.194
nucleic acid templated transcriptionGO:00976591810.190
macromolecule biosynthetic processGO:00090592270.184
cellular component morphogenesisGO:00329893360.181
angiogenesisGO:00015251580.180
toll like receptor signaling pathwayGO:000222440.179
digestive tract morphogenesisGO:00485462310.179
erythrocyte homeostasisGO:0034101550.169
convergent extensionGO:00600261180.169
regulation of rna metabolic processGO:00512522240.169
nucleobase containing compound metabolic processGO:00061392740.163
leukocyte differentiationGO:0002521250.162
primitive erythrocyte differentiationGO:006031950.145
regulation of macromolecule metabolic processGO:00602553170.144
response to stressGO:00069502630.142
cell morphogenesis involved in neuron differentiationGO:00486671630.140
regulation of synapse assemblyGO:005196330.139
regulation of cell communicationGO:00106462320.139
response to external biotic stimulusGO:0043207970.138
b cell differentiationGO:003018310.138
cellular nitrogen compound biosynthetic processGO:00442712180.137
activation of innate immune responseGO:000221860.137
locomotionGO:00400113130.137
response to biotic stimulusGO:0009607970.136
cell projection organizationGO:00300302840.135
regulation of nucleic acid templated transcriptionGO:19035062130.133
negative regulation of biological processGO:00485193040.133
nucleobase containing compound biosynthetic processGO:00346542050.131
regulation of nitrogen compound metabolic processGO:00511712510.129
positive regulation of cellular processGO:00485222010.129
neuron differentiationGO:00301823530.127
regulation of developmental processGO:00507932470.127
response to external stimulusGO:00096052640.121
regulation of signal transductionGO:00099662250.118
embryonic hemopoiesisGO:0035162530.116
generation of neuronsGO:00486993850.114
cognitionGO:005089010.112
regulation of transcription dna templatedGO:00063552130.111
homeostasis of number of cellsGO:0048872620.111
primitive hemopoiesisGO:0060215270.110
multicellular organism growthGO:003526440.109
blood vessel morphogenesisGO:00485142160.108
cellular response to molecule of bacterial originGO:007121930.104
response to chemicalGO:00422213200.104
hematopoietic progenitor cell differentiationGO:0002244230.099
regulation of rna biosynthetic processGO:20011412130.099
response to woundingGO:00096111160.099
defense responseGO:0006952470.098
nuclear importGO:005117030.098
negative regulation of sequestering of calcium ionGO:005128340.096
neuron developmentGO:00486662620.093
positive regulation of immune responseGO:0050778110.092
endosomal transportGO:001619720.092
cellular response to lipopolysaccharideGO:007122230.092
regulation of cellular metabolic processGO:00313233200.092
aromatic compound biosynthetic processGO:00194382170.087
protein metabolic processGO:00195381830.087
positive regulation of cellular catabolic processGO:003133130.087
cell surface receptor signaling pathwayGO:00071663250.087
maintenance of locationGO:005123540.086
regulation of response to stimulusGO:00485832690.085
somatic muscle developmentGO:000752540.084
positive regulation of biological processGO:00485182530.083
myeloid cell homeostasisGO:0002262560.077
embryonic organ developmentGO:00485683810.077
localization of cellGO:00516742440.077
regulation of production of molecular mediator of immune responseGO:000270010.077
positive regulation of response to stimulusGO:0048584800.077
regulation of multicellular organismal processGO:00512392770.076
stem cell proliferationGO:007208940.076
positive regulation of multicellular organismal processGO:0051240520.075
heart developmentGO:00075073130.072
regulation of cell matrix adhesionGO:000195210.072
b cell activationGO:004211320.071
negative regulation of cellular processGO:00485232830.068
regulation of inflammatory responseGO:005072720.068
positive regulation of immune effector processGO:000269930.068
positive regulation of catabolic processGO:000989640.068
rna biosynthetic processGO:00327741810.066
cell part morphogenesisGO:00329902460.066
regulation of cellular macromolecule biosynthetic processGO:20001122220.065
cell morphogenesisGO:00009022890.065
positive regulation of transportGO:005105020.064
muscle structure developmentGO:00610611960.064
chemotaxisGO:00069351040.062
positive regulation of map kinase activityGO:004340630.062
t cell differentiation in thymusGO:003307760.062
vasculature developmentGO:00019442780.061
regulation of signalingGO:00230512350.060
positive regulation of cytokine productionGO:000181920.060
i kappab kinase nf kappab signalingGO:000724940.058
cellular response to organic substanceGO:00713101050.057
positive regulation of cytosolic calcium ion concentrationGO:000720440.056
cell motilityGO:00488702440.055
pattern recognition receptor signaling pathwayGO:000222150.055
regulation of innate immune responseGO:0045088110.055
regulation of molecular functionGO:0065009700.054
agingGO:000756820.054
single organism biosynthetic processGO:0044711710.053
stem cell differentiationGO:00488631170.053
positive regulation of cell activationGO:005086710.053
cell migrationGO:00164772370.053
cellular response to biotic stimulusGO:007121630.052
sequestering of calcium ionGO:005120830.052
cell cycle g1 s phase transitionGO:004484310.052
dorsal ventral pattern formationGO:00099531250.051
gamete generationGO:0007276330.051
convergent extension involved in gastrulationGO:0060027710.049
regulation of biosynthetic processGO:00098892500.049
organonitrogen compound metabolic processGO:1901564740.049
cellular response to external stimulusGO:007149620.049
cell deathGO:00082191210.049
Rat
biological adhesionGO:0022610400.049
single organism metabolic processGO:00447102170.048
programmed cell deathGO:00125011190.048
Rat
chordate embryonic developmentGO:00430092710.048
positive regulation of cellular component biogenesisGO:004408930.048
cellular response to extracellular stimulusGO:003166820.048
guanosine containing compound metabolic processGO:190106840.047
regulation of immune system processGO:0002682340.047
mitochondrion organizationGO:000700540.046
response to other organismGO:0051707970.046
axon developmentGO:00615641660.046
positive regulation of immune system processGO:0002684170.045
g1 s transition of mitotic cell cycleGO:000008210.045
regionalizationGO:00030022740.045
regulation of metabolic processGO:00192223590.045
neuron projection developmentGO:00311751800.045
deathGO:00162651210.044
Rat
lipid storageGO:001991510.044
gland developmentGO:00487321430.043
proteolysis involved in cellular protein catabolic processGO:005160330.043
immune responseGO:0006955280.042
negative regulation of protein transportGO:005122430.042
cell morphogenesis involved in differentiationGO:00009041950.042
regulation of cell shapeGO:000836010.042
calcium ion transport into cytosolGO:006040230.041
positive regulation of signalingGO:0023056560.040
cellular component assembly involved in morphogenesisGO:00109271070.040
positive regulation of response to external stimulusGO:003210390.040
response to ketoneGO:190165410.040
axonogenesisGO:00074091520.040
cellular protein catabolic processGO:004425740.040
regulation of response to cytokine stimulusGO:006075930.040
negative regulation of synapse assemblyGO:005196420.040
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.040
regulation of cellular biosynthetic processGO:00313262450.039
production of molecular mediator of immune responseGO:000244020.039
determination of left right symmetryGO:00073681790.039
negative regulation of myeloid cell differentiationGO:004563810.039
sensory organ developmentGO:00074233930.039
negative regulation of secretionGO:005104820.039
negative regulation of kinase activityGO:003367340.039
histone h3 k4 methylationGO:005156820.038
regulation of nucleotide catabolic processGO:003081120.038
cilium morphogenesisGO:0060271850.038
positive regulation of metabolic processGO:00098931080.038
neuron projection morphogenesisGO:00488121610.038
regulation of cell activationGO:005086510.038
negative regulation of macromolecule metabolic processGO:0010605760.038
negative regulation of cell communicationGO:0010648960.038
regulation of cytokine mediated signaling pathwayGO:000195930.038
spermatid differentiationGO:004851520.037
regulation of synaptic growth at neuromuscular junctionGO:000858210.037
bmp signaling pathwayGO:0030509520.037
leukocyte activationGO:0045321120.037
cellular response to nutrient levelsGO:003166920.037
specification of symmetryGO:00097992040.036
response to bacteriumGO:0009617580.036
morphogenesis of an epitheliumGO:00020093330.036
regulation of response to biotic stimulusGO:000283120.036
wnt signaling pathwayGO:0016055800.036
somite developmentGO:0061053960.036
positive regulation of apoptotic signaling pathwayGO:200123510.035
negative regulation of cellular component organizationGO:0051129160.035
regulation of cellular component organizationGO:0051128860.035
regulation of protein modification by small protein conjugation or removalGO:190332030.035
regulation of multicellular organism growthGO:004001440.035
tissue remodelingGO:004877140.035
positive regulation of gtpase activityGO:004354710.034
modification dependent macromolecule catabolic processGO:004363230.034
fin morphogenesisGO:0033334530.034
larval developmentGO:000216420.034
regulation of nervous system developmentGO:0051960900.033
release of sequestered calcium ion into cytosolGO:005120930.032
cellular amine metabolic processGO:004410620.032
regulation of cell differentiationGO:00455951420.032
regulation of establishment of protein localizationGO:007020140.032
cell projection morphogenesisGO:00488582440.032
positive regulation of purine nucleotide catabolic processGO:003312310.032
response to oxygen containing compoundGO:1901700550.032
brain morphogenesisGO:0048854180.032
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.032
cytokinesisGO:000091030.032
regulation of gtp catabolic processGO:003312420.031
regulation of protein ubiquitinationGO:003139630.031
establishment of localizationGO:00512342440.031
sequestering of metal ionGO:005123830.031
calcium ion homeostasisGO:0055074190.031
cellular component assemblyGO:00226071700.031
cellular cation homeostasisGO:0030003170.031
regulation of anatomical structure morphogenesisGO:00226031300.031
negative regulation of biosynthetic processGO:0009890550.031
regulation of protein bindingGO:004339330.030
lymphocyte differentiationGO:003009890.030
regulation of cytokine biosynthetic processGO:004203510.030
regulation of cell deathGO:00109411030.030
antimicrobial humoral responseGO:001973020.030
multi organism processGO:00517041340.030
regulation of protein metabolic processGO:0051246560.030
embryo development ending in birth or egg hatchingGO:00097922710.030
activation of mapk activityGO:000018730.029
germ cell developmentGO:0007281220.029
negative regulation of protein kinase activityGO:000646940.029
small molecule metabolic processGO:0044281770.029
regulation of protein complex assemblyGO:004325430.029
positive regulation of nucleotide catabolic processGO:003081310.029
cytosolic calcium ion transportGO:006040130.029
determination of dorsal ventral asymmetryGO:0048262340.028
positive regulation of signal transductionGO:0009967560.028
regulation of response to external stimulusGO:0032101310.028
positive regulation of cell deathGO:0010942290.028
negative regulation of multicellular organismal processGO:0051241690.028
apoptotic processGO:00069151160.028
cellular protein metabolic processGO:00442671290.028
hematopoietic stem cell differentiationGO:0060218200.027
protein polymerizationGO:005125840.027
positive regulation of myeloid cell differentiationGO:004563920.027
immune effector processGO:0002252230.027
protein acylationGO:004354330.027
regulation of protein transportGO:005122330.027
macromolecule modificationGO:00434121110.027
system processGO:00030081850.027
regulation of erythrocyte differentiationGO:004564620.027
cell matrix adhesionGO:000716040.027
positive regulation of cell cycleGO:004578730.027
mononuclear cell proliferationGO:003294310.027
response to organic substanceGO:00100331530.027
stem cell developmentGO:0048864820.027
epithelial cell developmentGO:0002064420.027
mitochondrial transportGO:000683920.027
positive regulation of production of molecular mediator of immune responseGO:000270210.027
protein modification processGO:00362111000.027
positive regulation of protein complex assemblyGO:003133420.026
regulation of catalytic activityGO:0050790550.026
digestive system developmentGO:00551232890.026
macrophage differentiationGO:003022570.026
cellular component movementGO:00069283350.026
regulation of neuron differentiationGO:0045664560.026
b cell mediated immunityGO:001972430.026
synaptic growth at neuromuscular junctionGO:005112420.025
protein secretionGO:000930610.025
cellular divalent inorganic cation homeostasisGO:0072503130.025
actin filament polymerizationGO:003004120.025
response to virusGO:0009615210.025
regulation of cellular amino acid metabolic processGO:000652100.025
macroautophagyGO:001623610.025
lymphocyte proliferationGO:004665110.025
mrna metabolic processGO:0016071200.025
cell adhesionGO:0007155400.025
response to axon injuryGO:0048678140.025
central nervous system neuron differentiationGO:0021953740.025
phagocytosis engulfmentGO:000691110.025
negative regulation of protein phosphorylationGO:000193340.024
phagocytosisGO:000690930.024
negative regulation of cytoplasmic transportGO:190365020.024
negative regulation of metabolic processGO:0009892860.024
autophagyGO:000691440.024
regulation of cellular protein metabolic processGO:0032268520.024
regulation of cell substrate adhesionGO:001081010.024
leukocyte proliferationGO:007066110.024
homeostasis of number of cells within a tissueGO:004887340.024
regenerationGO:0031099910.024
negative regulation of secretion by cellGO:190353120.024
anterior posterior pattern specificationGO:00099521520.024
regulation of cellular amine metabolic processGO:003323800.024
immunoglobulin mediated immune responseGO:001606430.024
symbiosis encompassing mutualism through parasitismGO:004440340.024
innate immune responseGO:0045087130.023
muscle organ developmentGO:00075171010.023
gtp catabolic processGO:000618420.023
regulation of cell developmentGO:00602841000.023
amine metabolic processGO:000930820.023
modification dependent protein catabolic processGO:001994130.023
negative regulation of protein localization to nucleusGO:190018120.023
humoral immune response mediated by circulating immunoglobulinGO:000245530.023
negative regulation of mitosisGO:004583930.023
optic placode formation involved in camera type eye formationGO:004661930.022
cellular amino acid metabolic processGO:000652070.022
negative regulation of signalingGO:0023057960.022
skin developmentGO:0043588540.022
regulation of synapse organizationGO:005080730.022
regulation of stem cell proliferationGO:007209120.022
membrane invaginationGO:001032410.022
regulation of cell proliferationGO:0042127370.022
positive regulation of protein metabolic processGO:0051247230.022
cellular ketone metabolic processGO:0042180110.021
intracellular signal transductionGO:0035556850.021
regulation of sequestering of calcium ionGO:005128240.021
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.021
chemical homeostasisGO:0048878490.021
tissue homeostasisGO:0001894250.021
metal ion homeostasisGO:0055065260.021
regulation of cytoplasmic transportGO:190364940.021
positive regulation of molecular functionGO:0044093330.021
regulation of purine nucleotide catabolic processGO:003312120.021
gtp metabolic processGO:004603940.021
regulation of cytokine productionGO:000181730.021
nuclear transportGO:005116940.021
proteolysisGO:0006508380.021
osteoclast differentiationGO:003031610.020
proteasomal protein catabolic processGO:001049820.020
spermatid developmentGO:000728620.020
positive regulation of leukocyte differentiationGO:190210710.020
regulation of bindingGO:005109830.020
positive regulation of cellular metabolic processGO:0031325940.020
peptidyl serine phosphorylationGO:001810510.020
negative regulation of signal transductionGO:0009968940.020
multicellular organismal reproductive processGO:0048609350.020
positive regulation of multi organism processGO:004390230.020
neuron neuron synaptic transmissionGO:000727010.020
cell substrate adhesionGO:003158940.020
organelle fusionGO:004828430.020
positive regulation of gtp catabolic processGO:003312610.019
developmental growthGO:00485891660.019
regulation of myeloid cell differentiationGO:004563780.019
cellular amide metabolic processGO:004360340.019
monocyte differentiationGO:003022420.019
regulation of immune responseGO:0050776140.019
kupffer s vesicle developmentGO:0070121500.019
tube morphogenesisGO:00352393490.019
pericardium developmentGO:006003910.019
segmentationGO:0035282970.019
negative regulation of defense responseGO:003134820.019
response to molecule of bacterial originGO:0002237140.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
cellular response to lipidGO:0071396390.019
phosphate containing compound metabolic processGO:00067961080.019
negative regulation of developmental processGO:0051093650.018
negative regulation of myeloid leukocyte differentiationGO:000276210.018
regulation of nucleoside metabolic processGO:000911820.018
gastrulationGO:00073692080.018
cell migration involved in gastrulationGO:0042074790.018
growthGO:00400071740.018
regulation of neurological system processGO:003164420.018
dorsal aorta developmentGO:003590740.018
stem cell maintenanceGO:001982740.018
single organism nuclear importGO:190259330.018
viral processGO:001603210.018
sensory perception of chemical stimulusGO:000760630.018
protein targeting to nucleusGO:004474430.018
neuron projection guidanceGO:0097485860.018
regulation of protein localization to plasma membraneGO:190307610.018
regulation of gtpase activityGO:004308720.018
response to lipidGO:0033993600.017
negative regulation of nuclear divisionGO:005178430.017
regulation of epithelial cell proliferationGO:005067830.017
positive regulation of nucleoside metabolic processGO:004597910.017
mitotic cytokinesisGO:000028130.017
negative regulation of cellular metabolic processGO:0031324770.017
taxisGO:00423301090.017
cellular response to starvationGO:000926710.017
regulation of vasculature developmentGO:1901342330.017
cell proliferationGO:0008283800.017
lipid metabolic processGO:0006629520.017
protein localization to nucleusGO:003450430.017
ameboidal type cell migrationGO:00016671430.017
cellular response to oxygen containing compoundGO:1901701200.017
erythrocyte maturationGO:004324980.017
cytoskeleton dependent cytokinesisGO:006164030.017
t cell activationGO:004211060.017
establishment of protein localization to organelleGO:007259440.017
phosphatidylinositol 3 kinase signalingGO:001406520.016
single organism behaviorGO:0044708240.016
myeloid cell developmentGO:0061515320.016
transportGO:00068102200.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
regulation of membrane potentialGO:0042391230.016
regulation of cellular ketone metabolic processGO:001056570.016
lateral inhibitionGO:004633110.016
stem cell divisionGO:001714510.016
positive regulation of cell communicationGO:0010647560.016
protein importGO:001703830.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
neuron remodelingGO:001632210.016
positive regulation of jnk cascadeGO:004633030.016
positive regulation of cytokine biosynthetic processGO:004210810.016
somitogenesisGO:0001756870.016
skeletal muscle organ developmentGO:0060538780.016
natural killer cell mediated immunityGO:000222810.016
cellular component biogenesisGO:00440851780.016
regulation of cell motilityGO:2000145460.016
muscle cell differentiationGO:00426921390.016
heme metabolic processGO:004216890.016
regulation of neuron projection developmentGO:0010975400.016
developmental programmed cell deathGO:001062340.016
extrinsic apoptotic signaling pathwayGO:009719130.015
multicellular organism reproductionGO:0032504350.015
organelle organizationGO:00069962270.015
heart valve formationGO:000318840.015
interspecies interaction between organismsGO:004441940.015
humoral immune responseGO:000695950.015
transition metal ion transportGO:000004160.015
negative regulation of ras protein signal transductionGO:004658010.015
negative regulation of response to stimulusGO:00485851040.015
negative regulation of cell differentiationGO:0045596460.015
negative regulation of gene expressionGO:0010629650.015
negative regulation of catalytic activityGO:0043086210.015
axon guidanceGO:0007411860.015
somatic stem cell maintenanceGO:003501910.015
regulation of blood vessel sizeGO:005088020.015
organonitrogen compound biosynthetic processGO:1901566470.015
regulation of cellular component movementGO:0051270550.014
regulation of rho protein signal transductionGO:003502320.014
positive regulation of cellular biosynthetic processGO:0031328680.014
reflexGO:006000420.014
regulation of mitochondrion organizationGO:001082110.014
regulation of neurogenesisGO:0050767870.014
establishment of endothelial barrierGO:006102830.014
regulation of leukocyte differentiationGO:190210550.014
aorta developmentGO:003590440.014
negative regulation of macromolecule biosynthetic processGO:0010558480.014
odontogenesis of dentin containing toothGO:004247510.014
positive regulation of developmental processGO:0051094500.014
regulation of programmed cell deathGO:00430671010.014
fin regenerationGO:0031101510.014
regulation of tube sizeGO:003515020.014
epithelial cell morphogenesisGO:000338220.014
protein polyubiquitinationGO:000020940.014
transcription from rna polymerase ii promoterGO:0006366800.013
cellular process involved in reproduction in multicellular organismGO:0022412280.013
defense response to other organismGO:0098542330.013
regulation of protein polymerizationGO:003227120.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
phosphatidylinositol mediated signalingGO:004801520.013
cytokine metabolic processGO:004210710.013
positive regulation of inflammatory responseGO:005072910.013
cell activationGO:0001775160.013
mesenchymal cell differentiationGO:0048762870.013
regulation of cellular component sizeGO:0032535300.013
single organism organelle organizationGO:19025891990.013

pdcd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
aplastic anemiaDOID:1244900.029
bone marrow diseaseDOID:496100.029
anemiaDOID:235500.029
disease of anatomical entityDOID:700.029
immune system diseaseDOID:291400.029
hematopoietic system diseaseDOID:7400.029
disease of cellular proliferationDOID:1456600.028
cancerDOID:16200.028
organ system cancerDOID:005068600.026
gastrointestinal system cancerDOID:311900.019
colorectal cancerDOID:925600.019
colon cancerDOID:21900.019
colon carcinomaDOID:152000.019
large intestine cancerDOID:567200.019
intestinal cancerDOID:1015500.019