Danio rerio

0 known processes

ppl

periplakin

(Aliases: im:7149519,cb180,sb:cb180,im:7140067)

ppl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
desmosome organizationGO:000293430.277
growthGO:00400071740.236
regulation of water loss via skinGO:003356110.219
keratinocyte differentiationGO:003021600.159
morphogenesis of an epitheliumGO:00020093330.152
gastrulation with mouth forming secondGO:0001702440.139
regulation of biological qualityGO:00650082630.128
neuron developmentGO:00486662620.120
fin regenerationGO:0031101510.119
hemopoiesisGO:00300971830.113
convergent extensionGO:00600261180.107
system processGO:00030081850.099
transportGO:00068102200.097
inner ear receptor stereocilium organizationGO:006012280.085
regulation of metabolic processGO:00192223590.080
gene expressionGO:00104672520.077
immune system processGO:00023762410.075
organelle organizationGO:00069962270.072
tube morphogenesisGO:00352393490.071
regulation of gene expressionGO:00104682650.068
actomyosin structure organizationGO:0031032530.068
immune system developmentGO:00025201910.066
organic acid metabolic processGO:0006082310.065
cellular macromolecule metabolic processGO:00442603910.065
hematopoietic or lymphoid organ developmentGO:00485341910.062
positive regulation of cell cycleGO:004578730.062
regulation of macromolecule metabolic processGO:00602553170.060
wound healingGO:0042060900.059
regulation of inflammatory responseGO:005072720.057
regulation of establishment of protein localizationGO:007020140.056
developmental growthGO:00485891660.054
gastrulationGO:00073692080.053
regulation of epithelial cell proliferationGO:005067830.053
epidermal cell differentiationGO:0009913360.051
regulation of multicellular organismal processGO:00512392770.051
positive regulation of transportGO:005105020.050
multicellular organismal water homeostasisGO:005089110.049
regenerationGO:0031099910.048
single organism organelle organizationGO:19025891990.047
striated muscle cell differentiationGO:00511461290.046
oxoacid metabolic processGO:0043436310.045
response to corticosteroidGO:003196010.044
stem cell maintenanceGO:001982740.043
positive regulation of cellular processGO:00485222010.043
epithelial cell differentiationGO:00308551160.041
response to stressGO:00069502630.041
muscle cell differentiationGO:00426921390.040
cellular protein metabolic processGO:00442671290.039
single organism transportGO:00447652060.039
regulation of nitrogen compound metabolic processGO:00511712510.038
cellular component morphogenesisGO:00329893360.038
nucleic acid metabolic processGO:00903042440.036
protein secretionGO:000930610.036
multi organism processGO:00517041340.036
regulation of localizationGO:00328791040.035
negative regulation of cytokine productionGO:000181810.035
tissue regenerationGO:0042246740.034
regulation of cellular metabolic processGO:00313233200.033
regulation of cytokine productionGO:000181730.032
negative regulation of protein transportGO:005122430.032
cytoskeleton organizationGO:0007010960.031
heart loopingGO:0001947940.031
cellular component movementGO:00069283350.031
protein metabolic processGO:00195381830.031
behaviorGO:0007610740.030
generation of neuronsGO:00486993850.030
single organism localizationGO:19025782250.030
regulation of metal ion transportGO:001095940.030
cellular response to extracellular stimulusGO:003166820.030
negative regulation of epithelial cell proliferationGO:005068010.030
alpha amino acid metabolic processGO:190160530.030
kupffer s vesicle developmentGO:0070121500.029
fatty acid biosynthetic processGO:000663340.029
phagocytosisGO:000690930.029
anion transportGO:0006820380.029
complement activationGO:000695630.028
protein activation cascadeGO:007237660.028
homeostatic processGO:00425921420.028
striated muscle cell developmentGO:00550021080.028
cell deathGO:00082191210.027
cellular component assemblyGO:00226071700.027
muscle cell developmentGO:00550011150.026
establishment of localizationGO:00512342440.026
muscle structure developmentGO:00610611960.026
erythrocyte maturationGO:004324980.026
epiboly involved in gastrulation with mouth forming secondGO:0055113350.026
phagocytosis engulfmentGO:000691110.025
extrinsic apoptotic signaling pathwayGO:009719130.025
cell morphogenesisGO:00009022890.025
regulation of primary metabolic processGO:00800903110.025
synaptic growth at neuromuscular junctionGO:005112420.024
cell projection organizationGO:00300302840.024
nitrogen compound metabolic processGO:00068073190.024
myofibril assemblyGO:0030239480.024
heart developmentGO:00075073130.024
cellular nitrogen compound metabolic processGO:00346412900.024
agingGO:000756820.023
regulation of epidermis developmentGO:004568220.023
female sex differentiationGO:004666040.023
autophagyGO:000691440.023
mesenchyme developmentGO:00604851270.023
sensory organ developmentGO:00074233930.023
liver developmentGO:0001889960.022
response to endogenous stimulusGO:0009719830.022
positive regulation of biological processGO:00485182530.022
cell projection morphogenesisGO:00488582440.022
regulation of sodium ion transportGO:000202820.022
cellular response to starvationGO:000926710.022
medial fin developmentGO:0033338160.022
response to fluid shear stressGO:003440520.022
positive regulation of cell deathGO:0010942290.022
negative regulation of cellular processGO:00485232830.021
signal transductionGO:00071654550.021
response to woundingGO:00096111160.021
regulation of cellular macromolecule biosynthetic processGO:20001122220.021
protein modification processGO:00362111000.021
adherens junction organizationGO:003433240.021
desmosome assemblyGO:000215920.021
single organism membrane fusionGO:004480120.021
water homeostasisGO:003010440.021
skin developmentGO:0043588540.020
aromatic compound biosynthetic processGO:00194382170.020
regulation of cell motilityGO:2000145460.020
cardiac conductionGO:006133730.020
calcium independent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633810.020
response to glucocorticoidGO:005138410.020
digestive tract developmentGO:00485652650.020
plasma membrane repairGO:000177820.020
regulation of cellular biosynthetic processGO:00313262450.020
cell proliferationGO:0008283800.019
cellular response to external stimulusGO:007149620.019
deathGO:00162651210.019
determination of left right symmetryGO:00073681790.019
regulation of nervous system developmentGO:0051960900.019
fatty acid transportGO:001590810.019
neural crest cell differentiationGO:0014033720.019
long chain fatty acid transportGO:001590910.019
regulation of eye photoreceptor cell developmentGO:004247820.019
cell cycle g1 s phase transitionGO:004484310.019
digestive tract morphogenesisGO:00485462310.019
organelle fusionGO:004828430.019
rna metabolic processGO:00160702190.019
regulation of cellular component movementGO:0051270550.018
response to organic substanceGO:00100331530.018
regulation of locomotionGO:0040012550.018
negative regulation of defense responseGO:003134820.018
neuron differentiationGO:00301823530.018
cell surface receptor signaling pathwayGO:00071663250.018
apoptotic processGO:00069151160.018
actin filament based movementGO:003004810.018
morphogenesis of an epithelial sheetGO:0002011490.017
response to abiotic stimulusGO:00096281220.017
negative regulation of secretion by cellGO:190353120.017
g1 s transition of mitotic cell cycleGO:000008210.017
membrane invaginationGO:001032410.017
embryonic organ developmentGO:00485683810.016
cellular macromolecule biosynthetic processGO:00346452240.016
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.016
cognitionGO:005089010.016
stem cell differentiationGO:00488631170.016
locomotionGO:00400113130.016
regulation of protein transportGO:005122330.016
establishment of endothelial barrierGO:006102830.016
reproductive processGO:0022414400.016
tissue remodelingGO:004877140.016
positive regulation of macromolecule metabolic processGO:0010604930.015
neuroblast differentiationGO:001401610.015
regulation of dna templated transcription in response to stressGO:004362000.015
heterocycle metabolic processGO:00464832900.015
cell morphogenesis involved in differentiationGO:00009041950.015
epidermis developmentGO:0008544480.015
negative regulation of response to stimulusGO:00485851040.015
glomerulus developmentGO:0032835270.015
dna templated transcription elongationGO:000635430.015
cardiac muscle tissue developmentGO:0048738480.015
regulation of cardiac muscle contractionGO:005511720.014
response to external stimulusGO:00096052640.014
regulation of cell differentiationGO:00455951420.014
response to lipidGO:0033993600.014
membrane fusionGO:006102520.014
cellular aromatic compound metabolic processGO:00067252950.014
regulation of rna metabolic processGO:00512522240.014
cellular component biogenesisGO:00440851780.014
rna biosynthetic processGO:00327741810.014
regulation of response to external stimulusGO:0032101310.014
cellular response to organic cyclic compoundGO:0071407380.013
small molecule metabolic processGO:0044281770.013
regulation of cell activationGO:005086510.013
regulation of muscle contractionGO:000693730.013
regulation of cellular ketone metabolic processGO:001056570.013
response to organic cyclic compoundGO:0014070510.013
morphogenesis of an epithelial foldGO:006057110.013
cell cell adhesion involved in gastrulationGO:007058640.013
cellular component assembly involved in morphogenesisGO:00109271070.013
embryo development ending in birth or egg hatchingGO:00097922710.013
fin developmentGO:0033333770.013
response to uvGO:000941130.013
myeloid cell homeostasisGO:0002262560.013
positive regulation of cellular component biogenesisGO:004408930.013
positive regulation of cellular metabolic processGO:0031325940.013
lateral line system developmentGO:0048925760.012
heart processGO:0003015710.012
positive regulation of secretion by cellGO:190353210.012
regulation of nucleic acid templated transcriptionGO:19035062130.012
cellular localizationGO:0051641970.012
single organism metabolic processGO:00447102170.012
skeletal system developmentGO:00015011810.012
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.012
establishment of skin barrierGO:006143610.012
action potentialGO:0001508190.012
negative regulation of secretionGO:005104820.012
cellular biosynthetic processGO:00442492860.012
multicellular organismal signalingGO:0035637220.012
monoamine transportGO:001584410.012
hatchingGO:003518840.012
heterocycle biosynthetic processGO:00181302150.012
actin mediated cell contractionGO:007025210.012
organic cyclic compound metabolic processGO:19013603010.012
cardiac cell fate commitmentGO:006091110.012
epithelial tube morphogenesisGO:00605621480.012
intestinal absorptionGO:005089220.012
stem cell developmentGO:0048864820.011
biosynthetic processGO:00090582940.011
negative regulation of wnt signaling pathway involved in heart developmentGO:000330820.011
regulation of macromolecule biosynthetic processGO:00105562250.011
cellular response to chemical stimulusGO:00708871570.011
negative regulation of biological processGO:00485193040.011
neuroblast fate commitmentGO:001401710.011
regulation of striated muscle contractionGO:000694220.011
cation transportGO:0006812810.011
regulation of ectoderm developmentGO:200038320.011
regulation of biosynthetic processGO:00098892500.011
regulation of organelle organizationGO:0033043290.011
cell motilityGO:00488702440.011
wnt signaling pathwayGO:0016055800.011
regulation of dna templated transcription elongationGO:003278430.011
regulation of rna biosynthetic processGO:20011412130.011
cell cycleGO:0007049930.011
transcription from rna polymerase ii promoterGO:0006366800.011
actin cytoskeleton organizationGO:0030036630.011
macromolecule modificationGO:00434121110.011
single fertilizationGO:000733830.011
multicellular organism growthGO:003526440.010
ectodermal cell fate specificationGO:000171520.010
cellular nitrogen compound biosynthetic processGO:00442712180.010
regulation of cell deathGO:00109411030.010
cellular protein modification processGO:00064641000.010
neural crest cell developmentGO:0014032620.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010
regulation of response to stimulusGO:00485832690.010
embryonic skeletal system developmentGO:0048706970.010
regulation of epithelial to mesenchymal transitionGO:001071730.010
cellular ketone metabolic processGO:0042180110.010
positive regulation of dna templated transcription elongationGO:003278610.010
cartilage developmentGO:0051216960.010
determination of heart left right asymmetryGO:00613711170.010

ppl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:6600.082
cardiovascular system diseaseDOID:128700.082
cardiomyopathyDOID:005070000.082
heart diseaseDOID:11400.082
disease of anatomical entityDOID:700.082
musculoskeletal system diseaseDOID:1700.082
myopathyDOID:42300.082
muscular diseaseDOID:008000000.082
intrinsic cardiomyopathyDOID:006003600.055
integumentary system diseaseDOID:1600.038