Danio rerio

34 known processes

dysf

dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)

(Aliases: fb73b05,si:rp71-50c18.1,wu:fb73b05)

dysf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism metabolic processGO:00447102170.201
negative regulation of biological processGO:00485193040.192
cell projection organizationGO:00300302840.176
response to stressGO:00069502630.159
embryonic organ developmentGO:00485683810.150
establishment of localizationGO:00512342440.128
cell surface receptor signaling pathwayGO:00071663250.111
embryo development ending in birth or egg hatchingGO:00097922710.109
regulation of multicellular organismal processGO:00512392770.108
agingGO:000756820.107
actomyosin structure organizationGO:0031032530.102
immune system processGO:00023762410.097
regulation of cellular metabolic processGO:00313233200.091
blood circulationGO:0008015870.089
cell part morphogenesisGO:00329902460.089
cellular component movementGO:00069283350.088
regulation of response to stimulusGO:00485832690.085
regulation of primary metabolic processGO:00800903110.085
cellular nitrogen compound metabolic processGO:00346412900.085
regulation of protein complex assemblyGO:004325430.084
striated muscle cell developmentGO:00550021080.080
multicellular organism growthGO:003526440.078
larval developmentGO:000216420.078
protein localization to nucleusGO:003450430.074
cellular amide metabolic processGO:004360340.073
regulation of metabolic processGO:00192223590.072
regulation of cytoplasmic transportGO:190364940.071
regulation of protein localization to nucleusGO:190018020.070
regulation of protein transportGO:005122330.062
cell migrationGO:00164772370.062
organelle organizationGO:00069962270.058
cellular component morphogenesisGO:00329893360.058
cell projection morphogenesisGO:00488582440.056
negative regulation of cellular processGO:00485232830.054
spermatid developmentGO:000728620.054
system processGO:00030081850.052
cellular component assembly involved in morphogenesisGO:00109271070.052
regulation of multicellular organism growthGO:004001440.050
muscle cell differentiationGO:00426921390.049
heart contractionGO:0060047710.049
organonitrogen compound metabolic processGO:1901564740.049
heart developmentGO:00075073130.047
cell morphogenesisGO:00009022890.047
regulation of locomotionGO:0040012550.046
regulation of establishment of protein localizationGO:007020140.046
regulation of protein import into nucleusGO:004230620.045
secondary metabolic processGO:001974830.045
nuclear transportGO:005116940.045
regulation of intracellular protein transportGO:003315730.044
protein import into nucleusGO:000660630.044
organic acid metabolic processGO:0006082310.044
organic cyclic compound metabolic processGO:19013603010.043
signal transductionGO:00071654550.043
regulation of cytokine productionGO:000181730.042
regulation of biological qualityGO:00650082630.042
cellular response to oxygen levelsGO:007145310.041
regulation of macromolecule metabolic processGO:00602553170.041
establishment of protein localization to organelleGO:007259440.040
central nervous system developmentGO:00074173870.040
oxoacid metabolic processGO:0043436310.040
long chain fatty acid metabolic processGO:000167610.039
gene expressionGO:00104672520.039
cell substrate adhesionGO:003158940.039
programmed cell deathGO:00125011190.038
generation of neuronsGO:00486993850.038
sensory organ morphogenesisGO:00905962000.038
circulatory system processGO:0003013870.038
stem cell maintenanceGO:001982740.037
striated muscle cell differentiationGO:00511461290.037
stem cell differentiationGO:00488631170.037
regulation of protein catabolic processGO:004217610.037
negative regulation of cytoplasmic transportGO:190365020.037
nitrogen compound metabolic processGO:00068073190.037
immune system developmentGO:00025201910.037
locomotionGO:00400113130.036
somite developmentGO:0061053960.036
collagen metabolic processGO:003296320.036
skeletal system morphogenesisGO:00487051020.036
muscle cell developmentGO:00550011150.036
multicellular organismal metabolic processGO:004423620.035
single organism transportGO:00447652060.035
cell matrix adhesionGO:000716040.035
positive regulation of transportGO:005105020.035
circadian sleep wake cycle processGO:002241020.034
regulation of cell projection assemblyGO:006049140.034
striated muscle tissue developmentGO:00147061100.034
carboxylic acid metabolic processGO:0019752220.033
negative regulation of protein localization to nucleusGO:190018120.033
negative regulation of metabolic processGO:0009892860.033
ubiquitin dependent protein catabolic processGO:000651130.033
macromolecule modificationGO:00434121110.032
regulation of cellular amine metabolic processGO:003323800.032
positive regulation of biological processGO:00485182530.032
regulation of immune system processGO:0002682340.032
regulation of protein targetingGO:190353320.031
positive regulation of cytokine productionGO:000181920.031
regulation of nitrogen compound metabolic processGO:00511712510.031
protein metabolic processGO:00195381830.031
nucleocytoplasmic transportGO:000691340.030
post embryonic morphogenesisGO:000988640.030
cell morphogenesis involved in neuron differentiationGO:00486671630.030
vasculature developmentGO:00019442780.030
response to topologically incorrect proteinGO:003596620.030
cellular aromatic compound metabolic processGO:00067252950.030
autophagyGO:000691440.029
circadian sleep wake cycle sleepGO:005080210.029
regulation of circadian sleep wake cycleGO:004274910.029
myofibril assemblyGO:0030239480.029
axon guidanceGO:0007411860.028
regulation of cell migrationGO:0030334400.028
response to chemicalGO:00422213200.028
negative regulation of catabolic processGO:000989530.028
i kappab kinase nf kappab signalingGO:000724940.028
response to oxygen levelsGO:0070482250.028
sarcomere organizationGO:0045214260.028
cellular protein catabolic processGO:004425740.027
long chain fatty acid transportGO:001590910.027
transportGO:00068102200.027
embryonic skeletal system developmentGO:0048706970.027
axonogenesisGO:00074091520.027
protein targeting to nucleusGO:004474430.026
regulation of nucleocytoplasmic transportGO:004682220.026
regulation of bindingGO:005109830.026
modification dependent macromolecule catabolic processGO:004363230.026
regulation of dendrite developmentGO:005077330.026
somitogenesisGO:0001756870.025
taxisGO:00423301090.025
heart processGO:0003015710.025
carbohydrate biosynthetic processGO:001605110.025
regulation of nucleotide catabolic processGO:003081120.025
growthGO:00400071740.025
nuclear importGO:005117030.024
response to decreased oxygen levelsGO:0036293250.024
circadian sleep wake cycleGO:004274520.024
amine metabolic processGO:000930820.024
chordate embryonic developmentGO:00430092710.024
cell morphogenesis involved in differentiationGO:00009041950.024
cellular macromolecule metabolic processGO:00442603910.024
positive regulation of cell cycleGO:004578730.023
neuron developmentGO:00486662620.023
response to external stimulusGO:00096052640.023
regulation of cellular amino acid metabolic processGO:000652100.023
organic substance transportGO:0071702580.023
cellular response to stressGO:0033554620.023
internal protein amino acid acetylationGO:000647520.023
nucleobase containing compound metabolic processGO:00061392740.023
protein activation cascadeGO:007237660.023
cell motilityGO:00488702440.023
purine nucleoside monophosphate catabolic processGO:000912840.023
heterocycle metabolic processGO:00464832900.023
response to abiotic stimulusGO:00096281220.023
rna metabolic processGO:00160702190.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
regulation of cell motilityGO:2000145460.022
multicellular organismal macromolecule metabolic processGO:004425920.022
negative regulation of macromolecule metabolic processGO:0010605760.022
response to woundingGO:00096111160.022
immune effector processGO:0002252230.022
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.022
cellular amino acid metabolic processGO:000652070.022
regulation of cellular ketone metabolic processGO:001056570.022
regulation of transcription dna templatedGO:00063552130.021
negative regulation of signalingGO:0023057960.021
chromosome organizationGO:0051276310.021
phosphate containing compound metabolic processGO:00067961080.021
blood vessel developmentGO:00015682460.021
protein heterooligomerizationGO:005129110.021
peptide metabolic processGO:000651810.021
positive regulation of immune effector processGO:000269930.021
cytoskeleton organizationGO:0007010960.021
proteolysisGO:0006508380.021
single organism nuclear importGO:190259330.020
chemotaxisGO:00069351040.020
regulation of stem cell differentiationGO:200073640.020
skeletal system developmentGO:00015011810.020
cellular amine metabolic processGO:004410620.020
ameboidal type cell migrationGO:00016671430.020
carbohydrate homeostasisGO:003350010.020
negative regulation of protein transportGO:005122430.020
nucleic acid metabolic processGO:00903042440.020
protein acetylationGO:000647320.020
axon developmentGO:00615641660.020
negative regulation of intracellular transportGO:003238730.020
negative regulation of intracellular protein transportGO:009031730.019
negative regulation of nucleocytoplasmic transportGO:004682320.019
heterocycle biosynthetic processGO:00181302150.019
negative regulation of mitosisGO:004583930.019
localization of cellGO:00516742440.019
organelle assemblyGO:00709251100.019
positive regulation of response to stimulusGO:0048584800.019
synaptic growth at neuromuscular junctionGO:005112420.019
positive regulation of cellular component biogenesisGO:004408930.019
modification dependent protein catabolic processGO:001994130.019
positive regulation of cellular processGO:00485222010.019
negative regulation of cellular catabolic processGO:003133030.019
regulation of inflammatory responseGO:005072720.018
skeletal muscle tissue developmentGO:0007519670.018
proteasomal protein catabolic processGO:001049820.018
mononuclear cell proliferationGO:003294310.018
intracellular signal transductionGO:0035556850.018
response to carbohydrateGO:000974330.017
negative regulation of myeloid cell differentiationGO:004563810.017
cellular response to decreased oxygen levelsGO:003629410.017
negative regulation of response to stimulusGO:00485851040.017
muscle structure developmentGO:00610611960.017
cellular component biogenesisGO:00440851780.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
glucose importGO:004632320.017
head developmentGO:00603223030.017
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.017
regulation of peptidase activityGO:0052547230.017
cellular response to hypoxiaGO:007145610.017
hemopoiesisGO:00300971830.017
protein acylationGO:004354330.016
sprouting angiogenesisGO:0002040530.016
cellular ketone metabolic processGO:0042180110.016
cellular carbohydrate metabolic processGO:004426240.016
spermatid differentiationGO:004851520.016
regulation of protein bindingGO:004339330.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
small molecule metabolic processGO:0044281770.016
ovulation cycle processGO:002260220.016
cell deathGO:00082191210.016
brain developmentGO:00074202930.016
negative regulation of cytokine productionGO:000181810.016
digestive tract morphogenesisGO:00485462310.016
mechanosensory behaviorGO:000763820.016
protein modification processGO:00362111000.016
neuron projection developmentGO:00311751800.016
antimicrobial humoral responseGO:001973020.016
centrosome organizationGO:005129710.016
aorta developmentGO:003590440.016
female gonad developmentGO:000858540.016
regulation of cell activationGO:005086510.016
development of primary female sexual characteristicsGO:004654540.016
regionalizationGO:00030022740.015
embryonic limb morphogenesisGO:003032620.015
regulation of cellular component movementGO:0051270550.015
single organism localizationGO:19025782250.015
transcription dna templatedGO:00063511810.015
regulation of autophagyGO:001050630.015
negative regulation of protein phosphorylationGO:000193340.015
defense responseGO:0006952470.015
sensory perception of chemical stimulusGO:000760630.015
energy reserve metabolic processGO:000611220.015
single organism organelle organizationGO:19025891990.015
regulation of cell communicationGO:00106462320.015
maintenance of locationGO:005123540.015
sensory system developmentGO:0048880760.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
apoptotic processGO:00069151160.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
positive regulation of stem cell proliferationGO:200064810.015
neuron projection morphogenesisGO:00488121610.015
myotube differentiationGO:0014902450.015
regulation of programmed cell deathGO:00430671010.015
regulation of multicellular organismal developmentGO:20000262230.015
muscle attachmentGO:001620390.015
stem cell proliferationGO:007208940.015
carboxylic acid catabolic processGO:004639530.015
embryonic skeletal system morphogenesisGO:0048704930.015
positive regulation of cell activationGO:005086710.015
negative regulation of protein import into nucleusGO:004230820.015
cellular localizationGO:0051641970.015
regulation of circadian rhythmGO:004275240.014
morphogenesis of an epitheliumGO:00020093330.014
lipid catabolic processGO:001604240.014
regulation of circadian sleep wake cycle sleepGO:004518710.014
single organism cellular localizationGO:1902580460.014
peptidyl lysine acetylationGO:001839420.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
regulation of tube sizeGO:003515020.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
cellular component assemblyGO:00226071700.014
cellular response to external stimulusGO:007149620.014
ovulation cycleGO:004269820.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
somatic stem cell maintenanceGO:003501910.013
regulation of cytokine mediated signaling pathwayGO:000195930.013
regulation of cellular protein catabolic processGO:190336210.013
regulation of proteolysisGO:0030162240.013
regulation of nucleoside metabolic processGO:000911820.013
positive regulation of secretionGO:005104710.013
protein polymerizationGO:005125840.013
cellular biosynthetic processGO:00442492860.013
glucose homeostasisGO:004259310.013
smooth muscle contractionGO:000693920.013
meiotic nuclear divisionGO:000712640.013
lymphocyte proliferationGO:004665110.013
protein importGO:001703830.013
response to monosaccharideGO:003428430.013
cell cycle arrestGO:000705010.013
muscle tissue developmentGO:00605371100.013
regulation of purine nucleotide catabolic processGO:003312120.013
response to hexoseGO:000974630.013
cell proliferationGO:0008283800.013
directional locomotionGO:003305810.013
actin cytoskeleton organizationGO:0030036630.012
positive regulation of secretion by cellGO:190353210.012
myeloid cell differentiationGO:0030099860.012
trabecula morphogenesisGO:006138320.012
cell migration involved in gastrulationGO:0042074790.012
negative regulation of cellular metabolic processGO:0031324770.012
skeletal muscle organ developmentGO:0060538780.012
phosphorylationGO:0016310690.012
indole containing compound metabolic processGO:004243020.012
response to hypoxiaGO:0001666250.012
fatty acid transportGO:001590810.012
cytokinesisGO:000091030.012
female sex differentiationGO:004666040.012
extracellular matrix assemblyGO:008502910.012
cellular protein modification processGO:00064641000.012
developmental programmed cell deathGO:001062340.012
regulation of signal transductionGO:00099662250.012
response to hydrogen peroxideGO:004254230.012
cilium organizationGO:0044782710.012
peptidyl serine modificationGO:001820920.012
regulation of reproductive processGO:200024140.012
regulation of developmental processGO:00507932470.012
embryonic skeletal joint developmentGO:007249830.012
positive regulation of cellular amine metabolic processGO:003324000.012
regenerationGO:0031099910.012
negative regulation of mapk cascadeGO:004340940.012
single organism reproductive processGO:0044702400.012
peptide transportGO:001583310.012
positive regulation of cellular catabolic processGO:003133130.012
positive regulation of protein complex assemblyGO:003133420.012
somatic muscle developmentGO:000752540.012
wnt signaling pathwayGO:0016055800.012
neuron differentiationGO:00301823530.012
regulation of localizationGO:00328791040.012
positive regulation of catabolic processGO:000989640.012
cellular protein metabolic processGO:00442671290.011
fatty acid biosynthetic processGO:000663340.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
neuron projection guidanceGO:0097485860.011
mrna stabilizationGO:004825540.011
single organism biosynthetic processGO:0044711710.011
response to endogenous stimulusGO:0009719830.011
phosphorus metabolic processGO:00067931090.011
positive regulation of cellular carbohydrate metabolic processGO:001067610.011
negative regulation of protein kinase b signalingGO:005189820.011
neurotransmitter transportGO:000683620.011
digestive system developmentGO:00551232890.011
blood vessel morphogenesisGO:00485142160.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
alpha amino acid metabolic processGO:190160530.011
regulation of protein metabolic processGO:0051246560.011
neuromast developmentGO:0048884460.011
camera type eye developmentGO:00430102220.011
organic substance biosynthetic processGO:19015762890.011
germ line stem cell maintenanceGO:003071820.011
glial cell migrationGO:000834730.011
regulation of phosphorus metabolic processGO:0051174430.011
sensory organ developmentGO:00074233930.011
regulation of neural precursor cell proliferationGO:200017730.011
axon extensionGO:0048675450.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
regulation of apoptotic processGO:0042981980.011
tube morphogenesisGO:00352393490.011
cellular catabolic processGO:0044248270.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
rna biosynthetic processGO:00327741810.010
leukocyte proliferationGO:007066110.010
positive regulation of signal transductionGO:0009967560.010
nucleic acid templated transcriptionGO:00976591810.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010
negative regulation of immune responseGO:005077720.010
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.010
eye developmentGO:00016542770.010
regulation of dendrite morphogenesisGO:004881430.010
internal peptidyl lysine acetylationGO:001839320.010
neuromuscular synaptic transmissionGO:000727420.010
retinal ganglion cell axon guidanceGO:0031290350.010
catabolic processGO:0009056320.010
positive regulation of dna metabolic processGO:005105410.010
developmental cell growthGO:0048588520.010
sex determinationGO:000753010.010
positive regulation of neural precursor cell proliferationGO:200017910.010
b cell mediated immunityGO:001972430.010
regulation of epithelial cell proliferationGO:005067830.010
enzyme linked receptor protein signaling pathwayGO:00071671060.010
response to corticosteroidGO:003196010.010
actin filament based processGO:0030029640.010
dna templated transcription initiationGO:000635210.010
membrane fusionGO:006102520.010

dysf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.024
organ system cancerDOID:005068600.018
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
disease of anatomical entityDOID:700.017
musculoskeletal system diseaseDOID:1700.017
nervous system diseaseDOID:86300.014
cardiovascular system diseaseDOID:128700.013