Danio rerio

13 known processes

chd8

chromodomain helicase DNA binding protein 8

(Aliases: fi45h08,wu:fi45h08,CHD-8,si:ch211-10e2.6)

chd8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nitrogen compound metabolic processGO:00068073190.081
cellular macromolecule metabolic processGO:00442603910.079
regulation of cellular macromolecule biosynthetic processGO:20001122220.067
nucleobase containing compound biosynthetic processGO:00346542050.064
nucleic acid metabolic processGO:00903042440.059
regulation of transcription dna templatedGO:00063552130.056
signal transductionGO:00071654550.055
cellular nitrogen compound biosynthetic processGO:00442712180.055
organic cyclic compound metabolic processGO:19013603010.048
oxoacid metabolic processGO:0043436310.047
organic cyclic compound biosynthetic processGO:19013622230.045
amine metabolic processGO:000930820.044
regulation of cellular amine metabolic processGO:003323800.044
heterocycle biosynthetic processGO:00181302150.043
regulation of establishment of protein localizationGO:007020140.042
organic acid metabolic processGO:0006082310.042
gene expressionGO:00104672520.041
macromolecule biosynthetic processGO:00090592270.040
rna biosynthetic processGO:00327741810.040
rna metabolic processGO:00160702190.040
regulation of protein transportGO:005122330.040
negative regulation of cellular processGO:00485232830.040
immune system processGO:00023762410.039
positive regulation of transportGO:005105020.039
regulation of multicellular organism growthGO:004001440.038
organic substance biosynthetic processGO:19015762890.038
regulation of gene expressionGO:00104682650.038
eye developmentGO:00016542770.038
regulation of nucleobase containing compound metabolic processGO:00192192500.036
nucleocytoplasmic transportGO:000691340.036
agingGO:000756820.036
cellular amine metabolic processGO:004410620.036
neuron developmentGO:00486662620.035
purine nucleoside monophosphate catabolic processGO:000912840.035
regulation of response to stimulusGO:00485832690.035
regulation of primary metabolic processGO:00800903110.035
heterocycle metabolic processGO:00464832900.033
positive regulation of cell cycleGO:004578730.033
cellular aromatic compound metabolic processGO:00067252950.033
regulation of cellular amino acid metabolic processGO:000652100.033
regulation of biosynthetic processGO:00098892500.032
negative regulation of biological processGO:00485193040.032
glucose homeostasisGO:004259310.032
larval developmentGO:000216420.032
aromatic compound biosynthetic processGO:00194382170.032
nucleobase containing compound metabolic processGO:00061392740.032
cilium movementGO:0003341260.031
regulation of nucleic acid templated transcriptionGO:19035062130.031
peptidyl lysine acetylationGO:001839420.031
transcription dna templatedGO:00063511810.031
regulation of nitrogen compound metabolic processGO:00511712510.030
nucleoside monophosphate catabolic processGO:000912540.030
nucleic acid templated transcriptionGO:00976591810.030
cellular ketone metabolic processGO:0042180110.030
cellular biosynthetic processGO:00442492860.029
meiotic nuclear divisionGO:000712640.029
small molecule metabolic processGO:0044281770.029
cell morphogenesisGO:00009022890.029
cellular nitrogen compound metabolic processGO:00346412900.028
head developmentGO:00603223030.028
regulation of macromolecule biosynthetic processGO:00105562250.028
regulation of macromolecule metabolic processGO:00602553170.028
muscle fiber developmentGO:0048747520.028
positive regulation of cytoskeleton organizationGO:005149530.028
cell matrix adhesionGO:000716040.028
purine ribonucleoside monophosphate catabolic processGO:000916940.028
regulation of cellular ketone metabolic processGO:001056570.028
regulation of cytoplasmic transportGO:190364940.028
cellular amino acid metabolic processGO:000652070.027
multicellular organism growthGO:003526440.027
peptide transportGO:001583310.027
organonitrogen compound metabolic processGO:1901564740.027
regulation of metabolic processGO:00192223590.027
regulation of cellular metabolic processGO:00313233200.026
protein acetylationGO:000647320.026
carboxylic acid metabolic processGO:0019752220.026
positive regulation of biological processGO:00485182530.026
regulation of rna metabolic processGO:00512522240.026
ubiquitin dependent protein catabolic processGO:000651130.025
regulation of cell differentiationGO:00455951420.025
regulation of signalingGO:00230512350.025
regulation of dendrite developmentGO:005077330.025
ribonucleoside monophosphate catabolic processGO:000915840.025
central nervous system developmentGO:00074173870.025
regulation of intracellular protein transportGO:003315730.024
establishment of protein localization to plasma membraneGO:009000210.024
exocytosisGO:000688710.024
atp catabolic processGO:000620040.024
embryonic organ developmentGO:00485683810.024
nuclear exportGO:005116810.024
biosynthetic processGO:00090582940.024
digestive tract developmentGO:00485652650.024
cell substrate adhesionGO:003158940.024
cell projection organizationGO:00300302840.024
protein acylationGO:004354330.023
regulation of rna biosynthetic processGO:20011412130.023
organelle organizationGO:00069962270.023
vasculature developmentGO:00019442780.023
morphogenesis of an epitheliumGO:00020093330.023
regulation of nucleoside metabolic processGO:000911820.023
guanosine containing compound metabolic processGO:190106840.023
cellular macromolecule biosynthetic processGO:00346452240.022
single organism organelle organizationGO:19025891990.022
gtp catabolic processGO:000618420.022
sensory organ developmentGO:00074233930.022
regulation of nucleocytoplasmic transportGO:004682220.022
muscle cell developmentGO:00550011150.022
regulation of bindingGO:005109830.022
regulation of cytokine productionGO:000181730.022
response to stressGO:00069502630.022
regulation of multicellular organismal processGO:00512392770.022
internal protein amino acid acetylationGO:000647520.022
regulation of biological qualityGO:00650082630.022
gtp metabolic processGO:004603940.022
positive regulation of secretion by cellGO:190353210.022
nuclear migrationGO:000709730.022
maintenance of locationGO:005123540.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
regulation of apoptotic processGO:0042981980.022
negative regulation of protein kinase activityGO:000646940.022
nuclear transportGO:005116940.021
regulation of dendrite morphogenesisGO:004881430.021
regulation of metal ion transportGO:001095940.021
protein metabolic processGO:00195381830.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
cellular protein catabolic processGO:004425740.021
golgi vesicle transportGO:004819330.021
gastrulationGO:00073692080.021
hormone transportGO:000991420.021
cell projection morphogenesisGO:00488582440.021
response to chemicalGO:00422213200.021
amino acid transportGO:000686520.021
synaptic vesicle localizationGO:009747910.021
regulation of multicellular organismal developmentGO:20000262230.021
negative regulation of protein transportGO:005122430.020
regulation of cellular biosynthetic processGO:00313262450.020
positive regulation of cellular amine metabolic processGO:003324000.020
cognitionGO:005089010.020
carbohydrate homeostasisGO:003350010.020
extrinsic apoptotic signaling pathwayGO:009719130.020
regulation of synaptic plasticityGO:004816710.020
blood vessel morphogenesisGO:00485142160.020
regulation of synapse organizationGO:005080730.020
cellular component biogenesisGO:00440851780.020
establishment of localizationGO:00512342440.020
regulation of mrna processingGO:005068430.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
modification dependent macromolecule catabolic processGO:004363230.020
rna localizationGO:000640340.020
hemopoiesisGO:00300971830.019
guanosine containing compound catabolic processGO:190106920.019
carbohydrate derivative biosynthetic processGO:1901137430.019
hormone secretionGO:004687920.019
phagocytosisGO:000690930.019
internal peptidyl lysine acetylationGO:001839320.019
regulation of synapse assemblyGO:005196330.019
protein importGO:001703830.019
protein localization to plasma membraneGO:007265910.019
carbohydrate biosynthetic processGO:001605110.019
neuron neuron synaptic transmissionGO:000727010.019
cell surface receptor signaling pathwayGO:00071663250.019
single organism transportGO:00447652060.019
macromolecule modificationGO:00434121110.019
single organism metabolic processGO:00447102170.019
camera type eye developmentGO:00430102220.019
stem cell maintenanceGO:001982740.018
immune system developmentGO:00025201910.018
positive regulation of cellular processGO:00485222010.018
regulation of protein ubiquitinationGO:003139630.018
single fertilizationGO:000733830.018
brain developmentGO:00074202930.018
protein dephosphorylationGO:000647030.018
lipid storageGO:001991510.018
cellular component movementGO:00069283350.018
cellular protein metabolic processGO:00442671290.018
anterior posterior pattern specificationGO:00099521520.018
regulation of cell deathGO:00109411030.018
regulation of inflammatory responseGO:005072720.018
proteasomal protein catabolic processGO:001049820.018
striated muscle cell developmentGO:00550021080.018
transcription from rna polymerase ii promoterGO:0006366800.018
chordate embryonic developmentGO:00430092710.018
transportGO:00068102200.018
regulation of purine nucleotide catabolic processGO:003312120.017
positive regulation of biosynthetic processGO:0009891680.017
apoptotic processGO:00069151160.017
compound eye developmentGO:004874920.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
positive regulation of cellular component biogenesisGO:004408930.017
regulation of hormone secretionGO:004688320.017
synaptic vesicle transportGO:004848910.017
small molecule catabolic processGO:004428230.017
fertilizationGO:000956630.017
negative regulation of secretionGO:005104820.017
generation of neuronsGO:00486993850.017
erk1 and erk2 cascadeGO:007037140.017
regulation of nucleotide catabolic processGO:003081120.017
neuron differentiationGO:00301823530.017
negative regulation of protein phosphorylationGO:000193340.017
regulation of protein targetingGO:190353320.017
cellular response to external stimulusGO:007149620.017
heart developmentGO:00075073130.017
negative regulation of kinase activityGO:003367340.017
pronuclear migrationGO:003504610.017
tube morphogenesisGO:00352393490.017
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.016
microtubule based movementGO:0007018330.016
regulation of protein bindingGO:004339330.016
embryonic hemopoiesisGO:0035162530.016
stem cell differentiationGO:00488631170.016
cilium morphogenesisGO:0060271850.016
positive regulation of cellular catabolic processGO:003133130.016
cell part morphogenesisGO:00329902460.016
regulation of transmembrane transporter activityGO:002289820.016
negative regulation of macromolecule metabolic processGO:0010605760.016
regulation of cell communicationGO:00106462320.016
calcium ion dependent exocytosisGO:001715610.016
mitochondrion organizationGO:000700540.016
membrane fusionGO:006102520.016
determination of bilateral symmetryGO:00098552040.016
developmental growth involved in morphogenesisGO:0060560860.016
double strand break repairGO:000630230.016
peptidyl serine phosphorylationGO:001810510.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
positive regulation of cytokine productionGO:000181920.015
regulation of protein import into nucleusGO:004230620.015
cilium organizationGO:0044782710.015
negative regulation of cytokine productionGO:000181810.015
stem cell proliferationGO:007208940.015
cardiac atrium developmentGO:000323040.015
interspecies interaction between organismsGO:004441940.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
blood vessel developmentGO:00015682460.015
specification of symmetryGO:00097992040.015
positive regulation of catabolic processGO:000989640.015
meiotic cell cycle processGO:190304630.015
endosome organizationGO:000703220.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.015
establishment of protein localization to organelleGO:007259440.015
regulation of cell shapeGO:000836010.015
embryo development ending in birth or egg hatchingGO:00097922710.015
muscle structure developmentGO:00610611960.015
post golgi vesicle mediated transportGO:000689210.015
retina development in camera type eyeGO:00600411460.014
determination of left right symmetryGO:00073681790.014
programmed cell deathGO:00125011190.014
cell deathGO:00082191210.014
mechanosensory behaviorGO:000763820.014
regulation of autophagyGO:001050630.014
response to glucocorticoidGO:005138410.014
peptide metabolic processGO:000651810.014
retina morphogenesis in camera type eyeGO:0060042790.014
regulation of receptor activityGO:001046920.014
monoamine transportGO:001584410.014
regulation of meiotic cell cycleGO:005144510.014
response to drugGO:004249330.014
antimicrobial humoral responseGO:001973020.014
digestive tract morphogenesisGO:00485462310.014
adult behaviorGO:003053420.014
intracellular signal transductionGO:0035556850.014
digestive system developmentGO:00551232890.014
cellular component assembly involved in morphogenesisGO:00109271070.014
regulation of protein complex disassemblyGO:004324410.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
regulation of myotube differentiationGO:001083020.014
growthGO:00400071740.014
protein localization to nucleusGO:003450430.014
synaptic growth at neuromuscular junctionGO:005112420.014
positive regulation of cell divisionGO:005178120.013
cortical actin cytoskeleton organizationGO:003086610.013
g protein coupled receptor signaling pathwayGO:0007186740.013
cellular response to lipopolysaccharideGO:007122230.013
regulation of exocytosisGO:001715710.013
negative regulation of ras protein signal transductionGO:004658010.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
cellular localizationGO:0051641970.013
positive regulation of translationGO:004572710.013
cellular response to hypoxiaGO:007145610.013
protein complex disassemblyGO:004324110.013
single organism localizationGO:19025782250.013
protein polymerizationGO:005125840.013
carbon dioxide transportGO:001567030.013
mesenchyme developmentGO:00604851270.013
cellular amide metabolic processGO:004360340.013
microtubule organizing center organizationGO:003102310.013
deathGO:00162651210.013
protein homooligomerizationGO:005126030.013
establishment of synaptic vesicle localizationGO:009748010.013
regulation of organelle assemblyGO:190211540.013
cellular response to oxygen levelsGO:007145310.013
regulation of cell developmentGO:00602841000.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
regulation of gtpase activityGO:004308720.013
multi organism cellular processGO:004476420.013
regulation of epithelial cell proliferationGO:005067830.013
regulation of transporter activityGO:003240920.013
regulation of ion transmembrane transporter activityGO:003241220.012
rna 3 end processingGO:003112320.012
myeloid cell homeostasisGO:0002262560.012
regulation of blood pressureGO:000821710.012
negative regulation of cytoplasmic transportGO:190365020.012
system processGO:00030081850.012
cellular protein modification processGO:00064641000.012
nuclear importGO:005117030.012
negative regulation of intracellular transportGO:003238730.012
regulation of biomineral tissue developmentGO:007016720.012
regulation of developmental processGO:00507932470.012
cellular response to chemical stimulusGO:00708871570.012
cortical cytoskeleton organizationGO:003086510.012
axonal defasciculationGO:000741420.012
negative regulation of apoptotic processGO:0043066550.012
histone h3 k4 methylationGO:005156820.012
cellular component disassemblyGO:002241110.012
skeletal system developmentGO:00015011810.012
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.012
regulation of gtp catabolic processGO:003312420.012
protein stabilizationGO:005082120.012
cell substrate junction assemblyGO:000704420.012
developmental growthGO:00485891660.012
cellular response to radiationGO:007147840.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
i kappab kinase nf kappab signalingGO:000724940.012
positive regulation of secretionGO:005104710.012
cytoskeleton dependent cytokinesisGO:006164030.012
neuron projection developmentGO:00311751800.012
cellular response to decreased oxygen levelsGO:003629410.012
cellular component assemblyGO:00226071700.012
response to corticosteroidGO:003196010.012
adherens junction organizationGO:003433240.012
regulation of reactive oxygen species metabolic processGO:200037720.012
centrosome organizationGO:005129710.012
response to amineGO:001407510.012
specification of axis polarityGO:006500140.012
fat soluble vitamin metabolic processGO:000677540.012
positive regulation of cellular metabolic processGO:0031325940.012
positive regulation of neuron deathGO:190121610.012
regulation of erythrocyte differentiationGO:004564620.012
autophagyGO:000691440.012
macromolecular complex disassemblyGO:003298410.012
positive regulation of nucleotide catabolic processGO:003081310.011
protein polyubiquitinationGO:000020940.011
camera type eye morphogenesisGO:00485931080.011
negative regulation of cell deathGO:0060548600.011
positive regulation of myeloid cell differentiationGO:004563920.011
actin filament based movementGO:003004810.011
regulation of cell activationGO:005086510.011
regulation of cell matrix adhesionGO:000195210.011
negative regulation of secretion by cellGO:190353120.011
regulation of programmed cell deathGO:00430671010.011
g2 m transition of mitotic cell cycleGO:000008640.011
muscle organ developmentGO:00075171010.011
hepaticobiliary system developmentGO:0061008980.011
protein secretionGO:000930610.011
regulation of rho protein signal transductionGO:003502320.011
negative regulation of cellular catabolic processGO:003133030.011
cell morphogenesis involved in differentiationGO:00009041950.011
production of molecular mediator of immune responseGO:000244020.011
oocyte maturationGO:000155640.011
response to organic substanceGO:00100331530.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
negative regulation of defense responseGO:003134820.011
cell cycle g2 m phase transitionGO:004483940.011
response to woundingGO:00096111160.011
actin polymerization or depolymerizationGO:000815420.011
muscle tissue developmentGO:00605371100.011
single organism membrane fusionGO:004480120.011
striated muscle tissue developmentGO:00147061100.011
locomotionGO:00400113130.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
single organism nuclear importGO:190259330.011
determination of heart left right asymmetryGO:00613711170.011
leukocyte proliferationGO:007066110.011
protein depolymerizationGO:005126110.011
regulation of anatomical structure morphogenesisGO:00226031300.011
positive regulation of map kinase activityGO:004340630.011
epithelial tube morphogenesisGO:00605621480.011
axon developmentGO:00615641660.011
cellular carbohydrate metabolic processGO:004426240.011
response to amphetamineGO:000197510.011
intracellular mrna localizationGO:000829810.011
regulation of protein localization to nucleusGO:190018020.011
regulation of endocrine processGO:004406020.011
response to uvGO:000941130.011
regenerationGO:0031099910.011
positive regulation of chromatin modificationGO:190331010.010
angiogenesisGO:00015251580.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.010
embryonic heart tube morphogenesisGO:00031431080.010
response to external stimulusGO:00096052640.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
positive regulation of immune effector processGO:000269930.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
neuron projection morphogenesisGO:00488121610.010
cell cycle g1 s phase transitionGO:004484310.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
regulation of erk1 and erk2 cascadeGO:007037240.010
actin filament polymerizationGO:003004120.010
neuroblast proliferationGO:000740520.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
striated muscle cell differentiationGO:00511461290.010
negative regulation of nucleobase containing compound metabolic processGO:0045934590.010
viral processGO:001603210.010
phototransductionGO:000760220.010
protein import into nucleusGO:000660630.010
convergent extensionGO:00600261180.010
dicarboxylic acid transportGO:000683510.010
nephron tubule morphogenesisGO:007207810.010
ovulation cycleGO:004269820.010

chd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
musculoskeletal system diseaseDOID:1700.021
muscular diseaseDOID:008000000.021
immune system diseaseDOID:291400.019
myopathyDOID:42300.017
muscle tissue diseaseDOID:6600.017
nervous system diseaseDOID:86300.016
cardiovascular system diseaseDOID:128700.015
disease of metabolismDOID:001466700.013
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
hematopoietic system diseaseDOID:7400.010