Danio rerio

0 known processes

akr1b1

aldo-keto reductase family 1, member B1 (aldose reductase)

(Aliases: zgc:86611)

akr1b1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.057
positive regulation of cellular component biogenesisGO:004408930.053
multicellular organism growthGO:003526440.046
cytokinesisGO:000091030.045
positive regulation of transportGO:005105020.044
generation of neuronsGO:00486993850.042
agingGO:000756820.042
cell projection organizationGO:00300302840.042
autophagyGO:000691440.040
cellular component morphogenesisGO:00329893360.039
neuron differentiationGO:00301823530.039
signal transductionGO:00071654550.039
Rat
transportGO:00068102200.037
cognitionGO:005089010.036
amine metabolic processGO:000930820.036
adult behaviorGO:003053420.036
regulation of biological qualityGO:00650082630.035
Rat
cell morphogenesisGO:00009022890.035
establishment of localizationGO:00512342440.034
regulation of establishment of protein localizationGO:007020140.034
cellular amine metabolic processGO:004410620.034
neuron developmentGO:00486662620.033
single organism localizationGO:19025782250.032
cell part morphogenesisGO:00329902460.031
regulation of synapse organizationGO:005080730.031
regulation of multicellular organism growthGO:004001440.031
guanosine containing compound catabolic processGO:190106920.031
regulation of protein transportGO:005122330.030
regulation of synaptic growth at neuromuscular junctionGO:000858210.030
embryonic organ developmentGO:00485683810.030
single organism transportGO:00447652060.030
gtp metabolic processGO:004603940.029
protein localization to nucleusGO:003450430.029
single organism metabolic processGO:00447102170.029
Human Rat
heart developmentGO:00075073130.028
regulation of metal ion transportGO:001095940.028
meiotic nuclear divisionGO:000712640.028
establishment of protein localization to organelleGO:007259440.028
morphogenesis of an epitheliumGO:00020093330.028
organelle organizationGO:00069962270.028
single organism organelle organizationGO:19025891990.028
phagocytosisGO:000690930.027
cilium assemblyGO:0042384580.027
synaptic growth at neuromuscular junctionGO:005112420.027
microtubule organizing center organizationGO:003102310.027
maintenance of locationGO:005123540.027
stem cell proliferationGO:007208940.027
positive regulation of cell cycleGO:004578730.027
golgi vesicle transportGO:004819330.027
gtp catabolic processGO:000618420.027
nuclear transportGO:005116940.026
cellular response to extracellular stimulusGO:003166820.026
guanosine containing compound metabolic processGO:190106840.026
cell projection morphogenesisGO:00488582440.026
regulation of developmental processGO:00507932470.025
regulation of protein complex assemblyGO:004325430.025
cellular component biogenesisGO:00440851780.025
regulation of cell communicationGO:00106462320.025
Rat
establishment of protein localization to plasma membraneGO:009000210.025
cellular component movementGO:00069283350.025
regulation of cell shapeGO:000836010.025
cellular response to nutrient levelsGO:003166920.025
regulation of metabolic processGO:00192223590.025
organelle fusionGO:004828430.024
nucleocytoplasmic transportGO:000691340.024
endosomal transportGO:001619720.024
organic cyclic compound metabolic processGO:19013603010.024
Rat
embryonic organ morphogenesisGO:00485622740.024
cilium morphogenesisGO:0060271850.024
regulation of synapse assemblyGO:005196330.024
rna metabolic processGO:00160702190.024
regulation of intracellular protein transportGO:003315730.023
digestive system developmentGO:00551232890.023
positive regulation of catabolic processGO:000989640.023
membrane fusionGO:006102520.023
regulation of autophagyGO:001050630.023
neuroblast proliferationGO:000740520.023
cellular nitrogen compound metabolic processGO:00346412900.023
response to chemicalGO:00422213200.023
Rat
negative regulation of kinase activityGO:003367340.023
extrinsic apoptotic signaling pathwayGO:009719130.023
cellular response to external stimulusGO:007149620.022
regulation of protein targetingGO:190353320.022
regulation of cytoplasmic transportGO:190364940.022
regulation of protein localization to nucleusGO:190018020.022
neuron projection developmentGO:00311751800.022
negative regulation of protein phosphorylationGO:000193340.022
centrosome organizationGO:005129710.022
locomotionGO:00400113130.022
regulation of cellular amine metabolic processGO:003323800.022
regulation of signal transductionGO:00099662250.022
Rat
protein targeting to nucleusGO:004474430.021
chordate embryonic developmentGO:00430092710.021
positive regulation of cellular catabolic processGO:003133130.021
oxoacid metabolic processGO:0043436310.021
response to carbohydrateGO:000974330.021
response to drugGO:004249330.021
carboxylic acid metabolic processGO:0019752220.021
alcohol biosynthetic processGO:004616520.021
Rat
neurotransmitter transportGO:000683620.020
negative regulation of protein kinase activityGO:000646940.020
regulation of nucleoside metabolic processGO:000911820.020
homeostatic processGO:00425921420.020
Rat
regulation of synaptic plasticityGO:004816710.020
meiotic cell cycle processGO:190304630.020
organonitrogen compound metabolic processGO:1901564740.020
Rat
small molecule metabolic processGO:0044281770.020
Human Rat
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.020
nuclear importGO:005117030.020
regulation of cellular amino acid metabolic processGO:000652100.019
nitrogen compound metabolic processGO:00068073190.019
Human Rat
neuron projection morphogenesisGO:00488121610.019
regulation of multicellular organismal processGO:00512392770.019
regulation of nucleotide catabolic processGO:003081120.019
positive regulation of biological processGO:00485182530.019
Rat
cellular response to starvationGO:000926710.019
brain developmentGO:00074202930.019
Fly
single fertilizationGO:000733830.019
regulation of signalingGO:00230512350.019
Rat
exocytosisGO:000688710.019
amino acid transportGO:000686520.019
organic acid metabolic processGO:0006082310.019
ribonucleoside monophosphate catabolic processGO:000915840.019
tube morphogenesisGO:00352393490.019
ion transportGO:00068111140.019
cellular ketone metabolic processGO:0042180110.019
Human
negative regulation of biological processGO:00485193040.019
regulation of cellular metabolic processGO:00313233200.019
cellular carbohydrate metabolic processGO:004426240.019
Rat
cellular component assemblyGO:00226071700.018
regulation of cytokine productionGO:000181730.018
cell substrate adhesionGO:003158940.018
response to external stimulusGO:00096052640.018
regulation of cellular ketone metabolic processGO:001056570.018
digestive tract morphogenesisGO:00485462310.018
cellular component disassemblyGO:002241110.018
positive regulation of secretion by cellGO:190353210.018
regulation of cell activationGO:005086510.018
regulation of purine nucleotide catabolic processGO:003312120.018
cellular localizationGO:0051641970.018
regulation of cell substrate adhesionGO:001081010.018
protein import into nucleusGO:000660630.018
positive regulation of secretionGO:005104710.018
regulation of primary metabolic processGO:00800903110.018
single organism nuclear importGO:190259330.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
central nervous system developmentGO:00074173870.018
Fly
cellular biosynthetic processGO:00442492860.018
Rat
regulation of gene expressionGO:00104682650.017
mitochondrion organizationGO:000700540.017
positive regulation of protein complex assemblyGO:003133420.017
transmembrane transportGO:00550851200.017
regulation of bindingGO:005109830.017
gene expressionGO:00104672520.017
protein complex disassemblyGO:004324110.017
regulation of protein catabolic processGO:004217610.017
cytoskeleton dependent cytokinesisGO:006164030.017
atp catabolic processGO:000620040.017
cellular component assembly involved in morphogenesisGO:00109271070.017
cellular macromolecule metabolic processGO:00442603910.017
organelle assemblyGO:00709251100.017
cell migrationGO:00164772370.017
regulation of macromolecule metabolic processGO:00602553170.017
positive regulation of gtpase activityGO:004354710.017
establishment of synaptic vesicle localizationGO:009748010.017
regulation of gtp catabolic processGO:003312420.017
system processGO:00030081850.017
tube closureGO:006060610.017
eye developmentGO:00016542770.017
protein importGO:001703830.017
cell morphogenesis involved in differentiationGO:00009041950.017
er to golgi vesicle mediated transportGO:000688810.016
response to nutrientGO:000758430.016
regulation of reproductive processGO:200024140.016
regulation of nucleocytoplasmic transportGO:004682220.016
response to stressGO:00069502630.016
Rat
regulation of gtpase activityGO:004308720.016
cell motilityGO:00488702440.016
regulation of response to stimulusGO:00485832690.016
Rat
regulation of sequestering of calcium ionGO:005128240.016
actin polymerization or depolymerizationGO:000815420.016
phosphorus metabolic processGO:00067931090.016
synaptic vesicle localizationGO:009747910.016
lipid storageGO:001991510.016
response to monosaccharideGO:003428430.016
lateral inhibitionGO:004633110.016
nucleobase containing compound metabolic processGO:00061392740.016
head developmentGO:00603223030.016
Fly
developmental growthGO:00485891660.016
positive regulation of cytoskeleton organizationGO:005149530.016
cellular amino acid metabolic processGO:000652070.015
positive regulation of cellular amine metabolic processGO:003324000.015
somatic muscle developmentGO:000752540.015
neuron neuron synaptic transmissionGO:000727010.015
sequestering of metal ionGO:005123830.015
cilium organizationGO:0044782710.015
single organism membrane fusionGO:004480120.015
purine nucleoside monophosphate catabolic processGO:000912840.015
sensory organ developmentGO:00074233930.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
response to hexoseGO:000974630.015
negative regulation of cellular processGO:00485232830.015
cell surface receptor signaling pathwayGO:00071663250.015
forebrain cell migrationGO:002188510.015
regulation of cellular component organizationGO:0051128860.015
organic substance biosynthetic processGO:19015762890.015
Rat
macroautophagyGO:001623610.015
rna localizationGO:000640340.015
regulation of neural precursor cell proliferationGO:200017730.015
negative regulation of intracellular transportGO:003238730.015
response to glucoseGO:000974930.015
establishment of localization in cellGO:0051649770.015
organic substance transportGO:0071702580.015
positive regulation of nucleoside metabolic processGO:004597910.015
positive regulation of synapse assemblyGO:005196510.015
membrane lipid biosynthetic processGO:004646720.014
localization of cellGO:00516742440.014
macromolecular complex disassemblyGO:003298410.014
protein localization to plasma membraneGO:007265910.014
negative regulation of cytoplasmic transportGO:190365020.014
positive regulation of nucleotide catabolic processGO:003081310.014
digestive tract developmentGO:00485652650.014
growthGO:00400071740.014
regulation of multicellular organismal developmentGO:20000262230.014
spermatid developmentGO:000728620.014
skeletal system developmentGO:00015011810.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
protein polymerizationGO:005125840.014
centrosome cycleGO:000709810.014
regulation of ion transmembrane transporter activityGO:003241220.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
microtubule based movementGO:0007018330.014
regulation of nitrogen compound metabolic processGO:00511712510.014
fertilizationGO:000956630.014
carbohydrate homeostasisGO:003350010.014
specification of symmetryGO:00097992040.014
glucose homeostasisGO:004259310.014
protein heterooligomerizationGO:005129110.014
regulation of neurotransmitter transportGO:005158810.014
regulation of epithelial cell proliferationGO:005067830.014
cellular aromatic compound metabolic processGO:00067252950.014
Rat
neurotransmitter secretionGO:000726920.014
heterocycle metabolic processGO:00464832900.014
primary neural tube formationGO:001402010.014
gastrulationGO:00073692080.014
symbiosis encompassing mutualism through parasitismGO:004440340.014
compound eye developmentGO:004874920.014
carbohydrate biosynthetic processGO:001605110.013
Rat
mitochondrial transportGO:000683920.013
cellular amide metabolic processGO:004360340.013
female sex differentiationGO:004666040.013
negative regulation of sequestering of calcium ionGO:005128340.013
stem cell maintenanceGO:001982740.013
g1 s transition of mitotic cell cycleGO:000008210.013
secondary metabolic processGO:001974830.013
Human
regulation of protein polymerizationGO:003227120.013
cation transportGO:0006812810.013
protein metabolic processGO:00195381830.013
regulation of transmembrane transporter activityGO:002289820.013
phagocytosis engulfmentGO:000691110.013
embryo development ending in birth or egg hatchingGO:00097922710.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
regulation of biosynthetic processGO:00098892500.013
cytosolic calcium ion transportGO:006040130.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
axon developmentGO:00615641660.013
synaptic vesicle transportGO:004848910.013
chemosensory behaviorGO:000763510.013
protein secretionGO:000930610.013
i kappab kinase nf kappab signalingGO:000724940.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
cellular response to radiationGO:007147840.013
response to abiotic stimulusGO:00096281220.013
Rat
cell projection assemblyGO:0030031640.013
regionalizationGO:00030022740.013
regulation of dendrite developmentGO:005077330.012
axonogenesisGO:00074091520.012
protein dephosphorylationGO:000647030.012
cortical cytoskeleton organizationGO:003086510.012
membrane invaginationGO:001032410.012
nucleobase containing compound biosynthetic processGO:00346542050.012
adherens junction organizationGO:003433240.012
phosphate containing compound metabolic processGO:00067961080.012
regulation of cell projection assemblyGO:006049140.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
regulation of transporter activityGO:003240920.012
intracellular mrna localizationGO:000829810.012
peptide transportGO:001583310.012
cellular macromolecule biosynthetic processGO:00346452240.012
cellular transition metal ion homeostasisGO:004691630.012
positive regulation of gtp catabolic processGO:003312610.012
macromolecule biosynthetic processGO:00090592270.012
regulation of neurogenesisGO:0050767870.012
convergent extensionGO:00600261180.012
actin filament polymerizationGO:003004120.012
regulation of cell developmentGO:00602841000.012
regulation of mrna processingGO:005068430.012
determination of left right symmetryGO:00073681790.012
actin filament based movementGO:003004810.012
blood vessel developmentGO:00015682460.012
leukocyte proliferationGO:007066110.012
protein homooligomerizationGO:005126030.012
organelle localizationGO:0051640490.012
regulation of erk1 and erk2 cascadeGO:007037240.012
positive regulation of exocytosisGO:004592110.012
cellular response to chemical stimulusGO:00708871570.011
Rat
cytoplasm organizationGO:000702840.011
macromolecule modificationGO:00434121110.011
regulation of cellular biosynthetic processGO:00313262450.011
regulation of calcium ion transportGO:005192420.011
dicarboxylic acid transportGO:000683510.011
nucleic acid metabolic processGO:00903042440.011
ubiquitin dependent protein catabolic processGO:000651130.011
camera type eye developmentGO:00430102220.011
determination of bilateral symmetryGO:00098552040.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
regulation of nervous system developmentGO:0051960900.011
sequestering of calcium ionGO:005120830.011
peptidyl serine phosphorylationGO:001810510.011
negative regulation of catabolic processGO:000989530.011
startle responseGO:000196440.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
spermatid differentiationGO:004851520.011
immune system processGO:00023762410.011
melanosome transportGO:0032402190.011
post golgi vesicle mediated transportGO:000689210.011
regulation of macromolecule biosynthetic processGO:00105562250.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
regulation of exocytosisGO:001715710.011
vasculature developmentGO:00019442780.011
positive regulation of cellular processGO:00485222010.011
Rat
modification dependent macromolecule catabolic processGO:004363230.011
response to vitaminGO:003327330.011
ion transmembrane transportGO:0034220910.011
regulation of anatomical structure morphogenesisGO:00226031300.011
organic cyclic compound biosynthetic processGO:19013622230.011
golgi organizationGO:000703010.011
cellular biogenic amine metabolic processGO:000657620.011
neurological system processGO:0050877620.011
mitotic cytokinesisGO:000028130.011
nucleic acid transportGO:005065720.011
regulation of protein complex disassemblyGO:004324410.011
ameboidal type cell migrationGO:00016671430.011
negative regulation of defense responseGO:003134820.011
response to corticosteroidGO:003196010.011
release of sequestered calcium ion into cytosolGO:005120930.011
developmental programmed cell deathGO:001062340.011
cell matrix adhesionGO:000716040.011
regulation of inflammatory responseGO:005072720.011
nucleic acid templated transcriptionGO:00976591810.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
stem cell divisionGO:001714510.011
erk1 and erk2 cascadeGO:007037140.011
cellular protein metabolic processGO:00442671290.011
oocyte anterior posterior axis specificationGO:000731440.010
multicellular organismal response to stressGO:003355520.010
cation transmembrane transportGO:0098655650.010
positive regulation of cell adhesionGO:004578510.010
negative regulation of secretionGO:005104820.010
regulation of meiotic cell cycleGO:005144510.010
regulation of stem cell proliferationGO:007209120.010
protein targeting to membraneGO:000661210.010
regulation of protein modification by small protein conjugation or removalGO:190332030.010
positive regulation of cell divisionGO:005178120.010
cell substrate junction assemblyGO:000704420.010
neuromuscular process controlling balanceGO:005088530.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
nucleobase containing compound transportGO:001593120.010
regulation of tube sizeGO:003515020.010
pigmentationGO:0043473850.010
transcription from rna polymerase ii promoterGO:0006366800.010
negative regulation of multi organism processGO:004390130.010
meiotic chromosome segregationGO:004513230.010
peptidyl serine modificationGO:001820920.010
negative regulation of mapk cascadeGO:004340940.010
macromolecular complex subunit organizationGO:0043933740.010
ovulation cycle processGO:002260220.010

akr1b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.062
nervous system diseaseDOID:86300.026
musculoskeletal system diseaseDOID:1700.022
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.017
muscle tissue diseaseDOID:6600.013
muscular diseaseDOID:008000000.013
myopathyDOID:42300.013
sensory system diseaseDOID:005015500.011
cardiovascular system diseaseDOID:128700.011