Danio rerio

0 known processes

cast

calpastatin

(Aliases: MGC194249,sb:cb966,zgc:194249)

cast biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of photoreceptor cell differentiationGO:004653220.352
adherens junction organizationGO:003433240.336
adherens junction maintenanceGO:003433420.309
protein metabolic processGO:00195381830.291
skin developmentGO:0043588540.258
heart developmentGO:00075073130.255
dorsal convergenceGO:0060030140.229
larval developmentGO:000216420.216
response to organic substanceGO:00100331530.209
pectoral fin developmentGO:0033339500.177
regulation of epithelial cell proliferationGO:005067830.176
cell junction maintenanceGO:003433120.171
response to stressGO:00069502630.169
embryonic heart tube developmentGO:00350501330.168
cognitionGO:005089010.157
vesicle localizationGO:0051648270.153
agingGO:000756820.139
brain developmentGO:00074202930.131
cell matrix adhesionGO:000716040.130
epithelial cell differentiationGO:00308551160.129
regulation of synapse assemblyGO:005196330.122
sensory organ developmentGO:00074233930.120
photoreceptor cell differentiationGO:0046530550.116
cellular component maintenanceGO:004395430.114
nuclear transportGO:005116940.112
cell morphogenesis involved in differentiationGO:00009041950.110
cell substrate adhesionGO:003158940.109
cell adhesionGO:0007155400.107
somite developmentGO:0061053960.103
tube morphogenesisGO:00352393490.103
regulation of wound healingGO:006104120.103
cell projection organizationGO:00300302840.101
regulation of inflammatory responseGO:005072720.099
central nervous system developmentGO:00074173870.098
nucleic acid templated transcriptionGO:00976591810.096
regulation of synapse organizationGO:005080730.096
epidermis developmentGO:0008544480.096
cell morphogenesis involved in neuron differentiationGO:00486671630.095
embryonic organ developmentGO:00485683810.091
regulation of neurogenesisGO:0050767870.091
cell fate commitmentGO:0045165990.091
cellular response to chemical stimulusGO:00708871570.088
regulation of multicellular organismal processGO:00512392770.087
cellular component morphogenesisGO:00329893360.087
cellular response to starvationGO:000926710.086
regulation of establishment of protein localizationGO:007020140.085
regulation of synaptic plasticityGO:004816710.085
neuron projection developmentGO:00311751800.084
heart morphogenesisGO:00030071560.083
regulation of intracellular protein transportGO:003315730.083
nucleocytoplasmic transportGO:000691340.081
protein importGO:001703830.080
amine metabolic processGO:000930820.080
regulation of multicellular organismal developmentGO:20000262230.078
regulation of erk1 and erk2 cascadeGO:007037240.078
response to external biotic stimulusGO:0043207970.075
regulation of synaptic growth at neuromuscular junctionGO:000858210.074
camera type eye developmentGO:00430102220.074
cranial nerve developmentGO:0021545420.073
synaptic vesicle localizationGO:009747910.071
hair cell differentiationGO:0035315320.071
cellular macromolecule metabolic processGO:00442603910.070
camera type eye morphogenesisGO:00485931080.069
regulation of cell matrix adhesionGO:000195210.069
protein localization to nucleusGO:003450430.066
biological adhesionGO:0022610400.066
regulation of anatomical structure morphogenesisGO:00226031300.066
positive regulation of biological processGO:00485182530.065
regulation of protein transportGO:005122330.064
cell migrationGO:00164772370.062
multicellular organism growthGO:003526440.061
cellular nitrogen compound biosynthetic processGO:00442712180.059
regulation of biological qualityGO:00650082630.058
system processGO:00030081850.058
cellular component movementGO:00069283350.058
cellular response to external stimulusGO:007149620.057
neuron differentiationGO:00301823530.057
regulation of cellular amine metabolic processGO:003323800.055
response to biotic stimulusGO:0009607970.055
muscle tissue developmentGO:00605371100.055
negative regulation of response to stimulusGO:00485851040.055
transportGO:00068102200.054
defense responseGO:0006952470.054
odontogenesis of dentin containing toothGO:004247510.053
small molecule metabolic processGO:0044281770.052
cellular response to nutrient levelsGO:003166920.052
positive regulation of cellular processGO:00485222010.051
meiotic cell cycle processGO:190304630.051
head developmentGO:00603223030.051
synaptic growth at neuromuscular junctionGO:005112420.051
aromatic compound biosynthetic processGO:00194382170.051
nerve developmentGO:0021675450.050
regulation of response to stimulusGO:00485832690.050
protein localizationGO:0008104400.050
regulation of axonogenesisGO:0050770320.050
negative regulation of autophagyGO:001050710.050
erythrocyte homeostasisGO:0034101550.049
response to external stimulusGO:00096052640.048
response to other organismGO:0051707970.048
cytokine mediated signaling pathwayGO:001922170.048
regulation of multicellular organism growthGO:004001440.048
cardiac conductionGO:006133730.048
specification of symmetryGO:00097992040.047
negative regulation of epithelial cell proliferationGO:005068010.047
single organism nuclear importGO:190259330.046
positive regulation of wound healingGO:009030310.046
protein targeting to nucleusGO:004474430.046
positive regulation of cellular component biogenesisGO:004408930.046
sensory organ morphogenesisGO:00905962000.045
synaptic transmissionGO:0007268350.045
positive regulation of cellular amine metabolic processGO:003324000.045
cellular ketone metabolic processGO:0042180110.045
positive regulation of cellular amino acid metabolic processGO:004576400.044
oocyte maturationGO:000155640.044
single organism localizationGO:19025782250.044
single organismal cell cell adhesionGO:0016337290.043
regulation of cell shapeGO:000836010.042
synapse assemblyGO:000741690.042
regulation of cell differentiationGO:00455951420.042
eye developmentGO:00016542770.042
positive regulation of cell cycleGO:004578730.042
ameboidal type cell migrationGO:00016671430.042
multicellular organismal signalingGO:0035637220.042
protein import into nucleusGO:000660630.042
determination of left right symmetryGO:00073681790.041
oocyte anterior posterior axis specificationGO:000731440.040
neurotransmitter secretionGO:000726920.040
retina morphogenesis in camera type eyeGO:0060042790.040
immune system processGO:00023762410.040
cellular aromatic compound metabolic processGO:00067252950.040
cellular response to growth factor stimulusGO:0071363390.039
organic acid metabolic processGO:0006082310.039
response to endogenous stimulusGO:0009719830.039
regulation of developmental processGO:00507932470.039
negative regulation of protein transportGO:005122430.039
localization of cellGO:00516742440.039
establishment of protein localization to organelleGO:007259440.039
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.039
muscle structure developmentGO:00610611960.039
cellular response to extracellular stimulusGO:003166820.038
regulation of macromolecule metabolic processGO:00602553170.038
retina development in camera type eyeGO:00600411460.038
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.037
regulation of signal transductionGO:00099662250.037
regulation of neurological system processGO:003164420.037
cell morphogenesisGO:00009022890.037
eye morphogenesisGO:00485921440.036
cell cycle g1 s phase transitionGO:004484310.036
macromolecule biosynthetic processGO:00090592270.036
regulation of axon extensionGO:0030516240.036
phosphate containing compound metabolic processGO:00067961080.035
embryo development ending in birth or egg hatchingGO:00097922710.035
regulation of heart contractionGO:0008016320.035
regulation of neurotransmitter transportGO:005158810.035
organelle localizationGO:0051640490.035
nuclear importGO:005117030.035
axon developmentGO:00615641660.035
actin filament based movementGO:003004810.035
axonogenesisGO:00074091520.035
cell fate specificationGO:0001708680.034
neuromuscular synaptic transmissionGO:000727420.034
response to nutrientGO:000758430.034
synaptic vesicle transportGO:004848910.034
organonitrogen compound metabolic processGO:1901564740.034
cellular component assembly involved in morphogenesisGO:00109271070.034
g1 s transition of mitotic cell cycleGO:000008210.034
cellular amine metabolic processGO:004410620.033
response to chemicalGO:00422213200.033
axonal fasciculationGO:0007413110.033
cell surface receptor signaling pathwayGO:00071663250.033
positive regulation of epithelial cell migrationGO:001063420.033
oxoacid metabolic processGO:0043436310.033
regulation of cellular ketone metabolic processGO:001056570.033
water homeostasisGO:003010440.032
cellular nitrogen compound metabolic processGO:00346412900.032
somitogenesisGO:0001756870.032
regulation of cell developmentGO:00602841000.032
keratinocyte differentiationGO:003021600.031
regulation of primary metabolic processGO:00800903110.031
germ line stem cell divisionGO:004207810.031
dorsal motor nucleus of vagus nerve developmentGO:002174440.031
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.031
synaptic vesicle endocytosisGO:004848810.031
response to growth factorGO:0070848390.030
single organism biosynthetic processGO:0044711710.030
embryonic hemopoiesisGO:0035162530.030
organic cyclic compound biosynthetic processGO:19013622230.029
regulation of nucleocytoplasmic transportGO:004682220.029
cell aggregationGO:009874330.029
regulation of bindingGO:005109830.029
protein modification processGO:00362111000.029
neural tube developmentGO:0021915620.029
cardiac muscle tissue morphogenesisGO:005500870.029
cellular protein metabolic processGO:00442671290.029
cartilage condensationGO:000150230.029
cell part morphogenesisGO:00329902460.029
single organism metabolic processGO:00447102170.028
regulation of purine nucleotide catabolic processGO:003312120.028
neurotransmitter transportGO:000683620.028
meiotic nuclear divisionGO:000712640.028
muscle cell differentiationGO:00426921390.028
small gtpase mediated signal transductionGO:000726480.028
regulation of nervous system developmentGO:0051960900.027
generation of neuronsGO:00486993850.027
negative regulation of defense responseGO:003134820.027
reciprocal meiotic recombinationGO:000713110.027
gland developmentGO:00487321430.027
glucose homeostasisGO:004259310.027
cellular localizationGO:0051641970.026
establishment of vesicle localizationGO:0051650240.026
cellular response to organic substanceGO:00713101050.026
positive regulation of cell adhesionGO:004578510.026
cellular component biogenesisGO:00440851780.026
long chain fatty acid metabolic processGO:000167610.026
urogenital system developmentGO:0001655970.026
regulation of metabolic processGO:00192223590.025
cell cell adhesion involved in gastrulationGO:007058640.025
cell projection morphogenesisGO:00488582440.025
epithelial tube morphogenesisGO:00605621480.025
convergent extensionGO:00600261180.025
cellular amino acid metabolic processGO:000652070.025
regulation of developmental growthGO:0048638380.025
cell motilityGO:00488702440.025
regulation of neuron differentiationGO:0045664560.024
regulation of organ growthGO:004662030.024
positive regulation of cell differentiationGO:0045597300.024
fin developmentGO:0033333770.024
regulation of extent of cell growthGO:0061387290.024
regulation of blood circulationGO:1903522320.024
signal transductionGO:00071654550.024
actin mediated cell contractionGO:007025210.024
regulation of cellular metabolic processGO:00313233200.024
regulation of rna biosynthetic processGO:20011412130.024
reproductive processGO:0022414400.024
stem cell proliferationGO:007208940.024
cellular protein modification processGO:00064641000.024
protein localization to plasma membraneGO:007265910.023
regulation of cellular amino acid metabolic processGO:000652100.023
gene expressionGO:00104672520.023
multicellular organismal reproductive processGO:0048609350.023
protein stabilizationGO:005082120.023
anterior posterior pattern specificationGO:00099521520.023
regulation of response to cytokine stimulusGO:006075930.023
protein phosphorylationGO:0006468470.023
homeostatic processGO:00425921420.023
stem cell maintenanceGO:001982740.023
multi organism processGO:00517041340.023
negative regulation of cytoplasmic transportGO:190365020.023
lipid storageGO:001991510.023
cellular response to endogenous stimulusGO:0071495680.023
positive regulation of catabolic processGO:000989640.022
deathGO:00162651210.022
regulation of transcription dna templatedGO:00063552130.022
endomembrane system organizationGO:0010256130.022
locomotionGO:00400113130.022
desmosome assemblyGO:000215920.022
regionalizationGO:00030022740.022
lens fiber cell developmentGO:007030730.022
neural crest cell developmentGO:0014032620.022
lipid catabolic processGO:001604240.022
chordate embryonic developmentGO:00430092710.022
inner ear developmentGO:00488391260.022
regulation of endothelial cell proliferationGO:000193610.022
response to woundingGO:00096111160.021
cell cell junction organizationGO:0045216100.021
regulation of striated muscle contractionGO:000694220.021
striated muscle tissue developmentGO:00147061100.021
chemotaxisGO:00069351040.021
digestive system developmentGO:00551232890.021
synaptic vesicle recyclingGO:003646510.021
very long chain fatty acid biosynthetic processGO:004276140.021
establishment of localization in cellGO:0051649770.021
negative regulation of nucleocytoplasmic transportGO:004682320.021
establishment or maintenance of bipolar cell polarityGO:0061245120.021
regulation of chromosome segregationGO:005198310.021
positive regulation of signalingGO:0023056560.021
morphogenesis of an epitheliumGO:00020093330.020
ribonucleoside monophosphate catabolic processGO:000915840.020
positive regulation of nucleoside metabolic processGO:004597910.020
regulation of cytoplasmic transportGO:190364940.020
wnt signaling pathwayGO:0016055800.020
polarized epithelial cell differentiationGO:003085940.020
innervationGO:006038430.020
cell proliferationGO:0008283800.020
negative regulation of developmental processGO:0051093650.020
striated muscle cell differentiationGO:00511461290.020
carboxylic acid metabolic processGO:0019752220.020
pronephros developmentGO:0048793690.020
secondary metabolic processGO:001974830.019
nucleobase containing compound biosynthetic processGO:00346542050.019
nucleic acid metabolic processGO:00903042440.019
negative regulation of mapk cascadeGO:004340940.019
segmentationGO:0035282970.019
macromolecule modificationGO:00434121110.019
rna localizationGO:000640340.019
circulatory system processGO:0003013870.019
ear developmentGO:00435831270.019
regulation of response to external stimulusGO:0032101310.019
carbohydrate homeostasisGO:003350010.019
single organism cell adhesionGO:0098602290.019
response to oxygen containing compoundGO:1901700550.019
regulation of dendrite developmentGO:005077330.019
myeloid cell homeostasisGO:0002262560.019
positive regulation of cellular catabolic processGO:003133130.018
pigment cell differentiationGO:0050931380.018
negative regulation of kinase activityGO:003367340.018
developmental pigmentationGO:0048066480.018
negative regulation of small gtpase mediated signal transductionGO:005105810.018
neuron developmentGO:00486662620.018
positive regulation of cell divisionGO:005178120.018
positive regulation of epithelial cell proliferationGO:005067910.018
cell migration involved in gastrulationGO:0042074790.018
single organism cellular localizationGO:1902580460.018
cartilage developmentGO:0051216960.018
rna metabolic processGO:00160702190.018
adult behaviorGO:003053420.018
regulation of glial cell differentiationGO:004568540.018
regulation of signalingGO:00230512350.018
regulation of actin filament based movementGO:190311510.018
organelle assemblyGO:00709251100.018
positive regulation of translationGO:004572710.017
cellular component assemblyGO:00226071700.017
regulation of catalytic activityGO:0050790550.017
negative regulation of signalingGO:0023057960.017
biosynthetic processGO:00090582940.017
inner ear receptor stereocilium organizationGO:006012280.017
action potentialGO:0001508190.017
response to inorganic substanceGO:0010035380.016
membrane invaginationGO:001032410.016
erk1 and erk2 cascadeGO:007037140.016
intracellular transportGO:0046907320.016
reflexGO:006000420.016
mesoderm developmentGO:0007498880.016
cellular protein localizationGO:0034613200.016
regulation of blood pressureGO:000821710.016
heart processGO:0003015710.016
synapse organizationGO:0050808210.016
ectodermal cell fate specificationGO:000171520.016
regulation of cellular component movementGO:0051270550.016
neuron projection morphogenesisGO:00488121610.016
cell junction organizationGO:0034330110.016
histone phosphorylationGO:001657220.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
eye photoreceptor cell developmentGO:0042462300.016
positive regulation of chromosome organizationGO:200125210.016
protein complex subunit organizationGO:0071822460.015
regulation of dna templated transcription in response to stressGO:004362000.015
guanosine containing compound metabolic processGO:190106840.015
carbohydrate derivative biosynthetic processGO:1901137430.015
medulla oblongata developmentGO:002155040.015
regulation of nucleotide catabolic processGO:003081120.015
regulation of embryonic developmentGO:0045995470.015
response to topologically incorrect proteinGO:003596620.015
regulation of immune system processGO:0002682340.015
regulation of heart growthGO:006042020.015
developmental growthGO:00485891660.015
fatty acid elongationGO:003049710.015
humoral immune responseGO:000695950.015
positive regulation of transportGO:005105020.015
negative regulation of synapse assemblyGO:005196420.015
actin cytoskeleton organizationGO:0030036630.015
response to drugGO:004249330.015
digestive tract morphogenesisGO:00485462310.015
neuroblast differentiationGO:001401610.015
cardiac muscle tissue developmentGO:0048738480.015
negative regulation of signal transductionGO:0009968940.015
fertilizationGO:000956630.015
positive regulation of response to stimulusGO:0048584800.015
regulation of eye photoreceptor cell developmentGO:004247820.014
nitrogen compound metabolic processGO:00068073190.014
positive regulation of protein complex assemblyGO:003133420.014
regulation of water loss via skinGO:003356110.014
hindbrain developmentGO:0030902910.014
convergent extension involved in gastrulationGO:0060027710.014
negative regulation of protein localization to nucleusGO:190018120.014
digestive tract developmentGO:00485652650.014
regulation of localizationGO:00328791040.014
intracellular mrna localizationGO:000829810.014
epithelial cell proliferationGO:0050673170.014
positive regulation of ras protein signal transductionGO:004657910.014
transcription dna templatedGO:00063511810.014
glycolipid biosynthetic processGO:000924710.014
carbohydrate derivative metabolic processGO:1901135610.014
negative regulation of cell differentiationGO:0045596460.014
negative regulation of protein import into nucleusGO:004230820.014
negative regulation of multicellular organismal processGO:0051241690.014
intestinal absorptionGO:005089220.014
negative regulation of intracellular protein transportGO:009031730.014
negative regulation of macromolecule metabolic processGO:0010605760.014
cellular response to fatty acidGO:007139830.014
chemosensory behaviorGO:000763510.014
response to monosaccharideGO:003428430.014
cell cell adhesion involved in mesendodermal cell migrationGO:000337010.014
regulation of organ morphogenesisGO:2000027350.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
positive regulation of chromatin modificationGO:190331010.013
regulation of response to woundingGO:1903034110.013
meiosis iGO:000712710.013
embryonic heart tube morphogenesisGO:00031431080.013
gtp metabolic processGO:004603940.013
growthGO:00400071740.013
ras protein signal transductionGO:000726570.013
single organism membrane organizationGO:0044802200.013
regulation of neurotransmitter secretionGO:004692810.013
regulation of protein bindingGO:004339330.013
connective tissue developmentGO:0061448990.013
nucleoside phosphate metabolic processGO:0006753280.013
negative regulation of dna metabolic processGO:005105340.013
regulation of cell substrate adhesionGO:001081010.013
actin filament based processGO:0030029640.013
chemical homeostasisGO:0048878490.013
mesenchyme developmentGO:00604851270.013
osteoclast developmentGO:003603510.013
neuroblast proliferationGO:000740520.013
extrinsic apoptotic signaling pathwayGO:009719130.013
phagocytosis engulfmentGO:000691110.013
ventricular cardiac muscle tissue developmentGO:000322930.013
cardioblast differentiationGO:001000290.013
heterocycle biosynthetic processGO:00181302150.013
regulation of system processGO:0044057400.013
mechanoreceptor differentiationGO:0042490370.013
establishment or maintenance of apical basal cell polarityGO:0035088120.012
response to unfolded proteinGO:000698620.012
atrioventricular canal developmentGO:003630250.012
lateral line system developmentGO:0048925760.012
homeostasis of number of cellsGO:0048872620.012
response to glucoseGO:000974930.012
membrane lipid biosynthetic processGO:004646720.012
pigment cell developmentGO:007028530.012
heart joggingGO:0003146400.012
organic substance biosynthetic processGO:19015762890.012
maintenance of locationGO:005123540.012
dna biosynthetic processGO:007189730.012
ventricular cardiac muscle tissue morphogenesisGO:005501020.012
regulation of molecular functionGO:0065009700.012
cellular carbohydrate metabolic processGO:004426240.012
positive regulation of molecular functionGO:0044093330.012
posttranscriptional regulation of gene expressionGO:0010608140.012
positive regulation of cell activationGO:005086710.012
regulation of cell activationGO:005086510.012
embryonic retina morphogenesis in camera type eyeGO:0060059220.012
organic cyclic compound metabolic processGO:19013603010.012
regulation of cell communicationGO:00106462320.012
positive regulation of neurogenesisGO:0050769240.012
actin polymerization or depolymerizationGO:000815420.012
regulation of cell morphogenesisGO:0022604420.012
phosphorylationGO:0016310690.012
regulation of phosphorus metabolic processGO:0051174430.012
response to lipidGO:0033993600.012
reproductionGO:0000003400.012
epidermal cell differentiationGO:0009913360.012
sexual reproductionGO:0019953360.012
multicellular organism reproductionGO:0032504350.012
axonal defasciculationGO:000741420.012
cellular macromolecule biosynthetic processGO:00346452240.012
cell deathGO:00082191210.012
protein secretionGO:000930610.011
innate immune responseGO:0045087130.011
regulation of autophagyGO:001050630.011
response to organic cyclic compoundGO:0014070510.011
myeloid cell differentiationGO:0030099860.011
epidermis morphogenesisGO:004873040.011
regulation of meiotic cell cycleGO:005144510.011
sphingolipid biosynthetic processGO:003014820.011
hatchingGO:003518840.011
endoderm developmentGO:0007492490.011
negative regulation of protein kinase activityGO:000646940.011
positive regulation of metabolic processGO:00098931080.011
regulation of macromolecule biosynthetic processGO:00105562250.011
guanosine containing compound catabolic processGO:190106920.011
meiotic chromosome segregationGO:004513230.011
behaviorGO:0007610740.011
cellular response to biotic stimulusGO:007121630.011
wound healingGO:0042060900.011
autophagyGO:000691440.011
cell maturationGO:0048469230.011
striated muscle cell developmentGO:00550021080.011

cast disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular diseaseDOID:008000000.148
heart diseaseDOID:11400.148
myopathyDOID:42300.148
cardiovascular system diseaseDOID:128700.148
musculoskeletal system diseaseDOID:1700.148
cardiomyopathyDOID:005070000.148
disease of anatomical entityDOID:700.148
muscle tissue diseaseDOID:6600.148
intrinsic cardiomyopathyDOID:006003600.085
disease of cellular proliferationDOID:1456600.024
organ system cancerDOID:005068600.024
cancerDOID:16200.024
connective tissue diseaseDOID:6500.014
nervous system diseaseDOID:86300.014
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
lysosomal storage diseaseDOID:321100.012
gastrointestinal system cancerDOID:311900.012