Danio rerio

0 known processes

hibadha

3-hydroxyisobutyrate dehydrogenase a

(Aliases: wu:fb07f02,zgc:100804)

hibadha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nitrogen compound metabolic processGO:00068073190.131
organic cyclic compound metabolic processGO:19013603010.096
cellular biosynthetic processGO:00442492860.094
cellular aromatic compound metabolic processGO:00067252950.081
cellular nitrogen compound metabolic processGO:00346412900.077
regulation of cellular carbohydrate metabolic processGO:001067540.073
heterocycle metabolic processGO:00464832900.073
cellular ketone metabolic processGO:0042180110.066
regulation of macromolecule metabolic processGO:00602553170.065
cellular macromolecule metabolic processGO:00442603910.064
protein modification processGO:00362111000.062
regulation of transcription dna templatedGO:00063552130.061
cellular nitrogen compound biosynthetic processGO:00442712180.060
positive regulation of catabolic processGO:000989640.054
regulation of nitrogen compound metabolic processGO:00511712510.054
regulation of primary metabolic processGO:00800903110.053
negative regulation of biological processGO:00485193040.052
biosynthetic processGO:00090582940.051
rna biosynthetic processGO:00327741810.048
regulation of transcription from rna polymerase ii promoterGO:00063571140.047
apoptotic process involved in morphogenesisGO:006056120.046
negative regulation of gene expressionGO:0010629650.046
nucleic acid templated transcriptionGO:00976591810.045
aromatic compound biosynthetic processGO:00194382170.045
organic substance biosynthetic processGO:19015762890.045
regulation of multicellular organism growthGO:004001440.045
larval developmentGO:000216420.044
tube morphogenesisGO:00352393490.043
medulla oblongata developmentGO:002155040.043
phagocytosisGO:000690930.042
regulation of biosynthetic processGO:00098892500.042
lipid storageGO:001991510.042
cognitionGO:005089010.040
regulation of cellular macromolecule biosynthetic processGO:20001122220.040
positive regulation of biological processGO:00485182530.039
positive regulation of cell cycleGO:004578730.039
single organism metabolic processGO:00447102170.039
morphogenesis of an epitheliumGO:00020093330.038
nucleobase containing compound biosynthetic processGO:00346542050.038
negative regulation of cellular processGO:00485232830.038
digestive tract morphogenesisGO:00485462310.038
regulation of cellular biosynthetic processGO:00313262450.038
embryonic skeletal joint developmentGO:007249830.036
endothelial cell fate commitmentGO:006083930.035
cellular carbohydrate metabolic processGO:004426240.035
guanosine containing compound metabolic processGO:190106840.035
signal transductionGO:00071654550.035
regulation of blood vessel sizeGO:005088020.035
positive regulation of cellular processGO:00485222010.035
cell projection organizationGO:00300302840.034
positive regulation of cellular component biogenesisGO:004408930.034
macromolecule biosynthetic processGO:00090592270.034
cell morphogenesis involved in differentiationGO:00009041950.033
regulation of carbohydrate metabolic processGO:000610940.033
heterocycle biosynthetic processGO:00181302150.033
regulation of metabolic processGO:00192223590.033
regulation of tube sizeGO:003515020.033
cell morphogenesisGO:00009022890.033
cellular component morphogenesisGO:00329893360.032
negative regulation of protein phosphorylationGO:000193340.032
regulation of developmental processGO:00507932470.032
septum transversum developmentGO:000334340.032
maintenance of locationGO:005123540.032
regulation of gene expressionGO:00104682650.031
digestive system developmentGO:00551232890.031
sensory organ developmentGO:00074233930.031
regulation of cellular amine metabolic processGO:003323800.031
regulation of chondrocyte differentiationGO:003233010.031
gene expressionGO:00104672520.030
organonitrogen compound metabolic processGO:1901564740.030
regulation of cellular metabolic processGO:00313233200.030
amine metabolic processGO:000930820.029
adult behaviorGO:003053420.029
regulation of rna metabolic processGO:00512522240.028
apoptotic process involved in developmentGO:190274220.028
single organism localizationGO:19025782250.028
mesoderm developmentGO:0007498880.028
cellular macromolecule biosynthetic processGO:00346452240.028
central nervous system developmentGO:00074173870.027
regulation of biomineral tissue developmentGO:007016720.027
nitric oxide metabolic processGO:004620920.027
head developmentGO:00603223030.027
organic cyclic compound biosynthetic processGO:19013622230.027
energy reserve metabolic processGO:000611220.027
regulation of multicellular organismal developmentGO:20000262230.027
negative regulation of synapse assemblyGO:005196420.027
cell migrationGO:00164772370.026
actin polymerization or depolymerizationGO:000815420.026
reactive nitrogen species metabolic processGO:200105700.026
astrocyte differentiationGO:004870810.026
nephron tubule morphogenesisGO:007207810.026
regulation of cellular ketone metabolic processGO:001056570.026
carboxylic acid metabolic processGO:0019752220.025
regulation of multicellular organismal processGO:00512392770.025
cell surface receptor signaling pathwayGO:00071663250.025
digestive tract developmentGO:00485652650.025
response to chemicalGO:00422213200.025
regulation of glucose transportGO:001082710.025
cellular protein modification processGO:00064641000.025
oxoacid metabolic processGO:0043436310.025
positive regulation of transportGO:005105020.025
vasculature developmentGO:00019442780.025
extrinsic apoptotic signaling pathwayGO:009719130.025
response to stressGO:00069502630.025
cell fate specificationGO:0001708680.024
regulation of protein catabolic processGO:004217610.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
retina development in camera type eyeGO:00600411460.024
nucleic acid metabolic processGO:00903042440.024
forebrain developmentGO:0030900960.024
gtp metabolic processGO:004603940.024
regulation of nucleic acid templated transcriptionGO:19035062130.024
small molecule metabolic processGO:0044281770.023
carbohydrate biosynthetic processGO:001605110.023
hormone transportGO:000991420.023
transcription dna templatedGO:00063511810.023
fin regenerationGO:0031101510.023
positive regulation of cell divisionGO:005178120.023
negative chemotaxisGO:005091910.023
protein localization to nucleusGO:003450430.023
autophagyGO:000691440.023
regulation of response to stimulusGO:00485832690.023
mitotic cell cycleGO:0000278640.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
pericardium developmentGO:006003910.023
single organism organelle organizationGO:19025891990.023
positive regulation of glucose transportGO:001082810.023
transcription from rna polymerase ii promoterGO:0006366800.023
agingGO:000756820.022
response to woundingGO:00096111160.022
rna metabolic processGO:00160702190.022
regulation of glucose importGO:004632410.022
proteolysis involved in cellular protein catabolic processGO:005160330.022
growthGO:00400071740.022
developmental growthGO:00485891660.022
deathGO:00162651210.022
cellular protein metabolic processGO:00442671290.022
hormone secretionGO:004687920.022
stem cell proliferationGO:007208940.022
phosphorylationGO:0016310690.022
leukocyte proliferationGO:007066110.022
female sex differentiationGO:004666040.021
embryonic organ morphogenesisGO:00485622740.021
locomotionGO:00400113130.021
somatic muscle developmentGO:000752540.021
brain developmentGO:00074202930.021
regulation of blood pressureGO:000821710.021
cell motilityGO:00488702440.021
regulation of signalingGO:00230512350.021
germ line stem cell divisionGO:004207810.020
determination of bilateral symmetryGO:00098552040.020
regulation of cell activationGO:005086510.020
ubiquitin dependent protein catabolic processGO:000651130.020
regulation of reproductive processGO:200024140.020
secondary metabolic processGO:001974830.020
gtp catabolic processGO:000618420.020
embryonic limb morphogenesisGO:003032620.020
lateral inhibitionGO:004633110.020
homeostatic processGO:00425921420.020
positive regulation of cellular catabolic processGO:003133130.020
modification dependent macromolecule catabolic processGO:004363230.020
macromolecule modificationGO:00434121110.020
guanosine containing compound catabolic processGO:190106920.020
regulation of reactive oxygen species metabolic processGO:200037720.020
regulation of rna biosynthetic processGO:20011412130.019
cellular response to external stimulusGO:007149620.019
multicellular organism growthGO:003526440.019
negative regulation of macromolecule metabolic processGO:0010605760.019
angiogenesisGO:00015251580.019
regulation of stem cell differentiationGO:200073640.019
regulation of synapse assemblyGO:005196330.019
regulation of protein complex assemblyGO:004325430.019
cellular amine metabolic processGO:004410620.019
porphyrin containing compound metabolic processGO:0006778100.019
regulation of receptor mediated endocytosisGO:004825940.019
regenerationGO:0031099910.019
protein metabolic processGO:00195381830.019
blood vessel morphogenesisGO:00485142160.019
regionalizationGO:00030022740.018
gastrulationGO:00073692080.018
positive regulation of nucleoside metabolic processGO:004597910.018
positive regulation of dna metabolic processGO:005105410.018
activation of mapk activityGO:000018730.018
adherens junction organizationGO:003433240.018
invagination involved in gastrulation with mouth forming secondGO:005510910.018
organic acid metabolic processGO:0006082310.018
blood vessel developmentGO:00015682460.018
gastrulation with mouth forming secondGO:0001702440.018
pericardium morphogenesisGO:000334410.018
positive regulation of metabolic processGO:00098931080.018
nephron morphogenesisGO:007202820.018
proteasomal protein catabolic processGO:001049820.018
nucleobase containing compound metabolic processGO:00061392740.018
regulation of synapse organizationGO:005080730.018
regulation of cell shapeGO:000836010.018
regulation of signal transductionGO:00099662250.018
multicellular organismal metabolic processGO:004423620.017
regulation of cellular amino acid metabolic processGO:000652100.017
dorsal motor nucleus of vagus nerve developmentGO:002174440.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
regulation of dna replicationGO:000627530.017
regulation of cell communicationGO:00106462320.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
regulation of protein transportGO:005122330.017
regulation of nucleoside metabolic processGO:000911820.017
immune system processGO:00023762410.017
regulation of hormone secretionGO:004688320.017
cell cycleGO:0007049930.017
heart valve formationGO:000318840.017
regulation of protein targetingGO:190353320.016
proepicardium developmentGO:000334240.016
regulation of organ growthGO:004662030.016
regulation of biological qualityGO:00650082630.016
phosphorus metabolic processGO:00067931090.016
single fertilizationGO:000733830.016
regulation of bindingGO:005109830.016
response to uvGO:000941130.016
urogenital system developmentGO:0001655970.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.016
response to corticosteroidGO:003196010.016
synaptic growth at neuromuscular junctionGO:005112420.016
membrane fusionGO:006102520.016
regulation of sodium ion transportGO:000202820.016
positive regulation of muscle organ developmentGO:004863610.016
ventricular cardiac muscle tissue developmentGO:000322930.016
regulation of establishment of protein localizationGO:007020140.016
tissue regenerationGO:0042246740.016
internal protein amino acid acetylationGO:000647520.016
behaviorGO:0007610740.016
positive regulation of positive chemotaxisGO:005092740.016
regulation of transporter activityGO:003240920.016
cellular component movementGO:00069283350.016
epithelial cell differentiationGO:00308551160.016
ribonucleoside monophosphate catabolic processGO:000915840.016
golgi vesicle transportGO:004819330.016
renal tubule morphogenesisGO:006133310.016
developmental pigmentationGO:0048066480.016
cellular amino acid metabolic processGO:000652070.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
negative regulation of metabolic processGO:0009892860.016
cell projection morphogenesisGO:00488582440.016
cell substrate adhesionGO:003158940.016
developmental programmed cell deathGO:001062340.016
protein polymerizationGO:005125840.016
hemopoiesisGO:00300971830.016
heart developmentGO:00075073130.016
positive regulation of nucleotide catabolic processGO:003081310.016
monocarboxylic acid catabolic processGO:007232930.016
neuroblast proliferationGO:000740520.016
peptidyl lysine acetylationGO:001839420.016
regulation of cell projection assemblyGO:006049140.016
mononuclear cell proliferationGO:003294310.015
muscle structure developmentGO:00610611960.015
retinal rod cell developmentGO:004654840.015
positive regulation of macromolecule metabolic processGO:0010604930.015
hematopoietic or lymphoid organ developmentGO:00485341910.015
system processGO:00030081850.015
determination of left right symmetryGO:00073681790.015
regulation of macromolecule biosynthetic processGO:00105562250.015
signal transduction in absence of ligandGO:003803410.015
single organism biosynthetic processGO:0044711710.015
regulation of autophagyGO:001050630.015
sensory organ morphogenesisGO:00905962000.015
negative regulation of ras protein signal transductionGO:004658010.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
regulation of metal ion transportGO:001095940.015
photoreceptor cell fate specificationGO:004370410.015
receptor internalizationGO:003162320.015
cellular modified amino acid metabolic processGO:000657530.015
cellular component disassemblyGO:002241110.015
modification dependent protein catabolic processGO:001994130.015
protein localization to plasma membraneGO:007265910.015
positive regulation of map kinase activityGO:004340630.015
regulation of oocyte developmentGO:006028130.015
pathway restricted smad protein phosphorylationGO:006038910.015
convergent extensionGO:00600261180.015
reactive oxygen species biosynthetic processGO:190340910.015
regulation of nucleotide catabolic processGO:003081120.015
glucose importGO:004632320.015
regulation of endothelial cell proliferationGO:000193610.015
camera type eye developmentGO:00430102220.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
cell matrix adhesionGO:000716040.015
positive regulation of secretionGO:005104710.015
alpha amino acid metabolic processGO:190160530.015
g1 s transition of mitotic cell cycleGO:000008210.015
cellular response to oxygen levelsGO:007145310.014
cellular protein catabolic processGO:004425740.014
embryonic skeletal joint morphogenesisGO:006027230.014
regulation of apoptotic processGO:0042981980.014
meiosis iGO:000712710.014
negative regulation of chemotaxisGO:005092240.014
protein heterooligomerizationGO:005129110.014
cellular response to light stimulusGO:007148240.014
meiotic nuclear divisionGO:000712640.014
positive regulation of epithelial cell differentiationGO:003085820.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
heme metabolic processGO:004216890.014
response to fluid shear stressGO:003440520.014
cell cycle g1 s phase transitionGO:004484310.014
stem cell divisionGO:001714510.014
negative regulation of kinase activityGO:003367340.014
regulation of filopodium assemblyGO:005148920.014
regulation of dna templated transcription in response to stressGO:004362000.014
regulation of lipid transportGO:003236840.014
regulation of cell deathGO:00109411030.014
nucleoside monophosphate catabolic processGO:000912540.014
phosphate containing compound metabolic processGO:00067961080.014
oocyte maturationGO:000155640.014
lymphocyte proliferationGO:004665110.014
regulation of cell differentiationGO:00455951420.014
regulation of bone mineralizationGO:003050020.014
positive regulation of glucose importGO:004632610.014
immune system developmentGO:00025201910.013
lipid catabolic processGO:001604240.013
regulation of cell substrate adhesionGO:001081010.013
regulation of anatomical structure morphogenesisGO:00226031300.013
neurotransmitter transportGO:000683620.013
specification of symmetryGO:00097992040.013
establishment of localizationGO:00512342440.013
positive regulation of cytoskeleton organizationGO:005149530.013
compound eye developmentGO:004874920.013
positive regulation of cellular metabolic processGO:0031325940.013
regulation of neuron differentiationGO:0045664560.013
cellular response to nutrient levelsGO:003166920.013
endocrine processGO:005088620.013
organelle organizationGO:00069962270.013
negative regulation of protein kinase activityGO:000646940.013
regulation of gtpase activityGO:004308720.013
positive regulation of cellular amine metabolic processGO:003324000.013
regulation of epithelial cell proliferationGO:005067830.013
regulation of purine nucleotide catabolic processGO:003312120.013
nuclear transportGO:005116940.013
negative regulation of rna metabolic processGO:0051253480.013
neuron developmentGO:00486662620.013
positive regulation of carbohydrate metabolic processGO:004591310.013
regulation of dendrite developmentGO:005077330.012
negative regulation of catabolic processGO:000989530.012
insulin like growth factor receptor signaling pathwayGO:004800940.012
pronephros morphogenesisGO:0072114140.012
regulation of carbohydrate biosynthetic processGO:004325510.012
protein acetylationGO:000647320.012
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.012
convergent extension involved in gastrulationGO:0060027710.012
negative regulation of muscle tissue developmentGO:190186220.012
cell deathGO:00082191210.012
negative regulation of protein transportGO:005122430.012
atp catabolic processGO:000620040.012
positive regulation of biosynthetic processGO:0009891680.012
lipid homeostasisGO:005508830.012
single organism membrane fusionGO:004480120.012
positive regulation of cellular biosynthetic processGO:0031328680.012
regulation of gtp catabolic processGO:003312420.012
cellular lipid catabolic processGO:004424230.012
negative regulation of reproductive processGO:200024230.012
peptide transportGO:001583310.012
regulation of glial cell differentiationGO:004568540.012
single organism nuclear importGO:190259330.012
nitric oxide biosynthetic processGO:000680920.012
fertilizationGO:000956630.012
zymogen activationGO:003163830.012
cofactor biosynthetic processGO:0051188100.012
regulation of cytoplasmic transportGO:190364940.012
response to vitaminGO:003327330.012
embryonic organ developmentGO:00485683810.012
neurological system processGO:0050877620.012
endocardium morphogenesisGO:000316040.012
positive regulation of protein complex assemblyGO:003133420.012
cellular response to extracellular stimulusGO:003166820.012
positive regulation of gliogenesisGO:001401520.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
response to alkaloidGO:004327920.012
inner ear developmentGO:00488391260.012
regulation of transmembrane transporter activityGO:002289820.012
porphyrin containing compound biosynthetic processGO:000677980.012
negative regulation of small gtpase mediated signal transductionGO:005105810.012
positive regulation of protein polymerizationGO:003227320.011
regulation of dna templated transcription elongationGO:003278430.011
kidney developmentGO:0001822920.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
cell agingGO:000756920.011
positive regulation of gtpase activityGO:004354710.011
membrane invaginationGO:001032410.011
cytokinesisGO:000091030.011
cortical cytoskeleton organizationGO:003086510.011
protein acylationGO:004354330.011
regulation of circadian sleep wake cycleGO:004274910.011
regulation of skeletal muscle fiber developmentGO:004874220.011
regulation of protein ubiquitinationGO:003139630.011
positive regulation of secretion by cellGO:190353210.011
fatty acid transportGO:001590810.011
response to nutrientGO:000758430.011
regulation of cellular component organizationGO:0051128860.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
development of primary female sexual characteristicsGO:004654540.011
regulation of intracellular protein transportGO:003315730.011
dna templated transcription elongationGO:000635430.011
female gonad developmentGO:000858540.011
regulation of cell matrix adhesionGO:000195210.011
positive regulation of lipid metabolic processGO:004583410.011
cellular response to decreased oxygen levelsGO:003629410.011
regulation of protein localization to nucleusGO:190018020.011
gland developmentGO:00487321430.011
nephron epithelium morphogenesisGO:007208810.011
generation of neuronsGO:00486993850.011
cardiac chamber developmentGO:0003205190.011
renal system developmentGO:0072001940.011
positive regulation of cellular carbohydrate metabolic processGO:001067610.011
epithelial tube morphogenesisGO:00605621480.011
response to monosaccharideGO:003428430.011
nucleocytoplasmic transportGO:000691340.011
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.011
multi organism processGO:00517041340.011
regulation of inflammatory responseGO:005072720.011
regulation of endothelial cell differentiationGO:004560130.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
negative regulation of chromatin modificationGO:190330910.011
establishment of mitotic spindle localizationGO:0040001120.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
internal peptidyl lysine acetylationGO:001839320.011
chordate embryonic developmentGO:00430092710.011
regulation of cellular protein catabolic processGO:190336210.011
protein complex localizationGO:003150310.011
negative regulation of transcription dna templatedGO:0045892450.011
response to glucoseGO:000974930.011
digestive tract mesoderm developmentGO:000750210.010
tetrapyrrole biosynthetic processGO:003301480.010
phagocytosis engulfmentGO:000691110.010
transportGO:00068102200.010
single organism transportGO:00447652060.010
cellular response to hypoxiaGO:007145610.010
response to hexoseGO:000974630.010
protein stabilizationGO:005082120.010
cell projection assemblyGO:0030031640.010
regulation of cell cycleGO:0051726520.010
positive regulation of epithelial cell proliferationGO:005067910.010
odontogenesis of dentin containing toothGO:004247510.010
germ line stem cell maintenanceGO:003071820.010
positive regulation of transcription dna templatedGO:0045893570.010
muscle cell differentiationGO:00426921390.010
negative regulation of mapk cascadeGO:004340940.010
olfactory lobe developmentGO:002198840.010
mitotic cell cycle processGO:1903047480.010
axon midline choice point recognitionGO:001619940.010
regulation of protein import into nucleusGO:004230620.010
multicellular organismal reproductive processGO:0048609350.010
mesenchymal cell proliferationGO:001046310.010
wound healingGO:0042060900.010
tetrapyrrole metabolic processGO:0033013100.010
response to foodGO:003209410.010
spinal cord developmentGO:0021510460.010
meiotic cell cycle processGO:190304630.010
b cell activationGO:004211320.010
negative regulation of oocyte developmentGO:006028320.010
cell proliferation involved in heart morphogenesisGO:006132320.010
actin filament polymerizationGO:003004120.010
regulation of mrna processingGO:005068430.010
positive regulation of glial cell differentiationGO:004568710.010
negative regulation of biosynthetic processGO:0009890550.010
cellular component biogenesisGO:00440851780.010
interspecies interaction between organismsGO:004441940.010

hibadha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.021
disease of metabolismDOID:001466700.021
disease of anatomical entityDOID:700.020
musculoskeletal system diseaseDOID:1700.017
nervous system diseaseDOID:86300.014
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012
cardiovascular system diseaseDOID:128700.011
myopathyDOID:42300.011
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011