Danio rerio

147 known processes

chrna1

cholinergic receptor, nicotinic, alpha polypeptide 1

(Aliases: nic1,zgc:86593,MGC86593)

chrna1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal muscle thin filament assemblyGO:003024040.996
striated muscle cell differentiationGO:00511461290.995
myofibril assemblyGO:0030239480.990
Zebrafish
muscle cell differentiationGO:00426921390.973
muscle structure developmentGO:00610611960.972
myosin filament assemblyGO:003103460.970
muscle cell developmentGO:00550011150.968
skeletal muscle contractionGO:000300950.967
Human
cellular component morphogenesisGO:00329893360.959
regulation of sarcomere organizationGO:006029720.954
sarcomerogenesisGO:004876940.905
myosin filament organizationGO:003103360.903
skeletal myofibril assemblyGO:001486670.866
voluntary skeletal muscle contractionGO:000301040.825
skeletal muscle myosin thick filament assemblyGO:003024150.817
striated muscle myosin thick filament assemblyGO:007168860.771
reactive nitrogen species metabolic processGO:200105700.756
cellular component assemblyGO:00226071700.749
Zebrafish
organelle assemblyGO:00709251100.742
Zebrafish
nitric oxide biosynthetic processGO:000680920.721
striated muscle cell developmentGO:00550021080.721
motor neuron axon guidanceGO:0008045230.715
larval developmentGO:000216420.705
musculoskeletal movementGO:005088180.701
Human
response to chemicalGO:00422213200.692
regulation of developmental processGO:00507932470.657
response to external stimulusGO:00096052640.619
multicellular organismal movementGO:005087980.601
Human
regulation of organelle assemblyGO:190211540.598
muscle system processGO:0003012200.553
Human
cellular component assembly involved in morphogenesisGO:00109271070.548
Zebrafish
sarcomere organizationGO:0045214260.547
ion transmembrane transportGO:0034220910.536
reactive oxygen species biosynthetic processGO:190340910.509
skeletal muscle tissue developmentGO:0007519670.501
regulation of muscle contractionGO:000693730.496
circulatory system processGO:0003013870.486
twitch skeletal muscle contractionGO:001472140.470
system processGO:00030081850.460
Human
axonogenesisGO:00074091520.452
behaviorGO:0007610740.447
Worm
striated muscle tissue developmentGO:00147061100.447
skeletal system developmentGO:00015011810.427
regulation of glutamate receptor signaling pathwayGO:190044910.420
cellular macromolecule biosynthetic processGO:00346452240.393
cardiac muscle myosin thick filament assemblyGO:007169010.380
regulation of transmembrane transportGO:0034762180.374
cell projection morphogenesisGO:00488582440.361
regionalizationGO:00030022740.360
regulation of behaviorGO:0050795240.353
Worm
regulation of skeletal muscle fiber developmentGO:004874220.346
membrane repolarizationGO:008600920.330
neuron projection developmentGO:00311751800.324
heart morphogenesisGO:00030071560.322
muscle tissue developmentGO:00605371100.319
chemotaxisGO:00069351040.319
regulation of membrane potentialGO:0042391230.311
regulation of cardiac muscle contractionGO:005511720.311
skeletal muscle organ developmentGO:0060538780.295
ventricular cardiac myofibril assemblyGO:005500540.293
cell morphogenesis involved in neuron differentiationGO:00486671630.292
axon developmentGO:00615641660.290
cell projection organizationGO:00300302840.284
endochondral bone morphogenesisGO:006035080.282
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.280
cardiac muscle cell differentiationGO:0055007300.279
connective tissue developmentGO:0061448990.278
regulation of multicellular organismal processGO:00512392770.277
regulation of axonogenesisGO:0050770320.275
skeletal muscle fiber developmentGO:0048741350.275
myotube cell developmentGO:0014904350.273
larval locomotory behaviorGO:000834550.266
cellular response to chemical stimulusGO:00708871570.265
lipid storageGO:001991510.265
muscle organ developmentGO:00075171010.262
positive regulation of muscle cell differentiationGO:005114910.260
actomyosin structure organizationGO:0031032530.258
Zebrafish
nitric oxide metabolic processGO:004620920.254
neuron developmentGO:00486662620.228
growth plate cartilage morphogenesisGO:000342210.228
locomotionGO:00400113130.222
cytoskeleton organizationGO:0007010960.222
Zebrafish
cellular response to organic cyclic compoundGO:0071407380.217
regulation of epithelial cell proliferationGO:005067830.213
positive regulation of heart contractionGO:004582320.204
response to drugGO:004249330.204
regulation of skeletal muscle tissue developmentGO:004864140.204
actin filament based processGO:0030029640.202
Zebrafish
regulation of ion transportGO:0043269220.199
ventricular cardiac muscle tissue morphogenesisGO:005501020.198
regulation of system processGO:0044057400.197
pigmentationGO:0043473850.196
regulation of ion transmembrane transportGO:0034765180.195
regulation of biological qualityGO:00650082630.191
nitrogen compound metabolic processGO:00068073190.190
cation transmembrane transportGO:0098655650.180
positive regulation of striated muscle cell differentiationGO:005115510.179
positive regulation of macromolecule biosynthetic processGO:0010557590.178
single organism localizationGO:19025782250.174
segmentationGO:0035282970.170
regulation of signalingGO:00230512350.168
cellular nitrogen compound biosynthetic processGO:00442712180.163
heart processGO:0003015710.160
anterior posterior pattern specificationGO:00099521520.159
kidney developmentGO:0001822920.157
transportGO:00068102200.154
regulation of neuron differentiationGO:0045664560.153
gene expressionGO:00104672520.153
adult behaviorGO:003053420.150
response to organic substanceGO:00100331530.150
biosynthetic processGO:00090582940.148
neuron differentiationGO:00301823530.146
regulation of cellular biosynthetic processGO:00313262450.146
actin cytoskeleton organizationGO:0030036630.144
Zebrafish
regulation of cell differentiationGO:00455951420.144
rna localizationGO:000640340.141
mitochondrion organizationGO:000700540.135
response to endogenous stimulusGO:0009719830.135
transmembrane transportGO:00550851200.131
negative regulation of biological processGO:00485193040.130
blood circulationGO:0008015870.129
positive regulation of skeletal muscle tissue developmentGO:004864310.129
muscle contractionGO:0006936180.128
Human
cellular protein modification processGO:00064641000.125
cardiocyte differentiationGO:0035051440.125
growth plate cartilage developmentGO:000341720.123
morphogenesis of an epitheliumGO:00020093330.123
regulation of rna biosynthetic processGO:20011412130.120
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031010.116
single organism organelle organizationGO:19025891990.115
Zebrafish
generation of neuronsGO:00486993850.114
atp catabolic processGO:000620040.110
regulation of myotube differentiationGO:001083020.108
intracellular mrna localizationGO:000829810.105
heart developmentGO:00075073130.105
regulation of growthGO:0040008420.104
regulation of nitrogen compound metabolic processGO:00511712510.103
cardiac myofibril assemblyGO:005500390.103
cell morphogenesisGO:00009022890.102
cartilage morphogenesisGO:0060536130.102
regulation of ion transmembrane transporter activityGO:003241220.100
heart contractionGO:0060047710.100
cellular response to antibioticGO:007123610.099
regulation of cell projection organizationGO:0031344440.099
heart loopingGO:0001947940.099
oocyte anterior posterior axis specificationGO:000731440.098
pole plasm assemblyGO:000731540.097
renal system developmentGO:0072001940.097
cell morphogenesis involved in differentiationGO:00009041950.095
reproductionGO:0000003400.095
Worm
positive regulation of cellular metabolic processGO:0031325940.095
sensory organ developmentGO:00074233930.094
cell migrationGO:00164772370.094
regulation of cell growthGO:0001558290.093
purine nucleoside monophosphate catabolic processGO:000912840.093
taxisGO:00423301090.093
somite developmentGO:0061053960.093
axon extensionGO:0048675450.092
synaptic transmission cholinergicGO:000727140.090
negative regulation of protein phosphorylationGO:000193340.090
regulation of cell projection assemblyGO:006049140.089
cell matrix adhesionGO:000716040.087
muscle fiber developmentGO:0048747520.087
cellular response to organic substanceGO:00713101050.086
regulation of blood circulationGO:1903522320.086
cytoplasm organizationGO:000702840.084
cell motilityGO:00488702440.083
organelle organizationGO:00069962270.083
Zebrafish
glomerulus developmentGO:0032835270.082
response to activityGO:0014823140.082
pharyngeal muscle developmentGO:004328240.081
head developmentGO:00603223030.079
single organism metabolic processGO:00447102170.078
cartilage developmentGO:0051216960.077
regulation of striated muscle contractionGO:000694220.076
myotube differentiationGO:0014902450.076
signal transductionGO:00071654550.075
protein complex assemblyGO:0006461300.074
organic substance biosynthetic processGO:19015762890.074
developmental growth involved in morphogenesisGO:0060560860.073
cellular aromatic compound metabolic processGO:00067252950.073
lamellipodium assemblyGO:003003210.073
nucleic acid templated transcriptionGO:00976591810.072
regulation of metabolic processGO:00192223590.071
regulation of biosynthetic processGO:00098892500.070
regulation of cell developmentGO:00602841000.070
positive regulation of cellular biosynthetic processGO:0031328680.069
regulation of multicellular organismal developmentGO:20000262230.069
muscle hypertrophyGO:001489620.069
digestive system developmentGO:00551232890.067
developmental maturationGO:0021700340.067
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.066
cognitionGO:005089010.066
eye developmentGO:00016542770.066
aromatic compound biosynthetic processGO:00194382170.066
notochord developmentGO:0030903540.066
amine metabolic processGO:000930820.066
regulation of localizationGO:00328791040.065
response to corticosteroidGO:003196010.065
establishment of localizationGO:00512342440.065
astrocyte differentiationGO:004870810.065
macromolecule biosynthetic processGO:00090592270.065
embryonic organ developmentGO:00485683810.065
central nervous system developmentGO:00074173870.064
cell surface receptor signaling pathwayGO:00071663250.064
negative regulation of protein kinase activityGO:000646940.064
outflow tract morphogenesisGO:000315110.063
regulation of protein import into nucleusGO:004230620.063
regulation of reactive oxygen species metabolic processGO:200037720.063
cellular amino acid metabolic processGO:000652070.063
multi organism processGO:00517041340.062
Worm
bone developmentGO:0060348140.062
neuromuscular synaptic transmissionGO:000727420.061
response to stressGO:00069502630.061
regulation of reproductive processGO:200024140.061
Worm
cell part morphogenesisGO:00329902460.061
ion transportGO:00068111140.060
multi organism reproductive processGO:0044703360.059
Worm
transcription dna templatedGO:00063511810.058
response to coldGO:000940940.058
regulation of nervous system developmentGO:0051960900.058
endochondral bone growthGO:000341620.058
lymphoid lineage cell migration into thymusGO:009753540.058
histone h3 k4 methylationGO:005156820.058
developmental growthGO:00485891660.057
regulation of nucleobase containing compound metabolic processGO:00192192500.057
positive regulation of transportGO:005105020.057
reactive oxygen species metabolic processGO:007259360.057
protein methylationGO:0006479130.056
negative regulation of epithelial cell proliferationGO:005068010.056
regulation of transmembrane transporter activityGO:002289820.056
basement membrane assemblyGO:007083130.056
nucleobase containing compound metabolic processGO:00061392740.055
heterocycle biosynthetic processGO:00181302150.055
heterocycle metabolic processGO:00464832900.055
pronephros developmentGO:0048793690.055
cellular nitrogen compound metabolic processGO:00346412900.054
cell cell signalingGO:0007267520.053
single organism transportGO:00447652060.053
regulation of anatomical structure morphogenesisGO:00226031300.053
regulation of macromolecule biosynthetic processGO:00105562250.052
regulation of primary metabolic processGO:00800903110.052
growthGO:00400071740.052
response to methanolGO:003398640.052
regulation of cellular metabolic processGO:00313233200.052
regulation of transcription dna templatedGO:00063552130.051
regulation of synapse organizationGO:005080730.051
cellular response to extracellular stimulusGO:003166820.050
cardiac chamber developmentGO:0003205190.049
neuron projection morphogenesisGO:00488121610.049
regulation of bone mineralizationGO:003050020.049
histone lysine methylationGO:0034968120.049
embryo development ending in birth or egg hatchingGO:00097922710.049
embryonic heart tube developmentGO:00350501330.049
rna metabolic processGO:00160702190.048
macromolecule modificationGO:00434121110.048
cellular macromolecule metabolic processGO:00442603910.048
regulation of transporter activityGO:003240920.048
blood vessel developmentGO:00015682460.048
defense responseGO:0006952470.048
deathGO:00162651210.048
maintenance of locationGO:005123540.047
positive regulation of biological processGO:00485182530.046
positive regulation of cell cycleGO:004578730.046
single organism cellular localizationGO:1902580460.045
cellular amino acid biosynthetic processGO:000865220.045
neurotransmitter transportGO:000683620.045
programmed cell deathGO:00125011190.045
regulation of response to stimulusGO:00485832690.045
Worm
cellular component movementGO:00069283350.045
cellular response to stressGO:0033554620.044
protein complex biogenesisGO:0070271300.044
oxidative phosphorylationGO:000611910.044
regulation of circadian sleep wake cycleGO:004274910.044
negative regulation of kinase activityGO:003367340.044
tube morphogenesisGO:00352393490.044
positive regulation of nitrogen compound metabolic processGO:0051173690.043
post embryonic organ developmentGO:004856940.043
regulation of response to oxidative stressGO:190288220.043
positive regulation of blood circulationGO:190352420.042
cellular localizationGO:0051641970.042
regulation of axon extensionGO:0030516240.042
methylationGO:0032259220.042
positive regulation of macromolecule metabolic processGO:0010604930.041
response to glucocorticoidGO:005138410.041
cellular amine metabolic processGO:004410620.041
response to alcoholGO:0097305140.041
regulation of heart contractionGO:0008016320.041
circadian sleep wake cycle processGO:002241020.040
lymphoid lineage cell migrationGO:009753440.040
nephron tubule epithelial cell differentiationGO:007216010.040
peptidyl lysine methylationGO:001802230.039
response to woundingGO:00096111160.039
circadian sleep wake cycle sleepGO:005080210.039
regulation of metal ion transportGO:001095940.039
neuron projection guidanceGO:0097485860.038
regulation of receptor activityGO:001046920.038
chordate embryonic developmentGO:00430092710.038
er nucleus signaling pathwayGO:000698420.037
cellular macromolecule localizationGO:0070727210.037
cellular response to hormone stimulusGO:0032870390.037
protein metabolic processGO:00195381830.037
positive regulation of nucleic acid templated transcriptionGO:1903508570.037
cellular protein complex assemblyGO:0043623190.036
positive regulation of cellular amino acid metabolic processGO:004576400.036
neuronal action potentialGO:0019228180.036
Human
positive regulation of cellular amine metabolic processGO:003324000.036
muscle cell migrationGO:001481240.036
regulation of protein targetingGO:190353320.036
single organism reproductive processGO:0044702400.035
platelet formationGO:003022010.035
nucleoside monophosphate catabolic processGO:000912540.035
synaptic transmissionGO:0007268350.035
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.035
regulation of skeletal muscle cell differentiationGO:200101410.035
cardiac muscle contractionGO:006004860.035
fatty acid oxidationGO:001939510.034
regulation of cell communicationGO:00106462320.034
sexual reproductionGO:0019953360.034
mechanosensory behaviorGO:000763820.034
small molecule metabolic processGO:0044281770.034
digestive tract developmentGO:00485652650.033
cell cycle arrestGO:000705010.033
melanocyte differentiationGO:0030318260.033
cellular calcium ion homeostasisGO:0006874130.033
positive regulation of rna metabolic processGO:0051254590.033
regulation of cellular amine metabolic processGO:003323800.033
histone methylationGO:0016571130.033
response to alkaloidGO:004327920.033
negative regulation of signal transductionGO:0009968940.032
response to nutrientGO:000758430.032
positive regulation of cellular component biogenesisGO:004408930.032
regulation of dendrite developmentGO:005077330.032
macromolecular complex subunit organizationGO:0043933740.032
response to antibioticGO:004667710.032
circadian sleep wake cycleGO:004274520.031
negative regulation of protein serine threonine kinase activityGO:007190120.031
response to vitaminGO:003327330.031
nephron developmentGO:0072006310.031
microtubule organizing center organizationGO:003102310.031
meiotic nuclear divisionGO:000712640.031
modulation by virus of host morphology or physiologyGO:001904810.031
convergent extension involved in organogenesisGO:0060029100.030
positive regulation of rna biosynthetic processGO:1902680570.030
regulation of circadian sleep wake cycle sleepGO:004518710.030
regulation of nucleic acid templated transcriptionGO:19035062130.030
regulation of rna metabolic processGO:00512522240.030
urogenital system developmentGO:0001655970.030
lipid metabolic processGO:0006629520.030
organic cyclic compound biosynthetic processGO:19013622230.030
cellular response to toxic substanceGO:009723710.029
response to organic cyclic compoundGO:0014070510.029
lymphocyte homeostasisGO:000226010.029
regulation of transportGO:0051049450.029
inorganic cation transmembrane transportGO:0098662500.029
larval behaviorGO:003053750.029
proteasomal protein catabolic processGO:001049820.029
maternal determination of anterior posterior axis embryoGO:000835840.028
organonitrogen compound metabolic processGO:1901564740.028
positive regulation of biosynthetic processGO:0009891680.028
bmp signaling pathwayGO:0030509520.028
sequestering of calcium ionGO:005120830.028
nucleic acid metabolic processGO:00903042440.028
positive regulation of transcription dna templatedGO:0045893570.028
muscle attachmentGO:001620390.027
auditory receptor cell morphogenesisGO:000209340.027
single organism behaviorGO:0044708240.027
spermatid developmentGO:000728620.027
biological adhesionGO:0022610400.027
mesenchyme developmentGO:00604851270.026
hematopoietic or lymphoid organ developmentGO:00485341910.026
response to biotic stimulusGO:0009607970.026
cellular response to growth factor stimulusGO:0071363390.026
cellular response to external stimulusGO:007149620.026
sensory system developmentGO:0048880760.026
regulation of nucleocytoplasmic transportGO:004682220.026
regulation of cellular component organizationGO:0051128860.025
regulation of circadian rhythmGO:004275240.025
cardiac muscle tissue developmentGO:0048738480.025
regulation of protein transportGO:005122330.025
lipid homeostasisGO:005508830.025
regulation of fatty acid metabolic processGO:001921710.025
multicellular organism reproductionGO:0032504350.025
Worm
immune system processGO:00023762410.025
regulation of hematopoietic progenitor cell differentiationGO:190153210.025
cytokinesisGO:000091030.025
anterior posterior axis specificationGO:0009948200.025
oocyte developmentGO:0048599140.025
nephron epithelium morphogenesisGO:007208810.025
cardiac muscle fiber developmentGO:004873930.024
cellular biosynthetic processGO:00442492860.024
regulation of protein bindingGO:004339330.024
slow twitch skeletal muscle fiber contractionGO:003144430.024
multicellular organismal signalingGO:0035637220.024
Human
cellular ketone metabolic processGO:0042180110.024
cellular response to endogenous stimulusGO:0071495680.024
positive regulation of muscle organ developmentGO:004863610.023
epithelial tube morphogenesisGO:00605621480.023
cell maturationGO:0048469230.023
agingGO:000756820.023
ear developmentGO:00435831270.023
nuclear importGO:005117030.023
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.023
regulation of mrna splicing via spliceosomeGO:004802430.023
regulation of neurogenesisGO:0050767870.023
regulation of bindingGO:005109830.022
neuron migrationGO:0001764220.022
positive regulation of epithelial cell proliferationGO:005067910.022
inner ear morphogenesisGO:0042472630.022
actin filament based movementGO:003004810.022
macromolecular complex assemblyGO:0065003350.022
cellular response to starvationGO:000926710.022
positive regulation of protein kinase b signalingGO:005189710.022
macromolecule methylationGO:0043414190.022
inorganic ion transmembrane transportGO:0098660570.021
regulation of striated muscle cell differentiationGO:005115360.021
lateral line system developmentGO:0048925760.021
blastoderm segmentationGO:000735060.021
negative regulation of cellular processGO:00485232830.021
cardiac muscle tissue morphogenesisGO:005500870.021
regulation of response to cytokine stimulusGO:006075930.021
muscle cell fate commitmentGO:004269390.020
cell projection assemblyGO:0030031640.020
lamellipodium organizationGO:009758110.020
vasculature developmentGO:00019442780.020
regulation of neurotransmitter secretionGO:004692810.020
rna biosynthetic processGO:00327741810.020
calcium ion homeostasisGO:0055074190.020
regulation of nitric oxide mediated signal transductionGO:001074910.020
cellular response to methanolGO:007140540.019
extraocular skeletal muscle developmentGO:000207430.019
regulation of neurotransmitter transportGO:005158810.019
homeostatic processGO:00425921420.019
Human
fatty acid beta oxidationGO:000663510.019
determination of heart left right asymmetryGO:00613711170.019
kidney epithelium developmentGO:0072073230.019
atrial cardiac myofibril assemblyGO:005500420.019
pharynx developmentGO:006046550.019
regulation of cellular response to oxidative stressGO:190040720.019
response to vitamin b3GO:003355220.019
response to light stimulusGO:0009416460.019
multicellular organismal reproductive processGO:0048609350.019
Worm
nerve developmentGO:0021675450.019
oxoacid metabolic processGO:0043436310.019
phosphorylationGO:0016310690.018
pigment cell differentiationGO:0050931380.018
regulation of macromolecule metabolic processGO:00602553170.018
regulation of cell activationGO:005086510.018
protein localization to membraneGO:007265790.018
regulation of cellular amino acid metabolic processGO:000652100.018
skin developmentGO:0043588540.018
regulation of mrna processingGO:005068430.018
regulation of postsynaptic membrane potentialGO:006007810.018
cell growthGO:0016049570.018
transcription elongation from rna polymerase ii promoterGO:000636830.018
cellular response to nutrient levelsGO:003166920.018
developmental cell growthGO:0048588520.018
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.018
neurotransmitter secretionGO:000726920.018
camera type eye developmentGO:00430102220.018
cellular macromolecular complex assemblyGO:0034622240.018
regulation of signal transductionGO:00099662250.018
organism emergence from protective structureGO:007168440.018
positive regulation of dna templated transcription elongationGO:003278610.018
stem cell proliferationGO:007208940.018
regulation of protein localization to nucleusGO:190018020.017
determination of bilateral symmetryGO:00098552040.017
axon guidanceGO:0007411860.017
embryonic skeletal system developmentGO:0048706970.017
negative regulation of epithelial cell migrationGO:001063310.017
cell proliferationGO:0008283800.017
cellular response to radiationGO:007147840.017
cellular response to oxygen containing compoundGO:1901701200.017
regulation of cytoplasmic transportGO:190364940.017
negative regulation of gene expressionGO:0010629650.017
neural crest cell migrationGO:0001755420.017
regulation of tube sizeGO:003515020.017
negative regulation of multicellular organismal processGO:0051241690.017
gamete generationGO:0007276330.017
regulation of blood pressureGO:000821710.017
collagen metabolic processGO:003296320.017
response to hormoneGO:0009725480.017
cellular response to estrogen stimulusGO:0071391240.017
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
establishment of protein localization to organelleGO:007259440.017
apoptotic processGO:00069151160.016
regulation of cellular component sizeGO:0032535300.016

chrna1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.452
musculoskeletal system diseaseDOID:1700.057
muscle tissue diseaseDOID:6600.056
muscular diseaseDOID:008000000.056
myopathyDOID:42300.043
kidney diseaseDOID:55700.029
urinary system diseaseDOID:1800.029
intrinsic cardiomyopathyDOID:006003600.029
heart diseaseDOID:11400.029
cardiovascular system diseaseDOID:128700.029
cardiomyopathyDOID:005070000.029