Danio rerio

0 known processes

tk2

thymidine kinase 2, mitochondrial

(Aliases: zgc:100948)

tk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.200
mitochondrion organizationGO:000700540.137
agingGO:000756820.092
purine nucleoside monophosphate catabolic processGO:000912840.084
nitrogen compound metabolic processGO:00068073190.068
response to topologically incorrect proteinGO:003596620.066
maintenance of locationGO:005123540.066
regulation of cell deathGO:00109411030.061
olfactory bulb developmentGO:002177240.058
proteasomal protein catabolic processGO:001049820.054
cellular modified amino acid metabolic processGO:000657530.052
response to oxygen radicalGO:000030520.051
circulatory system processGO:0003013870.051
entrainment of circadian clockGO:000964920.049
regulation of tube sizeGO:003515020.048
cell substrate adhesionGO:003158940.047
ribonucleoside monophosphate catabolic processGO:000915840.047
biosynthetic processGO:00090582940.047
system processGO:00030081850.047
cellular macromolecule biosynthetic processGO:00346452240.046
positive regulation of cell cycleGO:004578730.046
lipid storageGO:001991510.044
alpha amino acid metabolic processGO:190160530.044
nucleoside monophosphate catabolic processGO:000912540.044
organic cyclic compound metabolic processGO:19013603010.043
locomotionGO:00400113130.043
carboxylic acid metabolic processGO:0019752220.043
regulation of metabolic processGO:00192223590.043
signal transductionGO:00071654550.042
head developmentGO:00603223030.041
blood circulationGO:0008015870.041
single organism metabolic processGO:00447102170.040
regulation of autophagyGO:001050630.040
olfactory lobe developmentGO:002198840.040
gastrulationGO:00073692080.039
purine ribonucleoside monophosphate catabolic processGO:000916940.039
organic acid metabolic processGO:0006082310.038
regulation of nitrogen compound metabolic processGO:00511712510.038
lipid homeostasisGO:005508830.036
establishment of localizationGO:00512342440.036
regulation of synaptic plasticityGO:004816710.036
regulation of nucleic acid templated transcriptionGO:19035062130.035
regulation of rna biosynthetic processGO:20011412130.035
negative regulation of biological processGO:00485193040.035
female sex differentiationGO:004666040.034
cellular response to radiationGO:007147840.034
very long chain fatty acid metabolic processGO:000003840.034
regulation of protein modification by small protein conjugation or removalGO:190332030.034
fatty acid biosynthetic processGO:000663340.034
nucleobase containing compound metabolic processGO:00061392740.034
central nervous system developmentGO:00074173870.033
digestive system developmentGO:00551232890.033
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.033
modification dependent protein catabolic processGO:001994130.033
cellular macromolecule metabolic processGO:00442603910.033
nuclear transportGO:005116940.033
proteolysis involved in cellular protein catabolic processGO:005160330.033
transportGO:00068102200.032
positive regulation of apoptotic signaling pathwayGO:200123510.031
atp catabolic processGO:000620040.031
response to nutrientGO:000758430.031
oxoacid metabolic processGO:0043436310.031
regulation of developmental processGO:00507932470.031
digestive tract morphogenesisGO:00485462310.031
negative regulation of protein import into nucleusGO:004230820.030
regulation of protein ubiquitinationGO:003139630.030
cellular nitrogen compound metabolic processGO:00346412900.030
regulation of macromolecule metabolic processGO:00602553170.030
peptide metabolic processGO:000651810.030
reciprocal meiotic recombinationGO:000713110.029
regulation of cell activationGO:005086510.029
regulation of blood vessel sizeGO:005088020.029
cellular response to external stimulusGO:007149620.028
response to stressGO:00069502630.028
transcription from rna polymerase ii promoterGO:0006366800.028
positive regulation of biological processGO:00485182530.027
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.027
nucleic acid metabolic processGO:00903042440.027
positive regulation of catabolic processGO:000989640.026
modification dependent macromolecule catabolic processGO:004363230.026
chordate embryonic developmentGO:00430092710.026
carbohydrate homeostasisGO:003350010.026
embryo development ending in birth or egg hatchingGO:00097922710.026
organic cyclic compound biosynthetic processGO:19013622230.026
positive regulation of cellular catabolic processGO:003133130.026
guanosine containing compound catabolic processGO:190106920.025
heart developmentGO:00075073130.025
extrinsic apoptotic signaling pathwayGO:009719130.025
locomotory behaviorGO:0007626340.024
regulation of signal transductionGO:00099662250.024
regulation of primary metabolic processGO:00800903110.024
small molecule metabolic processGO:0044281770.024
regulation of rna metabolic processGO:00512522240.024
negative regulation of protein kinase activityGO:000646940.024
macromolecule biosynthetic processGO:00090592270.024
regulation of nucleotide catabolic processGO:003081120.024
transmembrane transportGO:00550851200.024
cell migrationGO:00164772370.024
regulation of inflammatory responseGO:005072720.024
regulation of biological qualityGO:00650082630.023
single organism biosynthetic processGO:0044711710.023
guanosine containing compound metabolic processGO:190106840.023
organonitrogen compound metabolic processGO:1901564740.023
g1 s transition of mitotic cell cycleGO:000008210.023
response to oxidative stressGO:0006979110.023
neurological system processGO:0050877620.023
reactive oxygen species biosynthetic processGO:190340910.023
regulation of multicellular organism growthGO:004001440.023
carboxylic acid biosynthetic processGO:0046394120.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
release of sequestered calcium ion into cytosolGO:005120930.022
negative regulation of protein phosphorylationGO:000193340.022
positive regulation of map kinase activityGO:004340630.022
autophagyGO:000691440.022
cellular amide metabolic processGO:004360340.022
intracellular signal transductionGO:0035556850.022
oxidation reduction processGO:0055114410.022
regulation of blood pressureGO:000821710.022
skin developmentGO:0043588540.022
heterocycle metabolic processGO:00464832900.022
digestive tract developmentGO:00485652650.022
positive regulation of cell adhesionGO:004578510.021
cellular amino acid biosynthetic processGO:000865220.021
positive regulation of translationGO:004572710.021
adult behaviorGO:003053420.021
lateral inhibitionGO:004633110.021
hindbrain developmentGO:0030902910.021
regulation of cellular metabolic processGO:00313233200.021
regulation of cytokine productionGO:000181730.021
rna metabolic processGO:00160702190.021
nucleobase containing compound biosynthetic processGO:00346542050.021
photoreceptor cell developmentGO:0042461400.020
regulation of response to stimulusGO:00485832690.020
cellular biosynthetic processGO:00442492860.020
multicellular organismal response to stressGO:003355520.020
regulation of signalingGO:00230512350.020
response to biotic stimulusGO:0009607970.020
regulation of dna templated transcription in response to stressGO:004362000.020
regionalizationGO:00030022740.020
positive regulation of stress activated mapk cascadeGO:003287430.020
regulation of macromolecule biosynthetic processGO:00105562250.020
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.020
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.020
b cell differentiationGO:003018310.020
cellular aromatic compound metabolic processGO:00067252950.020
mitochondrial transportGO:000683920.020
positive regulation of cytokine productionGO:000181920.019
locomotor rhythmGO:004547530.019
regulation of production of molecular mediator of immune responseGO:000270010.019
endocardium morphogenesisGO:000316040.019
sensory organ developmentGO:00074233930.019
regulation of reproductive processGO:200024140.019
cellular response to extracellular stimulusGO:003166820.019
regulation of bindingGO:005109830.019
lipid metabolic processGO:0006629520.019
negative regulation of epithelial cell proliferationGO:005068010.019
positive regulation of jnk cascadeGO:004633030.019
protein localization to nucleusGO:003450430.019
positive regulation of gene expressionGO:0010628710.019
regulation of protein transportGO:005122330.019
brain developmentGO:00074202930.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
negative regulation of kinase activityGO:003367340.019
negative regulation of cellular processGO:00485232830.019
meiosis iGO:000712710.019
peripheral nervous system developmentGO:0007422550.019
cellular response to nutrient levelsGO:003166920.019
anterior posterior pattern specificationGO:00099521520.019
hormone biosynthetic processGO:004244630.018
negative regulation of macromolecule metabolic processGO:0010605760.018
gtp metabolic processGO:004603940.018
regulation of purine nucleotide catabolic processGO:003312120.018
organic substance biosynthetic processGO:19015762890.018
regulation of multicellular organismal developmentGO:20000262230.018
ion transmembrane transportGO:0034220910.018
cellular amine metabolic processGO:004410620.018
regulation of circadian rhythmGO:004275240.018
response to organic substanceGO:00100331530.018
very long chain fatty acid biosynthetic processGO:004276140.018
single organism transportGO:00447652060.018
immune system processGO:00023762410.018
regulation of response to oxidative stressGO:190288220.018
regulation of establishment of protein localizationGO:007020140.018
cation transportGO:0006812810.018
single organism localizationGO:19025782250.018
regulation of membrane potentialGO:0042391230.018
small molecule biosynthetic processGO:0044283160.018
gtp catabolic processGO:000618420.018
synaptic growth at neuromuscular junctionGO:005112420.017
cellular response to oxygen radicalGO:007145020.017
developmental programmed cell deathGO:001062340.017
cellular response to light stimulusGO:007148240.017
cellular nitrogen compound biosynthetic processGO:00442712180.017
response to monosaccharideGO:003428430.017
antimicrobial humoral responseGO:001973020.017
regulation of organelle assemblyGO:190211540.017
dicarboxylic acid metabolic processGO:004364810.017
cellular response to decreased oxygen levelsGO:003629410.017
inorganic cation transmembrane transportGO:0098662500.017
eye developmentGO:00016542770.017
multicellular organism growthGO:003526440.017
positive regulation of immune effector processGO:000269930.017
programmed cell deathGO:00125011190.017
cellular response to starvationGO:000926710.017
protein dephosphorylationGO:000647030.017
regulation of cell substrate adhesionGO:001081010.017
regulation of biosynthetic processGO:00098892500.017
cellular response to stressGO:0033554620.017
cellular amino acid metabolic processGO:000652070.017
establishment of protein localization to organelleGO:007259440.017
hepaticobiliary system developmentGO:0061008980.017
negative regulation of intracellular protein transportGO:009031730.017
glucose homeostasisGO:004259310.017
regulation of epithelial cell proliferationGO:005067830.016
cognitionGO:005089010.016
determination of intestine left right asymmetryGO:007190820.016
meiotic cell cycle processGO:190304630.016
regulation of dendrite morphogenesisGO:004881430.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
regulation of cell communicationGO:00106462320.016
response to woundingGO:00096111160.016
positive regulation of neuron deathGO:190121610.016
regulation of synapse organizationGO:005080730.016
rna localizationGO:000640340.016
morphogenesis of an epitheliumGO:00020093330.016
negative regulation of sequestering of calcium ionGO:005128340.016
regulation of nucleoside metabolic processGO:000911820.016
regulation of reactive oxygen species metabolic processGO:200037720.016
microtubule organizing center organizationGO:003102310.016
behaviorGO:0007610740.016
response to carbohydrateGO:000974330.016
regulation of response to nutrient levelsGO:003210710.016
homeostatic processGO:00425921420.016
immune system developmentGO:00025201910.016
regulation of cell shapeGO:000836010.016
regulation of dendrite developmentGO:005077330.016
protein stabilizationGO:005082120.016
response to glucoseGO:000974930.016
regulation of cellular response to oxidative stressGO:190040720.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
cell surface receptor signaling pathwayGO:00071663250.015
heterocycle biosynthetic processGO:00181302150.015
response to uvGO:000941130.015
negative regulation of response to stimulusGO:00485851040.015
cellular carbohydrate metabolic processGO:004426240.015
entrainment of circadian clock by photoperiodGO:004315310.015
positive regulation of epithelial cell differentiationGO:003085820.015
negative regulation of protein transportGO:005122430.015
sensory perception of painGO:001923310.015
nucleocytoplasmic transportGO:000691340.015
response to external stimulusGO:00096052640.015
androgen metabolic processGO:000820920.015
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005930.015
regulation of cellular amine metabolic processGO:003323800.014
striated muscle tissue developmentGO:00147061100.014
cellular response to superoxideGO:007145120.014
heart contractionGO:0060047710.014
energy reserve metabolic processGO:000611220.014
cytoskeleton dependent cytokinesisGO:006164030.014
response to xenobiotic stimulusGO:0009410450.014
adherens junction organizationGO:003433240.014
muscle cell differentiationGO:00426921390.014
small molecule catabolic processGO:004428230.014
response to endogenous stimulusGO:0009719830.014
pancreas developmentGO:0031016840.014
response to hexoseGO:000974630.014
intrinsic apoptotic signaling pathwayGO:0097193200.014
macromolecule modificationGO:00434121110.014
reactive oxygen species metabolic processGO:007259360.014
amine metabolic processGO:000930820.014
muscle fiber developmentGO:0048747520.014
inorganic ion transmembrane transportGO:0098660570.014
regulation of circadian sleep wake cycle sleepGO:004518710.014
spermatid developmentGO:000728620.014
lymphocyte proliferationGO:004665110.014
regulation of jak stat cascadeGO:004642530.013
rna biosynthetic processGO:00327741810.013
mitotic cytokinesisGO:000028130.013
response to alkaloidGO:004327920.013
regulation of nucleocytoplasmic transportGO:004682220.013
adherens junction assemblyGO:003433310.013
estrogen metabolic processGO:000821020.013
regulation of cell cycleGO:0051726520.013
protein metabolic processGO:00195381830.013
monocarboxylic acid biosynthetic processGO:0072330120.013
cellular respirationGO:004533330.013
secondary metabolic processGO:001974830.013
membrane lipid biosynthetic processGO:004646720.013
regulation of multicellular organismal processGO:00512392770.013
single organism nuclear importGO:190259330.013
protein homooligomerizationGO:005126030.013
regulation of protein import into nucleusGO:004230620.013
reciprocal dna recombinationGO:003582510.013
positive regulation of transportGO:005105020.013
mononuclear cell proliferationGO:003294310.013
cytokinetic processGO:003250620.013
negative regulation of protein localization to nucleusGO:190018120.013
response to glucocorticoidGO:005138410.013
regulation of response to extracellular stimulusGO:003210410.013
central nervous system neuron developmentGO:0021954290.013
cytoplasm organizationGO:000702840.013
startle responseGO:000196440.013
response to methylmercuryGO:0051597110.013
positive regulation of cellular amine metabolic processGO:003324000.013
regulation of gtpase activityGO:004308720.013
b cell activationGO:004211320.013
regulation of organ growthGO:004662030.013
exocytosisGO:000688710.013
regulation of intracellular protein transportGO:003315730.013
muscle cell migrationGO:001481240.013
cellular protein catabolic processGO:004425740.013
cytokinesisGO:000091030.012
long chain fatty acid metabolic processGO:000167610.012
removal of superoxide radicalsGO:001943020.012
nucleic acid templated transcriptionGO:00976591810.012
gland developmentGO:00487321430.012
regulation of apoptotic processGO:0042981980.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
auditory receptor cell fate commitmentGO:000991240.012
er nucleus signaling pathwayGO:000698420.012
sensory organ morphogenesisGO:00905962000.012
positive regulation of muscle organ developmentGO:004863610.012
regulation of cytoplasmic transportGO:190364940.012
neuron fate determinationGO:004866420.012
regulation of systemic arterial blood pressureGO:000307310.012
oocyte maturationGO:000155640.012
activation of mapk activityGO:000018730.012
mitotic dna damage checkpointGO:004477340.012
deathGO:00162651210.012
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.012
myeloid cell developmentGO:0061515320.012
positive regulation of nucleoside metabolic processGO:004597910.012
multi organism processGO:00517041340.012
ovarian follicle developmentGO:000154120.012
tube morphogenesisGO:00352393490.012
response to superoxideGO:000030320.012
regulation of oxidative stress induced cell deathGO:190320120.012
response to drugGO:004249330.012
response to transition metal nanoparticleGO:1990267280.012
organic acid biosynthetic processGO:0016053120.012
regulation of cell developmentGO:00602841000.012
posterior lateral line system developmentGO:0048915460.012
cellular response to hypoxiaGO:007145610.012
neuron differentiationGO:00301823530.012
gene expressionGO:00104672520.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
photoreceptor cell differentiationGO:0046530550.012
smooth muscle contractionGO:000693920.012
stem cell maintenanceGO:001982740.012
cellular response to oxygen levelsGO:007145310.012
regulation of gene expressionGO:00104682650.012
cell deathGO:00082191210.011
compound eye developmentGO:004874920.011
response to unfolded proteinGO:000698620.011
cellular component biogenesisGO:00440851780.011
ubiquitin dependent protein catabolic processGO:000651130.011
spermatid differentiationGO:004851520.011
androgen biosynthetic processGO:000670210.011
protein targeting to nucleusGO:004474430.011
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.011
sequestering of metal ionGO:005123830.011
cellular response to reactive oxygen speciesGO:003461420.011
leukocyte proliferationGO:007066110.011
positive regulation of neuron apoptotic processGO:004352510.011
positive regulation of cell substrate adhesionGO:001081110.011
response to inorganic substanceGO:0010035380.011
carbohydrate biosynthetic processGO:001605110.011
cellular response to molecule of bacterial originGO:007121930.011
chemical homeostasisGO:0048878490.011
exocrine pancreas developmentGO:0031017280.011
retina layer formationGO:0010842240.011
response to virusGO:0009615210.011
cellular response to drugGO:003569010.011
vacuolar transportGO:000703420.011
cation transmembrane transportGO:0098655650.011
ovulation cycle processGO:002260220.011
production of molecular mediator of immune responseGO:000244020.011
positive regulation of secretionGO:005104710.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
cell cycle arrestGO:000705010.011
neurotransmitter transportGO:000683620.011
protein localization to plasma membraneGO:007265910.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
extracellular matrix organizationGO:0030198270.011
regulation of gtp catabolic processGO:003312420.011
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.011
protein importGO:001703830.011
regulation of cellular ketone metabolic processGO:001056570.011
mitotic dna integrity checkpointGO:004477440.011
endosomal transportGO:001619720.011
calcium ion transport into cytosolGO:006040230.011
regulation of calcium ion transportGO:005192420.011
water homeostasisGO:003010440.011
cell projection morphogenesisGO:00488582440.011
regulation of mrna processingGO:005068430.011
neuron neuron synaptic transmissionGO:000727010.011
regulation of mitochondrion organizationGO:001082110.010
negative regulation of catabolic processGO:000989530.010
regulation of skeletal muscle tissue developmentGO:004864140.010
regulation of transcription dna templatedGO:00063552130.010
ion homeostasisGO:0050801410.010
embryonic organ developmentGO:00485683810.010
regulation of photoreceptor cell differentiationGO:004653220.010
g protein coupled receptor signaling pathwayGO:0007186740.010
nuclear importGO:005117030.010
regulation of protein bindingGO:004339330.010
epidermis developmentGO:0008544480.010
negative regulation of autophagyGO:001050710.010

tk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.040
disease of metabolismDOID:001466700.040
nervous system diseaseDOID:86300.022
disease of anatomical entityDOID:700.022
disease of cellular proliferationDOID:1456600.018
musculoskeletal system diseaseDOID:1700.013
cancerDOID:16200.013
cardiovascular system diseaseDOID:128700.011
muscular diseaseDOID:008000000.011
organ system cancerDOID:005068600.010