Danio rerio

32 known processes

flii

flightless I homolog (Drosophila)

(Aliases: im:7141769)

flii biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.392
cellular macromolecule metabolic processGO:00442603910.254
ubiquitin dependent protein catabolic processGO:000651130.253
modification dependent macromolecule catabolic processGO:004363230.239
regulation of metabolic processGO:00192223590.234
cellular protein catabolic processGO:004425740.231
modification dependent protein catabolic processGO:001994130.224
proteolysis involved in cellular protein catabolic processGO:005160330.221
regulation of biological qualityGO:00650082630.215
cytoskeleton organizationGO:0007010960.195
proteasomal protein catabolic processGO:001049820.180
vasculature developmentGO:00019442780.178
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.176
cortical actin cytoskeleton organizationGO:003086610.171
response to chemicalGO:00422213200.165
cellular component morphogenesisGO:00329893360.146
establishment of localizationGO:00512342440.140
cell surface receptor signaling pathwayGO:00071663250.134
signal transductionGO:00071654550.130
embryo development ending in birth or egg hatchingGO:00097922710.130
regulation of cellular metabolic processGO:00313233200.127
organelle organizationGO:00069962270.118
agingGO:000756820.112
blood vessel developmentGO:00015682460.111
cellular nitrogen compound metabolic processGO:00346412900.111
nucleocytoplasmic transportGO:000691340.110
single organism localizationGO:19025782250.110
response to external stimulusGO:00096052640.108
single organism organelle organizationGO:19025891990.105
actin filament based processGO:0030029640.105
cell projection organizationGO:00300302840.102
cellular component movementGO:00069283350.100
cortical cytoskeleton organizationGO:003086510.097
cellular protein metabolic processGO:00442671290.094
nuclear transportGO:005116940.092
generation of neuronsGO:00486993850.088
stem cell proliferationGO:007208940.088
nucleic acid metabolic processGO:00903042440.088
regulation of cell developmentGO:00602841000.085
regulation of cell deathGO:00109411030.085
response to organic substanceGO:00100331530.084
peptidyl serine phosphorylationGO:001810510.083
cell migrationGO:00164772370.081
regulation of primary metabolic processGO:00800903110.079
positive regulation of cellular catabolic processGO:003133130.078
negative regulation of cellular processGO:00485232830.078
negative regulation of protein phosphorylationGO:000193340.077
neuron differentiationGO:00301823530.076
protein metabolic processGO:00195381830.076
regulation of establishment of protein localizationGO:007020140.076
cellular protein modification processGO:00064641000.076
cellular component assemblyGO:00226071700.075
regulation of cellular macromolecule biosynthetic processGO:20001122220.074
regulation of cell communicationGO:00106462320.074
peptidyl serine modificationGO:001820920.074
tube morphogenesisGO:00352393490.074
regulation of signal transductionGO:00099662250.073
regulation of signalingGO:00230512350.073
cellular amine metabolic processGO:004410620.072
response to stressGO:00069502630.072
sensory organ developmentGO:00074233930.071
protein dephosphorylationGO:000647030.071
locomotionGO:00400113130.071
embryonic organ developmentGO:00485683810.070
phosphorus metabolic processGO:00067931090.069
cellular response to chemical stimulusGO:00708871570.068
organonitrogen compound metabolic processGO:1901564740.067
heart developmentGO:00075073130.067
programmed cell deathGO:00125011190.067
deathGO:00162651210.067
negative regulation of kinase activityGO:003367340.066
regulation of nitrogen compound metabolic processGO:00511712510.066
positive regulation of map kinase activityGO:004340630.064
regulation of macromolecule biosynthetic processGO:00105562250.063
muscle cell differentiationGO:00426921390.062
regulation of cellular amine metabolic processGO:003323800.062
organelle assemblyGO:00709251100.061
protein localization to nucleusGO:003450430.061
gene expressionGO:00104672520.061
actin cytoskeleton organizationGO:0030036630.061
blood vessel morphogenesisGO:00485142160.061
cell morphogenesisGO:00009022890.061
macromolecule biosynthetic processGO:00090592270.060
regulation of macromolecule metabolic processGO:00602553170.059
establishment of protein localization to organelleGO:007259440.057
extrinsic apoptotic signaling pathwayGO:009719130.057
regulation of cell shapeGO:000836010.057
macromolecule modificationGO:00434121110.056
amine metabolic processGO:000930820.056
apoptotic processGO:00069151160.056
cellular biosynthetic processGO:00442492860.056
heterocycle metabolic processGO:00464832900.056
intracellular signal transductionGO:0035556850.055
transportGO:00068102200.054
protein import into nucleusGO:000660630.054
regulation of protein transportGO:005122330.054
regulation of synaptic plasticityGO:004816710.054
positive regulation of cellular processGO:00485222010.054
rna metabolic processGO:00160702190.053
immune system processGO:00023762410.053
small molecule metabolic processGO:0044281770.053
maintenance of locationGO:005123540.053
phosphate containing compound metabolic processGO:00067961080.053
regulation of circadian rhythmGO:004275240.052
nuclear importGO:005117030.052
cellular ketone metabolic processGO:0042180110.052
cellular macromolecule biosynthetic processGO:00346452240.052
regulation of cellular amino acid metabolic processGO:000652100.051
regulation of response to stimulusGO:00485832690.051
regulation of multicellular organismal processGO:00512392770.051
multicellular organism growthGO:003526440.050
cell substrate adhesionGO:003158940.050
hematopoietic or lymphoid organ developmentGO:00485341910.050
aromatic compound biosynthetic processGO:00194382170.050
regulation of nucleobase containing compound metabolic processGO:00192192500.050
organic substance biosynthetic processGO:19015762890.050
pole plasm assemblyGO:000731540.050
single organism transportGO:00447652060.050
regulation of intracellular protein transportGO:003315730.049
response to abiotic stimulusGO:00096281220.049
central nervous system developmentGO:00074173870.049
regulation of cellular biosynthetic processGO:00313262450.048
regulation of extrinsic apoptotic signaling pathwayGO:200123630.048
cellular amino acid metabolic processGO:000652070.048
biosynthetic processGO:00090582940.048
regulation of cell projection assemblyGO:006049140.047
protein modification processGO:00362111000.047
positive regulation of catabolic processGO:000989640.046
protein polyubiquitinationGO:000020940.046
localization of cellGO:00516742440.045
regulation of multicellular organismal developmentGO:20000262230.045
establishment of protein localization to plasma membraneGO:009000210.045
cell motilityGO:00488702440.045
cognitionGO:005089010.045
embryonic organ morphogenesisGO:00485622740.045
positive regulation of biological processGO:00485182530.045
negative regulation of protein kinase activityGO:000646940.045
regulation of multicellular organism growthGO:004001440.044
lipid storageGO:001991510.044
regulation of programmed cell deathGO:00430671010.044
centrosome cycleGO:000709810.044
positive regulation of cell cycleGO:004578730.043
positive regulation of transportGO:005105020.043
protein targeting to nucleusGO:004474430.043
gtp metabolic processGO:004603940.043
cellular nitrogen compound biosynthetic processGO:00442712180.042
single organism metabolic processGO:00447102170.042
response to alkaloidGO:004327920.041
regulation of protein import into nucleusGO:004230620.041
angiogenesisGO:00015251580.041
single organism nuclear importGO:190259330.041
muscle structure developmentGO:00610611960.041
regulation of biosynthetic processGO:00098892500.040
heterocycle biosynthetic processGO:00181302150.040
neuron developmentGO:00486662620.040
oocyte anterior posterior axis specificationGO:000731440.040
system processGO:00030081850.040
regulation of cytokine productionGO:000181730.040
phagocytosisGO:000690930.040
nitrogen compound metabolic processGO:00068073190.040
rna localizationGO:000640340.040
regulation of cytoplasmic transportGO:190364940.039
negative regulation of biological processGO:00485193040.039
organic acid metabolic processGO:0006082310.039
morphogenesis of an epitheliumGO:00020093330.039
regulation of developmental processGO:00507932470.039
cellular catabolic processGO:0044248270.038
response to radiationGO:0009314510.038
regulation of protein modification by small protein conjugation or removalGO:190332030.037
regulation of rna metabolic processGO:00512522240.037
somite developmentGO:0061053960.037
cell morphogenesis involved in differentiationGO:00009041950.037
organic cyclic compound metabolic processGO:19013603010.037
meiotic nuclear divisionGO:000712640.036
positive regulation of purine nucleotide catabolic processGO:003312310.036
guanosine containing compound metabolic processGO:190106840.036
positive regulation of cellular metabolic processGO:0031325940.036
muscle tissue developmentGO:00605371100.035
regulation of nucleocytoplasmic transportGO:004682220.035
positive regulation of apoptotic signaling pathwayGO:200123510.035
mitochondrion organizationGO:000700540.035
cellular component assembly involved in morphogenesisGO:00109271070.035
response to light stimulusGO:0009416460.035
positive regulation of cell adhesionGO:004578510.035
neuron neuron synaptic transmissionGO:000727010.035
entrainment of circadian clockGO:000964920.035
regulation of protein metabolic processGO:0051246560.035
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.035
chordate embryonic developmentGO:00430092710.034
regulation of apoptotic processGO:0042981980.034
regulation of anatomical structure morphogenesisGO:00226031300.034
regulation of nucleic acid templated transcriptionGO:19035062130.034
organic cyclic compound biosynthetic processGO:19013622230.034
regulation of protein catabolic processGO:004217610.034
regulation of protein targetingGO:190353320.034
regulation of localizationGO:00328791040.034
cytokinesisGO:000091030.034
regulation of cellular component organizationGO:0051128860.034
regulation of nucleoside metabolic processGO:000911820.033
maternal determination of anterior posterior axis embryoGO:000835840.033
oxoacid metabolic processGO:0043436310.033
head developmentGO:00603223030.033
gtp catabolic processGO:000618420.033
chemosensory behaviorGO:000763510.033
regulation of cellular protein catabolic processGO:190336210.033
cellular response to external stimulusGO:007149620.033
developmental growthGO:00485891660.033
skeletal system morphogenesisGO:00487051020.033
regulation of nucleotide catabolic processGO:003081120.033
embryonic skeletal system developmentGO:0048706970.033
regulation of intracellular signal transductionGO:1902531570.032
organelle fusionGO:004828430.032
stem cell divisionGO:001714510.032
cell proliferationGO:0008283800.032
brain developmentGO:00074202930.032
gliogenesisGO:0042063450.032
regulation of purine nucleotide catabolic processGO:003312120.032
protein importGO:001703830.032
camera type eye developmentGO:00430102220.032
cell projection morphogenesisGO:00488582440.032
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.032
microtubule organizing center organizationGO:003102310.031
cell matrix adhesionGO:000716040.031
regulation of protein ubiquitinationGO:003139630.031
positive regulation of stress activated mapk cascadeGO:003287430.031
regulation of rna biosynthetic processGO:20011412130.031
adult behaviorGO:003053420.031
regulation of bindingGO:005109830.031
regulation of neural precursor cell proliferationGO:200017730.030
cellular carbohydrate metabolic processGO:004426240.030
negative regulation of catabolic processGO:000989530.030
guanosine containing compound catabolic processGO:190106920.030
negative regulation of metabolic processGO:0009892860.030
negative regulation of cellular metabolic processGO:0031324770.030
enzyme linked receptor protein signaling pathwayGO:00071671060.030
centrosome organizationGO:005129710.030
immune system developmentGO:00025201910.030
regulation of transcription dna templatedGO:00063552130.030
stem cell maintenanceGO:001982740.030
embryonic cranial skeleton morphogenesisGO:0048701900.029
carboxylic acid metabolic processGO:0019752220.029
lamellipodium organizationGO:009758110.029
synaptic growth at neuromuscular junctionGO:005112420.029
anterior posterior pattern specificationGO:00099521520.029
nucleobase containing compound biosynthetic processGO:00346542050.029
regionalizationGO:00030022740.029
compound eye developmentGO:004874920.029
cell projection assemblyGO:0030031640.029
synaptic vesicle transportGO:004848910.029
response to drugGO:004249330.029
positive regulation of cellular amino acid metabolic processGO:004576400.029
positive regulation of metabolic processGO:00098931080.029
cellular response to stressGO:0033554620.028
cellular component disassemblyGO:002241110.028
striated muscle cell developmentGO:00550021080.028
positive regulation of jnk cascadeGO:004633030.028
regulation of protein localization to nucleusGO:190018020.028
phosphorylationGO:0016310690.028
cell deathGO:00082191210.028
striated muscle cell differentiationGO:00511461290.028
regulation of dendrite developmentGO:005077330.028
germ line stem cell maintenanceGO:003071820.028
erk1 and erk2 cascadeGO:007037140.027
peptide transportGO:001583310.027
cellular component biogenesisGO:00440851780.027
meiotic chromosome segregationGO:004513230.027
neurotransmitter secretionGO:000726920.027
nucleic acid templated transcriptionGO:00976591810.027
negative regulation of mapk cascadeGO:004340940.027
regulation of i kappab kinase nf kappab signalingGO:004312240.027
transmembrane transportGO:00550851200.027
single organism cellular localizationGO:1902580460.027
neuroblast proliferationGO:000740520.027
regulation of stem cell differentiationGO:200073640.027
neurological system processGO:0050877620.027
glial cell migrationGO:000834730.026
renal tubule morphogenesisGO:006133310.026
digestive system developmentGO:00551232890.026
positive regulation of nucleoside metabolic processGO:004597910.026
synaptic vesicle localizationGO:009747910.026
epithelial tube morphogenesisGO:00605621480.026
regulation of reproductive processGO:200024140.026
cellular response to organic substanceGO:00713101050.026
establishment of synaptic vesicle localizationGO:009748010.026
muscle cell developmentGO:00550011150.026
transcription dna templatedGO:00063511810.026
response to endogenous stimulusGO:0009719830.026
cell cycle g1 s phase transitionGO:004484310.026
regulation of cellular protein metabolic processGO:0032268520.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.025
striated muscle tissue developmentGO:00147061100.025
meiotic cell cycle processGO:190304630.025
regulation of neurogenesisGO:0050767870.025
cytoplasm organizationGO:000702840.025
negative regulation of gliogenesisGO:001401410.025
protein localization to plasma membraneGO:007265910.025
axon developmentGO:00615641660.025
somitogenesisGO:0001756870.025
positive regulation of cytokine productionGO:000181920.024
cellular localizationGO:0051641970.024
developmental programmed cell deathGO:001062340.024
cellular aromatic compound metabolic processGO:00067252950.024
regulation of synapse assemblyGO:005196330.024
regulation of erk1 and erk2 cascadeGO:007037240.024
glial cell differentiationGO:0010001420.024
regulation of synapse organizationGO:005080730.024
lamellipodium assemblyGO:003003210.024
taxisGO:00423301090.024
positive regulation of macromolecule metabolic processGO:0010604930.024
muscle organ developmentGO:00075171010.024
regulation of phosphorus metabolic processGO:0051174430.023
i kappab kinase nf kappab signalingGO:000724940.023
growthGO:00400071740.023
golgi vesicle transportGO:004819330.023
response to topologically incorrect proteinGO:003596620.023
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.023
digestive tract developmentGO:00485652650.023
regulation of gene expressionGO:00104682650.023
peptidyl threonine phosphorylationGO:001810710.023
neuron projection developmentGO:00311751800.023
g1 s transition of mitotic cell cycleGO:000008210.023
rna biosynthetic processGO:00327741810.023
cartilage developmentGO:0051216960.023
apoptotic process involved in developmentGO:190274220.022
exocytosisGO:000688710.022
negative regulation of response to stimulusGO:00485851040.022
biological adhesionGO:0022610400.022
hemopoiesisGO:00300971830.022
positive regulation of canonical wnt signaling pathwayGO:009026340.022
eye morphogenesisGO:00485921440.022
protein complex assemblyGO:0006461300.022
cellular response to starvationGO:000926710.022
positive regulation of cellular amine metabolic processGO:003324000.022
positive regulation of cell matrix adhesionGO:000195410.022
regulation of gtp catabolic processGO:003312420.022
axon ensheathment in central nervous systemGO:003229120.022
nephron epithelium morphogenesisGO:007208810.021
axonogenesisGO:00074091520.021
positive regulation of gtpase activityGO:004354710.021
negative regulation of signal transductionGO:0009968940.021
embryonic limb morphogenesisGO:003032620.021
locomotor rhythmGO:004547530.021
embryonic skeletal system morphogenesisGO:0048704930.021
catabolic processGO:0009056320.021
positive regulation of neuron apoptotic processGO:004352510.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
regulation of protein bindingGO:004339330.021
skeletal system developmentGO:00015011810.021
positive regulation of nucleotide catabolic processGO:003081310.021
retina development in camera type eyeGO:00600411460.021
positive regulation of gtp catabolic processGO:003312610.021
peptidyl threonine modificationGO:001821010.021
cell adhesionGO:0007155400.021
positive regulation of programmed cell deathGO:0043068290.021
ameboidal type cell migrationGO:00016671430.021
nitric oxide biosynthetic processGO:000680920.021
eye developmentGO:00016542770.020
gastrulationGO:00073692080.020
regulation of phosphate metabolic processGO:0019220430.020
positive regulation of secretion by cellGO:190353210.020
muscle cell migrationGO:001481240.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
protein stabilizationGO:005082120.020
negative regulation of cytoplasmic transportGO:190365020.020
embryonic pattern specificationGO:0009880440.020
macromolecule localizationGO:0033036540.020
fertilizationGO:000956630.020
regulation of wnt signaling pathwayGO:0030111530.020
microtubule cytoskeleton organizationGO:0000226330.020
skeletal muscle organ developmentGO:0060538780.020
chemotaxisGO:00069351040.020
regulation of gtpase activityGO:004308720.020
nitric oxide metabolic processGO:004620920.020
regulation of skeletal muscle fiber developmentGO:004874220.020
regulation of proteolysisGO:0030162240.020
transmission of nerve impulseGO:0019226190.020
circulatory system processGO:0003013870.020
cell part morphogenesisGO:00329902460.020
neurotransmitter transportGO:000683620.020
regulation of mrna processingGO:005068430.019
homeostatic processGO:00425921420.019
regulation of establishment of protein localization to plasma membraneGO:009000310.019
signal transduction in absence of ligandGO:003803410.019
regulation of metal ion transportGO:001095940.019
spindle assemblyGO:005122520.019
cellular response to nutrient levelsGO:003166920.019
establishment of epithelial cell polarityGO:009016220.019
cellular respirationGO:004533330.019
activation of mapk activityGO:000018730.019
positive regulation of muscle cell differentiationGO:005114910.019
positive regulation of gene expressionGO:0010628710.019
negative regulation of cell communicationGO:0010648960.019
regulation of stem cell proliferationGO:007209120.019
regulation of reactive oxygen species metabolic processGO:200037720.019
positive regulation of cytoskeleton organizationGO:005149530.019
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.018
positive regulation of cellular component biogenesisGO:004408930.018
nucleobase containing compound metabolic processGO:00061392740.018
nephron morphogenesisGO:007202820.018
regulation of hormone secretionGO:004688320.018
regulation of chromosome segregationGO:005198310.018
positive regulation of stem cell proliferationGO:200064810.018
adherens junction maintenanceGO:003433420.018
cellular response to endogenous stimulusGO:0071495680.018
regulation of skeletal muscle tissue developmentGO:004864140.018
regulation of synaptic growth at neuromuscular junctionGO:000858210.018
actomyosin structure organizationGO:0031032530.018
reactive oxygen species biosynthetic processGO:190340910.018
regulation of carbohydrate metabolic processGO:000610940.018
spermatid differentiationGO:004851520.018
multicellular organismal signalingGO:0035637220.018
regulation of cell sizeGO:0008361290.018
regulation of protein complex assemblyGO:004325430.018
nuclear exportGO:005116810.018
neuron projection morphogenesisGO:00488121610.018
gland developmentGO:00487321430.018
release of sequestered calcium ion into cytosolGO:005120930.018
positive regulation of i kappab kinase nf kappab signalingGO:004312330.018
action potentialGO:0001508190.018
nucleobase containing compound transportGO:001593120.018
regulation of protein localization to plasma membraneGO:190307610.017
macromolecule catabolic processGO:0009057150.017
negative regulation of apoptotic processGO:0043066550.017
cell cycle arrestGO:000705010.017
determination of heart left right asymmetryGO:00613711170.017
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.017
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.017
regulation of cell substrate adhesionGO:001081010.017
er nucleus signaling pathwayGO:000698420.017
connective tissue developmentGO:0061448990.017
hormone transportGO:000991420.017
cilium morphogenesisGO:0060271850.017
negative regulation of macromolecule metabolic processGO:0010605760.017
regulation of cellular carbohydrate metabolic processGO:001067540.017
negative regulation of signalingGO:0023057960.017
response to woundingGO:00096111160.017
heart morphogenesisGO:00030071560.017
positive regulation of cell communicationGO:0010647560.017
negative regulation of intracellular transportGO:003238730.017
homeostasis of number of cellsGO:0048872620.017
regulation of tube sizeGO:003515020.017
positive regulation of apoptotic processGO:0043065290.017
carbohydrate biosynthetic processGO:001605110.017
regulation of catalytic activityGO:0050790550.017
female meiotic divisionGO:000714320.017
multi organism processGO:00517041340.017
response to external biotic stimulusGO:0043207970.017
actin polymerization or depolymerizationGO:000815420.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
positive regulation of response to stimulusGO:0048584800.017
axon extensionGO:0048675450.017
cellular response to molecule of bacterial originGO:007121930.017
skeletal muscle tissue developmentGO:0007519670.017
negative regulation of cytokine productionGO:000181810.017
calcium ion transport into cytosolGO:006040230.017
cilium assemblyGO:0042384580.017
negative regulation of programmed cell deathGO:0043069580.016
regulation of axonogenesisGO:0050770320.016
single organism membrane fusionGO:004480120.016
organelle localizationGO:0051640490.016
sequestering of calcium ionGO:005120830.016
regulation of cell activationGO:005086510.016
nephron tubule morphogenesisGO:007207810.016
heart loopingGO:0001947940.016
leukocyte homeostasisGO:000177620.016
regulation of cellular ketone metabolic processGO:001056570.016
determination of left right symmetryGO:00073681790.016
embryonic heart tube morphogenesisGO:00031431080.016
negative regulation of cell deathGO:0060548600.016
positive regulation of cell divisionGO:005178120.016
atp catabolic processGO:000620040.016
cellular response to extracellular stimulusGO:003166820.016
actin filament polymerizationGO:003004120.016
membrane fusionGO:006102520.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
endoplasmic reticulum unfolded protein responseGO:003096820.016
positive regulation of secretionGO:005104710.016
organic substance catabolic processGO:1901575280.016
macromolecular complex subunit organizationGO:0043933740.016
protein phosphorylationGO:0006468470.016
cell adhesion mediated by integrinGO:003362710.016
outflow tract morphogenesisGO:000315110.016
positive regulation of signal transductionGO:0009967560.016
histone phosphorylationGO:001657220.016
forebrain cell migrationGO:002188510.016
cellular response to lipopolysaccharideGO:007122230.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
negative regulation of developmental processGO:0051093650.016
mitotic cell cycle processGO:1903047480.016
adherens junction organizationGO:003433240.016
protein complex subunit organizationGO:0071822460.015
regulation of photoreceptor cell differentiationGO:004653220.015

flii disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
musculoskeletal system diseaseDOID:1700.017
muscular diseaseDOID:008000000.016
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
disease of metabolismDOID:001466700.015