Danio rerio

37 known processes

zic2b

zic family member 2 (odd-paired homolog, Drosophila) b

(Aliases: hm:zeh0655,zic2l,zic2.2,MGC110428,id:ibd5017)

zic2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
aromatic compound biosynthetic processGO:00194382170.913
Zebrafish Worm Fly
organic cyclic compound biosynthetic processGO:19013622230.865
Zebrafish Worm Fly
diencephalon developmentGO:0021536580.834
Zebrafish
cellular biosynthetic processGO:00442492860.807
Zebrafish Worm Fly
embryonic organ morphogenesisGO:00485622740.781
regulation of transcription dna templatedGO:00063552130.747
Zebrafish Fly
heterocycle biosynthetic processGO:00181302150.735
Zebrafish Worm Fly
biosynthetic processGO:00090582940.674
Zebrafish Worm Fly
regulation of biosynthetic processGO:00098892500.658
Zebrafish Fly
regulation of nucleic acid templated transcriptionGO:19035062130.653
Zebrafish Fly
rna biosynthetic processGO:00327741810.648
Zebrafish Worm Fly
embryonic organ developmentGO:00485683810.643
tube morphogenesisGO:00352393490.622
Zebrafish
regulation of metabolic processGO:00192223590.602
Zebrafish Fly
regulation of nitrogen compound metabolic processGO:00511712510.586
Zebrafish Fly
cellular nitrogen compound biosynthetic processGO:00442712180.583
Zebrafish Worm Fly
cellular aromatic compound metabolic processGO:00067252950.566
Zebrafish Worm Fly
heterocycle metabolic processGO:00464832900.552
Zebrafish Worm Fly
regulation of macromolecule biosynthetic processGO:00105562250.547
Zebrafish Fly
regulation of nucleobase containing compound metabolic processGO:00192192500.542
Zebrafish Fly
neural tube developmentGO:0021915620.527
Zebrafish
organic cyclic compound metabolic processGO:19013603010.526
Zebrafish Worm Fly
negative regulation of cellular biosynthetic processGO:0031327550.513
Zebrafish
chordate embryonic developmentGO:00430092710.452
dna templated transcription initiationGO:000635210.446
Worm
morphogenesis of an epitheliumGO:00020093330.440
Zebrafish
transcription dna templatedGO:00063511810.413
Zebrafish Worm Fly
nucleobase containing compound biosynthetic processGO:00346542050.412
Zebrafish Worm Fly
generation of neuronsGO:00486993850.393
Worm
regulation of signal transductionGO:00099662250.391
Zebrafish
cell proliferation in forebrainGO:002184630.381
Zebrafish
cellular nitrogen compound metabolic processGO:00346412900.377
Zebrafish Worm Fly
negative regulation of biosynthetic processGO:0009890550.368
Zebrafish
mesenchyme developmentGO:00604851270.356
determination of left right symmetryGO:00073681790.349
Zebrafish
transcription from rna polymerase ii promoterGO:0006366800.339
Fly
neural tube formationGO:0001841160.324
Zebrafish
regulation of transcription from rna polymerase ii promoterGO:00063571140.308
Fly
epithelial tube formationGO:0072175190.305
Zebrafish
neural crest cell developmentGO:0014032620.292
developmental pigmentationGO:0048066480.288
negative regulation of nucleobase containing compound metabolic processGO:0045934590.286
Zebrafish
wnt signaling pathwayGO:0016055800.273
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.271
Zebrafish Fly
mesenchymal cell differentiationGO:0048762870.268
macromolecule biosynthetic processGO:00090592270.268
Zebrafish Worm Fly
forebrain neuron fate commitmentGO:002187710.266
negative regulation of biological processGO:00485193040.260
Zebrafish
primary neural tube formationGO:001402010.260
organic substance biosynthetic processGO:19015762890.250
Zebrafish Worm Fly
mesenchymal cell developmentGO:0014031780.249
specification of symmetryGO:00097992040.235
Zebrafish
cell migration involved in heart developmentGO:0060973220.232
negative regulation of rna metabolic processGO:0051253480.223
Zebrafish
positive regulation of nitrogen compound metabolic processGO:0051173690.222
Fly
cellular macromolecule metabolic processGO:00442603910.210
Zebrafish Worm Fly
cell surface receptor signaling pathwayGO:00071663250.205
Zebrafish Fly
nucleobase containing compound metabolic processGO:00061392740.201
Zebrafish Worm Fly
neuron developmentGO:00486662620.197
signal transductionGO:00071654550.187
Zebrafish Fly
gene expressionGO:00104672520.181
Zebrafish Worm Fly
regulation of signalingGO:00230512350.179
Zebrafish
head developmentGO:00603223030.174
Zebrafish
larval developmentGO:000216420.170
Worm
cell morphogenesisGO:00009022890.170
regionalizationGO:00030022740.165
Zebrafish
pigment cell differentiationGO:0050931380.157
epithelial tube morphogenesisGO:00605621480.154
Zebrafish
gastrulation with mouth forming secondGO:0001702440.149
neuron projection morphogenesisGO:00488121610.149
regulation of cell communicationGO:00106462320.142
Zebrafish
nucleic acid templated transcriptionGO:00976591810.142
Zebrafish Worm Fly
cell morphogenesis involved in differentiationGO:00009041950.141
developmental growthGO:00485891660.140
cell fate specificationGO:0001708680.138
Worm
axonogenesisGO:00074091520.136
regulation of rna biosynthetic processGO:20011412130.136
Zebrafish Fly
maintenance of locationGO:005123540.130
Worm
bleb assemblyGO:003206010.127
cell part morphogenesisGO:00329902460.123
regulation of primary metabolic processGO:00800903110.122
Zebrafish Fly
regulation of developmental processGO:00507932470.120
positive regulation of cellular processGO:00485222010.119
Fly
neuron projection developmentGO:00311751800.119
axon developmentGO:00615641660.118
regulation of cellular metabolic processGO:00313233200.113
Zebrafish Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.113
Zebrafish Fly
tube closureGO:006060610.113
axon guidanceGO:0007411860.113
otic vesicle developmentGO:0071599420.111
stem cell differentiationGO:00488631170.105
compound eye developmentGO:004874920.104
skeletal system morphogenesisGO:00487051020.103
neuron projection guidanceGO:0097485860.102
tube formationGO:0035148250.099
Zebrafish
negative regulation of nucleic acid templated transcriptionGO:1903507450.096
Zebrafish
negative regulation of gene expressionGO:0010629650.096
Zebrafish
digestive system developmentGO:00551232890.095
Fly
cellular macromolecule biosynthetic processGO:00346452240.095
Zebrafish Worm Fly
positive regulation of nucleobase containing compound metabolic processGO:0045935690.095
Fly
stem cell developmentGO:0048864820.094
dorsal ventral pattern formationGO:00099531250.093
Zebrafish
rna metabolic processGO:00160702190.093
Zebrafish Worm Fly
cellular component movementGO:00069283350.092
Fly
negative regulation of transcription dna templatedGO:0045892450.091
Zebrafish
cell proliferation in midbrainGO:003327840.091
Zebrafish
nitrogen compound metabolic processGO:00068073190.089
Zebrafish Worm Fly
positive regulation of macromolecule metabolic processGO:0010604930.089
Fly
forebrain developmentGO:0030900960.088
Zebrafish
regulation of rna metabolic processGO:00512522240.088
Zebrafish Fly
regulation of synapse assemblyGO:005196330.086
nucleic acid metabolic processGO:00903042440.083
Zebrafish Worm Fly
ear morphogenesisGO:0042471640.080
cell migration to the midline involved in heart developmentGO:0003318120.080
regulation of nervous system developmentGO:0051960900.080
determination of heart left right asymmetryGO:00613711170.079
determination of bilateral symmetryGO:00098552040.079
Zebrafish
neuron fate commitmentGO:0048663260.075
Worm
embryonic heart tube developmentGO:00350501330.075
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.074
Zebrafish
negative regulation of metabolic processGO:0009892860.074
Zebrafish
lipid storageGO:001991510.073
Worm
endoderm formationGO:0001706290.072
cell projection organizationGO:00300302840.072
convergent extensionGO:00600261180.070
digestive tract developmentGO:00485652650.068
Fly
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.068
embryonic epithelial tube formationGO:0001838170.065
Zebrafish
neural crest cell differentiationGO:0014033720.065
positive regulation of rna metabolic processGO:0051254590.065
Fly
brain developmentGO:00074202930.063
Zebrafish
embryonic skeletal system developmentGO:0048706970.063
cell projection morphogenesisGO:00488582440.062
growthGO:00400071740.061
determination of pancreatic left right asymmetryGO:0035469110.060
negative regulation of nitrogen compound metabolic processGO:0051172590.059
Zebrafish
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.059
locomotionGO:00400113130.058
Worm Fly
pigmentationGO:0043473850.056
negative regulation of cellular processGO:00485232830.056
Zebrafish
regulation of macromolecule metabolic processGO:00602553170.054
Zebrafish Fly
regulation of protein complex assemblyGO:004325430.052
stem cell maintenanceGO:001982740.051
synaptic growth at neuromuscular junctionGO:005112420.051
pancreatic d cell developmentGO:000332410.051
pituitary gland developmentGO:0021983160.050
regulation of bindingGO:005109830.050
urogenital system developmentGO:0001655970.049
regulation of stem cell differentiationGO:200073640.049
negative regulation of macromolecule biosynthetic processGO:0010558480.048
Zebrafish
positive regulation of catabolic processGO:000989640.048
stem cell proliferationGO:007208940.047
ectodermal placode formationGO:0060788260.047
negative regulation of rna biosynthetic processGO:1902679450.046
Zebrafish
regulation of neural precursor cell proliferationGO:200017730.045
endodermal cell fate determinationGO:000749320.044
regulation of cell differentiationGO:00455951420.044
ectodermal placode morphogenesisGO:0071697320.044
negative regulation of signalingGO:0023057960.044
glial cell fate determinationGO:000740310.043
neural crest formationGO:0014029140.042
enzyme linked receptor protein signaling pathwayGO:00071671060.042
Fly
positive regulation of metabolic processGO:00098931080.040
Fly
neuron differentiationGO:00301823530.040
Worm
embryo development ending in birth or egg hatchingGO:00097922710.040
negative regulation of cellular metabolic processGO:0031324770.040
Zebrafish
central nervous system developmentGO:00074173870.040
Zebrafish
heart morphogenesisGO:00030071560.039
regulation of gene expressionGO:00104682650.039
Zebrafish Fly
forebrain anterior posterior pattern specificationGO:002179730.039
regulation of response to stimulusGO:00485832690.039
Zebrafish
negative regulation of ras protein signal transductionGO:004658010.038
negative regulation of small gtpase mediated signal transductionGO:005105810.038
cardioblast migration to the midline involved in heart field formationGO:006097570.038
regulation of endodermal cell differentiationGO:1903224150.038
abducens nucleus developmentGO:002174220.037
negative regulation of purine nucleotide metabolic processGO:190054370.037
positive regulation of nucleic acid templated transcriptionGO:1903508570.037
Fly
positive regulation of biological processGO:00485182530.036
Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.036
neuron fate specificationGO:0048665200.036
Worm
regulation of neuron differentiationGO:0045664560.036
regulation of cell fate specificationGO:0042659200.035
germ line stem cell maintenanceGO:003071820.035
phosphorus metabolic processGO:00067931090.034
gastrulationGO:00073692080.034
cellular component morphogenesisGO:00329893360.034
ventral spinal cord interneuron differentiationGO:0021514120.034
odontogenesis of dentin containing toothGO:004247510.034
neural precursor cell proliferationGO:0061351200.033
Zebrafish
anterior posterior pattern specificationGO:00099521520.033
Zebrafish
protein localization to nucleusGO:003450430.033
regulation of synapse organizationGO:005080730.032
taxisGO:00423301090.032
regulation of wnt signaling pathwayGO:0030111530.032
tissue regenerationGO:0042246740.032
positive regulation of cellular biosynthetic processGO:0031328680.031
Fly
sensory organ morphogenesisGO:00905962000.031
Zebrafish
lateral line ganglion developmentGO:004889020.030
protein acylationGO:004354330.030
covalent chromatin modificationGO:0016569200.030
carbohydrate derivative biosynthetic processGO:1901137430.030
sympathetic nervous system developmentGO:004848530.029
epibolyGO:0090504410.029
regulation of chondrocyte differentiationGO:003233010.029
protein acetylationGO:000647320.029
melanocyte differentiationGO:0030318260.028
regulation of multicellular organismal developmentGO:20000262230.028
cranial ganglion developmentGO:006155030.028
gabaergic neuron differentiationGO:009715420.027
astrocyte differentiationGO:004870810.027
ectodermal placode developmentGO:0071696370.026
protein polymerizationGO:005125840.026
positive regulation of jun kinase activityGO:004350720.026
epithelial cell morphogenesisGO:000338220.026
neuroblast differentiationGO:001401610.026
regulation of smoothened signaling pathwayGO:0008589180.026
Zebrafish
anatomical structure arrangementGO:004853220.025
spinal cord motor neuron differentiationGO:0021522260.024
blood vessel developmentGO:00015682460.024
phosphate containing compound metabolic processGO:00067961080.024
epithelial structure maintenanceGO:001066980.024
olfactory placode formationGO:003091010.024
epiboly involved in gastrulation with mouth forming secondGO:0055113350.024
single organism organelle organizationGO:19025891990.023
hatching gland developmentGO:004878530.023
positive regulation of macromolecule biosynthetic processGO:0010557590.023
Fly
internal protein amino acid acetylationGO:000647520.023
embryonic limb morphogenesisGO:003032620.023
regulation of neurogenesisGO:0050767870.023
positive regulation of transportGO:005105020.023
neural crest cell migrationGO:0001755420.022
hepaticobiliary system developmentGO:0061008980.022
retina development in camera type eyeGO:00600411460.022
Zebrafish
bone mineralizationGO:003028290.022
mesoderm morphogenesisGO:0048332510.022
columnar cuboidal epithelial cell differentiationGO:0002065380.022
cardioblast migrationGO:000326070.022
fin developmentGO:0033333770.022
chromatin modificationGO:0016568210.021
cell differentiation in spinal cordGO:0021515400.021
cell proliferation in hindbrainGO:002153440.021
Zebrafish
single organism metabolic processGO:00447102170.021
immunoglobulin mediated immune responseGO:001606430.021
regulation of inner ear receptor cell differentiationGO:200098010.021
negative regulation of histone modificationGO:003105710.021
regulation of cell developmentGO:00602841000.021
regulation of embryonic developmentGO:0045995470.021
establishment of localizationGO:00512342440.021
regulation of chromosome segregationGO:005198310.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
connective tissue developmentGO:0061448990.020
blood vessel morphogenesisGO:00485142160.020
actin filament based processGO:0030029640.020
mesodermal cell fate specificationGO:0007501120.020
regulation of gastrulationGO:0010470240.020
camera type eye developmentGO:00430102220.020
Zebrafish
neuroblast proliferationGO:000740520.020
forebrain morphogenesisGO:004885360.020
Zebrafish
heart loopingGO:0001947940.020
heparan sulfate proteoglycan biosynthetic processGO:001501250.020
positive regulation of rna biosynthetic processGO:1902680570.020
Fly
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.020
Fly
endocardial progenitor cell migration to the midline involved in heart field formationGO:000326240.019
cell migrationGO:00164772370.019
Fly
regulation of cytoplasmic transportGO:190364940.019
negative regulation of cell communicationGO:0010648960.019
sensory organ developmentGO:00074233930.019
Zebrafish
regulation of neuron projection developmentGO:0010975400.019
spinal cord developmentGO:0021510460.018
Zebrafish
nerve developmentGO:0021675450.018
guanosine containing compound metabolic processGO:190106840.018
single organism nuclear importGO:190259330.018
skin developmentGO:0043588540.018
negative regulation of striated muscle tissue developmentGO:004584320.018
cartilage developmentGO:0051216960.018
positive regulation of stem cell proliferationGO:200064810.018
regulation of jun kinase activityGO:004350630.017
morphogenesis of an epithelial sheetGO:0002011490.017
epidermis developmentGO:0008544480.017
regulation of canonical wnt signaling pathwayGO:0060828340.017
regulation of epithelial to mesenchymal transitionGO:001071730.017
optic nerve formationGO:002163460.017
chemotaxisGO:00069351040.016
small molecule metabolic processGO:0044281770.016
protein metabolic processGO:00195381830.016
fin regenerationGO:0031101510.016
single organism reproductive processGO:0044702400.016
Worm Fly
forebrain regionalizationGO:002187140.016
embryonic hemopoiesisGO:0035162530.016
respiratory system developmentGO:006054150.016
endothelial cell differentiationGO:0045446200.016
multicellular organism growthGO:003526440.016
neuroepithelial cell differentiationGO:0060563260.016
skeletal system developmentGO:00015011810.016
establishment of protein localization to organelleGO:007259440.015
regulation of multicellular organism growthGO:004001440.015
positive regulation of cellular component biogenesisGO:004408930.015
iridophore differentiationGO:005093590.015
megakaryocyte differentiationGO:003021910.015
eye developmentGO:00016542770.015
Zebrafish
macromolecule localizationGO:0033036540.015
Worm
regulation of cellular protein metabolic processGO:0032268520.015
regulation of dendrite developmentGO:005077330.015
cellular response to retinoic acidGO:007130010.015
regulation of muscle organ developmentGO:004863490.015
localization of cellGO:00516742440.015
Fly
protein complex biogenesisGO:0070271300.015
nuclear transportGO:005116940.015
multicellular organism reproductionGO:0032504350.015
Worm Fly
regulation of rho protein signal transductionGO:003502320.014
regulation of multicellular organismal processGO:00512392770.014
hindbrain developmentGO:0030902910.014
Zebrafish
gliogenesisGO:0042063450.014
single organism biosynthetic processGO:0044711710.014
nephron morphogenesisGO:007202820.014
ventral spinal cord interneuron specificationGO:002152130.014
multi organism processGO:00517041340.014
Worm Fly
regulation of gene expression epigeneticGO:0040029110.014
positive regulation of gtp catabolic processGO:003312610.014
protein targeting to nucleusGO:004474430.014
positive regulation of cellular metabolic processGO:0031325940.014
Fly
regulation of establishment of protein localizationGO:007020140.014
determination of left right asymmetry in nervous systemGO:003554540.014
deathGO:00162651210.014
macromolecule modificationGO:00434121110.013
heart developmentGO:00075073130.013
male meiosisGO:000714020.013
developmental process involved in reproductionGO:0003006270.013
Worm
otic vesicle morphogenesisGO:0071600340.013
regulation of apoptotic processGO:0042981980.013
regulation of nucleocytoplasmic transportGO:004682220.013
protein importGO:001703830.013
small gtpase mediated signal transductionGO:000726480.013
inner ear developmentGO:00488391260.013
negative regulation of chromosome organizationGO:200125110.013
cell migration involved in heart formationGO:0060974100.013
liver developmentGO:0001889960.013
glial cell fate commitmentGO:002178160.013
gtp catabolic processGO:000618420.013
regulation of translational initiationGO:000644610.012
regulation of protein import into nucleusGO:004230620.012
pronephros developmentGO:0048793690.012
cellular protein metabolic processGO:00442671290.012
sex determinationGO:000753010.012
cranial nerve developmentGO:0021545420.012
neural plate regionalizationGO:0060897100.012
convergent extension involved in organogenesisGO:0060029100.012
regulation of stem cell proliferationGO:007209120.012
regulation of protein transportGO:005122330.012
notochord developmentGO:0030903540.012
autonomic nervous system developmentGO:0048483190.012
regulation of establishment of planar polarityGO:009017540.012
dendrite morphogenesisGO:004881350.012
mesoderm developmentGO:0007498880.012
striated muscle cell developmentGO:00550021080.012
determination of left right asymmetry in diencephalonGO:003546240.012
regulation of cellular component biogenesisGO:0044087120.012
wound healingGO:0042060900.012
establishment of localization in cellGO:0051649770.012
positive regulation of multi organism processGO:004390230.012
translational initiationGO:000641330.012
negative regulation of programmed cell deathGO:0043069580.012
single organism transportGO:00447652060.012
pancreas developmentGO:0031016840.012
camera type eye morphogenesisGO:00485931080.012
Zebrafish
positive regulation of reproductive processGO:200024320.012
germ cell migrationGO:000835480.012
Fly
regulation of cellular component organizationGO:0051128860.012
regulation of catenin import into nucleusGO:003541220.011
embryonic cranial skeleton morphogenesisGO:0048701900.011
negative regulation of macromolecule metabolic processGO:0010605760.011
Zebrafish
regulation of protein localization to nucleusGO:190018020.011
immunoglobulin productionGO:000237710.011
neural plate anterior posterior regionalizationGO:002199980.011
organelle organizationGO:00069962270.011
negative regulation of synapse assemblyGO:005196420.011
midbrain developmentGO:0030901280.011
Zebrafish
central nervous system myelinationGO:002201020.011
rho protein signal transductionGO:000726650.011
epithelial cell developmentGO:0002064420.011
morphogenesis of embryonic epitheliumGO:0016331300.011
Zebrafish
patterning of blood vesselsGO:0001569150.011
canonical wnt signaling pathwayGO:0060070480.011
Zebrafish
response to external biotic stimulusGO:0043207970.011
ventral spinal cord developmentGO:0021517350.011
ameboidal type cell migrationGO:00016671430.011
regulation of cell deathGO:00109411030.010
regulation of nucleoside metabolic processGO:000911820.010
regulation of extent of cell growthGO:0061387290.010
adult behaviorGO:003053420.010
carbohydrate derivative metabolic processGO:1901135610.010
cellular localizationGO:0051641970.010
optic placode formationGO:000174340.010
multi organism reproductive processGO:0044703360.010
Worm Fly
regulation of protein targetingGO:190353320.010
response to stressGO:00069502630.010
wnt signaling pathway involved in somitogenesisGO:009024420.010
neuron projection extensionGO:1990138450.010

zic2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:008001500.070
congenital nervous system abnormalityDOID:249000.070
gastrointestinal system cancerDOID:311900.026
colorectal cancerDOID:925600.026
cancerDOID:16200.026
disease of cellular proliferationDOID:1456600.026
intestinal cancerDOID:1015500.026
organ system cancerDOID:005068600.026
large intestine cancerDOID:567200.026
disease of anatomical entityDOID:700.013