Danio rerio

66 known processes

mitfb

microphthalmia-associated transcription factor b

mitfb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular pigmentationGO:0033059300.501
pigmentationGO:0043473850.396
developmental pigmentationGO:0048066480.309
melanocyte differentiationGO:0030318260.173
neuroepithelial cell differentiationGO:0060563260.151
pigment granule localizationGO:0051875250.111
columnar cuboidal epithelial cell differentiationGO:0002065380.098
chordate embryonic developmentGO:00430092710.081
establishment of pigment granule localizationGO:0051905220.076
cellular macromolecule biosynthetic processGO:00346452240.074
single organism localizationGO:19025782250.072
melanosome localizationGO:0032400210.071
regulation of macromolecule biosynthetic processGO:00105562250.066
organic substance biosynthetic processGO:19015762890.065
secondary metabolic processGO:001974830.055
nitrogen compound metabolic processGO:00068073190.054
tissue remodelingGO:004877140.050
Mouse
retina development in camera type eyeGO:00600411460.047
camera type eye developmentGO:00430102220.047
Mouse
sensory organ developmentGO:00074233930.046
Mouse
negative regulation of cellular processGO:00485232830.045
Human Mouse
macromolecule biosynthetic processGO:00090592270.043
positive regulation of catabolic processGO:000989640.043
regulation of nucleobase containing compound metabolic processGO:00192192500.042
regulation of cell shapeGO:000836010.041
rna metabolic processGO:00160702190.041
regulation of protein transportGO:005122330.041
nucleobase containing compound biosynthetic processGO:00346542050.040
positive regulation of cellular catabolic processGO:003133130.039
biosynthetic processGO:00090582940.038
single organism transportGO:00447652060.038
generation of neuronsGO:00486993850.037
morphogenesis of an epitheliumGO:00020093330.037
epithelial cell differentiationGO:00308551160.037
growthGO:00400071740.036
cell morphogenesisGO:00009022890.036
larval developmentGO:000216420.035
vesicle localizationGO:0051648270.035
cellular component morphogenesisGO:00329893360.035
regulation of biosynthetic processGO:00098892500.035
regulation of multicellular organism growthGO:004001440.035
cellular localizationGO:0051641970.034
transportGO:00068102200.034
regulation of primary metabolic processGO:00800903110.034
neuron differentiationGO:00301823530.034
regulation of cellular amine metabolic processGO:003323800.033
regulation of establishment of protein localizationGO:007020140.033
cellular component movementGO:00069283350.032
agingGO:000756820.032
cellular biosynthetic processGO:00442492860.032
multicellular organism growthGO:003526440.032
cell part morphogenesisGO:00329902460.032
establishment of localizationGO:00512342440.032
melanin biosynthetic processGO:004243810.031
regulation of nitrogen compound metabolic processGO:00511712510.031
maintenance of locationGO:005123540.031
cellular aromatic compound metabolic processGO:00067252950.031
organic cyclic compound biosynthetic processGO:19013622230.031
cellular amine metabolic processGO:004410620.030
establishment of vesicle localizationGO:0051650240.030
single organism organelle organizationGO:19025891990.029
regulation of purine nucleotide catabolic processGO:003312120.029
embryonic skeletal system morphogenesisGO:0048704930.029
amine metabolic processGO:000930820.029
organelle organizationGO:00069962270.028
embryonic organ morphogenesisGO:00485622740.028
specification of symmetryGO:00097992040.028
regulation of nucleotide catabolic processGO:003081120.027
mesenchyme developmentGO:00604851270.027
embryonic skeletal joint morphogenesisGO:006027230.026
carboxylic acid metabolic processGO:0019752220.026
nucleic acid templated transcriptionGO:00976591810.026
organic cyclic compound metabolic processGO:19013603010.026
cilium morphogenesisGO:0060271850.025
positive regulation of purine nucleotide catabolic processGO:003312310.025
heart developmentGO:00075073130.025
gene expressionGO:00104672520.025
inner ear developmentGO:00488391260.025
oxoacid metabolic processGO:0043436310.025
regulation of blood pressureGO:000821710.025
regulation of muscle contractionGO:000693730.025
sensory organ morphogenesisGO:00905962000.025
cellular macromolecule metabolic processGO:00442603910.025
melanin metabolic processGO:000658220.025
regulation of gtp catabolic processGO:003312420.024
regulation of cellular macromolecule biosynthetic processGO:20001122220.024
protein secretionGO:000930610.024
guanosine containing compound catabolic processGO:190106920.024
skeletal system morphogenesisGO:00487051020.023
regulation of endocrine processGO:004406020.023
regulation of systemic arterial blood pressureGO:000307310.023
ion transmembrane transportGO:0034220910.023
developmental growthGO:00485891660.023
ear developmentGO:00435831270.023
regulation of cellular biosynthetic processGO:00313262450.023
establishment of organelle localizationGO:0051656450.023
establishment of localization in cellGO:0051649770.023
proteasomal protein catabolic processGO:001049820.023
striated muscle cell differentiationGO:00511461290.023
gtp metabolic processGO:004603940.023
urogenital system developmentGO:0001655970.023
guanosine containing compound metabolic processGO:190106840.022
organelle localizationGO:0051640490.022
positive regulation of nucleoside metabolic processGO:004597910.022
lipid storageGO:001991510.022
cellular component assemblyGO:00226071700.022
Human
purine nucleoside monophosphate catabolic processGO:000912840.022
cognitionGO:005089010.021
digestive system developmentGO:00551232890.021
muscle structure developmentGO:00610611960.021
ribonucleoside monophosphate catabolic processGO:000915840.021
protein localizationGO:0008104400.021
cellular component assembly involved in morphogenesisGO:00109271070.021
positive regulation of epithelial cell proliferationGO:005067910.021
nucleobase containing compound metabolic processGO:00061392740.021
extrinsic apoptotic signaling pathwayGO:009719130.021
cilium organizationGO:0044782710.020
cardiac muscle tissue developmentGO:0048738480.020
positive regulation of translationGO:004572710.020
skeletal system developmentGO:00015011810.020
cardiac atrium developmentGO:000323040.020
regulation of cellular amino acid metabolic processGO:000652100.020
regulation of rna metabolic processGO:00512522240.020
actin filament based movementGO:003004810.020
regulation of nucleoside metabolic processGO:000911820.020
cellular amino acid metabolic processGO:000652070.020
hemopoiesisGO:00300971830.020
Mouse
heterocycle metabolic processGO:00464832900.020
stem cell maintenanceGO:001982740.020
organonitrogen compound metabolic processGO:1901564740.020
transcription dna templatedGO:00063511810.020
otic vesicle morphogenesisGO:0071600340.020
regulation of rna biosynthetic processGO:20011412130.020
positive regulation of nitrogen compound metabolic processGO:0051173690.019
Human Mouse
positive regulation of biological processGO:00485182530.019
Human Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.019
circulatory system processGO:0003013870.019
small molecule metabolic processGO:0044281770.019
regulation of actin filament based movementGO:190311510.019
renal tubule morphogenesisGO:006133310.019
brain developmentGO:00074202930.019
cellular protein catabolic processGO:004425740.019
organelle assemblyGO:00709251100.019
regulation of cell activationGO:005086510.019
pigment granule organizationGO:004875340.019
regulation of synapse organizationGO:005080730.018
mitochondrion organizationGO:000700540.018
organic substance transportGO:0071702580.018
cell projection organizationGO:00300302840.018
fin developmentGO:0033333770.018
negative regulation of protein kinase activityGO:000646940.018
adult behaviorGO:003053420.018
eye developmentGO:00016542770.018
Mouse
stem cell proliferationGO:007208940.018
kupffer s vesicle developmentGO:0070121500.018
transmembrane transportGO:00550851200.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
regulation of epithelial cell proliferationGO:005067830.018
cell surface receptor signaling pathwayGO:00071663250.018
Mouse
regulation of protein catabolic processGO:004217610.018
cellular response to external stimulusGO:007149620.018
regulation of cellular ketone metabolic processGO:001056570.017
phagocytosisGO:000690930.017
cell migrationGO:00164772370.017
regulation of metabolic processGO:00192223590.017
determination of bilateral symmetryGO:00098552040.017
camera type eye morphogenesisGO:00485931080.017
positive regulation of transportGO:005105020.017
positive regulation of nucleotide catabolic processGO:003081310.017
nucleoside monophosphate catabolic processGO:000912540.017
regulation of cytokine productionGO:000181730.017
digestive tract developmentGO:00485652650.017
kidney developmentGO:0001822920.017
head developmentGO:00603223030.016
determination of left right symmetryGO:00073681790.016
embryonic hemopoiesisGO:0035162530.016
neural crest cell developmentGO:0014032620.016
alpha amino acid metabolic processGO:190160530.016
endocrine processGO:005088620.016
ribosomal small subunit biogenesisGO:004227420.016
positive regulation of rna metabolic processGO:0051254590.016
Human Mouse
activation of mapk activityGO:000018730.016
cellular amide metabolic processGO:004360340.016
response to drugGO:004249330.016
negative regulation of response to stimulusGO:00485851040.016
gtp catabolic processGO:000618420.016
cell projection morphogenesisGO:00488582440.016
osteoclast differentiationGO:003031610.016
Mouse
nucleic acid metabolic processGO:00903042440.016
developmental programmed cell deathGO:001062340.016
muscle cell differentiationGO:00426921390.016
regulation of synapse assemblyGO:005196330.016
regulation of gtpase activityGO:004308720.015
negative regulation of protein phosphorylationGO:000193340.015
regulation of tube sizeGO:003515020.015
cellular protein modification processGO:00064641000.015
positive regulation of gtpase activityGO:004354710.015
regulation of response to stimulusGO:00485832690.015
regulation of developmental processGO:00507932470.015
Mouse
regulation of rho protein signal transductionGO:003502320.015
action potentialGO:0001508190.015
positive regulation of cellular biosynthetic processGO:0031328680.015
Human Mouse
renal system developmentGO:0072001940.015
compound eye developmentGO:004874920.015
regulation of transcription dna templatedGO:00063552130.015
centrosome organizationGO:005129710.015
regulation of cardiac muscle contractionGO:005511720.015
melanocyte migrationGO:009732440.015
negative regulation of signal transductionGO:0009968940.015
antimicrobial humoral responseGO:001973020.015
positive regulation of cellular amine metabolic processGO:003324000.015
leukocyte proliferationGO:007066110.015
tube morphogenesisGO:00352393490.014
cilium assemblyGO:0042384580.014
regulation of neural precursor cell proliferationGO:200017730.014
regulation of gene expressionGO:00104682650.014
cellular response to biotic stimulusGO:007121630.014
positive regulation of gtp catabolic processGO:003312610.014
single organism metabolic processGO:00447102170.014
embryonic skeletal joint developmentGO:007249830.014
cellular protein metabolic processGO:00442671290.014
digestive tract morphogenesisGO:00485462310.014
nucleocytoplasmic transportGO:000691340.014
regulation of neural retina developmentGO:006107420.014
regulation of retina development in camera type eyeGO:190286620.014
cell morphogenesis involved in differentiationGO:00009041950.014
endosomal transportGO:001619720.014
regulation of jak stat cascadeGO:004642530.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
cardiac muscle contractionGO:006004860.014
negative regulation of signalingGO:0023057960.014
embryonic skeletal system developmentGO:0048706970.014
embryonic organ developmentGO:00485683810.014
meiotic cell cycle processGO:190304630.014
catechol containing compound metabolic processGO:000971220.014
protein localization to nucleusGO:003450430.013
cardiac atrium morphogenesisGO:000320920.013
ubiquitin dependent protein catabolic processGO:000651130.013
phenol containing compound biosynthetic processGO:004618940.013
autophagyGO:000691440.013
transcription from rna polymerase ii promoterGO:0006366800.013
cellular ketone metabolic processGO:0042180110.013
neural crest cell differentiationGO:0014033720.013
cellular response to lipopolysaccharideGO:007122230.013
signal transduction in absence of ligandGO:003803410.013
negative regulation of cytokine productionGO:000181810.013
regulation of cytoplasmic transportGO:190364940.013
positive regulation of jak stat cascadeGO:004642720.013
cardiocyte differentiationGO:0035051440.013
protein complex disassemblyGO:004324110.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
striated muscle tissue developmentGO:00147061100.013
proteolysis involved in cellular protein catabolic processGO:005160330.012
cellular component disassemblyGO:002241110.012
neuroblast proliferationGO:000740520.012
cartilage developmentGO:0051216960.012
regulation of protein localization to nucleusGO:190018020.012
ovulation cycleGO:004269820.012
meiotic nuclear divisionGO:000712640.012
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.012
pigment cell differentiationGO:0050931380.012
negative regulation of biological processGO:00485193040.012
Human Mouse
alcohol biosynthetic processGO:004616520.012
positive regulation of cellular component biogenesisGO:004408930.012
catecholamine biosynthetic processGO:004242320.012
regulation of protein targetingGO:190353320.012
rna biosynthetic processGO:00327741810.012
membrane fusionGO:006102520.012
lateral inhibitionGO:004633110.012
protein targeting to nucleusGO:004474430.012
regulation of synaptic plasticityGO:004816710.012
eye morphogenesisGO:00485921440.012
lamellipodium assemblyGO:003003210.012
cellular response to extracellular stimulusGO:003166820.012
vasculature developmentGO:00019442780.012
exocytosisGO:000688710.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
protein importGO:001703830.012
cell fate commitmentGO:0045165990.012
Mouse
peptide metabolic processGO:000651810.012
germ line stem cell maintenanceGO:003071820.012
cellular nitrogen compound metabolic processGO:00346412900.012
convergent extensionGO:00600261180.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
blood vessel developmentGO:00015682460.012
nuclear importGO:005117030.012
regulation of anatomical structure morphogenesisGO:00226031300.012
actin mediated cell contractionGO:007025210.012
regulation of reproductive processGO:200024140.012
establishment of protein localization to organelleGO:007259440.011
positive regulation of map kinase activityGO:004340630.011
regulation of protein ubiquitinationGO:003139630.011
positive regulation of transcription dna templatedGO:0045893570.011
Human Mouse
regulation of macromolecule metabolic processGO:00602553170.011
response to external stimulusGO:00096052640.011
positive regulation of stress activated mapk cascadeGO:003287430.011
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.011
retina morphogenesis in camera type eyeGO:0060042790.011
cellular response to starvationGO:000926710.011
centrosome cycleGO:000709810.011
response to carbohydrateGO:000974330.011
microtubule organizing center organizationGO:003102310.011
modification dependent macromolecule catabolic processGO:004363230.011
rna modificationGO:000945120.011
regulation of intracellular protein transportGO:003315730.011
regulation of autophagyGO:001050630.011
localization of cellGO:00516742440.011
regulation of signal transductionGO:00099662250.011
intracellular transportGO:0046907320.011
negative regulation of reproductive processGO:200024230.011
atp catabolic processGO:000620040.011
startle responseGO:000196440.011
regulation of striated muscle contractionGO:000694220.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
regulation of cell differentiationGO:00455951420.011
Mouse
central nervous system developmentGO:00074173870.011
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.011
embryonic heart tube developmentGO:00350501330.011
homeostatic processGO:00425921420.011
regulation of multicellular organismal developmentGO:20000262230.011
Mouse
regulation of stem cell proliferationGO:007209120.011
regulation of oxidative stress induced cell deathGO:190320120.011
synaptic growth at neuromuscular junctionGO:005112420.011
cilium movementGO:0003341260.011
regulation of nucleocytoplasmic transportGO:004682220.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
striated muscle cell developmentGO:00550021080.011
modification dependent protein catabolic processGO:001994130.011
regulation of protein complex assemblyGO:004325430.010
neural retina developmentGO:0003407490.010
toll like receptor signaling pathwayGO:000222440.010
regulation of cellular metabolic processGO:00313233200.010
small gtpase mediated signal transductionGO:000726480.010
pigment granule transportGO:0051904190.010
negative regulation of biosynthetic processGO:0009890550.010
Human
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.010
synaptic target recognitionGO:000803910.010
production of molecular mediator of immune responseGO:000244020.010
negative regulation of multi organism processGO:004390130.010
response to stressGO:00069502630.010
liver developmentGO:0001889960.010
regulation of system processGO:0044057400.010
macromolecule modificationGO:00434121110.010
positive regulation of cell cycleGO:004578730.010
caudal fin morphogenesisGO:003514370.010
intracellular signal transductionGO:0035556850.010
carbohydrate homeostasisGO:003350010.010
dopamine metabolic processGO:004241720.010
cardiac muscle cell developmentGO:0055013200.010
enzyme linked receptor protein signaling pathwayGO:00071671060.010
mesenchymal cell differentiationGO:0048762870.010
rna localizationGO:000640340.010
positive regulation of cell adhesionGO:004578510.010

mitfb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
immune system diseaseDOID:291400.023
musculoskeletal system diseaseDOID:1700.017
connective tissue diseaseDOID:6500.017
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.013
cancerDOID:16200.013
nervous system diseaseDOID:86300.012