Danio rerio

39 known processes

sod1

superoxide dismutase 1, soluble

(Aliases: ZSOD,cuzn,Cu/Zn-SOD)

sod1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to superoxideGO:000030320.726
cellular respirationGO:004533330.619
Yeast
cellular modified amino acid metabolic processGO:000657530.590
Mouse
cellular response to superoxideGO:007145120.537
removal of superoxide radicalsGO:001943020.536
cellular response to oxygen radicalGO:007145020.507
larval developmentGO:000216420.482
response to transition metal nanoparticleGO:1990267280.436
aromatic compound biosynthetic processGO:00194382170.421
Yeast
agingGO:000756820.420
Human Yeast Mouse Fly
hydrogen peroxide metabolic processGO:004274320.387
Human Mouse
response to stressGO:00069502630.316
regulation of cell communicationGO:00106462320.313
Human Mouse
signal transductionGO:00071654550.289
Human Mouse
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.267
Human
response to metal ionGO:0010038340.256
cellular component assemblyGO:00226071700.255
cellular macromolecule biosynthetic processGO:00346452240.254
Yeast
neuron differentiationGO:00301823530.250
Mouse
response to external stimulusGO:00096052640.249
positive regulation of biological processGO:00485182530.248
Human Yeast Mouse
regulation of nitrogen compound metabolic processGO:00511712510.213
Human Yeast
response to copper ionGO:0046688130.204
cellular nitrogen compound metabolic processGO:00346412900.198
Human Yeast Mouse
regulation of rna biosynthetic processGO:20011412130.196
Yeast
superoxide metabolic processGO:000680120.192
negative regulation of signal transductionGO:0009968940.186
regulation of cellular metabolic processGO:00313233200.186
Human Yeast Mouse Fly
negative regulation of cell communicationGO:0010648960.177
response to hydrogen peroxideGO:004254230.175
Mouse
protein complex biogenesisGO:0070271300.173
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.167
cellular nitrogen compound biosynthetic processGO:00442712180.164
Yeast
regulation of biosynthetic processGO:00098892500.164
Human Yeast
regulation of macromolecule biosynthetic processGO:00105562250.158
Yeast
macromolecular complex subunit organizationGO:0043933740.158
regulation of metabolic processGO:00192223590.156
Human Yeast Mouse Fly
regulation of primary metabolic processGO:00800903110.155
Human Yeast Mouse
small molecule catabolic processGO:004428230.153
macromolecule biosynthetic processGO:00090592270.153
Yeast
reactive nitrogen species metabolic processGO:200105700.152
response to reactive oxygen speciesGO:000030250.151
protein metabolic processGO:00195381830.149
Human Mouse
regulation of reactive oxygen species metabolic processGO:200037720.148
Human
cellular macromolecule metabolic processGO:00442603910.147
Human Yeast Mouse
heart developmentGO:00075073130.143
negative regulation of programmed cell deathGO:0043069580.141
Mouse
regulation of signal transductionGO:00099662250.139
Human Mouse
regulation of cellular response to oxidative stressGO:190040720.138
Human
iron ion homeostasisGO:005507240.136
Mouse
regulation of response to oxidative stressGO:190288220.135
Human
regulation of macromolecule metabolic processGO:00602553170.134
Human Yeast Mouse
maintenance of locationGO:005123540.131
response to drugGO:004249330.129
Mouse
organic cyclic compound metabolic processGO:19013603010.128
Human Yeast
cellular amide metabolic processGO:004360340.127
Mouse
response to inorganic substanceGO:0010035380.127
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.126
Human
cellular component biogenesisGO:00440851780.125
locomotory behaviorGO:0007626340.124
Mouse
nitrogen compound metabolic processGO:00068073190.122
Human Yeast Mouse
lipid storageGO:001991510.117
regulation of cellular macromolecule biosynthetic processGO:20001122220.117
Yeast
positive regulation of metabolic processGO:00098931080.116
Human Yeast Mouse
gland developmentGO:00487321430.116
regulation of signalingGO:00230512350.116
Human Mouse
intracellular signal transductionGO:0035556850.113
Human Mouse
regulation of oxidative stress induced cell deathGO:190320120.113
Human
regulation of autophagyGO:001050630.111
Fly
response to oxidative stressGO:0006979110.111
small molecule metabolic processGO:0044281770.110
Human Mouse
cell surface receptor signaling pathwayGO:00071663250.110
regulation of rna metabolic processGO:00512522240.107
Yeast
regulation of biological qualityGO:00650082630.106
muscle cell differentiationGO:00426921390.105
regulation of transcription dna templatedGO:00063552130.103
Yeast
nucleobase containing compound biosynthetic processGO:00346542050.103
Yeast
negative regulation of response to stimulusGO:00485851040.103
immune system processGO:00023762410.101
Mouse
liver developmentGO:0001889960.101
protein homooligomerizationGO:005126030.096
positive regulation of transportGO:005105020.096
regulation of tube sizeGO:003515020.094
Mouse
heart morphogenesisGO:00030071560.092
reactive oxygen species metabolic processGO:007259360.091
cellular response to reactive oxygen speciesGO:003461420.090
regulation of response to stimulusGO:00485832690.086
Human Mouse
organic substance biosynthetic processGO:19015762890.085
Human Yeast
protein complex assemblyGO:0006461300.083
single organism metabolic processGO:00447102170.083
regulation of cellular carbohydrate metabolic processGO:001067540.082
protein complex subunit organizationGO:0071822460.082
oxoacid metabolic processGO:0043436310.080
Mouse
nucleic acid templated transcriptionGO:00976591810.080
Yeast
cellular amino acid metabolic processGO:000652070.079
Mouse
negative regulation of biological processGO:00485193040.077
Human Yeast Mouse
negative regulation of cellular processGO:00485232830.077
Yeast Mouse
response to chemicalGO:00422213200.076
extrinsic apoptotic signaling pathwayGO:009719130.075
regulation of developmental processGO:00507932470.074
Mouse
regulation of blood vessel sizeGO:005088020.074
Mouse
respiratory electron transport chainGO:002290420.072
transmembrane transportGO:00550851200.070
peptide metabolic processGO:000651810.070
Mouse
organic cyclic compound biosynthetic processGO:19013622230.069
Human Yeast
macromolecular complex assemblyGO:0065003350.068
multicellular organism growthGO:003526440.067
Mouse
cellular response to molecule of bacterial originGO:007121930.067
reactive oxygen species biosynthetic processGO:190340910.067
Human Mouse
hepaticobiliary system developmentGO:0061008980.066
negative regulation of signalingGO:0023057960.066
regulation of cellular biosynthetic processGO:00313262450.066
Yeast
regulation of response to stressGO:0080134360.066
Human
rna metabolic processGO:00160702190.066
Yeast
cell migrationGO:00164772370.065
organic acid metabolic processGO:0006082310.065
Mouse
embryo development ending in birth or egg hatchingGO:00097922710.064
regulation of multicellular organismal processGO:00512392770.063
Human Mouse
positive regulation of cellular metabolic processGO:0031325940.063
Human Yeast Mouse
heterocycle metabolic processGO:00464832900.062
Human Yeast
transcription dna templatedGO:00063511810.062
Yeast
cellular response to lipopolysaccharideGO:007122230.062
regulation of nucleobase containing compound metabolic processGO:00192192500.062
Human Yeast
regulation of transmembrane transportGO:0034762180.061
alpha amino acid metabolic processGO:190160530.061
neuron developmentGO:00486662620.060
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:200123630.060
mitochondrion organizationGO:000700540.059
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.058
programmed cell deathGO:00125011190.058
Human Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.058
Yeast
regulation of cytokine productionGO:000181730.057
Human
nucleic acid metabolic processGO:00903042440.056
Yeast
atp catabolic processGO:000620040.055
cellular biosynthetic processGO:00442492860.055
Human Yeast Mouse
regulation of systemic arterial blood pressureGO:000307310.054
positive regulation of map kinase activityGO:004340630.053
Mouse
protein oligomerizationGO:005125970.052
positive regulation of cytokine productionGO:000181920.051
Human
sulfur compound metabolic processGO:0006790130.051
Mouse
rna biosynthetic processGO:00327741810.051
Yeast
response to nutrientGO:000758430.051
metal ion homeostasisGO:0055065260.051
Yeast Mouse
cell morphogenesisGO:00009022890.050
Mouse
locomotionGO:00400113130.048
regulation of protein localization to nucleusGO:190018020.048
cellular carbohydrate metabolic processGO:004426240.047
cell death in response to oxidative stressGO:003647320.047
Human
neurological system processGO:0050877620.046
Mouse
cell cell signalingGO:0007267520.046
hematopoietic or lymphoid organ developmentGO:00485341910.046
adult behaviorGO:003053420.045
nucleoside monophosphate catabolic processGO:000912540.044
energy reserve metabolic processGO:000611220.044
homeostatic processGO:00425921420.044
response to uvGO:000941130.043
carboxylic acid metabolic processGO:0019752220.043
Mouse
response to temperature stimulusGO:0009266150.043
Mouse
cellular response to stressGO:0033554620.042
apoptotic processGO:00069151160.042
Human Mouse
organonitrogen compound metabolic processGO:1901564740.042
Human Mouse
single organism organelle organizationGO:19025891990.042
Mouse
biosynthetic processGO:00090582940.041
Human Yeast Mouse
regulation of cell differentiationGO:00455951420.041
transition metal ion homeostasisGO:005507650.040
Yeast Mouse
regulation of metal ion transportGO:001095940.040
macromolecule localizationGO:0033036540.040
nucleobase containing compound metabolic processGO:00061392740.040
Human Yeast
cellular component movementGO:00069283350.040
Mouse
response to other organismGO:0051707970.039
cation homeostasisGO:0055080330.038
Yeast Mouse
neurotransmitter transportGO:000683620.038
circulatory system processGO:0003013870.038
Human Mouse
erk1 and erk2 cascadeGO:007037140.037
response to oxygen radicalGO:000030520.037
cellular response to drugGO:003569010.037
response to abiotic stimulusGO:00096281220.036
Mouse
regulation of protein transportGO:005122330.035
electron transport chainGO:002290020.035
cation transmembrane transportGO:0098655650.035
nitric oxide biosynthetic processGO:000680920.034
cell deathGO:00082191210.034
Human Mouse
organic substance catabolic processGO:1901575280.034
Human
regulation of membrane potentialGO:0042391230.034
Human
carboxylic acid catabolic processGO:004639530.034
cell projection morphogenesisGO:00488582440.034
system processGO:00030081850.033
Human Mouse
regulation of establishment of protein localizationGO:007020140.033
cellular response to chemical stimulusGO:00708871570.032
cellular amino acid biosynthetic processGO:000865220.032
regulation of erk1 and erk2 cascadeGO:007037240.032
response to external biotic stimulusGO:0043207970.032
negative regulation of developmental processGO:0051093650.032
regulation of cellular ketone metabolic processGO:001056570.031
muscle cell migrationGO:001481240.031
single organism localizationGO:19025782250.030
Mouse
regulation of intracellular signal transductionGO:1902531570.030
Human Mouse
cellular ketone metabolic processGO:0042180110.030
regulation of programmed cell deathGO:00430671010.030
Human Mouse
cellular response to biotic stimulusGO:007121630.030
inorganic cation transmembrane transportGO:0098662500.030
dicarboxylic acid metabolic processGO:004364810.030
positive regulation of cellular processGO:00485222010.030
Human Yeast Mouse
axon guidanceGO:0007411860.029
kidney developmentGO:0001822920.029
hemopoiesisGO:00300971830.029
protein modification processGO:00362111000.029
Human Mouse
inorganic ion transmembrane transportGO:0098660570.028
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.028
nitric oxide metabolic processGO:004620920.028
cellular component morphogenesisGO:00329893360.028
Mouse
negative regulation of intrinsic apoptotic signaling pathwayGO:200124380.028
nucleocytoplasmic transportGO:000691340.028
response to glucocorticoidGO:005138410.027
generation of precursor metabolites and energyGO:000609150.027
Yeast
carbohydrate biosynthetic processGO:001605110.027
regulation of cell activationGO:005086510.027
striated muscle tissue developmentGO:00147061100.026
negative regulation of oxidative stress induced cell deathGO:190320220.026
muscle structure developmentGO:00610611960.026
transportGO:00068102200.026
Mouse
nuclear transportGO:005116940.026
regulation of carbohydrate metabolic processGO:000610940.025
melanosome transportGO:0032402190.024
protein acetylationGO:000647320.024
cell agingGO:000756920.024
Human Yeast
cellular response to oxygen containing compoundGO:1901701200.024
establishment of localizationGO:00512342440.024
Mouse
regulation of apoptotic processGO:0042981980.024
Human Mouse
response to coldGO:000940940.024
negative regulation of apoptotic signaling pathwayGO:2001234100.024
leukocyte proliferationGO:007066110.023
pigmentationGO:0043473850.023
peptidyl serine phosphorylationGO:001810510.023
neuron neuron synaptic transmissionGO:000727010.023
androgen biosynthetic processGO:000670210.023
response to bacteriumGO:0009617580.022
single organism transportGO:00447652060.022
Mouse
negative regulation of cell deathGO:0060548600.022
Mouse
neuron projection guidanceGO:0097485860.022
negative regulation of intracellular signal transductionGO:1902532220.022
vascular process in circulatory systemGO:000301860.022
Mouse
head developmentGO:00603223030.021
guanosine containing compound metabolic processGO:190106840.021
Human
regulation of protein catabolic processGO:004217610.021
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.021
oxidation reduction processGO:0055114410.021
gene expressionGO:00104672520.020
Yeast
positive regulation of cellular amino acid metabolic processGO:004576400.020
blood circulationGO:0008015870.020
Human Mouse
cell proliferationGO:0008283800.020
positive regulation of macromolecule metabolic processGO:0010604930.020
Yeast Mouse
striated muscle cell differentiationGO:00511461290.019
internal protein amino acid acetylationGO:000647520.019
protein acylationGO:004354330.019
synaptic vesicle localizationGO:009747910.019
brain developmentGO:00074202930.019
positive regulation of immune effector processGO:000269930.019
positive regulation of cell communicationGO:0010647560.019
Human Mouse
transcription from rna polymerase ii promoterGO:0006366800.019
Yeast
regulation of protein metabolic processGO:0051246560.019
Human Mouse
purine nucleoside monophosphate catabolic processGO:000912840.019
negative regulation of cell differentiationGO:0045596460.019
chemotaxisGO:00069351040.019
regulation of carbohydrate biosynthetic processGO:004325510.018
immune system developmentGO:00025201910.018
cellular protein metabolic processGO:00442671290.018
Human Mouse
response to axon injuryGO:0048678140.018
Mouse
regulation of cytoplasmic transportGO:190364940.018
response to biotic stimulusGO:0009607970.018
behaviorGO:0007610740.018
Mouse
cell part morphogenesisGO:00329902460.018
cell morphogenesis involved in differentiationGO:00009041950.018
Mouse
striated muscle cell developmentGO:00550021080.018
positive regulation of secretionGO:005104710.018
response to activityGO:0014823140.018
muscle cell developmentGO:00550011150.018
regulation of cysteine type endopeptidase activityGO:2000116210.018
regulation of intracellular protein transportGO:003315730.018
negative regulation of intracellular transportGO:003238730.017
organelle fusionGO:004828430.017
regulation of cell substrate adhesionGO:001081010.017
response to cadmium ionGO:0046686140.017
dopamine biosynthetic processGO:004241620.017
positive regulation of cell adhesionGO:004578510.017
detection of chemical stimulusGO:000959340.017
negative regulation of epithelial cell proliferationGO:005068010.017
sensory organ developmentGO:00074233930.017
Mouse
negative regulation of protein processingGO:0010955100.017
regulation of transporter activityGO:003240920.017
proteasomal protein catabolic processGO:001049820.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
i kappab kinase nf kappab signalingGO:000724940.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
macromolecule modificationGO:00434121110.017
Human Mouse
purine ribonucleoside monophosphate catabolic processGO:000916940.017
regulation of cellular response to stressGO:0080135200.017
Human
activation of mapk activityGO:000018730.017
Mouse
positive regulation of cell substrate adhesionGO:001081110.017
protein stabilizationGO:005082120.016
Yeast
production of molecular mediator of immune responseGO:000244020.016
regulation of phosphate metabolic processGO:0019220430.016
Human Mouse
negative regulation of protein transportGO:005122430.016
organelle organizationGO:00069962270.016
Mouse
cation transportGO:0006812810.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
Yeast
muscle tissue developmentGO:00605371100.016
positive regulation of cellular amine metabolic processGO:003324000.016
intrinsic apoptotic signaling pathwayGO:0097193200.016
Human
specification of symmetryGO:00097992040.016
regulation of epithelial cell proliferationGO:005067830.016
ion transportGO:00068111140.016
regulation of hydrolase activityGO:0051336280.016
Human
g1 s transition of mitotic cell cycleGO:000008210.016
regulation of apoptotic signaling pathwayGO:2001233120.016
Human
very long chain fatty acid biosynthetic processGO:004276140.016
axonogenesisGO:00074091520.016
negative regulation of protein phosphorylationGO:000193340.016
negative regulation of kinase activityGO:003367340.016
synaptic vesicle transportGO:004848910.015
negative regulation of apoptotic processGO:0043066550.015
Mouse
cellular response to nutrient levelsGO:003166920.015
regulation of localizationGO:00328791040.015
negative regulation of mapk cascadeGO:004340940.015
regulation of endopeptidase activityGO:0052548230.015
cytoskeleton organizationGO:0007010960.015
Mouse
nuclear exportGO:005116810.015
deathGO:00162651210.015
Human Mouse
response to organic substanceGO:00100331530.015
establishment of protein localization to organelleGO:007259440.015
regulation of cellular amine metabolic processGO:003323800.015
endosomal transportGO:001619720.015
negative regulation of protein maturationGO:1903318100.015
regulation of response to biotic stimulusGO:000283120.014
regulation of cell proliferationGO:0042127370.014
calcium ion transport into cytosolGO:006040230.014
regulation of nucleocytoplasmic transportGO:004682220.014
regulation of transmembrane transporter activityGO:002289820.014
fatty acid beta oxidationGO:000663510.014
myotube differentiationGO:0014902450.014
urogenital system developmentGO:0001655970.014
regulation of anatomical structure sizeGO:0090066330.014
Mouse
protein modification by small protein removalGO:007064610.014
stem cell maintenanceGO:001982740.014
regulation of sequestering of calcium ionGO:005128240.014
pigment granule localizationGO:0051875250.014
negative regulation of cytoplasmic transportGO:190365020.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
Yeast
regulation of dendrite developmentGO:005077330.014
lipid oxidationGO:003444010.014
regulation of protein ubiquitinationGO:003139630.014
regulation of molecular functionGO:0065009700.014
Human Yeast Mouse
ribonucleoside monophosphate catabolic processGO:000915840.014
regulation of production of molecular mediator of immune responseGO:000270010.014
cellular catabolic processGO:0044248270.014
Human Fly
inner ear developmentGO:00488391260.013
Mouse
negative regulation of signal transduction in absence of ligandGO:190109910.013
negative regulation of protein kinase activityGO:000646940.013
regulation of muscle contractionGO:000693730.013
Mouse
protein import into nucleusGO:000660630.013
catabolic processGO:0009056320.013
Human Fly
response to corticosteroidGO:003196010.013
regulation of reproductive processGO:200024140.013
signal transduction by phosphorylationGO:0023014180.013
Mouse
metal ion transportGO:0030001580.013
regulation of cell deathGO:00109411030.013
Human Mouse
regulation of nucleoside metabolic processGO:000911820.013
Human
sensory perception of chemical stimulusGO:000760630.013
cellular response to oxidative stressGO:003459950.013
androgen metabolic processGO:000820920.013
nuclear importGO:005117030.012
cellular response to extracellular stimulusGO:003166820.012
regulation of peptidase activityGO:0052547230.012
regulation of gene expressionGO:00104682650.012
Yeast
regulation of i kappab kinase nf kappab signalingGO:004312240.012
neuron deathGO:0070997210.012
Mouse
negative regulation of response to dna damage stimulusGO:200102130.012
single organism reproductive processGO:0044702400.012
Mouse
cell type specific apoptotic processGO:0097285220.012
Mouse
signal transduction in absence of ligandGO:003803410.012
organic acid catabolic processGO:001605430.012
cellular protein modification processGO:00064641000.012
Human Mouse
cellular aromatic compound metabolic processGO:00067252950.012
Human Yeast
fatty acid oxidationGO:001939510.012
negative regulation of protein complex assemblyGO:003133310.012
cellular response to external stimulusGO:007149620.012
regulation of cellular amino acid metabolic processGO:000652100.012
phosphorus metabolic processGO:00067931090.012
Human Mouse
protein localizationGO:0008104400.012
protein importGO:001703830.012
growthGO:00400071740.012
Mouse
sequestering of metal ionGO:005123830.012
muscle fiber developmentGO:0048747520.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
negative regulation of catabolic processGO:000989530.011
regulation of system processGO:0044057400.011
Mouse
positive regulation of nucleic acid templated transcriptionGO:1903508570.011
Yeast
ion homeostasisGO:0050801410.011
Yeast Mouse
regulation of neuron apoptotic processGO:0043523170.011
Mouse
positive regulation of biosynthetic processGO:0009891680.011
Yeast
cell fate commitmentGO:0045165990.011
cytosolic calcium ion transportGO:006040130.011
regulation of bindingGO:005109830.011
carboxylic acid biosynthetic processGO:0046394120.011
neuron apoptotic processGO:0051402200.011
Mouse
protein dephosphorylationGO:000647030.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
negative regulation of proteolysisGO:0045861100.011
regulation of response to external stimulusGO:0032101310.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.011
peptidyl serine modificationGO:001820920.011
positive regulation of secretion by cellGO:190353210.011
release of sequestered calcium ion into cytosolGO:005120930.011
positive regulation of cell activationGO:005086710.011
tight junction assemblyGO:007083010.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
gtp metabolic processGO:004603940.011
Human
female sex differentiationGO:004666040.010
Mouse
generation of neuronsGO:00486993850.010
Mouse
protein localization to nucleusGO:003450430.010
immune responseGO:0006955280.010
single organism nuclear importGO:190259330.010
cell projection organizationGO:00300302840.010
Mouse
epithelial tube morphogenesisGO:00605621480.010
cardiac muscle tissue developmentGO:0048738480.010
neuron projection morphogenesisGO:00488121610.010
pigment granule transportGO:0051904190.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
Yeast

sod1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.030
inherited metabolic disorderDOID:65500.030
mitochondrial metabolism diseaseDOID:70000.020
leigh diseaseDOID:365200.020
synucleinopathyDOID:005089000.018
central nervous system diseaseDOID:33100.018
Human
nervous system diseaseDOID:86300.018
Human
disease of anatomical entityDOID:700.018
Human
neurodegenerative diseaseDOID:128900.018
Human
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011