Danio rerio

0 known processes

lrrtm1

leucine rich repeat transmembrane neuronal 1

(Aliases: im:6904481,FLJ12568)

lrrtm1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.405
larval developmentGO:000216420.338
regulation of developmental processGO:00507932470.266
lymphatic endothelial cell fate commitmentGO:006083810.212
cellular protein modification processGO:00064641000.177
nucleic acid metabolic processGO:00903042440.166
synaptic transmissionGO:0007268350.157
Mouse
neuron differentiationGO:00301823530.156
cell projection organizationGO:00300302840.153
regionalizationGO:00030022740.152
branching morphogenesis of a nerveGO:004875540.150
positive regulation of cellular processGO:00485222010.150
Mouse
regulation of biological qualityGO:00650082630.140
Mouse
heterocycle metabolic processGO:00464832900.137
maintenance of locationGO:005123540.127
cell fate commitmentGO:0045165990.127
locomotionGO:00400113130.125
positive regulation of biological processGO:00485182530.122
Mouse
generation of neuronsGO:00486993850.115
embryonic organ morphogenesisGO:00485622740.114
cellular macromolecule metabolic processGO:00442603910.113
Mouse
cellular protein metabolic processGO:00442671290.106
olfactory lobe developmentGO:002198840.104
regulation of cellular amine metabolic processGO:003323800.099
rna biosynthetic processGO:00327741810.099
negative regulation of cellular processGO:00485232830.090
Mouse
regulation of multicellular organismal developmentGO:20000262230.083
mesenchyme developmentGO:00604851270.082
cellular nitrogen compound metabolic processGO:00346412900.081
chordate embryonic developmentGO:00430092710.080
negative regulation of kinase activityGO:003367340.080
multicellular organism growthGO:003526440.079
nitrogen compound metabolic processGO:00068073190.077
regulation of signalingGO:00230512350.075
Mouse
protein metabolic processGO:00195381830.074
macromolecule modificationGO:00434121110.073
cell proliferation in forebrainGO:002184630.073
negative regulation of protein kinase activityGO:000646940.071
cell morphogenesis involved in differentiationGO:00009041950.069
neuron neuron synaptic transmissionGO:000727010.067
protein modification processGO:00362111000.067
skeletal system developmentGO:00015011810.067
morphogenesis of an epitheliumGO:00020093330.066
head developmentGO:00603223030.066
cellular component morphogenesisGO:00329893360.066
nucleic acid templated transcriptionGO:00976591810.066
homeostatic processGO:00425921420.065
striated muscle tissue developmentGO:00147061100.065
brain morphogenesisGO:0048854180.065
neuron projection morphogenesisGO:00488121610.063
regulation of transcription dna templatedGO:00063552130.062
aromatic compound biosynthetic processGO:00194382170.062
phosphate containing compound metabolic processGO:00067961080.061
positive regulation of canonical wnt signaling pathwayGO:009026340.060
regulation of biosynthetic processGO:00098892500.059
regulation of cell communicationGO:00106462320.058
Mouse
regulation of peptidyl tyrosine phosphorylationGO:005073010.058
negative regulation of axon guidanceGO:190266810.057
neural crest cell differentiationGO:0014033720.057
cell cell recognitionGO:000998810.057
stem cell developmentGO:0048864820.056
circadian regulation of gene expressionGO:003292280.056
positive regulation of cell cycleGO:004578730.055
negative regulation of axon extension involved in axon guidanceGO:004884310.053
mesenchymal cell differentiationGO:0048762870.053
regulation of macromolecule metabolic processGO:00602553170.052
Mouse
cognitionGO:005089010.051
response to chemicalGO:00422213200.050
endodermal cell fate determinationGO:000749320.050
cell cycleGO:0007049930.050
cellular biosynthetic processGO:00442492860.050
negative regulation of protein phosphorylationGO:000193340.049
nucleobase containing compound metabolic processGO:00061392740.049
brain developmentGO:00074202930.048
camera type eye developmentGO:00430102220.048
regulation of cellular metabolic processGO:00313233200.048
Mouse
sensory organ developmentGO:00074233930.047
stem cell differentiationGO:00488631170.047
localization of cellGO:00516742440.047
meiotic nuclear divisionGO:000712640.046
positive regulation of cell divisionGO:005178120.046
cell migrationGO:00164772370.045
regulation of multicellular organismal processGO:00512392770.044
regulation of cell differentiationGO:00455951420.044
regulation of cellular ketone metabolic processGO:001056570.044
muscle structure developmentGO:00610611960.044
transcription dna templatedGO:00063511810.044
regulation of bindingGO:005109830.043
regulation of response to stimulusGO:00485832690.043
negative regulation of nuclear divisionGO:005178430.043
regulation of multicellular organism growthGO:004001440.043
neural tube formationGO:0001841160.043
regulation of primary metabolic processGO:00800903110.043
phagocytosisGO:000690930.042
ameboidal type cell migrationGO:00016671430.042
organic cyclic compound metabolic processGO:19013603010.042
cell cell signalingGO:0007267520.042
Mouse
lipid storageGO:001991510.042
organic substance biosynthetic processGO:19015762890.042
neural crest cell developmentGO:0014032620.042
cell morphogenesisGO:00009022890.041
thermosensory behaviorGO:004004010.041
heart developmentGO:00075073130.041
post embryonic organ developmentGO:004856940.040
cerebellar granular layer developmentGO:002168130.040
forebrain developmentGO:0030900960.040
organic acid metabolic processGO:0006082310.040
erk1 and erk2 cascadeGO:007037140.039
regulation of transcription from rna polymerase ii promoterGO:00063571140.039
agingGO:000756820.038
regulation of anatomical structure sizeGO:0090066330.038
peptide transportGO:001583310.037
dopaminergic neuron differentiationGO:0071542140.037
wnt signaling pathwayGO:0016055800.036
regulation of nervous system developmentGO:0051960900.036
mesenchymal cell developmentGO:0014031780.035
small molecule metabolic processGO:0044281770.035
circulatory system processGO:0003013870.035
neuron projection developmentGO:00311751800.035
regulation of cellular amino acid metabolic processGO:000652100.034
cell adhesionGO:0007155400.034
carbohydrate homeostasisGO:003350010.034
cellular ketone metabolic processGO:0042180110.034
single organism metabolic processGO:00447102170.034
Mouse
mitotic cell cycle processGO:1903047480.034
regulation of cell sizeGO:0008361290.034
cell proliferationGO:0008283800.034
regulation of erk1 and erk2 cascadeGO:007037240.034
neuron developmentGO:00486662620.033
central nervous system neuron developmentGO:0021954290.033
regulation of rna metabolic processGO:00512522240.033
response to abiotic stimulusGO:00096281220.033
muscle tissue developmentGO:00605371100.033
response to hexoseGO:000974630.033
protein secretionGO:000930610.033
regulation of protein bindingGO:004339330.032
regulation of locomotionGO:0040012550.032
cell divisionGO:0051301200.032
phosphorus metabolic processGO:00067931090.032
hindbrain formationGO:002157630.032
regulation of transcription from rna polymerase iii promoterGO:000635910.032
phagocytosis engulfmentGO:000691110.031
regulation of molecular functionGO:0065009700.031
embryo development ending in birth or egg hatchingGO:00097922710.031
carboxylic acid metabolic processGO:0019752220.031
positive regulation of erk1 and erk2 cascadeGO:007037420.030
regulation of protein modification by small protein conjugation or removalGO:190332030.030
heterocycle biosynthetic processGO:00181302150.030
negative chemotaxisGO:005091910.030
axon ensheathment in central nervous systemGO:003229120.030
vasculature developmentGO:00019442780.030
ectodermal placode developmentGO:0071696370.030
negative regulation of biological processGO:00485193040.030
Mouse
negative regulation of epithelial cell migrationGO:001063310.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
cell cycle processGO:0022402530.029
neurological system processGO:0050877620.029
regulation of cell cycleGO:0051726520.029
endodermal digestive tract morphogenesisGO:006103120.029
oxoacid metabolic processGO:0043436310.029
regulation of dendrite morphogenesisGO:004881430.029
regulation of circadian rhythmGO:004275240.029
response to glucoseGO:000974930.028
response to drugGO:004249330.028
regulation of gene expressionGO:00104682650.028
cellular component movementGO:00069283350.028
negative regulation of mitosisGO:004583930.028
regulation of metabolic processGO:00192223590.028
Mouse
system processGO:00030081850.027
negative regulation of multicellular organismal processGO:0051241690.027
positive regulation of catabolic processGO:000989640.027
midbrain developmentGO:0030901280.027
regulation of cellular component organizationGO:0051128860.027
Mouse
chemosensory behaviorGO:000763510.027
neuroblast proliferationGO:000740520.026
guanosine containing compound catabolic processGO:190106920.026
regulation of intracellular protein transportGO:003315730.026
spinal cord developmentGO:0021510460.026
regulation of establishment of protein localizationGO:007020140.026
behaviorGO:0007610740.026
Mouse
regulation of dendrite developmentGO:005077330.025
blood circulationGO:0008015870.025
enzyme linked receptor protein signaling pathwayGO:00071671060.025
reproductionGO:0000003400.025
regulation of phospholipase c activityGO:190027410.025
diencephalon developmentGO:0021536580.025
cellular response to external stimulusGO:007149620.025
rna metabolic processGO:00160702190.025
positive regulation of biosynthetic processGO:0009891680.025
tube morphogenesisGO:00352393490.025
gland developmentGO:00487321430.024
cellular monovalent inorganic cation homeostasisGO:003000420.024
cellular aromatic compound metabolic processGO:00067252950.024
neural precursor cell proliferationGO:0061351200.024
olfactory bulb developmentGO:002177240.024
response to carbohydrateGO:000974330.024
organic cyclic compound biosynthetic processGO:19013622230.024
cell migration involved in heart formationGO:0060974100.024
transportGO:00068102200.024
Mouse
water homeostasisGO:003010440.024
chemotaxisGO:00069351040.024
gtp metabolic processGO:004603940.024
amine metabolic processGO:000930820.023
embryonic skeletal system morphogenesisGO:0048704930.023
regenerationGO:0031099910.023
single organism transportGO:00447652060.023
Mouse
adherens junction organizationGO:003433240.023
organonitrogen compound metabolic processGO:1901564740.023
regulation of synaptic plasticityGO:004816710.023
Mouse
regulation of phospholipase activityGO:001051720.023
adult behaviorGO:003053420.023
regulation of cellular biosynthetic processGO:00313262450.023
cardiac cell fate commitmentGO:006091110.023
axon midline choice point recognitionGO:001619940.023
membrane fusionGO:006102520.023
negative regulation of neuron projection regenerationGO:007057140.022
cell substrate adhesionGO:003158940.022
digestive system developmentGO:00551232890.022
heart processGO:0003015710.022
blood vessel morphogenesisGO:00485142160.022
positive regulation of transportGO:005105020.022
glucose homeostasisGO:004259310.022
cell morphogenesis involved in neuron differentiationGO:00486671630.022
negative regulation of epithelial cell proliferationGO:005068010.022
cellular amine metabolic processGO:004410620.022
negative regulation of macromolecule metabolic processGO:0010605760.021
Mouse
skeletal muscle organ developmentGO:0060538780.021
positive regulation of gene expressionGO:0010628710.021
cellular amino acid metabolic processGO:000652070.021
positive regulation of lipase activityGO:006019310.021
nuclear divisionGO:0000280230.021
sex determinationGO:000753010.021
alternative mrna splicing via spliceosomeGO:000038010.021
positive regulation of metabolic processGO:00098931080.021
gene expressionGO:00104672520.020
response to woundingGO:00096111160.020
nuclear transportGO:005116940.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
signal transductionGO:00071654550.020
peptidyl serine phosphorylationGO:001810510.020
macromolecule biosynthetic processGO:00090592270.020
b cell activationGO:004211320.020
astrocyte differentiationGO:004870810.020
posterior lateral line system developmentGO:0048915460.020
negative regulation of chemotaxisGO:005092240.020
olfactory placode developmentGO:0071698120.019
cell projection morphogenesisGO:00488582440.019
cartilage developmentGO:0051216960.019
positive regulation of secretion by cellGO:190353210.019
liver developmentGO:0001889960.019
camera type eye morphogenesisGO:00485931080.019
regulation of cell shapeGO:000836010.019
neural retina developmentGO:0003407490.019
cytokinesisGO:000091030.019
cytoskeleton dependent cytokinesisGO:006164030.019
taxisGO:00423301090.019
determination of heart left right asymmetryGO:00613711170.019
skeletal muscle tissue developmentGO:0007519670.019
skeletal system morphogenesisGO:00487051020.019
response to stressGO:00069502630.019
anterior posterior pattern specificationGO:00099521520.019
regulation of wnt signaling pathwayGO:0030111530.019
response to light stimulusGO:0009416460.019
neural tube patterningGO:0021532330.018
regulation of cell projection organizationGO:0031344440.018
growthGO:00400071740.018
positive regulation of cellular catabolic processGO:003133130.018
regulation of cell motilityGO:2000145460.018
membrane invaginationGO:001032410.018
neural crest formationGO:0014029140.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
regulation of receptor internalizationGO:000209020.018
Mouse
response to monosaccharideGO:003428430.018
synaptic target recognitionGO:000803910.018
positive regulation of nucleobase containing compound metabolic processGO:0045935690.018
immune system developmentGO:00025201910.017
developmental growthGO:00485891660.017
regulation of synapse organizationGO:005080730.017
positive regulation of macromolecule metabolic processGO:0010604930.017
action potentialGO:0001508190.017
modification dependent macromolecule catabolic processGO:004363230.017
dendrite guidanceGO:007098300.017
blood vessel developmentGO:00015682460.017
protein phosphorylationGO:0006468470.017
regulation of mrna processingGO:005068430.017
cellular component biogenesisGO:00440851780.017
regulation of cellular component movementGO:0051270550.017
embryonic organ developmentGO:00485683810.017
regulation of sodium ion transportGO:000202820.016
extracellular structure organizationGO:0043062270.016
positive regulation of mrna metabolic processGO:190331320.016
cell proliferation in midbrainGO:003327840.016
regulation of glial cell differentiationGO:004568540.016
mitotic cell cycleGO:0000278640.016
limbic system developmentGO:0021761160.016
eye developmentGO:00016542770.016
multi organism processGO:00517041340.016
phosphorylationGO:0016310690.016
regulation of dna templated transcription in response to stressGO:004362000.016
nucleocytoplasmic transportGO:000691340.016
regulation of cell activationGO:005086510.016
regulation of cell cycle processGO:0010564200.016
cellular macromolecule biosynthetic processGO:00346452240.016
neural tube developmentGO:0021915620.016
retina development in camera type eyeGO:00600411460.016
nucleobase containing compound biosynthetic processGO:00346542050.016
biosynthetic processGO:00090582940.016
immune system processGO:00023762410.016
cell proliferation in hindbrainGO:002153440.016
locomotor rhythmGO:004547530.016
regulation of cytoplasmic transportGO:190364940.016
cellular response to radiationGO:007147840.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
regulation of nucleocytoplasmic transportGO:004682220.016
peptidyl serine modificationGO:001820920.015
negative regulation of response to stimulusGO:00485851040.015
lateral line developmentGO:0048882660.015
regulation of anatomical structure morphogenesisGO:00226031300.015
ovulation cycle processGO:002260220.015
regulation of alternative mrna splicing via spliceosomeGO:000038110.015
regulation of neurogenesisGO:0050767870.015
photoreceptor cell differentiationGO:0046530550.015
atp catabolic processGO:000620040.015
regulation of nitrogen compound metabolic processGO:00511712510.015
nuclear exportGO:005116810.015
regulation of purine nucleotide catabolic processGO:003312120.015
neuromuscular process controlling balanceGO:005088530.014
glial cell proliferationGO:001400940.014
angioblast cell migration involved in selective angioblast sproutingGO:003547540.014
positive regulation of translationGO:004572710.014
establishment of synaptic vesicle localizationGO:009748010.014
mesoderm developmentGO:0007498880.014
cellular response to oxygen levelsGO:007145310.014
meiotic cell cycle processGO:190304630.014
lateral mesoderm developmentGO:0048368230.014
regulation of protein targetingGO:190353320.014
negative regulation of neuron projection developmentGO:001097790.014
inositol lipid mediated signalingGO:004801720.014
regulation of hormone secretionGO:004688320.014
regulation of metal ion transportGO:001095940.014
intracellular signal transductionGO:0035556850.014
regulation of protein transportGO:005122330.014
negative regulation of intracellular transportGO:003238730.014
positive regulation of cellular amine metabolic processGO:003324000.014
negative regulation of axon extensionGO:003051770.014
hepaticobiliary system developmentGO:0061008980.014
positive regulation of rna biosynthetic processGO:1902680570.014
fin regenerationGO:0031101510.014
mitotic dna damage checkpointGO:004477340.014
negative regulation of cell deathGO:0060548600.014
cell migration involved in vasculogenesisGO:003544110.014
regulation of oligodendrocyte differentiationGO:004871310.014
guanosine containing compound metabolic processGO:190106840.014
central nervous system neuron axonogenesisGO:0021955180.014
phosphatidylinositol mediated signalingGO:004801520.013
negative regulation of cell morphogenesis involved in differentiationGO:001077180.013
positive regulation of nucleic acid templated transcriptionGO:1903508570.013
negative regulation of catalytic activityGO:0043086210.013
cellular response to stressGO:0033554620.013
regulation of organ morphogenesisGO:2000027350.013
olfactory placode morphogenesisGO:007169970.013
cranial nerve morphogenesisGO:0021602150.013
organelle fissionGO:0048285230.013
oocyte maturationGO:000155640.013
positive regulation of developmental processGO:0051094500.013
endothelial cell fate commitmentGO:006083930.013
melanin metabolic processGO:000658220.013
synaptic vesicle localizationGO:009747910.013
cell surface receptor signaling pathwayGO:00071663250.013
negative regulation of intracellular protein transportGO:009031730.013
regulation of gtp catabolic processGO:003312420.013
regulation of axon extensionGO:0030516240.013
cell cycle g1 s phase transitionGO:004484310.013
negative regulation of signalingGO:0023057960.013
embryonic skeletal system developmentGO:0048706970.013
axis specificationGO:0009798430.013
outflow tract morphogenesisGO:000315110.013
proteasomal protein catabolic processGO:001049820.013
regulation of rna biosynthetic processGO:20011412130.013
synaptic vesicle recyclingGO:003646510.013
otic vesicle morphogenesisGO:0071600340.012
fin developmentGO:0033333770.012
positive regulation of secretionGO:005104710.012
heart morphogenesisGO:00030071560.012
positive regulation of chromosome organizationGO:200125210.012
positive regulation of cytoskeleton organizationGO:005149530.012
regulation of localizationGO:00328791040.012
Mouse
lymphatic endothelial cell differentiationGO:006083610.012
cellular response to hypoxiaGO:007145610.012
cell cycle arrestGO:000705010.012
mrna metabolic processGO:0016071200.012
positive regulation of muscle organ developmentGO:004863610.012
sensory organ morphogenesisGO:00905962000.012
negative regulation of catabolic processGO:000989530.012
negative regulation of locomotionGO:0040013180.012
regulation of phosphate metabolic processGO:0019220430.012
photoreceptor cell fate commitmentGO:004655210.012
regulation of neurotransmitter transportGO:005158810.012
cell migration involved in gastrulationGO:0042074790.012
regulation of reproductive processGO:200024140.012
positive regulation of cellular biosynthetic processGO:0031328680.012
regulation of blood pressureGO:000821710.012
multicellular organismal reproductive processGO:0048609350.012
positive regulation of cell communicationGO:0010647560.012
Mouse
response to external stimulusGO:00096052640.012
mrna processingGO:0006397140.012
g1 s transition of mitotic cell cycleGO:000008210.012
positive regulation of cellular component biogenesisGO:004408930.012
protein targeting to membraneGO:000661210.012
ectodermal placode morphogenesisGO:0071697320.012
response to radiationGO:0009314510.011
embryonic skeletal joint developmentGO:007249830.011
neuronal action potentialGO:0019228180.011
regulation of synapse assemblyGO:005196330.011
transcription from rna polymerase ii promoterGO:0006366800.011
positive regulation of rna metabolic processGO:0051254590.011
negative regulation of cell growthGO:003030870.011
gtp catabolic processGO:000618420.011
biological adhesionGO:0022610400.011
stem cell divisionGO:001714510.011
fertilizationGO:000956630.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
developmental programmed cell deathGO:001062340.011
organelle organizationGO:00069962270.011
anterior commissure morphogenesisGO:002196030.011
response to metal ionGO:0010038340.011
synaptic transmission cholinergicGO:000727140.011
sulfur compound metabolic processGO:0006790130.011
determination of bilateral symmetryGO:00098552040.011
retinal cell programmed cell deathGO:004666620.011
negative regulation of multi organism processGO:004390130.011
regulation of growthGO:0040008420.011
cranial nerve formationGO:0021603130.011
stem cell proliferationGO:007208940.011
negative regulation of gliogenesisGO:001401410.011
negative regulation of cell migrationGO:0030336170.011
central nervous system projection neuron axonogenesisGO:0021952150.011
forebrain neuron developmentGO:002188470.011
positive regulation of map kinase activityGO:004340630.011
muscle organ developmentGO:00075171010.011
regulation of cell morphogenesisGO:0022604420.011
cellular component assemblyGO:00226071700.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
hormone transportGO:000991420.011
negative regulation of cell projection organizationGO:003134590.011
connective tissue developmentGO:0061448990.010
cell part morphogenesisGO:00329902460.010
positive regulation of cell activationGO:005086710.010
transcription from rna polymerase iii promoterGO:000638310.010
regulation of cell proliferationGO:0042127370.010
regulation of kinase activityGO:0043549150.010
convergent extensionGO:00600261180.010
cell motilityGO:00488702440.010
entrainment of circadian clockGO:000964920.010
negative regulation of cellular component movementGO:0051271180.010
negative regulation of neuron differentiationGO:0045665100.010
regulation of protein ubiquitinationGO:003139630.010
regulation of behaviorGO:0050795240.010
positive regulation of macromolecule biosynthetic processGO:0010557590.010
reproductive processGO:0022414400.010
regulation of intracellular signal transductionGO:1902531570.010
specification of axis polarityGO:006500140.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010

lrrtm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
nervous system diseaseDOID:86300.056
musculoskeletal system diseaseDOID:1700.023
bone diseaseDOID:008000100.023
bone development diseaseDOID:008000600.023
connective tissue diseaseDOID:6500.023
idiopathic generalized epilepsyDOID:182700.014
central nervous system diseaseDOID:33100.014
brain diseaseDOID:93600.014
epilepsy syndromeDOID:182600.014
dysostosisDOID:193400.012
synostosisDOID:1197100.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
disease of metabolismDOID:001466700.011
organ system cancerDOID:005068600.010