Danio rerio

0 known processes

twistnb

TWIST neighbor

twistnb biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.497
embryo development ending in birth or egg hatchingGO:00097922710.120
meiotic nuclear divisionGO:000712640.107
agingGO:000756820.097
nitrogen compound metabolic processGO:00068073190.090
cellular macromolecule metabolic processGO:00442603910.087
cellular aromatic compound metabolic processGO:00067252950.083
regulation of meiotic cell cycleGO:005144510.080
cellular nitrogen compound metabolic processGO:00346412900.076
nuclear transportGO:005116940.076
organic cyclic compound metabolic processGO:19013603010.076
gene expressionGO:00104672520.073
rna metabolic processGO:00160702190.070
heterocycle metabolic processGO:00464832900.064
establishment of localizationGO:00512342440.062
locomotionGO:00400113130.062
maturation of ssu rrnaGO:003049010.058
nucleobase containing compound metabolic processGO:00061392740.058
nucleic acid metabolic processGO:00903042440.057
cellular response to external stimulusGO:007149620.054
protein acetylationGO:000647320.053
nucleocytoplasmic transportGO:000691340.052
transportGO:00068102200.052
regulation of multicellular organism growthGO:004001440.051
positive regulation of cell cycleGO:004578730.051
multicellular organism growthGO:003526440.050
positive regulation of cellular catabolic processGO:003133130.047
positive regulation of transportGO:005105020.046
spindle assemblyGO:005122520.046
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.045
protein localization to nucleusGO:003450430.045
regulation of protein transportGO:005122330.045
meiotic cell cycle processGO:190304630.043
cellular amine metabolic processGO:004410620.042
maintenance of locationGO:005123540.041
immune system developmentGO:00025201910.041
establishment of protein localization to organelleGO:007259440.041
cell migrationGO:00164772370.040
cellular component movementGO:00069283350.039
organelle organizationGO:00069962270.039
single organism transportGO:00447652060.038
amine metabolic processGO:000930820.038
lipid storageGO:001991510.038
positive regulation of catabolic processGO:000989640.038
negative regulation of cellular processGO:00485232830.038
single organism organelle organizationGO:19025891990.037
localization of cellGO:00516742440.036
modification dependent macromolecule catabolic processGO:004363230.036
cellular response to nutrient levelsGO:003166920.036
phagocytosisGO:000690930.036
cellular component biogenesisGO:00440851780.036
regulation of cellular amine metabolic processGO:003323800.035
regulation of cellular metabolic processGO:00313233200.034
internal protein amino acid acetylationGO:000647520.034
guanosine containing compound metabolic processGO:190106840.034
regulation of establishment of protein localizationGO:007020140.034
protein acylationGO:004354330.034
heart developmentGO:00075073130.033
nuclear exportGO:005116810.033
cell motilityGO:00488702440.033
regulation of mrna processingGO:005068430.033
biosynthetic processGO:00090582940.032
regulation of apoptotic processGO:0042981980.032
regulation of cellular amino acid metabolic processGO:000652100.032
cell deathGO:00082191210.032
cytokinesisGO:000091030.032
protein importGO:001703830.032
chordate embryonic developmentGO:00430092710.031
cellular response to starvationGO:000926710.031
guanosine containing compound catabolic processGO:190106920.031
organic substance biosynthetic processGO:19015762890.031
protein import into nucleusGO:000660630.030
gtp metabolic processGO:004603940.030
meiotic chromosome segregationGO:004513230.030
single organism localizationGO:19025782250.030
signal transductionGO:00071654550.030
positive regulation of nitrogen compound metabolic processGO:0051173690.030
single fertilizationGO:000733830.029
immune system processGO:00023762410.029
single organism nuclear importGO:190259330.029
protein targeting to nucleusGO:004474430.029
regulation of intracellular protein transportGO:003315730.029
regulation of macromolecule metabolic processGO:00602553170.029
rna biosynthetic processGO:00327741810.029
response to chemicalGO:00422213200.029
cellular protein catabolic processGO:004425740.029
regulation of protein import into nucleusGO:004230620.028
macromolecule biosynthetic processGO:00090592270.028
organelle assemblyGO:00709251100.028
gtp catabolic processGO:000618420.028
regulation of primary metabolic processGO:00800903110.028
regulation of cytokine productionGO:000181730.028
regulation of cell deathGO:00109411030.028
regulation of bindingGO:005109830.027
regulation of protein targetingGO:190353320.027
regulation of cell shapeGO:000836010.027
cellular ketone metabolic processGO:0042180110.027
regulation of nitrogen compound metabolic processGO:00511712510.027
regulation of cytoplasmic transportGO:190364940.027
regulation of gene expressionGO:00104682650.027
cellular response to extracellular stimulusGO:003166820.026
nucleic acid templated transcriptionGO:00976591810.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
rna localizationGO:000640340.026
regulation of programmed cell deathGO:00430671010.026
positive regulation of cellular component biogenesisGO:004408930.025
ribonucleoside monophosphate catabolic processGO:000915840.025
cellular component disassemblyGO:002241110.025
cellular localizationGO:0051641970.025
developmental growthGO:00485891660.025
positive regulation of cellular amino acid metabolic processGO:004576400.025
response to external stimulusGO:00096052640.025
autophagyGO:000691440.025
cellular component assemblyGO:00226071700.025
reproductionGO:0000003400.025
tube morphogenesisGO:00352393490.024
regulation of protein localization to nucleusGO:190018020.024
apoptotic processGO:00069151160.024
centrosome organizationGO:005129710.024
microtubule based processGO:0007017600.024
proteasomal protein catabolic processGO:001049820.024
regulation of cellular ketone metabolic processGO:001056570.024
response to drugGO:004249330.024
digestive tract developmentGO:00485652650.024
cell surface receptor signaling pathwayGO:00071663250.024
regulation of nucleocytoplasmic transportGO:004682220.024
ubiquitin dependent protein catabolic processGO:000651130.024
cell morphogenesisGO:00009022890.024
cytoskeleton dependent cytokinesisGO:006164030.024
peptidyl lysine acetylationGO:001839420.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
positive regulation of cellular amine metabolic processGO:003324000.024
cellular amino acid metabolic processGO:000652070.023
regulation of response to stimulusGO:00485832690.023
rna export from nucleusGO:000640510.023
mitotic cell cycleGO:0000278640.023
cellular macromolecule biosynthetic processGO:00346452240.023
internal peptidyl lysine acetylationGO:001839320.023
regulation of mrna splicing via spliceosomeGO:004802430.023
nucleobase containing compound biosynthetic processGO:00346542050.023
regulation of nucleoside metabolic processGO:000911820.022
regulation of multicellular organismal processGO:00512392770.022
modification dependent protein catabolic processGO:001994130.022
growthGO:00400071740.022
eye developmentGO:00016542770.022
negative regulation of protein phosphorylationGO:000193340.022
cellular response to radiationGO:007147840.022
negative regulation of biological processGO:00485193040.022
positive regulation of biological processGO:00485182530.022
regulation of protein ubiquitinationGO:003139630.022
spindle assembly involved in mitosisGO:009030710.022
response to stressGO:00069502630.022
meiosis iGO:000712710.022
regulation of developmental processGO:00507932470.022
deathGO:00162651210.022
i kappab kinase nf kappab signalingGO:000724940.021
regulation of multicellular organismal developmentGO:20000262230.021
negative regulation of protein kinase activityGO:000646940.021
purine nucleoside monophosphate catabolic processGO:000912840.021
multi organism processGO:00517041340.021
nucleic acid transportGO:005065720.021
cell cycle g1 s phase transitionGO:004484310.021
regulation of macromolecule biosynthetic processGO:00105562250.021
organonitrogen compound metabolic processGO:1901564740.021
nucleoside monophosphate catabolic processGO:000912540.021
regulation of rho protein signal transductionGO:003502320.021
carboxylic acid metabolic processGO:0019752220.020
phagocytosis engulfmentGO:000691110.020
digestive system developmentGO:00551232890.020
regulation of gtp catabolic processGO:003312420.020
protein localization to plasma membraneGO:007265910.020
ribosomal small subunit biogenesisGO:004227420.020
regulation of metabolic processGO:00192223590.020
positive regulation of cytokine productionGO:000181920.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
regulation of protein complex assemblyGO:004325430.020
regulation of cell activationGO:005086510.019
positive regulation of nucleoside metabolic processGO:004597910.019
protein secretionGO:000930610.019
organic cyclic compound biosynthetic processGO:19013622230.019
microtubule organizing center organizationGO:003102310.019
regulation of dna replicationGO:000627530.019
regulation of biological qualityGO:00650082630.019
positive regulation of nucleotide catabolic processGO:003081310.019
cell cycleGO:0007049930.019
sensory organ developmentGO:00074233930.019
transcription from rna polymerase ii promoterGO:0006366800.019
regulation of purine nucleotide catabolic processGO:003312120.019
single organism metabolic processGO:00447102170.019
nuclear importGO:005117030.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
oxoacid metabolic processGO:0043436310.019
central nervous system developmentGO:00074173870.019
protein stabilizationGO:005082120.019
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.019
centrosome cycleGO:000709810.019
mitochondrion organizationGO:000700540.019
cell projection morphogenesisGO:00488582440.019
cellular protein metabolic processGO:00442671290.018
rna transportGO:005065820.018
generation of neuronsGO:00486993850.018
regulation of i kappab kinase nf kappab signalingGO:004312240.018
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
tissue remodelingGO:004877140.018
protein polymerizationGO:005125840.018
negative regulation of kinase activityGO:003367340.018
heterocycle biosynthetic processGO:00181302150.018
regulation of localizationGO:00328791040.018
brain developmentGO:00074202930.018
positive regulation of cellular processGO:00485222010.018
atp catabolic processGO:000620040.018
aromatic compound biosynthetic processGO:00194382170.018
regulation of reactive oxygen species metabolic processGO:200037720.018
regulation of neural precursor cell proliferationGO:200017730.018
double strand break repairGO:000630230.018
stem cell maintenanceGO:001982740.018
stem cell proliferationGO:007208940.018
g1 s transition of mitotic cell cycleGO:000008210.017
response to uvGO:000941130.017
digestive tract morphogenesisGO:00485462310.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
cytoskeleton organizationGO:0007010960.017
regulation of protein catabolic processGO:004217610.017
negative regulation of catabolic processGO:000989530.017
regulation of biosynthetic processGO:00098892500.017
programmed cell deathGO:00125011190.017
mitotic dna integrity checkpointGO:004477440.017
protein metabolic processGO:00195381830.017
positive regulation of gtp catabolic processGO:003312610.017
macromolecular complex subunit organizationGO:0043933740.017
fertilizationGO:000956630.017
ameboidal type cell migrationGO:00016671430.017
endosomal transportGO:001619720.017
regulation of cell developmentGO:00602841000.017
b cell activationGO:004211320.017
regulation of organ growthGO:004662030.017
regulation of signal transductionGO:00099662250.016
rna processingGO:0006396250.016
g2 dna damage checkpointGO:003157230.016
protein homooligomerizationGO:005126030.016
cellular nitrogen compound biosynthetic processGO:00442712180.016
regulation of autophagyGO:001050630.016
embryonic organ developmentGO:00485683810.016
membrane invaginationGO:001032410.016
nucleobase containing compound transportGO:001593120.016
regulation of nucleotide catabolic processGO:003081120.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
small molecule metabolic processGO:0044281770.016
cell part morphogenesisGO:00329902460.016
cognitionGO:005089010.016
centrosome duplicationGO:005129810.016
regulation of neuron differentiationGO:0045664560.016
mitotic dna damage checkpointGO:004477340.016
regulation of gtpase activityGO:004308720.016
regulation of signalingGO:00230512350.016
membrane fusionGO:006102520.016
dna templated transcription elongationGO:000635430.016
response to topologically incorrect proteinGO:003596620.016
sequestering of metal ionGO:005123830.016
developmental programmed cell deathGO:001062340.016
single organism membrane fusionGO:004480120.015
interspecies interaction between organismsGO:004441940.015
cellular protein modification processGO:00064641000.015
regulation of cellular component organizationGO:0051128860.015
establishment of rna localizationGO:005123630.015
macroautophagyGO:001623610.015
regulation of protein bindingGO:004339330.015
regulation of cellular biosynthetic processGO:00313262450.015
homeostatic processGO:00425921420.015
regulation of rna biosynthetic processGO:20011412130.015
embryonic organ morphogenesisGO:00485622740.015
regulation of neurogenesisGO:0050767870.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
mitotic cytokinesisGO:000028130.015
cellular carbohydrate metabolic processGO:004426240.015
primary neural tube formationGO:001402010.015
cell projection organizationGO:00300302840.015
cellular response to reactive oxygen speciesGO:003461420.015
cellular biosynthetic processGO:00442492860.015
regulation of cellular protein catabolic processGO:190336210.014
negative regulation of secretion by cellGO:190353120.014
positive regulation of macromolecule metabolic processGO:0010604930.014
system processGO:00030081850.014
microtubule cytoskeleton organization involved in mitosisGO:190285010.014
axon developmentGO:00615641660.014
response to organic substanceGO:00100331530.014
multi organism cellular processGO:004476420.014
macromolecule modificationGO:00434121110.014
positive regulation of apoptotic processGO:0043065290.014
negative regulation of cellular catabolic processGO:003133030.014
cell substrate adhesionGO:003158940.014
exocytosisGO:000688710.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
morphogenesis of an epitheliumGO:00020093330.014
regulation of jak stat cascadeGO:004642530.014
mitotic g2 dna damage checkpointGO:000709530.014
compound eye developmentGO:004874920.014
reproductive processGO:0022414400.014
response to glucoseGO:000974930.014
glucose homeostasisGO:004259310.014
organelle fusionGO:004828430.014
head developmentGO:00603223030.014
neuron differentiationGO:00301823530.014
positive regulation of chromatin modificationGO:190331010.013
regulation of nervous system developmentGO:0051960900.013
cellular response to chemical stimulusGO:00708871570.013
cell matrix adhesionGO:000716040.013
production of molecular mediator of immune responseGO:000244020.013
neuroblast proliferationGO:000740520.013
regionalizationGO:00030022740.013
positive regulation of cell deathGO:0010942290.013
regulation of transcription dna templatedGO:00063552130.013
carbohydrate biosynthetic processGO:001605110.013
negative regulation of cytokine productionGO:000181810.013
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.013
positive regulation of protein complex assemblyGO:003133420.013
response to carbohydrateGO:000974330.013
ribonucleotide metabolic processGO:0009259270.013
cell cycle g2 m phase transitionGO:004483940.013
cellular response to light stimulusGO:007148240.013
regulation of cell differentiationGO:00455951420.013
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.013
cellular respirationGO:004533330.013
positive regulation of metabolic processGO:00098931080.013
negative regulation of programmed cell deathGO:0043069580.013
cellular response to molecule of bacterial originGO:007121930.013
positive regulation of secretionGO:005104710.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
regulation of inflammatory responseGO:005072720.013
regulation of reproductive processGO:200024140.013
establishment of localization in cellGO:0051649770.013
cellular component morphogenesisGO:00329893360.013
anterior posterior pattern specificationGO:00099521520.013
leukocyte proliferationGO:007066110.013
rrna processingGO:000636470.013
protein modification processGO:00362111000.013
positive regulation of secretion by cellGO:190353210.013
negative regulation of dna metabolic processGO:005105340.012
regulation of stem cell proliferationGO:007209120.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
lymphocyte proliferationGO:004665110.012
alternative mrna splicing via spliceosomeGO:000038010.012
response to biotic stimulusGO:0009607970.012
blood vessel developmentGO:00015682460.012
carbohydrate homeostasisGO:003350010.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of cell cycleGO:0051726520.012
wnt signaling pathwayGO:0016055800.012
viral processGO:001603210.012
mononuclear cell proliferationGO:003294310.012
cell morphogenesis involved in differentiationGO:00009041950.012
segmentationGO:0035282970.012
negative regulation of signalingGO:0023057960.012
spermatid differentiationGO:004851520.012
positive regulation of cell adhesionGO:004578510.012
translational initiationGO:000641330.012
ras protein signal transductionGO:000726570.012
wound healingGO:0042060900.012
activation of mapk activityGO:000018730.012
retina development in camera type eyeGO:00600411460.012
positive regulation of cell divisionGO:005178120.012
organic acid metabolic processGO:0006082310.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
regulation of ras gtpase activityGO:003231820.012
regulation of organelle assemblyGO:190211540.012
negative regulation of apoptotic processGO:0043066550.012
response to woundingGO:00096111160.012
gland developmentGO:00487321430.012
somitogenesisGO:0001756870.012
cell migration involved in gastrulationGO:0042074790.012
negative regulation of protein transportGO:005122430.012
regenerationGO:0031099910.012
somatic muscle developmentGO:000752540.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
positive regulation of cytoskeleton organizationGO:005149530.012
organic substance transportGO:0071702580.012
mitotic g2 m transition checkpointGO:004481830.012
phosphate containing compound metabolic processGO:00067961080.012
mrna export from nucleusGO:000640610.011
positive regulation of dna templated transcription elongationGO:003278610.011
rna 3 end processingGO:003112320.011
camera type eye developmentGO:00430102220.011
positive regulation of translationGO:004572710.011
positive regulation of chromosome organizationGO:200125210.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
spermatid developmentGO:000728620.011
regulation of synapse organizationGO:005080730.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
protein dephosphorylationGO:000647030.011
secondary metabolic processGO:001974830.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
intracellular signal transductionGO:0035556850.011
negative regulation of chromosome organizationGO:200125110.011
transcription dna templatedGO:00063511810.011
positive regulation of histone modificationGO:003105810.011
peptide transportGO:001583310.011
regulation of cell communicationGO:00106462320.011
protein complex subunit organizationGO:0071822460.011
cell proliferationGO:0008283800.011
negative regulation of cell deathGO:0060548600.011
response to corticosteroidGO:003196010.011
sensory organ morphogenesisGO:00905962000.011
mitochondrial transportGO:000683920.011
cell cycle arrestGO:000705010.011
negative regulation of secretionGO:005104820.011
cellular response to topologically incorrect proteinGO:003596720.011
regulation of carbohydrate metabolic processGO:000610940.011
negative regulation of signal transductionGO:0009968940.011
gastrulationGO:00073692080.011
hemopoiesisGO:00300971830.011
cellular amide metabolic processGO:004360340.011
erk1 and erk2 cascadeGO:007037140.011
positive regulation of inflammatory responseGO:005072910.011
negative regulation of cell communicationGO:0010648960.011
mrna 3 end processingGO:003112420.011
negative regulation of nuclear divisionGO:005178430.011
chemosensory behaviorGO:000763510.011
extrinsic apoptotic signaling pathwayGO:009719130.011
establishment of protein localization to plasma membraneGO:009000210.011
neuron developmentGO:00486662620.011
striated muscle tissue developmentGO:00147061100.011
neurotransmitter transportGO:000683620.011
regulation of muscle contractionGO:000693730.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
mesoderm developmentGO:0007498880.011
regulation of dna templated transcription elongationGO:003278430.011
positive regulation of map kinase activityGO:004340630.011
macromolecular complex disassemblyGO:003298410.011
regulation of response to biotic stimulusGO:000283120.011
negative regulation of sequestering of calcium ionGO:005128340.011
female meiotic divisionGO:000714320.010
skin developmentGO:0043588540.010
regulation of blood pressureGO:000821710.010
regulation of stem cell differentiationGO:200073640.010
convergent extensionGO:00600261180.010
adult behaviorGO:003053420.010
positive regulation of cell activationGO:005086710.010
canonical wnt signaling pathwayGO:0060070480.010
tube closureGO:006060610.010
protein complex disassemblyGO:004324110.010
response to monosaccharideGO:003428430.010
organelle fissionGO:0048285230.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.010
regulation of cellular component movementGO:0051270550.010
regulation of anatomical structure morphogenesisGO:00226031300.010
intracellular transportGO:0046907320.010
small gtpase mediated signal transductionGO:000726480.010
alcohol biosynthetic processGO:004616520.010
locomotor rhythmGO:004547530.010
small molecule catabolic processGO:004428230.010
mrna transportGO:005102820.010

twistnb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
disease of anatomical entityDOID:700.011
organ system cancerDOID:005068600.010