IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

chrna6

cholinergic receptor, nicotinic, alpha 6

(Aliases: si:dkey-234d14.1)

ZFIN: ZDB-GENE-090312-91
Entrez: 555747
Ensembl: ENSDARG00000055559
UniProtKB: Q0PJT9

Process Predictions
Disease Predictions

chrna6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of cellular biosynthetic process	GO:0031326	245	0.898
rna biosynthetic process	GO:0032774	181	0.845
organic substance biosynthetic process	GO:1901576	289	0.773
nucleobase containing compound metabolic process	GO:0006139	274	0.767
regulation of rna biosynthetic process	GO:2001141	213	0.761
chemotaxis	GO:0006935	104	0.743	Zebrafish
heterocycle metabolic process	GO:0046483	290	0.730
nucleic acid templated transcription	GO:0097659	181	0.682
gene expression	GO:0010467	252	0.680
regulation of biosynthetic process	GO:0009889	250	0.680
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.641
neuron projection development	GO:0031175	180	0.625	Zebrafish
central nervous system development	GO:0007417	387	0.623
nucleobase containing compound biosynthetic process	GO:0034654	205	0.618
biosynthetic process	GO:0009058	294	0.613
organic cyclic compound biosynthetic process	GO:1901362	223	0.568
axonogenesis	GO:0007409	152	0.557	Zebrafish
regulation of gene expression	GO:0010468	265	0.548
generation of neurons	GO:0048699	385	0.545	Zebrafish
auditory receptor cell fate commitment	GO:0009912	4	0.527
dopamine metabolic process	GO:0042417	2	0.511
regulation of nucleic acid templated transcription	GO:1903506	213	0.506
heterocycle biosynthetic process	GO:0018130	215	0.503
neuron differentiation	GO:0030182	353	0.502	Zebrafish
macromolecule biosynthetic process	GO:0009059	227	0.501
taxis	GO:0042330	109	0.499	Zebrafish
rna metabolic process	GO:0016070	219	0.495
regulation of rna metabolic process	GO:0051252	224	0.494
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.493
regulation of transcription dna templated	GO:0006355	213	0.491
cellular macromolecule biosynthetic process	GO:0034645	224	0.490
axon development	GO:0061564	166	0.476	Zebrafish
aromatic compound biosynthetic process	GO:0019438	217	0.473
nucleic acid metabolic process	GO:0090304	244	0.459
cell part morphogenesis	GO:0032990	246	0.447	Zebrafish
cellular macromolecule metabolic process	GO:0044260	391	0.443
sensory organ development	GO:0007423	393	0.442
cell projection morphogenesis	GO:0048858	244	0.437	Zebrafish
transcription dna templated	GO:0006351	181	0.435
regulation of nitrogen compound metabolic process	GO:0051171	251	0.408
head development	GO:0060322	303	0.390
regulation of macromolecule biosynthetic process	GO:0010556	225	0.380
central nervous system neuron differentiation	GO:0021953	74	0.376
monoamine transport	GO:0015844	1	0.370	Mouse
cellular component movement	GO:0006928	335	0.369	Zebrafish
regulation of cellular metabolic process	GO:0031323	320	0.367
neuron projection guidance	GO:0097485	86	0.356	Zebrafish
cellular biosynthetic process	GO:0044249	286	0.356
cellular nitrogen compound metabolic process	GO:0034641	290	0.346
axon guidance	GO:0007411	86	0.331	Zebrafish
brain development	GO:0007420	293	0.330
adult behavior	GO:0030534	2	0.327
eye development	GO:0001654	277	0.305
regulation of primary metabolic process	GO:0080090	311	0.305
regulation of macromolecule metabolic process	GO:0060255	317	0.302
response to external stimulus	GO:0009605	264	0.300	Zebrafish
cation transmembrane transport	GO:0098655	65	0.295	Zebrafish Mouse
response to chemical	GO:0042221	320	0.292	Zebrafish
neuron migration	GO:0001764	22	0.282
gabaergic neuron differentiation	GO:0097154	2	0.281
response to organic substance	GO:0010033	153	0.268
catecholamine metabolic process	GO:0006584	2	0.265
skeletal muscle tissue development	GO:0007519	67	0.246	Zebrafish
establishment of localization	GO:0051234	244	0.237	Zebrafish Mouse Worm
negative regulation of biological process	GO:0048519	304	0.235
multicellular organismal response to stress	GO:0033555	2	0.231
regulation of metabolic process	GO:0019222	359	0.230
system process	GO:0003008	185	0.228
regeneration	GO:0031099	91	0.227
embryonic organ morphogenesis	GO:0048562	274	0.225
muscle organ development	GO:0007517	101	0.214	Zebrafish
cell projection organization	GO:0030030	284	0.209	Zebrafish
signal transduction	GO:0007165	455	0.208	Zebrafish Worm
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.201
sprouting angiogenesis	GO:0002040	53	0.201
blood vessel morphogenesis	GO:0048514	216	0.200
nitrogen compound metabolic process	GO:0006807	319	0.198
regulation of axon extension	GO:0030516	24	0.193	Zebrafish
regulation of multicellular organismal process	GO:0051239	277	0.192	Zebrafish Worm
forebrain neuron development	GO:0021884	7	0.191
cell morphogenesis	GO:0000902	289	0.184	Zebrafish
spinal cord motor neuron differentiation	GO:0021522	26	0.182
regulation of circadian rhythm	GO:0042752	4	0.182
chordate embryonic development	GO:0043009	271	0.176
camera type eye morphogenesis	GO:0048593	108	0.174
positive regulation of biological process	GO:0048518	253	0.167
angiogenesis	GO:0001525	158	0.154
transmembrane transport	GO:0055085	120	0.154	Zebrafish Mouse Worm
negative regulation of cellular process	GO:0048523	283	0.152
camera type eye development	GO:0043010	222	0.149
regulation of extrinsic apoptotic signaling pathway	GO:2001236	3	0.149
locomotion	GO:0040011	313	0.145	Zebrafish Worm
ion transmembrane transport	GO:0034220	91	0.144	Zebrafish Mouse Worm
positive regulation of metabolic process	GO:0009893	108	0.143
central nervous system neuron axonogenesis	GO:0021955	18	0.141
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.140
response to stress	GO:0006950	263	0.138
cellular amine metabolic process	GO:0044106	2	0.138
embryo development ending in birth or egg hatching	GO:0009792	271	0.135
cell migration	GO:0016477	237	0.134	Zebrafish
digestive system development	GO:0055123	289	0.133
muscle structure development	GO:0061061	196	0.132	Zebrafish
ameboidal type cell migration	GO:0001667	143	0.129
ion transport	GO:0006811	114	0.124	Zebrafish Mouse Worm
organic cyclic compound metabolic process	GO:1901360	301	0.123
cell motility	GO:0048870	244	0.121	Zebrafish
cell differentiation in spinal cord	GO:0021515	40	0.120
positive regulation of transcription dna templated	GO:0045893	57	0.118
transcription from rna polymerase ii promoter	GO:0006366	80	0.117
forebrain development	GO:0030900	96	0.116
cellular aromatic compound metabolic process	GO:0006725	295	0.115
sensory organ morphogenesis	GO:0090596	200	0.113
cell surface receptor signaling pathway	GO:0007166	325	0.111
neuromuscular process controlling balance	GO:0050885	3	0.111
neurological system process	GO:0050877	62	0.110
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.109	Zebrafish
skeletal system development	GO:0001501	181	0.109	Zebrafish
positive regulation of gene expression	GO:0010628	71	0.109
morphogenesis of an epithelium	GO:0002009	333	0.109	Zebrafish
astrocyte differentiation	GO:0048708	1	0.109
spinal cord development	GO:0021510	46	0.109
skin development	GO:0043588	54	0.109
embryonic organ development	GO:0048568	381	0.107
behavior	GO:0007610	74	0.104	Worm
photoreceptor cell differentiation	GO:0046530	55	0.104
circulatory system process	GO:0003013	87	0.104
tube morphogenesis	GO:0035239	349	0.103
enzyme linked receptor protein signaling pathway	GO:0007167	106	0.101
neuron development	GO:0048666	262	0.099	Zebrafish
olfactory lobe development	GO:0021988	4	0.098
inner ear receptor cell fate commitment	GO:0060120	4	0.098
response to endogenous stimulus	GO:0009719	83	0.098
metal ion homeostasis	GO:0055065	26	0.098
neuron projection morphogenesis	GO:0048812	161	0.096	Zebrafish
swimming behavior	GO:0036269	8	0.095
cell morphogenesis involved in differentiation	GO:0000904	195	0.093	Zebrafish
cation transport	GO:0006812	81	0.092	Zebrafish Mouse
sympathetic nervous system development	GO:0048485	3	0.092
cell cycle	GO:0007049	93	0.091
positive regulation of macromolecule biosynthetic process	GO:0010557	59	0.089
positive regulation of cellular biosynthetic process	GO:0031328	68	0.087
amine metabolic process	GO:0009308	2	0.087
erythrocyte differentiation	GO:0030218	54	0.085
regulation of reproductive process	GO:2000241	4	0.085	Worm
myeloid cell development	GO:0061515	32	0.084
phagocytosis	GO:0006909	3	0.084
larval development	GO:0002164	2	0.084
striated muscle tissue development	GO:0014706	110	0.084	Zebrafish
cellular response to chemical stimulus	GO:0070887	157	0.083
central nervous system neuron development	GO:0021954	29	0.082
retina development in camera type eye	GO:0060041	146	0.082
mesoderm morphogenesis	GO:0048332	51	0.082
midbrain development	GO:0030901	28	0.081
alpha amino acid metabolic process	GO:1901605	3	0.080
epidermis development	GO:0008544	48	0.079
single organism transport	GO:0044765	206	0.079	Zebrafish Mouse Worm
synaptic transmission	GO:0007268	35	0.078	Zebrafish Worm
digestive tract development	GO:0048565	265	0.077
posterior lateral line neuromast hair cell differentiation	GO:0048923	8	0.075
peripheral nervous system neuron differentiation	GO:0048934	28	0.074
catechol containing compound biosynthetic process	GO:0009713	2	0.074
myeloid cell differentiation	GO:0030099	86	0.074
multicellular organism reproduction	GO:0032504	35	0.073	Worm
positive regulation of cell development	GO:0010720	25	0.073
tissue migration	GO:0090130	37	0.073
regionalization	GO:0003002	274	0.072
embryonic camera type eye development	GO:0031076	29	0.071
retina morphogenesis in camera type eye	GO:0060042	79	0.070
reproduction	GO:0000003	40	0.070	Worm
osteoclast differentiation	GO:0030316	1	0.070
regulation of glial cell differentiation	GO:0045685	4	0.068
ear development	GO:0043583	127	0.067
positive regulation of cell adhesion	GO:0045785	1	0.066
immune system process	GO:0002376	241	0.065
positive regulation of biosynthetic process	GO:0009891	68	0.065
stem cell proliferation	GO:0072089	4	0.064
cell proliferation	GO:0008283	80	0.064
response to amine	GO:0014075	1	0.063
auditory receptor cell fate determination	GO:0042668	2	0.063
eye morphogenesis	GO:0048592	144	0.063
ventral spinal cord development	GO:0021517	35	0.063
embryonic retina morphogenesis in camera type eye	GO:0060059	22	0.062
inner ear development	GO:0048839	126	0.061
negative regulation of nucleobase containing compound metabolic process	GO:0045934	59	0.061
auditory receptor cell differentiation	GO:0042491	15	0.058
organic hydroxy compound biosynthetic process	GO:1901617	6	0.058
regulation of neurogenesis	GO:0050767	87	0.058	Zebrafish
regulation of cell cycle	GO:0051726	52	0.058
olfactory bulb development	GO:0021772	4	0.057
forebrain neuron differentiation	GO:0021879	14	0.057
telencephalon development	GO:0021537	14	0.056
positive regulation of rna metabolic process	GO:0051254	59	0.055
negative regulation of programmed cell death	GO:0043069	58	0.055
regulation of transport	GO:0051049	45	0.055	Mouse
cranial nerve development	GO:0021545	42	0.054
extrinsic apoptotic signaling pathway	GO:0097191	3	0.054
optomotor response	GO:0071632	1	0.053
auditory receptor cell development	GO:0060117	8	0.052
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	4	0.052
type b pancreatic cell development	GO:0003323	4	0.052
fin morphogenesis	GO:0033334	53	0.051
pancreatic d cell differentiation	GO:0003311	2	0.049
nuclear migration	GO:0007097	3	0.049
lateral line system development	GO:0048925	76	0.049
circadian sleep wake cycle sleep	GO:0050802	1	0.049
epithelial cell differentiation	GO:0030855	116	0.048
photoreceptor cell development	GO:0042461	40	0.048
regulation of programmed cell death	GO:0043067	101	0.048
stem cell differentiation	GO:0048863	117	0.048
localization of cell	GO:0051674	244	0.048	Zebrafish
regulation of multicellular organismal development	GO:2000026	223	0.048	Zebrafish
vasculature development	GO:0001944	278	0.047
phospholipase c activating g protein coupled receptor signaling pathway	GO:0007200	2	0.047
catechol containing compound metabolic process	GO:0009712	2	0.047
regulation of hormone secretion	GO:0046883	2	0.047
phosphorus metabolic process	GO:0006793	109	0.047
endocardium morphogenesis	GO:0003160	4	0.046
forebrain cell migration	GO:0021885	1	0.045
blood vessel development	GO:0001568	246	0.045
sensory perception	GO:0007600	39	0.045
muscle tissue development	GO:0060537	110	0.045	Zebrafish
stem cell division	GO:0017145	1	0.045
positive regulation of jak stat cascade	GO:0046427	2	0.045
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.044
hair cell differentiation	GO:0035315	32	0.044
forebrain generation of neurons	GO:0021872	14	0.044
cell substrate junction assembly	GO:0007044	2	0.043
regulation of extent of cell growth	GO:0061387	29	0.043	Zebrafish
pancreas development	GO:0031016	84	0.042
regulation of stem cell proliferation	GO:0072091	2	0.042
hemopoiesis	GO:0030097	183	0.042
artery development	GO:0060840	22	0.041
positive regulation of cellular process	GO:0048522	201	0.041
cognition	GO:0050890	1	0.041
multicellular organism growth	GO:0035264	4	0.041
locomotor rhythm	GO:0045475	3	0.040
mesenchymal cell differentiation	GO:0048762	87	0.040
exocrine pancreas development	GO:0031017	28	0.040
rhythmic process	GO:0048511	21	0.040
response to external biotic stimulus	GO:0043207	97	0.040
regulation of nervous system development	GO:0051960	90	0.039	Zebrafish
circadian rhythm	GO:0007623	19	0.039
medulla oblongata development	GO:0021550	4	0.039
epidermal cell differentiation	GO:0009913	36	0.039
negative regulation of dna replication	GO:0008156	2	0.039
regulation of axonogenesis	GO:0050770	32	0.038	Zebrafish
detection of temperature stimulus	GO:0016048	0	0.038
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	68	0.038
regulation of endothelial cell differentiation	GO:0045601	3	0.037
epithelium migration	GO:0090132	25	0.037
pancreatic a cell development	GO:0003322	2	0.037
regulation of molecular function	GO:0065009	70	0.037
cellular component morphogenesis	GO:0032989	336	0.037	Zebrafish
smooth muscle contraction	GO:0006939	2	0.036
blood circulation	GO:0008015	87	0.036
regulation of cell development	GO:0060284	100	0.036	Zebrafish
positive regulation of macromolecule metabolic process	GO:0010604	93	0.036
female gonad development	GO:0008585	4	0.036
regulation of localization	GO:0032879	104	0.036	Mouse
sensory system development	GO:0048880	76	0.036
regulation of cellular amine metabolic process	GO:0033238	0	0.036
neural retina development	GO:0003407	49	0.036
cellular response to organic substance	GO:0071310	105	0.035
positive regulation of transport	GO:0051050	2	0.035
neuroblast proliferation	GO:0007405	2	0.035
epithelial tube formation	GO:0072175	19	0.035
hindbrain development	GO:0030902	91	0.035
pectoral fin development	GO:0033339	50	0.035
regulation of cellular ketone metabolic process	GO:0010565	7	0.035
cell death	GO:0008219	121	0.035
mesoderm development	GO:0007498	88	0.035
regulation of cell activation	GO:0050865	1	0.034
response to hydrogen peroxide	GO:0042542	3	0.034
negative regulation of metabolic process	GO:0009892	86	0.034
cellular carbohydrate metabolic process	GO:0044262	4	0.034
response to amphetamine	GO:0001975	1	0.034
death	GO:0016265	121	0.034
mesoderm formation	GO:0001707	43	0.034
positive regulation of nucleic acid templated transcription	GO:1903508	57	0.034
positive regulation of nervous system development	GO:0051962	25	0.034
regulation of blood pressure	GO:0008217	1	0.034
endocardium formation	GO:0060214	1	0.034
cardiac cell fate commitment	GO:0060911	1	0.033
response to organonitrogen compound	GO:0010243	12	0.033
multicellular organismal reproductive process	GO:0048609	35	0.033	Worm
circadian sleep wake cycle	GO:0042745	2	0.033
positive regulation of neural precursor cell proliferation	GO:2000179	1	0.032
establishment of blood brain barrier	GO:0060856	2	0.032
response to decreased oxygen levels	GO:0036293	25	0.032
gland development	GO:0048732	143	0.032
axon extension	GO:0048675	45	0.032	Zebrafish
negative regulation of apoptotic process	GO:0043066	55	0.032
sensory perception of pain	GO:0019233	1	0.032
aging	GO:0007568	2	0.032
stem cell development	GO:0048864	82	0.031
protein secretion	GO:0009306	1	0.031
negative regulation of transcription dna templated	GO:0045892	45	0.031
sensory perception of chemical stimulus	GO:0007606	3	0.031
positive regulation of rna biosynthetic process	GO:1902680	57	0.031
appendage development	GO:0048736	80	0.031
development of primary female sexual characteristics	GO:0046545	4	0.031
growth	GO:0040007	174	0.031	Zebrafish
sensory neuron axon guidance	GO:0097374	3	0.031
sympathetic ganglion development	GO:0061549	2	0.031
inorganic ion transmembrane transport	GO:0098660	57	0.031
pectoral fin morphogenesis	GO:0035138	29	0.031
axis elongation involved in somitogenesis	GO:0090245	2	0.031
lymph vessel development	GO:0001945	27	0.030
negative regulation of gene expression	GO:0010629	65	0.030
regulation of cell growth	GO:0001558	29	0.030	Zebrafish
tyrosine phosphorylation of stat protein	GO:0007260	1	0.030
oligodendrocyte differentiation	GO:0048709	23	0.030
indole containing compound metabolic process	GO:0042430	2	0.030
erythrocyte homeostasis	GO:0034101	55	0.030
phenol containing compound biosynthetic process	GO:0046189	4	0.029
regulation of membrane potential	GO:0042391	23	0.029	Zebrafish Mouse
response to alkaloid	GO:0043279	2	0.029
response to wounding	GO:0009611	116	0.029
apoptotic process	GO:0006915	116	0.029
negative regulation of gliogenesis	GO:0014014	1	0.029
determination of intestine left right asymmetry	GO:0071908	2	0.029
regulation of cell size	GO:0008361	29	0.029	Zebrafish
appendage morphogenesis	GO:0035107	56	0.028
regulation of anatomical structure size	GO:0090066	33	0.028	Zebrafish
mitotic dna integrity checkpoint	GO:0044774	4	0.028
myeloid cell homeostasis	GO:0002262	56	0.028
neural crest cell development	GO:0014032	62	0.028
multi organism process	GO:0051704	134	0.028	Worm
segmentation	GO:0035282	97	0.028
response to inorganic substance	GO:0010035	38	0.028
skeletal system morphogenesis	GO:0048705	102	0.027	Zebrafish
retina layer formation	GO:0010842	24	0.027
negative regulation of macromolecule metabolic process	GO:0010605	76	0.027
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	2	0.027
gastrulation	GO:0007369	208	0.027
cell fate commitment	GO:0045165	99	0.027
cellular response to oxygen levels	GO:0071453	1	0.027
serotonin metabolic process	GO:0042428	1	0.026
phosphate containing compound metabolic process	GO:0006796	108	0.026
response to oxygen containing compound	GO:1901700	55	0.026
formation of primary germ layer	GO:0001704	62	0.026
mechanoreceptor differentiation	GO:0042490	37	0.026
positive regulation of cell cycle	GO:0045787	3	0.026
glucose homeostasis	GO:0042593	1	0.026
regulation of tyrosine phosphorylation of stat3 protein	GO:0042516	1	0.026
negative regulation of axon extension involved in axon guidance	GO:0048843	1	0.026
cellular pigmentation	GO:0033059	30	0.026
skeletal muscle organ development	GO:0060538	78	0.026	Zebrafish
pigmentation	GO:0043473	85	0.025
regulation of gene expression epigenetic	GO:0040029	11	0.025
homeostasis of number of cells	GO:0048872	62	0.025
regulation of neuron differentiation	GO:0045664	56	0.025	Zebrafish
neural crest cell migration	GO:0001755	42	0.025
response to nitrogen compound	GO:1901698	19	0.025
negative regulation of chemotaxis	GO:0050922	4	0.025
negative regulation of nitrogen compound metabolic process	GO:0051172	59	0.025
cellular component biogenesis	GO:0044085	178	0.024	Zebrafish
exocrine system development	GO:0035272	28	0.024
regulation of receptor mediated endocytosis	GO:0048259	4	0.024
oxoacid metabolic process	GO:0043436	31	0.024
nerve development	GO:0021675	45	0.024
locomotory behavior	GO:0007626	34	0.024
regulation of ion transport	GO:0043269	22	0.024	Mouse
peripheral nervous system neuron development	GO:0048935	22	0.024
innervation	GO:0060384	3	0.024
muscle cell differentiation	GO:0042692	139	0.024	Zebrafish
cellular response to decreased oxygen levels	GO:0036294	1	0.024
urogenital system development	GO:0001655	97	0.023
sodium ion transport	GO:0006814	24	0.023
neuron fate commitment	GO:0048663	26	0.023
determination of bilateral symmetry	GO:0009855	204	0.023
response to hypoxia	GO:0001666	25	0.023
dendrite guidance	GO:0070983	0	0.023
axonal defasciculation	GO:0007414	2	0.023
organonitrogen compound biosynthetic process	GO:1901566	47	0.023
positive regulation of cell differentiation	GO:0045597	30	0.023
regulation of behavior	GO:0050795	24	0.023	Worm
negative regulation of locomotion	GO:0040013	18	0.023
pronephros development	GO:0048793	69	0.023
action potential	GO:0001508	19	0.023
regulation of cell death	GO:0010941	103	0.022
protein modification process	GO:0036211	100	0.022
positive regulation of nucleobase containing compound metabolic process	GO:0045935	69	0.022
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.022
response to bacterium	GO:0009617	58	0.022
positive regulation of cellular metabolic process	GO:0031325	94	0.022
cellular response to endogenous stimulus	GO:0071495	68	0.022
polarized epithelial cell differentiation	GO:0030859	4	0.022
single organism localization	GO:1902578	225	0.022	Zebrafish Mouse Worm
cardiogenic plate morphogenesis	GO:0003142	1	0.022
cerebellar granular layer formation	GO:0021684	3	0.022
negative chemotaxis	GO:0050919	1	0.022
embryonic camera type eye formation	GO:0060900	10	0.022
eye photoreceptor cell development	GO:0042462	30	0.022
axon regeneration	GO:0031103	14	0.022
tube closure	GO:0060606	1	0.022
regulation of cytokine production	GO:0001817	3	0.021
maintenance of location	GO:0051235	4	0.021
developmental programmed cell death	GO:0010623	4	0.021
cell migration involved in gastrulation	GO:0042074	79	0.021
cerebellar granule cell differentiation	GO:0021707	3	0.021
primary amino compound metabolic process	GO:1901160	1	0.021
cellular ketone metabolic process	GO:0042180	11	0.021
carboxylic acid metabolic process	GO:0019752	22	0.021
response to growth factor	GO:0070848	39	0.021
response to nicotine	GO:0035094	2	0.021
heart process	GO:0003015	71	0.021
positive regulation of developmental process	GO:0051094	50	0.021
positive regulation of cellular amine metabolic process	GO:0033240	0	0.021
heart development	GO:0007507	313	0.021
motor neuron axon guidance	GO:0008045	23	0.021	Zebrafish
cell substrate adhesion	GO:0031589	4	0.021
epithelial tube morphogenesis	GO:0060562	148	0.021
neuron projection regeneration	GO:0031102	16	0.021
inner ear receptor stereocilium organization	GO:0060122	8	0.021
positive regulation of multicellular organismal process	GO:0051240	52	0.021
epithelial cell fate commitment	GO:0072148	11	0.021
regulation of cell differentiation	GO:0045595	142	0.020	Zebrafish
positive regulation of secretion	GO:0051047	1	0.020
regulation of apoptotic process	GO:0042981	98	0.020
regulation of meiotic cell cycle	GO:0051445	1	0.020
determination of digestive tract left right asymmetry	GO:0071907	10	0.020
response to organic cyclic compound	GO:0014070	51	0.020
regulation of circadian sleep wake cycle sleep	GO:0045187	1	0.020
mitotic g2 dna damage checkpoint	GO:0007095	3	0.020
regulation of catalytic activity	GO:0050790	55	0.020
olfactory placode development	GO:0071698	12	0.020
response to carbohydrate	GO:0009743	3	0.020
catecholamine biosynthetic process	GO:0042423	2	0.020
regulation of jak stat cascade	GO:0046425	3	0.020
muscle fiber development	GO:0048747	52	0.020	Zebrafish
tube formation	GO:0035148	25	0.020
erythrocyte development	GO:0048821	24	0.020
positive regulation of signal transduction	GO:0009967	56	0.020
developmental growth involved in morphogenesis	GO:0060560	86	0.020	Zebrafish
definitive hemopoiesis	GO:0060216	18	0.020
response to corticosteroid	GO:0031960	1	0.020
negative regulation of cell cycle	GO:0045786	14	0.019
organonitrogen compound metabolic process	GO:1901564	74	0.019
neuromuscular synaptic transmission	GO:0007274	2	0.019	Zebrafish Worm
negative regulation of cellular metabolic process	GO:0031324	77	0.019
positive regulation of cellular component biogenesis	GO:0044089	3	0.019
morphogenesis of embryonic epithelium	GO:0016331	30	0.019
protein metabolic process	GO:0019538	183	0.019
regulation of circadian sleep wake cycle	GO:0042749	1	0.019
regulation of multicellular organism growth	GO:0040014	4	0.019
response to ketone	GO:1901654	1	0.019
aorta development	GO:0035904	4	0.019
retinal ganglion cell axon guidance	GO:0031290	35	0.019
anatomical structure arrangement	GO:0048532	2	0.019
programmed cell death	GO:0012501	119	0.019
serotonin biosynthetic process	GO:0042427	1	0.019
response to drug	GO:0042493	3	0.019
positive regulation of cell communication	GO:0010647	56	0.019
circadian behavior	GO:0048512	5	0.018
regulation of cell migration involved in sprouting angiogenesis	GO:0090049	3	0.018
cellular amino acid metabolic process	GO:0006520	7	0.018
adherens junction organization	GO:0034332	4	0.018
regulation of cell communication	GO:0010646	232	0.018
cell cycle g1 s phase transition	GO:0044843	1	0.018
striated muscle cell development	GO:0055002	108	0.018	Zebrafish
circadian sleep wake cycle process	GO:0022410	2	0.018
negative regulation of dna metabolic process	GO:0051053	4	0.018
embryonic heart tube formation	GO:0003144	1	0.018
axon midline choice point recognition	GO:0016199	4	0.018
somatic muscle development	GO:0007525	4	0.018
primitive hemopoiesis	GO:0060215	27	0.018
cellular protein modification process	GO:0006464	100	0.018
regulation of inflammatory response	GO:0050727	2	0.018
negative regulation of biosynthetic process	GO:0009890	55	0.018
endothelial cell migration	GO:0043542	19	0.018
optic cup morphogenesis involved in camera type eye development	GO:0002072	7	0.018
regulation of protein modification by small protein conjugation or removal	GO:1903320	3	0.018
otolith development	GO:0048840	32	0.018
regulation of axon extension involved in axon guidance	GO:0048841	6	0.017
positive regulation of tyrosine phosphorylation of stat protein	GO:0042531	1	0.017
erk1 and erk2 cascade	GO:0070371	4	0.017
phagocytosis engulfment	GO:0006911	1	0.017
single organism metabolic process	GO:0044710	217	0.017
positive regulation of tyrosine phosphorylation of stat3 protein	GO:0042517	1	0.017
pronuclear migration	GO:0035046	1	0.017
transport	GO:0006810	220	0.017	Zebrafish Mouse Worm
cerebellar granular layer development	GO:0021681	3	0.017
cellular component assembly	GO:0022607	170	0.017	Zebrafish
limbic system development	GO:0021761	16	0.017
single organism behavior	GO:0044708	24	0.017
neural crest cell differentiation	GO:0014033	72	0.017
posterior lateral line neuromast mantle cell differentiation	GO:0048924	1	0.017
negative regulation of cell development	GO:0010721	26	0.017
regulation of ion transmembrane transporter activity	GO:0032412	2	0.017
pancreatic d cell development	GO:0003324	1	0.016
monovalent inorganic cation transport	GO:0015672	42	0.016
regulation of canonical wnt signaling pathway	GO:0060828	34	0.016
immune system development	GO:0002520	191	0.016

chrna6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.053

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